FedInvent™ Patents
Patent Details for Tuesday, February 22, 2022
This page was updated on Thursday, February 24, 2022 at 02:14 AM GMT
Department of Health and Human Services (HHS)
| US 11253159 | Shusterman |
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| FUNDED BY |
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| APPLICANT(S) | Vladimir Shusterman (Pittsburgh, Pennsylvania) |
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| INVENTOR(S) | Vladimir Shusterman (Pittsburgh, Pennsylvania) |
| ABSTRACT | Modular, miniaturized cardiovascular sensors, systems, methods, and wearable devices for the non-obtrusive evaluation, monitoring, and high-fidelity mapping of cardiac mechanical and electromechanical forces and central arterial blood pressure are presented herein. The sensor manufacturing process is also presented. Using accelerometers, the sensors register body-surface (preferably torso-surface) movements and vibrations generated by cardiac forces. The sensors may contain single-use or reusable components, which may be exchanged to fit different body sizes, shapes, and anatomical locations; they may be incorporated into clothing, bands, straps, and other wearable arrangements. The invention presents a practical, noninvasive solution for electromechanical mapping of the heart, which is useful for a wide range of healthcare applications, including the remote monitoring of heart failure status and the guidance of cardiac resynchronization therapy. Exercise and cardiovascular fitness tracking applications are also presented. |
| FILED | Thursday, August 31, 2017 |
| APPL NO | 15/693141 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/021 (20130101) A61B 5/024 (20130101) A61B 5/029 (20130101) A61B 5/318 (20210101) A61B 5/352 (20210101) A61B 5/389 (20210101) A61B 5/0533 (20130101) A61B 5/0826 (20130101) A61B 5/1102 (20130101) A61B 5/02007 (20130101) A61B 5/02014 (20130101) A61B 5/02055 (20130101) Original (OR) Class A61B 5/02116 (20130101) A61B 5/02125 (20130101) A61B 5/4818 (20130101) A61B 5/4848 (20130101) A61B 5/4884 (20130101) A61B 5/6805 (20130101) A61B 5/6833 (20130101) A61B 5/7275 (20130101) A61B 8/04 (20130101) A61B 8/4236 (20130101) A61B 2560/0443 (20130101) A61B 2562/164 (20130101) A61B 2562/0219 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3627 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253489 | Palczewski et al. |
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| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Krzysztof Palczewski (Bay Village, Ohio); Philip Kiser (Cleveland, Ohio); Jianye Zhang (Cleveland, Ohio); Mohsen Badiee (Shaker Heights, Ohio); Gregory Tochtrop (Shaker Heights, Ohio) |
| ABSTRACT | A method of treating an ocular disorder in a subject in need thereof includes administering to the subject a therapeutically effective amount of a retinal sequestering compound of formula (I). |
| FILED | Tuesday, February 27, 2018 |
| APPL NO | 16/488890 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 31/137 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253503 | Milbrandt et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (Saint Louis, Missouri); Disarm Therapeutics, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Washington University (Saint Louis, Missouri); Disarm Therapeutics, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Jeffrey Milbrandt (Saint Louis, Missouri); Kow Essuman (Saint Louis, Missouri); Yo Sasaki (Brentwood, Missouri); Aaron DiAntonio (Olivette, Missouri); Xianrong Mao (Saint Louis, Missouri); Rajesh Devraj (Chesterfield, Missouri); Raul Eduardo Krauss (Chestnut Hill, Massachusetts); Robert Owen Hughes (Newtown, Connecticut) |
| ABSTRACT | The present disclosure provides compounds useful as inhibitors of SARM1 NADase activity, compositions thereof, and methods of using the same. The present disclosure provides compounds useful for treating a neurodegenerative or neurological disease or disorder, compositions thereof, and methods of using the same. |
| FILED | Friday, September 22, 2017 |
| APPL NO | 16/335754 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/41 (20130101) A61K 31/047 (20130101) A61K 31/145 (20130101) A61K 31/198 (20130101) A61K 31/437 (20130101) A61K 31/444 (20130101) A61K 31/566 (20130101) A61K 31/4375 (20130101) A61K 31/4439 (20130101) Original (OR) Class A61K 31/4535 (20130101) A61K 31/7048 (20130101) A61K 31/7084 (20130101) A61K 33/28 (20130101) A61K 33/30 (20130101) A61K 33/243 (20190101) A61K 33/245 (20130101) A61K 47/52 (20170801) A61K 47/55 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253506 | Veress |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| INVENTOR(S) | Livia A. Veress (Denver, Colorado) |
| ABSTRACT | The present invention includes compounds, compositions and methods for treating and/or preventing chlorine inhalation toxicity and/or injury in a subject subjected to chlorine inhalation. |
| FILED | Friday, August 17, 2018 |
| APPL NO | 16/104366 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/46 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 39/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253511 | Boger et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); THE UNITED STATES OF AMERICA, as represented by th (Washington, District of Columbia) |
| INVENTOR(S) | Ravit Boger (Baltimore, Maryland); Marc Ferrer (Potomac, Maryland); Juan Marugan (Gaithersburg, Maryland); Andres Dulcey Garcia (Gaithersburg, Maryland); Noel Terrence Southall (Potomac, Maryland); Xin Hu (Frederick, Maryland) |
| ABSTRACT | The present invention relates to the field of virology. More specifically, the present invention provides methods and compositions useful for prevention and treatment of human cytomegalovirus (CMV). In one embodiment, a pharmaceutical composition comprises (a) emetine or a derivative thereof; (b) a human cytomegalovirus (HCMV) drug; and (c) a pharmaceutically acceptable carrier. In certain embodiments, the pharmaceutical composition further comprises an adjuvant. In a specific embodiment, the HCMV drug is ganciclovir. In such embodiments, emetine is present at about 1/10 to about 1/100 the normal dosage for amebiasis. |
| FILED | Wednesday, January 04, 2017 |
| APPL NO | 16/068208 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 31/522 (20130101) A61K 31/522 (20130101) A61K 31/4745 (20130101) Original (OR) Class A61K 31/4745 (20130101) A61K 38/05 (20130101) A61K 38/05 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/20 (20180101) A61P 31/22 (20180101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253517 | O'Malley et al. |
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| FUNDED BY |
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| APPLICANT(S) | BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
| ASSIGNEE(S) | BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
| INVENTOR(S) | Bert W. O'Malley (Houston, Texas); David Michael Lonard (Pearland, Texas); Jin Wang (Sugar Land, Texas); Jianming Xu (Bellaire, Texas); Jianwei Chen (Houston, Texas) |
| ABSTRACT | Small molecule regulators of steroid receptor coactivator (SRC) family proteins are provided, as well as methods for their use in treating or preventing SRC-related diseases. The SRC-related diseases can include cancer, metabolic disorders, human immunodeficiency virus, neurodegenerative disorders, and/or inflammatory diseases. Also provided are methods for regulating SRC family proteins in a cell. |
| FILED | Thursday, November 21, 2019 |
| APPL NO | 16/691195 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/426 (20130101) A61K 31/506 (20130101) Original (OR) Class A61K 31/4184 (20130101) A61K 31/4402 (20130101) Heterocyclic Compounds C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101) C07D 409/12 (20130101) C07D 413/12 (20130101) C07D 417/12 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) C07D 498/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253522 | Ruggero et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Davide Ruggero (Emerald Hill, California); Hao Nguyen (San Francisco, California); Peter Carroll (San Francisco, California); Crystal Conn (Oakland, California) |
| ABSTRACT | In cancers such as prostate cancer, the combination of PTEN loss and activation of Myc activates an adaptive stress response that enables tumor cells to escape the stress of massively upregulated protein synthesis. This pro-survival response is mediated by the PERK-phosphorylated eIF2α axis of the UPR adaptive response. Agents that disrupt PERK-eIF2α pathways disrupt the adaptive response and lead to cancer cell death from uncontrolled growth. For example, ISRIB and derivatives may be employed as therapeutic agents to disrupt PERK-mediated adaptive mechanisms. Additionally PTEN loss and activation of Myc provides a diagnostic marker that enables better prognosis and the selection of amenable treatments. |
| FILED | Sunday, April 28, 2019 |
| APPL NO | 16/396723 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 33/57434 (20130101) G01N 2440/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253529 | Radtke |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (Baltimore, Maryland) |
| INVENTOR(S) | Katherine L. Radtke (Baltimore, Maryland) |
| ABSTRACT | The present invention is directed to compounds, methods and compositions for treating or preventing viral infections using nucleosides analogs. Specifically, the present invention provides for the design and synthesis of acyclic fleximer nucleoside analogues having increased flexibility and ability to alter their conformation structures to provide increased antiviral activity potential with the result of inhibiting flaviviruses, filoviruses and/or coronaviruses. |
| FILED | Friday, January 26, 2018 |
| APPL NO | 16/629057 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 31/675 (20130101) A61K 31/683 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253546 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); SEATTLE CHILDREN'S HOSPITAL (Seattle, Washington) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Seattle Children's Hospital (Seattle, Washington) |
| INVENTOR(S) | Yvonne Y. Chen (Los Angeles, California); Eugenia Zah (Los Angeles, California); Michael C. Jensen (Seattle, Washington) |
| ABSTRACT | A CD19-OR-CD20 chimeric antigen receptor (CAR) protein construct is provided. Also provided are nucleic acids encoding the CD19-OR-CD20 CAR; and methods of use, e.g. in the treatment of B cell malignancies. The CD19-OR-CD20 CAR of the invention is a bispecific CAR that can trigger T-cell activation upon detection of either CD19 or CD20 (or both). It is a single molecule that confers two-input recognition capability upon human T cells engineered to stably express this CAR. |
| FILED | Monday, December 14, 2015 |
| APPL NO | 15/535972 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 14/70596 (20130101) C07K 16/46 (20130101) C07K 16/2803 (20130101) C07K 16/2887 (20130101) C07K 2317/31 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253551 | Marban et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Eduardo Marban (Santa Monica, California); Romain Gallet (Paris, France) |
| ABSTRACT | Heart failure with preserved ejection fraction (HFpEF) is a disease condition characterized by heart failure (HF) signs and symptoms, but with normal or near normal left ventricular ejection fraction (LVEF) and is not responsive to standard therapy for treatment of HF. Described herein are compositions and methods related to use of cardiosphere derived cells (CDCs) and their exosomes to improve left ventricular structure, function and overall outcome. Administration of CDCs led to improved LV relaxation, lower LV end-diastolic pressure, decreased lung congestion and enhanced survival. Lower risk of arrhythmias in HFpEF was also observed following CDC administration. Improvement of diastolic dysfunction following administration of CDC-derived exosomes was observed, along with decreased mortality. In view of these salutary effects, CDCs and CDC-derived exosomes are beneficial in the treatment of HFpEF. |
| FILED | Wednesday, January 11, 2017 |
| APPL NO | 16/066014 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/34 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253559 | Thorne et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Stephen Howard Thorne (Pittsburgh, Pennsylvania); Daniel J. Byrd (Pittsburgh, Pennsylvania) |
| ABSTRACT | This disclosure relates to modified viruses, e.g., oncolytic vaccinia viruses, which have been modified to contain an exogenous nucleic acid that expresses a protein that modulates STAT3 activity. It is based, at least in part, on the discovery that vaccinia viruses modified to contain nucleic acid encoding PIAS3 and that express PIAS3 or a fragment thereof can inhibit STAT3 activity and enhance the anti-cancer activity of the vaccinia virus. Accordingly, this disclosure provides for oncolytic vaccinia viruses and methods of using them in the treatment of cancers. |
| FILED | Friday, January 18, 2019 |
| APPL NO | 16/252338 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/768 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/07 (20130101) C07K 14/16 (20130101) C07K 14/4702 (20130101) C07K 16/2827 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/104 (20130101) C12N 15/625 (20130101) C12N 2710/24132 (20130101) C12N 2710/24143 (20130101) Enzymes C12Y 301/03048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253560 | Deng et al. |
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| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Liang Deng (New York, New York); Jedd Wolchok (New York, New York); Taha Merghoub (New York, New York); Stewart Shuman (New York, New York); Peihong Dai (New York, New York); Weiyi Wang (New York, New York) |
| ABSTRACT | The present disclosure relates to modified vaccinia Ankara (MVA) virus or MVAΔE3L delivered intratumorally or systemically as an anticancer immunotherapeutic agent, alone, or in combination with one or more immune checkpoint blocking agents for the treatment of malignant solid tumors. Particular embodiments relate to mobilizing the host's immune system to mount an immune response against the tumor. |
| FILED | Monday, January 13, 2020 |
| APPL NO | 16/741634 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/768 (20130101) Original (OR) Class A61K 39/12 (20130101) A61K 39/3955 (20130101) A61K 39/3955 (20130101) A61K 2039/54 (20130101) A61K 2039/57 (20130101) A61K 2039/505 (20130101) A61K 2039/525 (20130101) A61K 2039/545 (20130101) A61K 2039/5254 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/2818 (20130101) C07K 16/2827 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/24122 (20130101) C12N 2710/24132 (20130101) C12N 2710/24134 (20130101) C12N 2710/24171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253569 | Portman |
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| FUNDED BY |
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| APPLICANT(S) | Seattle Children's Hospital (Seattle, Washington) |
| ASSIGNEE(S) | Seattle Children's Hospital (Seattle, Washington) |
| INVENTOR(S) | Michael A. Portman (Seattle, Washington) |
| ABSTRACT | The present invention relates to the discovery that etanercept reduces the rate of resistance to intravenous gamma globulin (IVIG) in subjects with acute Kawasaki disease (KD). In certain embodiments, the co-administration of etanercept and IVIG more effectively treats acute KD in subjects older than 12 months than IVIG alone. In other embodiments, the co-administration of etanercept and IVIG ameliorates coronary artery dilation in high risk subjects. |
| FILED | Thursday, May 02, 2019 |
| APPL NO | 16/401698 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/05 (20130101) A61K 31/25 (20130101) A61K 31/047 (20130101) A61K 31/60 (20130101) A61K 31/192 (20130101) A61K 31/717 (20130101) A61K 31/718 (20130101) A61K 31/7016 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 39/395 (20130101) A61K 39/3955 (20130101) A61K 39/39516 (20130101) A61K 47/02 (20130101) A61K 47/12 (20130101) A61K 47/36 (20130101) A61K 47/183 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/00 (20180101) Peptides C07K 16/06 (20130101) C07K 16/241 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253588 | Leeper et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Nicholas J. Leeper (Stanford, California); Irving L. Weissman (Stanford, California) |
| ABSTRACT | An effective combined dose of an anti-CD47 agent and an anti-TNF agent is administered to the subject in a dose and for a period of time effective to stabilize, prevent or reduce atherosclerotic plaque in the individual. |
| FILED | Thursday, February 25, 2016 |
| APPL NO | 15/551881 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/17 (20130101) A61K 38/179 (20130101) A61K 38/1709 (20130101) A61K 38/1793 (20130101) A61K 39/3955 (20130101) Original (OR) Class A61K 39/39541 (20130101) A61K 39/39541 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) Peptides C07K 16/241 (20130101) C07K 16/2803 (20130101) C07K 2317/24 (20130101) C07K 2317/76 (20130101) C07K 2317/732 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253589 | Weiner et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Howard Weiner (Brookline, Massachusetts); Francisco J. Quintana (Jamaica Plain, Massachusetts) |
| ABSTRACT | Methods for identifying compounds that modulate the generation of regulatory T cells (Treg) in vivo and in vitro, i.e., compounds that act on the transcription factors that increase or decrease expression of Foxp3. |
| FILED | Thursday, October 12, 2017 |
| APPL NO | 15/782606 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/135 (20130101) A61K 31/137 (20130101) A61K 31/357 (20130101) A61K 31/405 (20130101) A61K 31/407 (20130101) A61K 31/427 (20130101) A61K 31/4045 (20130101) A61K 35/17 (20130101) A61K 39/3955 (20130101) Original (OR) Class A61K 2035/122 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2501/38 (20130101) C12N 2501/60 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253600 | Mejia Oneto et al. |
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| FUNDED BY |
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| APPLICANT(S) | TAMBO, INC. (San Francisco, California); THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| ASSIGNEE(S) | TAMBO, INC. (San Francisco, California); THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| INVENTOR(S) | Jose Manuel Mejia Oneto (San Francisco, California); Nathan Yee (San Francisco, California); Maksim Royzen (San Francisco, California); Sangeetha Srinivasan (San Francisco, California); Ethan Miller (San Francisco, California) |
| ABSTRACT | Cyclooctene conjugates of therapeutic or diagnostic agents have improved aqueous solubility and can release the agents upon contact with a tetrazine-containing biomaterial. The cyclooctene conjugates provide site-selective delivery of agents at the location of the tetrazine-containing biomaterial in a subject. The compositions and methods have applications in the treatment of various diseases or conditions including cancer, tumor growths, and bacterial infections. |
| FILED | Friday, April 06, 2018 |
| APPL NO | 16/603471 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/61 (20170801) A61K 47/542 (20170801) A61K 47/545 (20170801) Original (OR) Class A61K 49/0041 (20130101) A61K 49/0043 (20130101) A61K 49/0052 (20130101) A61K 49/0054 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253612 | Hinderer et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Christian Hinderer (Philadelphia, Pennsylvania); James M. Wilson (Philadelphia, Pennsylvania) |
| ABSTRACT | A suspension useful for AAV9-mediated intrathecal and/or systemic delivery of an expression cassette containing a hIDS gene is provided herein. Also provided are methods and kits containing these vectors and compositions useful for treating Hunter syndrome and the symptoms associated with Hunter syndrome. |
| FILED | Friday, April 14, 2017 |
| APPL NO | 16/093413 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Original (OR) Class A61K 48/0075 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 15/85 (20130101) C12N 15/86 (20130101) C12N 15/113 (20130101) C12N 2750/14143 (20130101) C12N 2800/22 (20130101) C12N 2830/15 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) Enzymes C12Y 301/06013 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254156 | Mahajan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Chaitanya G. Mahajan (Rochester, New York); Denis Cormier (Pittsford, New York); Mark Irving (Rochester, New York); Scott Williams (Livonia, New York); David Borkholder (Canandaigua, New York); Ahmed Alfadhel (Rochester, New York) |
| ASSIGNEE(S) | Rochester Institute of Technology (Rochester, New York) |
| INVENTOR(S) | Chaitanya G. Mahajan (Rochester, New York); Denis Cormier (Pittsford, New York); Mark Irving (Rochester, New York); Scott Williams (Livonia, New York); David Borkholder (Canandaigua, New York); Ahmed Alfadhel (Rochester, New York) |
| ABSTRACT | An approach to printing a nickel precursor ink on a wide range of substrates for electronics and magnetic applications is disclosed. The nickel ink reduces to elemental nickel following heating. The ink was printed using an ultrasonic aerosol printing technique. By sintering the nickel precursor ink in the presence of a homogeneous magnetic field, the reduced nickel complex formed continuously aligned nickel nanofibers axially aligned with the direction of the magnetic field. The fabrication of aligned interlayered nanofiber films provides opportunities to produce structures with enhanced isotropic electrical and magnetic properties. The resistivity of the film was found to be as low as 0.56 mΩ·cm, and the saturation magnetization was measured to be 30 emu/g, which is comparable to bulk Ni. Magnetic anisotropy was induced with an easy axis along the direction of the applied magnetic field with soft magnetic properties. |
| FILED | Thursday, April 18, 2019 |
| APPL NO | 16/388459 |
| ART UNIT | 2853 — Printing/Measuring and Testing |
| CURRENT CPC | Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 2/035 (20130101) Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 1/22 (20130101) Original (OR) Class B41M 7/0081 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254654 | Hathaway et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Nate Hathaway (Chapel Hill, North Carolina); Jian Jin (New York, New York); Ian MacDonald (Durham, North Carolina); Kyle Butler (Salt Lake City, Utah) |
| ABSTRACT | The present disclosure relates to chemical compounds that inhibit HP1-mediated heterochromatin formation, pharmaceutical compositions containing such compounds, methods of identifying such compounds, and their use in the treatment of disorders related to heterochromatin formation such as, for example, a disorder of cellular proliferation (e.g., cancer). This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Friday, June 29, 2018 |
| APPL NO | 16/622073 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 401/12 (20130101) C07D 401/14 (20130101) Original (OR) Class C07D 495/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6875 (20130101) G01N 33/57496 (20130101) G01N 2500/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254662 | Morris et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The USA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Joel Morris (Rockville, Maryland); Donn G. Wishka (Middletown, Maryland); Omar Diego Lopez (Walkersville, Maryland) |
| ABSTRACT | Halogenated analogs of 5-aza-2′-deoxycytidine, such as halogenated analogs of 5-aza-4′-thio-2′-deoxycytidine (5-aza-T-dCyd) are described. Pharmaceutical compositions including a halogenated analog and methods of using the halogenated analogs to inhibit neoplasia are described. In some examples, the halogenated analogs have a structure according to formula Ia, or a stereoisomer, tautomer, or pharmaceutically acceptable salt thereof: |
| FILED | Wednesday, June 09, 2021 |
| APPL NO | 17/343350 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 409/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254667 | Starczynowski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Daniel T. Starczynowski (Cincinnati, Ohio); Craig J. Thomas (Gaithersburg, Maryland); Garrett Rhyasen (Burlington, Massachusetts); Katelyn Melgar (Cincinnati, Ohio); Morgan MacKenzie Walker (New Haven, Connecticut); Jian-kang Jiang (Columbia, Maryland) |
