FedInvent™ Patents

Patent Details for Tuesday, March 01, 2022 

This page was updated on Thursday, March 03, 2022 at 10:09 PM GMT

Department of Health and Human Services (HHS) 

US 11259704 Zharov
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Vladimir Pavlovich Zharov (Little Rock, Arkansas)
ASSIGNEE(S) BIOVENTURES, LLC (Little Rock, Arkansas)
INVENTOR(S) Vladimir Pavlovich Zharov (Little Rock, Arkansas)
ABSTRACT A photoacoustic flow cytometry (PAFC) device for the in vivo detection of cells circulating in blood or lymphatic vessels is described. Ultrasound transducers attached to the skin of an organism detect the photoacoustic ultrasound waves emitted by target objects in response to their illumination by at least one pulse of laser energy delivered using at least one wavelength. The wavelengths of the laser light pulse may be varied to optimize the absorption of the laser energy by the target object. Target objects detected by the device may be unlabelled biological cells or cell products, contrast agents, or biological cells labeled with one or more contrast agents.
FILED Thursday, November 12, 2015
APPL NO 14/939039
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0059 (20130101)
A61B 5/0095 (20130101) Original (OR) Class
A61B 5/412 (20130101)
A61B 5/415 (20130101)
A61B 5/416 (20130101)
A61B 5/418 (20130101)
A61B 5/02007 (20130101)
A61B 5/7278 (20130101)
A61B 8/08 (20130101)
A61B 18/20 (20130101)
A61B 2018/207 (20130101)
A61B 2018/00642 (20130101)
A61B 2018/20351 (20170501)
A61B 2018/20357 (20170501)
A61B 2018/20361 (20170501)

Preparations for Medical, Dental, or Toilet Purposes
A61K 49/22 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/147 (20130101)
G01N 15/1425 (20130101)
G01N 15/1434 (20130101)
G01N 21/39 (20130101)
G01N 21/1702 (20130101)
G01N 2015/1477 (20130101)
G01N 2201/0697 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11259705 Smeltzer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) BioVentures, LLC (Little Rock, Arkansas)
ASSIGNEE(S) BioVentures, LLC (Little Rock, Arkansas)
INVENTOR(S) Mark S. Smeltzer (Little Rock, Arkansas);  Vladimir Zharov (Little Rock, Arkansas);  Ekaterina Galanzha (Little Rock, Arkansas)
ABSTRACT A method of non-invasively detecting and purging bacterial cells using a modified photoacoustic in vivo flow cytometer device is described herein. In particular, a method of detecting bacterial cells by analyzing photoacoustic pulses emitted in response to laser pulses from a pulsed laser source and/or selectively destroying the detected bacterial cells using a non-linear photothermal response induced by a high-energy laser pulse is described herein.
FILED Monday, February 11, 2019
APPL NO 16/272798
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0095 (20130101) Original (OR) Class
A61B 5/4839 (20130101)
A61B 5/14525 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 41/00 (20130101)
A61K 49/221 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/007 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/569 (20130101)
G01N 33/48728 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11259870 DiMaio et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) Intuitive Surgical Operations, Inc. (Sunnyvale, California);  The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) Intuitive Surgical Operations, Inc. (Sunnyvale, California)
INVENTOR(S) Simon P. DiMaio (San Carlos, California);  Christopher J. Hasser (Los Altos, California);  Russell H. Taylor (Severna Park, Maryland);  David Q. Larkin (Menlo Park, California);  Peter Kazanzides (Towson, Maryland);  Anton Deguet (Baltimore, Maryland);  Balazs Peter Vagvolgyi (Baltimore, Maryland);  Joshua Leven (San Francisco, California)
ABSTRACT In one embodiment of the invention, a a minimally invasive surgical system is disclosed. The system configured to capture and display camera images of a surgical site on at least one display device at a surgeon console; switch out of a following mode and into a masters-as-mice (MaM) mode; overlay a graphical user interface (GUI) including an interactive graphical object onto the camera images; and render a pointer within the camera images for user interactive control. In the following mode, the input devices of the surgeon console may couple motion into surgical instruments. In the MaM mode, the input devices interact with the GUI and interactive graphical objects. The pointer is manipulated in three dimensions by input devices having at least three degrees of freedom. Interactive graphical objects are related to physical objects in the surgical site or a function thereof and are manipulatable by the input devices.
FILED Wednesday, October 04, 2017
APPL NO 15/725271
ART UNIT 3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/00193 (20130101)
A61B 8/00 (20130101)
A61B 8/12 (20130101)
A61B 8/4245 (20130101)
A61B 34/10 (20160201) Original (OR) Class
A61B 34/25 (20160201)
A61B 34/30 (20160201)
A61B 34/37 (20160201)
A61B 34/70 (20160201)
A61B 34/71 (20160201)
A61B 34/76 (20160201)
A61B 90/361 (20160201)
A61B 2017/00203 (20130101)
A61B 2090/365 (20160201)
A61B 2090/378 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260024 Bronshtein
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) UNIVERSAL STABILIZATION TECHNOLOGIES, INC (San Diego, California)
ASSIGNEE(S) UNIVERSAL STABILIZATION TECHNOLOGIES, INC (San Diego, California)
INVENTOR(S) Victor Bronshtein (San Diego, California)
ABSTRACT Biopharmaceuticals, such as vaccine agents and probiotics, are encapsulated in carbohydrate-glass particles and embedded in an amorphous polymer substrate to produce polymeric compositions containing ambient-temperature stable biopharmaceuticals for syringeless administration to patients such as via dissolvable films, micro-needle patches and similar medical delivery devices. The amorphous polymer substrate is soluble in both water and a volatile organic solvent, yet the carbohydrate-glass particles are insoluble in the volatile organic solvent.
FILED Thursday, March 28, 2019
APPL NO 16/368757
ART UNIT 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0021 (20130101) Original (OR) Class
A61K 35/741 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260043 McAllister et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Sutter Bay Hospitals (San Francisco, California)
ASSIGNEE(S) SUTTER BAY HOSPITALS (San Francisco, California)
INVENTOR(S) Sean D. McAllister (San Francisco, California);  Pierre-Yves Desprez (Richmond, California)
ABSTRACT This disclosure provides compositions and method useful for treating cell proliferative disorders including cancer. The disclosure provides cannabidiol derivatives and compositions thereof either alone or in combination with THC or a derivative thereof.
FILED Wednesday, December 31, 2014
APPL NO 14/587831
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/05 (20130101)
A61K 31/35 (20130101)
A61K 31/352 (20130101) Original (OR) Class
A61K 45/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260058 Gallo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Richard L. Gallo (San Diego, California);  Teruaki Nakatsuji (San Diego, California)
ABSTRACT The disclosure provides for compounds of the general structure:
and methods of using and compositions comprising the compounds for treating infections, cancer and neoplastic diseases and disorders.
FILED Tuesday, March 27, 2018
APPL NO 16/497430
ART UNIT 1699 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/0014 (20130101)
A61K 31/52 (20130101) Original (OR) Class
A61K 35/741 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/00 (20180101)
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260073 Prakash et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) IONIS PHARMACEUTICALS, INC. (Carlsbad, California);  BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) IONIS PHARMACEUTICALS, INC. (Carlsbad, California);  BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Thazha P. Prakash (Carlsbad, California);  Frank Rigo (Carlsbad, California);  David Corey (Dallas, Texas)
ABSTRACT Disclosed herein are compounds and methods for modulating C9orf72 transcript. Such compounds and methods are useful to treat, prevent, or ameliorate neurodegenerative diseases in an individual in need thereof.
FILED Wednesday, November 02, 2016
APPL NO 15/772805
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/712 (20130101) Original (OR) Class
A61K 31/7115 (20130101)
A61K 31/7125 (20130101)
A61K 48/0066 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 21/00 (20180101)
A61P 25/28 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 2310/14 (20130101)
C12N 2310/113 (20130101)
C12N 2310/321 (20130101)
C12N 2310/321 (20130101)
C12N 2310/322 (20130101)
C12N 2310/345 (20130101)
C12N 2310/346 (20130101)
C12N 2310/3521 (20130101)
C12N 2310/3525 (20130101)
C12N 2310/3533 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 2600/178 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260083 Reddy
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Pavan Reddy (Ann Arbor, Michigan)
ABSTRACT Provided herein are compositions and methods for administering bacterial strains to reduce GvHD and improve survival after allogeneic BMT.
FILED Wednesday, March 15, 2017
APPL NO 16/085090
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/19 (20130101)
A61K 9/48 (20130101)
A61K 9/0053 (20130101)
A61K 35/742 (20130101) Original (OR) Class
A61K 2035/115 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 37/06 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260086 Fichorova et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts)
ASSIGNEE(S) THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts)
INVENTOR(S) Raina Fichorova (Chestnut Hill, Massachusetts);  Andrew Onderdonk (Westwood, Massachusetts);  Hidemi Yamamoto (Medford, Massachusetts);  Mary Delaney (Belmont, Massachusetts);  Andrea Dubois (Roslindale, Massachusetts)
ABSTRACT Described herein are methods and compositions for the use of treating and/or preventing vaginal bacterial infection and promoting healthy vaginal flora. Aspects of the invention relate to administering to a subject in need thereof a composition comprising a bacterial mixture of L. crispatus, L. gasseri, and L. jensenii.
FILED Tuesday, July 11, 2017
APPL NO 16/307857
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/0034 (20130101)
A61K 31/4164 (20130101)
A61K 31/7016 (20130101)
A61K 31/7056 (20130101)
A61K 31/7076 (20130101)
A61K 31/7076 (20130101)
A61K 35/747 (20130101) Original (OR) Class
A61K 35/747 (20130101)
A61K 45/06 (20130101)
A61K 2035/115 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/20 (20130101)
C12N 1/205 (20210501)

Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms
C12R 2001/225 (20210501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260089 Rohwer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) SAN DIEGO STATE UNIVERSITY (SDSU) FOUNDATION (San Diego, California);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) SAN DIEGO STATE UNIVERSITY (SDSU) FOUNDATION (San Diego, California);  THE REGENTS OF THE UNIVERSITY OE CALIFORNIA (Oakland, California)
INVENTOR(S) Forest Rohwer (San Diego, California);  Jeremy J. Barr (San Diego, California);  J. Bruce German (San Diego, California)
ABSTRACT Provided are compositions and methods for treating, ameliorating and preventing various infections, disorders and conditions in mammals, including genetically-predisposed and chronic disorders, where a microbial or bacterial flora is at least one causative or symptom-producing factor, where exemplary compositions are products of manufacture, a food, a drink, a nutraceutical, a dietary supplement, a formulation, a pharmaceutical or a pharmaceutical preparation comprising at least one or several of a plurality of isolated, or substantially purified bacteriophages or prophages, or bacteriophage subunits, a milk, a milk product, milk lipid, milk fat globule (MFG) macromolecule, a milk mucin, a milk glycolipid, a milk free glycan, a milk mucin-like glycoprotein, a milk protein, a milk sugar or lactose, a milk fat or butterfat, a milk vitamin. In alternative embodiment, provided are compositions and methods for treating, preventing or ameliorating an infection, for example, an infection in the gastrointestinal tract, or bowel.
FILED Wednesday, November 18, 2015
APPL NO 15/528354
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Dairy Products, e.g Milk, Butter, Cheese; Milk or Cheese Substitutes; Making Thereof
A23C 7/04 (20130101)
A23C 9/152 (20130101)
A23C 9/158 (20130101)
A23C 9/206 (20130101)
A23C 13/12 (20130101)

Fodder
A23K 20/10 (20160501)

Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 2/52 (20130101)
A23L 33/10 (20160801)
A23L 33/40 (20160801)

Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages
A23V 2002/00 (20130101)
A23V 2002/00 (20130101)
A23V 2200/324 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 35/76 (20130101) Original (OR) Class
A61K 45/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260090 Bruce et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) University of Vermont and State Agricultural College (Burlington, Vermont)
ASSIGNEE(S) University of Vermont and State Agricultural College (Burlington, Vermont)
INVENTOR(S) Emily Adaline Bruce (Hinesburg, Vermont);  Jason William Botten (Williston, Vermont);  Christopher Michael Ziegler (Winooski, Vermont)
ABSTRACT Provided are modified arenaviruses and populations thereof, wherein the modified arenaviruses include i) an introduced PPXY domain; ii) an increased number of PPXY domains; iii) a substituted amino acid in place of S41 in a viral Z protein that is not a substrate for a serine or tyrosine kinase, or a combination of i)-iii). A PPXY domain can include a phosphomimetic replacement of the Y amino acid. Modified Old World and New World arenaviruses are included. Arenavirus production is provided using cell cultures that contain a kinase inhibitor that inhibits a kinase that can phosphorylate the Y amino acid of the PPXY domain, or by cells that have disrupted kinase gene expression, or by cells that have a disrupted ESCRT system. Also provided are pharmaceutical formulations that contain modified arenaviruses, and methods of using such formulations for stimulating an immune response hat is fully or partially protective against arenavirus infection.
FILED Wednesday, March 08, 2017
APPL NO 16/082768
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/76 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 37/04 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 2760/10021 (20130101)
C12N 2760/10022 (20130101)
C12N 2760/10023 (20130101)
C12N 2760/10032 (20130101)
C12N 2760/10051 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260092 Orbach et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
ASSIGNEE(S) Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S) Marc J. Orbach (Tucson, Arizona);  Lisa F. Shubitz (Tuscon, Arizona);  Hema P. Narra (Tucson, Arizona)
ABSTRACT The present disclosure provides immunogenic materials and methods useful for reducing the risk of fungal infections, particularly valley fever. The disclosure also provides assays for identifying compounds useful to treat valley fever, as well as methods for ameliorating the symptoms of valley fever.
FILED Monday, August 31, 2020
APPL NO 17/007384
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 36/06 (20130101) Original (OR) Class
A61K 39/0002 (20130101)
A61K 2039/54 (20130101)
A61K 2039/55 (20130101)
A61K 2039/522 (20130101)
A61K 2039/543 (20130101)
A61K 2039/545 (20130101)
A61K 2039/552 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 2310/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260120 Aman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) INTEGRATED BIOTHERAPEUTIC VACCINES, INC. (Rockville, Maryland)
ASSIGNEE(S) INTEGRATED BIOTHERAPEUTIC VACCINES, INC. (Rockville, Maryland)
INVENTOR(S) Mohammad Javad Aman (Rockville, Maryland);  Thomas Kort (Rockville, Maryland);  Arundhathi Venkatasubramaniam (Rockville, Maryland);  Nils Williston (Rockville, Maryland);  Rajan Prasad Adhikari (Rockville, Maryland);  Frederick W. Holtsberg (Rockville, Maryland)
ABSTRACT The present disclosure provides immunogenic compositions useful in prevention and treatment of Staphylococcus aureus infection. In particular, the disclosure provides multivalent oligopeptides, fusion proteins comprising two or more staphylococcal superantigen (SAg) proteins, or any fragments, variants, or derivatives thereof fused together as a single polypeptide in any order.
FILED Wednesday, July 25, 2018
APPL NO 16/633664
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/085 (20130101) Original (OR) Class
A61K 2039/53 (20130101)
A61K 2039/70 (20130101)
A61K 2039/55505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/70 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260121 Steinmetz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Nicole F. Steinmetz (Cleveland, Ohio);  Amy M. Wen (Cleveland, Ohio);  Steven Fiering (Cleveland, Ohio);  Patrick H. Lizotte (Cleveland, Ohio)
ABSTRACT A method of treating cancer in a subject in need thereof includes administering in situ to the cancer a therapeutically effective amount of a virus or virus-like particle.
FILED Friday, April 17, 2020
APPL NO 16/851778
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/704 (20130101)
A61K 39/12 (20130101) Original (OR) Class
A61K 2039/544 (20130101)
A61K 2039/585 (20130101)
A61K 2039/5258 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
A61P 35/04 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2770/00023 (20130101)
C12N 2770/00034 (20130101)
C12N 2770/00071 (20130101)
C12N 2770/32022 (20130101)
C12N 2770/32023 (20130101)
C12N 2770/32034 (20130101)
C12N 2770/32071 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260127 Karathanasis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Efstathios Karathanasis (Solon, Ohio);  Watuthentrige Pubudu M. Peiris (Twinsburg, Ohio);  Vindya Perera (Hudson, Ohio);  Lisa Bauer (Sandusky, Ohio)
ABSTRACT A system for delivering a therapeutic agent to cell or tissue of a subject includes a mesoporous silica iron oxide nanoparticle with one or more therapeutic agents that are contained in a mesoporous silica layer of the nanoparticle and a remote radiofrequency (RF) energy source for applying RF energy to the nanoparticle effective to release the one or more therapeutic agents from the nanoparticle by mechanical tumbling and/or vibration of the nanoparticle, wherein release of the one or more therapeutic agents not caused by a hyperthermic response of the nanoparticle to the RF energy.
FILED Wednesday, October 17, 2018
APPL NO 16/163211
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0009 (20130101)
A61K 9/0019 (20130101)
A61K 9/5115 (20130101)
A61K 31/495 (20130101)
A61K 31/519 (20130101)
A61K 31/704 (20130101)
A61K 31/7068 (20130101)
A61K 41/0028 (20130101) Original (OR) Class
A61K 47/6923 (20170801)
A61K 47/6929 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
A61P 35/04 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260132 Moses et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Children's Medical Center Corporation (Boston, Massachusetts)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S) Marsha A. Moses (Brookline, Massachusetts);  Peng Guo (Boston, Massachusetts);  Jiang Yang (West Lafayette, Indiana);  Debra Auguste (Briarcliff Manor, New York);  Daxing Liu (Stony Brook, New York)
ABSTRACT The disclosure provides liposomes (e.g., cancer-targeting liposomes) with ligands (e.g., EGFR ligands and ICAM-1 ligands) conjugated to liposome surfaces. In some embodiments, the molecular ratio of different ligands complement the relative molecular density (i.e., ratio) of overexpressed protein on the surface of a cell targeted by the liposome (e.g., cancer cell).
FILED Friday, March 16, 2018
APPL NO 16/494551
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/704 (20130101)
A61K 47/6849 (20170801)
A61K 47/6855 (20170801)
A61K 47/6913 (20170801) Original (OR) Class
A61K 47/6915 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
A61P 35/04 (20180101)

Peptides
C07K 16/2821 (20130101)
C07K 16/2863 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260133 Ruoslahti et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Erkki Ruoslahti (Buellton, California);  Tambet Teesalu (Goleta, California);  Kazuki Sugahara (Goleta, California)
ASSIGNEE(S) SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (La Jolla, California)
INVENTOR(S) Erkki Ruoslahti (Buellton, California);  Tambet Teesalu (Goleta, California);  Kazuki Sugahara (Goleta, California)
ABSTRACT Disclosed are compositions and methods useful for targeting and internalizing molecules into cells of interest and for penetration by molecules of tissues of interest. The compositions and methods are based on peptide sequences that are selectively internalized by a cell, penetrate tissue, or both. The disclosed internalization and tissue penetration is useful for delivering therapeutic and detectable agents to cells and tissues of interest.
FILED Friday, February 20, 2009
APPL NO 12/390061
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/62 (20170801)
A61K 47/64 (20170801)
A61K 47/6923 (20170801) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260147 Romero-Ortega et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Mario I. Romero-Ortega (Coppell, Texas);  Parisa Lotfi (Houston, Texas);  Benjamin R Johnston (Arlington, Texas);  Swarupnarayan Dash (Arlington, Texas);  Joselito Razal (Wollongong, Australia);  Gordon Wallace (Wollongong, Australia)
ABSTRACT In one aspect, apparatuses for providing chemical gradients are described herein. In some embodiments, an apparatus described herein comprises a conduit having a first end and a second end, one or more microchannels disposed in the conduit and extending from the first end toward the second end, and a fiber coiled around the exterior of at least one microchannel, wherein the fiber comprises an active agent that is operable to diffuse into the interior of the microchannel.
FILED Monday, May 11, 2020
APPL NO 16/871857
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/18 (20130101) Original (OR) Class
A61L 27/18 (20130101)
A61L 27/20 (20130101)
A61L 27/20 (20130101)
A61L 27/54 (20130101)
A61L 27/58 (20130101)
A61L 2430/32 (20130101)

Compositions of Macromolecular Compounds
C08L 5/12 (20130101)
C08L 67/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260174 Patel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Beta Bionics, Inc. (Irvine, California)
ASSIGNEE(S) Beta Bionics, Inc. (Irvine, California)
INVENTOR(S) Himanshu Patel (Rancho Santa Margarita, California);  Edward R. Damiano (Acton, Massachusetts);  Firas H. El-Khatib (Allston, Massachusetts);  Michael J. Rosinko (Anaheim, California)
ABSTRACT Systems and methods presented herein relate to managing ambulatory medical device data access. A computing system of a networked computing environment can establish a direct end-to-end data connection to an ambulatory medical device via a wireless wide area network. A public key of the computing system may be transmitted to the ambulatory medical device permitting the ambulatory medical device to encrypt data to be transmitted to the computing system. The computing system may receive, via the direct end-to-end data connection, encrypted data from the ambulatory medical device, and upon decrypting the data can generate a therapy report based at least in part on the therapy data. This therapy report may include time-series therapy data relating to the therapy delivered by the ambulatory medical device over a particular time period. The computing system can restrict access to the therapy report to authorized users.
FILED Friday, October 02, 2020
APPL NO 17/062319
ART UNIT 2434 — Cryptography and Security
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/14532 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/142 (20130101)
A61M 5/172 (20130101) Original (OR) Class
A61M 5/1723 (20130101)
A61M 5/14244 (20130101)
A61M 5/14248 (20130101)
A61M 5/16831 (20130101)
A61M 2005/1726 (20130101)
A61M 2005/14208 (20130101)
A61M 2205/18 (20130101)
A61M 2205/50 (20130101)
A61M 2205/52 (20130101)
A61M 2205/502 (20130101)
A61M 2205/505 (20130101)
A61M 2205/581 (20130101)
A61M 2205/582 (20130101)
A61M 2205/583 (20130101)
A61M 2205/609 (20130101)
A61M 2205/3327 (20130101)
A61M 2205/3546 (20130101)
A61M 2205/3553 (20130101)
A61M 2205/3584 (20130101)
A61M 2205/3592 (20130101)
A61M 2230/201 (20130101)

