FedInvent™ Patents
Patent Details for Tuesday, March 08, 2022
This page was updated on Wednesday, March 09, 2022 at 09:01 AM GMT
Department of Health and Human Services (HHS)
| US 11266129 | Newman et al. |
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| FUNDED BY |
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| APPLICANT(S) | VERSITI BLOOD RESEARCH INSTITUTE FOUNDATION, INC. (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peter J. Newman (Bayside, Wisconsin); Huiying Zhi (Brookfield, Wisconsin) |
| ABSTRACT | A transgenic mouse comprising T30A, S32P, Q33L, N39D, and M470Q mutations in GPIIIa, as well as methods for making the transgenic mouse and methods for using the transgenic mouse to screen test compounds are described. |
| FILED | Tuesday, November 05, 2019 |
| APPL NO | 16/674804 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) Original (OR) Class A01K 2217/07 (20130101) A01K 2227/105 (20130101) A01K 2267/0387 (20130101) Peptides C07K 14/70546 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/89 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/577 (20130101) G01N 33/5047 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266315 | Xia et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Amherst, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Amherst, New York) |
| INVENTOR(S) | Jun Xia (Amherst, New York); Yuehang Wang (Buffalo, New York) |
| ABSTRACT | Devices and methods for photoacoustic tomography are disclosed herein. One exemplary photoacoustic tomography device uses a laser to produce acoustic waves in a sample. A transducer receives the acoustic waves through a slit formed by one or more blades positioned substantially parallel to the receiving aperture of the transducer. An acoustic absorber is affixed to each of the one or more blades along a surface proximal to the transducer. A processor acquires acoustic data and reconstructs photoacoustic tomographic images based on the acquired data. Reconstructing the image involves setting reconstruction parameters, defining a reconstruction area, reconstruction position, and pixel size, and calculating an acoustic travelling path for the sample to each transducer element. The acoustic travelling paths are saved into a three-dimensional array. |
| FILED | Monday, December 05, 2016 |
| APPL NO | 15/781329 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0073 (20130101) A61B 5/0095 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/1702 (20130101) G01N 29/24 (20130101) G01N 29/2418 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 23/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266324 | Polimeni et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Jonathan Polimeni (Cambridge, Massachusetts); Andre Van Der Kouwe (Woburn, Massachusetts); Matthew Tisdall (Somerville, Massachusetts); Bruce Fischl (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods for performing fast multi-contrast magnetic resonance imaging (“MRI”) are provided. In general, data are acquired from both multiple echo times (“TEs”) and at multiple effective inversion times (“TIs”). Following the application of a magnetization preparation radio frequency (“RF”) pulse, a plurality of different multi-echo acquisitions are performed, thereby acquiring data from multiple different TEs during different portions of the longitudinal magnetization recovery curve. Data acquisition in these inner encoding loops (i.e., during each multi-echo acquisition) can be accelerated to efficiently provide for the acquisition of multiple contrasts in the time normally required to acquire a single contrast. |
| FILED | Friday, April 24, 2015 |
| APPL NO | 15/305515 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/58 (20130101) G01R 33/5602 (20130101) G01R 33/5611 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266339 | Kaplan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Lee W. Tien (Brookline, Massachusetts); Gary G. Leisk (Wilmington, Massachusetts); Tim Jia-Ching Lo (Lungtan, Taiwan); Cinzia Metallo (Somerville, Massachusetts); Fiorenzo Omenetto (Wakefield, Massachusetts) |
| ABSTRACT | Provided herein relates to implantable devices and systems with dynamic silk coatings. In some embodiments, the dynamic silk coatings can be formed in situ or in vivo. |
| FILED | Thursday, May 09, 2019 |
| APPL NO | 16/408122 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/291 (20210101) Original (OR) Class A61B 5/686 (20130101) A61B 5/4088 (20130101) A61B 5/4094 (20130101) A61B 5/6868 (20130101) A61B 5/6877 (20130101) A61B 2562/125 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/227 (20130101) A61L 27/3604 (20130101) A61L 27/3675 (20130101) A61L 31/10 (20130101) A61L 31/14 (20130101) A61L 31/16 (20130101) A61L 31/047 (20130101) A61L 2400/18 (20130101) A61L 2420/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/0529 (20130101) A61N 1/0541 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266342 | Huggins et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Jane E. Huggins (Fenton, Michigan); Seth Warschausky (Ann Arbor, Michigan); Ramses Eduardo Alcaide (Ann Arbor, Michigan) |
| ABSTRACT | Methods, systems, apparatus, and non-transitory computer readable media are disclosed utilizing brain-computer interfaces (BCIs). Various embodiments are disclosed to allow a user to directly select multiple-choice answers, to provide motorized wheelchair controls, and to allow a user to play a game via the BCI. When used in a cognitive assessment test, embodiments include the administration of unmodified standardized tests with results in the same or a similar format as those taken without a BCI. Various embodiments are disclosed to improve the accuracy of BCI test administration using a three-step process for each test question, which includes determining whether the user intends to select an answer, monitoring user brain activity to determine a selected answer, and verifying the selected answer. In addition, the selected answer may be verified by monitoring user brain activity in accordance with a hold-release process to determine whether a user intends to initiate a state change. |
| FILED | Friday, May 22, 2015 |
| APPL NO | 15/305030 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/316 (20210101) A61B 5/374 (20210101) A61B 5/378 (20210101) A61B 5/742 (20130101) A61B 5/4088 (20130101) Original (OR) Class A61B 5/7221 (20130101) A61B 5/7264 (20130101) A61B 5/7267 (20130101) A61B 5/7282 (20130101) A61B 5/7435 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/72 (20130101) A61F 4/00 (20130101) Electric Digital Data Processing G06F 3/015 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 7/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266363 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Ge Wang (Loudonville, New York); Wenxiang Cong (Albany, New York) |
| ABSTRACT | Systems and methods for obtaining scattering images during computed tomography (CT) imaging are provided. Two gratings or grating layers can be disposed between the object to be imaged and the detector, and the gratings or grating layers can be arranged such that primary X-rays are blocked while scattered X-rays that are deflected as they pass through the object to be imaged reach the detector to generate the scattering image. |
| FILED | Friday, February 17, 2017 |
| APPL NO | 15/999466 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/03 (20130101) A61B 6/032 (20130101) A61B 6/0407 (20130101) A61B 6/483 (20130101) A61B 6/484 (20130101) A61B 6/508 (20130101) A61B 6/4291 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266599 | Belinsky et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lovelace Biomedical Research Institute (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Lovelace Biomedical Research Institute (Albuquerque, New Mexico) |
| INVENTOR(S) | Steven A. Belinsky (Albuquerque, New Mexico); Philip J. Kuehl (Albuquerque, New Mexico); Aaron Badenoch (Bend, Oregon); Michael Burke (Bend, Oregon); Devon Dubose (Bend, Oregon) |
| ABSTRACT | An embodiment of the present invention provides for a dry powder pharmaceutical composition suitable for dispersion in an aerosol for inhaled administration to a patient with cancer, the composition comprising: a cytidine analogue including salts, solvates, hydrates, and esters thereof; and a pharmaceutically acceptable excipient together forming the dry powder pharmaceutical composition suitable for dispersion in the aerosol for administration via inhalation to the patient with cancer. Another embodiment provides for a method of making the composition and a further embodiment provides for a method a treating a patient in need thereof with the composition. |
| FILED | Friday, August 07, 2020 |
| APPL NO | 16/988312 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/12 (20130101) A61K 9/0075 (20130101) Original (OR) Class A61K 31/7068 (20130101) A61K 47/10 (20130101) A61K 47/26 (20130101) A61K 47/183 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266602 | Fox et al. |
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| FUNDED BY |
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| APPLICANT(S) | Infectious Disease Research Institute (Seattle, Washington); University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | INFECTIOUS DISEASE RESEARCH INSTITUTE (Seattle, Washington) |
| INVENTOR(S) | Christopher B. Fox (Sumner, Washington); Susan S. Lin (Seattle, Washington); Darrick Carter (Seattle, Washington); Neal Van Hoeven (Seattle, Washington); Mayuresh M. Abhyankar (Charlottesville, Virginia); William A. Petri (Charlottesville, Virginia) |
| ABSTRACT | Provided herein are PEGylated liposomes, and methods of making and using thereof. The PEGylated liposomes comprise at least a cholesterol, a non-PEGylated neutral lipid, and a PEGylated lipid, wherein the average molecular weight of the PEG component in the PEGylated lipid is about 5000 Daltons or less. The PEGylated liposomes are stable and capable of delivery of an agent for the generation of an immune response, for example an agent for vaccine, therapeutic, or diagnostic uses. Compositions and methods related to making the PEGylated liposomes and using the PEGylated liposomes for stimulating an immune response are also provided. |
| FILED | Monday, May 15, 2017 |
| APPL NO | 16/098619 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) Original (OR) Class A61K 31/739 (20130101) A61K 39/39 (20130101) A61K 2039/6087 (20130101) A61K 2039/55555 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266606 | Vegas et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Arturo J. Vegas (Belmont, Massachusetts); Joshua C. Doloff (Quincy, Massachusetts); Omid Veiseh (Bellaire, Texas); Minglin Ma (Ithaca, New York); Robert S. Langer (Newton, Massachusetts); Daniel G. Anderson (Framingham, Massachusetts) |
| ABSTRACT | Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates are useful as a matrix for coating of any material where reduced fibrosis is desired, such as encapsulated cells for transplantation and medical devices implanted or used in the body. |
| FILED | Thursday, September 26, 2019 |
| APPL NO | 16/584170 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 9/5036 (20130101) Original (OR) Class A61K 35/39 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/085 (20130101) A61L 29/085 (20130101) A61L 31/10 (20130101) A61L 31/10 (20130101) A61L 33/08 (20130101) A61L 33/08 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0084 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) C08L 5/04 (20130101) C08L 5/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0012 (20130101) C12N 5/0677 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266610 | Harrelson et al. |
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| FUNDED BY |
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| APPLICANT(S) | PACIFIC UNIVERSITY (Forest Grove, Oregon) |
| ASSIGNEE(S) | PACIFIC UNIVERSITY (Forest Grove, Oregon) |
| INVENTOR(S) | John P. Harrelson (Forest Grove, Oregon); Deepa A. Rao (Beaverton, Oregon) |
| ABSTRACT | Compounds, compositions, and methods of use of such compounds and compositions are provided for reducing human dependency to nicotine. In one example, a method of treating an individual with an addiction to nicotine comprises administering to the individual a compound that is a structural analog of trans-cinnamaldehyde ((2E)-3-Phenylprop-2-enal): Based on the administration, a rate at which nicotine is metabolized may be reduced, which in turn may reduce a desire for the individual to consume nicotine-containing products. |
| FILED | Thursday, October 24, 2019 |
| APPL NO | 16/663291 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/11 (20130101) Original (OR) Class A61K 31/465 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/34 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266616 | Kern et al. |
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| FUNDED BY |
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| APPLICANT(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| ASSIGNEE(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| INVENTOR(S) | Dorothee Kern (Waltham, Massachusetts); Adelajda Zorba (Waltham, Massachusetts) |
| ABSTRACT | The present invention features therapeutic compositions comprising an agent that specifically binds to a PIF pocket of Aurora A kinase and an agent that specifically binds to an ATP-binding site of Aurora A kinase, and the use of the therapeutic compositions to modulate Aurora A kinase for the treatment of cancer. |
| FILED | Wednesday, February 08, 2017 |
| APPL NO | 16/075550 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/192 (20130101) Original (OR) Class A61K 31/192 (20130101) A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/517 (20130101) A61K 31/517 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/40 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2500/04 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/00 (20190201) G16B 15/30 (20190201) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/50 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266617 | Yilmaz et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Omer Yilmaz (Cambridge, Massachusetts); Chia-Wei Cheng (Cambridge, Massachusetts); George Eng (Boston, Massachusetts); Fang Wang (Cambridge, Massachusetts) |
| ABSTRACT | The present invention provides compositions comprising β-hydroxybutyrate, cyclic or linear β-hydroxybutyrate oligomers, and/or β-hydroxybutyrate ester derivatives, or pharmaceutically-acceptable salts thereof. In various embodiments, the compositions are encapsulated by nanoparticles, such as nanoparticles comprising, e.g., poly(lactic-co-glycolic acid). In additional embodiments, the invention provides methods of using such compositions to induce intestinal stem cell regeneration and/or treat radiation-induced intestinal damage in a subject. |
| FILED | Wednesday, October 16, 2019 |
| APPL NO | 16/655125 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1647 (20130101) A61K 9/5153 (20130101) A61K 31/194 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266618 | Rahbar et al. |
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| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
| INVENTOR(S) | Samuel Rahbar (Beverly Hills, California); Timothy W. Synold (Monrovia, California); John Termini (Altadena, California); Daniel Tamae (Duarte, California); Gerald Wuenschell (Duarte, California) |
| ABSTRACT | Methods of quantifying N2-carboxyethyl-2′-deoxyguanosine (CEdG) levels in biological samples and comparing those levels to known normal levels can diagnose a number of disorders, including diabetes and cancer. Methods can also determine whether therapies for disorders are effective by measuring CEdG levels before and after treatment. Measurement of CEdG levels occurs using liquid chromatography electrospray ionization tandem mass spectrometry. |
| FILED | Friday, December 29, 2017 |
| APPL NO | 15/859188 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/195 (20130101) Original (OR) Class A61K 45/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/7233 (20130101) G01N 30/7266 (20130101) G01N 2030/045 (20130101) G01N 2030/8827 (20130101) G01N 2030/8868 (20130101) G01N 2800/042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266624 | Gao |
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| FUNDED BY |
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| APPLICANT(S) | Texas Tech University System (Lubbock, Texas) |
| ASSIGNEE(S) | Texas Tech University System (Lubbock, Texas) |
| INVENTOR(S) | Weimin Gao (Lubbock, Texas) |
| ABSTRACT | The present invention includes a method and compositions for preventing primary or acquired resistance of epidermal growth factor receptors (EGFR) inhibitors in a cancer with deregulated EGFR comprising: identifying a subject suspected of needing treatment for primary or acquired resistance to epidermal growth factor receptor (EGFR) inhibitors of the cancer with deregulated EGFR; and providing the subject with a therapeutically effective amount of a chromosome region maintenance 1 (CRM1) inhibitor and an inhibitor of EGFR in an amount sufficient to reduce or eliminate the cancer. |
| FILED | Wednesday, April 03, 2019 |
| APPL NO | 16/374026 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/366 (20130101) Original (OR) Class A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/519 (20130101) A61K 31/4196 (20130101) A61K 31/4245 (20130101) A61K 31/4412 (20130101) A61K 31/4439 (20130101) A61K 31/5377 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266626 | Schon et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Eric A. Schon (Bronx, New York); Estela Area-Gomez (New York, New York) |
| ABSTRACT | The invention provides for methods for treating Alzheimer's Disease in a subject by reducing ER-MAM localized APP-C99. |
| FILED | Friday, March 09, 2018 |
| APPL NO | 15/917344 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/11 (20130101) A61K 31/37 (20130101) A61K 31/40 (20130101) A61K 31/55 (20130101) A61K 31/137 (20130101) A61K 31/166 (20130101) A61K 31/192 (20130101) A61K 31/197 (20130101) A61K 31/327 (20130101) A61K 31/366 (20130101) A61K 31/397 (20130101) Original (OR) Class A61K 31/513 (20130101) A61K 31/519 (20130101) A61K 31/519 (20130101) A61K 31/566 (20130101) A61K 31/675 (20130101) A61K 31/4188 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266642 | Tomer et al. |
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| FUNDED BY |
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| APPLICANT(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| ASSIGNEE(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| INVENTOR(S) | Yaron Tomer (New York, New York); Roman Osman (New York, New York) |
| ABSTRACT | A method for treating autoimmune thyroid disease is disclosed. The method comprises administering a molecule of molecular weight below 700 that inhibits the binding of the nonadecapeptide IPDNLFLKSDGRIKYTLNK (SEQ ID NO:1) to HLA-DRβ1-Arg74. Such compounds are found in the class of bisbenzylisoquinoline alkaloids represented by formula I |
| FILED | Tuesday, December 20, 2016 |
| APPL NO | 16/063942 |
| ART UNIT | 1699 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4725 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266647 | Stewart et al. |
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| FUNDED BY |
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| APPLICANT(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| ASSIGNEE(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| INVENTOR(S) | Andrew F. Stewart (New York, New York); Peng Wang (Fresh Meadows, New York) |