| ABSTRACT | Some embodiments of the invention include inventive compounds (e.g., compounds of Formula (I)). Other embodiments include compositions (e.g., pharmaceutical compositions) comprising the inventive compound. Still other embodiments of the invention include compositions (e.g., pharmaceutical compositions) for treating, for example, certain diseases using the inventive compounds. Some embodiments include methods of using the inventive compound (e.g., in compositions or in pharmaceutical compositions) for administering and treating (e.g., diseases such as cancer or blood disorders). Further embodiments include methods for making the inventive compounds. Additional embodiments of the invention are also discussed herein. |
| FILED | Wednesday, August 16, 2017 |
| APPL NO | 16/326571 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254702 | Sharpless et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | K. Barry Sharpless (La Jolla, California); Peng Wu (San Diego, California); Suhua Li (San Diego, California); Zilei Liu (San Diego, California); Bing Gao (San Diego, California) |
| ABSTRACT | Thionyl tetrafluoride gas reacts efficiently with primary amines to form reactive iminosulfur oxydifluoride compounds. These dual SVI—F loaded iminosulfur oxydifluoride compounds, in turn, readily react with secondary amines or aryloxy silyl ethers (ArO—SiR3), yielding the corresponding fused heteroatom-linked substrates. Iminosulfur oxyfluoride polymers also are provided by disclosed methods. |
| FILED | Wednesday, November 29, 2017 |
| APPL NO | 16/464988 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/549 (20170801) A61K 47/6807 (20170801) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/07 (20130101) Acyclic or Carbocyclic Compounds C07C 205/04 (20130101) C07C 381/10 (20130101) C07C 2601/14 (20170501) C07C 2603/26 (20170501) C07C 2603/74 (20170501) Heterocyclic Compounds C07D 205/04 (20130101) C07D 207/48 (20130101) C07D 209/14 (20130101) C07D 211/96 (20130101) C07D 241/04 (20130101) C07D 265/30 (20130101) C07D 267/14 (20130101) C07D 285/10 (20130101) C07D 295/26 (20130101) C07D 309/02 (20130101) C07D 311/02 (20130101) C07D 311/46 (20130101) C07D 327/10 (20130101) C07D 405/04 (20130101) C07D 405/14 (20130101) C07D 413/04 (20130101) C07D 417/06 (20130101) C07D 451/04 (20130101) C07D 471/08 (20130101) C07D 473/34 (20130101) C07D 493/14 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/1804 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/06 (20130101) C07H 21/00 (20130101) Steroids C07J 41/005 (20130101) C07J 41/0072 (20130101) Original (OR) Class C07J 43/003 (20130101) C07J 51/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254713 | Roland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Kenneth Roland (Mesa, Arizona); Amanda M. Tafoya (Laveen, Arizona) |
| ABSTRACT | In certain embodiments, a recombinant attenuated derivative of a pathogenic Salmonella enterica serovar typhi cell is provided, (a) wherein one or more genes encoding subunits of a stg operon (Salmonella typhi Δstg) are inactivated or deleted resulting in a decrease of Stg adhesin/fimbriae production as compared to genes encoding a wild-type Stg operon (stgABCC′D), and/or (b) the cell comprises a nucleic acid encoding at least one of a gene encoding a subunit of a long polar fimbriae (Lpf) of S. enterica serovar Typhimurium protein. In certain embodiments, vaccines and compositions, and methods of use of the recombinant attenuated derivative of a pathogenic Salmonella enterica serovar typhi cell are provided. |
| FILED | Tuesday, May 01, 2018 |
| APPL NO | 15/968517 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0275 (20130101) A61K 2039/522 (20130101) Peptides C07K 14/255 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254720 | Cohen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Tufts Medical Center (Boston, Massachusetts); Trustees of Tufts College (Medford, Massachusetts); On Target Therapeutics LLC (Wellesley, Massachusetts) |
| ASSIGNEE(S) | On Target Therapeutics LLC (Wellesley, Massachusetts); Trustees of Tufts College (Medford, Massachusetts); Tufts Medical Center (Boston, Massachusetts) |
| INVENTOR(S) | Charles Cohen (Weston, Massachusetts); Krishna Kumar (Cambridge, Massachusetts); Jamie Raudensky Doyle (Newton, Massachusetts); Alan S. Kopin (Wellesley, Massachusetts) |
| ABSTRACT | The present application provides methods for preparing soluble lipidated ligand agents comprising a ligand entity and a lipid entity, and in some embodiments, provides relevant parameters of each of these components, thereby enabling appropriate selection of components to assemble active agents for any given target of interest. |
| FILED | Friday, January 11, 2019 |
| APPL NO | 16/245472 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/543 (20170801) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/4703 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) G01N 33/5023 (20130101) G01N 2405/00 (20130101) G01N 2440/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254732 | Bornholdt et al. |
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| FUNDED BY |
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| APPLICANT(S) | MAPP BIOPHARMACEUTICAL, INC. (San Diego, California); Albert Einstein College of Medicine (Bronx, New York); Adimab, LLC (Lebanon, New Hampshire) |
| ASSIGNEE(S) | MAPP BIOPHARMACEUTICAL, INC. (San Diego, California); ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York); ADIMAB, LLC (Lebanon, New Hampshire) |
| INVENTOR(S) | Zachary A. Bornholdt (Encinitas, California); Larry Zeitlin (San Diego, California); Kartik Chandran (Brooklyn, New York); Anna Wec (Lebanon, New Hampshire); Laura Walker (Norwich, Vermont) |
| ABSTRACT | Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus. |
| FILED | Tuesday, June 09, 2020 |
| APPL NO | 16/897001 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 2039/55 (20130101) A61K 2039/57 (20130101) A61K 2039/62 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) A61K 2039/6075 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254733 | Palese et al. |
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| FUNDED BY |
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| APPLICANT(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| ASSIGNEE(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| INVENTOR(S) | Peter Palese (New York, New York); Florian Krammer (New York, New York); Teddy John Wohlbold (New York, New York); Adolfo Garcia-Sastre (New York, New York) |
| ABSTRACT | Provided herein are antibodies that bind to neuraminidase (NA) of different strains of influenza B virus, host cells for producing such antibodies, and kits comprising such antibodies. Also provided herein are compositions comprising antibodies that bind to NA of different strains of influenza B virus and methods of using such antibodies to diagnose, prevent or treat influenza virus disease. |
| FILED | Friday, April 06, 2018 |
| APPL NO | 16/500628 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 2039/507 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) Peptides C07K 16/1018 (20130101) Original (OR) Class C07K 2317/33 (20130101) C07K 2317/34 (20130101) C07K 2317/52 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/94 (20130101) C07K 2317/565 (20130101) C07K 2317/732 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254735 | Isenberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland); Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Depar tment of Health and Human Services (Bethesda, Maryland); Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Jeffrey S. Isenberg (Mt. Lebanon, Pennsylvania); David D. Roberts (Bethesda, Maryland); William A. Frazier (Rock Hill, Missouri) |
| ABSTRACT | Provided herein are compositions for preventing, ameliorating, and/or reducing tissue ischemia and/or tissue damage due to ischemia, increasing blood vessel diameter, blood flow and tissue perfusion in the presence of vascular disease including peripheral vascular disease, atherosclerotic vascular disease, coronary artery disease, stroke and influencing other conditions, by suppressing CD47 and/or blocking TSP1 and/or CD47 activity or interaction. Influencing the interaction of CD47-TSP1 in blood vessels allows for control of blood vessel diameter and blood flow, and permits modification of blood pressure and cardiac function. Under conditions of decreased blood flow, for instance through injury or atherosclerosis, blocking TSP1-CD47 interaction allows blood vessels to dilate and increases blood flow, tissue perfusion and tissue survival. |
| FILED | Monday, June 17, 2019 |
| APPL NO | 16/443415 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 48/00 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/04 (20180101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/12 (20130101) B01J 21/063 (20130101) B01J 23/002 (20130101) B01J 23/30 (20130101) B01J 27/188 (20130101) B01J 37/0205 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/15 (20130101) B01J 2523/41 (20130101) B01J 2523/51 (20130101) B01J 2523/51 (20130101) B01J 2523/69 (20130101) B01J 2523/69 (20130101) B01J 2523/69 (20130101) Acyclic or Carbocyclic Compounds C07C 45/002 (20130101) C07C 45/52 (20130101) C07C 45/52 (20130101) C07C 47/22 (20130101) C07C 51/235 (20130101) C07C 51/252 (20130101) C07C 51/252 (20130101) C07C 57/04 (20130101) C07C 253/26 (20130101) Peptides C07K 7/06 (20130101) C07K 9/001 (20130101) C07K 14/78 (20130101) C07K 14/475 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6887 (20130101) G01N 33/6893 (20130101) G01N 2333/705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254781 | Langer et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Biocant-Center of Innovation and Biotechnology (Cantanhede, Portugal) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Biocant-Center of Innovation and Biotechnology (Cantanhede, Portugal) |
| INVENTOR(S) | Robert S. Langer (Newton, Massachusetts); Jeffrey M. Karp (Chestnut Hill, Massachusetts); Maria Jose Maio Nunes-Pereira (Lisbon, Portugal); Ben Ouyang (Toronto, Canada); Lino da Silva Ferreira (Coimbra, Portugal); Debanjan Sarkar (Williamsville, New York) |
| ABSTRACT | Among other things, the present disclosure provides compositions and methods for an elastomeric cross-linked polyester material. Such an elastomeric cross-linked polyester material, in some embodiments, comprises a plurality of polymeric units of the general formula (-A-B-)p, wherein p is an integer greater than 1; and a plurality of urethane cross-links each of which covalently links two polymeric units to one another, which two linked polymeric unit each had at least one free hydroxyl or amino group prior to formation of the crosslink. |
| FILED | Thursday, February 25, 2021 |
| APPL NO | 17/185528 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/703 (20130101) A61K 9/7084 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/14 (20130101) C08G 18/4236 (20130101) Original (OR) Class C08G 18/4238 (20130101) C08G 18/4283 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254918 | Sonnenburg et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); Novome Biotechnologies, Inc. (Daly City, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); Novome Biotechnolooies, Inc. (Daly City, California) |
| INVENTOR(S) | Justin L. Sonnenburg (Redwood City, California); Weston R. Whitaker (Daly City, California); Elizabeth Stanley (Portola Valley, California); William C. DeLoache (Oakland, California) |
| ABSTRACT | Compositions and methods are provided for modulating growth of a genetically modified bacterial cell present in a human organ, for modulating growth of a genetically modified bacterial cell in an organ (e.g., gut), for displacing at least a portion of a population of bacterial cells in an organ, and for facilitating gut colonization by a genetically modified bacterial cell. Also provided are genetically modified bacterial cells, e.g., cells that include a heterologous carbohydrate-utilization gene or gene set that provides for the ability to utilize as a carbon source a rare carbohydrate of interest that is utilized as a carbon source by less than 50% of bacterial cells present in a human microbiome. |
| FILED | Friday, November 06, 2020 |
| APPL NO | 17/091931 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/741 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/2402 (20130101) Original (OR) Class C12N 15/52 (20130101) C12N 15/74 (20130101) Enzymes C12Y 302/01178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254923 | Agar et al. |
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| FUNDED BY |
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| APPLICANT(S) | Brandeis University (Waltham, Massachusetts) |
| ASSIGNEE(S) | Brandeis University (Waltham, Massachusetts) |
| INVENTOR(S) | Jeffrey N. Agar (Newton, Massachusetts); Joseph Salisbury (Cranston, Rhode Island) |
| ABSTRACT | Described herein are compounds and methods for tethering proteins. For example, dimers of proteins, including SOD1 and DJ-1, are described, where the dimers are formed by the covalent bonding of a cysteine on the first monomer to a cysteine on the second monomer via a cyclic disulfide linker. The covalently attached dimers exhibit increased stabilization. |
| FILED | Friday, May 22, 2020 |
| APPL NO | 16/882035 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/095 (20130101) A61K 31/385 (20130101) Peptides C07K 19/00 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0089 (20130101) C12N 9/96 (20130101) Original (OR) Class Enzymes C12Y 115/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254933 | Gilbert et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Luke A Gilbert (San Francisco, California); Max Horlbeck (Oakland, California); Martin Kampmann (Oakland, California); Lei S Qi (Oakland, California); Jonathan S Weissman (San Francisco, California) |
| ABSTRACT | Methods, compositions, and kits are provided for CRISPR/Cas mediated transcriptional modulation. |
| FILED | Tuesday, July 14, 2015 |
| APPL NO | 15/326428 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) C12N 15/102 (20130101) C12N 15/1079 (20130101) Original (OR) Class C12N 15/1082 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254938 | Brigstock et al. |
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| FUNDED BY |
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| APPLICANT(S) | Research Institute at Nationwide Children's Hospital (Columbus, Ohio) |
| ASSIGNEE(S) | Research Institute at Nationwide Children's Hospital (Columbus, Ohio) |
| INVENTOR(S) | David Brigstock (Dublin, Ohio); Li Chen (Dublin, Ohio) |
| ABSTRACT | This disclosure provides pharmaceutical compositions and purified or isolated naturally occurring exosome products that have therapeutic use for treating an unmet medical need. The exosome compositions contain an effective amount of exosomes isolated from a body fluid of a non-diseased subject. The compositions are useful in the treatment of a variety of fibrotic diseases. |
| FILED | Tuesday, February 18, 2020 |
| APPL NO | 16/794066 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 31/00 (20130101) A61K 31/7088 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2310/141 (20130101) C12N 2320/32 (20130101) C12N 2330/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/52 (20130101) G01N 2800/7052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254939 | Flotte et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Terence Flotte (Holden, Massachusetts); Christian Mueller (Concord, Massachusetts); Phillip D. Zamore (Northborough, Massachusetts) |
| ABSTRACT | The invention relates to isolated nucleic acids and rAAV-based compositions, methods and kits useful for treating genetic diseases (e.g., alpha-1 antitrypsin deficiency). |
| FILED | Thursday, February 20, 2020 |
| APPL NO | 16/795757 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 35/12 (20130101) A61K 38/57 (20130101) A61K 48/005 (20130101) A61K 48/0058 (20130101) Peptides C07K 14/8125 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/67 (20130101) C12N 15/86 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/141 (20130101) C12N 2310/3519 (20130101) C12N 2320/31 (20130101) C12N 2750/14121 (20130101) C12N 2750/14132 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254988 | Yan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland); Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); Duke University (Durham, North Carolina) |
| INVENTOR(S) | Hai Yan (Chapel Hill, North Carolina); Darell Bigner (Mebane, North Carolina); Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Alan Meeker (Pikesville, Maryland); Ralph Hruban (Baltimore, Maryland); Nickolas Papadopoulos (Towson, Maryland); Luis Diaz (Ellicot City, Maryland); Yuchen Jiao (Baltimore, Maryland) |
| ABSTRACT | We determined the sequence of ATRX and DAXX in 447 cancers from various sites. We found mutations most commonly in pediatric glioblastoma multiformae (GBM) (11.1%), adult GBM (6.5%), oligodendrogliomas (7.7%) and medulloblastomas (1.5%); and showed that Alternative Lengthening of Telomeres (ALT), a telomerase-independent telomere maintenance mechanism found in cancers that have not activated telomerase, perfectly correlated with somatic mutations of either gene. In contrast, neuroblastomas, and adenocarcinomas of the ovary, breast, and pancreas were negative for mutations in ATRX and DAXX. Alterations in ATRX or DAXX define a specific molecular pathway that is closely associated with an alternative telomere maintenance function in human cancers. |
| FILED | Friday, May 25, 2018 |
| APPL NO | 15/989820 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255656 | So et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Peter T. C. So (Boston, Massachusetts); Zahid Yaqoob (Cambridge, Massachusetts); Dominika Lyzwa (Boston, Massachusetts); Vijay Singh (Arlington, Massachusetts); Dushan N. Wadduwage (Cambridge, Massachusetts) |
| ABSTRACT | Our high phase sensitivity wide-field phase cancellation interferometry system allows single-shot, label-free optical sensing of neural action potentials via imaging of optical path length changes. Single-shot sensing and monitoring of single neurons within a neural network should lead to a more comprehensive understanding neural network processing, which is beneficial for the advancement in the field of neuroscience as well as its biomedical applications and impact. Our system cancels the phase profile of the resting neuron from the phase profile of the spiking neuron, improving the sensitivity by two orders of magnitude. Using a detector with an extremely large well depth and an appropriately biased interferometer increases the sensitivity by another order of magnitude, yielding a measurement that is three orders of magnitude more sensitive than those possible with other microscopes. |
| FILED | Monday, January 04, 2021 |
| APPL NO | 17/140558 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02057 (20130101) Original (OR) Class G01B 9/02067 (20130101) G01B 9/02081 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0056 (20130101) G02B 21/361 (20130101) Computer Systems Based on Specific Computational Models G06N 3/0675 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255809 | Pamula et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Liquid Logic, Inc. (San Diego, California); Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Advanced Liquid Logic, Inc. (San Diego, California); Duke University (Durham, North Carolina) |
| INVENTOR(S) | Vamsee K. Pamula (Cary, North Carolina); Vijay Srinivasan (Cary, North Carolina); Michael G. Pollack (Durham, North Carolina); Richard B. Fair (Durham, North Carolina) |
| ABSTRACT | The present invention relates to droplet-based surface modification and washing. According to one embodiment, a method of splitting a droplet is provided, the method including providing a droplet microactuator including a droplet including one or more beads and immobilizing at least one of the one or more beads. The method further includes conducting one or more droplet operations to divide the droplet to yield a set of droplets including a droplet including the one or more immobilized beads and a droplet substantially lacking the one or more immobilized beads. |
| FILED | Tuesday, February 11, 2020 |
| APPL NO | 16/788187 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 13/0071 (20130101) B01F 13/0076 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/0268 (20130101) B01L 3/502715 (20130101) B01L 3/502723 (20130101) B01L 3/502761 (20130101) B01L 3/502784 (20130101) B01L 3/502792 (20130101) B01L 7/52 (20130101) B01L 7/525 (20130101) B01L 2200/027 (20130101) B01L 2200/0668 (20130101) B01L 2200/0673 (20130101) B01L 2200/0684 (20130101) B01L 2300/089 (20130101) B01L 2300/0654 (20130101) B01L 2300/0816 (20130101) B01L 2300/0861 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/1827 (20130101) B01L 2400/043 (20130101) B01L 2400/0406 (20130101) B01L 2400/0415 (20130101) B01L 2400/0424 (20130101) B01L 2400/0427 (20130101) B01L 2400/0436 (20130101) B01L 2400/0442 (20130101) B01L 2400/0448 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/26 (20130101) Original (OR) Class G01N 27/416 (20130101) G01N 27/447 (20130101) G01N 27/3271 (20130101) G01N 35/00029 (20130101) G01N 2035/00158 (20130101) G01N 2035/00237 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255814 | Karhanek et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Miloslav Karhanek (Santa Cruz, California); Chris David Webb (Watsonville, California); Senkei Umehara (Tokyo, Japan); Nader Pourmand (San Mateo, California) |
| ABSTRACT | Disclosed are methods and devices for biomolecular detection, comprising a nanopipette, exemplified as a hollow inert, non-biological structure with a conical tip opening of nanoscale dimensions, suitable for holding an electrolyte solution which may contain an analyte such as a protein biomolecule to be detected as it is passed through the tip opening. Biomolecules are detected by specific reaction with peptide ligands chemically immobilized in the vicinity of the tip. Analytes which bind to the ligands cause a detectible change in ionic current. A sensitive detection circuit, using a feedback amplifier circuit, and alternating voltages is further disclosed. Detection of IL-10 at a concentration of 4 ng/ml is also disclosed, as is detection of VEGF. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/588326 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/42 (20130101) Original (OR) Class G01N 27/4035 (20130101) G01N 33/48707 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255816 | Furtaw et al. |
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| FUNDED BY |
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| APPLICANT(S) | LI-COR, Inc. (Lincoln, Nebraska) |
| ASSIGNEE(S) | LI-COR, Inc. (Lincoln, Nebraska) |
| INVENTOR(S) | Michael D. Furtaw (Lincoln, Nebraska); Donald T. Lamb (Lincoln, Nebraska) |
| ABSTRACT | Devices, systems, and methods of using them are disclosed that position an end of a capillary electrophoresis tube within an internal tapered nozzle region of an inkjet print head or other microfluidic pump. The capillary electrophoresis tube can extend through an inlet of the microfluidic pump and leave space for a sheath liquid to enter the pump and mix with separated analytes eluted from the capillary electrophoresis tube. The small volume of mixed sheath liquid and analyte can then be jetted through the nozzle at a moving surface, either continuously or as discrete droplets. Relative positions on the surface can indicate separation distances of dispensed analytes. |
| FILED | Tuesday, April 28, 2020 |
| APPL NO | 16/860514 |
| ART UNIT | 1759 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44739 (20130101) Original (OR) Class G01N 27/44791 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255843 | Bass et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Joseph T. Bass (Winnetka, Illinois); Clara Bien Peek (Chicago, Illinois); Akihiko Taguchi (Chicago, Illinois); Mark Perelis (Evanston, Illinois); Biliana Marcheva (Evanston, Illinois) |
| ABSTRACT | The present invention relates to cells with altered cell cycle control. In particular, the present invention provides cells with altered cell cycle control and uses of such cells to identify metabolically active agents. |
| FILED | Wednesday, September 04, 2019 |