Electric Digital Data Processing
G06F 3/04847 (20130101)
G06F 3/04883 (20130101)
G06F 8/61 (20130101)
G06F 8/65 (20130101)
G06F 8/656 (20180201)
G06F 21/31 (20130101)
G06F 21/84 (20130101)
G06F 21/305 (20130101)
G06F 21/6245 (20130101)

Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 21/18 (20130101)
G08B 21/0453 (20130101)
G08B 25/00 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 10/60 (20180101)
G16H 20/17 (20180101)
G16H 40/00 (20180101)
G16H 40/40 (20180101)
G16H 40/60 (20180101)
G16H 40/67 (20180101)
G16H 50/30 (20180101)
G16H 80/00 (20180101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/30 (20130101)
H04L 9/088 (20130101)
H04L 63/101 (20130101)
H04L 67/34 (20130101)

Wireless Communication Networks
H04W 76/10 (20180201)
H04W 76/14 (20180201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260358 Lee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Daeyeon Lee (Wynnewood, Pennsylvania);  Kathleen J. Stebe (Penn Valley, Pennsylvania);  Sarah D. Hann (Yardley, Pennsylvania)
ABSTRACT In one aspects of the invention, a microcapsule includes a film encapsulating a material. The film is formed by complexation of at least two mutually attractive components initially present in an aqueous dispersion comprising a continuous phase and a dispersed phase. The at least one first component is initially present in the continuous phase and the at least one second component is initially present in the dispersed phase. According to another aspect of the invention, provided is a process for forming microcapsules including the step of injecting a dispersed phase having at least a first component into a continuous phase having at least a second component, where the first component and the second component are mutually attractive, such that a film is formed by complexation of the first charged component and the second charged component.
FILED Friday, April 13, 2018
APPL NO 15/952321
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5031 (20130101)
A61K 9/5036 (20130101)
A61K 35/74 (20130101)
A61K 2035/128 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 13/04 (20130101)
B01J 13/10 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 11/04 (20130101)
C12N 11/10 (20130101)
C12N 11/082 (20200101)
C12N 11/087 (20200101)
C12N 11/089 (20200101)
C12N 11/098 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260424 Ma et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California)
INVENTOR(S) Bo Ma (Palo Alto, California);  Jose Joseph (Stanford, California);  Kamyar Firouzi (Palo Alto, California);  Butrus T. Khuri-Yakub (Palo Alto, California)
ABSTRACT Aspects of this disclosure relate to a capacitive micromachined ultrasonic transducer (CMUT) with a contoured electrode. In certain embodiments, the CMUT has a contoured electrode. The electrode may be non-planar to correspond to a deflected shape of the outer plate. A change in distance between the electrode and the plate after deflection may be greater than a minimum threshold across the width of the CMUT.
FILED Tuesday, January 19, 2021
APPL NO 17/152555
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General
B06B 1/0215 (20130101) Original (OR) Class
B06B 1/0292 (20130101)
B06B 1/0651 (20130101)
B06B 1/0662 (20130101)
B06B 2201/55 (20130101)

Microstructural Devices or Systems, e.g Micromechanical Devices
B81B 3/0021 (20130101)
B81B 2201/0271 (20130101)
B81B 2203/04 (20130101)

Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems
B81C 1/00166 (20130101)
B81C 2201/0157 (20130101)
B81C 2201/0178 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/22 (20130101)
G01N 29/0654 (20130101)
G01N 29/2406 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261152 Rettig et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of California (Oakland, California);  The United States Government represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Matthew Rettig (Los Angeles, California);  Michael E. Jung (Los Angeles, California);  D. Elshan Nakath G. Ralalage (Los Angeles, California);  Jiabin An (Los Angeles, California)
ABSTRACT The present disclosure provides compounds and methods for inhibiting or degrading the N-terminal domain of the androgen receptor, as well as methods for treating cancers such as prostate cancer.
FILED Friday, January 19, 2018
APPL NO 16/478914
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Acyclic or Carbocyclic Compounds
C07C 33/486 (20130101)
C07C 49/223 (20130101)
C07C 225/16 (20130101) Original (OR) Class
C07C 235/34 (20130101)
C07C 235/78 (20130101)
C07C 321/20 (20130101)

Heterocyclic Compounds
C07D 207/08 (20130101)
C07D 211/32 (20130101)
C07D 241/04 (20130101)
C07D 265/30 (20130101)
C07D 303/32 (20130101)
C07D 303/40 (20130101)
C07D 307/52 (20130101)
C07D 333/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261157 Batchelor et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) NovaTarg, Inc. (Research Triangle Park, North Carolina)
ASSIGNEE(S) NovaTarg, Inc. (Research Triangle Park, North Carolina)
INVENTOR(S) Kenneth Batchelor (Wilmington, North Carolina);  Jeffery E. Cobb (Chapel Hill, North Carolina);  Kristjan S. Gudmundsson (Raleigh, North Carolina);  Brad R. Henke (Cary, North Carolina);  Francis X. Tavares (Durham, North Carolina)
ABSTRACT The present invention provides novel fused bicyclic alkylene linked imidodicarbonimidic diamides. In particular, described herein are N-[2-(indol-3-yl)alkylene]-linked imidodicarbonimidic diamides and N-[2-(pyrrolopyridin-3-yl)alkylene]-linked imidodicarbonimidic diamides (compound of formula (I) or formula (II)), and uses therefor. The compounds of the present invention are believed to be organic cation transporter selective compounds, useful for the treatment of diseases and conditions caused by reduced activity of 5′ adenosine monophosphate-activated protein kinase (AMPK).
FILED Thursday, December 07, 2017
APPL NO 16/467136
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 3/10 (20180101)

Heterocyclic Compounds
C07D 209/20 (20130101) Original (OR) Class
C07D 209/32 (20130101)
C07D 471/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261162 Bozik et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Knopp Biosciences LLC (Pittsburgh, Pennsylvania)
ASSIGNEE(S) KNOPP BIOSCIENCES, LLC (Pittsburgh, Pennsylvania)
INVENTOR(S) Michael E. Bozik (Wexford, Pennsylvania);  Scott S. Harried (Sun Prairie, Wisconsin);  Lynn Resnick (Pittsburgh, Pennsylvania);  George T. Topalov (Pittsburgh, Pennsylvania);  Justin K. Belardi (Pittsburgh, Pennsylvania);  Charles A. Flentge (Mars, Pennsylvania);  David A. Mareska (McMurray, Pennsylvania);  James S. Hale (Pittsburgh, Pennsylvania)
ABSTRACT Provided herein are optionally substituted benzoimidazol-1,2-yl amides, pharmaceutical compositions comprising a therapeutically effective amount of such compounds and a pharmaceutically acceptable excipient, and methods of treating Kv7 associated diseases, such as, epilepsy, amyotrophic lateral sclerosis, various types of pain, hyperexcitability, a dyskinesia, dystonia, mania and tinnitus with such compounds and pharmaceutical compositions.
FILED Thursday, October 22, 2020
APPL NO 17/077068
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 235/30 (20130101) Original (OR) Class
C07D 405/04 (20130101)
C07D 471/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261201 Kahne et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Daniel E. Kahne (Brookline, Massachusetts);  Vadim Baidin (Cambridge, Massachusetts)
ABSTRACT Disclosed herein are secondary amine compounds that inhibit tRNA synthetase. The compounds of the invention are useful in inhibiting tRNA synthetase in Gram-negative bacteria and are useful in killing Gram-negative bacteria. The secondary amine compounds of the invention are also useful in the treatment of tuberculosis.
FILED Friday, January 11, 2019
APPL NO 16/961516
ART UNIT 1699 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)

Acyclic or Carbocyclic Compounds
C07C 211/27 (20130101)
C07C 211/40 (20130101)
C07C 215/28 (20130101)

Heterocyclic Compounds
C07D 209/04 (20130101)
C07D 213/38 (20130101)
C07D 213/643 (20130101)
C07D 215/06 (20130101)
C07D 215/12 (20130101)
C07D 221/04 (20130101)
C07D 221/20 (20130101)
C07D 231/12 (20130101)
C07D 231/56 (20130101)
C07D 239/26 (20130101)
C07D 239/34 (20130101)
C07D 261/08 (20130101)
C07D 267/10 (20130101)
C07D 295/13 (20130101)
C07D 307/14 (20130101)
C07D 307/79 (20130101)
C07D 307/87 (20130101)
C07D 309/04 (20130101)
C07D 311/74 (20130101)
C07D 317/58 (20130101)
C07D 319/08 (20130101)
C07D 327/06 (20130101)
C07D 471/04 (20130101)
C07D 471/08 (20130101)
C07D 493/08 (20130101)
C07D 495/04 (20130101)
C07D 498/08 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 5/027 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261208 Morrow et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) The Research Foundation for The State University of New York (Buffalo, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Amherst, New York)
INVENTOR(S) Janet R. Morrow (Williamsville, New York);  Eric M. Snyder (Williamsville, New York);  Didar Asik (Buffalo, New York)
ABSTRACT Provided are macrocyclic compounds and compounds with two or more macrocyclic groups, iron coordinated macrocyclic compounds, and iron coordinated compounds with two or more macrocyclic groups. The iron is high-spin iron(III). The iron coordinated compounds may exhibit a negative redox potential (e.g., relative to a normal hydrogen electrode at a biologically relevant pH, for example, a pH of 6.5-7.5). The compounds can be used as MRI contrast agents.
FILED Monday, May 21, 2018
APPL NO 16/615024
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/085 (20130101)
A61K 49/106 (20130101)
A61K 49/124 (20130101)
A61K 49/128 (20130101)
A61K 49/143 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 15/025 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261226 Irvine et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (MITN1) (Cambridge, Massachusetts)
INVENTOR(S) Darrell J. Irvine (Arlington, Massachusetts);  Yiran Zheng (Cambridge, Massachusetts);  Li Tang (Quincy, Massachusetts)
ABSTRACT The present disclosure is directed, in some embodiments, to methods and compositions of comprising a cell having a non-internalizing receptor, and a nanoparticle surface-modified with a ligand that binds to the non-internalizing receptor.
FILED Wednesday, May 12, 2021
APPL NO 17/318590
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/127 (20130101)
A61K 39/0011 (20130101)
A61K 39/001104 (20180801)
A61K 47/60 (20170801)
A61K 47/6849 (20170801)
A61K 47/6889 (20170801)
A61K 47/6903 (20170801)
A61K 47/6913 (20170801)
A61K 2039/57 (20130101)
A61K 2039/505 (20130101)
A61K 2039/585 (20130101)
A61K 2039/5156 (20130101)
A61K 2039/5158 (20130101)
A61K 2039/55527 (20130101)
A61K 2039/55533 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/55 (20130101) Original (OR) Class
C07K 14/5443 (20130101)
C07K 14/7051 (20130101)
C07K 14/7155 (20130101)
C07K 14/70503 (20130101)
C07K 14/70517 (20130101)
C07K 14/70578 (20130101)
C07K 14/70589 (20130101)
C07K 16/30 (20130101)
C07K 16/289 (20130101)
C07K 16/2806 (20130101)
C07K 16/2845 (20130101)
C07K 19/00 (20130101)
C07K 2317/622 (20130101)
C07K 2319/00 (20130101)
C07K 2319/03 (20130101)
C07K 2319/30 (20130101)
C07K 2319/33 (20130101)
C07K 2319/70 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0006 (20130101)
C12N 5/0636 (20130101)
C12N 5/0638 (20130101)
C12N 2501/2315 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261232 Boice et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S) MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York)
INVENTOR(S) Michael Henry Boice (San Mateo, California);  Hans Guido Wendel (New York, New York);  Darin Salloum (New York, New York)
ABSTRACT In some aspects the present invention provides methods for the treatment of B-cell lymphomas. Some such methods involve administration of HVEM ectodomain polypeptides, anti-HVEM antibodies, or anti-BTLA antibodies to subjects in need thereof. Some such methods involve use of CAR T cells, such as CD19-specific CAR T cells. The present invention also provides compositions useful in such methods. These and other embodiments of the present invention and described further herein.
FILED Monday, April 04, 2016
APPL NO 15/563666
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 38/1793 (20130101)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/7051 (20130101)
C07K 14/70521 (20130101)
C07K 14/70578 (20130101) Original (OR) Class
C07K 16/2803 (20130101)
C07K 2319/03 (20130101)
C07K 2319/33 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101)
C12N 2510/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261234 Xiao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) IVYGEN CORPORATION (Fort Washington, Pennsylvania)
ASSIGNEE(S) IVYGEN CORPORATION (Fort Washington, Pennsylvania)
INVENTOR(S) Weidong Xiao (Fort Washington, Pennsylvania);  Wenjing Cao (Ardmore, Pennsylvania);  Biao Dong (Philadelphia, Pennsylvania)
ABSTRACT In one aspect, present invention provides a recombinant mutant human factor VIII having increased expression and/or secretion as compared to wild-type factor VIII. In certain embodiments, the recombinant factor VIII includes one or more amino acid substitution(s) selected from the group consisting of I86, Y105, A108, D115, Q117, F129, G132, H134, M147 and L152. In other aspects, the present invention provides FVIII encoding nucleic acids, FVIII-expression vectors, as well as methods of using the modified FVIII genes in the treatment of FVIII deficiencies, such as hemophilia A.
FILED Thursday, October 18, 2018
APPL NO 16/164208
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 14/755 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261235 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
ASSIGNEE(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S) Mei Chen (Altadena, California);  David Woodley (Altadena, California)
ABSTRACT The present invention discloses a method for treating wounds and for accelerating the healing of wounds by administering an effective amount of a pharmaceutical composition containing type VII collagen protein, mini-C7 protein, variants thereof or any combinations thereof. The pharmaceutical composition may be administered through a variety of routes including intravenous injection, topical application, or oral ingestion. The method may further include administering a genetically modified fibroblast capable of expressing type VII collagen protein, miniC7 protein, variants thereof or small growth factors to achieve synergistic healing effect.
FILED Wednesday, June 03, 2020
APPL NO 16/891413
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/70 (20130101)
A61K 38/39 (20130101)

Peptides
C07K 14/78 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261237 Henkin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Northwestern University (Evanston, Illinois);  Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) Northwestern University (Evanston, Illinois);  Board of Regents of the University of Nebraska (Omaha, Nebraska)
INVENTOR(S) Jack Henkin (Highland Park, Illinois);  Olga Volpert (Wilmette, Illinois);  Serguei Vinogradov (Omaha, Nebraska);  Ignacio Melgar-Asensio (Chicago, Illinois)
ABSTRACT Disclosed are modified pigment epithelium-derived factor (PEDF) peptides, particulate carrier prodrugs thereof, and pharmaceutical compositions comprising the peptides or particulate carrier prodrugs. The peptides, particulate carrier prodrugs, and pharmaceutical compositions may be used to treat diseases and disorders that are amenable to treatment with anti-angiogenic agents, anti-tumorigenic agents, anti-fibrotic agents, chemotherapy-protecting agents, and immune stimulating agents.
FILED Thursday, September 06, 2018
APPL NO 16/123863
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 47/54 (20170801)
A61K 47/55 (20170801)
A61K 47/61 (20170801)
A61K 47/64 (20170801)
A61K 47/542 (20170801)
A61K 47/6903 (20170801)
A61K 47/6921 (20170801)
A61K 47/6935 (20170801)
A61K 47/6939 (20170801)

Peptides
C07K 7/06 (20130101)
C07K 14/8121 (20130101) Original (OR) Class
C07K 19/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261250 Bernstein et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Fred Hutchinson Cancer Research Center (Seattle, Washington);  The Board of Trustees of The Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington);  THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California)
INVENTOR(S) Irwin Bernstein (Seattle, Washington);  Vincent Luca (Palo Alto, California);  Kenan Christopher Garcia (Menlo Park, California)
ABSTRACT This disclosure provides compositions and related methods providing targeted cell-specific inhibition of Notch receptor signaling. The disclosure provides a bi-specific molecule with separate domains that target the intended cell-type and the Notch receptor on that cell-type. The disclosure also provides for nucleic acids, vectors, and cells allowing for the expression of the bi-specific fusion molecules. The disclosure also provides related methods of making and using the bi-specific fusion molecule to inhibit Notch signaling in target cells of interest, including for the treatment of diseases characterized by a dysregulation of Notch signaling.
FILED Thursday, July 20, 2017
APPL NO 16/318313
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/475 (20130101)
C07K 14/705 (20130101)
C07K 14/70596 (20130101)
C07K 16/22 (20130101)
C07K 16/46 (20130101)
C07K 16/2803 (20130101) Original (OR) Class
C07K 16/2896 (20130101)
C07K 19/00 (20130101)
C07K 2317/31 (20130101)
C07K 2317/70 (20130101)
C07K 2317/76 (20130101)
C07K 2317/622 (20130101)
C07K 2319/00 (20130101)
C07K 2319/74 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/10 (20130101)
C12N 15/63 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/566 (20130101)
G01N 33/574 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261253 Zang
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York)
ASSIGNEE(S) Albert Einstein College of Medicine (Bronx, New York)
INVENTOR(S) Xingxing Zang (New York, New York)
ABSTRACT Provided are methods of treating an autoimmune disease in a subject, or of suppressing transplant rejection in a subject, or of treating a cancer in a subject, as well as compositions therefor.
FILED Wednesday, September 05, 2018
APPL NO 16/121771
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 16/2827 (20130101) Original (OR) Class
C07K 2317/21 (20130101)
C07K 2317/24 (20130101)
C07K 2319/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261256 Marasco
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
ASSIGNEE(S) DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
INVENTOR(S) Wayne A. Marasco (Wellesley, Massachusetts)
ABSTRACT The present disclosure provides methods of modulating regulatory T-cell activity and function.
FILED Monday, February 10, 2020
APPL NO 16/786798
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0011 (20130101)
A61K 39/39541 (20130101)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/2866 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/31 (20130101)
C07K 2317/52 (20130101)
C07K 2317/73 (20130101)
C07K 2317/76 (20130101)
C07K 2317/565 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261413 Vunjak-Novakovic et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Gordana Vunjak-Novakovic (New York, New York);  Keith Yeager (Jersey City, New Jersey);  Kacey Ronaldson (New York, New York);  Stephen Ma (New York, New York);  Timothy Chen (New York, New York)
ABSTRACT A bioreactor is provided that permits engineering of multiple different tissues. The bioreactor has a series of flow paths that permit application of tissue-specific media while simultaneously innervating the various different tissues with a common media. The flow paths for the various medias are designed to prevent mixing of the various media as they simultaneously innervate the tissue.
FILED Friday, January 11, 2019
APPL NO 16/246007
ART UNIT 1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 1/34 (20130101)
C12M 21/08 (20130101) Original (OR) Class
C12M 23/12 (20130101)
C12M 23/16 (20130101)
C12M 23/44 (20130101)
C12M 29/04 (20130101)
C12M 35/02 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/02 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261430 Daley et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
INVENTOR(S) George Q. Daley (Weston, Massachusetts);  Ryohichi Sugimura (Boston, Massachusetts)
ABSTRACT Embodiments herein relate to in vitro production methods of hematopoietic stem cell (HSC) and hematopoietic stem and progenitor cell (HSPC) that have long-term multilineage hematopoiesis potentials upon in vivo engraftment. The HSC and HSPCs are derived from pluripotent stem cells-derived hemogenic endothelia cells (HE).
FILED Wednesday, May 03, 2017
APPL NO 16/098359
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/28 (20130101)
A61K 35/44 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0647 (20130101) Original (OR) Class
C12N 15/63 (20130101)
C12N 2501/60 (20130101)
C12N 2506/02 (20130101)
C12N 2510/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261432 Soo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) B. Chia Soo (Beverly Hills, California);  Kang Ting (Beverly Hills, California);  Zhong Zheng (Van Nuys, California)
ABSTRACT The present invention provides a method of treating a disorder using a fibromodulin (FMOD) reprogrammed (FReP) cell. The method comprises administering locally to a human being the FReP cell to a site in need thereof of the human being.
FILED Monday, December 19, 2016
APPL NO 15/383917
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/00 (20130101)
A61K 35/12 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0607 (20130101)
C12N 5/0618 (20130101)
C12N 5/0653 (20130101)
C12N 5/0696 (20130101) Original (OR) Class
C12N 2506/1307 (20130101)
C12N 2510/00 (20130101)
C12N 2533/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261439 Chavez et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Alejandro Chavez (Sharon, Massachusetts);  Johnny Hao Hu (Cambridge, Massachusetts)
ABSTRACT A nucleic acid construct is provided that encodes two or more or a plurality of spacer sequences separated by restriction endonuclease recognition site. A plurality of such nucleic acid sequences are provided as a library for making guide RNAs for use with CRISPR/Cas systems.
FILED Friday, September 16, 2016
APPL NO 15/760372
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/102 (20130101)
C12N 15/1093 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261460 Byrne et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S) Barry John Byrne (Gainesville, Florida);  Darin J. Falk (Gainesville, Florida);  Christina Pacak (Gainesville, Florida);  Lara Robert DeRuisseau (Syracuse, New York);  Cathryn Mah (Irvine, California);  David D. Fuller (Gainesville, Florida)
ABSTRACT The present invention provides compositions and methods of use pertaining to rAAV-mediated delivery of therapeutically effective molecules for treatment of diseases such as Pompe disease. These compositions in combination with various routes and methods of administration result in targeted expression of therapeutic molecules in specific organs, tissues and cells.
FILED Wednesday, January 13, 2016
APPL NO 14/994477
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 45/06 (20130101)
A61K 48/0058 (20130101)
A61K 48/0075 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101) Original (OR) Class
C12N 2710/16644 (20130101)
C12N 2750/14143 (20130101)
C12N 2750/14145 (20130101)
C12N 2750/14151 (20130101)
C12N 2810/6027 (20130101)
C12N 2830/008 (20130101)