| ABSTRACT | The present invention relates to a method of increasing cell proliferation in a population of pancreatic beta cells and a method of treating a subject for a condition associated with an insufficient level of insulin secretion. Also disclosed is a composition. The composition includes a dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1 A) inhibitor and a transforming growth factor beta (TGFP) superfamily signaling pathway inhibitor. |
| FILED | Thursday, October 26, 2017 |
| APPL NO | 16/344230 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/428 (20130101) A61K 31/437 (20130101) A61K 31/437 (20130101) A61K 31/454 (20130101) A61K 31/519 (20130101) Original (OR) Class A61K 31/4045 (20130101) A61K 31/4709 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/18 (20180101) A61P 3/10 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0676 (20130101) C12N 2501/999 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266676 | Hughes-Fulford |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA as represented by THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (, None); The United States Government as represented by the Department of Veterans Affairs (, None) |
| INVENTOR(S) | Millie Hughes-Fulford (San Francisco, California) |
| ABSTRACT | Disclosed herein are methods for treating an immune system condition and/or altering T cell activation in a subject. Also disclosed herein are methods for diagnosing an immune system condition in a subject. In some examples, the methods can include measuring expression of at least one T cell activation-related miRNA in a sample obtained from a subject. The methods further include administering to the subject a therapeutically effective amount of an miRNA or mimic thereof, and/or an inhibitor of miRNA or mimic thereof and/or administering to the subject T cells contacted with an effective amount of miRNA or mimic thereof, and/or an inhibitor of miRNA or mimic thereof. |
| FILED | Friday, October 27, 2017 |
| APPL NO | 16/345512 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/141 (20130101) C12N 2330/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) C12Q 1/6883 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266689 | Metelitsa et al. |
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| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas) |
| INVENTOR(S) | Leonid S. Metelitsa (Sugar Land, Texas); Amy N. Courtney (Houston, Texas); Gengwen Tian (Houston, Texas) |
| ABSTRACT | Embodiments of the disclosure include methods and compositions for producing NKT cells effective for immunotherapy and also methods and compositions for providing an effective amount of NKT cells to an individual in need of immunotherapy. In specific embodiments, the NKT cells are CD62L+ and have been exposed to one or more costimulatory agents to maintain CD62L expression. The NKT cells may be modified to incorporate a chimeric antigen receptor, in some cases. |
| FILED | Monday, June 03, 2019 |
| APPL NO | 16/429581 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/178 (20130101) A61K 39/0011 (20130101) A61K 2035/124 (20130101) A61K 2039/5156 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 37/00 (20180101) Peptides C07K 16/2803 (20130101) C07K 16/3084 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/10 (20130101) C12N 5/0646 (20130101) C12N 2501/599 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266692 | Moriarity et al. |
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| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); Intima Bioscience, Inc. (New York, New York); The U.S.A., as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); Intima Bioscience, Inc. (New York, New York); The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Branden Moriarity (Shoreview, Minnesota); Beau Webber (Coon Rapids, Minnesota); Modassir Choudhry (New York, New York); Steven A. Rosenberg (Potomac, Maryland); Douglas C. Palmer (North Bethesda, Maryland); Nicholas P. Restifo (Chevy Chase, Maryland) |
| ABSTRACT | Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating cancer. |
| FILED | Friday, June 12, 2020 |
| APPL NO | 16/900372 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Peptides C07K 14/4718 (20130101) C07K 14/7051 (20130101) C07K 14/7158 (20130101) C07K 14/70503 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 9/22 (20130101) C12N 9/96 (20130101) C12N 15/87 (20130101) C12N 15/113 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266712 | Jaynes et al. |
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| FUNDED BY |
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| APPLICANT(S) | Riptide Bioscience, Inc. (Vallejo, California) |
| ASSIGNEE(S) | Riptide Bioscience, Inc. (Vallejo, California) |
| INVENTOR(S) | Jesse M. Jaynes (Auburn, Alabama); L. Edward Clemens (Bainbridge Island, Washington); Henry Wilfred Lopez (Napa, California); George R. Martin (Rockville, California); Kathryn Woodburn (Saratoga, California) |
| ABSTRACT | Aspects of the present invention relate to peptides having antimicrobial activity. In certain aspects, the invention relates to peptides having potent antimicrobial activity, broad-spectrum antimicrobial activity, and/or the ability to kill otherwise antibiotic-resistant microbes, or microbes protected by biofilms. |
| FILED | Friday, January 24, 2020 |
| APPL NO | 16/752037 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0053 (20130101) A61K 9/0073 (20130101) A61K 38/10 (20130101) Original (OR) Class A61K 38/16 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) A61P 31/10 (20180101) Peptides C07K 7/08 (20130101) C07K 14/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266713 | Pei et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Dehua Pei (Columbus, Ohio); Ziqing Qian (Columbus, Ohio) |
| ABSTRACT | Disclosed is a general, reversible bicyclization strategy to increase both the proteolytic stability and cell permeability of peptidyl drugs. A peptide drug is fused with a short cell-penetrating motif and converted into a conformationally constrained bicyclic structure through the formation of a pair of disulfide bonds. The resulting bicyclic peptide has greatly enhanced proteolytic stability as well as cell-permeability. Once inside the cell, the disulfide bonds are reduced to produce a linear, biologically active peptide. This strategy was applied to generate a cell-permeable bicyclic peptidyl inhibitor against the NEMO-IKK interaction. |
| FILED | Thursday, November 09, 2017 |
| APPL NO | 16/348706 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/12 (20130101) Original (OR) Class Peptides C07K 5/10 (20130101) C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 7/50 (20130101) C07K 14/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266716 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (Manhasset, New York) |
| ASSIGNEE(S) | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (Manhasset, New York) |
| INVENTOR(S) | Ping Wang (Roslyn, New York); Haichao Wang (Edison, New Jersey) |
| ABSTRACT | A method of treating a sterile inflammatory condition in a subject using an isolated dermcidin peptide or an active fragment thereof of or an active analog thereof is provided. Also provided is a method of inhibiting organ transplantation-associated is chemia/reperfusion and/or organ transplantation-associated inflammation. |
| FILED | Friday, October 21, 2016 |
| APPL NO | 15/769880 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0215 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 38/16 (20130101) A61K 38/1729 (20130101) Original (OR) Class A61K 47/60 (20170801) A61K 47/549 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266726 | Wood et al. |
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| FUNDED BY |
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| APPLICANT(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Baylor College of Medicine (Houston, Texas) |
| INVENTOR(S) | Lauren V. Wood (Bethesda, Maryland); Brenda D. Roberson (Frederick, Maryland); Jay A. Berzofsky (Bethesda, Maryland); John C. Morris (Cincinnati, Ohio); Jason C. Steel (Queensland, Australia); Masaki Terabe (Potomac, Maryland); Malcolm K. Brenner (Houston, Texas) |
| ABSTRACT | Recombinant adenoviruses expressing the extracellular (EC) and transmembrane (TM) domains of human HER2 (HER2ECTM) are described. The recombinant adenoviruses express a chimeric fiber protein having the adenovirus type 35 (Ad5) shaft and knob domains, which facilitates transduction of human dendritic cells by the recombinant HER2ECTM expressing adenovirus. Compositions that include dendritic cells transduced by the recombinant adenovirus and their use for treating HER-positive tumors is described. |
| FILED | Monday, October 31, 2016 |
| APPL NO | 15/771932 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 39/001106 (20180801) A61K 2039/5154 (20130101) A61K 2039/5256 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266732 | Picker et al. |
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| FUNDED BY |
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| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Louis Picker (Portland, Oregon); Jay A. Nelson (Lake Oswego, Oregon); Klaus Frueh (Portland, Oregon); Michael A. Jarvis (Portland, Oregon); Scott G. Hansen (Portland, Oregon) |
| ABSTRACT | The present disclosure relates to recombinant rhesus cytomegalovirus (RhCMV) and human cytomegalovirus (HCMV) vectors encoding heterologous antigens, such as pathogen-specific antigens or tumor antigens, which may be used, for example, for the treatment or prevention of infectious disease or cancer. The recombinant RhCMV or HCMV vectors elicit and maintain high level cellular immune responses specific for the heterologous antigen while including deletions in one or more genes essential or augmenting for CMV replication, dissemination or spread. |
| FILED | Friday, April 27, 2018 |
| APPL NO | 15/965246 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/08 (20130101) A61K 39/0011 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 39/13 (20130101) A61K 39/21 (20130101) A61K 39/145 (20130101) A61K 39/275 (20130101) A61K 2039/58 (20130101) A61K 2039/552 (20130101) A61K 2039/572 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/005 (20130101) C07K 14/16 (20130101) C07K 14/045 (20130101) C07K 14/161 (20130101) C07K 14/162 (20130101) C07K 14/163 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 15/869 (20130101) C12N 2710/16111 (20130101) C12N 2710/16134 (20130101) C12N 2710/16141 (20130101) C12N 2710/16143 (20130101) C12N 2710/16162 (20130101) C12N 2710/16171 (20130101) C12N 2710/24134 (20130101) C12N 2730/10134 (20130101) C12N 2740/15022 (20130101) C12N 2740/15034 (20130101) C12N 2740/16034 (20130101) C12N 2760/14134 (20130101) C12N 2760/16134 (20130101) C12N 2770/32634 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266734 | Palese et al. |
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| FUNDED BY |
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| APPLICANT(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| ASSIGNEE(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| INVENTOR(S) | Peter Palese (New York, New York); Adolfo Garcia-Sastre (New York, New York); Megan Ermler (New York, New York); Florian Krammer (New York, New York) |
| ABSTRACT | Provided herein are chimeric hemagglutinin (HA) polypeptides and uses thereof for inducing an immune response (e.g., an antibody response) against influenza virus. Also provided herein are methods of generating antibodies to the chimeric HA polypeptides in a subject. |
| FILED | Wednesday, June 14, 2017 |
| APPL NO | 16/305845 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/70 (20130101) A61K 2039/525 (20130101) A61K 2039/545 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/16122 (20130101) C12N 2760/16134 (20130101) C12N 2760/16171 (20130101) C12N 2760/16222 (20130101) C12N 2760/16234 (20130101) C12N 2760/16271 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266743 | Wimley et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Administrators of the Tulane Educational Fund (New Orleans, Louisiana) |
| ASSIGNEE(S) | The Administrators of the Tulane Educational Fund (New Orleans, Louisiana) |
| INVENTOR(S) | William Charles Wimley (New Orleans, Louisiana); Charles Gannon Starr (New Orleans, Louisiana); William Berkeley Kauffman (New Orleans, Louisiana) |
| ABSTRACT | Described herein are membrane permeabilizing peptides and antimicrobial peptides, polynucleotides encoding the peptides, and compositions containing the peptides. Furthermore, described herein are methods for using the peptides, polynucleotides, and compositions for research, diagnosis, and therapy. |
| FILED | Thursday, October 25, 2018 |
| APPL NO | 16/758791 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/64 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) A61P 35/00 (20180101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 2310/313 (20130101) C12N 2310/315 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266746 | Oppenheim et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United Slates of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Joost J. Oppenheim (Rockville, Maryland); De Yang (Frederick, Maryland); Zhen Han (Frederick, Maryland); Joseph John Barchi, Jr. (Frederick, Maryland); Michael Bustin (Rockville, Maryland) |
| ABSTRACT | Methods of treating cancer or reducing the incidence of relapse of a cancer in a subject comprising co-administration of Toll-like receptor (TLR) 4 ligand, such as an HMGN1 protein, and a TLR 7 or 8 ligand, and optionally an immune checkpoint inhibitor, to the subject in need of such therapy. The TLR4-mediated immune-stimulating effect is synergistically enhanced by ligands of TLR7 or 8, and the immune checkpoint inhibitor. Also described here is a nanoparticle delivery platform for the co-administration of the TLR 4 ligand and the TLR 7 or 8 ligand. |
| FILED | Friday, February 24, 2017 |
| APPL NO | 16/313454 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/51 (20130101) A61K 9/5115 (20130101) A61K 31/664 (20130101) A61K 31/4745 (20130101) A61K 31/4745 (20130101) A61K 38/1709 (20130101) A61K 38/1709 (20130101) A61K 39/39558 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 47/02 (20130101) A61K 47/6923 (20170801) A61K 47/6929 (20170801) Original (OR) Class A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 16/2818 (20130101) C07K 16/2827 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266766 | Bhatia et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Sangeeta N. Bhatia (Lexington, Massachusetts); Kelly R. Stevens (Seattle, Washington); Christopher S. Chen (Newton, Massachusetts) |
| ABSTRACT | Engineered human tissue seed constructs are provided that are suitable for implantation in subjects. Methods of making and using the engineered tissue seed constructs are provided. |
| FILED | Friday, March 26, 2021 |
| APPL NO | 17/213436 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/52 (20130101) Original (OR) Class A61L 27/225 (20130101) A61L 27/3804 (20130101) A61L 27/3808 (20130101) A61L 27/3886 (20130101) A61L 27/3891 (20130101) A61L 2430/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266768 | Grinstaff et al. |
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| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Mark Grinstaff (Brookline, Massachusetts); Jonah Andrew Kaplan (Newton, Massachusetts); Julia Wang (Forest Hills, New York) |
| ABSTRACT | The disclosure provides a drug delivery device that can release a drug or other molecule of interest in response to application of a mechanical force, such as tension, and methods of use thereof. The present disclosure provides a tension-responsive drug delivery device by exploiting a difference in mechanical properties between a drug-loaded core material and a supertiydrophobic barrier coating consisting of interconnected micro- and nano-sized particles formulated via the electrospraying of a mixture of biocompatible polymers. |
| FILED | Wednesday, November 26, 2014 |
| APPL NO | 15/039136 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5031 (20130101) A61K 9/5146 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/34 (20130101) A61L 27/50 (20130101) A61L 27/54 (20130101) A61L 29/14 (20130101) A61L 29/16 (20130101) A61L 29/085 (20130101) A61L 31/10 (20130101) A61L 31/14 (20130101) Original (OR) Class A61L 31/16 (20130101) A61L 2400/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267809 | Chory et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Emma J. Chory (Menlo Park, California); Gerald R. Crabtree (Woodside, California); Emily C. Dykhuizen (West Lafayette, Indiana) |
| ABSTRACT | The invention provided here creates a new paradigm for the treatment of a variety of conditions where modulation of a BAF complex is desired. The disclosure that follows outlines a strategy for modulating a BAF complex in a cell, and provides effective compounds, pharmaceutical compositions, development strategies, and treatment protocols, and describes many of the ensuing benefits. A new family of BAF complex modulating compounds has been developed based on a new chemical scaffold including a 12-membered macrolactam core structures. Contacting target cells in vitro or in vivo with the compounds and compositions of this invention can selectively inhibit the activity of BAF complexes in such cells. Some of the BAF complex modulating compounds in this family are particularly effective agents for treating cancer in conjunction with a ATR inhibitor. |
| FILED | Thursday, September 13, 2018 |
| APPL NO | 16/635542 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 273/02 (20130101) C07D 413/10 (20130101) C07D 413/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267816 | Chiosis et al. |
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| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan-Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan-Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Gabriela Chiosis (New York, New York); Pengrong Yan (New York, New York); Pallav Patel (Fresh Meadows, New York); Hardik J. Patel (Kew Gardens, New York); Tony Taldone (Forest Hills, New York); Chenghua Yang (Shanghai, China PRC); Weilin Sun (Princeton, New Jersey); Stefan O. Ochiana (Chevy Chase, Maryland) |
| ABSTRACT | The disclosure relates to novel selective Grp94 inhibitors, compositions comprising an effective amount of such compounds, and methods to treat or prevent a condition, such as cancer, comprising administering to an animal in need thereof an effective amount of such compounds. |
| FILED | Friday, April 05, 2019 |
| APPL NO | 16/376614 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 473/34 (20130101) Original (OR) Class C07D 519/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 35/00 (20190201) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/60 (20190201) G16C 20/64 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267817 | Salvino et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Joseph M. Salvino (Chester Springs, Pennsylvania); Xin Feng (ChongQing, China PRC); Alessandro Fatatis (Penn Valley, Pennsylvania); Fei Shen (Philadelphia, Pennsylvania); Olimpia Meucci (Penn Valley, Pennsylvania) |
| ABSTRACT | The disclosure provides compounds of formula (I) having the structure: Compounds of formula (I) are fractalkine receptor agonists and useful in treating, preventing or minimizing metastasis in a subject diagnosed with cancer. The compounds of the invention are further useful in treating central nervous system diseases (such as, but not limited to, HIV Associated Neurocognitive Disorders (HAND), and/or Alzheimer's disease), pain, inflammation (such as, but not limited to, arthritis), cardiovascular disease (such as, but not limited to, undesired vascular smooth muscle proliferation, atherosclerosis, coronary vascular endothelial dysfunction, and/or coronary artery disease), and/or multiple sclerosis. |