| APPL NO | 16/560597 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0658 (20130101) C12N 5/0676 (20130101) C12N 2510/00 (20130101) C12N 2510/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/507 (20130101) Original (OR) Class G01N 33/5005 (20130101) G01N 33/5008 (20130101) G01N 33/5061 (20130101) G01N 2333/62 (20130101) G01N 2800/042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255865 | Ganz et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Tomas Ganz (Los Angeles, California); Elizabeta Nemeth (Sherman Oaks, California); Leon Kautz (Lacroix-Falgarde, France); Chun-Ling Jung (Los Angeles, California) |
| ABSTRACT | Disclosed herein are antibodies that specifically bind human erythroferrone and assay methods for detecting and/or measuring human erythroferrone, analogs of human erythroferrone, and fragments thereof. Specifically, the methods comprising using an antibody as a capture reagent and an antibody as a detection reagent for detecting or measuring a detectable label of the at least one detection reagent bound to the erythroferrone polypeptide that is bound to the capture reagent. Further disclosed are the sequences of antibodies. |
| FILED | Monday, May 28, 2018 |
| APPL NO | 16/619140 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/22 (20130101) A61K 38/1816 (20130101) Peptides C07K 16/26 (20130101) C07K 2317/34 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255866 | Anderson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Rozalyn M. Anderson (Madison, Wisconsin); Dhanansayan Shanmuganayagam (Madison, Wisconsin); Ricki L. Colman (Cross Plains, Wisconsin); James Mukasa Ntambi (Fitchburg, Wisconsin); Mary J. Lindstrom (Madison, Wisconsin); Michael A. Polewski (Madison, Wisconsin); Maggie S. Burhans (Madison, Wisconsin) |
| ABSTRACT | Provided herein are reagents, methods and biochemical markers for identifying individuals with glucoregulatory dysfunction and providing therapeutic intervention for individuals identified as at risk for glucoregulatory dysfunction. Specifically provided herein are methods for identifying a subject with glucoregulatory dysfunction based on changes in fasting blood lipid concentrations including, inter alia, diacylglycerols. |
| FILED | Thursday, February 25, 2016 |
| APPL NO | 15/546526 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Original (OR) Class G01N 2800/04 (20130101) G01N 2800/042 (20130101) G01N 2800/044 (20130101) G01N 2800/50 (20130101) G01N 2800/52 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 40/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11256078 | Barentine et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Andrew Barentine (Cascade, Colorado); Joerg Bewersdorf (Guilford, Connecticut) |
| ABSTRACT | One aspect of the invention provides a method of continuously scanning with a localization microscope. The method includes: modifying a position of a sample relative to a field of view (FOV) of the localization microscope to capture a plurality of image frames of the sample, each captured image frame having a limited FOV; acquiring image frames with the localization microscope during at least one position modification; determining a set of localization position coordinates for at least one localizable object in the sample within at least one image frame of the plurality of image frames; determining one or more field of view (FOV) position coordinates for the at least one image frame; and modifying the set of localization position coordinates based on the one or more FOV position coordinates to produce a collection of coordinates covering a larger spatial region than the at least one image frame. |
| FILED | Monday, October 12, 2020 |
| APPL NO | 17/067875 |
| ART UNIT | 2484 — Recording and Compression |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11257255 | Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | Leica Microsystems CMS GmbH (Wetzlar, Germany) |
| ASSIGNEE(S) | Leica Microsystems CMS GmbH (Wetzlar, Germany) |
| INVENTOR(S) | Shih-Jong James Lee (Bellevue, Washington); Hideki Sasaki (Bellevue, Washington) |
| ABSTRACT | A computerized domain matching image conversion method for transportable imaging applications first performs a target domain A to source domain B matching converter training by computing means using domain B training images and at least one domain A image to generate an A to B domain matching converter. The method then applies the A to B domain matching converter to a domain A application image to generate its domain B matched application image. The method further applies a domain B imaging application analytics to the domain B matched application image to generate an imaging application output for the domain A application image. |
| FILED | Tuesday, December 03, 2019 |
| APPL NO | 16/702294 |
| ART UNIT | 2646 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/084 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 3/4046 (20130101) G06T 9/002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11257350 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Microsensor Labs, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | Microsensor Labs, LLC (Chicago, Illinois) |
| INVENTOR(S) | Peng Liu (Chicago, Illinois); Yang Liu (Chicago, Illinois); Jiapeng Huang (Louisville, Kentucky); Darius Cepulis (Forest Park, Illinois) |
| ABSTRACT | A system and method for opportunity-based hygiene monitoring and/or reminding is disclosed. Healthcare providers may have various opportunities to interact with a patient. As such, an opportunity-based focus in managing a healthcare environment may assist in assessing the various opportunities when interacting with the patient. For example, an opportunity-based analysis may be used for protocol compliance, such as compliance with hand hygiene protocols and/or PPE protocols. Further, infection analysis, patient care billing, staff locating, or workload analysis may be opportunity based in order to more efficiently manage the healthcare environment. |
| FILED | Monday, June 08, 2020 |
| APPL NO | 16/895435 |
| ART UNIT | 2685 — Selective Communication |
| CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 1/00 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/18 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10366 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/245 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11257584 | Buckler et al. |
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| FUNDED BY |
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| APPLICANT(S) | Elucid Bioimaging Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| INVENTOR(S) | Mary E. Buckler (Wenham, Massachusetts); Xiaonan Ma (South Hamilton, Massachusetts); Lawrence Martell (Wenham, Massachusetts); Andrew J. Buckler (Boston, Massachusetts) |
| ABSTRACT | Advanced reporting systems based on ontology development for quantitative imaging biomarkers, information modeling to integrate heterogeneous data types relevant to quantitative medical analysis, and a knowledge representation framework for their statistical validation. |
| FILED | Monday, August 13, 2018 |
| APPL NO | 16/102042 |
| ART UNIT | 2657 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 16/367 (20190101) G06F 16/3329 (20190101) G06F 40/30 (20200101) G06F 40/211 (20200101) G06F 40/242 (20200101) G06F 40/284 (20200101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 15/00 (20180101) G16H 30/20 (20180101) Original (OR) Class G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11253264 | Franklin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Prytime Medical Devices, Inc. (Boerne, Texas) |
| ASSIGNEE(S) | PRYTIME MEDICAL DEVICES, INC. (Boerne, Texas) |
| INVENTOR(S) | Curtis J. Franklin (Lakewood, Colorado); Todd J. Krummenacher (Lakewood, Colorado); Jeremy Reynolds (Lakewood, Colorado); David Spencer (Boerne, Texas); Luke William Fisher (Lakewood, Colorado) |
| ABSTRACT | An occlusion catheter system includes an inflation catheter member and an occlusion balloon. The proximal and distal balloon ends are connected to the inflation catheter between the proximal and distal catheter ends. A distal pressure sensor is attached to the inflation catheter member between the proximal balloon end and the atraumatic tip. An inflatable spine is connected to the inflation catheter. The proximal spine end is connected to the inflation catheter near the proximal balloon end and the distal spine end is connected to the inflation catheter near the distal balloon end. The occlusion balloon and the inflatable spine are configured to define blood flow channels with the internal surface and the external balloon surface when the occlusion catheter system is at least partially positioned in the vessel and the occlusion balloon and the inflatable spine are in a partially inflated configuration. |
| FILED | Monday, June 24, 2019 |
| APPL NO | 16/450067 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/12036 (20130101) A61B 17/12109 (20130101) A61B 17/12136 (20130101) Original (OR) Class A61B 2017/22051 (20130101) A61B 2017/22055 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/00 (20130101) A61M 25/02 (20130101) A61M 25/10 (20130101) A61M 25/0068 (20130101) A61M 25/104 (20130101) A61M 25/1002 (20130101) A61M 25/1011 (20130101) A61M 25/10184 (20131105) A61M 2025/0002 (20130101) A61M 2025/0003 (20130101) A61M 2025/024 (20130101) A61M 2025/028 (20130101) A61M 2025/0286 (20130101) A61M 2025/1052 (20130101) A61M 2025/1056 (20130101) A61M 2025/1061 (20130101) A61M 2025/1084 (20130101) A61M 2025/1088 (20130101) A61M 2025/1095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253268 | Burkart et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Joseph Thomas Burkart (Bloomfield, Indiana); Danielle E. Cafasso (Southern Pines, North Carolina); Robert Henry Hayford (Colorado Springs, Colorado); Huckelberry Finne (Norfolk, Virginia); Jose Ramirez Vargas (Clovis, New Mexico); Michael P. Abbott (Chesapeake, Virginia) |
| ABSTRACT | A junctional tourniquet apparatus and related methods of use. An exemplary tourniquet has an inverted cone shape, wherein a narrower end has a mushroom shaped base that is pressed against a compression target and a broader end has a plurality of pass-through slots for straps. Another exemplary tourniquet has a broad plate component and a handle component. The handle component has a mushroom shaped base on a first end and a handle on a second end. The handle component passes through the center of the plate component with threads that allow the handle component to compress a target by twisting the handle. |
| FILED | Friday, October 04, 2019 |
| APPL NO | 16/593389 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/1325 (20130101) Original (OR) Class A61B 17/1327 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253347 | Haupt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States, as Represented by the Secretary of the Army (Fort Detrick, Maryland); Government of the United States of America, as represented by the Secretary of the Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | The Government of the United States, as represented by the Secretary of the Army (Fort Detrick, Maryland); Government of the United States of America, as represented by the Secretary of the Commerce (Gaithersburg, Maryland) |
| INVENTOR(S) | Brett R. Haupt (Thurmont, Maryland); Matthew E. Staymates (Damascus, Maryland); Larry E. Bowen (Williamsport, Maryland); Mark M. Bailey (Gaithersburg, Maryland); Jaime B. Anderson (Hagerstown, Maryland) |
| ABSTRACT | A system for conducting inhalation studies includes an inhalation exposure chamber and an aerosol delivery line connected to the inhalation exposure chamber. The aerosol delivery line is configured to produce a bi-directional and symmetrical presentation of aerosol to the inhalation exposure chamber. A laminar flow element is configured to create an ante-chamber where complete and turbulent mixing of the aerosol occurs. A radial exhaust and the laminar flow element enable laminar flow of the aerosol through the inhalation exposure chamber. |
| FILED | Tuesday, February 07, 2017 |
| APPL NO | 16/076040 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Veterinary Instruments, Implements, Tools, or Methods A61D 7/04 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 15/009 (20130101) A61M 15/0065 (20130101) A61M 15/0086 (20130101) A61M 2205/50 (20130101) A61M 2206/11 (20130101) A61M 2206/16 (20130101) A61M 2250/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253483 | Tang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Yi Tang (San Gabriel, California); Zhen Gu (Los Angeles, California); Yunfeng Lu (Culver City, California); Ming Yan (Los Angeles, California); Anuradha Biswas (Los Angeles, California); Guoping Fan (Agoura Hills, California) |
| ABSTRACT | A method for intracellular delivery of single proteins or other cargo molecules by encapsulation within nanocapsules formed by interfacial polymerization of one or more types of monomers and selected protease cleavable cross-linkers is provided. The thin positively charged capsules are readily brought into the cytosol of target cells by endocytosis. The capsules are degraded by the action of endogenous proteases or co-delivered proteases on the cross-linkers releasing the functional cargo unaltered. The cross-linkers can be adapted to be cleavable by specific enzymes selected from available intracellular enzymes within the target cell or co-delivered or self-cleaving when the cargo itself is a protease. The nanocapsules produced by the methods have been shown to have long-term stability, high cell penetration capability, low toxicity and efficient protease-modulated specific degradability without affecting cargo protein function. |
| FILED | Monday, August 26, 2019 |
| APPL NO | 16/551535 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5138 (20130101) A61K 9/5169 (20130101) Original (OR) Class A61K 9/5192 (20130101) A61K 31/7088 (20130101) A61K 38/02 (20130101) A61K 41/0042 (20130101) A61K 47/58 (20170801) A61K 48/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253517 | O'Malley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
| ASSIGNEE(S) | BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
| INVENTOR(S) | Bert W. O'Malley (Houston, Texas); David Michael Lonard (Pearland, Texas); Jin Wang (Sugar Land, Texas); Jianming Xu (Bellaire, Texas); Jianwei Chen (Houston, Texas) |
| ABSTRACT | Small molecule regulators of steroid receptor coactivator (SRC) family proteins are provided, as well as methods for their use in treating or preventing SRC-related diseases. The SRC-related diseases can include cancer, metabolic disorders, human immunodeficiency virus, neurodegenerative disorders, and/or inflammatory diseases. Also provided are methods for regulating SRC family proteins in a cell. |
| FILED | Thursday, November 21, 2019 |
| APPL NO | 16/691195 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/426 (20130101) A61K 31/506 (20130101) Original (OR) Class A61K 31/4184 (20130101) A61K 31/4402 (20130101) Heterocyclic Compounds C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101) C07D 409/12 (20130101) C07D 413/12 (20130101) C07D 417/12 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) C07D 498/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253580 | Lyerly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Herbert K. Lyerly (Durham, North Carolina); Takuya Osada (Durham, North Carolina); Zachary C. Hartman (Durham, North Carolina) |
| ABSTRACT | Disclosed are compositions, methods, and kits for treating a cancer or pre-cancer. In particular, the invention generally relates to cancer vaccines as well as methods of delivering the vaccines. Combination treatments including the vaccines in combination with immunomodulatory agents are also contemplated. |
| FILED | Monday, January 09, 2017 |
| APPL NO | 16/068587 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 39/001106 (20180801) Original (OR) Class A61K 45/06 (20130101) A61K 2039/53 (20130101) A61K 2039/545 (20130101) A61K 2039/5158 (20130101) A61K 2039/55522 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253838 | Weston et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Numat Technologies Inc. (Skokie, Illinois) |
| ASSIGNEE(S) | NuMat Technologies Inc. (Skokie, Illinois) |
| INVENTOR(S) | Mitchell Hugh Weston (Chicago, Illinois); Edwin Alfonso Argueta Fajardo (Chicago, Illinois) |
| ABSTRACT | This invention relates to a Cu-BTC MOF which is water stable. The Cu-BTC MOF has been modified by substituting some of the BTC ligand (1,3,5, benzene tricarboxylic acid) with 5-aminoisophthalic acid (AIA). The resultant MOF retains at least 40% of its as synthesized surface area after exposure to liquid water at 60° C. for 6 hours. This is an unexpected result versus the MOF containing only the BTC ligand. This MOF can be used to abate contaminants such as ammonia in gas streams and especially air streams. |
| FILED | Friday, August 14, 2020 |
| APPL NO | 16/993803 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/58 (20130101) B01D 53/82 (20130101) B01D 53/8634 (20130101) B01D 2253/204 (20130101) B01D 2255/705 (20130101) B01D 2255/9207 (20130101) B01D 2257/406 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/226 (20130101) Original (OR) Class B01J 20/3085 (20130101) B01J 20/28016 (20130101) B01J 20/28019 (20130101) B01J 20/28038 (20130101) B01J 20/28045 (20130101) B01J 20/28066 (20130101) B01J 20/28073 (20130101) B01J 31/1691 (20130101) B01J 35/04 (20130101) B01J 35/08 (20130101) B01J 35/026 (20130101) B01J 35/1028 (20130101) B01J 37/04 (20130101) B01J 37/10 (20130101) B01J 2231/005 (20130101) B01J 2531/16 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253963 | Bafna et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Sudhir Bafna (Tucson, Arizona); David R. Smith (Green Valley, Arizona); Kohl Leger (Sahuarita, Arizona); Read L. Bryant (Tucson, Arizona) |
| ABSTRACT | A separable component assembly is disclosed. The separable component assembly can include a first component having a first interface portion. The separable component assembly can also include a second component coupled to the first component. The second component can have a second interface portion. In addition, the separable component assembly can include a seal disposed between the first and second interface portions. The seal can have a first interface surface associated with the first interface portion. The seal can also have a second interface surface in contact with the second interface portion. Additionally, the seal can have a peel initiator defining a discontinuity in a portion of the second interface surface. Upon separation of the first and second components from one another, the discontinuity can create a stress concentration in the second interface surface that initiates peeling of the second interface surface away from the second interface portion. |
| FILED | Monday, August 17, 2020 |
| APPL NO | 16/995737 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 19/04 (20130101) Original (OR) Class Jet-propulsion Plants F02K 9/343 (20130101) Pistons; Cylinders; Sealings F16J 15/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254092 | Xu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida) |
| INVENTOR(S) | Chengying Xu (Cary, North Carolina) |
| ABSTRACT | Composite materials are provided which may include one or more sheets of carbon fibers woven in orthogonal direction bundles; carbon nanotubes embedded within pores between the bundles; and a matrix material in which the one or more sheets and the carbon nanotubes are embedded. In one case, the carbon fibers lie substantially in an x-direction and a y-direction and the carbon nanotubes are oriented substantially in a z-direction, which is substantially perpendicular to the x- and y-directions. Methods for making the composite materials are also provided. |
| FILED | Monday, October 12, 2020 |
| APPL NO | 17/067925 |
| ART UNIT | 1789 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/00 (20130101) B32B 5/06 (20130101) B32B 5/08 (20130101) B32B 5/024 (20130101) B32B 5/26 (20130101) Original (OR) Class B32B 38/08 (20130101) B32B 2260/04 (20130101) B32B 2260/021 (20130101) B32B 2260/023 (20130101) B32B 2260/046 (20130101) B32B 2262/12 (20130101) B32B 2262/106 (20130101) B32B 2307/20 (20130101) B32B 2307/54 (20130101) B32B 2307/202 (20130101) B32B 2307/302 (20130101) B32B 2307/546 (20130101) B32B 2307/558 (20130101) B32B 2309/68 (20130101) B32B 2313/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254372 | Leonard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Polaris Industries Inc. (Medina, Minnesota) |
| ASSIGNEE(S) | Polaris Industries Inc. (Medina, Minnesota) |
| INVENTOR(S) | Joshua J. Leonard (North Branch, Minnesota); Richard Raymond Maki (North Branch, Minnesota); Eric Bjerketvedt (North Branch, Minnesota); Michael D. Schneider (Dalbo, Minnesota); Bradley Robert Morisch (Lindstrom, Minnesota); Brian D. Krosschell (Chisago City, Minnesota) |
| ABSTRACT | A vehicle is disclosed. The vehicle may include a base portion and a modular portion. The base portion may be a four wheel vehicle having an operator area with seating for at least two occupants in a side-by-side arrangement. The modular portion may be coupled to the base portion resulting in a six wheel vehicle. The wheels of the modular portion may be powered by an engine of the base portion. |
| FILED | Wednesday, February 24, 2021 |
| APPL NO | 17/184167 |
| ART UNIT | 3616 — Printing/Measuring and Testing |
| CURRENT CPC | Vehicle Suspension Arrangements B60G 3/20 (20130101) B60G 15/06 (20130101) B60G 15/067 (20130101) B60G 2200/144 (20130101) B60G 2202/24 (20130101) B60G 2206/011 (20130101) B60G 2206/0114 (20130101) B60G 2300/13 (20130101) Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 17/16 (20130101) Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for B60R 21/13 (20130101) Motor Vehicles; Trailers B62D 21/12 (20130101) B62D 21/14 (20130101) B62D 21/183 (20130101) B62D 33/063 (20130101) Original (OR) Class B62D 33/067 (20130101) B62D 33/077 (20130101) B62D 55/04 (20130101) B62D 61/10 (20130101) B62D 61/12 (20130101) B62D 63/025 (20130101) Couplings for Transmitting Rotation; Clutches; Brakes F16D 55/226 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254571 | Alston et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Jeffrey R. Alston (High Point, North Carolina); Jason T. Lamb (Huntersville, North Carolina) |
| ABSTRACT | A method for purifying a boron nitride nanotube feedstock is disclosed, including an initial step of mixing a boron nitride nanotube (BNNT) feedstock with a solvent to form an initial mixture. This BNNT feedstock is made up of hexagonal boron nitride (h-BN) particles and less than about 50 weight percent BNNTs on a dry basis. This initial mixture is then sonicated within a treatment vessel using an ultrasonic probe. At least a portion of the initial mixture is filtered out of the treatment vessel and across a nanoporous membrane at the same as the sonication. In this manner, the method provides a filtrate which is enriched in h-BN particles relative to the initial mixture and a retentate which is enriched in BNNTs relative to the initial mixture. |
| FILED | Friday, January 11, 2019 |
| APPL NO | 16/245821 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 11/0265 (20130101) B01D 71/36 (20130101) B01D 2325/02 (20130101) Non-metallic Elements; Compounds Thereof; C01B 21/0648 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254615 | Raj et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado) |
| INVENTOR(S) | Rishi Raj (Boulder, Colorado); Niriaina Andriamady (Boulder, Colorado); Thomas Clemenceau (Boulder, Colorado); Shikhar Jha (Pittsburgh, Pennsylvania) |
| ABSTRACT | Methods of forming structures including a substrate (e.g., ceramic) and an interface layer comprising a metal are disclosed. Structures and electrochemical cells and batteries are also disclosed. Exemplary methods include flash sintering of metal and ceramic materials. Various structures may be suitable for use as solid electrolytes in solid-state electrochemical cells, as well as for many other applications. |
| FILED | Wednesday, September 19, 2018 |
| APPL NO | 16/136063 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/64 (20130101) C04B 35/111 (20130101) C04B 35/486 (20130101) Original (OR) Class C04B 2235/66 (20130101) C04B 2235/3203 (20130101) C04B 2235/3227 (20130101) C04B 2235/3244 (20130101) C04B 2235/5436 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0562 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254732 | Bornholdt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MAPP BIOPHARMACEUTICAL, INC. (San Diego, California); Albert Einstein College of Medicine (Bronx, New York); Adimab, LLC (Lebanon, New Hampshire) |