Enzymes
C12Y 302/0102 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261461 Zheng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) TONGJI UNIVERSITY (Shanghai, China PRC);  BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska)
ASSIGNEE(S) Tongji University (Shanghai, China PRC);  Board of Regents of the University of Nebraska (Lincoln, Nebraska)
INVENTOR(S) Jialin Zheng (Omaha, Nebraska);  Changhai Tian (Omaha, Nebraska)
ABSTRACT Provided are methods and compositions for transdifferentiation of a somatic cell, e.g., a fibroblast to a dopaminergic precursor, Specifically, provided are induced dopaminergic (iDP) cells, or master transcription factors (TFs) therefore, methods for making iDP cells, and methods and compositions for using them in, e.g., treating neurodegenerative diseases such as Parkinson's disease.
FILED Wednesday, August 19, 2015
APPL NO 15/503649
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/12 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0619 (20130101)
C12N 15/86 (20130101) Original (OR) Class
C12N 2501/60 (20130101)
C12N 2510/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262309 Kuzmin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Advanced Cytometry Instrumentation Systems, LLC (Buffalo, New York);  The Research Foundation for The State University of New York (Amherst, New York)
ASSIGNEE(S) Advanced Cytometry Instrumentation Systems, LLC (Buffalo, New York);  The Research Foundation for The State University of New York (Amherst, New York)
INVENTOR(S) Andrey N. Kuzmin (East Amherst, New York);  Artem Pliss (Amherst, New York);  Paras N. Prasad (East Amherst, New York)
ABSTRACT Methods for determining lipid composition. The lipid(s) in a composition may include phospholipids. A method may be carried out on an individual cell. A method may compare the Raman spectrum of the portion of a cell with a model Raman spectrum, which does not include the lipid component, where the difference between the Raman spectrum of the portion of the cell and the model Raman spectrum correlates to the lipid composition in the portion of the cell in the portion of the cell). A method may be used to diagnose a disease such as, for example, cancers, including breast cancer, prostate cancer, and via the presence and/or absence of abnormal or damaged cells in an individual.
FILED Thursday, July 11, 2019
APPL NO 16/509372
ART UNIT 2886 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/44 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/65 (20130101) Original (OR) Class
G01N 33/92 (20130101)
G01N 33/5076 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262355 Weaver et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
ASSIGNEE(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
INVENTOR(S) John B. Weaver (Hanover, New Hampshire);  Barjor Gimi (Jamaica Plain, Massachusetts);  Karl Griswold (Lyme, New Hampshire)
ABSTRACT A system for measuring analyte concentrations has porous-walled nanocontainers containing multiple magnetic nanoparticles, the magnetic nanoparticles coated with a selective binder that is analyte-responsive and binds a the analyte, an indicator substance releasable from the selective binder by the analyte, or an indicator substance cleavable by the analyte, apparatus for exposing the nanocontainers to a fluid potentially containing the analyte, and magnetic spectroscopy of Brownian motion sensing apparatus for detecting agglutination of the nanoparticles or binding of analyte to the nanoparticles. The system is used in a method comprising coating magnetic nanoparticles with a selective binder, encapsulating the magnetic nanoparticles in porous nanocontainers, exposing the nanocontainers to a fluid potentially containing analyte, using magnetic spectroscopy of Brownian motion sensing apparatus to detect agglutination or binding of the nanoparticles, and translating Brownian motion spectra to analyte concentrations.
FILED Monday, December 09, 2019
APPL NO 16/708302
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/745 (20130101)
G01N 33/54326 (20130101)
G01N 33/54366 (20130101) Original (OR) Class

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/1269 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262358 Shen-Orr et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Technion Research and Development Foundation Limited (Haifa, Israel);  The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) Technion Research and Development Foundation Limited (Haifa, Israel);  The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Shai S. Shen-Orr (Karkur, Israel);  Elina Starovetsky (Yokneam Ilit, Israel);  Naama Maimon (Nir-Etzion, Israel);  Purvesh Khatri (Menlo Park, California);  Renaud Gaujoux (Cape Town, South Africa);  Francesco Vallania (San Fransisco, California)
ABSTRACT Provided are methods of predicting responsiveness of a subject having an inflammatory bowel disease (IBD) to a tumor necrosis factor (TNF)-alpha inhibitor, by analyzing a frequency of at least one subpopulation of immune cells in a tissue biopsy of the subject. Also provided are methods of selecting a treatment for a subject and kits for determining responsiveness of the subject to treatment with a TNF-alpha inhibitor.
FILED Thursday, April 06, 2017
APPL NO 16/091988
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/158 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 30/04 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5047 (20130101)
G01N 33/56972 (20130101) Original (OR) Class
G01N 2800/52 (20130101)
G01N 2800/065 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262361 Tibbitt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Mark W. Tibbitt (Boulder, Colorado);  Kristi S. Anseth (Boulder, Colorado);  April M. Kloxin (Boulder, Colorado);  Mehmet Toner (Boulder, Colorado);  John Oakey (Boston, Massachusetts);  Ajay Shah (Boston, Massachusetts)
ABSTRACT Disclosed herein are photodegradable hydrogels and associated kits for selectively capturing and releasing cells. The hydrogels result from cross linking in the presence of a photoinitiator (1) a macromer having a polymeric backbone structure, a photo labile moiety, and a first linking moiety, and (2) a cell-binding moiety having a second linking moiety. These two components are cross-linked by a polymerization reaction of the linking moieties to form a photodegradable hydrogel incorporating the cell-binding moiety within the hydrogel. Also disclosed are methods of making the hydrogels, and methods of using the hydrogels for selectively capturing and releasing cells and for detecting cells in a fluid. Such methods can be used to detect the presence and quantity of certain rare cell types in a biological fluid.
FILED Friday, July 18, 2014
APPL NO 14/905460
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 41/0028 (20130101)
A61K 47/34 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502761 (20130101)
B01L 2200/0647 (20130101)
B01L 2300/16 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 222/22 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 47/02 (20130101)
C12M 47/04 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/531 (20130101)
G01N 33/54366 (20130101)
G01N 33/56966 (20130101)
G01N 33/57492 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262362 Wise et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S) Memorial Sloan-Kettering Cancer Center (New York, New York)
INVENTOR(S) David R. Wise (New York, New York);  Patrick S. Ward (Cambridge, Massachusetts);  Craig B. Thompson (New York, New York)
ABSTRACT The present invention provides biomarkers for sensitive, specific, accurate and quantitative diagnosis and assessment of chronic hypoxia. In particular, the present invention provides 2-hydroxyglutarate as a biomarker that is differentially produced in chronic hypoxia. Furthermore, embodiments of the invention are able to differentiate between chronic and acute hypoxia. Assays for levels of 2-hydroxyglutarate may be used alone or in conjunction with additional biomarkers of hypoxia to increase the precision of analysis. In particular embodiments of the invention, the level of 2-hydroxyglutarate and at least one second biomarker may be assayed to generate a hypoxic profile that can be compared to a reference or control profile, thereby diagnosing a subject as normoxic, chronically hypoxic, or acutely hypoxic.
FILED Sunday, November 18, 2012
APPL NO 14/359074
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/522 (20130101)
A61K 33/00 (20130101)
A61K 35/18 (20130101)
A61K 35/19 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6881 (20130101)
C12Q 1/6883 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 30/7206 (20130101)
G01N 33/5308 (20130101)
G01N 33/6893 (20130101) Original (OR) Class
G01N 2800/7038 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 49/0036 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11263444 Datta et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH Office of the Director (NIHOD)
APPLICANT(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Sandeep Robert Datta (Newton, Massachusetts);  Alexander B. Wiltschko (Somerville, Massachusetts)
ABSTRACT A method for studying the behavior of an animal in an experimental area including stimulating the animal using a stimulus device; collecting data from the animal using a data collection device; analyzing the collected data; and developing a quantitative behavioral primitive from the analyzed data. A system for studying the behavior of an animal in an experimental area including a stimulus device for stimulating the animal; a data collection device for collecting data from the animal; a device for analyzing the collected data; and a device for developing a quantitative behavioral primitive from the analyzed data. A computer implemented method, a computer system and a nontransitory computer readable storage medium related to the same. Also, a method and apparatus for automatically discovering, characterizing and classifying the behavior of an animal in an experimental area. Further, use of a depth camera and/or a touch sensitive device related to the same.
FILED Wednesday, June 13, 2018
APPL NO 16/007924
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 29/005 (20130101)
A01K 67/00 (20130101)
A01K 2227/105 (20130101)
A01K 2267/0356 (20130101)

Diagnosis; Surgery; Identification
A61B 5/112 (20130101)
A61B 5/1116 (20130101)
A61B 5/7203 (20130101)
A61B 5/7225 (20130101)
A61B 2503/40 (20130101)

Rotary-piston, or Oscillating-piston, Positive-displacement Machines for Liquids; Rotary-piston, or Oscillating-piston, Positive-displacement Pumps
F04C 2270/041 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00335 (20130101)
G06K 9/00362 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 7/0016 (20130101)
G06T 7/20 (20130101)
G06T 2207/10016 (20130101)
G06T 2207/10028 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 20/00 (20190201)

Pictorial Communication, e.g Television
H04N 13/204 (20180501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11263747 Jia et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Oregon Health and Science University (Portland, Oregon)
ASSIGNEE(S) Oregon Health and Science University (Portland, Oregon)
INVENTOR(S) Yali Jia (Portland, Oregon);  Yukun Guo (Portland, Oregon)
ABSTRACT An example method includes generating, using a multi-scale block of a convolutional neural network (CNN), a first output image based on an optical coherence tomography (OCT) reflectance image of a retina and an OCT angiography (OCTA) image of the retina. The method further includes generating, using an encoder of the CNN, at least one second output image based on the first output image and generating, using a decoder of the CNN, a third output image based on the at least one second output image. An avascular map is generated based on the third output image. The avascular map indicates at least one avascular area of the retina depicted in the OCTA image.
FILED Friday, April 24, 2020
APPL NO 16/858384
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class
G06T 9/002 (20130101)
G06T 2207/10101 (20130101)
G06T 2207/20021 (20130101)
G06T 2207/20024 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/20221 (20130101)
G06T 2207/30041 (20130101)
G06T 2211/404 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11264422 Harmon
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) LightSpin Technologies Inc. (Endicott, New York)
ASSIGNEE(S) LightSpin Technologies Inc. (Endicott, New York)
INVENTOR(S) Eric Harmon (Norfolk, Massachusetts)
ABSTRACT A position-sensitive photodetector device includes a grid of series-connected photodetectors that are electrically coupled to either a vertical photodetector array (VA photodetectors) or to a horizontal photodetector array (HA photodetectors). The VA and HA photodetectors are arranged in an alternating sequence along rows and/or columns throughout the grid. A horizontal-position readout line is electrically coupled to a termination of each vertical photodetector array, and a vertical-position readout line is electrically coupled to a termination of each horizontal photodetector array.
FILED Friday, August 30, 2019
APPL NO 16/557149
ART UNIT 2826 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/1446 (20130101)
H01L 27/14601 (20130101)
H01L 27/14643 (20130101) Original (OR) Class
H01L 31/107 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11265717 Traynor et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Patrick G. Traynor (Gainesville, Florida);  Christian Peeters (Gainesville, Florida);  Bradley G. Reaves (Raleigh, North Carolina);  Hadi Abdullah (Gainesville, Florida);  Kevin Butler (Gainesville, Florida);  Jasmine Bowers (Gainesville, Florida);  Walter N. Scaife (Gainesville, Florida)
ABSTRACT Disclosed are various embodiments for detecting Signaling System 7 (SS7) redirection attacks by measuring call audio round trip times between phones. Such redirection attacks force calls to travel longer physical distances than usual, thereby causing longer end-to-end delay. Accordingly, various embodiments implement a distance bounding-inspired protocol that allows for securely characterizing the round trip time between two call endpoints. As a result, telephone users can reliably detect SS7 redirection attacks and protect the information contained in their calls.
FILED Tuesday, March 19, 2019
APPL NO 16/357998
ART UNIT 2496 — Optical Communications
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/3271 (20130101)

Telephonic Communication
H04M 3/2281 (20130101)

Wireless Communication Networks
H04W 12/50 (20210101)
H04W 12/121 (20210101) Original (OR) Class
H04W 12/0433 (20210101)
H04W 64/006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11259580 Young et al.
FUNDED BY
Department of Defense (DOD)
Defense Health Agency (DHA)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Cornerstone Research Group, Inc. (Miamisburg, Ohio)
ASSIGNEE(S) Cornerstone Research Group, Inc. (Miamisburg, Ohio)
INVENTOR(S) Trang T. Young (Dayton, Ohio);  Mark C. Cridge (Miamisburg, Ohio);  Scott A. Miller (Dayton, Ohio);  Joshua E. Nieman (Centerville, Ohio);  Gary N. Cupp (Washington Township, Ohio);  Kristin M. Cable (Dayton, Ohio)
ABSTRACT A health monitoring garment is provided. The health monitoring garment includes an article of clothing comprising at least one compression section to provide a snug fit against a person wearing the article of clothing and a sensor island. The sensor island includes stretchable circuitry, two or more sensors, one or more power supplies, and optionally one or more wireless communication modules within a self-contained unit. At least one of the sensors comprises a stretchable sensor which may be a respiration sensor. The sensor unit may be provided independent of the health monitoring garment or as a complete system. The sensor island and compression section of the article of clothing also include fasteners of complementary geometries for reversible attachment and disengagement of the sensor island from the compression section.
FILED Tuesday, July 23, 2019
APPL NO 16/519511
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Outerwear; Protective Garments; Accessories
A41D 13/1281 (20130101) Original (OR) Class

Diagnosis; Surgery; Identification
A61B 5/01 (20130101)
A61B 5/0002 (20130101)
A61B 5/08 (20130101)
A61B 5/0053 (20130101)
A61B 5/02055 (20130101)
A61B 5/02438 (20130101)
A61B 5/6804 (20130101)
A61B 5/14517 (20130101)
A61B 2560/0214 (20130101)
A61B 2562/06 (20130101)
A61B 2562/0219 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11259717 Thompson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
U.S. Air Force
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Kyle Thompson (Lynnfield, Massachusetts);  Gary A Shaw (Westford, Massachusetts);  Andrew M Siegel (Arlington, Massachusetts);  Lawrence M Candell (Arlington, Massachusetts)
ABSTRACT A fluid dynamic valve passively allows fluid flow out of a moving stream in one flow direction and not in the reverse. This allows the collection of fluid from a single direction of an AC fluid flow. The siphoned portion of the flow has a flow rate proportional to the mainstream flow. This device can collect exhaled breath or selective entrenchment during inhale. In one orientation, it can meter aerosolized particles into an inhale breath stream for pulmonary delivery, without complicated breath timing or drug loss due to drug adsorption to the back of the throat. Alternatively, a user can breathe through the device and a proportional amount, relative to the volumetric flow rate, of each exhale can flow into an auxiliary chamber for analysis. In addition, the device has a low respiratory burden and is comfortable to use.
FILED Thursday, May 16, 2019
APPL NO 16/413980
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/082 (20130101)
A61B 5/083 (20130101)
A61B 5/087 (20130101)
A61B 5/097 (20130101) Original (OR) Class
A61B 5/0833 (20130101)
A61B 5/0836 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 2230/432 (20130101)
A61M 2230/435 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260133 Ruoslahti et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Erkki Ruoslahti (Buellton, California);  Tambet Teesalu (Goleta, California);  Kazuki Sugahara (Goleta, California)
ASSIGNEE(S) SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (La Jolla, California)
INVENTOR(S) Erkki Ruoslahti (Buellton, California);  Tambet Teesalu (Goleta, California);  Kazuki Sugahara (Goleta, California)
ABSTRACT Disclosed are compositions and methods useful for targeting and internalizing molecules into cells of interest and for penetration by molecules of tissues of interest. The compositions and methods are based on peptide sequences that are selectively internalized by a cell, penetrate tissue, or both. The disclosed internalization and tissue penetration is useful for delivering therapeutic and detectable agents to cells and tissues of interest.
FILED Friday, February 20, 2009
APPL NO 12/390061
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/62 (20170801)
A61K 47/64 (20170801)
A61K 47/6923 (20170801) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260468 Frank et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) UNIVERSITY OF NORTH TEXAS (Dallas, Texas)
ASSIGNEE(S) University of North Texas (Dallas, Texas)
INVENTOR(S) Michael Frank (Dallas, Texas);  Tianhao Wang (Dallas, Texas);  Rajiv Mishra (Dallas, Texas)
ABSTRACT A friction stir welding tool comprises a cylindrical shank, a shoulder portion disposed at a distal end of the shank, a pin extending from the shoulder, a cutting insert mounted within a concave portion at the distal end of the shank, and a scribe cutter mounted at a distal end of the cutting insert. The cutting insert extends distally through a channel in the pine, and the scribe cutter extends from a distal end surface of the pin in an offset position. The distal end surface of the pin is perpendicular to a longitudinal axis of the shank.
FILED Friday, July 10, 2020
APPL NO 16/926194
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 20/00 (20130101)
B23K 20/125 (20130101)
B23K 20/1255 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260586 Fink et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Yoel Fink (Brookline, Massachusetts);  Gabriel Zi Jie Loke (Cambridge, Massachusetts);  Rodger Yuan (Boston, Massachusetts)
ABSTRACT In a method for printing a three dimensional structure, a continuous length of fiber that includes, interior to a surface of the fiber, a plurality of different materials arranged as an in-fiber functional domain, with at least two electrical conductors disposed in the functional domain in electrical contact with at least one functional domain material, is dispensed through a single heated nozzle. After sections of the length of fiber are dispensed from the heated nozzle, the sections are fused together in an arrangement of a three dimensional structure. The structure can thereby include a continuous length of fiber of least three different materials arranged as an in-fiber functional device, with the continuous length of fiber disposed as a plurality of fiber sections that are each in a state of material fusion with another fiber section in a spatial arrangement of the structure.
FILED Friday, November 17, 2017
APPL NO 15/816964
ART UNIT 1786 — Miscellaneous Articles, Stock Material
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/118 (20170801)
B29C 64/209 (20170801) Original (OR) Class
B29C 70/88 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2101/12 (20130101)
B29K 2827/18 (20130101)
B29K 2905/12 (20130101)
B29K 2995/0005 (20130101)
B29K 2995/0013 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/34 (20130101)
B29L 2031/3468 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 80/00 (20141201)

Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 7/16 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 7/0233 (20130101)
H01B 7/0275 (20130101)
H01B 13/14 (20130101)
H01B 13/0016 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/032 (20130101)
H01L 31/0203 (20130101)
H01L 41/23 (20130101)
H01L 41/0533 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/386 (20130101)
H01M 4/387 (20130101)
H01M 4/505 (20130101)
H01M 4/525 (20130101)
H01M 4/587 (20130101)
H01M 4/5825 (20130101)
H01M 10/058 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 33/04 (20130101)
H05B 33/10 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 5/065 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261187 Haystead et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Timothy A. J. Haystead (Chapel Hill, North Carolina);  Philip Floyd Hughes (Chapel Hill, North Carolina)
ABSTRACT Described herein are compounds that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. The compounds may allow for selective detection of Hsp90 in a sample.
FILED Friday, April 21, 2017
APPL NO 16/095411
ART UNIT 1699 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 403/14 (20130101)
C07D 487/04 (20130101) Original (OR) Class
C07D 491/107 (20130101)
C07D 498/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261253 Zang
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York)
ASSIGNEE(S) Albert Einstein College of Medicine (Bronx, New York)
INVENTOR(S) Xingxing Zang (New York, New York)
ABSTRACT Provided are methods of treating an autoimmune disease in a subject, or of suppressing transplant rejection in a subject, or of treating a cancer in a subject, as well as compositions therefor.
FILED Wednesday, September 05, 2018
APPL NO 16/121771
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 16/2827 (20130101) Original (OR) Class
C07K 2317/21 (20130101)
C07K 2317/24 (20130101)
C07K 2319/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261821 Meininger et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Redstone Arsenal (REDSTONE)
APPLICANT(S) Science Applications International Corporation (Reston, Virginia);  Government of the United States, as Represented by the Secretary of the Army (Redstone Arsenal, Alabama)
ASSIGNEE(S) Science Application International Corporation (Reston, Virginia);  U.S. Government as Represented by the Secretary of the Army (Redstone Arsenal, Alabama)
INVENTOR(S) Rik Denis Meininger (Huntsville, Alabama);  Bernard Acker (Madison, Alabama)
ABSTRACT An aircraft diesel engine may be operated at a minimal fuel rate. Shaft output power of the engine may be reduced by initiating combustion during the compression stroke. Combustion may be initiated during the compression stroke by advancing fuel injection, splitting fuel injection, and/or manipulating individual injection quantities. Initiating combustion during the compression stroke may slew torque generation to the compression stroke.
FILED Wednesday, September 23, 2020
APPL NO 17/029505
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 27/08 (20130101)