| FILED | Tuesday, May 01, 2018 |
| APPL NO | 16/610450 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/704 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267822 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Shaomeng Wang (Superior Township, Michigan); Weiguo Xiang (Ypsilanti, Michigan); Fuming Xu (Ann Arbor, Michigan); Longchuan Bai (Ann Arbor, Michigan); Ester Fernandez-Salas (Ann Arbor, Michigan); Donna McEachern (Ann Arbor, Michigan) |
| ABSTRACT | The present disclosure provides compounds represented by Formula (I): Formula (I) and the pharmaceutically acceptable salts and solvates thereof, wherein R1, R2a, R2b, R3a, R3b, R4, Y, ═, Ar, W, L, and B are as defined as set forth in the specification. The present disclosure also provides compounds of Formula (I)I for use to treat a condition or disorder responsive to inhibition and/or degradation of BET bromodomains such as cancer. |
| FILED | Wednesday, September 12, 2018 |
| APPL NO | 16/645953 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 495/14 (20130101) C07D 498/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267826 | Burns et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VenatoRx Pharmaceuticals, Inc. (Malvern, Pennsylvania) |
| ASSIGNEE(S) | VENATORX PHARMACEUTICALS, INC. (Malvern, Pennsylvania) |
| INVENTOR(S) | Christopher J. Burns (Malvern, Pennsylvania); Denis Daigle (Street, Maryland); Guo-Hua Chu (Exton, Pennsylvania); Randy W. Jackson (Livingston, Montana); Jodie Hamrick (New Holland, Pennsylvania); Matthew Lucas (Malvern, Pennsylvania); Steven A. Boyd (Mars, Pennsylvania); Jiangchao Yao (Princeton, New Jersey); Eugen F. Mesaros (Wallingford, Pennsylvania) |
| ABSTRACT | Described herein are certain boron-containing compounds, compositions, preparations and their use as modulators of the transpeptidase function of bacterial penicillin-binding proteins and as antibacterial agents. In some embodiments, the compounds described herein inhibit penicillin-binding proteins. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections. |
| FILED | Friday, May 25, 2018 |
| APPL NO | 16/616382 |
| ART UNIT | 1699 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267832 | Chirayil et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Sara Chirayil (Plano, Texas); Veronica Clavijo Jordan (Dallas, Texas); Andre F. Martins (Plano, Texas); A. Dean Sherry (Dallas, Texas) |
| ABSTRACT | In some aspects, the present disclosure provides compounds of the formula: wherein the variables are defined herein. In some aspects, the present disclosure provides methods of preparing imaging agents, compositions thereof, and methods of imaging using said imaging agents or compositions thereof. |
| FILED | Monday, October 21, 2019 |
| APPL NO | 16/658471 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 49/106 (20130101) Heterocyclic Compounds C07D 213/82 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 13/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267842 | Devaraj et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Neal K. Devaraj (La Jolla, California); Seth C. Alexander (San Diego, California) |
| ABSTRACT | There are provided, inter alia, methods and reagents for labeling nucleic acids. |
| FILED | Thursday, March 03, 2016 |
| APPL NO | 15/553568 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 487/04 (20130101) C07D 519/00 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/022 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 19/04 (20130101) Original (OR) Class C07H 21/00 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/48 (20130101) C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 2521/531 (20130101) Enzymes C12Y 204/02029 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/91142 (20130101) G01N 2500/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267848 | Marshall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Calder Biosciences Inc. (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Marshall (New York, New York); Mark Yondola (New York, New York); Roberto Mariani (New York, New York); Aaron Zomback (Cheshire, Connecticut); Sonal Gidwani (New York, New York) |
| ABSTRACT | The present invention provides mutant RSV F molecules, such as those that can be, or are stabilized, in a pre-fusion conformation by the introduction of one or more DT cross-links. The present invention also provides methods of making such mutant RSV F molecules, compositions comprising such mutant RSV F molecules, and methods of use of such mutant RSV F molecules, for example in vaccination methods, therapeutic methods, and antibody production methods. |
| FILED | Tuesday, August 07, 2018 |
| APPL NO | 16/637155 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/155 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/18522 (20130101) C12N 2760/18534 (20130101) C12N 2760/18571 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267853 | Reshetnyak et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Rhode Island Board of Trustees (Kingston, Rhode Island); Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | University of Rhode Island Board of Trustees (Kingston, Rhode Island); Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Yana K. Reshetnyak (Saunderstown, Rhode Island); Oleg A. Andreev (Saunderstown, Rhode Island); Anna Moshnikova (Warwick, Rhode Island); Donald M. Engelman (New Haven, Connecticut) |
| ABSTRACT | The invention features a compositions and methods for inducing an immune response to targeted cells. The compositions induce targeting of a cell by positioning carbohydrate epitopes on the surface of the cell by conjugation of the epitope to a pH-triggered membrane peptide (pHLIP®). |
| FILED | Tuesday, January 28, 2020 |
| APPL NO | 16/775046 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 47/65 (20170801) A61K 47/646 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/4725 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267855 | Thallapuranam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| INVENTOR(S) | Suresh Kumar Thallapuranam (Fayetteville, Arkansas); Shilpi Agarwal (Fayetteville, Arkansas); Ravi Kumar Gundampati (Fayetteville, Arkansas); Srinivas Jayanthi (Fayetteville, Arkansas); Tengjiao Wang (Fayetteville, Arkansas); Jake Jones (Fayetteville, Arkansas); Olivia Kolenc (Fayetteville, Arkansas); Ngoc Lam (Fayetteville, Arkansas); Isabelle Niyonshuti (Fayetteville, Arkansas); Kartik Balachandran (Fayetteville, Arkansas); Kyle Quinn (Fayetteville, Arkansas); Jingyi Chen (Fayetteville, Arkansas) |
| ABSTRACT | Engineered FGF1 and FGF2 polypeptides, polynucleotides encoding these polypeptides and DNA constructs, vectors and compositions including these engineered polypeptides are provided herein. The engineered FGF1 and FGF2 polypeptides are more stable than their wild-type counterparts and may be more effective at treating a variety of conditions that FGF1 and FGF2 are useful for treating such as wound healing. |
| FILED | Monday, March 18, 2019 |
| APPL NO | 16/356872 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 38/00 (20130101) A61K 38/1825 (20130101) Peptides C07K 14/501 (20130101) Original (OR) Class C07K 14/503 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267867 | Botten et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Vermont and State Agricultural College (Burlington, Vermont) |
| ASSIGNEE(S) | University of Vermont and State Agricultural College (Burlington, Vermont) |
| INVENTOR(S) | Jason Botten (Burlington, Vermont); Joseph Klaus (Burlington, Vermont); Anne Mason (Burlington, Vermont) |
| ABSTRACT | The invention relates, in part, to compounds, compositions, and methods to reduce infectivity of virus particles and to treat viral infections in subjects. |
| FILED | Thursday, April 13, 2017 |
| APPL NO | 16/093520 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/16 (20130101) A61K 38/36 (20130101) A61K 38/1709 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/47 (20130101) C07K 14/745 (20130101) Original (OR) Class C07K 16/18 (20130101) C07K 16/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267875 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Dianqing Wu (Cheshire, Connecticut); Bo Chen (Daly City, California); Hai Wu (Palo Alto, California) |
| ABSTRACT | The present invention relates to the discovery that inhibition of Dickkopf2 (DKK2) increases CD8+ cytotoxic T lymphocyte (CTL) activity, attenuates tumor, and hence suppresses tumor formation. Thus, in various embodiments described herein, the methods of the invention relate to methods of treating cancer by administering to a patient an effective amount of a humanized anti-DKK2 antibody, methods for providing anti-tumor immunity in a subject, methods of stimulating a T cell mediated immune response to a cell population or a tissue and suppressing tumor in a subject. Additionally, the current invention includes methods of diagnosing a cancer or a predisposition of developing a cancer or a metastasis and methods for determining the use of immunotherapy treatment or cancer vaccine for treating cancer. Furthermore, the invention encompasses a pharmaceutical composition for treating cancer as well as a kit for carrying out the aforementioned methods. |
| FILED | Thursday, October 20, 2016 |
| APPL NO | 15/771965 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/001102 (20180801) A61K 39/39558 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/04 (20180101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 16/2818 (20130101) C07K 2317/24 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 33/574 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267895 | Banchereau et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAYLOR RESEARCH INSTITUTE (Dallas, Texas) |
| ASSIGNEE(S) | Baylor Research Institute (Dallas, Texas) |
| INVENTOR(S) | Jacques F. Banchereau (Montclair, New Jersey); Gerard Zurawski (Midlothian, Texas); Sandra Zurawski (Midlothian, Texas); SangKon Oh (Baltimore, Maryland) |
| ABSTRACT | The present invention includes compositions and methods for the expression, secretion and use of novel compositions for use as, e.g., vaccine and antigen delivery vectors, to delivery antigens to antigen presenting cells. In one embodiment, the vector is an anti-CD40 antibody, or fragments thereof, and one or more antigenic peptides linked to the anti-CD40 antibody or fragments thereof, including humanized antibodies. |
| FILED | Monday, June 15, 2020 |
| APPL NO | 16/946302 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 2039/6056 (20130101) Peptides C07K 14/005 (20130101) C07K 16/2878 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/74 (20130101) C07K 2317/80 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2317/626 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16222 (20130101) C12N 2740/16322 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267901 | Fedorov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | Victor D. Fedorov (New York, New York); Michel Sadelain (New York, New York) |
| ABSTRACT | The present invention provides immunoresponsive cells, including T cells, cytotoxic T cells, regulatory T cells, and Natural Killer (NK) cells, expressing an antigen recognizing receptor and an inhibitory chimeric antigen receptor (iCAR). Methods of using the immunoresponsive cell include those for the treatment of neoplasia and other pathologies where an increase in an antigen-specific immune response is desired. |
| FILED | Friday, September 11, 2015 |
| APPL NO | 14/851983 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/0011 (20130101) A61K 39/00117 (20180801) A61K 39/00118 (20180801) A61K 39/001102 (20180801) A61K 39/001106 (20180801) A61K 39/001109 (20180801) A61K 39/001112 (20180801) A61K 39/001113 (20180801) A61K 39/001114 (20180801) A61K 39/001117 (20180801) A61K 39/001119 (20180801) A61K 39/001124 (20180801) A61K 39/001126 (20180801) A61K 39/001128 (20180801) A61K 39/001129 (20180801) A61K 39/001153 (20180801) A61K 39/001157 (20180801) A61K 39/001166 (20180801) A61K 39/001168 (20180801) A61K 39/001171 (20180801) A61K 39/001182 (20180801) A61K 39/001186 (20180801) A61K 39/001188 (20180801) A61K 39/001193 (20180801) A61K 39/001195 (20180801) A61K 2039/5156 (20130101) A61K 2039/5158 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70514 (20130101) C07K 14/70517 (20130101) C07K 16/40 (20130101) Original (OR) Class C07K 2317/622 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268080 | Dong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Min Dong (Weatogue, Connecticut); Lisheng Peng (Guangzhou, China PRC); Liang Tao (Boston, Massachusetts) |
| ABSTRACT | Disclosed herein is a botulinum neurotoxin (BoNT) polypeptide with a modified receptor binding domain (HC) having one or more amino acid mutations that modify the binding of the BoNT to the receptor. Specific mutations and combinations of mutations are also disclosed. Isolated modified HC, polypeptides comprising the modified HC, chimeric molecules, pharmaceutical compositions, and methods of making and using the same are also disclosed. Methods of identifying additional such modified receptor binding domains, are further disclosed. |
| FILED | Friday, March 25, 2016 |
| APPL NO | 15/561355 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/33 (20130101) C07K 2319/50 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) Original (OR) Class C12N 15/1055 (20130101) Enzymes C12Y 304/24069 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/952 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268094 | Prakash et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ionis Pharmaceuticals, Inc. (Carlsbad, California) |
| ASSIGNEE(S) | Ionis Pharmaceuticals, Inc (Carlsbad, California) |
| INVENTOR(S) | Thazha P. Prakash (Carlsbad, California); Punit P. Seth (Carlsbad, California); Eric E. Swayze (Encinitas, California) |
| ABSTRACT | The present invention provides 5′ modified nucleosides and oligomeric compounds prepared therefrom. More particularly, the present invention provides modified nucleosides having at least one 5′-substituent and an optional 2′ substituent, oligomeric compounds comprising at least one of these modified nucleosides and methods of using the oligomeric compounds. In some embodiments, the oligomeric compounds provided herein are expected to hybridize to a portion of a target RNA resulting in loss of normal function of the target RNA. |
| FILED | Thursday, April 30, 2020 |
| APPL NO | 16/863928 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/10 (20130101) C07H 19/067 (20130101) C07H 21/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/32 (20130101) C12N 2320/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268096 | Cruse et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina); The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina); The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Glenn P. Cruse (Apex, North Carolina); Dean D. Metcalfe (Bethesda, Maryland) |
| ABSTRACT | Methods for treating diseases and conditions mediated by the high affinity IgE receptor (FcεRI). Antisense oligomers for modulating splicing of mRNA encoding the FcεRIβ protein, thereby down-regulating cell-surface expression of FcεRI, and uses of the antisense oligomers for inhibiting mast cell degranulation, cytokine release, migration, and proliferation. |
| FILED | Wednesday, August 01, 2018 |
| APPL NO | 16/052130 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 2310/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268099 | Krauss |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brandeis University (Waltham, Massachusetts) |
| ASSIGNEE(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| INVENTOR(S) | Isaac J. Krauss (Waltham, Massachusetts) |
| ABSTRACT | The invention relates to an oligonucleotide including one or more modified nucleoside bases having the structure -B-L-A wherein for each of the modified nucleosides A is independently a monosaccharide or oligosaccharide, Lisa linker molecule, and B is independently a pyrimidine or pyridine base linked to the sugar-phosphate backbone of the oligonucleotide; and wherein the oligonucleotide binds specifically to a carbohydrate-binding monoclonal antibody with an affinity of less than 100 nM. Immunogenic conjugates that include the oligonucleotide, and pharmaceutical compositions that include the oligonucleotide or the immunogenic conjugate are also disclosed. Various method of using the oligonucleotides, immunogenic conjugates, and pharmaceutical compositions are disclosed, including inducing an immune response, inhibiting viral or bacterial infection, treating a cancerous condition, and detecting a neutralizing antibody. A method is also disclosed for selecting the oligonucleotides using an alternative Selection of Modified Aptamers (SELMA). |
| FILED | Monday, August 12, 2019 |
| APPL NO | 16/538291 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) A61K 2039/53 (20130101) A61K 2039/545 (20130101) A61K 2039/572 (20130101) A61K 2039/585 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/117 (20130101) Original (OR) Class C12N 15/1058 (20130101) C12N 2310/16 (20130101) C12N 2310/17 (20130101) C12N 2310/351 (20130101) C12N 2310/531 (20130101) C12N 2320/30 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) G01N 33/6854 (20130101) G01N 33/57415 (20130101) G01N 33/57419 (20130101) G01N 33/57423 (20130101) G01N 33/57434 (20130101) G01N 2333/162 (20130101) G01N 2333/9121 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268100 | Bordenstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Sarah R. Bordenstein (Nashville, Tennessee); Seth R. Bordenstein (Nashville, Tennessee) |
| ABSTRACT | The invention relates to systems, methods, and compositions for the genetic modification of Wolbachia. |
| FILED | Friday, April 14, 2017 |
| APPL NO | 16/093808 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/74 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 2795/10022 (20130101) C12N 2795/10043 (20130101) C12N 2800/30 (20130101) C12N 2800/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268129 | Leng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fenfei Leng (Palmetto Bay, Florida); Zifang Deng (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Fenfei Leng (Palmetto Bay, Florida); Zifang Deng (Miami, Florida) |
| ABSTRACT | The present invention provides assays and methods for studying DNA topology and topoisomerases. The assays and methods utilize a circular plasmid DNA comprising one or more hairpin structures and the ability of T5 exonuclease (T5E) to digest the circular plasmid DNA in a specific configuration. The assays and methods can be used as a high throughput screening for inhibitors of, for example, DNA gyrases and DNA topoisomerases I for anticancer drug and antibiotics discovery. |
| FILED | Thursday, June 10, 2021 |
| APPL NO | 17/343918 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/44 (20130101) C12Q 1/533 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 2021/6439 (20130101) G01N 2500/04 (20130101) G01N 2500/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268148 | Mirmira |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana) |
| ASSIGNEE(S) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana) |
| INVENTOR(S) | Raghavendra G. Mirmira (Zionsville, Indiana) |
| ABSTRACT | Disclosed herein are methods for determining inflammation in subjects. Also disclosed are methods for determining whether a subject has sepsis. The methods include determining methylation of preproinsulin DNA and chromatin target of PRMT1 (CHTOP). |