| ASSIGNEE(S) | MAPP BIOPHARMACEUTICAL, INC. (San Diego, California); ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York); ADIMAB, LLC (Lebanon, New Hampshire) |
| INVENTOR(S) | Zachary A. Bornholdt (Encinitas, California); Larry Zeitlin (San Diego, California); Kartik Chandran (Brooklyn, New York); Anna Wec (Lebanon, New Hampshire); Laura Walker (Norwich, Vermont) |
| ABSTRACT | Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus. |
| FILED | Tuesday, June 09, 2020 |
| APPL NO | 16/897001 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 2039/55 (20130101) A61K 2039/57 (20130101) A61K 2039/62 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) A61K 2039/6075 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254941 | Yan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsale, Arizona) |
| INVENTOR(S) | Hao Yan (Chandler, Arizona); Yung Chang (Tempe, Arizona); Xiaowei Liu (Tempe, Arizona); Fei Zhang (Chandler, Arizona); Xiaodong Qi (Tempe, Arizona) |
| ABSTRACT | Certain embodiments provide RNA nanostructure (e.g., comprising one single-stranded RNA (ssRNA) molecule, wherein the RNA nanostructure comprises at least one paranemic cohesion crossover), as well as compositions and methods of use thereof. In certain embodiments, such RNA nanostructures are immuno-modulatory (e.g., immuno-stimulatory). |
| FILED | Thursday, August 30, 2018 |
| APPL NO | 16/642792 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/117 (20130101) Original (OR) Class C12N 2310/51 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254951 | Thess |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CureVac AG (Tübingen, Germany) |
| ASSIGNEE(S) | CureVac AG (Tübingen, Germany) |
| INVENTOR(S) | Andreas Thess (Kusterdingen, Germany) |
| ABSTRACT | The invention relates to an artificial nucleic acid molecule comprising at least one open reading frame and at least one 3′-untranslated region element (3′-UTR) element comprising a nucleic acid sequence which is derived from the 3′-UTR of a ribosomal protein gene. The invention further relates to the use of such an artificial nucleic acid molecule in gene therapy and/or genetic vaccination. Furthermore, the invention relates to the use of a 3′-UTR element comprising a nucleic acid sequence which is derived from the 3′-UTR of a ribosomal protein gene for enhancing, stabilizing and/or prolonging protein expression from a nucleic acid sequence comprising such 3′-UTR element. |
| FILED | Monday, July 09, 2018 |
| APPL NO | 16/030018 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/67 (20130101) C12N 15/85 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254972 | Minev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Dionis Minev (Cambridge, Massachusetts); Christopher Wintersinger (Jamaica Plain, Massachusetts); William M. Shih (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein, in some embodiments, are methods, compositions and kits for controlling nucleation and assembly of molecular nanostructures, microstructures and macrostructures. |
| FILED | Wednesday, August 02, 2017 |
| APPL NO | 16/322787 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 21/00 (20130101) C07H 21/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6811 (20130101) C12Q 1/6837 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255207 | Peters |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Christopher J. Peters (Los Lunas, New Mexico) |
| ABSTRACT | Aspects of the disclosure are directed to a seal comprising: a shoe, and at least two beams coupled to the shoe, where a first width associated with the beams exceeds a second width associated with the shoe in a reference direction. Aspects of the disclosure are directed to an engine comprising: a compressor section, a turbine section, and a floating, non-contact seal that includes: a shoe, and at least two beams coupled to the shoe, where the beams extend past an edge of a flowpath surface associated with the shoe in a reference direction. |
| FILED | Friday, August 23, 2019 |
| APPL NO | 16/549663 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/02 (20130101) F01D 9/02 (20130101) F01D 11/025 (20130101) Original (OR) Class Non-positive-displacement Pumps F04D 29/164 (20130101) F04D 29/526 (20130101) Pistons; Cylinders; Sealings F16J 15/442 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255379 | Baskin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sikorsky Aircraft Corporation (Stratford, Connecticut) |
| ASSIGNEE(S) | SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut) |
| INVENTOR(S) | Bryan Kenneth Baskin (Arlington, Texas); James Orbon (New Haven, Connecticut); Stephen V. Poulin (Milford, Connecticut) |
| ABSTRACT | A spherical bearing which extends from and connects to a deformable component includes an outer member and an inner member. The inner member is pivotable relative to the outer member about an axis. The inner member has an opening formed therein that defines a plurality of coplanar contact surfaces shaped to accommodate and contact the component. The plurality of contact surfaces are movable to accommodate deformation of the component positioned within the opening. |
| FILED | Wednesday, July 19, 2017 |
| APPL NO | 16/328671 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/12 (20130101) B64C 27/32 (20130101) B64C 27/605 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 23/043 (20130101) F16C 23/046 (20130101) F16C 25/04 (20130101) Original (OR) Class F16C 27/02 (20130101) F16C 2326/43 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255546 | Dziech et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Aaron Michael Dziech (Crittenden, Kentucky); Megan Elizabeth Scheitlin (Cincinnati, Ohio) |
| ABSTRACT | Combustor assemblies and methods for assembling combustor assemblies are provided. For example, a combustor assembly comprises an annular inner liner and an annular outer linear, each extending generally along an axial direction. The outer liner includes an outer flange extending forward from its upstream end. The combustor assembly also comprises a combustor dome extending between an inner liner upstream end and the outer liner upstream end and including an inner flange extending forward from a radially outermost end of the combustor dome. The inner liner, outer liner, and combustor dome define a combustion chamber therebetween, and the combustor dome and a portion of the outer liner together define an annular cavity of the combustion chamber. The inner and outer flanges define an airflow opening therebetween, and a chute member is positioned within the airflow opening to define an air chute for providing a flow of air to the annular cavity. |
| FILED | Tuesday, December 03, 2019 |
| APPL NO | 16/701226 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 3/007 (20130101) F23R 3/10 (20130101) F23R 3/58 (20130101) Original (OR) Class F23R 3/60 (20130101) F23R 2900/00015 (20130101) F23R 2900/00017 (20130101) F23R 2900/03042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255786 | Ancona et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Mario Ancona (Alexandria, Virginia); Hieu Bui (Alexandria, Virginia) |
| ABSTRACT | The stiffness and topology of ultra-small circular DNAs and DNA/peptide hybrids are exploited to create a transducer of enzyme activity with low error rates. The modularity and flexibility of the concept are illustrated by demonstrating various transducers that respond to either specific restriction endonucleases or to specific proteases. In all cases the output is a DNA oligo signal that, as we show, can readily be converted directly to an optical readout, or can serve as input for further processing, for example, using DNA logic or amplification. By exploiting the DNA hairpin (or stem-loop) structure and the phenomenon of strand displacement, an enzyme signal is converted into a DNA signal, in the manner of a transducer. This is valuable because a DNA signal can be readily amplified, combined, and processed as information. |
| FILED | Wednesday, June 16, 2021 |
| APPL NO | 17/348824 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/005 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) Original (OR) Class G01N 33/52 (20130101) G01N 33/542 (20130101) G01N 2021/6432 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255794 | Beshay et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTELLIGENT OPTICAL SYSTEMS, INC. (Torrance, California) |
| ASSIGNEE(S) | Intelligent Optical Systems, Inc. (Torrance, California); United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Manal Beshay (Rancho Palos Verdes, California); Janet L. Jensen (Aberdeen, Maryland); James M. Cress (Aberdeen, Maryland) |
| ABSTRACT | Disclosed are systems and methods for the robust passive detection of airborne toxins using a colorimetric sensor coating onto a optically transparent substrate. In certain embodiments, the substrate is affixed to an adhesive material (tape). In certain embodiments, the sensor and substrate are transparent. In various embodiments, multiple sensors are coated onto selected substrate for the simultaneous detection of multiple toxins. In various embodiments, the sensed or detected toxins include a number of chemical warfare agents and toxic industrial chemicals. In various implementations, the tape is affixed to a remote surface, which may be visually monitored by a camera directly by focusing the camera on the tape or may be affixed to a camera lens by an adhesive backing, such that colorimetric sensor changes may be observed through the lens itself. Sensor claddings consist of optical grade polymers immobilized with colorimetric and/or fluorescent indicators that undergo optical changes upon exposure to their target analyte. Typical substrate cross-linked polymers are urethane acrylate polymer based, co-polymerized with silicone backbone such as dimethyl siloxane, which in general is chemically inert, yet leaves the polymer with the large free-volume necessary for rapid target diffusion. The polymer is cured after immobilization with target indicator mixture, and simultaneously cross-linked by UV light or heat. |
| FILED | Friday, February 22, 2019 |
| APPL NO | 16/283712 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/783 (20130101) Original (OR) Class G01N 33/0057 (20130101) G01N 2021/7756 (20130101) G01N 2021/7759 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255830 | Feinstein et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Research Foundation of the City University of New York (New York, New York) |
| ASSIGNEE(S) | Research Foundation of the City University of New York (New York, New York) |
| INVENTOR(S) | Paul Feinstein (New York, New York); Charlotte D'Hulst (Brooklyn, New York) |
| ABSTRACT | A biosensor for detecting trinitrotoluene (TNT) is disclosed. The biosensor has cells, such as olfactory sensory neurons (or cilia derived therefrom), that preferentially express a TNT-responsive odorant receptor protein. |
| FILED | Tuesday, January 02, 2018 |
| APPL NO | 16/474814 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0278 (20130101) A01K 2217/052 (20130101) A01K 2227/105 (20130101) A01K 2267/0393 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/062 (20130101) C12N 15/63 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 31/22 (20130101) Original (OR) Class G01N 33/566 (20130101) G01N 33/5058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255922 | Yeh |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Hen-Geul Yeh (Cypress, California) |
| ABSTRACT | Real-time detection of high-impedance faults in a distribution circuit is described. The real-time detection of high-impedance faults includes two steps. First, adaptive soft denoising is employed to perform a filtering process on a healthy dataset, and to determine a threshold. This reduces the rate of false alarms. Second, faulty datasets are prefiltered via adaptive soft denoising, then the denoised signals are processed via discrete wavelet transform to perform high-impedance fault detection using the threshold. |
| FILED | Wednesday, August 19, 2020 |
| APPL NO | 16/996960 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 19/1659 (20130101) G01R 31/58 (20200101) Original (OR) Class Emergency Protective Circuit Arrangements H02H 1/0007 (20130101) H02H 7/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255929 | Lemay |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | QUINC.TECH INC. (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lee Lemay (San Diego, California) |
| ABSTRACT | Aspects of the present disclosure generally pertain to a magnetic field sensor with flex coupling structures. Aspects of the present disclosure are more specifically directed toward Nanoscale Superconducting Quantum Interference Devices (nanoSQUIDs) with very low white flux noise characteristics can be fashioned into very sensitive magnetic field sensors by using external structures to increase the amount of flux that passes through the nanoSQUID aperture. One such structure is a superconducting coupling loop that shares part of a circuit with the nanoSQUID, and couples flux into the nanoSQUID primarily through kinetic inductance rather than geometric inductance. |
| FILED | Wednesday, March 27, 2019 |
| APPL NO | 16/367230 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/0356 (20130101) G01R 33/0358 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/223 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11256031 | Lipson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Michal Lipson (New York, New York); You-Chia Chang (New York, New York); Samantha P. Roberts (Ithica, New York); Brian Stern (New York, New York); Utsav D. Dave (New York, New York) |
| ABSTRACT | Light recycling within a waveguide is achieved by mode conversion instead of resonance. A structure is provided in in which light makes multiple passes through the same waveguide by converting the mode to a different mode after each pass and rerouting the light back into the same waveguide. The structure includes a bus waveguide and at least one mode converter device disposed at or adjacent each of two opposing ends of the bus waveguide, wherein each mode converter devices is configured to receive light having a receiving mode along a first direction and to cause light having a different mode from the receiving mode to propagate in a second direction opposite the first direction. |
| FILED | Tuesday, June 26, 2018 |
| APPL NO | 16/626616 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/14 (20130101) Original (OR) Class G02B 6/0046 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/01 (20130101) G02F 1/295 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11256813 | Noel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Patrick Noel (Waymart, Pennsylvania); Brian Medwetz (Mountain Top, Pennsylvania); Donna Askew (West Pittston, Pennsylvania); John Kostiak, Jr. (Avoca, Pennsylvania) |
| ABSTRACT | A profile can be created for a system indicating various attributes of the system. Based on these attributes, a set of security vulnerabilities can be identified. A mitigation function list can be determined that addresses at least part of the set of security vulnerabilities. The mitigation function list can be performed upon the system to mitigate at least part of the set of security vulnerabilities. A report can be generated identifying how the security vulnerabilities were mitigated and/or security vulnerabilities that still exist in the system. |
| FILED | Monday, January 28, 2019 |
| APPL NO | 16/259088 |
| ART UNIT | 2437 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/9035 (20190101) G06F 21/554 (20130101) G06F 21/577 (20130101) Original (OR) Class G06F 2221/034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11257184 | Rehling |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | John F. Rehling (Encinitas, California) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | John F. Rehling (Encinitas, California) |
| ABSTRACT | In the described examples, a compiled image scaler includes a set of machine executable instructions that generate a scaled image that is a scaled version of a source image with integer and bitwise operations. The compiled image scaler employs filtering to blend colors of adjacent pixels in the source image to generate the scaled image, and each filtering operation concurrently scales three color channels of a pixel in the source image. |
| FILED | Wednesday, February 21, 2018 |
| APPL NO | 15/901486 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 1/20 (20130101) G06T 3/4023 (20130101) Original (OR) Class G06T 5/002 (20130101) G06T 5/20 (20130101) G06T 7/90 (20170101) G06T 2207/10024 (20130101) G06T 2207/20192 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11257281 | Lilley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cesium GS, Inc. (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | CESIUM GS, INC. (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Ian Lilley (Philadelphia, Pennsylvania); Sean Lilley (Philadelphia, Pennsylvania); Patrick Cozzi (Drexel Hill, Pennsylvania) |
| ABSTRACT | Systems, methods, devices, and non-transitory media of various embodiments enable rendering of a time-dynamic (4D) volume dataset. Various embodiments may provide a method for responsive and high quality rendering of time-dynamic hierarchical level-of-detail voxel datasets. Various embodiments may provide a prioritization system that balances visual quality and temporal responsiveness even with slow network or filesystem speeds. Various embodiments may provide a compact and efficient storage format for time-dynamic and mixed-resolution voxel rendering on a graphics processing unit (GPU). |
| FILED | Friday, July 09, 2021 |
| APPL NO | 17/372344 |
| ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 15/04 (20130101) G06T 15/005 (20130101) G06T 15/08 (20130101) Original (OR) Class G06T 15/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11257595 | Tolliver et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Laura Catherine Tolliver (Charleston, South Carolina); Kevin Paul Votapka (Charleston, South Carolina); Scott Christopher Batson (Hanahan, South Carolina); Bruce James Billian (Mt. Pleasant, South Carolina); Tony Donald Stafford (Summerville, South Carolina); Kaitlyn Rebecca Bub (Mt. Pleasant, South Carolina); Hunter Joseph Smith (Charleston, South Carolina); Lucas Duane Powell (Charleston, South Carolina); Wesley Jamel Jones (North Charleston, South Carolina); Brandon Scott Lood (Hanahan, South Carolina); Joshua James Murphy (Summerville, South Carolina); Kevin Joseph Pinzhoffer (Daniel Island, South Carolina); Christopher Stephen Williams (Mt. Pleasant, South Carolina); Peyton Cavaroc (Charleston, South Carolina); Alicia Hilton (North Charleston, South Carolina) |
| ABSTRACT | A low-power platform senses an environment around the platform. The platform includes sensor interfaces, a multiplexer, a dual port memory, a processor, and a radio. The similar sensor interfaces are for attaching environmental sensors. The multiplexer combines the environmental data from the attached environmental sensors into a single stream. The dual port memory temporarily stores the stream. The processor intermittently retrieves the stream from the dual port memory. The radio forwards the stream toward a central system. Each interface includes a mechanical interlock for attaching a respective environmental sensor and an electrical interlock for detecting whether the mechanical interlock engages the environmental sensor. Each interface transfers peripheral power and environmental data for the respective environmental sensor. The platform also includes a battery for supplying the peripheral power to the environmental sensors, and for supplying internal power for the interfaces, the multiplexer, the dual port memory, the processor, and the radio. |
| FILED | Tuesday, November 26, 2019 |
| APPL NO | 16/696252 |
| ART UNIT | 2474 — Multiplex and VoIP |
| CURRENT CPC | Information and Communication Technology Specially Adapted for the Internet of Things [IOT] G16Y 20/10 (20200101) Original (OR) Class G16Y 40/10 (20200101) G16Y 40/35 (20200101) Wireless Communication Networks H04W 84/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11257746 | Vaisband et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Boris Vaisband (Los Angeles, California); Subramanian S. Iyer (Los Angeles, California); Adeel A. Bajwa (Los Angeles, California) |
| ABSTRACT | A silicon interconnect fabric includes: (1) a substrate having a front side and a back side; (2) a front side patterned metal layer on the front side of the substrate; (3) a back side patterned metal layer on the back side of the substrate; (4) multiple conductive vias extending through the substrate and connecting the front side patterned metal layer and the back side patterned metal layer; and (5) multiple conductive posts connected to the back side patterned metal layer. |
| FILED | Thursday, November 01, 2018 |
| APPL NO | 16/760845 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/147 (20130101) H01L 23/473 (20130101) H01L 23/49811 (20130101) H01L 23/49827 (20130101) Original (OR) Class H01L 23/49866 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11257866 | BrightSky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Matthew J. BrightSky (Armonk, New York); Cyril Cabral, Jr. (Yorktown Heights, New York); Kenneth P. Rodbell (Sandy Hook, Connecticut) |
| ABSTRACT | A reactive material erasure element comprising a reactive material is located between PCM cells and is in close proximity to the PCM cells. The reaction of the reactive material is trigger by a current applied by a bottom electrode which has a small contact area with the reactive material erasure element, thereby providing a high current density in the reactive material erasure element to ignite the reaction of the reactive material. Due to the close proximity of the PCM cells and the reactive material erasure element, the heat generated from the reaction of the reactive material can be effectively directed to the PCM cells to cause phase transformation of phase change material elements in the PCM cells, which in turn erases data stored in the PCM cells. |
| FILED | Friday, November 22, 2019 |
| APPL NO | 16/692586 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 13/003 (20130101) G11C 13/0004 (20130101) G11C 13/0059 (20130101) G11C 13/0069 (20130101) G11C 13/0097 (20130101) G11C 2013/008 (20130101) G11C 2213/50 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/2463 (20130101) Original (OR) Class H01L 45/06 (20130101) H01L 45/16 (20130101) H01L 45/143 (20130101) H01L 45/144 (20130101) H01L 45/1233 (20130101) H01L 45/1286 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11258062 | Atwater et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Government, as represented by the Secretary of the Army (Aberdeen Proving Ground, Maryland) |
| ASSIGNEE(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Terrill B. Atwater (Bel Air, Maryland); Matthew A. Limpert (Kennett Square, Pennsylvania); Ashley L. Ruth (Bel Air, Maryland); Paula C. Latorre (Bel Air, Maryland) |
| ABSTRACT | A process for preparing a cathode material of the form LiaMn1-x-y-zFexCoyNizO2-dCld is provided. In addition, a LiaMn1-x-y-zFexCoyNizO2-dCld cathode material for electrochemical systems is provided. Furthermore, a lithium or lithium-ion rechargeable electrochemical cell is provided, incorporating the LiaMn1-x-y-zFexCoyNizO2-dCld cathode material in a positive electrode. |
| FILED | Wednesday, July 31, 2019 |
| APPL NO | 16/527855 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 53/006 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/50 (20130101) C01P 2002/72 (20130101) C01P 2002/85 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/505 (20130101) Original (OR) Class H01M 4/525 (20130101) H01M 10/0525 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11258159 | Timberlake |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Garrett L. Timberlake (Virginia Beach, Virginia) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Garrett L. Timberlake (Virginia Beach, Virginia) |