Controlling Combustion Engines
F02D 35/00 (20130101)
F02D 41/08 (20130101)
F02D 41/402 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261891 Leutwyler et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) KALSI ENGINEERING, INC. (Sugar Land, Texas)
ASSIGNEE(S) KALSI ENGINEERING, INC. (Sugar Land, Texas)
INVENTOR(S) Zachary W Leutwyler (Richmond, Texas);  Manmohan S Kalsi (Houston, Texas)
ABSTRACT A flow conditioning assembly comprising an integral elbow flow conditioner and a downstream flow conditioner. The elbow flow conditioner includes a pipe elbow with one or more flow conditioning elements. Each flow conditioning element includes one or more turning guides. Each turning guide is generally circular and radially spaced from one another and an inner surface of the elbow. Spaced vanes maintain the radial spacing of the turning guides. The vanes divide the radial space between the turning guides and pipe elbow into a plurality of flow channels that turn in generally the same direction as the inner surface of the pipe elbow. The downstream flow conditioner comprises a flow conditioning structure within a pipe element. The flow conditioning structure includes one or more flow guides of generally circular form radially spaced from one another and the pipe element. Spaced support vanes maintain the radial spacing of the flow guides.
FILED Wednesday, May 12, 2021
APPL NO 17/318851
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids
F15D 1/04 (20130101) Original (OR) Class
F15D 1/06 (20130101)
F15D 1/0025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261902 Adams
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Sea Systems Command (NAVSEA)
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Richard J. Adams (Charlestown, Massachusetts)
ABSTRACT A pin lock fastener comprises a fastener component (e.g., bolt or nut) having an aperture formed through an outer surface of the fastener component, and a pin supported by the fastener component and slidable through the aperture. The pin can comprise a locking end portion to interface/lock with a pin lock feature of a fastener receiver structure. The pin lock fastener can comprise an actuator cap rotatably coupled to the fastener component, and a torsion spring can have a first end coupled to the fastener component and a second end coupled to the actuator cap. The pin can be secured to the torsion spring that applies a biasing force to the pin in a normal locked position to restrict rotation of the fastener component relative to the fastener receiver structure secured to the fastener component. The pin lock fastener can be repeatedly used. Associated fastened assemblies and methods are provided.
FILED Wednesday, June 12, 2019
APPL NO 16/439562
ART UNIT 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing
F16B 37/14 (20130101)
F16B 39/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261910 Boss et al.
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Jakob M. Boss (Tucson, Arizona);  Michael B. Smith (Tucson, Arizona);  William A. Wilson (Tucson, Arizona);  Sellena M. Urias (Tucson, Arizona);  William Straus (Tucson, Arizona)
ABSTRACT A precision linear bearing is designed to minimize the points of contact, rolling and rubbing, to reduce particulates and FOD while ensuring stability and accuracy in a manner suitable for a clean room environment. The linear bearing comprises at least first and second bearing layers within a one-piece housing. Each bearing layer comprises at least three roller bearing spaced around the axial bore in a first plane within the housing, each roller bearing having an axis of rotation substantially perpendicular to the axial bore and projecting into said axial bore for engagement of a linear member extending through the axial bore. Each roller bearing suitably engages the linear member at a single point of contact. The layers are rotationally offset from one another such that the roller bearings contact different positions around the circumference of the linear member. The linear bearing may be configured to engage the inner surface of a cylindrical member.
FILED Tuesday, November 10, 2020
APPL NO 17/094312
ART UNIT 3656 — Material and Article Handling
CURRENT CPC
Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings
F16C 29/008 (20130101) Original (OR) Class
F16C 29/045 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262073 Duncan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) GENERAL ELECTRIC COMPANY (Schenectady, New York)
INVENTOR(S) Beverly Stephenson Duncan (West Chester, Ohio);  Eric John Stevens (Mason, Ohio);  Steven Joseph Lohmueller (Reading, Ohio)
ABSTRACT A trapped vortex combustor for use in a gas turbine engine includes an outer vortex chamber wall and a dome attached to, or formed integrally with, the outer vortex chamber wall. The dome, the outer vortex chamber wall, or both define at least in part an outer trapped vortex chamber and a channel. The channel extends along the circumferential direction at a forward end of the outer vortex chamber wall, the channel configured to receive an airflow through or around the outer vortex chamber wall, the dome, or both and provide such airflow as a continuous annular airflow to the inner surface of the outer vortex chamber wall. The dome further defines a fuel nozzle opening, with all openings in the dome outward of the fuel nozzle opening along the radial direction, excepting any effusion cooling holes having a diameter less than about 0.035 inches, being in airflow communication with the channel.
FILED Tuesday, May 02, 2017
APPL NO 15/584057
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers
F23R 3/002 (20130101)
F23R 3/06 (20130101) Original (OR) Class
F23R 3/12 (20130101)
F23R 3/30 (20130101)
F23R 3/50 (20130101)
F23R 3/58 (20130101)
F23R 3/286 (20130101)
F23R 2900/00015 (20130101)
F23R 2900/03041 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262172 Mannix
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Gregory S. Mannix (Oxford, Pennsylvania)
ABSTRACT An ammunition storage compartment includes a plurality of connected walls defining an interior region to store ammunition, wherein at least one of the walls includes an outer armor plate having an outer surface and an inner surface. A layer of energy absorbing material is located proximate the inner surface of the armor plate in the interior region. A spall mitigating panel is located inward of the layer of energy absorbing material in the interior region. At least one air gap is in between the layer of energy absorbing material and the spall mitigating panel.
FILED Tuesday, December 19, 2017
APPL NO 15/846244
ART UNIT 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General
F41H 5/04 (20130101)
F41H 5/023 (20130101)
F41H 5/0485 (20130101)

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 39/14 (20130101)
F42B 39/24 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262241 Furstenberg et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Robert Furstenberg (Burke, Virginia);  Chris Kendziora (Burke, Virginia);  R. Andrew McGill (Lorton, Virginia)
ABSTRACT A photo-thermal speckle spectroscopy device having an infrared laser, a visible laser, a foam, and a camera. The infrared and visible lasers are focused on the foam, which causes the visible laser to scatter. A camera records the speckle pattern, which shifts when the IR laser is turned on. The related method of photo-thermal speckle spectroscopy is also disclosed.
FILED Monday, August 03, 2020
APPL NO 16/983578
ART UNIT 2886 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/021 (20130101)
G01J 3/108 (20130101)
G01J 3/0205 (20130101)
G01J 3/0218 (20130101)
G01J 3/433 (20130101)
G01J 3/447 (20130101)
G01J 3/2823 (20130101) Original (OR) Class
G01J 3/4338 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/39 (20130101)
G01N 21/45 (20130101)
G01N 21/636 (20130101)
G01N 21/1717 (20130101)
G01N 21/4788 (20130101)
G01N 2021/399 (20130101)
G01N 2021/479 (20130101)
G01N 2021/1725 (20130101)

Optical Elements, Systems, or Apparatus
G02B 27/48 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262301 Hug et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Office (CCDC ARO)
National Aeronautics and Space Administration (NASA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Photon Systems, Inc. (Covina, California)
ASSIGNEE(S) Photon Systems, Inc. (Covina, California)
INVENTOR(S) William F. Hug (Altadena, California);  Rohit Bhartia (Pasadena, California);  Ray D. Reid (Glendora, California);  Arthur L. Lane (Arcadia, California)
ABSTRACT Naphthalene, benzene, toluene, xylene, and other volatile organic compounds VOCs have been identified as serious health hazards. Embodiments of the invention are directed to methods and apparatus for near-real-time in-situ detection and accumulated dose measurement of exposure to naphthalene vapor and other hazardous gaseous VOCs. The methods and apparatus employ excitation of fluorophors native or endogenous to compounds of interest using light sources emitting in the ultraviolet below 300 nm and measurement of native fluorescence emissions in distinct wavebands above the excitation wavelength. The apparatus of some embodiments are cell-phone-sized sensor/dosimeter “badges” to be worn by personnel potentially exposed to hazardous VOCs. The badge sensor of some embodiments provides both real time detection and data logging of exposure to naphthalene or other VOCs of interest from which both instantaneous and accumulated dose can be determined.
FILED Friday, September 04, 2020
APPL NO 17/013469
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/10 (20130101)
G01J 3/36 (20130101)
G01J 3/44 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/64 (20130101) Original (OR) Class
G01N 21/65 (20130101)
G01N 21/6486 (20130101)
G01N 21/8806 (20130101)
G01N 27/44721 (20130101)
G01N 33/0047 (20130101)
G01N 2021/6421 (20130101)
G01N 2021/6471 (20130101)
G01N 2201/062 (20130101)
G01N 2201/126 (20130101)
G01N 2201/0612 (20130101)
G01N 2201/06113 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262450 Obenberger et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Kirtland AFB, New Mexico)
ASSIGNEE(S) Government of the United States, as Represented by the Secretary of the Air Force (Kirtland AFB, New Mexico)
INVENTOR(S) Kenneth S. Obenberger (Albuquerque, New Mexico);  Richard T. Parris (Albuquerque, New Mexico);  Todd R. Pedersen (Albuquerque, New Mexico)
ABSTRACT A system, computer program product and method of examining the ionosphere is disclosed. The method includes capturing, at one or more antennas, radio frequency (RF) emissions preceding a broadband emission event. The RF emissions are then recorded at one or more broadband receivers over a period of time. A first tuning of the received RF emissions is selected to detect ionospheric reflections, and a second tuning of the received RF emissions is selected to detect direct line of sight emissions. From the selected tunings, an amplitude or complex time series of the second tuning with one or more channels of the first tuning are correlated to calculate a relative virtual echo height of the ionosphere.
FILED Thursday, September 27, 2018
APPL NO 16/144511
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 13/951 (20130101) Original (OR) Class
G01S 13/958 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262457 Zarowski et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
Naval Air Warfare Center (NAWC)
APPLICANT(S) Mayflower Communications Company, Inc. (Bedford, Massachusetts)
ASSIGNEE(S) Mayflower Communications Company, INC. (Bedford, Massachusetts)
INVENTOR(S) Christopher Jonathan Zarowski (Burlington, Massachusetts);  Huan-Wan Tseng (Westford, Massachusetts);  William LeComte (Burlington, Massachusetts)
ABSTRACT System and method for concurrently protecting Iridium and GPS L1/L2 band received satellite signals against interference signals (e.g., jamming signals) using space-time adaptive processing (STAP). While the GPS signal is protected against jamming using Nulling of the interfering signals, the Iridium signal is protected using Beamforming. A single broadband small controlled reception pattern antenna (sCRPA) array receives both the GPS (L1 and L2) and Iridium signals for the STAP-based antijam solutions outputting filtered Iridium and GPS signals. Use of a common (small) broadband antenna and common front end signal processing of the received signals enables an integrated system for use on size, weight, and power constrained platforms such as drones, unmanned aerial vehicles (UAVs), and helicopters.
FILED Tuesday, January 29, 2019
APPL NO 16/260468
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 19/14 (20130101)
G01S 19/21 (20130101) Original (OR) Class
G01S 19/23 (20130101)
G01S 19/36 (20130101)
G01S 19/215 (20130101)
G01S 19/246 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262785 Monroe et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Security Agency (NSA)
Maryland Procurement Office (MPO)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland)
INVENTOR(S) Christopher Monroe (Ellicott City, Maryland);  Jiehang Zhang (College Park, Maryland);  David Wong-Campos (Hyattsville, Maryland);  Antonios Kyprianidis (Takoma, Maryland);  Patrick Michael Becker (College Park, Maryland)
ABSTRACT The disclosure describes an adaptive and optimal imaging of individual quantum emitters within a lattice or optical field of view for quantum computing. Advanced image processing techniques are described to identify individual optically active quantum bits (qubits) with an imager. Images of individual and optically-resolved quantum emitters fluorescing as a lattice are decomposed and recognized based on fluorescence. Expected spatial distributions of the quantum emitters guides the processing, which uses adaptive fitting of peak distribution functions to determine the number of quantum emitters in real time. These techniques can be used for the loading process, where atoms or ions enter the trap one-by-one, for the identification of solid-state emitters, and for internal state-detection of the quantum emitters, where each emitter can be fluorescent or dark depending on its internal state. This latter application is relevant to efficient and fast detection of optically active qubits in quantum simulations and quantum computing.
FILED Thursday, January 03, 2019
APPL NO 16/239084
ART UNIT 2878 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)
B82Y 40/00 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 1/42 (20130101)
G01J 2001/4247 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6458 (20130101)

Optical Computing Devices;
G06E 3/005 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/66977 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11263011 Cassidy et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Air Force Research Laboratory (AFRL)
U.S. Air Force
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Andrew S. Cassidy (San Jose, California);  Rathinakumar Appuswamy (San Jose, California);  John V. Arthur (Mountain View, California);  Pallab Datta (San Jose, California);  Michael V. Debole (Poughkeepsie, New York);  Steven K. Esser (San Jose, California);  Myron D. Flickner (San Jose, California);  Dharmendra S. Modha (San Jose, California);  Hartmut Penner (San Jose, California);  Jun Sawada (Austin, Texas);  Brian Taba (Cupertino, California)
ABSTRACT A device for controlling neural inference processor cores is provided, including a compound instruction set architecture. The device comprises an instruction memory, which comprises a plurality of instructions for controlling a neural inference processor core. Each of the plurality of instructions comprises a control operation. The device further comprises a program counter. The device further comprises at least one loop counter register. The device is adapted to execute the plurality of instructions. Executing the plurality of instructions comprises: reading an instruction from the instruction memory based on a value of the program counter; updating the at least one loop counter register according to the control operation of the instruction; and updating the program counter according to the control operation of the instruction and a value of the at least one loop counter register.
FILED Wednesday, November 28, 2018
APPL NO 16/202871
ART UNIT 2183 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 9/324 (20130101)
G06F 9/3013 (20130101) Original (OR) Class
G06F 9/30065 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11263250 Mugan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) PULSELIGHT HOLDINGS, INC. (Austin, Texas)
ASSIGNEE(S) Pulselight Holdings, Inc. (Austin, Texas)
INVENTOR(S) Jonathan William Mugan (Buda, Texas);  Laura Hitt (Austin, Texas);  Jimmie Goode (Austin, Texas);  Russ Gregory (Austin, Texas);  Yuan Qu (Austin, Texas)
ABSTRACT A recurrent neural network (RNN) method implemented on a computer system is used to produce summaries of unstructured text generated by multiple networks of individuals interacting over time by encoding the unstructured text into intermediate representations and decoding the intermediate representations into summaries of each network. Parameter data for the RNN is obtained by using multiple different versions of the same source texts to train the computer system. The method and computer system can be used to identify which of the networks match a query by determining which network generates the query with low or lowest cost.
FILED Monday, October 14, 2019
APPL NO 16/601428
ART UNIT 2657 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC
Electric Digital Data Processing
G06F 16/334 (20190101)
G06F 16/345 (20190101) Original (OR) Class
G06F 40/30 (20200101)
G06F 40/58 (20200101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11263339 Denker et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) SRI International (Menlo Park, California)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Grit Denker (Palo Alto, California);  Karsten Martiny (Milbrae, California);  Daniel Elenius (Redwood City, California)
ABSTRACT In general, techniques for data access control are described, in which a policy engine implements and applies a declarative policy framework that can represent and reason about complex privacy policies. By using a common data model together with a formal shareability theory, this declarative policy framework enables the specification of expressive policies in a concise way without burdening the user with technical details of the underlying formalism of a data querying application or other knowledge representation scheme. The policy engine may be deployed as the policy decision point in a data access control system that also includes a policy enforcement point. The policy engine includes user interfaces for the creation, validation, and management of privacy policies. The policy engine may interface with systems that manage data requests and replies by coordinating policy engine decisions and access to databases.
FILED Wednesday, September 04, 2019
APPL NO 16/560930
ART UNIT 2166 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 21/6227 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11263522 Nestler et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) Analog Devices, Inc. (Norwood, Massachusetts)
ASSIGNEE(S) Analog Devices, Inc. (Norwood, Massachusetts)
INVENTOR(S) Eric G. Nestler (Long Beach Township, New Jersey);  Naveen Verma (Princeton, New Jersey);  Hossein Valavi (Princeton, New Jersey)
ABSTRACT Systems and methods are provided for reducing power in in-memory computing, matrix-vector computations, and neural networks. An apparatus for in-memory computing using charge-domain circuit operation includes transistors configured as memory bit cells, transistors configured to perform in-memory computing using the memory bit cells, capacitors configured to store a result of in-memory computing from the memory bit cells, and switches, wherein, based on a setting of each of the switches, the charges on at least a portion of the plurality of capacitors are shorted together. Shorting together the plurality of capacitors yields a computation result.
FILED Friday, September 07, 2018
APPL NO 16/125621
ART UNIT 2123 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/061 (20130101)
G06N 3/0454 (20130101)
G06N 3/0481 (20130101)
G06N 3/0635 (20130101) Original (OR) Class

Static Stores
G11C 11/54 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11263546 Heeres et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Reinier Heeres (Heemskerk, Netherlands);  Philip Reinhold (New Haven, Connecticut);  Victor V. Albert (New Haven, Connecticut);  Liang Jiang (Guilford, Connecticut);  Luigi Frunzio (North Haven, Connecticut);  Michel Devoret (New Haven, Connecticut);  Robert J. Schoelkopf, III (Madison, Connecticut)
ABSTRACT Techniques are described in which a qubit is far off-resonantly, or dispersively, coupled to a quantum mechanical oscillator. In particular, a dispersive coupling between a physical qubit and a quantum mechanical oscillator may be selected such that control of the combined qubit-oscillator system can be realized. The physical qubit may be driven with an electromagnetic pulse (e.g., a microwave pulse) and the quantum mechanical oscillator simultaneously driven with another electromagnetic pulse, the combination of which results in a change in state of the qubit-oscillator system.
FILED Friday, July 22, 2016
APPL NO 15/747260
ART UNIT 2125 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 9/30101 (20130101)

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11264134 Temkin et al.
FUNDED BY
Department of Defense (DOD)
Defense Health Agency (DHA)
Department of the Army (DOA)
APPLICANT(S) Pleiotek (Bethesda, Maryland)
ASSIGNEE(S) Pleiotek (Bethesda, Maryland)
INVENTOR(S) Joshua Michael Temkin (Bethesda, Maryland);  Melissa Greenfield Temkin (Bethesda, Maryland)
ABSTRACT A wearable data storage and transmission device and related systems that collect and store sensor data from sensors worn by a user. The device components can include a processor, battery, data storage media, NFC components, Bluetooth components, Wi-Fi components, and wired communications components. The device can remain powered down, powering up periodically to collect sensor data using low energy methods and/or in response to receiving a signal (e.g., NFC, power, Bluetooth, etc.) from an external device that causes the device to power up its components and make sensor data available to the external device. The collected sensor data may be encoded, compressed, stored, and/or exchanged in one or more structured records using various methods to improve the information storage capabilities of the device, including using the disclosed QR coding methods.
FILED Tuesday, May 11, 2021
APPL NO 17/316786
ART UNIT 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Electric Digital Data Processing
G06F 1/163 (20130101)
G06F 1/1656 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 10/60 (20180101)
G16H 40/67 (20180101) Original (OR) Class

Transmission
H04B 5/0031 (20130101)
H04B 5/0037 (20130101)

Wireless Communication Networks
H04W 4/027 (20130101)
H04W 4/38 (20180201)
H04W 4/80 (20180201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11264144 Houten et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Spark Thermionics, Inc. (Berkeley, California)
ASSIGNEE(S) Spark Thermionics, Inc. (Emeryville, California)
INVENTOR(S) Kyana Van Houten (Berkeley, California);  Lucas Heinrich Hess (Berkeley, California);  Jared William Schwede (Berkeley, California);  Felix Schmitt (Berkeley, California)
ABSTRACT A thermionic energy conversion system, preferably including one or more electron collectors, interfacial layers, encapsulation, and/or electron emitters. A method for manufacturing the thermionic energy conversion system. A method of operation for a thermionic energy conversion system, preferably including receiving power, emitting electrons, and receiving the emitted electrons, and optionally including convectively transferring heat.
FILED Thursday, May 06, 2021
APPL NO 17/313945
ART UNIT 2894 — Semiconductors/Memory
CURRENT CPC
Obtaining Energy From Radioactive Sources; Applications of Radiation From Radioactive Sources, Not Otherwise Provided For; Utilising Cosmic Radiation
G21H 1/106 (20130101) Original (OR) Class