| FILED | Tuesday, June 18, 2019 |
| APPL NO | 16/444850 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/154 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 35/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268149 | Targan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Stephan R. Targan (Santa Monica, California); Marla C. Dubinsky (Los Angeles, California); Carol J. Landers (Los Angeles, California); Ling Mei (Pasadena, California); Jerome I. Rotter (Los Angeles, California); Kent D. Taylor (Ventura, California) |
| ABSTRACT | This invention provides methods of diagnosis, predicting and diagnosing susceptibility to, predicting disease progression and treatment of inflammatory bowel disease (IBD), including Crohn's disease and/or subtypes of Crohn's disease (CD) and/or Ulcerative Colitis (UC). In one embodiment, a method of the invention is practiced by determining the presence or absence of the genetic variants NOD2, TLR8, TLR2, CARD8, CARD15 and/or JAK3 to diagnose, predict and diagnose susceptibility and predict disease progression in an individual. In another embodiment, a method of the invention is practiced by determining the presence or absence of anti-Cbir1, anti-OmpC, ASCA, anti-I2 and/or pANCA in an individual. In another embodiment, the invention further associates the presence or absence of the risk variants with the expression of anti-Cbir1, anti-OmpC, ASCA, anti-I2 and/or pANCA for the diagnosis, prediction of susceptibility, prediction of disease progression and/or treatment of IBD, including CD and/or UC. |
| FILED | Wednesday, November 13, 2019 |
| APPL NO | 16/683141 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2800/50 (20130101) G01N 2800/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268150 | Green et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Michael R. Green (Boylston, Massachusetts); Sanchita Bhatnagar (Free Union, Virginia) |
| ABSTRACT | In some aspects, the disclosure relates to the reactivation of inactive X chromosomes (Xi). In some embodiments, the disclosure provides compositions and methods for the reactivation of inactive X chromosomes. In some embodiments, the compositions and methods described by the disclosure may be useful for the treatment of dominant X-linked diseases. |
| FILED | Wednesday, June 10, 2020 |
| APPL NO | 16/897549 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2227/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268153 | Vogelstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Luis Diaz (Ellicot City, Maryland); Nickolas Papadopoulos (Towson, Maryland); Nishant Agrawal (Baltimore, Maryland); Yuxuan Wang (Baltimore, Maryland); Simeon Springer (Baltimore, Maryland) |
| ABSTRACT | We queried DNA from saliva or plasma of 93 HNSCC patients, searching for somatic mutations or human papillomavirus genes, collectively referred to as tumor DNA. When both plasma and saliva were tested, tumor DNA was detected in 96% (95% CI, 84% to 99%) of 47 patients. The fractions of patients with detectable tumor DNA in early- and late-stage disease were 100% (n=10) and 95% (n=37), respectively. Saliva is preferentially enriched for tumor DNA from the oral cavity, whereas plasma is preferentially enriched for tumor DNA from the other sites. Tumor DNA in the saliva and plasma is a valuable biomarker for detection of HNSCC. |
| FILED | Thursday, June 16, 2016 |
| APPL NO | 15/739610 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268158 | Sorrentino et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (Memphis, Tennessee) |
| ASSIGNEE(S) | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (Memphis, Tennessee) |
| INVENTOR(S) | Brian P. Sorrentino (Memphis, Tennessee); Sheng Zhou (Memphis, Tennessee) |
| ABSTRACT | The invention is directed to methods of assessing the safety of therapeutic compounds and therapeutic genetic manipulations, including integrating gene therapy vectors and genome editing. In particular, the invention provides a method, wherein the oncogenic potential of therapeutic compounds and therapeutic genetic manipulations, including integrating gene therapy vectors and genome editing, is determined by determining the percentage of differentiation blocked hematopoietic progenitor cells. |
| FILED | Friday, April 22, 2016 |
| APPL NO | 15/136298 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/702 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268892 | Sulchek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Todd Sulchek (Atlanta, Georgia); Alexander Alexeev (Atlanta, Georgia); Bushra Tasadduq (Atlanta, Georgia) |
| ABSTRACT | Embodiments of the present disclosure can include a method comprising: providing a plurality of cells to a microchannel, the microchannel coated in at least one cell adhesion entity and comprising a compressive surface and a first outlet, the compressive surface defining a compression gap, flowing the plurality of cells through the microchannel, wherein the flowing comprises: compressing the plurality of cells underneath the compressive surface; and exposing the plurality of cells to the at least one cell adhesion entity, wherein the exposing causes a first portion of the cells having a first adhesion property to temporarily bind to the cell adhesion entity; and collecting the first portion of cells at the first outlet; wherein the compression gap has a height of from 75% to 95% an average diameter of the plurality of cells. |
| FILED | Wednesday, November 08, 2017 |
| APPL NO | 16/348520 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 3/502776 (20130101) B01L 2200/0652 (20130101) B01L 2200/0668 (20130101) B01L 2300/16 (20130101) B01L 2300/0877 (20130101) B01L 2400/086 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) G01N 15/1056 (20130101) Original (OR) Class G01N 33/5005 (20130101) G01N 2015/1006 (20130101) G01N 2015/1081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268958 | Jain et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Sanjay K. Jain (Baltimore, Maryland); Martin Gilbert Pomper (Baltimore, Maryland); Edward A. Weinstein (Baltimore, Maryland); Alvaro Ordonez (Baltimore, Maryland); Mariah Klunk (Baltimore, Maryland) |
| ABSTRACT | The methods of the present invention exploit unique biochemical pathways present within infectious organisms to develop small molecule metabolic tracers. Labeled substrates created using these inventive methods were created. The labeled substrates can be used to determine whether a subject is infected with an infectious organism by imaging means, and with use of two or more such labeled substrates, methods of differentiating gram negative infection from gram positive infection, and methods of localizing and quantifying infectious disease burden are provided. The methods of the present invention can assist in the clinical decision to begin empiric antibiotic therapy, determine its efficacy, as well as the choice of antibacterial agents. |
| FILED | Monday, September 16, 2013 |
| APPL NO | 14/427774 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5695 (20130101) G01N 33/56916 (20130101) G01N 33/56938 (20130101) G01N 33/56944 (20130101) Original (OR) Class G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268972 | Chan |
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| FUNDED BY |
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| APPLICANT(S) | DNA Medicine Institute, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | DNA Medicine Institute, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Eugene Y. Chan (Boston, Massachusetts) |
| ABSTRACT | A sample consumable that carries a microvolume of sample to a sample loader. The consumable is precisely aligned utilizing a double-alignment feature to the loader. The loader is based on a crank-slider geometry and allows for simple, one-handed operation for the user. Overall, the consumable and sample loader increase reproducibility of in-line sample loading and offers ease-of-use. |
| FILED | Monday, January 14, 2019 |
| APPL NO | 16/247549 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 2200/025 (20130101) B01L 2200/0684 (20130101) B01L 2300/0841 (20130101) Spraying Apparatus; Atomising Apparatus; Nozzles B05B 11/0054 (20130101) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 2583/005 (20130101) Dispensing, Delivering or Transferring Liquids, Not Otherwise Provided for B67D 1/0078 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 35/10 (20130101) Original (OR) Class G01N 35/1011 (20130101) G01N 2035/1039 (20130101) G01N 2035/1051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268973 | Duncan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Texas Tech University System (Lubbock, Texas) |
| ASSIGNEE(S) | TEXAS TECH UNIVERSITY SYSTEM (Lubbock, Texas) |
| INVENTOR(S) | James Duncan (West Palm Beach, Florida); Brian Hirth (Lubbock, Texas); John Schroeder (Lubbock, Texas) |
| ABSTRACT | A system, method, and apparatus are disclosed for determining ABL wind field advection speed and direction comprising collecting at least two wind volumes from the ABL wind field, defining portions of the measurement domain within the at least two wind volumes for analysis, determining the advection of an isolated wind field between the at least two wind volumes, and iterating a process of correcting for intra-volume advection, objective analysis, and determining the inter-volume advective properties; wherein upon convergence of a measured advection profile, the advective properties of the ABL wind field have been appropriately derived. |
| FILED | Friday, March 15, 2019 |
| APPL NO | 16/355471 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 5/001 (20130101) Original (OR) Class G01P 5/26 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/95 (20130101) G01S 17/95 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11269028 | Olsen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Miles E. Olsen (Madison, Wisconsin); Ethan K. Brodsky (Madison, Wisconsin); Walter F. Block (Madison, Wisconsin) |
| ABSTRACT | A system and methods are provided for controlling interventional devices using magnetic resonance imaging (“MRI”) guidance. In some aspects, the method includes arranging a pivoting guide about a subject's anatomy that is configured to direct an interventional device toward a selected target point within the subject's anatomy, generating, using an MRI system, MR data associated with markers placed on the pivoting guide, and determining a vector defining an orientation of the pivoting guide from locations for the markers identified using the MR data. The method also includes orienting the pivoting guide in multiple directions to determine multiple vectors, and identifying a pivot point for the pivoting guide using the determined vectors. The method further includes determining a trajectory for the interventional device using the identified pivot point and the selected target point, and controlling the interventional device along the determined trajectory. |
| FILED | Friday, May 29, 2015 |
| APPL NO | 14/725847 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/02 (20130101) A61B 17/3403 (20130101) A61B 34/10 (20160201) A61B 90/11 (20160201) A61B 2090/374 (20160201) A61B 2090/3954 (20160201) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/286 (20130101) G01R 33/287 (20130101) Original (OR) Class G01R 33/4824 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11269084 | Meng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Ling-Jian Meng (Champaign, Illinois); Xiaochun Lai (Arlington Heights, Illinois); Elena Maria Zannoni (Champaign, Illinois) |
| ABSTRACT | Aspects of the subject disclosure may include, for example, a device comprising: a first micro-camera-element comprising a first sensor area and a first aperture element, the first aperture element having a first structural configuration, the first aperture element and the first sensor area being disposed relative to each other in order to cooperate in obtaining first imaging data having first characteristics, and the first characteristics comprising first imaging resolution and first angular coverage; a second micro-camera-element comprising a second sensor area and a second aperture element, the second aperture element having a second structural configuration, the second aperture element and the second sensor area being disposed relative to each other in order to cooperate in obtaining second imaging data having second characteristics, the second characteristics comprising second imaging resolution and second angular coverage, and the first imaging resolution differing from the second imaging resolution, the first angular coverage differing from the second angular coverage, or any combination thereof. Additional embodiments are disclosed. |
| FILED | Tuesday, September 24, 2019 |
| APPL NO | 16/580711 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/1642 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11269169 | Hillman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Elizabeth M. C. Hillman (New York, New York); Kripa B. Patel (Salem, New Hampshire) |
| ABSTRACT | In some embodiments, a SCAPE system routes light from a tilted intermediate image plane to an infinity space disposed behind a third objective. A first beam splitter positioned in the infinity space routes light from the intermediate image plane with different wavelengths in different directions. First and second light detector arrays capture first and second wavelength images, respectively, and optical components route light having the first and second wavelength towards the first and second light detectors, respectively. In some embodiments, a SCAPE system is used to capture a plurality of images while a sample is perturbed (e.g., vibrated, deformed, pushed, pulled, stretched, or squeezed) in order to visualize the impact of the perturbation on the sample. |
| FILED | Tuesday, December 03, 2019 |
| APPL NO | 16/701984 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/36 (20130101) G01J 3/2803 (20130101) G01J 2003/2826 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0032 (20130101) G02B 21/0036 (20130101) G02B 21/0048 (20130101) Original (OR) Class G02B 21/0064 (20130101) G02B 21/0076 (20130101) G02B 21/367 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11269176 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Hongrui Jiang (Madison, Wisconsin); Alireza Ousati Ashtiani (Madison, Wisconsin) |
| ABSTRACT | A optical phase shifter is provided for adjusting an optical phase of light propagating therethrough along an optical axis. The optical phase shifter includes first and second transparent slides defining a cavity therebetween. A sheet is received in the cavity and has first and second sides. The sheet includes a rigid inner portion alignable with the optical axis and is moveable along the optical axis between a first position and a second position. A tuning structure is operatively engageable with the rigid inner portion of the sheet to selectively move the rigid inner portion of the sheet along the optical axis so as to adjust the optical phase of light propagating through the optical phase shifter. |
| FILED | Thursday, June 13, 2019 |
| APPL NO | 16/440202 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 26/005 (20130101) Original (OR) Class G02B 2207/115 (20130101) G02B 2207/117 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11269401 | West et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
| ASSIGNEE(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
| INVENTOR(S) | Karl West (Geneva, Ohio); Jeffrey H. Yanof (Solon, Ohio) |
| ABSTRACT | Holographic image-guidance can be used to track an interventional device during a non-vascular percutaneous procedure. The holographic image guidance can be provided by a head-mounted device by transforming tracking data and body image data to a common coordinate system and creating a holographic display relative to a patient's body to track the interventional device during the non-vascular percutaneous procedure. The holographic display can also include graphics to provide guidance for the physical interventional device as it travels through the patient's anatomy. |
| FILED | Monday, November 09, 2020 |
| APPL NO | 17/092409 |
| ART UNIT | 2622 — Selective Visual Display Systems |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/062 (20130101) A61B 5/064 (20130101) A61B 5/745 (20130101) A61B 5/6852 (20130101) A61B 5/7405 (20130101) A61B 34/20 (20160201) A61B 34/25 (20160201) A61B 90/37 (20160201) A61B 90/361 (20160201) A61B 2034/102 (20160201) A61B 2034/107 (20160201) A61B 2034/2051 (20160201) A61B 2034/2057 (20160201) A61B 2034/2068 (20160201) A61B 2090/363 (20160201) A61B 2090/365 (20160201) A61B 2090/366 (20160201) A61B 2090/367 (20160201) A61B 2090/368 (20160201) A61B 2090/372 (20160201) A61B 2090/502 (20160201) A61B 2090/3762 (20160201) A61B 2090/3983 (20160201) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/00 (20130101) A61M 2205/507 (20130101) Optical Elements, Systems, or Apparatus G02B 2027/0174 (20130101) Electric Digital Data Processing G06F 3/011 (20130101) Original (OR) Class G06F 3/012 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00671 (20130101) G06K 9/3216 (20130101) G06K 2009/3225 (20130101) G06K 2209/05 (20130101) Image Data Processing or Generation, in General G06T 3/0006 (20130101) G06T 3/20 (20130101) G06T 7/344 (20170101) G06T 17/20 (20130101) G06T 19/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11270098 | Thompson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Silver Spring, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Silver Spring, Maryland) |
| INVENTOR(S) | Elaine Ellen Thompson (Silver Spring, Maryland); Vahan Simonyan (Rockville, Maryland); Malcolm Moos, Jr. (Silver Spring, Maryland) |
| ABSTRACT | Methods are disclosed for clustering biological samples and other objects using a grand canonical ensemble. A biological sample is characterized by data attributes from varying sources (e.g. NGS, other types of high-dimensional cytometric data, observed disease state) and of varying data types (e.g. Boolean, continuous, or coded sets) organized as vectors (as many as 109) having as many as 106, 109, or more components. The biological samples or observational data are modeled as particles of a grand canonical ensemble which can be variably distributed among partitions. A pseudo-energy is defined as a measure of inverse similarity between the particles. Minimization of grand canonical ensemble pseudo-energy corresponds to clustering maximally similar particles in each partition, thereby determining clusters of the biological samples. The sample clusters can be used for feature discovery, gene and pathway identification, and development of cell based therapeutics, or for other purposes. Variations and additional applications are disclosed. |
| FILED | Thursday, November 15, 2018 |
| APPL NO | 16/764557 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0014 (20130101) G06K 9/00147 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/30024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11270445 | Frank et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Lawrence R. Frank (San Diego, California); Vitaly L. Galinsky (San Diego, California) |
| ABSTRACT | A method for registering multiple data types of diverse modalities for a target volume includes acquiring at least at least two datasets associated with the target volume where the at least two datasets having different modalities. Using information field theory and entropy spectrum pathways theory, a local connectivity matrix is constructed for one or both of spatial connectivity and temporal connectivity for each of the datasets. The local connectivity matrices for the datasets are fused into a common coupling matrix and the datasets are merged to generate a registered image displaying the spatial and temporal features within the target volume. |