| ABSTRACT | A pedestal is provided for mounting a portable antenna onto a platform. The pedestal includes a ring, a base, a horn and a prong composed of three-dimensionally printable composite resin. The ring attaches to the platform. The base inserts into the ring and includes an outer tube having a pair of axially distributed outer holes. The horn includes an inner tube for insertion into the outer tube and an inverted pyramid that connects to the inner tube. The inner tube includes at least three axially distributed inner holes. The prong has two probes that insert into the outer holes and two of the inner holes to secure the horn to the base. |
| FILED | Monday, April 20, 2020 |
| APPL NO | 16/853654 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/00 (20141201) B33Y 80/00 (20141201) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 163/00 (20130101) Antennas, i.e Radio Aerials H01Q 1/12 (20130101) H01Q 1/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11258210 | Penry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Combat Capabilities Development Command, Chemical Biological Center (Apg, Maryland) |
| ASSIGNEE(S) | Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Jeremy D Penry (Aberdeen Proving Ground, Maryland); Richard D Wallace, III (Bel Air, Maryland); Jeffrey S Loftus (Sykesville, Maryland) |
| ABSTRACT | A cable system includes a sensor connection segment (SCS), a computer connection segment (CCS), and a radio connection segment (RCS). The SCS includes a printed circuit board assembly (PCBA) and a sensor connection cable for connecting the PCBA to a host sensor system. The PCBA includes hardware and software for providing an embedded web server as part of the cable system. The PCBA can send sensor data over a radio network or receive firmware and calibration updates using the RCS and the CCS, respectively. |
| FILED | Wednesday, September 11, 2019 |
| APPL NO | 16/567757 |
| ART UNIT | 2443 — Computer Networks |
| CURRENT CPC | Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 12/53 (20130101) H01R 13/6683 (20130101) Original (OR) Class H01R 13/6691 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/02 (20130101) H04L 67/12 (20130101) H04L 67/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11258377 | Fiordilino et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Joseph A. Fiordilino (Pittsburgh, Pennsylvania); Subrata Sanyal (Eastvale, California) |
| ABSTRACT | The present invention relates to a device which can measure, induce, and correct perturbations acting on an electromagnetic (EM) propagation source. Piezoelectric transducers are used to measure and control perturbations within a system to improve operation of an EM source. Perturbation measurements can be used to determine the environmental and system impacts on the EM source. Moreover, measurements can be used to correct or nullify perturbations applied to the EM source, through active or passive means. |
| FILED | Wednesday, September 19, 2018 |
| APPL NO | 16/135064 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Springs; Shock-absorbers; Means for Damping Vibration F16F 15/005 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 7/00 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/00 (20130101) G01P 15/097 (20130101) Optical Elements, Systems, or Apparatus G02B 7/008 (20130101) G02B 27/646 (20130101) Electric Machines Not Otherwise Provided for H02N 2/005 (20130101) H02N 2/0075 (20130101) Original (OR) Class H02N 2/181 (20130101) Pictorial Communication, e.g Television H04N 1/047 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11258423 | Rinaldi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Matteo Rinaldi (Boston, Massachusetts); Guofeng Chen (Fremont, California) |
| ABSTRACT | A resonator system is provided in which a combined overtone resonator device is excited with a two-dimensional mode of mechanical vibration in a cross sectional plane of a piezoelectric plate in response to an alternating voltage applied through an interdigitated electrode. The cross sectional plane extends along the width direction and the thickness direction, and the two-dimensional mode of mechanical vibration is a two-dimensional combined overtone mode of second and third order asymmetrical Lamb-wave overtones. |
| FILED | Tuesday, October 13, 2020 |
| APPL NO | 17/069331 |
| ART UNIT | 2843 — Electrical Circuits and Systems |
| CURRENT CPC | Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/462 (20130101) H03H 9/02228 (20130101) Original (OR) Class H03H 9/02338 (20130101) H03H 2009/02527 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11258471 | Boghrat et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PHYSICAL OPTICS CORPORATION (Torrance, California) |
| ASSIGNEE(S) | PHYSICAL OPTICS CORPORATION (Torrance, California) |
| INVENTOR(S) | Pedram Boghrat (Torrance, California); Thomas C. Forrester (Torrance, California); Tomasz Jannson (Torrance, California); Andrew Kostrzewski (Garden Grove, California); Robert Anthony Kunc (Rancho Palos Verdes, California); Anthony Shangchi Lai (La Crescenta, California); Kang S. Lee (Tustin, California); John Matthews (Torrance, California); Ranjit Dinkar Pradhan (Rancho Palos Verdes, California); Robert Everett Stephens (Torrance, California) |
| ABSTRACT | An integrative software radio embodies a single multi-radio device including functionalities that are a superset of a plurality of individual discrete radio devices includes a radio frequency transmitter that integrates transmission capabilities of a plurality of discrete transmitters such that the radio frequency transmitter is configured to generate a first amalgamated waveform that is a combination of individual waveforms, each individual waveform corresponding to the transmission capabilities of its respective one of the plurality of discrete transmitters, wherein the transmission capabilities each of the plurality of discrete transmitters comprise operating characteristics different from one or more of the other discrete transmitters, wherein a waveform of a discrete transmitter comprises an adjustable electromagnetic wavefront and a proprietary waveform generation component; and a mission module communicatively coupled to the plurality of discrete transmitters and configured to alter the wavefront of at least one of the plurality of discrete transmitters to reduce interference among the at least one of the plurality of discrete transmitters without adjusting the proprietary waveform generation component. |
| FILED | Friday, December 13, 2019 |
| APPL NO | 16/714053 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Amplifiers H03F 1/3247 (20130101) H03F 3/195 (20130101) H03F 3/245 (20130101) H03F 2200/321 (20130101) H03F 2200/451 (20130101) Transmission H04B 1/0475 (20130101) Original (OR) Class H04B 2001/045 (20130101) H04B 2001/0425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11259402 | Heckman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Emily M. Heckman (Dayton, Ohio); Jeffrey P. Massman (Centerville, Ohio); Roberto S. Aga (Beavercreek, Ohio); Fahima Ouchen (Beavercreek, Ohio) |
| ABSTRACT | A printed circuit board (PCB) comprises two or more PCB layers comprising of a dielectric core and conductive cladding on adjoining surfaces; one or more DC lines embedded in one or more layers of the two or more PCB layers; one or more RF signal lines embedded in one or more layers of the two or more PCB layers; wherein the one or more DC lines crosses over/under at least one of the RF signal lines to form at least one crossover, wherein the at least one crossover is no thicker than the PCB layer in which it is situated. The printed circuit board of claim 1, further comprising two or more generally parallel DC lines which converge to form a stack of superposed parallel DC lines where the two or more DC lines cross over the one or more RF signal lines. |
| FILED | Tuesday, September 08, 2020 |
| APPL NO | 17/014054 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0228 (20130101) Original (OR) Class H05K 3/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11253820 | Bhave et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); All American Lithium LLC (Brawley, California) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); All American Lithium LLC (El Paso, Texas) |
| INVENTOR(S) | Ramesh R. Bhave (Knoxville, Tennessee); Stephen Harrison (Benicia, California); Bruce A. Moyer (Oak Ridge, Tennessee); M. Parans Paranthaman (Knoxville, Tennessee) |
| ABSTRACT | A lithium extraction composite comprising: (i) a porous support and (ii) particles of a lithium-selective sorbent material coated on at least one surface of the support, wherein the support has a planar membrane, fiber (or rod), or tubular shape. A method for extracting and recovering a lithium salt from an aqueous solution by use of the above-described composition is also described, the method comprising (a) flowing the aqueous source solution through a first zone or over a first surface of the lithium extraction composite to result in selective lithium intercalation in the lithium-selective sorbent material in the first zone or first surface; and (b) simultaneously recovering lithium salt extracted in step (a) from said lithium-selective sorbent material by flowing an aqueous stripping solution through a second zone or over a second surface of the lithium extraction composite in which lithium ions from the first zone or first surface diffuse. |
| FILED | Friday, March 08, 2019 |
| APPL NO | 16/296943 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 69/04 (20130101) B01D 69/08 (20130101) B01D 69/10 (20130101) B01D 69/12 (20130101) Original (OR) Class B01D 71/021 (20130101) B01D 71/024 (20130101) B01D 71/34 (20130101) B01D 2257/204 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 26/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253837 | Britt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | David Britt (El Cerrito, California); Daniel Sun (Sion, Switzerland); Wendy Queen (Grimisuat, Switzerland) |
| ABSTRACT | A composition of matter for selective binding of at least one heavy metal comprising at least one porous metal-organic framework (MOF) with unsaturated coordination sites, at least one organic ligand functionalized with at least one functional group tailored to bind to the at least one MOF, and at least one separate functional group tailored to bind to the at least one heavy metal. |
| FILED | Monday, October 15, 2018 |
| APPL NO | 16/160629 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/226 (20130101) Original (OR) Class B01J 20/28033 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/281 (20130101) C02F 1/285 (20130101) C02F 2101/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253908 | Lim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Yong Chae Lim (Oak Ridge, Tennessee); Zhili Feng (Oak Ridge, Tennessee); Jian Chen (Oak Ridge, Tennessee); Xin Sun (Oak Ridge, Tennessee); Richard W. Davies (Oak Ridge, Tennessee) |
| ABSTRACT | A method for joining dissimilar materials is provided. The method includes a solid-state joining process in which a rivet is plunged into a predrilled hole in a top workpiece. When the rivet contacts the bottom workpiece, ultrasonic vibration by oscillatory motion of a sonotrode, such as horizontal, vertical, or rotational motion, creates frictional heat at the interface between the rivet and the lower workpiece. With the aid of frictional heat and axial compression, metallurgical bonding is achieved at the interface between the rivet and the bottom sheet, while being below the melting temperature of the bottom workpiece. The sonotrode is retracted while the rivet remains. |
| FILED | Monday, April 27, 2020 |
| APPL NO | 16/858770 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Forging; Hammering; Pressing Metal; Riveting; Forge Furnaces B21J 15/027 (20130101) Original (OR) Class Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 65/645 (20130101) B29C 66/1122 (20130101) B29C 66/7212 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253958 | Rutkowski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Treau, Inc. (San Francisco, California) |
| ASSIGNEE(S) | TREAU, INC. (San Francisco, California) |
| INVENTOR(S) | Adam Rutkowski (San Francisco, California); Grace Li (San Francisco, California); Peter Sturt Lynn (Alameda, California); Adrien Benusiglio (San Francisco, California); Vincent Domenic Romanin (San Francisco, California); Jason Stein Wexler (San Francisco, California); Bataung Mohapi (Berkeley, California) |
| ABSTRACT | A method of manufacturing a heat exchanger array that includes stacking a plurality of heat exchanger units in an aligned configuration with respective first ports of the plurality of heat exchanger units aligned. The method can further include generating heat in the first coupling elements at the same time and at a temperature sufficient to generate a first plurality of respective couplings between adjacent sheets of adjacent heat exchanger units about adjacent first ports and without a coupling being generated between the first and second sheets of a given heat exchanger unit. |
| FILED | Tuesday, January 28, 2020 |
| APPL NO | 16/774946 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 15/26 (20130101) Original (OR) Class Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 11/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254615 | Raj et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado) |
| INVENTOR(S) | Rishi Raj (Boulder, Colorado); Niriaina Andriamady (Boulder, Colorado); Thomas Clemenceau (Boulder, Colorado); Shikhar Jha (Pittsburgh, Pennsylvania) |
| ABSTRACT | Methods of forming structures including a substrate (e.g., ceramic) and an interface layer comprising a metal are disclosed. Structures and electrochemical cells and batteries are also disclosed. Exemplary methods include flash sintering of metal and ceramic materials. Various structures may be suitable for use as solid electrolytes in solid-state electrochemical cells, as well as for many other applications. |
| FILED | Wednesday, September 19, 2018 |
| APPL NO | 16/136063 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/64 (20130101) C04B 35/111 (20130101) C04B 35/486 (20130101) Original (OR) Class C04B 2235/66 (20130101) C04B 2235/3203 (20130101) C04B 2235/3227 (20130101) C04B 2235/3244 (20130101) C04B 2235/5436 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0562 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254617 | Saito et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); The ExOne Company (North Huntingdon, Pennsylvania) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); The ExOne Company (North Huntingdon, Pennsylvania) |
| INVENTOR(S) | Tomonori Saito (Knoxville, Tennessee); Amy M. Elliott (Knoxville, Tennessee); Daniel T. Brunermer (Leechburg, Pennsylvania); Dustin Blake Gilmer (Kingsport, Tennessee); Michelle Lehmann (Knoxville, Tennessee); Huayun Yu (Delmont, Pennsylvania) |
| ABSTRACT | A method for binder jetting additive manufacturing of an object, the method comprising: (i) separately feeding a powder from which said object is to be manufactured and a solution comprising an adhesive polymer dissolved in a solvent into an additive manufacturing device, wherein said adhesive polymer is an amine-containing polymer having a molecular weight of at least 200 g/mole and is present in said solution in a concentration of 1-30 wt % to result in said solution having a viscosity of 2-25 mPa·s and a surface tension of 25-45 mN/m at room temperature; and (ii) dispensing selectively positioned droplets of said adhesive polymer, from a printhead of said additive manufacturing device, into a bed of said powder to bind particles of said powder with said adhesive polymer to produce a preform having a shape of the object to be manufactured. |
| FILED | Wednesday, January 09, 2019 |
| APPL NO | 16/243507 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0074 (20130101) B22F 3/1003 (20130101) B22F 10/10 (20210101) B22F 12/00 (20210101) B22F 2301/35 (20130101) B22F 2998/00 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/14 (20130101) C04B 35/64 (20130101) C04B 35/63444 (20130101) Original (OR) Class C04B 2235/32 (20130101) C04B 2235/96 (20130101) C04B 2235/3418 (20130101) C04B 2235/6026 (20130101) C04B 2235/6567 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254637 | Dutta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NATIONAL TECHNOLOGY and ENGINEERING SOLUTIONS OF SANDIA, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Tanmoy Dutta (Berkeley, California); Jian Sun (Albany, California); Blake A. Simmons (San Francisco, California); Seema Singh (Clarksburg, Maryland) |
| ABSTRACT | Disclosed herein are lignin-derived ionic liquids and methods for preparing them. The methods include forming a reaction mixture comprising a lignin-derived starting material, a carbonyl compound, and an amine; maintaining the reaction mixture under conditions sufficient to form a lignin-derived aminophenol; and converting the lignin derived aminophenol to the lignin-derived ionic liquid. Monomeric phenols, oligomeric phenols, and polymeric phenols can be used as lignin-derived starting materials. |
| FILED | Wednesday, June 07, 2017 |
| APPL NO | 16/308432 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 217/58 (20130101) Original (OR) Class C07C 2601/16 (20170501) Derivatives of Natural Macromolecular Compounds C08H 8/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2300/00 (20130101) H01M 2300/0045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254708 | Williams et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Robert F. Williams (Los Alamos, New Mexico); David Owen Baumann (Los Alamos, New Mexico); John Cameron Gordon (Los Alamos, New Mexico) |
| ABSTRACT | The present disclosure provides peptoid-based chelating ligands, corresponding cyclic peptoids, and methods of making thereof. Functional groups may be tailored for high metal binding affinity and selectivity. The side chains of a cyclic peptoid according to the present disclosure may be selected based on, for example, high affinity for actinide or other metal ions, selectivity for actinide or other metal ions, the ability to recover a metal once it is bound to the peptoid, and whether the overall peptoid should be hydrophobic or hydrophilic. Unlike siderophores, peptoid-based chelating ligands of the present disclosure are not readily hydrolyzed under physiological conditions. Therefore, peptoid-based chelating ligands may be, for example, used to treat actinide (e.g., iron and lead) poisoning in vivo. Moreover, peptoid-based chelating ligands of the present disclosure may be used for medical imaging, chelation therapy, drug delivery, and separation technologies, for example. |
| FILED | Wednesday, October 09, 2019 |
| APPL NO | 16/596992 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/64 (20170801) A61K 49/0056 (20130101) Peptides C07K 7/54 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254880 | Sunkara et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Advanced Energy Materials, LLC (Louisville, Kentucky) |
| ASSIGNEE(S) | Advanced Energy Materials, LLC (Louisville, Kentucky) |
| INVENTOR(S) | Mahendra Sunkara (Louisville, Kentucky); Sivakumar Vasireddy (Louisville, Kentucky); Juan He (Louisville, Kentucky) |
| ABSTRACT | The present invention relates to the use of adsorbents comprising zinc oxide nanowires decorated with catalytically active metal particles for the removal of sulfur from hydrocarbon feedstocks, including the desulfurization of diesel fuels and the deep desulfurization of natural gas, and to the use of decorated zinc oxide nanowire adsorbents for the hydrogenation of naphthalene selectively to tetralin in the presence of sulfur compounds. The adsorbent comprises nickel metal particles or nickel-zinc alloy particles deposited on zinc oxide nanowires. |
| FILED | Monday, April 06, 2020 |
| APPL NO | 16/841405 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 19/0005 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/06 (20130101) B01J 20/08 (20130101) B01J 20/0225 (20130101) B01J 20/0244 (20130101) B01J 20/28023 (20130101) Acyclic or Carbocyclic Compounds C07C 5/11 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 25/003 (20130101) Original (OR) Class C10G 2300/104 (20130101) C10G 2300/202 (20130101) C10G 2300/207 (20130101) C10G 2300/1003 (20130101) C10G 2300/1044 (20130101) C10G 2300/1051 (20130101) C10G 2300/1055 (20130101) C10G 2300/1059 (20130101) C10G 2300/4018 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254954 | McKinlay et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | James McKinlay (Bloomington, Indiana); Amanda Posto (Stinesville, Indiana); Timothy Kremer (Bloomington, Indiana); Breah LaSarre (Bloomington, Indiana) |
| ABSTRACT | Chemically defined culture medium and culture conditions that allow bacteria to assimilate dinitrogen gas (N2) as a nitrogen source during bio-ethanol production are disclosed herein. Methods of bioethanol production using the chemically defined culture medium and culture conditions are also disclosed. |
| FILED | Monday, December 21, 2015 |
| APPL NO | 15/540326 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 1/38 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/04 (20130101) C12P 7/10 (20130101) C12P 7/16 (20130101) C12P 7/065 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254961 | Arlow et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Daniel Arlow (Berkeley, California); Sebastian Palluk (Berkeley, California) |
| ABSTRACT | Provided herein, among other things, is a conjugate comprising a polymerase and a nucleoside triphosphate, where the polymerase and the nucleoside triphosphate are covalently linked via a linker that comprises a cleavable linkage. A set of such conjugates, where the conjugates correspond to G, A, T (or U) and C is also provided. Methods for synthesizing a nucleic acid of a defined sequence are also provided. The conjugates can also be used for sequencing applications. |
| FILED | Friday, December 21, 2018 |
| APPL NO | 16/230438 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 19/00 (20130101) C07K 2319/21 (20130101) C07K 2319/24 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1241 (20130101) C12N 9/1252 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) C12Q 1/6876 (20130101) C12Q 2521/101 (20130101) C12Q 2525/117 (20130101) C12Q 2525/186 (20130101) C12Q 2525/197 (20130101) Enzymes C12Y 207/07 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255003 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Ying Yang (Farragut, Tennessee); Bruce A. Pint (Knoxville, Tennessee); Jonathan D. Poplawsky (Knoxville, Tennessee); Lizhen Tan (Knoxville, Tennessee) |
| ABSTRACT | A Fe—Ni based alloy comprising, in weight percent: Ni 30-35; Cr 12-14; Al 3-5; Ti 0-2; Ta 2-8; C<=0.05; B<=0.005; Zr<=0.2; Si<0.5; where Cr/(Cr+Fe+Ni)=0.125-0.145; Al/(Al+Ti+Ta)=0.15-0.5; and Fe≥Ni; balance Fe, the alloy having a face-centered cubic (fcc) matrix with from 25 to 30 vol. % of L12-type γ′-Ni3M (M=Al, Ta, Ti and mixtures thereof) precipitates. |
| FILED | Monday, March 30, 2020 |
| APPL NO | 16/834767 |
| ART UNIT | 1738 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Alloys C22C 30/00 (20130101) Original (OR) Class C22C 38/08 (20130101) C22C 38/18 (20130101) C22C 38/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255220 | McGrail et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | B. Peter McGrail (Pasco, Washington); Jeromy J. Jenks (Hines, Oregon); Bruce E. Bernacki (Kennewick, Washington) |
| ABSTRACT | Heat exchanger assemblies and methods for providing heat exchange as well as methods providing specific energy to predetermined materials within an assembly as well as gas turbine engines as well as methods of powering same are provided. Heating assemblies are provided that can include: a heat-sinking substrate; and a selective emitter layer in thermal communication with the substrate. These assemblies can be provided as part of heat exchanger assemblies. Methods for providing heat to a fluid are also provided that can include heating a layer upon a substrate to provide photons of a predetermined wavelength to a fluid from the layer. Turbine combustion engines are also provided that can include a turbine having at least a portion of the blades in the hot section of the turbine coated with an emissivity layer in thermal communication with the turbine blade. Methods for powering turbine combustion engines are also provided. |
| FILED | Friday, October 02, 2020 |