Electric Discharge Tubes or Discharge Lamps
H01J 45/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11264422 Harmon
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) LightSpin Technologies Inc. (Endicott, New York)
ASSIGNEE(S) LightSpin Technologies Inc. (Endicott, New York)
INVENTOR(S) Eric Harmon (Norfolk, Massachusetts)
ABSTRACT A position-sensitive photodetector device includes a grid of series-connected photodetectors that are electrically coupled to either a vertical photodetector array (VA photodetectors) or to a horizontal photodetector array (HA photodetectors). The VA and HA photodetectors are arranged in an alternating sequence along rows and/or columns throughout the grid. A horizontal-position readout line is electrically coupled to a termination of each vertical photodetector array, and a vertical-position readout line is electrically coupled to a termination of each horizontal photodetector array.
FILED Friday, August 30, 2019
APPL NO 16/557149
ART UNIT 2826 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/1446 (20130101)
H01L 27/14601 (20130101)
H01L 27/14643 (20130101) Original (OR) Class
H01L 31/107 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11264702 Chieh et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Information Warfare Center (NIWC)
Naval Information Warfare Center Pacific (NIWCPACIFIC)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (San Diego, California)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jia-Chi Samuel Chieh (San Diego, California);  Everly S. Yeo (San Diego, California);  Randall B. Olsen (Carlsbad, California)
ABSTRACT A wideband antenna transmits and/or receives electromagnetic radiation. The wideband antenna includes a feedline, a first dielectric layer, a via, a driven patch, a second dielectric layer, and a parasitic patch. The feedline couples a radiofrequency signal and an element of the wideband antenna. The first dielectric layer is between the feedline and the driven patch. The via couples the radiofrequency signal of the feedline through the first dielectric layer. The driven patch couples between the electromagnetic radiation and the radiofrequency signal of the via. The second dielectric layer has a low dielectric constant of less than 1.3. The parasitic patch is electrically isolated from the driven patch by the second dielectric layer between the driven patch and the parasitic patch. The parasitic patch electromagnetically couples with the driven patch and the electromagnetic radiation to produce a wideband frequency response of the wideband antenna.
FILED Wednesday, October 14, 2020
APPL NO 17/070550
ART UNIT 2644 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/523 (20130101)
H01Q 1/2283 (20130101) Original (OR) Class
H01Q 3/36 (20130101)
H01Q 9/0414 (20130101)

Transmission
H04B 1/44 (20130101)
H04B 1/401 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11264980 Darwish
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) U.S. Army Combat Capabilities Development Command, Army Research Laboratory (Adelphi, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Ali Darwish (Highland, Maryland)
ABSTRACT Time folding power combining circuits convert a continuous wave into a pulsed wave of greater peak power. Such a circuit may comprise: a switch which receives a continuous wave signal as input, and outputs first and second pulsed wave signals along first and second signal paths, respectively, said switch being configured to repeatedly switch connection back and forth between the input and the outputs of the first and second signal paths in a plurality of time frames; a delay line in the second signal path configured to introduce a time delay to the second pulsed wave signal in the second signal path such that the first pulsed wave signal in the first signal path and the time-delayed second pulsed wave signal in the second signal path substantially align in the same time frames; and a combiner, which receives the first pulsed wave signal in the first signal path and the time-delayed pulsed second wave signal in the second signal path as inputs, and combines them into a single combined pulsed wave signal as output.
FILED Tuesday, March 02, 2021
APPL NO 17/189864
ART UNIT 2849 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 7/537 (20130101)

Pulse Technique
H03K 5/06 (20130101)
H03K 5/26 (20130101)
H03K 12/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11264991 Lukefahr et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Trustees of Indiana University (Indianapolis, Indiana);  The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S)
INVENTOR(S) Andrew Lukefahr (Bloomington, Indiana);  Adam Duncan (Bloomington, Indiana)
ABSTRACT A field-programmable gate array (FPGA) architecture capable of performing immutable hardware Root-of-Trust updates and patches. In embodiments, the architecture utilizes the dielectric breakdown mechanism of magneto tunnel junctions (MTJ) to operate both as: 1) multi-time programmable (MTP) configuration memory for reconfigurable FPGA designs, and 2) one-time programmable (OTP) memory for FPGA Root-of-Trust sections.
FILED Wednesday, November 25, 2020
APPL NO 17/104648
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Pulse Technique
H03K 19/1776 (20130101) Original (OR) Class
H03K 19/17708 (20130101)
H03K 19/17728 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11265040 Martone et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) CCDC Army Research Laboratory (Adelphi, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Anthony F. Martone (Ellicott City, Maryland);  Kyle A. Gallagher (Silver Spring, Maryland);  Kelly D. Sherbondy (Burke, Virginia)
ABSTRACT A method and system for providing a cooperative spectrum sharing model that jointly optimizes primary user equipment parameters for improved frequency agility and performance while mitigating mutual interference between the primary user equipment and secondary user equipment. Spectrum sensing is implemented to form a power spectral estimate of the electromagnetic environment (EME) and apply multi-objective optimization to adjust the operational parameters of the primary user equipment to mitigate interference.
FILED Wednesday, October 30, 2019
APPL NO 16/668627
ART UNIT 2642 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/4008 (20130101)
G01S 7/4013 (20210501)

Computer Systems Based on Specific Computational Models
G06N 3/126 (20130101)

Transmission
H04B 1/7113 (20130101) Original (OR) Class

Wireless Communication Networks
H04W 16/14 (20130101)
H04W 52/242 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11265151 Cambou et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Arizona Board of Regents on Behalf of Northern Arizona University (Flagstaff, Arizona);  Government of the United States of America, as represented by the Secretary of the Air Force (Rome, New York)
ASSIGNEE(S) Arizona Board of Regents on Behalf of Northern Arizona University (Flagstaff, Arizona);  Government of the United States of America, as represented by the Secretary of the Air Force (Rome, New York)
INVENTOR(S) Bertrand F Cambou (Flagstaff, Arizona);  Christopher Robert Philabaum (Flagstaff, Arizona);  Donald A. Telesca, Jr. (Whitesboro, New York)
ABSTRACT A computing device includes an array of addressable elements. Each addressable element is a hardware element that generates a substantially consistent response when interrogated. The device includes a processor coupled to the array of addressable elements and configured to communicate using a communication network. The processor receives a public key, and processes the public key to produce at least a set of addresses. Each address in the set of addresses identifies one or more hardware elements in the array of addressable elements. The processor generates a set of responses by interrogating the one or more hardware elements in the array of addressable elements identified by the set of addresses according to a set of reading instructions, appends the responses in the set of responses to generate a private key, receives an encrypted message and decrypts the encrypted message using the private key to generate an unencrypted message.
FILED Friday, March 08, 2019
APPL NO 16/297438
ART UNIT 2492 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/30 (20130101)
H04L 9/0819 (20130101) Original (OR) Class
H04L 9/3242 (20130101)
H04L 9/3278 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11265627 Proietti et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Roberto Proietti (Davis, California);  Sung-Joo Ben Yoo (Davis, California)
ABSTRACT The disclosed system implements a bandwidth-reconfigurable optical interconnect, which couples optical signals between N interconnect inputs and N interconnect outputs. The system includes an arrayed waveguide grating router (AWGR), which provides cyclic, single-wavelength, all-to-all routing between N AWGR inputs and N AWGR outputs. The system also includes a wavelength-insensitive switch, which provides all-wavelength, all-to-all connectivity between N wavelength-insensitive inputs and N wavelength-insensitive outputs. The system additionally includes a wavelength-selective input switch, which selectively directs up to L wavelengths from each of the N interconnect inputs into a corresponding input of the wavelength-insensitive switch, wherein unselected wavelengths from each of the N interconnect inputs pass into a corresponding AWGR input. Finally, the system includes a wavelength-selective output switch, which selectively directs up to L wavelengths from each of the N wavelength-insensitive outputs into a corresponding interconnect output, wherein each of the N AWGR outputs pass into a corresponding interconnect output.
FILED Wednesday, September 25, 2019
APPL NO 16/582902
ART UNIT 2637 — Optical Communications
CURRENT CPC
Multiplex Communication
H04J 14/0212 (20130101)

Selecting
H04Q 11/0005 (20130101) Original (OR) Class
H04Q 11/0066 (20130101)
H04Q 2011/0032 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11259703 Ghosh et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Kunal Ghosh (San Francisco, California);  Laurie D. Burns (Menlo Park, California);  Abbas El Gamal (Palo Alto, California);  Mark J. Schnitzer (Palo Alto, California);  Eric Cocker (Palo Alto, California);  Tatt Wei Ho (Stanford, California)
ABSTRACT Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mm2 and to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 μm resolution for an image of the field of view.
FILED Monday, October 26, 2020
APPL NO 17/080295
ART UNIT 2488 — Recording and Compression
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0042 (20130101)
A61B 5/0071 (20130101) Original (OR) Class
A61B 5/0082 (20130101)
A61B 5/489 (20130101)
A61B 90/20 (20160201)
A61B 2090/306 (20160201)
A61B 2503/40 (20130101)
A61B 2503/42 (20130101)
A61B 2562/04 (20130101)
A61B 2562/0233 (20130101)
A61B 2576/026 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6458 (20130101)

Optical Elements, Systems, or Apparatus
G02B 3/0087 (20130101)
G02B 21/0008 (20130101)
G02B 21/008 (20130101)
G02B 21/16 (20130101)
G02B 21/36 (20130101)
G02B 21/361 (20130101)
G02B 21/362 (20130101)
G02B 21/365 (20130101)
G02B 27/141 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 2207/30016 (20130101)
G06T 2207/30101 (20130101)

Pictorial Communication, e.g Television
H04N 5/2254 (20130101)
H04N 5/2256 (20130101)
H04N 5/23296 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260343 Worsley et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Marcus Worsley (Hayward, California);  Patrick Campbell (Oakland, California);  Sangil Kim (Chicago, Illinois);  Matthew Merrill (Dublin, California)
ABSTRACT In one embodiment, a method for separating acidic gases from a gas mixture includes exposing the gas mixture to a separation membrane at an elevated temperature, where the separation membrane includes a porous support and at least one molten alkali metal hydroxide disposed within pores of the porous support.
FILED Thursday, October 03, 2019
APPL NO 16/592532
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/40 (20130101)
B01D 53/62 (20130101)
B01D 53/82 (20130101)
B01D 53/228 (20130101) Original (OR) Class
B01D 53/508 (20130101)
B01D 53/565 (20130101)
B01D 61/38 (20130101)
B01D 69/02 (20130101)
B01D 69/10 (20130101)
B01D 69/12 (20130101)
B01D 71/02 (20130101)
B01D 71/022 (20130101)
B01D 71/024 (20130101)
B01D 2053/221 (20130101)
B01D 2251/306 (20130101)
B01D 2251/604 (20130101)
B01D 2257/50 (20130101)
B01D 2257/302 (20130101)
B01D 2257/404 (20130101)
B01D 2257/504 (20130101)
B01D 2258/0283 (20130101)
B01D 2311/13 (20130101)
B01D 2325/02 (20130101)
B01D 2325/04 (20130101)
B01D 2325/26 (20130101)

Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG]
Y02C 20/40 (20200801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260344 Worsley et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Marcus Worsley (Hayward, California);  Patrick Campbell (Oakland, California);  Sangil Kim (Chicago, Illinois);  Matthew Merrill (Dublin, California)
ABSTRACT In one embodiment, a separation membrane includes: a porous support structure, wherein the porous support structure comprises a system of continuous pores connecting an inlet of the separation membrane to an outlet of the separation membrane; and at least one alkali metal hydroxide disposed within pores of the porous support structure. Other aspects and embodiments of the disclosed inventive concepts will become apparent from the detailed description, which, when taken in conjunction with the drawings, illustrate by way of example the principles of the invention.
FILED Thursday, October 03, 2019
APPL NO 16/592579
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/40 (20130101)
B01D 53/62 (20130101)
B01D 53/82 (20130101)
B01D 53/228 (20130101) Original (OR) Class
B01D 53/508 (20130101)
B01D 53/565 (20130101)
B01D 61/38 (20130101)
B01D 69/02 (20130101)
B01D 69/10 (20130101)
B01D 69/12 (20130101)
B01D 71/02 (20130101)
B01D 71/022 (20130101)
B01D 71/024 (20130101)
B01D 2053/221 (20130101)
B01D 2251/306 (20130101)
B01D 2251/604 (20130101)
B01D 2257/50 (20130101)
B01D 2257/302 (20130101)
B01D 2257/404 (20130101)
B01D 2257/504 (20130101)
B01D 2258/0283 (20130101)
B01D 2311/13 (20130101)
B01D 2325/02 (20130101)
B01D 2325/04 (20130101)
B01D 2325/26 (20130101)

Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG]
Y02C 20/40 (20200801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260426 Kumar et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Sortera Alloys, Inc. (Fort Worth, Texas)
ASSIGNEE(S) Sortera Alloys, hic. (Fort Worth, Texas)
INVENTOR(S) Nalin Kumar (Fort Worth, Texas);  Manuel Gerardo Garcia, Jr. (Lexington, Kentucky);  Ronnie Kip Lowe (Westworth Village, Texas)
ABSTRACT A system classifies materials utilizing a vision system that implements a machine learning system, such as a neural network, in order to identify or classify each of the materials as either a monetary coin or not a monetary coin, which may then be sorted into separate groups based on such an identification or classification. Such a system can sort monetary coins from other forms of scrap, which may have been produced from a shredding of end of life vehicles.
FILED Sunday, April 19, 2020
APPL NO 16/852514
ART UNIT 3653 — Printing/Measuring and Testing
CURRENT CPC
Separating Solids From Solids by Sieving, Screening, Sifting or by Using Gas Currents; Separating by Other Dry Methods Applicable to Bulk Material, e.g Loose Articles Fit to be Handled Like Bulk Material
B07B 13/003 (20130101) Original (OR) Class
B07B 13/18 (20130101)

Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 5/342 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/48 (20130101)
G06K 9/627 (20130101)
G06K 2209/19 (20130101)

Image Data Processing or Generation, in General
G06T 7/0006 (20130101)
G06T 2207/30136 (20130101)
G06T 2207/30141 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261111 Wilson et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Aaron D. Wilson (Idaho Falls, Idaho);  Daniel S. Wendt (Idaho Falls, Idaho);  Christopher J. Orme (Firth, Idaho);  Birendra Adhikari (Ammon, Idaho);  Daniel M. Ginosar (Idaho Falls, Idaho)
ABSTRACT A method of treating an aqueous solution comprises forming a treatment stream comprising a condensable material. The treatment stream is introduced to an aqueous solution comprising water and a solute to fractionally precipitate the solute out of the aqueous solution and form a solids stream comprising the solute and an aqueous liquid stream comprising at least one solute-depleted solution of the water and the condensable material. The condensable material of at least a portion of the aqueous liquid stream is separated from the water of the at least a portion of the aqueous liquid stream to at least partially reform the treatment stream and form an aqueous liquid product stream depleted in the solute. Aqueous solution treatment systems and additional methods of treating an aqueous solution are also described.
FILED Friday, March 29, 2019
APPL NO 17/040271
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/20 (20130101)
C02F 1/5272 (20130101) Original (OR) Class
C02F 2103/18 (20130101)
C02F 2303/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261391 Dec et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) John E. Dec (Livermore, California);  Yi Yang (Box Hill North, Australia)
ABSTRACT A fuel or fuel blending agent for an internal combustion engine includes a ketone compound that is a C4 to C10 branched acyclic ketone, cyclopentanone, or a derivative of cyclopentanone. The ketone compound may be blended with a majority portion of a fuel selected from the group consisting of: gasoline, diesel, alcohol fuel, biofuel, renewable fuel, Fischer-Tropsch fuel, or combinations thereof. The ketone compound may be derived from biological sources. A method for powering an internal combustion engine with a fuel comprising the ketone compound is also provided.
FILED Wednesday, April 15, 2015
APPL NO 14/686953
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters
C10L 1/1857 (20130101) Original (OR) Class
C10L 10/02 (20130101)
C10L 10/06 (20130101)
C10L 10/10 (20130101)
C10L 2270/02 (20130101)

Internal-combustion Piston Engines; Combustion Engines in General
F02B 47/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261439 Chavez et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Alejandro Chavez (Sharon, Massachusetts);  Johnny Hao Hu (Cambridge, Massachusetts)
ABSTRACT A nucleic acid construct is provided that encodes two or more or a plurality of spacer sequences separated by restriction endonuclease recognition site. A plurality of such nucleic acid sequences are provided as a library for making guide RNAs for use with CRISPR/Cas systems.
FILED Friday, September 16, 2016
APPL NO 15/760372
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/102 (20130101)
C12N 15/1093 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261474 Kacira et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S) Murat Kacira (Tucson, Arizona);  Fei Jia (Tucson, Arizona);  Kimberly L. Ogden (Tucson, Arizona);  Gregory E. Ogden (Tucson, Arizona)
ABSTRACT A multi-wavelength laser diode based optical sensor system capable of monitoring the dynamics and physiological changes of a microorganism culture in real-time. The microorganism culture from a microorganism production chamber is pumped to a flow chamber. Laser diodes emit light at certain wavelengths through the flow chamber, which is sensed by photodiodes. A laser control circuitry is operatively connected to the laser diodes and a signal conditioning circuitry is operatively connected to the photodiodes. A microprocessor reads and records voltage signals corresponding to the wavelengths. A data acquisition system converts said voltage signals into measurements of biological parameters, which are displayed on a graphical user interface and allow a user to monitor the measurements in real time.
FILED Wednesday, June 29, 2016
APPL NO 15/739467
ART UNIT 2877 — Optics
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 21/02 (20130101)
C12M 23/04 (20130101)
C12M 23/18 (20130101)
C12M 29/08 (20130101)
C12M 41/06 (20130101)
C12M 41/36 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261741 Kennedy et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S) Matthew B. Kennedy (Vernon, Connecticut);  Paul F. Croteau (Columbia, Connecticut);  John E. Holowczak (South Windsor, Connecticut);  Thomas J. Martin (East Hampton, Connecticut)
ABSTRACT An airfoil includes an airfoil body that has a trailing edge region. The trailing edge region includes first and second monolithic ceramic exterior walls, a flow discharge passage between the first and second monolithic ceramic exterior walls, a ceramic matrix composite (CMC) liner at least a portion of which is disposed in the flow discharge passage between the first and second monolithic ceramic exterior walls, and an array of pedestals disposed in the flow discharge passage. Each of the flow guides bridges the CMC liner and at least one of the first and second monolithic ceramic exterior walls.
FILED Friday, November 08, 2019
APPL NO 16/678927
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/147 (20130101)
F01D 5/188 (20130101)
F01D 5/282 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2300/6033 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261945 Blackmon et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) James B. Blackmon (Brownsboro, Alabama);  Frederick Gant (Huntsville, Alabama)
ASSIGNEE(S) Board of Trustees of the University of Alabama, for and on behalf of the University of Alabama in Huntsville (Huntsville, Alabama)
INVENTOR(S) James B. Blackmon (Brownsboro, Alabama);  Frederick Gant (Huntsville, Alabama)
ABSTRACT A coupling system can include an energy transfer device and a load mitigation system. The energy transfer device can include a shaft, gear, chain or piston-cylinder arrangement to transfer the energy from a power supply to an object to be moved. The load mitigation system can be used to limit or prevent the transfer of forces from the object to the drive unit as a result of external loads being applied to the object. The load mitigation system can be pre-loaded such that external loads on the object having an excessive impulsive or resonant cyclic force greater than the pre-load force on the load mitigation system are reduced and only partially transferred to the energy transfer device and power supply. The load mitigation system can dampen both resonant loads and impulsive impact loads occurring at the object thereby preventing damage and extending life.
FILED Friday, April 13, 2018
APPL NO 15/953161
ART UNIT 3654 — Material and Article Handling
CURRENT CPC
Springs; Shock-absorbers; Means for Damping Vibration
F16F 15/04 (20130101)
F16F 15/085 (20130101)
F16F 15/1232 (20130101)
F16F 2228/08 (20130101)
F16F 2230/0023 (20130101)

Gearing
F16H 7/0838 (20130101)
F16H 7/1245 (20130101) Original (OR) Class
F16H 2007/087 (20130101)
F16H 2007/088 (20130101)
F16H 2007/0874 (20130101)
F16H 2007/0891 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262074 Berry et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Jonathan Dwight Berry (Simpsonville, South Carolina);  Michael Hughes (State College, Pennsylvania);  Srikanth Chandrudu Kottilingam (Greenville, South Carolina)
ABSTRACT An effusion cooling element for the surface of a hot gas path (HGP) component is disclosed. The effusion cooling element includes a coolant swirling chamber embedded within the body of the HGP component. A coolant delivery passage is in the body and configured to deliver a coolant to the coolant swirling chamber. The coolant swirling chamber imparts a centrifugal force to the coolant. An effusion opening is in the HGP surface and in fluid communication with the coolant swirling chamber, the effusion opening having a smaller width than the coolant swirling chamber. The coolant exits the effusion opening over substantially all of 360° about the effusion opening, creating a coolant film on the HGP surface.
FILED Thursday, March 21, 2019
APPL NO 16/360177
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 9/023 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2240/35 (20130101)
F05D 2260/201 (20130101)
F05D 2260/204 (20130101)

Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers
F23R 3/002 (20130101)
F23R 3/06 (20130101)
F23R 3/007 (20130101)
F23R 3/283 (20130101) Original (OR) Class
F23R 2900/03041 (20130101)
F23R 2900/03042 (20130101)
F23R 2900/03045 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262289 Ohodnicki, Jr. et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
APPLICANT(S) Energy, United States Department of (Washington, District of Columbia)
ASSIGNEE(S) Energy, United States Department of (Washington, District of Columbia)
INVENTOR(S) Paul R. Ohodnicki, Jr. (Allison Park, Pennsylvania);  Malgorzata Ziomek-Moroz (Albany, Oregon)
ABSTRACT Embodiments relate to methods, systems and apparatus for detecting corrosion using a detector apparatus with a host component. The method includes a detector apparatus. The detector apparatus includes an energy source; a corrosion proxy thin film that corrodes at a rate where the normalized change of mass of the film over time is greater than the normalized change of mass of the bulk material of the host component in a harsh environment; and the detector, wherein the detector is capable of detecting a change in energy due to corrosion of the corrosion proxy thin film. The method includes exposing the host component and the corrosion proxy thin film to the harsh environment; and detecting a change in energy using the detector due to corrosion of the corrosion proxy thin film.
FILED Friday, December 30, 2016
APPL NO 15/395018
ART UNIT 2868 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 17/04 (20130101) Original (OR) Class
G01N 21/94 (20130101)
G01N 22/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262320 Kumar et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) UHV Technologies, Inc. (Fort Worth, Texas)
ASSIGNEE(S) UHV Technologies, Inc. (Fort Worth, Texas)
INVENTOR(S) Nalin Kumar (Fort Worth, Texas);  Manuel Gerardo Garcia, Jr. (Lexington, Kentucky)
ABSTRACT A mercury emissions monitor includes a mercury sensor tape configured to be fed in a reel-to-reel manner between first and second tape reels, wherein the mercury sensor tape includes a thin metallic film configured to form an amalgam with detected mercury. A mercury collection unit is configured to receive into a chamber a sample of a gas containing mercury, wherein the mercury collection unit is further configured to permit passage of portions of the mercury sensor tape through the chamber containing the gas sample so that the amalgam is formed with the thin metallic film. A mercury analysis unit includes a total reflection x-ray fluorescence (“TXRF”) system configured to perform a TXRF analysis of the amalgam, wherein the mercury analysis unit is configured to permit passage of the mercury sensor tape within a proximity of an XRF detector of the TXRF system. The mercury collection unit and the mercury analysis unit are positioned between the first and second tape reels so that the mercury sensor tape can move in a continuous manner from the first tape reel through the chamber of the mercury collection unit, then within sufficient proximity to the XRF detector, to be then taken up onto the second tape reel.
FILED Wednesday, August 03, 2016
APPL NO 15/227730
ART UNIT 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/223 (20130101) Original (OR) Class
G01N 23/2202 (20130101)
G01N 23/2204 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262514 Patra et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Susant Patra (Brentwood, California);  Razi-Ul Muhammad Haque (San Francisco, California);  Komal Kampasi (San Francisco, California);  Ian Seth Ladner (Picayune, Mississippi)
ABSTRACT The present disclosure relates to a hybrid opto-electrical module apparatus. The apparatus may have a module substrate having a plurality of electrically conductive circuit traces for carrying electrical signals, and at least one waveguide element for carrying optical signals. A waveguide substrate is in optical communication with the waveguide element. A transducer is supported on the waveguide substrate and in electrical communication with the circuit traces. The waveguide substrate has at least one three dimensional (3D) waveguide formed within its interior volume for routing optical signals between the waveguide element and the transducer. A first optical wirebond interfaces the waveguide element to the 3D waveguide, and a second optical wirebond interfaces the 3D waveguide to the transducer.
FILED Monday, December 09, 2019
APPL NO 16/707764
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/421 (20130101)
G02B 6/4278 (20130101)
G02B 6/4291 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11263443 Brookshire et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) SRI International (Menlo Park, California)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Jonathan D. Brookshire (Princeton, New Jersey);  Supun Samarasekera (Skillman, New Jersey);  Kshitij Singh Minhas (Watchung, New Jersey)
ABSTRACT A method, apparatus and system for human skeleton pose estimation includes synchronously capturing images of a human moving through an area from a plurality of different points of view, for each of the plurality of captured images, determining a bounding box that bounds the human in the captured image and identifying pixel locations of the bounding box in the image, for each of the plurality of captured images, determining 2D and single-view 3D skeletons from the pixel locations of the bounding box, determining a first, multi-view 3D skeleton using a combination of the 2D and single-view 3D skeletons, and optimizing the first, multi-view 3D skeleton to determine a final 3D skeleton pose for the human. The method, apparatus and system can further include illuminating the area with structured light during the capturing of the images of the human moving through the area.
FILED Thursday, May 07, 2020
APPL NO 16/868870
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00348 (20130101) Original (OR) Class
G06K 9/00369 (20130101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)

Image Data Processing or Generation, in General
G06T 7/30 (20170101)
G06T 7/74 (20170101)
G06T 17/20 (20130101)
G06T 2207/10012 (20130101)
G06T 2207/10028 (20130101)
G06T 2207/10048 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/30196 (20130101)
G06T 2210/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11263792 Jimenez, Jr. et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Edward Steven Jimenez, Jr. (Albuquerque, New Mexico);  Srivathsan Prabu Koundinyan (Highland Park, New Jersey);  Isabel Gallegos (Albuquerque, New Mexico);  Adriana Stohn (Chandler, Arizona);  Gabriella Dalton (Albuquerque, New Mexico)
ABSTRACT A calibration method for an x-ray computerized tomography system and a method of tomographic reconstruction are provided. The calibration method includes steps of measuring at least one point spread function (PSF) at each of a plurality of points, compressing each PSF, and in one or more storing operations, storing the compressed PSFs in a computer-accessible storage medium. The PSF measurements are made in a grid of calibration points in a field of view (FOV) of the system. In the measuring step, an absorber is positioned at each of the calibration points, and an x-ray projection is taken at least once at each of those absorber positions. In the method of tomographic image reconstruction, projection data from an x-ray tomographic projection system are input to an iterative image reconstruction algorithm. The algorithm retrieves and utilizes a priori system information (APSI) The APSI comprises comprising point spread functions (PSFs) of all voxels in a voxelization of the field of view that are compressed in the form of vectors of parameters. For utilization, each retrieved vector of parameters is decompressed so as to generate a discretized PSF.
FILED Monday, December 23, 2019
APPL NO 16/725549
ART UNIT 2884 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/032 (20130101)
A61B 6/586 (20130101)
A61B 6/4085 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/046 (20130101)

Image Data Processing or Generation, in General
G06T 11/005 (20130101) Original (OR) Class
G06T 11/006 (20130101)
G06T 2207/10081 (20130101)
G06T 2211/424 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11264179 Zhu et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  Shanghai Jiao Tong University (Shanghai, China PRC)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Kai Zhu (Littleton, Colorado);  Joseph M. Luther (Boulder, Colorado);  Yixin Zhao (Shanghai, China PRC)
ABSTRACT The present disclosure describes solution methods for manufacturing perovskite halide films for use in solar cells. The methods include the use of additives that facilitate the formation of transitory, intermediate films that are later transformed into the final target perovskite halide films, such that the final films provide improved physical characteristics and operational performance.
FILED Thursday, December 05, 2019
APPL NO 16/704207
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 9/2013 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0007 (20130101)
H01L 51/0026 (20130101)
H01L 51/0032 (20130101)
H01L 51/4226 (20130101)
H01L 51/4253 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/549 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 70/50 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11264228 Mannion et al.
FUNDED BY
Department of Energy (DOE)
Office of Environmental Management (DOE-EM)
Savannah River National Laboratory (SRNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Savannah River Nuclear Solutions, LLC (SRNS) at Aiken, SC
APPLICANT(S) Savannah River Nuclear Solutions, LLC (Aiken, South Carolina)
ASSIGNEE(S) Savannah River Nuclear Solutions, LLC (Aiken, South Carolina)
INVENTOR(S) Joseph M. Mannion (Aiken, South Carolina);  Randall M. Achey (New Ellenton, South Carolina)
ABSTRACT A method for modifying a carbon thermal ionization filament is disclosed. In particular, the method requires a step of reacting a fluorine-containing compound with the carbon thermal ionization filament to provide a fluorinated carbon thermal ionization filament. Such method can result in a fluorinated carbon thermal ionization filament that can be employed in a system, such as a thermal ionization mass spectrometer, for ionizing a sample.
FILED Tuesday, October 09, 2018
APPL NO 16/155143
ART UNIT 2879 — Optics
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 32/10 (20170801)
C01B 32/194 (20170801)
C01B 32/198 (20170801)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/4022 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 1/14 (20130101)
H01J 49/16 (20130101) Original (OR) Class
H01J 49/0031 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11264603 Vissers
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) Vissers Battery Corporation (Wheaton, Illinois)
ASSIGNEE(S) Vissers Battery Corporation (Wheaton, Illinois)
INVENTOR(S) Daniel R. Vissers (Wheaton, Illinois)
ABSTRACT A battery includes a fluid negative electrode and a fluid positive electrode separated by a solid electrolyte at least when the electrodes and electrolyte are at an operating temperature. The solid electrolyte includes ions of the negative electrode material forming the fluid negative electrode and has a softness less than beta-alumina solid electrolyte (BASE) ceramics. In one example, the fluid negative electrode comprises lithium (Li), the fluid positive electrode comprises sulfur (S) and the solid electrolyte comprises lithium iodide (LiI).
FILED Thursday, May 17, 2018
APPL NO 15/982475
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/136 (20130101) Original (OR) Class
H01M 4/0471 (20130101)
H01M 4/1397 (20130101)
H01M 10/39 (20130101)
H01M 10/63 (20150401)
H01M 2004/027 (20130101)
H01M 2004/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11264659 Bi et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UChicago Argonne, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Xuanxuan Bi (Naperville, Illinois);  Jun Lu (Naperville, Illinois);  Khalil Amine (Oakbrook, Illinois)
ABSTRACT An electrochemical device includes an air cathode; a lithium-containing anode metal; a porous separator; and a non-aqueous electrolyte comprising a lithium salt, a sodium salt, and a solvent; wherein the electrochemical device is a lithium-air battery. A total concentration of the lithium salt and the sodium salt in the non-aqueous electrolyte may be from about 0.001 M to about 7 M.
FILED Tuesday, August 20, 2019
APPL NO 16/545127
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/134 (20130101)
H01M 4/136 (20130101)
H01M 4/382 (20130101)
H01M 4/386 (20130101)
H01M 4/483 (20130101)
H01M 4/587 (20130101)
H01M 4/622 (20130101)
H01M 4/625 (20130101)
H01M 4/661 (20130101)
H01M 10/052 (20130101)
H01M 10/0562 (20130101)
H01M 10/0568 (20130101)
H01M 10/0569 (20130101)
H01M 12/08 (20130101)
H01M 12/065 (20130101) Original (OR) Class
H01M 50/411 (20210101)
H01M 50/417 (20210101)
H01M 50/431 (20210101)
H01M 50/497 (20210101)
H01M 2004/027 (20130101)
H01M 2004/028 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11264676 Carlson et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Optodot Corporation (Devens, Massachusetts)
ASSIGNEE(S) Optodot Corporation (Devens, Massachusetts)
INVENTOR(S) Steven A. Carlson (Cambridge, Massachusetts);  Ifenna Kingsley Anakor (Allston, Massachusetts);  Greg Robert Farrell (Sudbury, Massachusetts)
ABSTRACT Provided are separators for use in an electrochemical cell comprising (a) an inorganic oxide and (b) an organic polymer, wherein the inorganic oxide comprises organic substituents. Also provided are electrochemical cells comprising such separators.
FILED Thursday, August 19, 2021
APPL NO 17/406515
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 14/303 (20130101)
C04B 24/00 (20130101)
C04B 24/023 (20130101)
C04B 26/06 (20130101)
C04B 38/0074 (20130101)
C04B 2111/00612 (20130101)
C04B 2111/00801 (20130101)
C04B 2111/00853 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 50/409 (20210101)
H01M 50/411 (20210101)
H01M 50/431 (20210101)
H01M 50/446 (20210101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/10 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49115 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11266005 Posen et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Fermi National Accelerator Laboratory (FNAL)
Federally Funded Research and Development Center (FFRDC)
Operated by Fermi Research Alliance, LLC (FRA) at Batavia, IL
APPLICANT(S) FERMI RESEARCH ALLIANCE, LLC (Batavia, Illinois)
ASSIGNEE(S) FERMI RESEARCH ALLIANCE, LLC (Batavia, Illinois)
INVENTOR(S) Sam Posen (Arlington Heights, Illinois);  Anna Grassellino (Batavia, Illinois)
ABSTRACT A system and method for treating a cavity comprises arranging a niobium structure in a coating chamber, the coating chamber being arranged inside a furnace, coating the niobium structure with tin thereby forming an Nb3Sn layer on the niobium structure, and doping the Nb3Sn layer with nitrogen, thereby forming a nitrogen doped Nb3Sn layer on the niobium structure.
FILED Thursday, February 06, 2020
APPL NO 16/784092
ART UNIT 1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 19/00 (20130101)
C01G 33/00 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 16/06 (20130101)
C23C 16/045 (20130101)
C23C 16/4485 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/02 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 39/00 (20130101)
H01L 39/24 (20130101)
H01L 39/2406 (20130101)
H01L 39/2432 (20130101)
H01L 39/2438 (20130101)

Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 7/06 (20130101)
H01P 11/008 (20130101)

Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 7/20 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11259685 Xie et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida)
ASSIGNEE(S) THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida)
INVENTOR(S) Huikai Xie (Gainesville, Florida);  Sanjeev Jagannatha Koppal (Gainesville, Florida);  Xiaoyang Zhang (Alviso, California);  Liang Zhou (Gainesville, Florida);  Can Duan (Dallas, Texas)
ABSTRACT Methods and apparatuses for enlarging the optical scan angle of imaging probes are provided. The optical scan angle of endoscopic probes can be increased by employing the “Snell's Window” effect. An endoscopic probe can include an endoscope shell, a device for capturing electromagnetic radiation, and a liquid or gel provided between the device for capturing electromagnetic radiation and the endoscope shell. The endoscope probe can further include a first mirror placed such that electromagnetic radiation entering through the endoscope shell can bounce off the first mirror and enter the device for capturing electromagnetic radiation. The first mirror can be a microelectromechanical systems (MEMS) mirror.
FILED Friday, July 28, 2017
APPL NO 16/316694
ART UNIT 2872 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/00 (20130101) Original (OR) Class
A61B 1/05 (20130101)
A61B 1/07 (20130101)
A61B 1/042 (20130101)
A61B 1/00096 (20130101)
A61B 1/00165 (20130101)
A61B 1/00172 (20130101)
A61B 1/00177 (20130101)
A61B 1/00183 (20130101)
A61B 1/0638 (20130101)
A61B 1/0684 (20130101)
A61B 5/0066 (20130101)
A61B 2505/05 (20130101)
A61B 2562/028 (20130101)
A61B 2562/168 (20130101)
A61B 2562/0233 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11259740 Bhatnagar et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Research Foundation for The State University of New York (Albany, New York)
ASSIGNEE(S) The Research Foundation for State University of New York (Albany, New York)
INVENTOR(S) Divya Bhatnagar (Stony Brook, New York);  Miriam Rafailovich (Plainview, New York);  Raphael Davis (Port Jefferson, New York);  Alexander B. Dagum (Stony Brook, New York);  Duc T. Bui (Dix Hills, New York)
ABSTRACT The present invention pertains to methods of determining where, on the skin, a diagnostic, therapeutic, or cosmetic agent is likely to be most effectively applied (e.g., injected), and to methods for monitoring a patient after such an agent has been administered. The monitoring can produce information useful in determining whether a diagnostic, therapeutic (e.g., surgical), or cosmetic regime should be initiated, continued, continued in a modified fashion, or terminated (e.g., for a brief or prolonged period of time). The methods can be repeated periodically and use a non-invasive, in vivo form of digital image speckle correlation (DISC) to track deformation of the skin.
FILED Tuesday, April 03, 2018
APPL NO 15/944528
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/442 (20130101) Original (OR) Class
A61B 5/1107 (20130101)
A61B 5/1128 (20130101)
A61B 5/4041 (20130101)
A61B 5/4839 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11259870 DiMaio et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) Intuitive Surgical Operations, Inc. (Sunnyvale, California);  The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) Intuitive Surgical Operations, Inc. (Sunnyvale, California)
INVENTOR(S) Simon P. DiMaio (San Carlos, California);  Christopher J. Hasser (Los Altos, California);  Russell H. Taylor (Severna Park, Maryland);  David Q. Larkin (Menlo Park, California);  Peter Kazanzides (Towson, Maryland);  Anton Deguet (Baltimore, Maryland);  Balazs Peter Vagvolgyi (Baltimore, Maryland);  Joshua Leven (San Francisco, California)
ABSTRACT In one embodiment of the invention, a a minimally invasive surgical system is disclosed. The system configured to capture and display camera images of a surgical site on at least one display device at a surgeon console; switch out of a following mode and into a masters-as-mice (MaM) mode; overlay a graphical user interface (GUI) including an interactive graphical object onto the camera images; and render a pointer within the camera images for user interactive control. In the following mode, the input devices of the surgeon console may couple motion into surgical instruments. In the MaM mode, the input devices interact with the GUI and interactive graphical objects. The pointer is manipulated in three dimensions by input devices having at least three degrees of freedom. Interactive graphical objects are related to physical objects in the surgical site or a function thereof and are manipulatable by the input devices.
FILED Wednesday, October 04, 2017
APPL NO 15/725271
ART UNIT 3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/00193 (20130101)
A61B 8/00 (20130101)
A61B 8/12 (20130101)
A61B 8/4245 (20130101)
A61B 34/10 (20160201) Original (OR) Class
A61B 34/25 (20160201)
A61B 34/30 (20160201)
A61B 34/37 (20160201)
A61B 34/70 (20160201)
A61B 34/71 (20160201)
A61B 34/76 (20160201)
A61B 90/361 (20160201)
A61B 2017/00203 (20130101)
A61B 2090/365 (20160201)
A61B 2090/378 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260121 Steinmetz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Nicole F. Steinmetz (Cleveland, Ohio);  Amy M. Wen (Cleveland, Ohio);  Steven Fiering (Cleveland, Ohio);  Patrick H. Lizotte (Cleveland, Ohio)
ABSTRACT A method of treating cancer in a subject in need thereof includes administering in situ to the cancer a therapeutically effective amount of a virus or virus-like particle.
FILED Friday, April 17, 2020
APPL NO 16/851778
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/704 (20130101)
A61K 39/12 (20130101) Original (OR) Class
A61K 2039/544 (20130101)
A61K 2039/585 (20130101)
A61K 2039/5258 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
A61P 35/04 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2770/00023 (20130101)
C12N 2770/00034 (20130101)
C12N 2770/00071 (20130101)
C12N 2770/32022 (20130101)
C12N 2770/32023 (20130101)
C12N 2770/32034 (20130101)
C12N 2770/32071 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260358 Lee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Daeyeon Lee (Wynnewood, Pennsylvania);  Kathleen J. Stebe (Penn Valley, Pennsylvania);  Sarah D. Hann (Yardley, Pennsylvania)
ABSTRACT In one aspects of the invention, a microcapsule includes a film encapsulating a material. The film is formed by complexation of at least two mutually attractive components initially present in an aqueous dispersion comprising a continuous phase and a dispersed phase. The at least one first component is initially present in the continuous phase and the at least one second component is initially present in the dispersed phase. According to another aspect of the invention, provided is a process for forming microcapsules including the step of injecting a dispersed phase having at least a first component into a continuous phase having at least a second component, where the first component and the second component are mutually attractive, such that a film is formed by complexation of the first charged component and the second charged component.
FILED Friday, April 13, 2018
APPL NO 15/952321
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5031 (20130101)
A61K 9/5036 (20130101)
A61K 35/74 (20130101)
A61K 2035/128 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 13/04 (20130101)
B01J 13/10 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 11/04 (20130101)
C12N 11/10 (20130101)
C12N 11/082 (20200101)
C12N 11/087 (20200101)
C12N 11/089 (20200101)
C12N 11/098 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260379 Coates et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Geoffrey W. Coates (Lansing, New York);  Brooks Abel (McComb, Mississippi);  Claire Lidston (Ithaca, New York)
ABSTRACT Provided are catalysts, methods of making catalysts, methods of using catalysts, and copolymers made utilizing the catalysts. The catalyst has a metal salen complex group, a bridging group, and one or more co-catalyst groups. The metal salen complex group is attached to the bridging group and the bridging group is attached to the co-catalyst group. The copolymers made utilizing the catalysts are polyesters or polycarbonates.
FILED Wednesday, June 10, 2020
APPL NO 16/898377
ART UNIT 1738 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/143 (20130101) Original (OR) Class
B01J 2531/0252 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 63/42 (20130101)
C08G 63/84 (20130101)
C08G 64/02 (20130101)
C08G 64/34 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260586 Fink et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Yoel Fink (Brookline, Massachusetts);  Gabriel Zi Jie Loke (Cambridge, Massachusetts);  Rodger Yuan (Boston, Massachusetts)
ABSTRACT In a method for printing a three dimensional structure, a continuous length of fiber that includes, interior to a surface of the fiber, a plurality of different materials arranged as an in-fiber functional domain, with at least two electrical conductors disposed in the functional domain in electrical contact with at least one functional domain material, is dispensed through a single heated nozzle. After sections of the length of fiber are dispensed from the heated nozzle, the sections are fused together in an arrangement of a three dimensional structure. The structure can thereby include a continuous length of fiber of least three different materials arranged as an in-fiber functional device, with the continuous length of fiber disposed as a plurality of fiber sections that are each in a state of material fusion with another fiber section in a spatial arrangement of the structure.
FILED Friday, November 17, 2017
APPL NO 15/816964
ART UNIT 1786 — Miscellaneous Articles, Stock Material
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/118 (20170801)
B29C 64/209 (20170801) Original (OR) Class
B29C 70/88 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2101/12 (20130101)
B29K 2827/18 (20130101)
B29K 2905/12 (20130101)
B29K 2995/0005 (20130101)
B29K 2995/0013 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/34 (20130101)
B29L 2031/3468 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 80/00 (20141201)

Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 7/16 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 7/0233 (20130101)
H01B 7/0275 (20130101)
H01B 13/14 (20130101)
H01B 13/0016 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/032 (20130101)
H01L 31/0203 (20130101)
H01L 41/23 (20130101)
H01L 41/0533 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/386 (20130101)
H01M 4/387 (20130101)
H01M 4/505 (20130101)
H01M 4/525 (20130101)
H01M 4/587 (20130101)
H01M 4/5825 (20130101)
H01M 10/058 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 33/04 (20130101)
H05B 33/10 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 5/065 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260642 Shan et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Board of Regents of the Nevada System of Ed., on behalf of the Univ. of Nevada, Reno (Reno, Nevada);  The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) Board of Regents of the Nevada System of Higher Education, on behalf of the University of Nevada, Reno (Reno, Nevada);  The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Wanliang Shan (Reno, Nevada);  Kevin Turner (Wayne, Pennsylvania)
ABSTRACT Disclosed herein are embodiments of methods that utilize dry adhesion tuning of a composite structure to adhere substrates. In some embodiments, the disclosed methods utilize dry adhesion between a composite structure and a substrate and further dynamically control the resulting dry adhesion strength through a heating step, which facilitates rigidity tuning of a core component of the composite structure and/or facilitates thermal control of the interface between the substrate and the composite structure. Also disclosed herein are array devices and other products comprising the disclosed composite structures.
FILED Wednesday, January 31, 2018
APPL NO 16/482601
ART UNIT 1759 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 7/12 (20130101)
B32B 37/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261208 Morrow et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) The Research Foundation for The State University of New York (Buffalo, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Amherst, New York)
INVENTOR(S) Janet R. Morrow (Williamsville, New York);  Eric M. Snyder (Williamsville, New York);  Didar Asik (Buffalo, New York)
ABSTRACT Provided are macrocyclic compounds and compounds with two or more macrocyclic groups, iron coordinated macrocyclic compounds, and iron coordinated compounds with two or more macrocyclic groups. The iron is high-spin iron(III). The iron coordinated compounds may exhibit a negative redox potential (e.g., relative to a normal hydrogen electrode at a biologically relevant pH, for example, a pH of 6.5-7.5). The compounds can be used as MRI contrast agents.
FILED Monday, May 21, 2018
APPL NO 16/615024
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/085 (20130101)
A61K 49/106 (20130101)
A61K 49/124 (20130101)
A61K 49/128 (20130101)
A61K 49/143 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 15/025 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261471 Rome et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) The Regents of the University of California (Oakland, California);  Vault Pharma Inc. (Los Angeles, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  Vault Pharma Inc. (Los Angeles, California)
INVENTOR(S) Leonard H. Rome (Tarzana, California);  Shaily Mahendra (Santa Monica, California);  Meng Wang (Los Angeles, California);  Valerie A. Kickhoefer (Sherman Oaks, California);  Oliver Karl Foellmer (Santa Monica, California)
ABSTRACT Disclosed herein are methods and compositions for making vault particles in yeast hosts and yeast vaults produced therefrom.
FILED Thursday, May 16, 2019
APPL NO 16/414465
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle
A61J 3/00 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 47/00 (20130101)
A61K 47/42 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Peptides
C07K 14/47 (20130101)
C07K 2319/00 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 21/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262286 Ozcan et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Aydogan Ozcan (Los Angeles, California);  Yichen Wu (Los Angeles, California)
ABSTRACT A label-free bio-aerosol sensing platform and method uses a field-portable and cost-effective device based on holographic microscopy and deep-learning, which screens bio-aerosols at a high throughput level. Two different deep neural networks are utilized to rapidly reconstruct the amplitude and phase images of the captured bio-aerosols, and to output particle information for each bio-aerosol that is imaged. This includes, a classification of the type or species of the particle, particle size, particle shape, particle thickness, or spatial feature(s) of the particle. The platform was validated using the label-free sensing of common bio-aerosol types, e.g., Bermuda grass pollen, oak tree pollen, ragweed pollen, Aspergillus spore, and Alternaria spore and achieved >94% classification accuracy. The label-free bio-aerosol platform, with its mobility and cost-effectiveness, will find several applications in indoor and outdoor air quality monitoring.
FILED Friday, April 24, 2020
APPL NO 16/858444
ART UNIT 2886 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/0227 (20130101) Original (OR) Class
G01N 2015/0233 (20130101)

Holographic Processes or Apparatus
G03H 1/0443 (20130101)
G03H 1/2294 (20130101)
G03H 2001/0447 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/0454 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 7/62 (20170101)
G06T 2207/10056 (20130101)
G06T 2207/20084 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262352 Vemulapati et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Sasank Vemulapati (Ithaca, New York);  David Erickson (Ithaca, New York)
ABSTRACT The present disclosure relates to, inter alia, devices, systems, and methods for use in the magnetic separation of biological entities from fluid samples. This device includes a magnetic separation chamber configured to receive a fluid sample for magnetic separation, where the magnetic separation chamber includes at least two magnets mounted on the surface or in the wall of the magnetic separation chamber. The device also includes a force provider configured to move the magnetic separation chamber in a side-to-side motion to mix and/or magnetize the fluid sample. In one embodiment, the magnetic separation chamber is in a form of a sleeve and comprises a substantially central channel for loading a vessel containing the fluid sample therein. The systems and methods of the present disclosure involve the use of this device to separate biological entities from fluid samples.
FILED Monday, July 22, 2019
APPL NO 17/261855
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/4077 (20130101)
G01N 33/54326 (20130101) Original (OR) Class
G01N 33/56966 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262361 Tibbitt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Mark W. Tibbitt (Boulder, Colorado);  Kristi S. Anseth (Boulder, Colorado);  April M. Kloxin (Boulder, Colorado);  Mehmet Toner (Boulder, Colorado);  John Oakey (Boston, Massachusetts);  Ajay Shah (Boston, Massachusetts)
ABSTRACT Disclosed herein are photodegradable hydrogels and associated kits for selectively capturing and releasing cells. The hydrogels result from cross linking in the presence of a photoinitiator (1) a macromer having a polymeric backbone structure, a photo labile moiety, and a first linking moiety, and (2) a cell-binding moiety having a second linking moiety. These two components are cross-linked by a polymerization reaction of the linking moieties to form a photodegradable hydrogel incorporating the cell-binding moiety within the hydrogel. Also disclosed are methods of making the hydrogels, and methods of using the hydrogels for selectively capturing and releasing cells and for detecting cells in a fluid. Such methods can be used to detect the presence and quantity of certain rare cell types in a biological fluid.
FILED Friday, July 18, 2014
APPL NO 14/905460
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 41/0028 (20130101)
A61K 47/34 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502761 (20130101)
B01L 2200/0647 (20130101)
B01L 2300/16 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 222/22 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 47/02 (20130101)
C12M 47/04 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/531 (20130101)
G01N 33/54366 (20130101)
G01N 33/56966 (20130101)
G01N 33/57492 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262570 Maddox et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S) THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina)
INVENTOR(S) Paul Samuel Maddox (Chapel Hill, North Carolina);  Tanner Christian Fadero (Chapel Hill, North Carolina)
ABSTRACT Methods for imaging a sample using fluorescence microscopy, systems for imaging a sample using fluorescence microscopy, and illumination systems for fluorescence microscopes. In some examples, a method includes positioning a dual convex paraboloidal mirror enclosure around the sample. The dual convex paraboloidal mirror enclosure includes an upper paraboloidal mirror and a lower paraboloidal mirror oriented antiparallel to each other. An aperture is defined in the lower paraboloidal mirror, a hemispherical dome is mounted in the aperture, and the sample is surrounded by the hemispherical dome. The method includes directing excitation light onto the sample to form a primary image at an upper vertex of the upper paraboloidal mirror and a secondary image at a lower vertex of the lower paraboloidal minor. The method includes imaging the sample through a detection objective of a microscope.
FILED Tuesday, March 12, 2019
APPL NO 16/980231
ART UNIT 2488 — Recording and Compression
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6458 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/08 (20130101)
G02B 21/16 (20130101)
G02B 21/365 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262640 Halasyamani et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) University of Houston System (Houston, Texas)
ASSIGNEE(S) UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas)
INVENTOR(S) P. Shiv Halasyamani (Houston, Texas);  Hongwei Yu (Houston, Texas);  Hongping Wu (Houston, Texas);  Weiguo Zhang (Houston, Texas)
ABSTRACT A device comprising a nonlinear optical (NLO) material according to the formula XLi2Al4B6O20F. A device comprising a nonlinear optical material (NLO) according to the formula KSrCO3F, wherein the NLO comprises at least one single crystal. A nonlinear optical material selected from the group consisting of KSrCO3F Rb3Ba3Li2Al4B6O20F and K3Sr3Li2Al4B6O20F.
FILED Friday, March 09, 2018
APPL NO 16/492261
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals
C01F 7/54 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/20 (20130101)
C01P 2002/60 (20130101)
C01P 2002/80 (20130101)
C01P 2004/61 (20130101)

Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 29/12 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/3551 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11263409 Zhang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
ASSIGNEE(S) BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan)
INVENTOR(S) Mi Zhang (Okemos, Michigan);  Biyi Fang (Lansing, Michigan)
ABSTRACT A sign language translation system may capture infrared images of the formation of a sign language sign or sequence of signs. The captured infrared images may be used to produce skeletal joints data that includes a temporal sequence of 3D coordinates of skeletal joints of hands and forearms that produced the sign language sign(s). A hierarchical bidirectional recurrent neural network may be used to translate the skeletal joints data into a word or sentence of a spoken language. End-to-end sentence translation may be performed using a probabilistic connectionist temporal classification based approach that may not require pre-segmentation of the sequence of signs or post-processing of the translated sentence.
FILED Monday, November 05, 2018
APPL NO 16/181005
ART UNIT 2677 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory
CURRENT CPC
Electric Digital Data Processing
G06F 40/55 (20200101) Original (OR) Class

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00355 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/0445 (20130101)
G06N 3/0454 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11264047 Roy et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Nirupam Roy (Champaign, Illinois);  Romit Roy Choudhury (Champaign, Illinois);  Haitham Al Hassanieh (Champaign, Illinois)
ABSTRACT A voice enabled device includes a transducer to capture multiple inaudible signals received from multiple ultrasonic speakers and audio recording electronics to process the multiple inaudible signals to generate digital output samples, which are recorded sound data comprising non-linearities from frequency-shifted versions of the multiple inaudible signals to within an audible frequency range. A processing device is to detect, within the recorded sound data, at least a portion of the non-linearities, e.g., via: comparison of the recorded sound data with expected patterns from an audible audio signal generated by human voice; and detection of non-linear variations within the recorded sound data as compared to the expected patterns. In response to the detection, the processing device is further to suppress an action programmed for response to a voice command corresponding to the recorded sound data.
FILED Friday, April 24, 2020
APPL NO 16/858200
ART UNIT 2654 — Audio Signals
CURRENT CPC
Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General
B06B 1/0292 (20130101)

Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for
G10K 9/122 (20130101)
G10K 11/178 (20130101)
G10K 15/02 (20130101)

Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding
G10L 21/06 (20130101) Original (OR) Class

Transmission
H04B 1/04 (20130101)
H04B 1/20 (20130101)

Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems
H04R 1/40 (20130101)
H04R 1/323 (20130101)
H04R 27/00 (20130101)
H04R 2217/03 (20130101)
H04R 2227/003 (20130101)
H04R 2227/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11265627 Proietti et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Roberto Proietti (Davis, California);  Sung-Joo Ben Yoo (Davis, California)
ABSTRACT The disclosed system implements a bandwidth-reconfigurable optical interconnect, which couples optical signals between N interconnect inputs and N interconnect outputs. The system includes an arrayed waveguide grating router (AWGR), which provides cyclic, single-wavelength, all-to-all routing between N AWGR inputs and N AWGR outputs. The system also includes a wavelength-insensitive switch, which provides all-wavelength, all-to-all connectivity between N wavelength-insensitive inputs and N wavelength-insensitive outputs. The system additionally includes a wavelength-selective input switch, which selectively directs up to L wavelengths from each of the N interconnect inputs into a corresponding input of the wavelength-insensitive switch, wherein unselected wavelengths from each of the N interconnect inputs pass into a corresponding AWGR input. Finally, the system includes a wavelength-selective output switch, which selectively directs up to L wavelengths from each of the N wavelength-insensitive outputs into a corresponding interconnect output, wherein each of the N AWGR outputs pass into a corresponding interconnect output.
FILED Wednesday, September 25, 2019
APPL NO 16/582902
ART UNIT 2637 — Optical Communications
CURRENT CPC
Multiplex Communication
H04J 14/0212 (20130101)

Selecting
H04Q 11/0005 (20130101) Original (OR) Class
H04Q 11/0066 (20130101)
H04Q 2011/0032 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11265717 Traynor et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Patrick G. Traynor (Gainesville, Florida);  Christian Peeters (Gainesville, Florida);  Bradley G. Reaves (Raleigh, North Carolina);  Hadi Abdullah (Gainesville, Florida);  Kevin Butler (Gainesville, Florida);  Jasmine Bowers (Gainesville, Florida);  Walter N. Scaife (Gainesville, Florida)
ABSTRACT Disclosed are various embodiments for detecting Signaling System 7 (SS7) redirection attacks by measuring call audio round trip times between phones. Such redirection attacks force calls to travel longer physical distances than usual, thereby causing longer end-to-end delay. Accordingly, various embodiments implement a distance bounding-inspired protocol that allows for securely characterizing the round trip time between two call endpoints. As a result, telephone users can reliably detect SS7 redirection attacks and protect the information contained in their calls.
FILED Tuesday, March 19, 2019
APPL NO 16/357998
ART UNIT 2496 — Optical Communications
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/3271 (20130101)

Telephonic Communication
H04M 3/2281 (20130101)

Wireless Communication Networks
H04W 12/50 (20210101)
H04W 12/121 (20210101) Original (OR) Class
H04W 12/0433 (20210101)
H04W 64/006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11260589 Townsend et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
John F. Kennedy Space Center (KSC)
APPLICANT(S) Craig Technologies Aerospace Solutions, LLC (Merritt Island, Florida)
ASSIGNEE(S) Sidus Space, Inc. (Merritt Island, Florida)
INVENTOR(S) Ivan Townsend (Kennedy Space Center, Florida);  Robert Mueller (Kennedy Space Center, Florida);  Nathan Gelino (Kennedy Space Center, Florida);  Jonathan Smith (Kennedy Space Center, Florida);  Matthew Nugent (Kennedy Space Center, Florida);  Andrew Nick (Kennedy Space Center, Florida);  Jason Schuler (Kennedy Space Center, Florida);  Bradley Buckles (Kennedy Space Center, Florida)
ABSTRACT A three-dimensional print head apparatus including a securing mechanism, a hopper, a nozzle, a barrel, and a heating system. The securing mechanism is adapted to secure to a wrist joint of a robotic arm. The hopper is secured to the securing mechanism and has a cavity and a lower aperture. The nozzle has an upper aperture and a lower aperture. The barrel has an elongate, hollow member with a first end secured to the lower aperture of the hopper and a second end secured to the upper aperture of the nozzle. The heating system is positioned along the barrel.
FILED Friday, October 18, 2019
APPL NO 16/656743
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/118 (20170801)
B29C 64/209 (20170801) Original (OR) Class
B29C 64/329 (20170801)
B29C 64/364 (20170801)
B29C 64/393 (20170801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 30/00 (20141201)
B33Y 50/02 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11260995 Bland
FUNDED BY
Department of State (DOS)
National Aeronautics and Space Administration (NASA)
John F. Kennedy Space Center (KSC)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) THE BOEING COMPANY (Chicago, Illinois)
INVENTOR(S) Mitchell C. Bland (Houston, Texas)
ABSTRACT A multi-layer shell structure for a vehicle and method of providing a multi-layer shell structure for a vehicle. The multi-layer structure includes a thermal protection system (TPS) layer, a structural layer connected to the TPS layer, and a high tensile fabric barrier layer bonded to the structural layer. Room-temperature-vulcanizing silicone may be used to bond the TPS layer to the structural layer and bond the high tensile fabric barrier layer to the structural layer. The high tensile fabric barrier layer may create a seal on the structural layer. The multi-layer shell structure may include inner shell enclosing a passenger and/or cargo compartment and an annulus between the inner shell and the high tensile fabric barrier layer. The high tensile fabric barrier layer may prohibit entry of gas into the annulus in the event a hole is created through a portion of the multi-layer shell structure.
FILED Monday, October 29, 2018
APPL NO 16/173821
ART UNIT 1784 — Miscellaneous Articles, Stock Material
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 3/12 (20130101)
B32B 5/024 (20130101)
B32B 5/26 (20130101)
B32B 7/12 (20130101)
B32B 15/00 (20130101)

Aeroplanes; Helicopters
B64C 1/40 (20130101)

Cosmonautics; Vehicles or Equipment Therefor
B64G 1/12 (20130101) Original (OR) Class
B64G 1/14 (20130101)
B64G 1/62 (20130101)

Mining or Quarrying
E21C 51/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261335 Hasegawa et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Mark M. Hasegawa (Highland, Maryland);  Kenneth O'Connor (Greenbelt, Maryland);  Grace M. Miller (Greenbelt, Maryland);  Alfred Wong (Greenbelt, Maryland);  George M. Harris (Greenbelt, Maryland)
ABSTRACT A method of making a thermal control coating is provided. A primer layer can be applied to a substrate to form an exposed surface. The primer layer can include an epoxy binder and a silica filler. The exposed surface can be treated with an oxygen plasma to form a treated surface. A silicate-based thermal control coating can be applied to the treated surface, for example, by spraying, to form a thermal control coating on the substrate. Spacecraft and spacecraft hardware components coated with the thermal control coating, are also provided.
FILED Tuesday, September 25, 2018
APPL NO 16/140878
ART UNIT 1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 3/148 (20130101)

Cosmonautics; Vehicles or Equipment Therefor
B64G 1/58 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 7/0423 (20200101)
C08J 2379/08 (20130101)
C08J 2463/00 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 1/00 (20130101) Original (OR) Class
C09D 5/00 (20130101)
C09D 5/002 (20130101)
C09D 163/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262301 Hug et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Office (CCDC ARO)
National Aeronautics and Space Administration (NASA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Photon Systems, Inc. (Covina, California)
ASSIGNEE(S) Photon Systems, Inc. (Covina, California)
INVENTOR(S) William F. Hug (Altadena, California);  Rohit Bhartia (Pasadena, California);  Ray D. Reid (Glendora, California);  Arthur L. Lane (Arcadia, California)
ABSTRACT Naphthalene, benzene, toluene, xylene, and other volatile organic compounds VOCs have been identified as serious health hazards. Embodiments of the invention are directed to methods and apparatus for near-real-time in-situ detection and accumulated dose measurement of exposure to naphthalene vapor and other hazardous gaseous VOCs. The methods and apparatus employ excitation of fluorophors native or endogenous to compounds of interest using light sources emitting in the ultraviolet below 300 nm and measurement of native fluorescence emissions in distinct wavebands above the excitation wavelength. The apparatus of some embodiments are cell-phone-sized sensor/dosimeter “badges” to be worn by personnel potentially exposed to hazardous VOCs. The badge sensor of some embodiments provides both real time detection and data logging of exposure to naphthalene or other VOCs of interest from which both instantaneous and accumulated dose can be determined.
FILED Friday, September 04, 2020
APPL NO 17/013469
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/10 (20130101)
G01J 3/36 (20130101)
G01J 3/44 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/64 (20130101) Original (OR) Class
G01N 21/65 (20130101)
G01N 21/6486 (20130101)
G01N 21/8806 (20130101)
G01N 27/44721 (20130101)
G01N 33/0047 (20130101)
G01N 2021/6421 (20130101)
G01N 2021/6471 (20130101)
G01N 2201/062 (20130101)
G01N 2201/126 (20130101)
G01N 2201/0612 (20130101)
G01N 2201/06113 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11262489 Hasegawa et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Mark M. Hasegawa (Highland, Maryland);  Kenneth O'Connor (Greenbelt, Maryland);  Grace M. Miller (Greenbelt, Maryland);  Alfred Wong (Greenbelt, Maryland);  George M. Harris (Greenbelt, Maryland)
ABSTRACT A method of making a multi-layer coating on a substrate is provided and involves applying a mirror coating to a substrate then spraying a silicate topcoat onto the mirror coating. Applying the mirror coating can involve applying a reflective material to the substrate to form a reflective layer and applying an oxide layer to the reflective layer to form the mirror coating. The oxide layer can be made of one or more oxide layers, and each of the one or more oxide layers can include aluminum oxide, silicon oxide, or a combination thereof. The multi-layer coating provides increased IR emittance and decreased solar absorptance relative to conventional thermal control coatings.
FILED Wednesday, September 19, 2018
APPL NO 16/135392
ART UNIT 1759 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/50 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 28/42 (20130101)
C23C 28/321 (20130101)