| FILED | Tuesday, March 06, 2018 |
| APPL NO | 16/491144 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/30 (20170101) Original (OR) Class G06T 2207/10044 (20130101) G06T 2207/10092 (20130101) G06T 2207/30016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11270479 | Pan et al. |
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| FUNDED BY |
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| APPLICANT(S) | KONINKLIJKE PHILIPS N.V. (Eindhoven, Netherlands); UNIVERSITY OF CHICAGO (Chicago, Illinois) |
| ASSIGNEE(S) | KONINKLIJKE PHILIPS N.V. (Eindhoven, Netherlands); UNIVERSITY OF CHICAGO (Chicago, Illinois) |
| INVENTOR(S) | Xiaochuan Pan (Chicago, Illinois); Jinghan Ye (Livermore, California); Amy Perkins (Philadelphia, Pennsylvania); Chi-Hua Tung (Aurora, Ohio); Zheng Zhang (Chicago, Illinois) |
| ABSTRACT | In an emission imaging method, emission imaging data are acquired for a subject using an emission imaging scanner (10) including radiation detectors (12). The emission imaging data are reconstructed to generate a reconstructed image by executing a constrained optimization program including a measure of data fidelity between the acquired emission imaging data an a reconstruct-image transformed by a data model of the imaging scanner to emission imaging data. During the reconstructing, each iteration of the constrained optimization program is constrained by an image variability constraint. The reconstructed image is displayed the reconstructed image on a display device. The emission imaging may be positron emission tomography (PET) imaging data, optionally acquired using a sparse detector array. The image variability constraint may be a constraint that an image total variation (image TV) of a latent image defined using a Gaussian blurring matrix be less than a maximum value. |
| FILED | Monday, February 13, 2017 |
| APPL NO | 16/070791 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/037 (20130101) A61B 6/461 (20130101) A61B 6/467 (20130101) A61B 6/4275 (20130101) A61B 6/5205 (20130101) Image Data Processing or Generation, in General G06T 11/006 (20130101) Original (OR) Class G06T 2211/424 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11271226 | Saraidaridis et al. |
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| FUNDED BY |
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| APPLICANT(S) | Raytheon Technologies Corporation (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Waltham, Massachusetts) |
| INVENTOR(S) | James D. Saraidaridis (Hartford, Connecticut); Michael L. Perry (Groton, Connecticut); Robert Mason Darling (South Windsor, Connecticut) |
| ABSTRACT | A method for a redox flow battery includes using a cell of a redox flow battery to store electrical energy and discharge the stored electrical energy. The using includes circulating a first electrolyte solution through a first circulation loop in fluid connection with the first electrode of the cell; circulating a second electrolyte solution through a second circulation loop in fluid connection with the second electrode of the cell; and at least one of a first element from the first electrolyte solution in the first electrode permeates through the separator layer and precipitates as a first solid product in the second electrode and a second element from the second electrolyte solution permeates through the separator layer and precipitates a second solid product in the first electrode. The method also includes removing at least a portion of the first solid product or the second solid product from the first electrode and the second electrode, respectively. |
| FILED | Friday, December 11, 2020 |
| APPL NO | 17/119427 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/08 (20130101) H01M 8/188 (20130101) H01M 8/04186 (20130101) Original (OR) Class H01M 8/04201 (20130101) H01M 2300/0002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE48960 | Wilton et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Western Australia (Crawley, Australia) |
| ASSIGNEE(S) | The University of Western Australia (Crawley, Australia) |
| INVENTOR(S) | Stephen Donald Wilton (Applecross, Australia); Sue Fletcher (Bayswater, Australia); Graham McClorey (Bayswater, Australia) |
| ABSTRACT | An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 202. |
| FILED | Thursday, December 19, 2019 |
| APPL NO | 16/721681 |
| ART UNIT | 3991 — Central Reexamination Unit (Chemical) |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/33 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/3233 (20130101) C12N 2310/3341 (20130101) C12N 2310/3519 (20130101) C12N 2320/30 (20130101) C12N 2320/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11266381 | Heikenfeld et al. |
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| FUNDED BY |
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| APPLICANT(S) | University Of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | University Of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Jason Charles Heikenfeld (Cincinnati, Ohio); Zachary Cole Sonner (Elsmere, Kentucky) |
| ABSTRACT | A sweat sensing device includes a plurality of sweat collection pads communicating with a sensor. Each of the pads is activated by a timing circuit which allows one or more of the pads to be activated at a selected time and subsequent deactivated after a defined period of time. This allows for selective collection of sweat from a plurality of pads over a prolonged period of time. An impedance measuring circuit can be employed to determine if one or more of the pads becomes disconnected, in order to avoid irritation. Further, the devices can use a common microfluidic device which both transports sweat activating substance, such as pilocarpine, to the surface of the skin and directs sweat away from the skin to a sensing device. |
| FILED | Thursday, December 13, 2018 |
| APPL NO | 16/218586 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/282 (20210101) A61B 5/0531 (20130101) A61B 5/0537 (20130101) A61B 5/1491 (20130101) A61B 5/4266 (20130101) A61B 5/6843 (20130101) A61B 5/14521 (20130101) A61B 10/0064 (20130101) Original (OR) Class A61B 2010/0009 (20130101) A61B 2562/168 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 2202/092 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266606 | Vegas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Arturo J. Vegas (Belmont, Massachusetts); Joshua C. Doloff (Quincy, Massachusetts); Omid Veiseh (Bellaire, Texas); Minglin Ma (Ithaca, New York); Robert S. Langer (Newton, Massachusetts); Daniel G. Anderson (Framingham, Massachusetts) |
| ABSTRACT | Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates are useful as a matrix for coating of any material where reduced fibrosis is desired, such as encapsulated cells for transplantation and medical devices implanted or used in the body. |
| FILED | Thursday, September 26, 2019 |
| APPL NO | 16/584170 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 9/5036 (20130101) Original (OR) Class A61K 35/39 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/085 (20130101) A61L 29/085 (20130101) A61L 31/10 (20130101) A61L 31/10 (20130101) A61L 33/08 (20130101) A61L 33/08 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0084 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) C08L 5/04 (20130101) C08L 5/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0012 (20130101) C12N 5/0677 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266626 | Schon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Eric A. Schon (Bronx, New York); Estela Area-Gomez (New York, New York) |
| ABSTRACT | The invention provides for methods for treating Alzheimer's Disease in a subject by reducing ER-MAM localized APP-C99. |
| FILED | Friday, March 09, 2018 |
| APPL NO | 15/917344 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/11 (20130101) A61K 31/37 (20130101) A61K 31/40 (20130101) A61K 31/55 (20130101) A61K 31/137 (20130101) A61K 31/166 (20130101) A61K 31/192 (20130101) A61K 31/197 (20130101) A61K 31/327 (20130101) A61K 31/366 (20130101) A61K 31/397 (20130101) Original (OR) Class A61K 31/513 (20130101) A61K 31/519 (20130101) A61K 31/519 (20130101) A61K 31/566 (20130101) A61K 31/675 (20130101) A61K 31/4188 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266695 | Lodish et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| INVENTOR(S) | Harvey Lodish (Brookline, Massachusetts); Hidde L. Ploegh (Brookline, Massachusetts); Hsiang-Ying Sherry Lee (Cambridge, Massachusetts); Jiahai Shi (Kowloon, China Hong Kong); Lenka Hoffman (Malden, Massachusetts); Novalia Pishesha (Cambridge, Massachusetts) |
| ABSTRACT | Methods for the in vitro production of enucleated red blood cells and the enucleated red blood cells thus prepared are provided. Such enucleated red blood cells may express a sortaggable surface protein, which allows for surface modification in the presence of a sortase. Also described herein are surface modified enucleated red blood cells, e.g., conjugated with an agent of interest such as a peptide, a detectable label, or a chemotherapeutic agent, and uses thereof in delivering the agent to a subject. |
| FILED | Friday, March 23, 2018 |
| APPL NO | 15/934177 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 2217/072 (20130101) A01K 2227/105 (20130101) A01K 2267/03 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/18 (20130101) Original (OR) Class Peptides C07K 14/47 (20130101) C07K 14/705 (20130101) C07K 14/70582 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0641 (20130101) C12N 2501/14 (20130101) C12N 2501/26 (20130101) C12N 2501/125 (20130101) C12N 2501/999 (20130101) C12N 2501/2303 (20130101) C12N 2501/2306 (20130101) C12N 2506/11 (20130101) C12N 2510/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266712 | Jaynes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Riptide Bioscience, Inc. (Vallejo, California) |
| ASSIGNEE(S) | Riptide Bioscience, Inc. (Vallejo, California) |
| INVENTOR(S) | Jesse M. Jaynes (Auburn, Alabama); L. Edward Clemens (Bainbridge Island, Washington); Henry Wilfred Lopez (Napa, California); George R. Martin (Rockville, California); Kathryn Woodburn (Saratoga, California) |
| ABSTRACT | Aspects of the present invention relate to peptides having antimicrobial activity. In certain aspects, the invention relates to peptides having potent antimicrobial activity, broad-spectrum antimicrobial activity, and/or the ability to kill otherwise antibiotic-resistant microbes, or microbes protected by biofilms. |
| FILED | Friday, January 24, 2020 |
| APPL NO | 16/752037 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0053 (20130101) A61K 9/0073 (20130101) A61K 38/10 (20130101) Original (OR) Class A61K 38/16 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) A61P 31/10 (20180101) Peptides C07K 7/08 (20130101) C07K 14/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266980 | Porosoff et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Marc Porosoff (Washington, District of Columbia); Heather D. Willauer (Fairfax Station, Virginia) |
| ABSTRACT | A method for CO2 hydrogenation via the reverse water-gas shift (RWGS) reaction using alkali metal-doped molybdenum carbide, supported on gamma alumina (A-Mo2C/γ-Al2O3, A=K, Na, Li). The A-Mo2C/γ-Al2O3 catalyst is synthesized by co-impregnation of molybdemun and alkali metal precursors onto a γ-Al2O3 support. It is then carburized to form the A-Mo2C/γ-Al2O3. Also disclosed is the related catalyst material. |
| FILED | Thursday, July 11, 2019 |
| APPL NO | 16/508474 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/02 (20130101) B01J 21/04 (20130101) B01J 27/22 (20130101) Original (OR) Class B01J 37/08 (20130101) B01J 37/084 (20130101) B01J 37/0201 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/40 (20170801) C01B 32/949 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267516 | Roberts et al. |
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| FUNDED BY |
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| APPLICANT(S) | Justin M Roberts (Florence, Mississippi); John M Hoemann (Vicksburg, Mississippi); Craig R Ackerman (Gainesville, Virginia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
| INVENTOR(S) | Justin M Roberts (Florence, Mississippi); John M Hoemann (Vicksburg, Mississippi); Craig R Ackerman (Gainesville, Virginia) |
| ABSTRACT | A Hardened Alternative Trailer System (HATS) is described, including methods of producing same. HATS has superior blast, ballistic and forced entry protection properties, relative to existing structures, due to particular features of frame design and construction methods. Furthermore, HATS is a low-cost reinforced ISO container suitable for field and/or remote fabrication and meets blast, ballistic/projectile and/or forced entry threats such as the U.S. Department of State Certification Standard SD-STD-01.01, Revision G. |
| FILED | Thursday, May 02, 2013 |
| APPL NO | 13/886248 |
| ART UNIT | 3733 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 31/02 (20130101) Motor Vehicles; Trailers B62D 27/023 (20130101) Original (OR) Class Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 88/121 (20130101) Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General E04H 9/10 (20130101) E04H 2001/1283 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267981 | Duncan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Bradley P. Duncan (Sandwich, Massachusetts); Maxwell E. Plaut (Cambridge, Massachusetts); Theodore H. Fedynyshyn (Sudbury, Massachusetts); Jennifer A. Lewis (Cambridge, Massachusetts) |
| ABSTRACT | A 3-D printed device comprising one or more interconnect structures, the interconnect structures comprising a plurality of conductive particles and one or more diblock or triblock copolymers; the diblock or triblock copolymers having an A-B, A-B-A, or A-B-C block-type structure in which the A-blocks and C-blocks are an aromatic-based polymer or an acrylate-based polymer and the B-blocks are an aliphatic-based polymer. These 3-D printed devices may be formed using a method that comprises providing a conductive ink composition; applying the conductive ink composition to a substrate in a 3-D solvent cast printing process to form one or more interconnect structures; and drying the one or more interconnect structures formed from the conductive ink composition. The dried interconnect structures exhibit a conductivity equal to or greater than 1×105 S/m without having to be subjected to any post-processing sintering treatment. |
| FILED | Friday, March 29, 2019 |
| APPL NO | 16/370210 |
| ART UNIT | 1781 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2096/04 (20130101) B29K 2105/0085 (20130101) B29K 2505/00 (20130101) B29K 2995/0005 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/033 (20130101) C09D 11/037 (20130101) C09D 11/52 (20130101) Original (OR) Class C09D 11/108 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268036 | Strohm et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | James J. Strohm (Allison Park, Pennsylvania); Benjamin Q. Roberts (Seven Fields, Pennsylvania); Tricia D. Smurthwaite (Pasco, Washington); Theresa M. Bergsman (Richland, Washington); Mark D. Bearden (Richland, Washington) |
| ABSTRACT | Conversion of heavy fossil hydrocarbons (HFH) to a variety of value-added chemicals and/or fuels can be enhanced using microwave (MW) and/or radio-frequency (RE) energy. Variations of reactants, process parameters, and reactor design can significantly influence the relative distribution of chemicals and fuels generated as the product. In one example, a system for flash microwave conversion of HFH includes a source concentrating microwave or RF energy in a reaction zone having a pressure greater than 0.9 atm, a continuous feed having HFH and a process gas passing through the reaction zone, a HFH-to-liquids catalyst contacting the HFH in at least the reaction zone, and dielectric discharges within the reaction zone. The HFH and the catalyst have a residence time in the reaction zone of less than 30 seconds. In some instances, a plasma can form in or near the reaction zone. |
| FILED | Tuesday, January 02, 2018 |
| APPL NO | 15/860638 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/088 (20130101) B01J 19/0093 (20130101) B01J 19/126 (20130101) B01J 2219/0086 (20130101) B01J 2219/00792 (20130101) B01J 2219/00822 (20130101) B01J 2219/00826 (20130101) B01J 2219/00835 (20130101) B01J 2219/0894 (20130101) B01J 2219/00941 (20130101) B01J 2219/1215 (20130101) B01J 2219/1227 (20130101) B01J 2219/1239 (20130101) B01J 2219/1245 (20130101) B01J 2219/1269 (20130101) B01J 2219/1272 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 1/002 (20130101) C10G 15/08 (20130101) Original (OR) Class C10G 29/205 (20130101) C10G 2300/1033 (20130101) C10G 2400/02 (20130101) C10G 2400/04 (20130101) C10G 2400/08 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/46 (20130101) H05H 1/4622 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268105 | Perkins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SynPloid Biotek, LLC (Savannah, Georgia) |
| ASSIGNEE(S) | CarryGenes Bioengineering (Savannah, Georgia) |
| INVENTOR(S) | Edward Perkins (Savannah, Georgia); Amy Greene (Savannah, Georgia); Dominique Broccoli (Savannah, Georgia) |
| ABSTRACT | The present invention encompasses compositions and methods to rejuvenate cells by, expanding the replicative life span of the cells for, e.g., use in regenerative therapies. Specifically, the methods and compositions of the present invention increase the proliferation capacity and differentiation capacity and plasticity of cells. |
| FILED | Friday, December 15, 2017 |
| APPL NO | 15/844014 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/80 (20130101) C12N 9/1276 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 15/907 (20130101) C12N 2800/30 (20130101) C12N 2830/003 (20130101) Enzymes C12Y 207/07049 (20130101) C12Y 305/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268111 | Lynch et al. |
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| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Michael David Lynch (Durham, North Carolina); Zhixia Ye (Raleigh, North Carolina) |
| ABSTRACT | The present disclosure provides compositions and methods for rapid production of chemicals in genetically engineered microorganisms in a large scale. Also provided herein is a high-throughput metabolic engineering platform enabling the rapid optimization of microbial production strains. The platform, which bridges a gap between current in vivo and in vitro bio-production approaches, relies on dynamic minimization of the active metabolic network. |
| FILED | Wednesday, February 21, 2018 |
| APPL NO | 16/487542 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/001 (20130101) C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/0016 (20130101) C12N 9/0051 (20130101) C12N 9/1025 (20130101) C12N 15/746 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/42 (20130101) Original (OR) Class C12P 13/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268387 | Quach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | San Quach (Southington, Connecticut); Tracy A. Propheter-Hinckley (Rocky Hill, Connecticut); Dominic J. Mongillo, Jr. (West Hartford, Connecticut); Steven Bruce Gautschi (Milton, Massachusetts) |
| ABSTRACT | A component for a gas turbine engine includes a trailing edge tip corner that at least partially defines a trailing edge cavity and a multiple of corner features within the trailing edge cavity, the multiple of corner features splayed along the trailing edge tip corner. |