| APPL NO | 17/062259 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/288 (20130101) F01D 25/12 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255575 | Abbasi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GAS TECHNOLOGY INSTITUTE (Des Plaines, Illinois) |
| ASSIGNEE(S) | GAS TECHNOLOGY INSTITUTE (Des Plaines, Illinois) |
| INVENTOR(S) | Hamid Abbasi (Naperville, Illinois); David Cygan (Villa Park, Illinois); S. B. Reddy Karri (Naperville, Illinois); John Findlay (Homer Glen, Illinois) |
| ABSTRACT | A thermal conveyance system and process for absorbing, transporting, storing, and recovering thermal energy (both hot and cold energy) over a wide range of temperatures from up to 2,100° F., or higher, or cool energy at subzero temperatures in inert and stable particles without the need to maintain a minimum temperature or requiring high system pressures. The process involving the transferring thermal energy to a first transfer fluid and recovering thermal energy from a second transfer fluid wherein the first and the second transfer fluids comprise a two phase thermal media including a gaseous carrier containing a quantity of micron to millimeter sized solid particles. |
| FILED | Monday, March 20, 2017 |
| APPL NO | 15/463333 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Solar Heat Collectors; Solar Heat Systems F24S 60/00 (20180501) Original (OR) Class F24S 80/20 (20180501) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 13/00 (20130101) F28D 20/023 (20130101) F28D 20/028 (20130101) F28D 20/0056 (20130101) F28D 2020/0021 (20130101) F28D 2020/0082 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/40 (20130101) Y02E 60/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255933 | Marple |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Maxwell Marple (Berkeley, California) |
| ABSTRACT | A magic angle sample spinning nuclear magnetic resonance system including a housing, a cryogenic fluid in the housing, a magnet in the housing, a probe in the housing, a magic angle sample spinning insert in the probe, a sample battery in the magic angle sample spinning insert, a photovoltaic cell in the magic angle sample spinning insert wherein the photovoltaic cell is connected to the sample battery, an optic fiber operatively connected to the photovoltaic cell, and a laser operatively connected to the optic fiber wherein the laser provides power to charge the sample battery during the magic angle sample spinning nuclear magnetic resonance. |
| FILED | Tuesday, December 15, 2020 |
| APPL NO | 17/122233 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/46 (20130101) G01R 33/307 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255986 | McGregor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Douglas S. McGregor (Riley, Kansas) |
| ASSIGNEE(S) | Douglas S. McGregor (Riley, Kansas) |
| INVENTOR(S) | Douglas S. McGregor (Riley, Kansas); Ryan G. Fronk (Manhattan, Kansas); Michael A. Reichenberger (Mount Hope, Kansas) |
| ABSTRACT | A radiation detector to monitor the neutron flux of a nuclear reactor or other high-radiation environment, that can withstand the high temperatures and radiation fields of such environment, is provided. A small dielectric substrate with a low neutron-activation cross section is provided. The substrate is coated with a neutron conversion material, such as uranium oxide or thorium oxide. One or more substrates form a micro-sized detection cavity that is filled with a detection gas. A voltage is provided across anode and cathode wires in the detection cavity. A neutron absorbed in the conversion material may release reaction products into the gas, causing ionization of the gas which then produces a current or voltage signal. The small detector volume minimizes energy deposition into the detection gas by competing particles such as gamma rays, fast electrons, and beta particles, and therefore minimizes false counts while retaining large signals from neutron interactions. |
| FILED | Thursday, February 08, 2018 |
| APPL NO | 15/891479 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 3/008 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 47/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11256112 | Lipson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Michal Lipson (New York, New York); James Hone (New York, New York); Nanfang Yu (Fort Lee, New Jersey); Ipshita Datta (New York, New York); Sanghoon Chae (New York, New York); Gaurang R Bhatt (New York, New York); Dmitri N Basov (New York, New York) |
| ABSTRACT | Methods, systems, and devices are described for electro-optic tuning. An example device may comprise a first layer comprising a transition metal di-chalcogenide material, a second layer comprising a conductive material, and a third layer comprising a dielectric material. The third layer may be disposed at least partially between the first layer and the second layer. An electrical potential difference applied between the first layer and the second layer may cause a tunable refractive index change in the first layer. |
| FILED | Thursday, February 21, 2019 |
| APPL NO | 16/282013 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0102 (20130101) Original (OR) Class G02F 2203/11 (20130101) G02F 2203/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11257602 | O'Hara |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Matthew J. O'Hara (Richland, Washington) |
| ABSTRACT | A new column-based purification system and approach are described for rapid separation and purification of the alpha-emitting therapeutic radioisotope 211At from dissolved cyclotron targets that provide highly reproducible product results with excellent 211At species distributions and high antibody labeling yields compared with prior art manual extraction results of the prior art that can be expected to enable enhanced production of purified 211At isotope products suitable for therapeutic medical applications such as treatment of cancer in human patients. |
| FILED | Thursday, March 08, 2018 |
| APPL NO | 15/915283 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/00 (20130101) Separation B01D 15/12 (20130101) B01D 15/14 (20130101) B01D 15/20 (20130101) B01D 15/426 (20130101) B01D 59/20 (20130101) Conversion of Chemical Elements; Radioactive Sources G21G 1/001 (20130101) Original (OR) Class G21G 2001/0094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11257682 | Young et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Matthias John Young (Lemont, Illinois); Steven Payonk Letourneau (Naperville, Illinois); Devika Choudhury (Naperville, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); Angel Yanguas-Gil (Northbrook, Illinois); Anil U. Mane (Lemont, Illinois) |
| ABSTRACT | A method of etching an organic or hybrid inorganic/organic material. The method etches molecular layer deposition coatings. An etching cycle comprises a first half reaction exposing the coating to a precursor. A second half reaction exposes a second precursor, removing or etching a portion of the coating. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/588176 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0228 (20130101) H01L 21/0272 (20130101) H01L 21/0331 (20130101) H01L 21/02178 (20130101) H01L 21/02205 (20130101) H01L 21/31116 (20130101) Original (OR) Class H01L 21/31138 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11257856 | Paiella et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Roberto Paiella (Boston, Massachusetts); Leonard Kogos (Salem, Massachusetts) |
| ABSTRACT | A lens-free ultrathin imaging sensor using a compound-eye vision modality can be formed by forming a metasurface on each pixel of an array of pixels in a solid state imaging sensor. The metasurface can be configured to form a diffraction grating that directs light incident on the metasurface at a predefined angle to excite surface plasmon polaritons into the solid state imaging sensor and light incident at any other angle is reflected or diffracted away from the metasurface. Each pixel of the imaging sensor can be configured using the metasurface to only receive light incident from a different portion of a field of view. A computational imaging system can be used to construct the image from the individual pixels. |
| FILED | Friday, October 12, 2018 |
| APPL NO | 16/754919 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/1828 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/1462 (20130101) H01L 27/1463 (20130101) H01L 27/14625 (20130101) Original (OR) Class H01L 31/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11258096 | Spoerke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Erik David Spoerke (Albuquerque, New Mexico); Stephen Percival (Albuquerque, New Mexico); Leo J. Small (Albuquerque, New Mexico) |
| ABSTRACT | A molten sodium-based battery comprises a robust, highly Na-ion conductive, zero-crossover separator and a fully inorganic, fully liquid, highly cyclable molten cathode that operates at low temperatures. |
| FILED | Monday, September 09, 2019 |
| APPL NO | 16/564751 |
| ART UNIT | 1728 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/368 (20130101) H01M 4/381 (20130101) H01M 4/661 (20130101) H01M 4/663 (20130101) H01M 10/054 (20130101) H01M 10/0563 (20130101) Original (OR) Class H01M 2300/0048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11258300 | Lundstrom et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Blake Richard Lundstrom (Lakewood, Colorado); Sourav Kumar Patel (Minneapolis, Minnesota); Murti Salapaka (Plymouth, Minnesota) |
| ABSTRACT | A management device includes at least one processor communicatively coupled to at least one energy resource controller controlling at least one energy resource and to at least one deferrable load controller controlling power to at least one deferrable load. The is configured to receive an indication, determined based on a frequency value of an electrical network and a nominal frequency value, that a frequency anomaly event has occurred. Responsive to receiving the indication that the frequency anomaly event has occurred, the processor is also configured to determine, for at least one of the energy resource and the deferrable load, based on the frequency value, the nominal frequency value, and a power value of the electrical network, a respective power command, and cause at least one of the at least one energy resource and the at least one deferrable load to modify operation based on the respective power command. |
| FILED | Friday, July 17, 2020 |
| APPL NO | 16/931738 |
| ART UNIT | 2119 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/12 (20130101) H02J 13/00007 (20200101) H02J 13/0017 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11258322 | Karmaker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TECO-Westinghouse Motor Company (Round Rock, Texas) |
| ASSIGNEE(S) | TECO-Westinghouse Motor Company (Round Rock, Texas) |
| INVENTOR(S) | Haran Chandra Karmaker (Round Rock, Texas); Edward Kuan-Chen Chen (Austin, Texas); James Arnold Keck (Round Rock, Texas); Paulo Guedes-Pinto (Round Rock, Texas) |
| ABSTRACT | In one embodiment, a high speed induction machine includes: a stator formed of a first plurality of laminations having a thickness of less than approximately 0.01 inch and a winding comprising a coil formed of Litz wire adapted about the stator; and a rotor adapted within the stator. The rotor may include: a rotor core formed of a second plurality of laminations having a second thickness of greater than approximately 0.10 inch and formed of high strength steel and sandwiched between a first end region including at least one first peripheral second lamination and a second end region including at least one second peripheral second lamination, the first end region having a first end ring retained by a first retaining ring adapted there around, the second end region having a second end ring retained by a second retaining ring adapted there around. |
| FILED | Thursday, December 20, 2018 |
| APPL NO | 16/227639 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 1/16 (20130101) H02K 1/26 (20130101) H02K 1/30 (20130101) H02K 3/12 (20130101) H02K 3/24 (20130101) Original (OR) Class H02K 3/42 (20130101) H02K 15/12 (20130101) H02K 15/028 (20130101) H02K 2203/15 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11258370 | Ledezma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TECO-Westinghouse Motor Company (Round Rock, Texas) |
| ASSIGNEE(S) | TECO-Westinghouse Motor Company (Round Rock, Texas) |
| INVENTOR(S) | Enrique Ledezma (Austin, Texas); Paulo Guedes-Pinto (Round Rock, Texas); Randall Pipho (Leander, Texas); Bhaskara Palle (Round Rock, Texas); Ryan Edwards (Round Rock, Texas); Alex Skorcz (Cedar Park, Texas) |
| ABSTRACT | In one aspect, a medium voltage power converter includes a plurality of slices each having: a transformer including a plurality of primary windings to couple to a utility source of input power and a plurality of secondary windings; and a plurality of power cubes coupled to the plurality of secondary windings, each of the plurality of power cubes comprising a low frequency front end stage, a DC link, and a high frequency silicon carbide (SiC) inverter stage to couple to a high frequency load or to a high speed machine. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 16/205879 |
| ART UNIT | 2846 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/2876 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 5/4585 (20130101) Original (OR) Class Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 27/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11258594 | Qi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Bing Qi (Knoxville, Tennessee); Philip G. Evans (Knoxville, Tennessee); Warren P. Grice (Oak Ridge, Tennessee) |
| ABSTRACT | A passive continuous-variable quantum key distribution scheme, where Alice splits the output of a thermal source into two spatial modes, measures one locally and transmits the other mode to Bob after applying attenuation. A secure key can be established based on measurements of the two modes without the use of a random number generator or an optical modulator. |
| FILED | Wednesday, November 21, 2018 |
| APPL NO | 16/197457 |
| ART UNIT | 2434 — Cryptography and Security |
| CURRENT CPC | Transmission H04B 10/70 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0852 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11253600 | Mejia Oneto et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TAMBO, INC. (San Francisco, California); THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| ASSIGNEE(S) | TAMBO, INC. (San Francisco, California); THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| INVENTOR(S) | Jose Manuel Mejia Oneto (San Francisco, California); Nathan Yee (San Francisco, California); Maksim Royzen (San Francisco, California); Sangeetha Srinivasan (San Francisco, California); Ethan Miller (San Francisco, California) |
| ABSTRACT | Cyclooctene conjugates of therapeutic or diagnostic agents have improved aqueous solubility and can release the agents upon contact with a tetrazine-containing biomaterial. The cyclooctene conjugates provide site-selective delivery of agents at the location of the tetrazine-containing biomaterial in a subject. The compositions and methods have applications in the treatment of various diseases or conditions including cancer, tumor growths, and bacterial infections. |
| FILED | Friday, April 06, 2018 |
| APPL NO | 16/603471 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/61 (20170801) A61K 47/542 (20170801) A61K 47/545 (20170801) Original (OR) Class A61K 49/0041 (20130101) A61K 49/0043 (20130101) A61K 49/0052 (20130101) A61K 49/0054 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253846 | Girolami et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Gregory S. Girolami (Champaign, Illinois); Sumeng Liu (Nanjin, China PRC) |
| ABSTRACT | Provided herein are methods of catalytic hydrosilylation, including triggerable methods, using metal-ligand complexes as catalysts, characterized by formula MLxDy; wherein: M is a metal; x is equal to the oxidation state of M; each D is independently a neutral coordinating ligand; y is zero or an integer selected from the range of 1 to 4; and each L is independently a mono-anionic ligand. L may be a η1,η2-β,β-disubstituted-ω-alkenyl ligand. |
| FILED | Friday, March 13, 2020 |
| APPL NO | 16/817858 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/1641 (20130101) Original (OR) Class B01J 2531/11 (20130101) B01J 2531/827 (20130101) B01J 2531/828 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254781 | Langer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Biocant-Center of Innovation and Biotechnology (Cantanhede, Portugal) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Biocant-Center of Innovation and Biotechnology (Cantanhede, Portugal) |
| INVENTOR(S) | Robert S. Langer (Newton, Massachusetts); Jeffrey M. Karp (Chestnut Hill, Massachusetts); Maria Jose Maio Nunes-Pereira (Lisbon, Portugal); Ben Ouyang (Toronto, Canada); Lino da Silva Ferreira (Coimbra, Portugal); Debanjan Sarkar (Williamsville, New York) |
| ABSTRACT | Among other things, the present disclosure provides compositions and methods for an elastomeric cross-linked polyester material. Such an elastomeric cross-linked polyester material, in some embodiments, comprises a plurality of polymeric units of the general formula (-A-B-)p, wherein p is an integer greater than 1; and a plurality of urethane cross-links each of which covalently links two polymeric units to one another, which two linked polymeric unit each had at least one free hydroxyl or amino group prior to formation of the crosslink. |
| FILED | Thursday, February 25, 2021 |
| APPL NO | 17/185528 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/703 (20130101) A61K 9/7084 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/14 (20130101) C08G 18/4236 (20130101) Original (OR) Class C08G 18/4238 (20130101) C08G 18/4283 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254786 | Harth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Eva M. Harth (Houston, Texas); David J. Calkins (Nashville, Tennessee); Alice E. Van Der Ende (Antioch, Tennessee) |
| ABSTRACT | In one aspect, the invention relates to polymers, crosslinked polymers, functionalized polymers, nanoparticles, and functionalized nanoparticles and methods of making and using same. In one aspect, the invention relates to degradable polymers and degradable nanoparticles. In one aspect, the invention relates to methods of preparing degradable nanoparticles and, more specifically, methods of controlling particle size during the preparation of degradable nanoparticles. In one aspect, the degradable nanoparticles are useful for complexing, delivering, and releasing payloads, including pharmaceutically active payloads. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Wednesday, August 21, 2019 |
| APPL NO | 16/547392 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 9/5153 (20130101) A61K 47/58 (20170801) A61K 47/59 (20170801) A61K 47/593 (20170801) A61K 47/595 (20170801) A61K 49/0041 (20130101) A61K 49/0056 (20130101) A61K 49/0093 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/08 (20130101) C08G 63/78 (20130101) C08G 63/912 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254918 | Sonnenburg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); Novome Biotechnologies, Inc. (Daly City, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); Novome Biotechnolooies, Inc. (Daly City, California) |
| INVENTOR(S) | Justin L. Sonnenburg (Redwood City, California); Weston R. Whitaker (Daly City, California); Elizabeth Stanley (Portola Valley, California); William C. DeLoache (Oakland, California) |
| ABSTRACT | Compositions and methods are provided for modulating growth of a genetically modified bacterial cell present in a human organ, for modulating growth of a genetically modified bacterial cell in an organ (e.g., gut), for displacing at least a portion of a population of bacterial cells in an organ, and for facilitating gut colonization by a genetically modified bacterial cell. Also provided are genetically modified bacterial cells, e.g., cells that include a heterologous carbohydrate-utilization gene or gene set that provides for the ability to utilize as a carbon source a rare carbohydrate of interest that is utilized as a carbon source by less than 50% of bacterial cells present in a human microbiome. |
| FILED | Friday, November 06, 2020 |
| APPL NO | 17/091931 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/741 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/2402 (20130101) Original (OR) Class C12N 15/52 (20130101) C12N 15/74 (20130101) Enzymes C12Y 302/01178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254972 | Minev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Dionis Minev (Cambridge, Massachusetts); Christopher Wintersinger (Jamaica Plain, Massachusetts); William M. Shih (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein, in some embodiments, are methods, compositions and kits for controlling nucleation and assembly of molecular nanostructures, microstructures and macrostructures. |
| FILED | Wednesday, August 02, 2017 |
| APPL NO | 16/322787 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 21/00 (20130101) C07H 21/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6811 (20130101) C12Q 1/6837 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255727 | Scholtz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Chromation Inc. (New York, New York) |
| ASSIGNEE(S) | Chromation Inc. (New York, New York) |
| INVENTOR(S) | James Scholtz (Jamesport, New York); Nadia Pervez (Houston, Texas); Ioannis Kymissis (New York, New York); Michael Gazes (Forest Hills, New York); Tanya Cruz Garza (New York, New York) |
| ABSTRACT | An apparatus includes a substrate transmissive of electromagnetic energy of at least a plurality of wavelengths, having a first end, a second end, a first major face, a second major face, at least one edge, a length, a width, and a thickness, at least a first nanostructure that selectively extracts electromagnetic energy of a first set of wavelengths from the substrate; and an input optic oriented and positioned to provide electromagnetic energy into the substrate via at least one of the first or the second major face of the substrate. Nanostructures can take the form of photonic crystal arrays, a plasmonic structure arrays, or holographic diffraction gratings. The apparatus may be part of a spectrometer. |
| FILED | Thursday, May 14, 2020 |
| APPL NO | 16/874554 |
| ART UNIT | 2896 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) G01J 3/0232 (20130101) G01J 3/0256 (20130101) Original (OR) Class G01J 3/0262 (20130101) G01J 3/1838 (20130101) G01J 3/2803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255799 | Sappok et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Filter Sensing Technologies, Inc. (Malden, Massachusetts) |
| ASSIGNEE(S) | CTS Corporation (Lisle, Illinois) |
| INVENTOR(S) | Alexander Sappok (Cambridge, Massachusetts); Paul Ragaller (Dorchester, Massachusetts); Leslie Bromberg (Sharon, Massachusetts) |
| ABSTRACT | A measurement system and method of conducting cavity resonance and waveguide measurements is disclosed. The cavity or waveguide may be used to monitor the amount, composition, or distribution of a material or sample contained in the cavity or waveguide or passing through the cavity or waveguide. Improved means for operating the measurement system to reduce measurement variability, improve measurement accuracy, and decrease measurement response times are described. The invention's broad applications range from measurements of filters, catalysts, pipe, and ducts where the material collected in or passing through the cavity or waveguide exhibits dielectric properties different from the material which it displaces. |
| FILED | Tuesday, May 19, 2020 |
| APPL NO | 16/878176 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/44 (20130101) G01N 22/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255814 | Karhanek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Miloslav Karhanek (Santa Cruz, California); Chris David Webb (Watsonville, California); Senkei Umehara (Tokyo, Japan); Nader Pourmand (San Mateo, California) |