Optical Elements, Systems, or Apparatus
G02B 5/0875 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 11262785 Monroe et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Security Agency (NSA)
Maryland Procurement Office (MPO)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland)
INVENTOR(S) Christopher Monroe (Ellicott City, Maryland);  Jiehang Zhang (College Park, Maryland);  David Wong-Campos (Hyattsville, Maryland);  Antonios Kyprianidis (Takoma, Maryland);  Patrick Michael Becker (College Park, Maryland)
ABSTRACT The disclosure describes an adaptive and optimal imaging of individual quantum emitters within a lattice or optical field of view for quantum computing. Advanced image processing techniques are described to identify individual optically active quantum bits (qubits) with an imager. Images of individual and optically-resolved quantum emitters fluorescing as a lattice are decomposed and recognized based on fluorescence. Expected spatial distributions of the quantum emitters guides the processing, which uses adaptive fitting of peak distribution functions to determine the number of quantum emitters in real time. These techniques can be used for the loading process, where atoms or ions enter the trap one-by-one, for the identification of solid-state emitters, and for internal state-detection of the quantum emitters, where each emitter can be fluorescent or dark depending on its internal state. This latter application is relevant to efficient and fast detection of optically active qubits in quantum simulations and quantum computing.
FILED Thursday, January 03, 2019
APPL NO 16/239084
ART UNIT 2878 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)
B82Y 40/00 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 1/42 (20130101)
G01J 2001/4247 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6458 (20130101)

Optical Computing Devices;
G06E 3/005 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/66977 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11265012 Comar
FUNDED BY
National Security Agency (NSA)
APPLICANT(S) The Government of the United States as represented by the Director, National Security Agency (Ft. George G. Meade, Maryland)
ASSIGNEE(S) U.S. Government as represented by the Director, National Security Agency (Washington, District of Columbia)
INVENTOR(S) Bradley B. Comar (Washington, District of Columbia)
ABSTRACT A method of transmitting a message includes, for each data block, generating a root matrix using a generator, generating a quasi-cyclic matrix H using the root matrix, encoding the block using H to create a codeword, and transmitting the codeword. The root matrix includes three submatrices: an identity matrix in an upper-left-hand portion of the root matrix, an identity matrix in a lower-left-hand portion of the root matrix, and a circulant matrix in a right-hand portion of the root matrix. The circulant matrix equals the sum of an identity matrix and an identity matrix with rows shifted once to the right. Generating H includes expanding the root matrix by replacing 0 elements in the root matrix by a square matrix of 0 elements and replacing 1 elements in the root matrix by a shifted diagonal matrix. Non-zero elements of the diagonal matrix are selected from GF(q) based on the generator.
FILED Wednesday, December 23, 2020
APPL NO 17/132559
ART UNIT 2111 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Coding; Decoding; Code Conversion in General
H03M 13/616 (20130101)
H03M 13/1102 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/0656 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11265627 Proietti et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Roberto Proietti (Davis, California);  Sung-Joo Ben Yoo (Davis, California)
ABSTRACT The disclosed system implements a bandwidth-reconfigurable optical interconnect, which couples optical signals between N interconnect inputs and N interconnect outputs. The system includes an arrayed waveguide grating router (AWGR), which provides cyclic, single-wavelength, all-to-all routing between N AWGR inputs and N AWGR outputs. The system also includes a wavelength-insensitive switch, which provides all-wavelength, all-to-all connectivity between N wavelength-insensitive inputs and N wavelength-insensitive outputs. The system additionally includes a wavelength-selective input switch, which selectively directs up to L wavelengths from each of the N interconnect inputs into a corresponding input of the wavelength-insensitive switch, wherein unselected wavelengths from each of the N interconnect inputs pass into a corresponding AWGR input. Finally, the system includes a wavelength-selective output switch, which selectively directs up to L wavelengths from each of the N wavelength-insensitive outputs into a corresponding interconnect output, wherein each of the N AWGR outputs pass into a corresponding interconnect output.
FILED Wednesday, September 25, 2019
APPL NO 16/582902
ART UNIT 2637 — Optical Communications
CURRENT CPC
Multiplex Communication
H04J 14/0212 (20130101)

Selecting
H04Q 11/0005 (20130101) Original (OR) Class
H04Q 11/0066 (20130101)
H04Q 2011/0032 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11260050 Moran
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) UNIVERSIDAD SAN SEBASTIAN (Concepcion, Chile)
ASSIGNEE(S) UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia);  UNIVERSIDAD SAN SEBASTIAN (Concepcion, Chile)
INVENTOR(S) Valentina Echeverria Moran (Largo, Florida)
ABSTRACT The present invention relates to a method of a) treating any of depression induced by chronic stress; depression in a subject afflicted with PTSD; anxiety induced by chronic stress; anxiety in a subject afflicted with PTSD; cognitive impairment induced by chronic stress; altered morphology and/or reduced number of GFAP+ cells in hippocampus and/or frontal cortex induced by chronic stress; working memory impairment in a subject afflicted with PTSD; b) inhibiting or reversing loss of GFAP+ cells in hippocampus and/or frontal cortex induced by chronic stress; c) decreasing consolidation of contextual fear memory in a subject afflicted with PTSD; d) enhancing extinction of fear memory in a subject afflicted with PTSD; or e) increasing calcineurin A expression in a subject afflicted with PTSD using a combination of cotinine and an antioxidant.
FILED Friday, February 16, 2018
APPL NO 16/486498
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0043 (20130101)
A61K 9/0053 (20130101)
A61K 9/127 (20130101)
A61K 31/202 (20130101)
A61K 31/4439 (20130101) Original (OR) Class
A61K 35/612 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/22 (20180101)
A61P 25/24 (20180101)
A61P 25/28 (20180101)
A61P 39/06 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11261152 Rettig et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of California (Oakland, California);  The United States Government represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Matthew Rettig (Los Angeles, California);  Michael E. Jung (Los Angeles, California);  D. Elshan Nakath G. Ralalage (Los Angeles, California);  Jiabin An (Los Angeles, California)
ABSTRACT The present disclosure provides compounds and methods for inhibiting or degrading the N-terminal domain of the androgen receptor, as well as methods for treating cancers such as prostate cancer.
FILED Friday, January 19, 2018
APPL NO 16/478914
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Acyclic or Carbocyclic Compounds
C07C 33/486 (20130101)
C07C 49/223 (20130101)
C07C 225/16 (20130101) Original (OR) Class
C07C 235/34 (20130101)
C07C 235/78 (20130101)
C07C 321/20 (20130101)

Heterocyclic Compounds
C07D 207/08 (20130101)
C07D 211/32 (20130101)
C07D 241/04 (20130101)
C07D 265/30 (20130101)
C07D 303/32 (20130101)
C07D 303/40 (20130101)
C07D 307/52 (20130101)
C07D 333/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 11261308 Cai et al.
FUNDED BY
Department of Agriculture (USDA)
U.S. Forest Service (FS)
APPLICANT(S) Zhiyong Cai (Madison, Wisconsin);  Qiangu Yan (Madison, Wisconsin);  Jinghao Li (Madison, Wisconsin)
ASSIGNEE(S)
INVENTOR(S) Zhiyong Cai (Madison, Wisconsin);  Qiangu Yan (Madison, Wisconsin);  Jinghao Li (Madison, Wisconsin)
ABSTRACT Methods of making self-expended lignofoams are provided. In embodiments, such a method comprises exposing a self-expanding lignofoam composition comprising raw lignin and a thermoplastic polymer to an elevated temperature for a period of time to soften the composition, desorb water from the raw lignin or induce at least some hydroxyl groups of the raw lignin to undergo dehydration reactions to generate water or both, vaporize the water, and generate pores throughout the softened composition. The method further comprises cooling the porous, softened composition to room temperature to provide the self-expanded lignofoam. The self-expanding lignofoam composition is free of an added plasticizer, an added lubricant, an added foaming agent, and an added blowing agent, and the thermoplastic polymer is not a starch, not a polyurethane, and not a polysiloxane. The resulting self-expanded lignofoams are also provided.
FILED Tuesday, April 23, 2019
APPL NO 16/391424
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 9/02 (20130101)
C08J 9/06 (20130101) Original (OR) Class
C08J 2201/03 (20130101)
C08J 2203/10 (20130101)
C08J 2397/00 (20130101)
C08J 2423/06 (20130101)
C08J 2423/12 (20130101)
C08J 2433/12 (20130101)
C08J 2433/20 (20130101)
C08J 2469/00 (20130101)
C08J 2471/02 (20130101)

Compositions of Macromolecular Compounds
C08L 97/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 11261181 Zang et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Ling Zang (Salt Lake City, Utah);  Paul Slattum (Salt Lake City, Utah)
ABSTRACT Methods of detecting a non-explosive analyte can include exposing a sensor compound to a non-explosive analyte and displaying a change in the sensor compound upon exposure of the sensor compound to the non-explosive analyte. A variety of sensor compounds for detecting a target analyte, including both explosive and non-explosive analytes, is also described. Sensor devices for detecting a target analyte can include a substrate and a sensor compound positioned on the substrate in a plurality of detection zones.
FILED Monday, July 11, 2016
APPL NO 15/743259
ART UNIT 1796 — Organic Chemistry
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Heterocyclic Compounds
C07D 221/18 (20130101)
C07D 471/04 (20130101) Original (OR) Class
C07D 491/052 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/643 (20130101)
G01N 27/126 (20130101)
G01N 2021/6432 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Justice (DOJ) 

US 11262155 Vabnick
FUNDED BY
Department of Justice (DOJ)
Federal Bureau of Investigation (FBI)
APPLICANT(S) Federal Bureau of Investigation (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as Represented by the Federal Bureau of Investigation, Department of Justice (Washington, District of Columbia)
INVENTOR(S) Ian B. Vabnick (Quantico, Virginia)
ABSTRACT A propellant driven disrupter (PDD) for disrupting an explosive target, comprising: a disrupter barrel having a breech and muzzle end; a projectile liquid or gas positioned in the barrel and extending a longitudinal distance in the disrupter barrel. The projectile liquid distal end is located farthest from the disrupter barrel breech end. A jet stabilizing projectile (JSP) is at least partially positioned in the barrel and operably contacts the projectile liquid distal end. The JSP has a JSP proximal end facing toward the disrupter barrel breech end and a distal end opposed to the JSP proximal end, wherein some or all of the JSP is positioned in the barrel. The PDD may contain the JSP, with an air region between the JSP distal end and the muzzle end, or an air region in an adapter that is connected to the muzzle end. Also provided are JSP's having improved flight stability for use with liquid or air-filled disrupters and methods of disrupting a target.
FILED Friday, August 07, 2020
APPL NO 16/987942
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Weapons for Projecting Missiles Without Use of Explosive or Combustible Propellant Charge; Weapons Not Otherwise Provided for
F41B 9/0087 (20130101) Original (OR) Class

Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General
F41H 11/12 (20130101)

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 10/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of State (DOS) 

US 11260995 Bland
FUNDED BY
Department of State (DOS)
National Aeronautics and Space Administration (NASA)
John F. Kennedy Space Center (KSC)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) THE BOEING COMPANY (Chicago, Illinois)
INVENTOR(S) Mitchell C. Bland (Houston, Texas)
ABSTRACT A multi-layer shell structure for a vehicle and method of providing a multi-layer shell structure for a vehicle. The multi-layer structure includes a thermal protection system (TPS) layer, a structural layer connected to the TPS layer, and a high tensile fabric barrier layer bonded to the structural layer. Room-temperature-vulcanizing silicone may be used to bond the TPS layer to the structural layer and bond the high tensile fabric barrier layer to the structural layer. The high tensile fabric barrier layer may create a seal on the structural layer. The multi-layer shell structure may include inner shell enclosing a passenger and/or cargo compartment and an annulus between the inner shell and the high tensile fabric barrier layer. The high tensile fabric barrier layer may prohibit entry of gas into the annulus in the event a hole is created through a portion of the multi-layer shell structure.
FILED Monday, October 29, 2018
APPL NO 16/173821
ART UNIT 1784 — Miscellaneous Articles, Stock Material
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 3/12 (20130101)
B32B 5/024 (20130101)
B32B 5/26 (20130101)
B32B 7/12 (20130101)
B32B 15/00 (20130101)

Aeroplanes; Helicopters
B64C 1/40 (20130101)

Cosmonautics; Vehicles or Equipment Therefor
B64G 1/12 (20130101) Original (OR) Class
B64G 1/14 (20130101)
B64G 1/62 (20130101)

Mining or Quarrying
E21C 51/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 11261315 Hosseinnezhad Mohtarami et al.
FUNDED BY
Department of Transportation (USDOT)
Federal Highway Administration (FHWA)
National Cooperative Highway Research Program (NCHRP)
APPLICANT(S) North Carolina Agricultural and Technical State University (Greensboro, North Carolina)
ASSIGNEE(S) North Carolina Agricultural and Technical State University (Greensboro, North Carolina)
INVENTOR(S) Shahrzad Hosseinnezhad Mohtarami (Greensboro, North Carolina);  SK Faisal Kabir (Greensboro, North Carolina);  Mahour Mellat-Parast (Greensboro, North Carolina);  Elham Fini (Greensboro, North Carolina)
ABSTRACT The presently disclosed subject matter generally relates to environmentally friendly asphalt binder additive.
FILED Thursday, January 09, 2020
APPL NO 16/738817
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/28 (20130101)
C08J 2317/00 (20130101)

Compositions of Macromolecular Compounds
C08L 17/00 (20130101) Original (OR) Class
C08L 23/0853 (20130101)
C08L 95/00 (20130101)
C08L 2555/82 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Reconnaissance Office (NRO) 

US 11264526 Nguyen et al.
FUNDED BY
National Reconnaissance Office (NRO)
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Minh B. Nguyen (Thousand Oaks, California);  Diego Carrasco (Los Angeles, California);  Rajesh D. Rajavel (Oak Park, California)
ABSTRACT A phototransistor includes an emitter, a collector, and a base between the emitter and the collector. The base has a thickness greater than 500 nanometers and the base absorbs photons passing through the collector to the base.
FILED Friday, January 24, 2020
APPL NO 16/752072
ART UNIT 2896 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/184 (20130101)
H01L 31/0304 (20130101)
H01L 31/0368 (20130101)
H01L 31/1105 (20130101) Original (OR) Class
H01L 31/022408 (20130101)
H01L 31/035236 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Office of the Director of National Intelligence (ODNI) 

US 11262785 Monroe et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Security Agency (NSA)
Maryland Procurement Office (MPO)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland)
INVENTOR(S) Christopher Monroe (Ellicott City, Maryland);  Jiehang Zhang (College Park, Maryland);  David Wong-Campos (Hyattsville, Maryland);  Antonios Kyprianidis (Takoma, Maryland);  Patrick Michael Becker (College Park, Maryland)
ABSTRACT The disclosure describes an adaptive and optimal imaging of individual quantum emitters within a lattice or optical field of view for quantum computing. Advanced image processing techniques are described to identify individual optically active quantum bits (qubits) with an imager. Images of individual and optically-resolved quantum emitters fluorescing as a lattice are decomposed and recognized based on fluorescence. Expected spatial distributions of the quantum emitters guides the processing, which uses adaptive fitting of peak distribution functions to determine the number of quantum emitters in real time. These techniques can be used for the loading process, where atoms or ions enter the trap one-by-one, for the identification of solid-state emitters, and for internal state-detection of the quantum emitters, where each emitter can be fluorescent or dark depending on its internal state. This latter application is relevant to efficient and fast detection of optically active qubits in quantum simulations and quantum computing.
FILED Thursday, January 03, 2019
APPL NO 16/239084
ART UNIT 2878 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)
B82Y 40/00 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 1/42 (20130101)
G01J 2001/4247 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6458 (20130101)

Optical Computing Devices;
G06E 3/005 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/66977 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11262301 Hug et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Office (CCDC ARO)
National Aeronautics and Space Administration (NASA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Photon Systems, Inc. (Covina, California)
ASSIGNEE(S) Photon Systems, Inc. (Covina, California)
INVENTOR(S) William F. Hug (Altadena, California);  Rohit Bhartia (Pasadena, California);  Ray D. Reid (Glendora, California);  Arthur L. Lane (Arcadia, California)
ABSTRACT Naphthalene, benzene, toluene, xylene, and other volatile organic compounds VOCs have been identified as serious health hazards. Embodiments of the invention are directed to methods and apparatus for near-real-time in-situ detection and accumulated dose measurement of exposure to naphthalene vapor and other hazardous gaseous VOCs. The methods and apparatus employ excitation of fluorophors native or endogenous to compounds of interest using light sources emitting in the ultraviolet below 300 nm and measurement of native fluorescence emissions in distinct wavebands above the excitation wavelength. The apparatus of some embodiments are cell-phone-sized sensor/dosimeter “badges” to be worn by personnel potentially exposed to hazardous VOCs. The badge sensor of some embodiments provides both real time detection and data logging of exposure to naphthalene or other VOCs of interest from which both instantaneous and accumulated dose can be determined.
FILED Friday, September 04, 2020
APPL NO 17/013469
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/10 (20130101)
G01J 3/36 (20130101)
G01J 3/44 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/64 (20130101) Original (OR) Class
G01N 21/65 (20130101)
G01N 21/6486 (20130101)
G01N 21/8806 (20130101)
G01N 27/44721 (20130101)
G01N 33/0047 (20130101)
G01N 2021/6421 (20130101)
G01N 2021/6471 (20130101)
G01N 2201/062 (20130101)
G01N 2201/126 (20130101)
G01N 2201/0612 (20130101)
G01N 2201/06113 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 11261560 Chudnovsky et al.
FUNDED BY
U.S. State Government
State of California
California Energy Commission (CEC)
APPLICANT(S) UTILIZATION TECHNOLOGY DEVELOPMENT, NFP (Des Plaines, Illinois)
ASSIGNEE(S) UTILIZATION TECHNOLOGY DEVELOPMENT, NFP (Des Plaines, Illinois)
INVENTOR(S) Yaroslav Chudnovsky (Skokie, Illinois);  Dmytro Buyadgie (Pleasant Hill, California);  Olexiy Buyadgie (Walnut Creek, California)
ABSTRACT Methods and systems for the thermo-vacuum drying and processing of objects such as clothes. A vacuum ejector driven by high-pressure steam is employed to evacuate evaporated moisture mixed with air from a dryer vessel producing an intensification of the drying process such as can significantly reduce the energy and time requirements for the drying process and increase water utilization.
FILED Friday, December 27, 2019
APPL NO 16/728793
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Laundering, Drying, Ironing, Pressing or Folding Textile Articles
D06F 58/10 (20130101)
D06F 58/24 (20130101)
D06F 58/26 (20130101)
D06F 58/30 (20200201)
D06F 58/206 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 11264960 Bagga et al.
FUNDED BY
APPLICANT(S) Sunny Bagga (Corona, California);  Brian J. Cadwell (Pasadena, Maryland);  Shaun Mark Goodwin (East New Market, Maryland);  Scott F. Allwine (Leesburg, Virginia)
ASSIGNEE(S) NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S) Sunny Bagga (Corona, California);  Brian J. Cadwell (Pasadena, Maryland);  Shaun Mark Goodwin (East New Market, Maryland);  Scott F. Allwine (Leesburg, Virginia)
ABSTRACT A current source circuit can include a first amplifier circuit and a second amplifier circuit. Each of the first and second amplifier circuits can be configured to generate respective amplifier output voltages based on a corresponding input voltage and respective feedback voltage. The current source circuit can further include a cross-coupling circuit that can include a first set of resistors and a second set of resistors. The first set of resistors can be configured to establish a first cross-coupling voltage based on the first amplifier output voltage and the second set of resistors can be configured to establish a second cross-coupling voltage based on the second amplifier output voltage. The first and second amplifier circuits can be configured to maintain the first and second cross-coupling voltage at a given voltage amplitude to provide a constant current at an output node of the current source circuit.
FILED Monday, April 13, 2020
APPL NO 16/847017
ART UNIT 2843 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/28 (20130101)

Amplifiers
H03F 3/45076 (20130101) Original (OR) Class
H03F 2200/372 (20130101)
H03F 2203/45101 (20130101)
H03F 2203/45134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, March 01, 2022.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/details-patents-20220301.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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