| FILED | Friday, January 04, 2019 |
| APPL NO | 16/239689 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Foundry Moulding B22C 9/103 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/147 (20130101) Original (OR) Class F01D 5/187 (20130101) F01D 5/284 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/21 (20130101) F05D 2240/304 (20130101) F05D 2240/307 (20130101) F05D 2260/2212 (20130101) F05D 2300/6033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268402 | Hart et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Adam Lee Hart (Stuart, Florida); Brian Levy (Sunny Isles Beach, Florida); Luis Miguel Ayalde (Weston, Florida); Jose R. Paulino (Saco, Maine); Patrick Scheelk (Jensen Beach, Florida); Nicolas Bueno (St. Johns, Florida) |
| ABSTRACT | A blade outer air seal (BOAS) for a gas turbine engine according to one disclosed non-limiting embodiment of the present disclosure includes a seal body having a radially inner face and a radially outer face that axially extend between a leading edge portion and a trailing edge portion; and a multitude of cooling fins disposed around the radially outer face of the seal body, at least one of the multitude of cooling fins having at least one aperture. |
| FILED | Wednesday, April 11, 2018 |
| APPL NO | 15/950549 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/08 (20130101) F01D 25/12 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/237 (20130101) F05D 2240/11 (20130101) F05D 2240/14 (20130101) F05D 2250/11 (20130101) F05D 2250/283 (20130101) F05D 2260/22141 (20130101) F05D 2300/17 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268550 | Taira et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Kunihiko Taira (Tallahassee, Florida); Farrukh Alvi (Tallahassee, Florida); Phillip Munday (Niceville, Florida) |
| ABSTRACT | A method of controlling a fluid flow using momentum and/or vorticity injections. Actively controlling an actuator allows for direct, precise, and independent control of the momentum and swirl entering into the fluid system. The perturbations are added to the flow field in a systematic mater providing tunable control input, thereby modifying behavior thereof in a predictable manner to improve the flow characteristics. |
| FILED | Wednesday, May 29, 2019 |
| APPL NO | 16/425327 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 21/08 (20130101) Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/007 (20130101) F15D 1/009 (20130101) Original (OR) Class F15D 1/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268810 | Sabater |
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| FUNDED BY |
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| APPLICANT(S) | Government of the United States as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Andrew B. Sabater (San Diego, California) |
| ABSTRACT | Compared to amplitude modulated gyroscopes, frequency modulated (FM) gyroscopes have demonstrated excellent long-term stability. A notable limitation with FM gyroscopes is FM operation can decrease short-term stability. Short-term stability is typically quantified via angle random walk (ARW). The present disclosure provides an FM gyroscope ARW minimization method. |
| FILED | Wednesday, July 10, 2019 |
| APPL NO | 16/507453 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/5712 (20130101) G01C 19/5776 (20130101) Original (OR) Class Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268812 | Zell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Eric J Zell (Scituate, Massachusetts); David J Bamford (Wakefield, Rhode Island); Ahmed S Zaki (Kingston, Rhode Island) |
| ABSTRACT | A method and system is provided for estimating and compensating for gyro bias in gyro-stabilized systems. The method includes comparing an output of a gyroscope to a reference measurement; estimating a bias of the gyroscope based on the comparison using a Kalman filter; and adjusting a control output of the gyro-stabilized system with the estimated bias to maintain a position of the gyro-stabilized system. |
| FILED | Thursday, September 10, 2020 |
| APPL NO | 17/016432 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/721 (20130101) Original (OR) Class G01C 19/5776 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268818 | Young et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRX SYSTEMS, INC. (Greenbelt, Maryland) |
| ASSIGNEE(S) | TRX SYSTEMS, INC. (Greenbelt, Maryland) |
| INVENTOR(S) | Travis Young (Rockville, Maryland); Kamiar Kordari (McLean, Virginia); Benjamin Funk (Hanover, Maryland); Carole Teolis (Glenn Dale, Maryland) |
| ABSTRACT | A location and mapping service is described that creates a global database of indoor navigation maps through crowd-sourcing and data fusion technologies. The navigation maps consist of a database of geo-referenced, uniquely described features in the multi-dimensional sensor space (e.g., including structural, RF, magnetic, image, acoustic, or other data) that are collected automatically as a tracked mobile device is moved through a building (e.g. a person with a mobile phone or a robot). The feature information can be used to create building models as one or more tracked devices traverse a building. |
| FILED | Wednesday, April 17, 2019 |
| APPL NO | 16/387483 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/32 (20130101) G01C 21/165 (20130101) G01C 21/206 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/0252 (20130101) G01S 19/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268854 | Han et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Seunghoon Han (Seoul, South Korea); Amir Arbabi (Pasadena, California); Andrei Faraon (Pasadena, California); Ehsan Arbabi (Pasadena, California); Hyeonsoo Park (Suwon-si, South Korea) |
| ABSTRACT | A spectrometer includes a substrate; a slit which is provided on the substrate and through which light is incident onto the substrate; a metasurface including nanostructures that is configured to reflect and focus the light incident thereon through the slit, at different angles based on respective wavelengths; and a sensor which is provided on one side of the substrate that is opposite to another side of the substrate at which the metasurface is disposed, and configured to receive the light from the metasurface. |
| FILED | Friday, November 08, 2019 |
| APPL NO | 16/677792 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/04 (20130101) Original (OR) Class G01J 3/027 (20130101) G01J 3/0208 (20130101) Optical Elements, Systems, or Apparatus G02B 5/1871 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268856 | Mitchell |
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| FUNDED BY |
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| APPLICANT(S) | Wavefront Research, Inc. (Northampton, Pennsylvania) |
| ASSIGNEE(S) | Wavefront Research, Inc. (Northhampton, Pennsylvania) |
| INVENTOR(S) | Thomas A. Mitchell (Northampton, Pennsylvania) |
| ABSTRACT | An imaging optical system including a plurality of imaging optical sub-systems, each having at least one optical element and receiving light from a source, and a plurality of spectrometer optical sub-systems, each spectrometer optical sub-system receiving light from at least one of the imaging optical sub-systems, each imaging optical sub-system and spectrometer optical sub-system combination having a spatial distortion characteristic, each spatial distortion characteristic having a predetermined relationship to the other spatial distortion characteristics. |
| FILED | Monday, December 28, 2020 |
| APPL NO | 17/135204 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/02 (20130101) G01J 3/14 (20130101) G01J 3/18 (20130101) G01J 3/28 (20130101) G01J 3/36 (20130101) G01J 3/0208 (20130101) G01J 3/2823 (20130101) Original (OR) Class G01J 2003/2826 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268924 | Gupta |
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| FUNDED BY |
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| APPLICANT(S) | ProbiusDx (El Cerrito, California); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | ProbiusDx, Inc. (El Cerrito, California); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Chaitanya Gupta (San Carlos, California) |
| ABSTRACT | A sensor can selectively detect quantum signatures in charge transfer processes via a tunneling current. In one aspect, the sensor can include a metal electrode having a first surface and a second surface. The sensor can also include an insulator film having a first thickness, a first surface area and a first surface chemistry. The insulator film can be coupled to the metal electrode via the first surface. The sensor can also include a functionalization film having a second thickness, a second surface area and a second surface chemistry. The functionalization film can be coupled to the metal electrode via the second surface. The insulator film and the functionalization film are configured to separate the metal electrode from an electrochemical solution comprising the analyte. |
| FILED | Friday, June 22, 2018 |
| APPL NO | 16/016468 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/30 (20130101) Original (OR) Class G01N 27/48 (20130101) G01N 27/416 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11269119 | Larsen |
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| FUNDED BY |
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| APPLICANT(S) | United States of America, as represented by the Secretary of the Army (Fort Belvoir, Virginia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia) |
| INVENTOR(S) | Kim W. Larsen (Alexandria, Virginia) |
| ABSTRACT | A monolithic double diffractive kinoform doublet and a method for making such optical element is disclosed. In one embodiment, the optical element includes a first lens and a second lens. The first lens has a first refractive index. The first lens also has a first surface and a second surface. The first surface is a continuous, potentially flat surface for optical radiation to enter. The second lens has a second refractive index different from the first refractive index. The second lens has a first surface and a second surface. The first surface is in contact with the second surface of the first lens. The optical element has a peak diffraction efficiency at a first wavelength and at a second wavelength different than the first wavelength. |
| FILED | Wednesday, October 30, 2019 |
| APPL NO | 16/667938 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/1852 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11269149 | Fink et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Yoel Fink (Brookline, Massachusetts); Michael Rein (Boston, Massachusetts) |
| ABSTRACT | Provided is a fabric including a plurality of fibers disposed in a fabric configuration. At least one of the fibers comprises a device fiber having a device fiber body including a device fiber body material, having a longitudinal axis along a device fiber body length. A plurality of discrete devices are disposed as a linear sequence within the device fiber body along at least a portion of the device fiber body length. Each discrete device includes at least one electrical contact pad. The device fiber body includes device fiber body material regions disposed between adjacent discrete devices in the linear sequence, separating adjacent discrete devices. At least one electrical conductor is disposed within the device fiber body along at least a portion of the device fiber body length. The electrical conductor is disposed in electrical connection with an electrical contact pad of discrete devices within the device fiber body. |
| FILED | Wednesday, November 20, 2019 |
| APPL NO | 16/689453 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 1/005 (20130101) Non-portable Lighting Devices; Systems Thereof; Vehicle Lighting Devices Specially Adapted for Vehicle Exteriors F21S 4/10 (20160101) F21S 4/15 (20160101) Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 23/001 (20130101) Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to the Form or the Kind of the Light Sources or of the Colour of the Light Emitted F21Y 2103/30 (20160801) F21Y 2115/10 (20160801) Optical Elements, Systems, or Apparatus G02B 6/02033 (20130101) G02B 6/4416 (20130101) Original (OR) Class G02B 6/4479 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/023 (20130101) H01B 1/026 (20130101) H01B 3/30 (20130101) H01B 5/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11269629 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Zhengya Zhang (Ann Arbor, Michigan); Thomas Chen (Ann Arbor, Michigan); Jacob Christopher Botimer (Ann Arbor, Michigan); Shiming Song (Ann Arbor, Michigan) |
| ABSTRACT | Many signal processing, machine learning and scientific computing applications require a large number of multiply-accumulate (MAC) operations. This type of operation is demanding in both computation and memory. Process in memory has been proposed as a new technique that computes directly on a large array of data in place, to eliminate expensive data movement overhead. To enable parallel multi-bit MAC operations, both width- and level-modulating memory word lines are applied. To improve performance and provide tolerance against process-voltage-temperature variations, a delay-locked loop is used to generate fine unit pulses for driving memory word lines and a dual-ramp Single-slope ADC is used to convert bit line outputs. The concept is prototyped in a 180 nm CMOS test chip made of four 320×64 compute-SRAMs, each supporting 128× parallel 5 b×5 b MACs with 32 5 b output ADCs and consuming 16.6 mW at 200 MHz. |
| FILED | Thursday, November 29, 2018 |
| APPL NO | 16/204153 |
| ART UNIT | 2182 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 7/5443 (20130101) G06F 9/3001 (20130101) Original (OR) Class G06F 17/13 (20130101) Static Stores G11C 11/412 (20130101) G11C 11/417 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11269683 | Kutzke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Demetrious Kutzke (Panama City, Florida); Matthew Bays (Panama City, Florida) |
| ABSTRACT | Methods and systems are provided for schedule deconfliction to enhance cooperation among heterogeneous teams of autonomous agents in situations where communication is severely limited. A dynamic scheduling framework, referred to herein as the Generous Agent Algorithm (GAA), organically deconflicts redundant service tasks as agents from distinct teams come into conflict and discover one another. Individual agents within a localized area can communicate their schedules to one another. Using the GAA, the agents propose modified schedules, vacating their most costly task from their schedules, while simultaneously augmenting their schedules with another agent's vacated task. The action taken by an agent does not increase an agent's makespan beyond the time set by that agent's team. Thus, the methods and systems, ensure that schedule alterations are done without degrading a team's global makespan. |
| FILED | Monday, July 27, 2020 |
| APPL NO | 16/940134 |
| ART UNIT | 2196 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/48 (20130101) G06F 9/50 (20130101) G06F 9/52 (20130101) G06F 9/485 (20130101) G06F 9/3836 (20130101) G06F 9/4806 (20130101) G06F 9/4843 (20130101) G06F 9/4856 (20130101) G06F 9/4875 (20130101) G06F 9/4881 (20130101) Original (OR) Class G06F 9/4893 (20130101) G06F 9/5005 (20130101) G06F 9/5011 (20130101) G06F 9/5022 (20130101) G06F 9/5027 (20130101) G06F 9/5044 (20130101) G06F 9/5061 (20130101) G06F 9/5072 (20130101) G06F 9/5083 (20130101) G06F 9/5088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11270105 | Ashek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Mahmood Saajan Ashek (Markham, Canada); Raghu Kiran Ganti (White Plains, New York); Shreeranjani Srirangamsridharan (White Plains, New York); Mudhakar Srivatsa (White Plains, New York); Asif Sharif (Milton, Canada); Ramey Ghabros (Toronto, Canada); Somesh Jha (Toronto, Canada); Mojdeh Sayari Nejad (North York, Canada); Mohammad Siddiqui (Toronto, Canada); Yusuf Mai (Richmond Hill, Canada) |
| ABSTRACT | A method and system for extracting information from a drawing. The method includes classifying nodes in the drawing, extracting attributes from the nodes, determining whether there are errors in the node attributes, and removing the nodes from the drawing. The method also includes identifying edges in the drawing, extracting attributes from the edges, and determining whether there are errors in the edge attributes. The system includes at least one processing component, at least one memory component, an identification component, an extraction component, and a correction component. The identification component is configured to classify nodes in the drawing, remove the nodes from the drawing, and identify edges in the drawing. The extraction component is configured to extract attributes from the nodes and edges. The correction component is configured to determine whether there are errors in the extracted attributes. |
| FILED | Tuesday, September 24, 2019 |
| APPL NO | 16/580229 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/03 (20130101) G06K 9/00456 (20130101) G06K 9/00463 (20130101) G06K 9/00476 (20130101) Original (OR) Class G06K 9/4604 (20130101) G06K 2209/01 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Image Data Processing or Generation, in General G06T 7/13 (20170101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11270192 | Friedman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Daniel J. Friedman (Sleepy Hollow, New York); Seongwon Kim (Old Tappan, New Jersey); Chung H. Lam (Peekskill, New York); Dharmendra S. Modha (San Jose, California); Bipin Rajendran (White Plains, New York); Jose A. Tierno (Palo Alto, California) |
| ABSTRACT | One embodiment relates to a neuromorphic network including electronic neurons and an interconnect circuit for interconnecting the neurons. The interconnect circuit includes synaptic devices for interconnecting the neurons via axon paths, dendrite paths and membrane paths. Each synaptic device includes a variable state resistor and a transistor device with a gate terminal, a source terminal and a drain terminal, wherein the drain terminal is connected in series with a first terminal of the variable state resistor. The source terminal of the transistor device is connected to an axon path, the gate terminal of the transistor device is connected to a membrane path and a second terminal of the variable state resistor is connected to a dendrite path, such that each synaptic device is coupled between a first axon path and a first dendrite path, and between a first membrane path and said first dendrite path. |
| FILED | Friday, March 09, 2018 |
| APPL NO | 15/917414 |
| ART UNIT | 2127 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/06 (20130101) Original (OR) Class G06N 3/08 (20130101) G06N 3/049 (20130101) G06N 3/063 (20130101) G06N 3/0635 (20130101) Static Stores G11C 11/54 (20130101) G11C 13/0004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11270196 | Sawada et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Jun Sawada (Austin, Texas); Filipp A. Akopyan (New Windsor, New York); Rathinakumar Appuswamy (San Jose, California); John V. Arthur (Mountain View, California); Andrew S. Cassidy (San Jose, California); Pallab Datta (San Jose, California); Steven K. Esser (San Jose, California); Myron D. Flickner (San Jose, California); Dharmendra S. Modha (San Jose, California); Tapan K. Nayak (San Jose, California); Carlos O. Otero (San Jose, California) |