| ABSTRACT | Disclosed are methods and devices for biomolecular detection, comprising a nanopipette, exemplified as a hollow inert, non-biological structure with a conical tip opening of nanoscale dimensions, suitable for holding an electrolyte solution which may contain an analyte such as a protein biomolecule to be detected as it is passed through the tip opening. Biomolecules are detected by specific reaction with peptide ligands chemically immobilized in the vicinity of the tip. Analytes which bind to the ligands cause a detectible change in ionic current. A sensitive detection circuit, using a feedback amplifier circuit, and alternating voltages is further disclosed. Detection of IL-10 at a concentration of 4 ng/ml is also disclosed, as is detection of VEGF. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/588326 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/42 (20130101) Original (OR) Class G01N 27/4035 (20130101) G01N 33/48707 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255848 | Strano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael S. Strano (Lexington, Massachusetts); Jingqing Zhang (Cambridge, Massachusetts); Paul Walter Barone (Allston, Massachusetts); Daniel A. Heller (Rye Brook, New York); Jong-Ho Kim (Ansan, South Korea) |
| ABSTRACT | A composition can include a complex, where the complex includes a photoluminescent nanostructure and a polymer free from selective binding to an analyte, the polymer adsorbed on the photoluminescent nanostructure, and a selective binding site associated with the complex. |
| FILED | Friday, May 26, 2017 |
| APPL NO | 15/606525 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11256000 | Xue et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University Corporation for Atmospheric Research (Boulder, Colorado) |
| ASSIGNEE(S) | University Corporation for Atmospheric Research (Boulder, Colorado) |
| INVENTOR(S) | Lulin Xue (Broomfield, Colorado); Roy M. Rasmussen (Longmont, Colorado); Sarah Anne Tessendorf (Longmont, Colorado) |
| ABSTRACT | A method and system for determining cloud seeding potential comprises receiving a temperature and a liquid water content (LWC). A seeding index is calculated based on the temperature T, a temperature membership function ƒ(T), the LWC, and a liquid water content membership function ƒ(LWC) at the plurality of grid points to create a seeding index set. A target region potential flag is set based on the seeding index set. |
| FILED | Thursday, January 17, 2019 |
| APPL NO | 16/250807 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 15/00 (20130101) Meteorology G01W 1/04 (20130101) Original (OR) Class G01W 1/10 (20130101) G01W 2201/00 (20130101) Electric Digital Data Processing G06F 17/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11256321 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Nam Sung Kim (Champaign, Illinois); Mohammad Alian (Urbana, Illinois) |
| ABSTRACT | A server system including an enhanced Network Interface Controller (NIC) within a client-server architecture is provided. The server system includes a memory for storing data from one or more network packets and one or more processors for processing network requests based on the one or more network packets. The enhanced NIC is configured to receive the one or more network packets and transfer the data from the one or more network packets to the memory. During a latency period defined from the time required to transfer the network packet to memory, the enhanced NIC performs a Network-driven, packet Context Aware Power (NCAP) management process in order to actively transition a power management state of the one or more processors to a predicted level. In this manner, computational and energy efficiency of the server system is improved. |
| FILED | Friday, June 29, 2018 |
| APPL NO | 16/024290 |
| ART UNIT | 2187 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 1/324 (20130101) G06F 1/3209 (20130101) G06F 1/3237 (20130101) G06F 1/3287 (20130101) G06F 1/3296 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 67/02 (20130101) H04L 67/10 (20130101) H04L 67/42 (20130101) H04L 67/322 (20130101) H04L 69/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11257077 | Agrawal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Visa International Service Association (San Francisco, California); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | Visa International Service Association (San Francisco, California); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Shashank Agrawal (Mountain View, California); Karl Benedikt Bünz (Palo Alto, California); Mahdi Zamani (Palo Alto, California); Dan Boneh (Stanford, California) |
| ABSTRACT | Blockchain-based, smart contract platforms have great promise to remove trust and add transparency to distributed applications. However, this benefit often comes at the cost of greatly reduced privacy. Techniques for implementing a privacy-preserving smart contract is described. The system can keep accounts private while not losing functionality and with only a limited performance overhead. This is achieved by building a confidential and anonymous token on top of a cryptocurrency. Multiple complex applications can also be built using the smart contract system. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 16/206661 |
| ART UNIT | 3685 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 20/383 (20130101) Original (OR) Class G06Q 20/0658 (20130101) G06Q 20/3678 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/008 (20130101) H04L 9/0637 (20130101) H04L 9/3218 (20130101) H04L 9/3239 (20130101) H04L 2209/38 (20130101) H04L 2209/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11257584 | Buckler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Elucid Bioimaging Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| INVENTOR(S) | Mary E. Buckler (Wenham, Massachusetts); Xiaonan Ma (South Hamilton, Massachusetts); Lawrence Martell (Wenham, Massachusetts); Andrew J. Buckler (Boston, Massachusetts) |
| ABSTRACT | Advanced reporting systems based on ontology development for quantitative imaging biomarkers, information modeling to integrate heterogeneous data types relevant to quantitative medical analysis, and a knowledge representation framework for their statistical validation. |
| FILED | Monday, August 13, 2018 |
| APPL NO | 16/102042 |
| ART UNIT | 2657 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 16/367 (20190101) G06F 16/3329 (20190101) G06F 40/30 (20200101) G06F 40/211 (20200101) G06F 40/242 (20200101) G06F 40/284 (20200101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 15/00 (20180101) G16H 30/20 (20180101) Original (OR) Class G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11257665 | Jarrold et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana) |
| ASSIGNEE(S) | The Trustees Of Indiana University (Bloomington, Indiana) |
| INVENTOR(S) | Martin F. Jarrold (Bloomington, Indiana); Staci N. Anthony (Grandview, Ohio); Benjamin E. Draper (Bloomington, Indiana) |
| ABSTRACT | An interface transports ions from a first pressure environment to a lower pressure analysis instrument and may include a first region pumped to a second pressure less than the first pressure, a first ion funnel disposed in the first region, a first ion carpet in the first region opposite an ion outlet end of the first ion funnel, a second region pumped to a third pressure less than the second pressure and greater than the instrument pressure, a second ion funnel disposed in the second region and a second ion carpet in the second region opposite an ion outlet end of the second ion funnel. Ions from the environment pass sequentially through the first and second ion funnels and into the analysis instrument. Each of the first and second ion funnels define a tapered axial passageway therethrough each defining a respective virtual jet disrupter therein. |
| FILED | Tuesday, June 04, 2019 |
| APPL NO | 17/058544 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/022 (20130101) H01J 49/24 (20130101) H01J 49/025 (20130101) H01J 49/066 (20130101) Original (OR) Class H01J 49/425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11258134 | McVerry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Brian T. McVerry (Laguna Hills, California); Ethan Rao (Los Angeles, California); Robert S. Jordan (Merced, California); Richard B. Kaner (Los Angeles, California) |
| ABSTRACT | Disclosed herein are compositions for use in an energy providing devices and methods of preparing such devices. Also included herein is energy providing devices that comprise a charged compound modified substrate or zwitterion-modified substrate or energy providing devices that comprise an electrolyte that comprises a perhalogenatedphenyl azide charged or zwitterionic compound. |
| FILED | Wednesday, February 19, 2020 |
| APPL NO | 16/795138 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 211/62 (20130101) C07C 247/16 (20130101) C07C 309/14 (20130101) C07C 309/88 (20130101) C07C 311/37 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/583 (20130101) H01M 8/106 (20130101) H01M 8/0221 (20130101) H01M 50/411 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11258285 | Shin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Kang G. Shin (Ann Arbor, Michigan); Liang He (Ann Arbor, Michigan) |
| ABSTRACT | An user-interactive charging paradigm is presented that tailors the device charging to the user's real-time needs. The core of approach is a relaxation-aware charging algorithm that maximizes the charged capacity within the user's available time and slows down the battery's capacity fading. The approach also integrates relaxation-aware charging algorithm existing fast charging algorithms via a user-interactive interface, allowing users to choose a charging method based on their real-time needs. The relaxation-aware charging algorithm is shown to slow down the battery fading by over 36% on average, and up to 60% in extreme cases, when compared with existing fast charging solutions. Such fading slowdown translates to, for instance, an up to 2-hour extension of the LTE time for a Nexus 5X phone after 2-year usage, revealed by a trace-driven analysis based on 976 charging cases collected from 7 users over 3 months. |
| FILED | Monday, May 21, 2018 |
| APPL NO | 15/984843 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0003 (20130101) H02J 7/0047 (20130101) H02J 7/0069 (20200101) Original (OR) Class H02J 7/0071 (20200101) H02J 7/0086 (20130101) H02J 7/00718 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11258370 | Ledezma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TECO-Westinghouse Motor Company (Round Rock, Texas) |
| ASSIGNEE(S) | TECO-Westinghouse Motor Company (Round Rock, Texas) |
| INVENTOR(S) | Enrique Ledezma (Austin, Texas); Paulo Guedes-Pinto (Round Rock, Texas); Randall Pipho (Leander, Texas); Bhaskara Palle (Round Rock, Texas); Ryan Edwards (Round Rock, Texas); Alex Skorcz (Cedar Park, Texas) |
| ABSTRACT | In one aspect, a medium voltage power converter includes a plurality of slices each having: a transformer including a plurality of primary windings to couple to a utility source of input power and a plurality of secondary windings; and a plurality of power cubes coupled to the plurality of secondary windings, each of the plurality of power cubes comprising a low frequency front end stage, a DC link, and a high frequency silicon carbide (SiC) inverter stage to couple to a high frequency load or to a high speed machine. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 16/205879 |
| ART UNIT | 2846 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/2876 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 5/4585 (20130101) Original (OR) Class Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 27/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11258405 | Tousi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Yahya Tousi (San Jose, California); Ehsan Afshari (Ithaca, New York) |
| ABSTRACT | A device and method for terahertz signal generation are disclosed. Oscillators are arranged in a two-dimensional array, each oscillator connected to a corresponding antenna. Each oscillator is unidirectional connected to its adjacent oscillators by a phase shifter. A method for generating a steerable terahertz signal utilizes an array of oscillators connected by corresponding phase shifters. A terahertz signal having a fundamental frequency is generated using the array. The phase shift of one or more of the phase shifters is varied in order to vary the fundamental frequency and/or steer the signal generated by the array. |
| FILED | Monday, June 08, 2020 |
| APPL NO | 16/896202 |
| ART UNIT | 2849 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/36 (20130101) H01Q 9/0407 (20130101) H01Q 21/0025 (20130101) H01Q 21/245 (20130101) Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 5/24 (20130101) Original (OR) Class H03B 5/1212 (20130101) H03B 27/00 (20130101) H03B 2200/0084 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/20 (20130101) H04L 49/101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11258410 | Walling et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| ASSIGNEE(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| INVENTOR(S) | Jeffrey Walling (Salt Lake City, Utah); Ali Azam (Salt Lake City, Utah); Zhidong Bai (Salt Lake City, Utah) |
| ABSTRACT | Embodiments of the disclosure are drawn to apparatuses a hybrid switched capacitor array power amplifier (H-SCPA). The H-SCPA may have an array of storage elements divided into sub-arrays. A first sub-array may be configured to receive a delta sigma modulated (DSM) signal. A second sub-array may be configured to receive a Nyquist-rate signal. The H-SCPA may provide an output based on the received DSM and Nyquist-rate signals. The first sub-array and second sub-array may have different architectures. The DSM signal may represent the least significant bits of the signal and the Nyquist-rate signal may represent the most significant bits of the signal. |
| FILED | Thursday, August 01, 2019 |
| APPL NO | 16/528956 |
| ART UNIT | 2843 — Electrical Circuits and Systems |
| CURRENT CPC | Amplifiers H03F 1/565 (20130101) H03F 3/005 (20130101) Original (OR) Class H03F 3/24 (20130101) H03F 2200/331 (20130101) H03F 2200/387 (20130101) H03F 2200/451 (20130101) Transmission H04B 1/0475 (20130101) H04B 2001/0408 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11258879 | Ioannidis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Efstratios Ioannidis (Boston, Massachusetts); Edmund Meng Yeh (Newton, Massachusetts) |
| ABSTRACT | Embodiments solve a problem of minimizing routing costs by jointly optimizing caching and routing decisions over an arbitrary network topology. Embodiments solve an equivalent caching gain maximization problem, and consider both source routing and hop-by-hop routing settings. The respective offline problems are non-deterministic polynomial time (NP)-hard. Nevertheless, embodiments show that there exist polynomial time approximation methods producing solutions within a constant approximation from the optimal. Embodiments herein include distributed, adaptive networks, computer methods, systems, and computer program products that provide guarantees of routing cost reduction. Simulation is performed over a broad array of different topologies. Embodiments reduce routing costs by several orders of magnitude compared to existing approaches, including existing approaches optimizing caching under fixed routing. |
| FILED | Monday, June 18, 2018 |
| APPL NO | 16/623599 |
| ART UNIT | 2441 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 67/327 (20130101) Original (OR) Class H04L 67/2842 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11259352 | Misra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Vishal Misra (New York, New York); Daniel S. Rubenstein (New York, New York) |
| ABSTRACT | Mechanisms for providing multi-homing, comprising: a memory device; and at least one hardware processor coupled to the memory device and configured to: intercept a connection between a device and a server using a proxy; establish a first connection between the device and the proxy; create multiple second connections between the proxy and the server, wherein at least two of the multiple second connections use different connection types; receive a request for blocks of data from the device using the first connection; allocate the blocks of data across the multiple second connections; request the blocks of data from the server using the multiple second connections as allocated; receive the blocks of data from the server using the multiple second connections; and forward the blocks of data to the device using the first connection. |
| FILED | Monday, June 15, 2020 |
| APPL NO | 16/902157 |
| ART UNIT | 2473 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 67/28 (20130101) Wireless Communication Networks H04W 28/0268 (20130101) H04W 76/15 (20180201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11252941 | Soder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Kathy J. Soder (Petersburg, Pennsylvania); Kyle R. Elkin (State College, Pennsylvania); Sandra L. Dillard (Calhoun, Georgia); Dennis R. Bookhamer (Huntingdon, Pennsylvania); Melissa D. Rubano (Petersburg, Pennsylvania) |
| ABSTRACT | A system for monitoring ruminant animal foraging that utilizes a piezoelectric film sensor in communication with a computer processor to record and characterize jaw movement data for the foraging ruminant animal. The processor applies pattern algorithms to categorize the jaw movement data so that the jaw movements are categorized as at least chewing, biting, ruminating, and/or idling. |
| FILED | Wednesday, January 31, 2018 |
| APPL NO | 15/884524 |
| ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 11/008 (20130101) A01K 15/028 (20130101) A01K 27/001 (20130101) A01K 27/009 (20130101) A01K 29/005 (20130101) Original (OR) Class Harness; Devices Used in Connection Therewith; Whips or the Like B68B 1/02 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00362 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11252953 | Werner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, Represented by the Secretary of Agriculture (Washington, District of Columbia); Arkion Life Sciences, LLC (New Castle, Delaware) |
| ASSIGNEE(S) | Arkion Life Sciences, LLC (New Castle, Delaware); United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Scott J. Werner (Wellington, Colorado); Kenneth E. Ballinger, Jr. (Kennett Square, Pennsylvania) |
| ABSTRACT | The combination of a repellent agent or an attractant agent with a wavelength-specific visual cue agent has been found to produce an unexpected and synergistic effect of increased repellency or attraction in dichromatic animals who are not maximally sensitive to the wavelength of the repellent or attractant agent. The method of the invention may be used to repel dichromatic-animal pests; or to prevent or minimize monetary damage, particularly to agricultural products, natural resources or private property. The method of the invention may also be used to attract dichromatic animals for the purpose of agricultural production, recreational opportunities (e.g., wild-rodent feeders), or the effective administration of target-animal pharmaceuticals or mitigation techniques. |
| FILED | Monday, March 30, 2020 |
| APPL NO | 16/833860 |
| ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 29/08 (20130101) Original (OR) Class Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/00 (20130101) A01N 25/00 (20130101) A01N 33/04 (20130101) A01N 35/04 (20130101) A01N 35/06 (20130101) A01N 35/06 (20130101) A01N 37/04 (20130101) A01N 37/10 (20130101) A01N 43/90 (20130101) A01N 47/22 (20130101) A01N 53/00 (20130101) A01N 57/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254700 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF HAWAII (Honolulu, Hawaii) |
| ASSIGNEE(S) | UNIVERSITY OF HAWAII (Honolulu, Hawaii) |
| INVENTOR(S) | Qing X. Li (Honolulu, Hawaii); Zhibin Liang (Honolulu, Hawaii) |
| ABSTRACT | Isoorientin analogues and related compounds that inhibit glycogen synthase kinase-3β activity are provided as are methods of using these compounds in the treatment of cognitive, neurodegenerative or neurological diseases or conditions, as well as cancer, obesity, diabetes, inflammatory or autoimmune disease, cardiovascular disorder, metabolic syndrome X, hair loss, severe acute respiratory syndrome coronavirus, cocaine addiction, dental caries, bone loss and glaucoma. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 16/760700 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 49/835 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 7/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254907 | Dardick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Christopher D. Dardick (Shenandoah Junction, West Virginia); Wojciech J. Janisiewicz (Frederick, Maryland); Zongrang Liu (Winchester, Virginia); Zhijian Li (Martinsburg, West Virginia); Ann M Callahan (Sheperdstown, West Virginia) |
| ABSTRACT | A method of increasing east one growth characteristic of a plant comprising growing a Cladosporium sphaerospermum strain in or on a medium in a container, where a headspace of said C. sphaerospermum in said container is in fluid communication with a headspace of said plant, where said C. sphaerospermum produces at least one volatile organic compound (VOC), where said at least one VOC produced by said C. sphaerospermum causes the plant to have an increase in at least one growth characteristic when compared to the growth characteristic of a plant which has not been exposed to the VOC, and where said C. sphaerospermum comprises an ITS1/2 consensus amplicon of SEQ ID NO: 5 and an ITS3/4 consensus amplicon of SEQ ID NO: 6. |
| FILED | Tuesday, March 19, 2019 |
| APPL NO | 16/357452 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 9/02 (20130101) Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 27/00 (20130101) A01N 63/30 (20200101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/145 (20210501) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/002 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/645 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254945 | Hunter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); AUM LifeTech, Inc. (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia); AUM Lifetech, Inc. (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Wayne B. Hunter (Port St Lucie, Florida); Veenu Aishwarya (Philadelphia, Pennsylvania) |
| ABSTRACT | Herein is disclosed synthetic oligonucleotides comprising 2′F-ANA nucleosides that can be utilized to control plant-chewing and phloem-feeding insects, bacteria present in such insects, and bacteria present in plants. The novel approaches and materials provided herein allow for reduction of pesticide and antibiotic use without the need to create genetically modified plants. |
| FILED | Wednesday, July 03, 2019 |
| APPL NO | 16/502236 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/8218 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/323 (20130101) C12N 2310/346 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255776 | Yalin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| INVENTOR(S) | Azer P. Yalin (Fort Collins, Colorado) |
| ABSTRACT | Systems and methods are disclosed to determine the concentration of a species within a sample. An example method may include collecting optical loss data over a range of frequencies from the sample using a spectroscopy system; placing the optical loss data into a plurality of bins, each bin having a defined frequency width; determining an average optical loss data value for the optical loss values within each bin that have an optical loss value less than a threshold value; removing the optical loss data within each bin having a value outside a tolerance range bounding the average optical loss data value for the respective bin; fitting a spectral curve to the remaining optical loss data; and determining the concentration of the species within the sample based on the spectral curve. |
| FILED | Wednesday, May 23, 2018 |
| APPL NO | 15/987779 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) G01J 2003/423 (20130101) G01J 2003/2869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/39 (20130101) G01N 21/3504 (20130101) Original (OR) Class G01N 2201/1248 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 11253347 | Haupt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States, as Represented by the Secretary of the Army (Fort Detrick, Maryland); Government of the United States of America, as represented by the Secretary of the Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | The Government of the United States, as represented by the Secretary of the Army (Fort Detrick, Maryland); Government of the United States of America, as represented by the Secretary of the Commerce (Gaithersburg, Maryland) |