| ABSTRACT | Neural inference chips for computing neural activations are provided. In various embodiments, the neural inference chip is adapted to: receive an input activation tensor comprising a plurality of input activations; receive a weight tensor comprising a plurality of weights; Booth recode each of the plurality of weights into a plurality of Booth-coded weights, each Booth coded value having an order; multiply the input activation tensor by the Booth coded weights, yielding a plurality of results for each input activation, each of the plurality of results corresponding to the orders of the Booth-coded weights; for each order of the Booth-coded weights, sum the corresponding results, yielding a plurality of partial sums, one for each order; and compute a neural activation from a sum of the plurality of partial sums. |
| FILED | Tuesday, October 15, 2019 |
| APPL NO | 16/653366 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/063 (20130101) Original (OR) Class G06N 3/0481 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11270197 | Shao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NVIDIA Corp. (Santa Clara, California) |
| ASSIGNEE(S) | NVIDIA Corp. (Santa Clara, California) |
| INVENTOR(S) | Yakun Shao (Santa Clara, California); Rangharajan Venkatesan (San Jose, California); Miaorong Wang (San Jose, California); Daniel Smith (Los Gatos, California); William James Dally (Incline Village, Nevada); Joel Emer (Acton, Massachusetts); Stephen W. Keckler (Austin, Texas); Brucek Khailany (Austin, Texas) |
| ABSTRACT | A distributed deep neural net (DNN) utilizing a distributed, tile-based architecture includes multiple chips, each with a central processing element, a global memory buffer, and a plurality of additional processing elements. Each additional processing element includes a weight buffer, an activation buffer, and vector multiply-accumulate units to combine, in parallel, the weight values and the activation values using stationary data flows. |
| FILED | Monday, November 04, 2019 |
| APPL NO | 16/672918 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3877 (20130101) G06F 17/16 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/063 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11270411 | Garrido et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Austin F. Garrido (Northridge, California); Shankar R. Rao (Agoura Hills, California); Jose Cruz-Albrecht (Oak Park, California); Timothy J. Derosier (Colorado, Colorado) |
| ABSTRACT | A system for real time bilinear interpolation includes a bilinear interpolation module capable of: generating pixel addresses for original image pixels of an original image needed for performing bilinear interpolation of the original image to form a resized image, wherein the generated pixel addresses assume all the original image pixels of the original image are accessible, and performing bilinear interpolation, and a pixel smart memory module capable: of sequentially receiving original image pixel rows of the original image an original image pixel row a time, predicting which original image pixel rows are needed for performing bilinear interpolation, storing only the needed sequentially received original image pixel rows in a memory, decoding the generated pixel addresses to form decoded addresses to access the needed original image pixel rows stored in the memory, and sending the needed original image pixel rows to the bilinear interpolation module for performing bilinear interpolation. |
| FILED | Friday, March 29, 2019 |
| APPL NO | 16/369779 |
| ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 1/324 (20130101) Image Data Processing or Generation, in General G06T 1/60 (20130101) G06T 3/4007 (20130101) Original (OR) Class G06T 3/4023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11270451 | Peli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Schepens Eye Research Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Schepens Eye Research Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Eliezer Peli (Boston, Massachusetts); JaeHyun Jung (Winchester, Massachusetts); Cheng Qiu (Medford, Massachusetts) |
| ABSTRACT | A system for providing information about an environment to a user within the environment is featured. An electronic processor is configured to receive input including a user selection of an object of interest from among potential objects of interest. The electronic processor is further configured to provide output to guide the user to move the detection apparatus to position the object of interest near a reference point on a field of view of the detection apparatus, obtain multiple images of the object of interest during the user's movement of the detection apparatus, and crop each of the images to keep the object of interest near a reference point on each of the images. |
| FILED | Friday, March 16, 2018 |
| APPL NO | 16/498027 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/08 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00912 (20130101) G06K 9/3241 (20130101) Image Data Processing or Generation, in General G06T 7/593 (20170101) Original (OR) Class G06T 2200/04 (20130101) G06T 2207/10012 (20130101) G06T 2207/10028 (20130101) Pictorial Communication, e.g Television H04N 13/204 (20180501) H04N 13/271 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11270800 | Mitidis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aptima, Inc. (Woburn, Massachusetts) |
| ASSIGNEE(S) | Aptima, Inc. (Woburn, Massachusetts) |
| INVENTOR(S) | Andonis Mitidis (Rogers, Arkansas); Jeanine Ayers (Gibsonia, Pennsylvania) |
| ABSTRACT | Methods for selecting treatment paths are disclosed generally comprising the steps of: (a) discovering a set of treatment path clusters based on latent patterns in historical patient trace data, (b) building a set of binary classifiers based on historical patient trace data, historical patient data and target outcomes, and (c) given the treatment path clusters, actual patient data, and a selected target outcome, applying the binary classifiers to predict a treatment path for a new patient that optimizing the selected target outcome. Processor based systems to implement the methods are also disclosed. |
| FILED | Friday, November 09, 2018 |
| APPL NO | 16/186278 |
| ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4842 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) G16H 50/70 (20180101) Original (OR) Class G16H 80/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11270892 | Candler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Robert N. Candler (Los Angeles, California); Jimmy Chen-Yen Wu (Los Angeles, California); Ling Li (Los Angeles, California); Jere C. Harrison (Los Angeles, California) |
| ABSTRACT | A microfabrication process includes: (1) etching a shield pattern into a substrate; (2) forming a set of shielding layers on the substrate and in the shield pattern, wherein the shielding layers include n+1 magnetic layers and n spacing layers, n is 0 or an integer that is 1 or greater than 1, and each spacing layer is disposed between a pair of magnetic layers; and (3) planarizing the substrate to expose edges of the shielding layers. |
| FILED | Friday, February 01, 2019 |
| APPL NO | 16/264979 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/3213 (20130101) Original (OR) Class H01L 21/76898 (20130101) H01L 23/552 (20130101) H01L 43/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11270919 | Arvelo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Amilcar R. Arvelo (Poughkeepsie, New York); Michael J. Ellsworth (Lagrangeville, New York); Eric J. McKeever (Poughkeepsie, New York); Thong N. Nguyen (Poughkeepsie, New York); Edward J. Seminaro (Milton, New York) |
| ABSTRACT | A method of forming a custom module lid. The method may include placing a multichip module (MCM) between a module base and a temporary lid, target components are exposed through viewing windows in the temporary lid, a top surface of the target components is measured and mapped to create a target profile, the target profile is used to form custom pockets in a custom lid, and the custom pockets correspond to the target components. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 16/205315 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/4817 (20130101) H01L 23/04 (20130101) H01L 23/06 (20130101) H01L 23/42 (20130101) H01L 23/043 (20130101) Original (OR) Class H01L 23/3675 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 3/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11271124 | Dressick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Walter J. Dressick (Waldorf, Maryland); Jasbinder S. Sanghera (Ashburn, Virginia); Woohong Kim (Washington, District of Columbia); Colin C. Baker (Alexandria, Virginia); Jason D. Myers (Alexandria, Virginia); Jesse A. Frantz (Washington, District of Columbia) |
| ABSTRACT | A composition of matter having a coated silicon substrate with multiple alternating layers of polydopamine and polyallylamine bound copper-indium-gallium oxide (CIGO) nanoparticles on the substrate. A related composition of matter having polyallylamine bound to CIGO nanoparticles to form PAH-coated CIGO nanoparticles. A related CIGO thin film made via conversion of layer-by-layer assembled CIGO nanoparticles and polyelectrolytes. CIGO nanoparticles are created via a flame-spray pyrolysis method using metal nitrate precursors, subsequently coated with polyallylamine (PAH), and dispersed in aqueous solution. Multilayer films are assembled by alternately dipping a substrate into a solution of either polydopamine or polystyrenesulfonate and then in the CIGO-PAH dispersion to fabricate CIGO films as thick as 1-2 microns. |
| FILED | Wednesday, December 18, 2019 |
| APPL NO | 16/718575 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02565 (20130101) H01L 21/02568 (20130101) H01L 21/02601 (20130101) H01L 21/02614 (20130101) H01L 21/02628 (20130101) H01L 31/18 (20130101) H01L 31/0322 (20130101) Original (OR) Class H01L 31/0352 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/541 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11271131 | Shi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Zhisheng Shi (Norman, Oklahoma); Jijun Qiu (Norman, Oklahoma); Lance McDowell (Norman, Oklahoma) |
| ABSTRACT | A semiconductor PV detector comprises a Ge layer and a Pb-chalcogenide layer coupled to the Ge layer. The Ge layer comprises a first conduction band with a first conduction potential and a first valence band with a first valence potential. The Pb-chalcogenide layer comprises a second conduction band with a second conduction potential that is lower than the first conduction potential and a second valence band with a second valence potential that is lower than the first valence potential. The Ge layer and the Pb-chalcogenide layer form a heterojunction configured to allow electrons to flow from the Ge layer to the Pb-chalcogenide layer and allow holes to flow from the Pb-chalcogenide layer to the Ge layer. |
| FILED | Thursday, August 13, 2020 |
| APPL NO | 16/992855 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) H01L 31/105 (20130101) H01L 31/109 (20130101) Original (OR) Class H01L 31/0336 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11271193 | Ren et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Zhifeng Ren (Pearland, Texas); Shuo Chen (Houston, Texas); Fang Yu (Houston, Texas); Haiqing Zhou (Houston, Texas) |
| ABSTRACT | A method of manufacturing an electrode by disposing a three-dimensional substrate in a metal nitrate solution, drying, and thermally phosphatizing with a phosphorus source under inert gas to form a metal based phosphate catalyst on the substrate. An electrocatalyst and electrode produced via the method are also provided. |
| FILED | Monday, March 12, 2018 |
| APPL NO | 16/492319 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0428 (20130101) Original (OR) Class H01M 2004/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11271205 | |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ADA Technologies, Inc. (Littleton, Colorado) |
| ASSIGNEE(S) | ADA Technologies, Inc. (Littleton, Colorado) |
| INVENTOR(S) | Weibing Xing (Littleton, Colorado) |
| ABSTRACT | A composition containing a carbon monofluoride admixture is provided. The carbon monofluoride admixture is generally in the form of layer having opposing upper and lower surfaces. Usually, an ion conducting or a solid electrolyte layer is position on one of the upper or lower layers of the monofluoride admixture. In some configurations, the ion conducting or a solid electrolyte layer can be alkaline metal aluminum oxide or alkaline metal aluminum fluoride. The alkaline metal is commonly lithium, and the alkaline metal aluminum oxide or alkaline metal aluminum fluoride is more commonly MzAlXy (M is one of alkali metals, X=O, F), Z commonly can have a value from about 0.5 to about 10 and y can have a value from about 1.75 to about 6.5, more commonly z can have a value from about 1 to about 5 and y can have a value from about 2 to about 4. The carbon monofluoride admixture can include a polymeric binder and one or more of a conductive carbon black and conductive graphite. The carbon monofluoride admixture is generally a component one or more electrodes of an electrochemical energy storage device. |
| FILED | Thursday, January 09, 2020 |
| APPL NO | 16/738990 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/133 (20130101) H01M 4/366 (20130101) H01M 4/622 (20130101) H01M 4/625 (20130101) H01M 4/661 (20130101) H01M 4/662 (20130101) H01M 4/5835 (20130101) Original (OR) Class H01M 10/052 (20130101) H01M 10/056 (20130101) H01M 10/0525 (20130101) H01M 10/0562 (20130101) H01M 50/44 (20210101) H01M 50/431 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11271295 | Selvin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Skyler Selvin (San Jose, California); Walter S. Wall (Los Angeles, California); Geoffrey P. McKnight (Los Angeles, California) |
| ABSTRACT | The impedance of a loopstick antenna is directly modulated utilizing a mechanically actuated magnetoelastic material preferably placed in the core (or center) of looped wires forming the loopstick antenna. Using one or more mechanical actuators the permeability in the center of the loopstick antenna can be modulated at a rapid rate (such as with data or audio information), allowing the magnetic field outside of the antenna to be modulated at large bandwidths without requiring switches or modulators capable of high voltage thus reducing the overall complexity and cost of the transmitter. The external magnetic field is created by an AC source which is preferably impedance matched to the loopstick antenna by means of a matching network and is FM modulated according to a modulating signal applied to the one or more mechanical actuators. |
| FILED | Wednesday, April 24, 2019 |
| APPL NO | 16/393816 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/364 (20130101) Original (OR) Class H01Q 3/44 (20130101) Modulation H03C 7/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11271308 | Pelrine et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SRI INTERNATIONAL (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Ronald E. Pelrine (Longmont, Colorado); Annjoe Wong-Foy (Pacifica, California); Allen L. Hsu (Mountain View, California) |
| ABSTRACT | Systems are provided for the efficient generation of oscillating magnetic fields below the Low Frequency band. These systems generate such fields by mechanically rotating one or more diametrically-magnetized permanent magnets. In order to reduce friction, the magnets are rotated by applying a motive magnetic field to the magnet(s) to rotate the magnet(s) and thereby generate the oscillating magnetic field. Additionally, diamagnetic repulsion, active magnetic field control, and/or biasing permanent magnets are employed to levitate the rotating magnet(s), further reducing friction and increasing system efficiency. These systems may be employed to generate modulated low-frequency oscillating magnetic fields for communication through seawater, rocks, or other obstacles. Additionally or alternatively, these systems may be employed to generate low-frequency oscillating magnetic fields for navigation and location sensing, resource identification and extraction, or other applications. |
| FILED | Wednesday, September 05, 2018 |
| APPL NO | 16/122650 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/36 (20130101) H01Q 3/04 (20130101) H01Q 7/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11271358 | Reeves-Hall |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Peter C Reeves-Hall (Northbridge, Massachusetts) |
| ABSTRACT | In a draw tower for producing a length of optical fiber, a preform feed accepts a preform into the draw tower and a furnace downstream of the preform feed heats the preform. Fiber shaping hardware downstream of the thermal furnace is controlled by fiber shaping control electronics to produce along the fiber at least one low-absorption fiber section having a first cross-sectional geometry of the inner cladding layer corresponding to a first level of absorption of input pump light from the inner cladding layer to the core and at least one high-absorption fiber section having a second cross-sectional geometry of the inner cladding layer corresponding to a second level of absorption of input pump light from the inner cladding layer to the core that is greater than the first level of absorption. A tractor downstream of shaping hardware pulls the preform through the furnace and shaping hardware. |
| FILED | Thursday, June 18, 2020 |
| APPL NO | 16/904935 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/06754 (20130101) H01S 3/10013 (20190801) Original (OR) Class H01S 3/13017 (20190801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11271533 | Narla et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Anirudh Narla (New Haven, Connecticut); Katrina Sliwa (New Haven, Connecticut); Michael Hatridge (New Haven, Connecticut); Shyam Shankar (New Haven, Connecticut); Luigi Frunzio (North Haven, Connecticut); Robert J. Schoelkopf, III (Madison, Connecticut); Michel Devoret (New Haven, Connecticut) |
| ABSTRACT | A wireless Josephson-junction-based amplifier is described that provides improved tunability and increased control over both a quality factor Q and participation ratio p of the amplifier. The device may be fabricated on a chip and mounted in a waveguide. No wire bonding between the amplifier and coaxial cables or a printed circuit board is needed. At least one antenna on the chip may be used to couple energy between the waveguide and wireless JBA. The amplifier is capable of gains greater than 25 dB. |
| FILED | Wednesday, March 07, 2018 |
| APPL NO | 15/914995 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Amplifiers H03F 19/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11271759 | Cambou |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Northern Arizona University (Flagstaff, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY (Flagstaff, Arizona) |
| INVENTOR(S) | Bertrand F Cambou (Flagstaff, Arizona) |
| ABSTRACT | Systems and methods for securing blockchain and other cryptographically signed ledgers are disclosed. Client devices with arrays of physical-unclonable-function devices are respond to challenges from a server. Characteristics of the arrays are stored by the server during a secure enrollment process. Subsequently, the server issues challenges to the clients and receives responses generated by the clients from characteristics of portions of the arrays specified by the challenges. The challenge responses are used to authenticate the clients and are also used as cryptographic private keys for signing transaction blocks. Public keys corresponding to the private keys are generated allowing signed transaction blocks to be validated as well as allowing clients originating the transactions to be authenticated by other clients. Ternary PUF characterization schemes are used to achieve acceptable authentication error rates. |