| INVENTOR(S) | Brett R. Haupt (Thurmont, Maryland); Matthew E. Staymates (Damascus, Maryland); Larry E. Bowen (Williamsport, Maryland); Mark M. Bailey (Gaithersburg, Maryland); Jaime B. Anderson (Hagerstown, Maryland) |
| ABSTRACT | A system for conducting inhalation studies includes an inhalation exposure chamber and an aerosol delivery line connected to the inhalation exposure chamber. The aerosol delivery line is configured to produce a bi-directional and symmetrical presentation of aerosol to the inhalation exposure chamber. A laminar flow element is configured to create an ante-chamber where complete and turbulent mixing of the aerosol occurs. A radial exhaust and the laminar flow element enable laminar flow of the aerosol through the inhalation exposure chamber. |
| FILED | Tuesday, February 07, 2017 |
| APPL NO | 16/076040 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Veterinary Instruments, Implements, Tools, or Methods A61D 7/04 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 15/009 (20130101) A61M 15/0065 (20130101) A61M 15/0086 (20130101) A61M 2205/50 (20130101) A61M 2206/11 (20130101) A61M 2206/16 (20130101) A61M 2250/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11255746 | Ahmed |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Zeeshan Ahmed (Washington, District of Columbia) |
| ABSTRACT | A photonic resonator analyzer characterizes a photonic resonator and incudes a light source that provides a probe light; a photonic resonator that receives the probe light and produces product light; an optical detector that receives the product light and produces a product signal; a mode analyzer that receives the product signal and produces a resonator spectrum; and a spectral analyzer that receives the resonator spectrum, performs regression by fitting a non-parametric model to the resonator spectrum, and produces a thermal response function of the photonic resonator from fitting the non-parametric model to the resonator spectrum to characterize the photonic resonator. |
| FILED | Monday, December 07, 2020 |
| APPL NO | 17/113222 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/32 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 11/33 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 1/005 (20130101) G02B 6/29338 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11256672 | Daimler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Conexus ai, Inc. (San Francisco, California) |
| ASSIGNEE(S) | Conexus ai, Inc. (San Francisco, California) |
| INVENTOR(S) | Eric Alexander Daimler (San Francisco, California); Ryan Jacob Wisnesky (Boston, Massachusetts); David Isaac Spivak (Somerville, Massachusetts) |
| ABSTRACT | A data migration and integration system is disclosed. In various embodiments, the system includes a memory configured to store a mapping from a source schema to a target schema; and a processor coupled to the memory and configured to migrate to a target schema an instance of source data organized according to the source schema, including by using a chase engine to perform an ordered sequence of steps comprising adding a bounded layer of new elements to a current canonical chase state associated with migrating the source data to the target schema; adding coincidences associated with one or more of the target schema data integrity constraints and a mapping from the source schema to the target schema; and merging equal elements based on the coincidences; and repeat the preceding ordered sequence of steps iteratively until an end condition is met. |
| FILED | Thursday, April 09, 2020 |
| APPL NO | 16/844810 |
| ART UNIT | 2169 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/86 (20190101) G06F 16/182 (20190101) G06F 16/211 (20190101) G06F 16/214 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11258415 | Shainline et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Jeffrey Shainline (Boulder, Colorado); Sae Woo Nam (Boulder, Colorado); Sonia Buckley (Boulder, Colorado) |
| ABSTRACT | A neuromimetic circuit includes: a primary single photon optoelectronic neuron; a synapse in optical communication with the primary single photon optoelectronic neuron; and an axonic waveguide in optical communication with the primary single photon optoelectronic neuron and the synapse such that the axonic waveguide optically interconnects the primary single photon optoelectronic neuron and the synapse. |
| FILED | Thursday, December 14, 2017 |
| APPL NO | 15/841701 |
| ART UNIT | 2849 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 1/08 (20130101) Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) G06N 3/063 (20130101) G06N 3/088 (20130101) G06N 3/0472 (20130101) G06N 3/0675 (20130101) Amplifiers H03F 19/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11253838 | Weston et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Numat Technologies Inc. (Skokie, Illinois) |
| ASSIGNEE(S) | NuMat Technologies Inc. (Skokie, Illinois) |
| INVENTOR(S) | Mitchell Hugh Weston (Chicago, Illinois); Edwin Alfonso Argueta Fajardo (Chicago, Illinois) |
| ABSTRACT | This invention relates to a Cu-BTC MOF which is water stable. The Cu-BTC MOF has been modified by substituting some of the BTC ligand (1,3,5, benzene tricarboxylic acid) with 5-aminoisophthalic acid (AIA). The resultant MOF retains at least 40% of its as synthesized surface area after exposure to liquid water at 60° C. for 6 hours. This is an unexpected result versus the MOF containing only the BTC ligand. This MOF can be used to abate contaminants such as ammonia in gas streams and especially air streams. |
| FILED | Friday, August 14, 2020 |
| APPL NO | 16/993803 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/58 (20130101) B01D 53/82 (20130101) B01D 53/8634 (20130101) B01D 2253/204 (20130101) B01D 2255/705 (20130101) B01D 2255/9207 (20130101) B01D 2257/406 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/226 (20130101) Original (OR) Class B01J 20/3085 (20130101) B01J 20/28016 (20130101) B01J 20/28019 (20130101) B01J 20/28038 (20130101) B01J 20/28045 (20130101) B01J 20/28066 (20130101) B01J 20/28073 (20130101) B01J 31/1691 (20130101) B01J 35/04 (20130101) B01J 35/08 (20130101) B01J 35/026 (20130101) B01J 35/1028 (20130101) B01J 37/04 (20130101) B01J 37/10 (20130101) B01J 2231/005 (20130101) B01J 2531/16 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254011 | Fry |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Mark A. Fry (Marco Island, Florida) |
| ABSTRACT | Systems and methods are described, and an example system includes a transport bin configured to carry a baggage item and having spatial reference frame marking detectable by electromagnetic scan and by machine vision. The system includes a robotic arm apparatus at an inspection area, and includes a switched path baggage conveyor that, responsive to electromagnetic scan detection of an object-of-interest (OOI) within the baggage item, conveys the transport bin to the inspection area. The electromagnetic scan generates OOI geometric position information indicating geometric position of the OOI relative to the spatial reference frame marking. The robotic arm apparatus, responsive to receiving the transport bin, uses machine vision to detect orientation of the spatial reference frame marking, then translates OOI geometric position information to local reference frame, for robotic opening of the baggage item, and robotic accessing and contact swab testing on the OOI. |
| FILED | Friday, July 09, 2021 |
| APPL NO | 17/372050 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/043 (20130101) B25J 9/1612 (20130101) B25J 9/1697 (20130101) Original (OR) Class B25J 13/087 (20130101) B25J 19/023 (20130101) B25J 19/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11254623 | Brogden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Michael Brogden (Galloway, New Jersey); Steve Duffy (Hammonton, New Jersey) |
| ABSTRACT | An explosive sheet simulant that uses an ethylene vinyl acetate polymer combined with a mixture of a boron carbide and iron oxide for X-ray attenuating properties, and components of the mixture selected for predetermined flexural modulus combined with particle density, effective atomic number, X-ray transmission properties, or millimeter wave properties. |
| FILED | Friday, March 05, 2021 |
| APPL NO | 17/193370 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 23/001 (20130101) Original (OR) Class Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/38 (20130101) C08K 3/38 (20130101) C08K 2003/265 (20130101) C08K 2003/2244 (20130101) C08K 2003/2265 (20130101) Compositions of Macromolecular Compounds C08L 23/0853 (20130101) C08L 23/0853 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11253489 | Palczewski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Krzysztof Palczewski (Bay Village, Ohio); Philip Kiser (Cleveland, Ohio); Jianye Zhang (Cleveland, Ohio); Mohsen Badiee (Shaker Heights, Ohio); Gregory Tochtrop (Shaker Heights, Ohio) |
| ABSTRACT | A method of treating an ocular disorder in a subject in need thereof includes administering to the subject a therapeutically effective amount of a retinal sequestering compound of formula (I). |
| FILED | Tuesday, February 27, 2018 |
| APPL NO | 16/488890 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 31/137 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11253546 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); SEATTLE CHILDREN'S HOSPITAL (Seattle, Washington) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Seattle Children's Hospital (Seattle, Washington) |
| INVENTOR(S) | Yvonne Y. Chen (Los Angeles, California); Eugenia Zah (Los Angeles, California); Michael C. Jensen (Seattle, Washington) |
| ABSTRACT | A CD19-OR-CD20 chimeric antigen receptor (CAR) protein construct is provided. Also provided are nucleic acids encoding the CD19-OR-CD20 CAR; and methods of use, e.g. in the treatment of B cell malignancies. The CD19-OR-CD20 CAR of the invention is a bispecific CAR that can trigger T-cell activation upon detection of either CD19 or CD20 (or both). It is a single molecule that confers two-input recognition capability upon human T cells engineered to stably express this CAR. |
| FILED | Monday, December 14, 2015 |
| APPL NO | 15/535972 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 14/70596 (20130101) C07K 16/46 (20130101) C07K 16/2803 (20130101) C07K 16/2887 (20130101) C07K 2317/31 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11257381 | Kostiuk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robust Analytics, Inc. (Crofton, Maryland) |
| ASSIGNEE(S) | ROBUST ANALYTICS, INC. (Crofton, Maryland) |
| INVENTOR(S) | Peter F Kostiuk (Crofton, Maryland); Hugo Kang (Crofton, Maryland); Michael Mohen (Crofton, Maryland); Varun Sudarsanan (Crofton, Maryland) |
| ABSTRACT | A system, a method, and a computer program embodied on a non-transitory computer-readable medium, the program configured to cause at least one processor to perform steps including gathering observations and forecasts of a plurality of aviation environmental and operational data of a terminal airspace, independently transforming the observations and forecasts into respective terminal airspace risk factors; integrating the terminal airspace risk factors into operational time periods; weighting the integrated terminal airspace risk factors into an overall airspace risk score for each operational time period; categorizing the overall airspace risk score into a terminal airspace risk category based upon at least one predetermined risk score threshold; and displaying the risk categories and selected underlying risk factors data on a map with a plurality of display panes. |
| FILED | Tuesday, January 21, 2020 |
| APPL NO | 16/748321 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/06 (20130101) Electric Digital Data Processing G06F 3/0482 (20130101) Traffic Control Systems G08G 5/0026 (20130101) G08G 5/0043 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11257604 | Choi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Sang H. Choi (Poquoson, Virginia); Dennis M. Bushnell (Hampton, Virginia); David R. Komar (Hampton, Virginia); Robert C. Hendricks (Cleveland, Ohio) |
| ABSTRACT | The present disclosure is directed to a nuclear thermionic avalanche cell (NTAC) systems and related methods of generating energy comprising a radioisotope core, a plurality of thin-layered radioisotope sources configured to emit high energy beta particles and high energy photons, and a plurality of NTAC layers integrated with the radioisotope core and the radioisotope sources, wherein the plurality of NTAC layers are configured to receive the beta particles and the photons from the radioisotope core and sources, and by the received beta particles and photons, free up electrons in an avalanche process from deep and intra bands of an atom to output a high density avalanche cell thermal energy through a photo-ionic or thermionic process of the freed up electrons. |
| FILED | Thursday, May 30, 2019 |
| APPL NO | 16/426345 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Conversion of Chemical Elements; Radioactive Sources G21G 1/12 (20130101) G21G 2001/0068 (20130101) G21G 2001/0094 (20130101) Obtaining Energy From Radioactive Sources; Applications of Radiation From Radioactive Sources, Not Otherwise Provided For; Utilising Cosmic Radiation G21H 1/04 (20130101) Original (OR) Class G21H 1/12 (20130101) G21H 1/103 (20130101) G21H 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11256672 | Daimler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Conexus ai, Inc. (San Francisco, California) |
| ASSIGNEE(S) | Conexus ai, Inc. (San Francisco, California) |
| INVENTOR(S) | Eric Alexander Daimler (San Francisco, California); Ryan Jacob Wisnesky (Boston, Massachusetts); David Isaac Spivak (Somerville, Massachusetts) |
| ABSTRACT | A data migration and integration system is disclosed. In various embodiments, the system includes a memory configured to store a mapping from a source schema to a target schema; and a processor coupled to the memory and configured to migrate to a target schema an instance of source data organized according to the source schema, including by using a chase engine to perform an ordered sequence of steps comprising adding a bounded layer of new elements to a current canonical chase state associated with migrating the source data to the target schema; adding coincidences associated with one or more of the target schema data integrity constraints and a mapping from the source schema to the target schema; and merging equal elements based on the coincidences; and repeat the preceding ordered sequence of steps iteratively until an end condition is met. |
| FILED | Thursday, April 09, 2020 |
| APPL NO | 16/844810 |
| ART UNIT | 2169 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/86 (20190101) G06F 16/182 (20190101) G06F 16/211 (20190101) G06F 16/214 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11257350 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Microsensor Labs, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | Microsensor Labs, LLC (Chicago, Illinois) |
| INVENTOR(S) | Peng Liu (Chicago, Illinois); Yang Liu (Chicago, Illinois); Jiapeng Huang (Louisville, Kentucky); Darius Cepulis (Forest Park, Illinois) |
| ABSTRACT | A system and method for opportunity-based hygiene monitoring and/or reminding is disclosed. Healthcare providers may have various opportunities to interact with a patient. As such, an opportunity-based focus in managing a healthcare environment may assist in assessing the various opportunities when interacting with the patient. For example, an opportunity-based analysis may be used for protocol compliance, such as compliance with hand hygiene protocols and/or PPE protocols. Further, infection analysis, patient care billing, staff locating, or workload analysis may be opportunity based in order to more efficiently manage the healthcare environment. |
| FILED | Monday, June 08, 2020 |
| APPL NO | 16/895435 |
| ART UNIT | 2685 — Selective Communication |
| CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 1/00 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/18 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10366 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/245 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 11257199 | Ponto et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Kevin Ponto (Madison, Wisconsin); Ross D. Tredinnick (Madison, Wisconsin); Simon P. B. Smith (Stoughton, Wisconsin) |
| ABSTRACT | In accordance with some aspects, systems, methods and media for detecting manipulations of point cloud data are provided. In some aspects, a method for presenting information indicative of whether a manipulation of point cloud data has occurred is provided, the method comprising: receiving point cloud data comprising a plurality of points, wherein each point of the plurality of points is associated with a position; determining, for each of the plurality of points, a value indicative of a density of points in a region surrounding the respective point; associating, for each of the plurality of points, the value indicative of density with the respective point; and causing a representation of at least a portion of the point cloud data to be presented based on the location information associated with each point of the plurality of points, and the value indicative of density associated with each of the plurality of points. |
| FILED | Friday, October 18, 2019 |
| APPL NO | 16/657197 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0002 (20130101) Original (OR) Class G06T 11/001 (20130101) G06T 11/203 (20130101) G06T 2207/10028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 11255783 | Fairey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas); GARVER, LLC (North Little Rock, Arkansas); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE ADMINISTRATOR OF U.S. ENVIRONMENTAL PROTECTION AGENCY (Washington D.C., District of Columbia) |
| ASSIGNEE(S) | BOARD OF TRUSTEE OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE ADMINISTRATOR OF U.S. ENVIRONMENTAL PROTECTION (Washington, District of Columbia) |
| INVENTOR(S) | Julian Fairey (Fayetteville, Arkansas); Thien Duc Do (Fayetteville, Arkansas); Ashley Pifer (Fayetteville, Arkansas); David Wahman (Cincinnati, Ohio) |
| ABSTRACT | This invention relates generally to a system and process for early detection of biological ammonia oxidation in water utilizing a fluorescence-based sensor and process. Various embodiments are configured to read increases in a fluorescence excitation-emission wavelength pair that is responsive to a period of time (days to weeks or even longer) prior to the onset of biological ammonia oxidation, which is considered to be a nitrification event. Fluorescence excitation/emission pairs that have proven to be reliable include a fluorescence excitation wavelength of about 230 nm and an emission wavelength of about 345 nm and an excitation wavelength of 325 and an emission wavelength of 470. The system and process enable drinking water utilities to improve management of its distribution systems and facilitate earlier corrective actions, resulting is less loss of treated water through flushing and other tangible benefits. |
| FILED | Friday, August 30, 2019 |
| APPL NO | 16/556726 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/64 (20130101) Original (OR) Class G01N 21/6486 (20130101) G01N 33/18 (20130101) G01N 33/1846 (20130101) G01N 2021/6495 (20130101) G01N 2021/6497 (20130101) G01N 2021/8416 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/175383 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 11254156 | Mahajan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chaitanya G. Mahajan (Rochester, New York); Denis Cormier (Pittsford, New York); Mark Irving (Rochester, New York); Scott Williams (Livonia, New York); David Borkholder (Canandaigua, New York); Ahmed Alfadhel (Rochester, New York) |
| ASSIGNEE(S) | Rochester Institute of Technology (Rochester, New York) |
| INVENTOR(S) | Chaitanya G. Mahajan (Rochester, New York); Denis Cormier (Pittsford, New York); Mark Irving (Rochester, New York); Scott Williams (Livonia, New York); David Borkholder (Canandaigua, New York); Ahmed Alfadhel (Rochester, New York) |
| ABSTRACT | An approach to printing a nickel precursor ink on a wide range of substrates for electronics and magnetic applications is disclosed. The nickel ink reduces to elemental nickel following heating. The ink was printed using an ultrasonic aerosol printing technique. By sintering the nickel precursor ink in the presence of a homogeneous magnetic field, the reduced nickel complex formed continuously aligned nickel nanofibers axially aligned with the direction of the magnetic field. The fabrication of aligned interlayered nanofiber films provides opportunities to produce structures with enhanced isotropic electrical and magnetic properties. The resistivity of the film was found to be as low as 0.56 mΩ·cm, and the saturation magnetization was measured to be 30 emu/g, which is comparable to bulk Ni. Magnetic anisotropy was induced with an easy axis along the direction of the applied magnetic field with soft magnetic properties. |
| FILED | Thursday, April 18, 2019 |
| APPL NO | 16/388459 |
| ART UNIT | 2853 — Printing/Measuring and Testing |
| CURRENT CPC | Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 2/035 (20130101) Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 1/22 (20130101) Original (OR) Class B41M 7/0081 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11256806 | Haug et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Joshua Haug (Sierra Madre, California); David W. Payton (Calabasas, California) |
| ABSTRACT | A system for cyber-attack detection within cyber-physical systems (such as a vehicle). The system operates by obtaining a time-varying analog side-channel signal from components with the cyber-physical system and converting the time-varying analog side-channel signal to a digital side-channel signal. A time-series of system states are then identified based on the digital side-channel signal. The time-series of system states are compared with software states as generated by the cyber-physical system components, such that when the software states are unmatched with the time-series of system states, a side-channel is designated as having a security breach. In such an event, the cyber-physical system is then caused to implement an action based on the side-channel security breach. |
| FILED | Friday, June 21, 2019 |
| APPL NO | 16/449130 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/554 (20130101) G06F 21/566 (20130101) Original (OR) Class G06F 2221/034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11258487 | Robinson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rampart Communications, Inc. (Annapolis, Maryland) |
| ASSIGNEE(S) | Rampart Communications, Inc. (Annapolis, Maryland) |
| INVENTOR(S) | Matthew Brandon Robinson (Crownsville, Maryland) |
| ABSTRACT | A method includes generating a set of symbols based on an incoming data vector. The set of symbols includes K symbols, K being a positive integer. A first transformation matrix including an equiangular tight frame (ETF) transformation or a nearly equiangular tight frame (NETF) transformation is generated, having dimensions N×K, where N is a positive integer and has a value less than K. A second transformation matrix having dimensions K×K is generated based on the first transformation matrix. A third transformation matrix having dimensions K×K is generated by performing a series of unitary transformations on the second transformation matrix. A first data vector is transformed into a second data vector having a length N based on the third transformation matrix and the set of symbols. A signal representing the second data vector is sent to a transmitter for transmission of a signal representing the second data vector to a receiver. |
| FILED | Tuesday, June 23, 2020 |
| APPL NO | 16/909175 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Electric Digital Data Processing G06F 7/556 (20130101) Transmission H04B 7/0456 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, February 22, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/details-patents-20220222.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page