| FILED | Wednesday, September 04, 2019 |
| APPL NO | 16/560502 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 7/588 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/12 (20130101) H04L 9/0643 (20130101) H04L 9/0844 (20130101) H04L 9/3278 (20130101) Original (OR) Class H04L 2209/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11266616 | Kern et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| ASSIGNEE(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| INVENTOR(S) | Dorothee Kern (Waltham, Massachusetts); Adelajda Zorba (Waltham, Massachusetts) |
| ABSTRACT | The present invention features therapeutic compositions comprising an agent that specifically binds to a PIF pocket of Aurora A kinase and an agent that specifically binds to an ATP-binding site of Aurora A kinase, and the use of the therapeutic compositions to modulate Aurora A kinase for the treatment of cancer. |
| FILED | Wednesday, February 08, 2017 |
| APPL NO | 16/075550 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/192 (20130101) Original (OR) Class A61K 31/192 (20130101) A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/517 (20130101) A61K 31/517 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/40 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2500/04 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/00 (20190201) G16B 15/30 (20190201) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/50 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266947 | Malhotra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Deepika Malhotra (Richland, Washington); Phillip K. Koech (Richland, Washington); David J. Heldebrant (Richland, Washington); Vassiliki-Alexandra Glezakou (Richland, Washington); Roger J. Rousseau (Richland, Washington); Manh Thuong Nguyen (Richland, Washington); Robert Perry (Richland, Washington); Jordan P. Page (Richland, Washington); David C. Cantu (Richland, Washington) |
| ABSTRACT | Disclosed herein is a method and system for CO2 removal from a gas stream using a diamine solvent having a Formula I R1(R2)N-L1-NH-R3 (I) With respect to Formula I, each of R1 and R2 independently is aliphatic, cycloaliphatic, or R1 and R2 together with the nitrogen to which they are attached, form a heterocyclyl ring; L1 is aliphatic, cycloaliphatic, or L1 and R1 together with the nitrogen to which they are attached form a heterocyclyl ring; and R3 is aliphatic, cycloaliphatic, cycloalkylalkyl, or alkoxyalkyl. And/or the compound may have a viscosity of less than 75 cP at a CO2-loading of 40 mol % and at a temperature of 40° C. |
| FILED | Monday, March 25, 2019 |
| APPL NO | 16/363672 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/1425 (20130101) B01D 53/1475 (20130101) B01D 53/1493 (20130101) Original (OR) Class B01D 2252/2041 (20130101) B01D 2252/20426 (20130101) B01D 2252/20431 (20130101) B01D 2252/20452 (20130101) Heterocyclic Compounds C07D 295/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266975 | DeGrado et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Timothy R. DeGrado (Rochester, Minnesota); Mukesh K. Pandey (Rochester, Minnesota); John Byrne (Boston, Massachusetts) |
| ABSTRACT | Methods of producing and isolating 68Ga, 89Zr, 64Cu, 63Zn, 86Y, 61Cu, 99mTc, 45Ti, 13N, 52Mn, or 44Sc and solution targets for use in the methods are disclosed. The methods of producing 68Ga, 89Zr, 64Cu, 63Zn, 86Y, 61Cu, 99mTc, 45Ti, 13N, 52Mn, or 44Sc include irradiating a closed target system with a proton beam. The system can include a solution target. The methods of producing isolated 68Ga, 89Zr, 64Cu, 63Zn, 86Y, 61Cu, 99mTc, 45Ti, 52Mn, or 44Sc further include isolating 68Ga, 89Zr, 64Cu, 63Zn, 86Y, 61Cu, 99mTc, 45Ti, 52Mn, or 44Sc by ion exchange chromatography. An example target includes a target body including a target cavity for receiving the target material; a housing defining a passageway for directing a particle beam at the target cavity; a target window for covering an opening of the target cavity; and a coolant gas flow path disposed in the passageway upstream of the target window. |
| FILED | Monday, September 09, 2019 |
| APPL NO | 16/565125 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 15/08 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/22 (20130101) Original (OR) Class B01J 20/3085 (20130101) B01J 20/3092 (20130101) B01J 20/3251 (20130101) Conversion of Chemical Elements; Radioactive Sources G21G 1/001 (20130101) G21G 1/10 (20130101) G21G 2001/0021 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 6/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267201 | Kunc et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee); Magnum Venus Products, Inc. (Knoxville, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Vlastimil Kunc (Knoxville, Tennessee); Ahmed A. Hassen (Knoxville, Tennessee); Brian K. Post (Knoxville, Tennessee); David W. Nuttall (Knoxville, Tennessee); John M. Lindahl (Powell, Tennessee); Lonnie J. Love (Knoxville, Tennessee); Tim Deluca (Lake Tapps, Washington); Mike Walch (Port Orchard, Washington); Benjamin J. Hedger (Knoxville, Tennessee) |
| ABSTRACT | An assembly for additive manufacturing includes a build housing including a base, a print head, and a print head support connected to the base for supporting the print head above the base. A driver system is provided for moving the print head and the base relative to one another. A build platform comprising a build support and at least one platen. The build support can be detachably engageable to the housing. The platens can be detachably engageable to the build support. The build support can include registration structure for registering the position of the build support relative to the build housing. A method of additive manufacturing is also disclosed. |
| FILED | Thursday, March 12, 2020 |
| APPL NO | 16/816982 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/245 (20170801) Original (OR) Class B29C 64/379 (20170801) B29C 64/393 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2101/10 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 40/20 (20200101) B33Y 50/02 (20141201) B33Y 70/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267702 | Stavila et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Vitalie Stavila (Pleasanton, California); James Lawrence White (Fremont, California) |
| ABSTRACT | A method for obtaining solid-state metal borohydrides without toxic precursors and expensive solvents includes dry mixing of metal hydrides and metal polyhydro-closo-borate starting materials. High pressure and heating is also used in the method. These materials can be used for hydrogen storage, general reducing agents, organic synthesis, wastewater treatment, and paper pulp bleaching. |
| FILED | Tuesday, June 05, 2018 |
| APPL NO | 16/000683 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 6/21 (20130101) Original (OR) Class C01B 35/026 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267838 | Hegg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| INVENTOR(S) | Eric Linke Hegg (East Lansing, Michigan); James E. Jackson (Haslett, Michigan); Grace Elizabeth Klinger (Lansing, Michigan) |
| ABSTRACT | The disclosure relates to a method for depolymerizing lignin. The method includes reacting a lignin compound with a thiol compound to depolymerize the lignin compound and to form a depolymerized lignin product having a reduced molecular weight relative to the lignin compound prior to reacting. The method can further include forming an oxidized thiol reaction product between two thiol groups from one or more thiol compounds, and then reducing the oxidized thiol reaction product to re-form or regenerate the thiol compound for further lignin depolymerization. |
| FILED | Tuesday, April 17, 2018 |
| APPL NO | 16/603328 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 37/54 (20130101) C07C 41/01 (20130101) C07C 45/65 (20130101) Compounds of Unknown Constitution C07G 1/00 (20130101) Original (OR) Class Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/25 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267855 | Thallapuranam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| INVENTOR(S) | Suresh Kumar Thallapuranam (Fayetteville, Arkansas); Shilpi Agarwal (Fayetteville, Arkansas); Ravi Kumar Gundampati (Fayetteville, Arkansas); Srinivas Jayanthi (Fayetteville, Arkansas); Tengjiao Wang (Fayetteville, Arkansas); Jake Jones (Fayetteville, Arkansas); Olivia Kolenc (Fayetteville, Arkansas); Ngoc Lam (Fayetteville, Arkansas); Isabelle Niyonshuti (Fayetteville, Arkansas); Kartik Balachandran (Fayetteville, Arkansas); Kyle Quinn (Fayetteville, Arkansas); Jingyi Chen (Fayetteville, Arkansas) |
| ABSTRACT | Engineered FGF1 and FGF2 polypeptides, polynucleotides encoding these polypeptides and DNA constructs, vectors and compositions including these engineered polypeptides are provided herein. The engineered FGF1 and FGF2 polypeptides are more stable than their wild-type counterparts and may be more effective at treating a variety of conditions that FGF1 and FGF2 are useful for treating such as wound healing. |
| FILED | Monday, March 18, 2019 |
| APPL NO | 16/356872 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 38/00 (20130101) A61K 38/1825 (20130101) Peptides C07K 14/501 (20130101) Original (OR) Class C07K 14/503 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267920 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Matthew N. Lee (Los Alamos, New Mexico); Nicholas G. Parra-Vasquez (Los Alamos, New Mexico); Kyle J. Cluff (Los Alamos, New Mexico) |
| ABSTRACT | Disclosed herein are embodiments of a printable composition that can be used to make printed products of a chosen material chemistry that have different levels of porosity within the printed product's structure Also disclosed herein are embodiments of a printed product that has multiple levels of porosity throughout its structure, which can include a macroscale level of porosity, a microscale level of porosity, a nanoscale level of porosity and any combination thereof. These printed products can be made using a 3-D printer and can be made from a single printable composition without the need to add different structural components during the production process. Also disclosed herein are embodiments of a method for making and using a printed product. |
| FILED | Friday, February 01, 2019 |
| APPL NO | 16/265641 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/00 (20210101) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/124 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 222/20 (20130101) Original (OR) Class C08F 222/102 (20200201) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 4/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268034 | Chauhan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | Battelle Memorial Institute (Columbus, Ohio) |
| INVENTOR(S) | Satya P. Chauhan (Columbus, Ohio); Daniel B. Garbark (Blacklick, Ohio) |
| ABSTRACT | A process of producing a distillate fuel from lignin includes: preparing a biomass-derived lignin solvent; dissolving the lignin in the biomass-derived solvent; and separating undissolved lignin and mineral matter to produce a syncrude. In certain embodiments, the process further includes subjecting the syncrude to a hydrotreatment/hydrogenation process to produce a distillate fuel. A process to improve direct lignin liquefaction includes: using a non-hydrogenated lipid in a direct lignin liquefaction process to facilitate lignin depolymerization. A process for using a biomass-derived feedstock as a hydrogen donor includes: providing a biomass-derived feedstock; modifying the feedstock to improve its usefulness as a hydrogen donor; and conducting a transfer hydrogenation process using the modified feedstock as a hydrogen donor. |
| FILED | Friday, July 13, 2018 |
| APPL NO | 16/631116 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 1/002 (20130101) C10G 1/02 (20130101) C10G 1/042 (20130101) C10G 1/045 (20130101) C10G 1/065 (20130101) Original (OR) Class C10G 45/32 (20130101) C10G 45/44 (20130101) C10G 69/06 (20130101) C10G 2300/42 (20130101) C10G 2300/44 (20130101) C10G 2300/107 (20130101) C10G 2300/1011 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 30/20 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268706 | Colon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Carlos J. Colon (Rockledge, Florida); Danny S. Parker (Cocoa Beach, Florida) |
| ABSTRACT | A solar power system has a photovoltaic module that supplies electrical current derived from sunlight to a heater system of a hot water tank. The heater system uses the electrical energy from the photovoltaic module, and optionally also from a local power grid, to heat water up to a selected maximum stored hot water temperature. Control circuitry senses when the level of electrical power is below a threshold solar-power level, and in response sets the stored hot water temperature for the heater system to a first lower temperature value. The control circuitry also senses when the level of electrical power is above the threshold solar-power level, an in response sets the stored hot water temperature for the heater system to a second elevated temperature value higher than the lower temperature, making advantageous use of solar power when available. A mixing unit adds cold water to set the dispensed water temperature. |
| FILED | Friday, December 21, 2018 |
| APPL NO | 16/231318 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Domestic- or Space-heating Systems, e.g Central Heating Systems; Domestic Hot-water Supply Systems; Elements or Components Therefor F24D 11/0221 (20130101) F24D 17/0021 (20130101) Original (OR) Class F24D 2200/14 (20130101) F24D 2200/123 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268738 | Bahar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xergy Inc. (Harrington, Delaware) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bamdad Bahar (Georgetown, Delaware); William Parmelee (Seaford, Delaware) |
| ABSTRACT | An electrochemical heat transfer device for a hot water tank utilizes an electrochemical hydrogen compressor to pump hydrogen into and out of a tank having a metal hydride forming alloy therein. The absorption of hydrogen by the metal hydride forming alloy is exothermic, produces heat, and the desorption of the hydrogen from the metal hydride forming alloy is endothermic and draws heat in. An electrochemical hydrogen compressor may be configured between to tanks and pump hydrogen back and forth to form a heat transfer device, such as a hot water heater. A heat transfer device may be coupled with the tank or may comprise the outer surface of the tank to transfer heat to an object or to the surroundings. A closed loop may be configured having two tanks and one or two electrochemical hydrogen compressors to pump the hydrogen in a loop around the system. |
| FILED | Tuesday, January 22, 2019 |
| APPL NO | 16/254427 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/16 (20130101) Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 5/0014 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 17/12 (20130101) F25B 30/04 (20130101) Original (OR) Class F25B 35/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268896 | Gattu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Vineeth Kumar Gattu (Chicago, Illinois); William L. Ebert (Batavia, Illinois) |
| ABSTRACT | A method for predicting corrosion rates of a material during service conditions is provided, the method having the steps of determining a first phase composition of the material; exposing the material to service conditions chemical environment; applying an electrical potential to the exposed material to represent the solution redox; identifying ranges of the applied potential that correspond to different corrosion behaviors of the material; quantifying current and surface electrical properties during corrosion; and determining a second phase composition of the material to identify corroded phases. Also provided is a method for determining radionuclide source terms, the method having the steps of supplying a multiphase metallic waste containing the radionuclides; immersing the waste in a solution representing repository chemistry conditions; and oxidizing the immersed waste for a period of time and at particular imposed voltages representing solution redox values to establish a steady current representing corrosion rate of the waste. |
| FILED | Thursday, March 14, 2019 |
| APPL NO | 16/353695 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 13/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 17/02 (20130101) Original (OR) Class G01N 17/006 (20130101) G01N 27/026 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 5/125 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268984 | Sun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Department of Energy (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Chenhu Sun (South Park, Pennsylvania); Ping Lu (Sewickley, Pennsylvania); Ruishu Wright (Pittsburgh, Pennsylvania); Paul R Ohodnicki (Allison Prk, Pennsylvania) |
| ABSTRACT | A system and method for forming a low cost optical sensor array. The sensor includes an optical fiber; a first nanocomposite thin film along at least a portion of the optical fiber for interrogating a first parameter through a correlated signal having a first wavelength; and a second nanocomposite thin film along at least a portion of the optical fiber for interrogating a second parameter through a correlated signal having a second wavelength different from the wavelength of the first parameter. |
| FILED | Wednesday, April 17, 2019 |
| APPL NO | 16/387359 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/35338 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 1/07 (20130101) Original (OR) Class G01R 31/62 (20200101) Optical Elements, Systems, or Apparatus G02B 6/4206 (20130101) G02B 6/4298 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11269137 | Kiani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Leily S. Kiani (Napa, California); Jay W. Dawson (Livermore, California); Derrek R. Drachenberg (Livermore, California); Michael J. Messerly (Danville, California); Paul H. Pax (Livermore, California) |
| ABSTRACT | A non-radial array of microstructure elements provides enhanced wavelength selective filtering. The elements are arranged along a line that does not intersect the center of the core. In this configuration, the first coupling element in an array that is nearest to the core is a non-integer array unit spacing from the main waveguide where the array unit spacing is defined as the flat to flat distance of a hexagonal cell. |
| FILED | Friday, May 29, 2020 |
| APPL NO | 16/887313 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/02052 (20130101) G02B 6/02371 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11269687 | Jacob et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Philip Jacob (Congers, New York); Philip Neil Strenski (Yorktown Heights, New York); Charles Johns (Austin, Texas) |
| ABSTRACT | A system and method for supporting data MapReduce operations in a tuple space/coordinated namespace (CNS) extended memory storage architecture. The system-wide CNS provides an efficient means for storing and communicating data generated by local processes running at the nodes, and coordinated to provide MapReduce operations in a multi-nodal system. A hardware accelerated mechanism supports map reduce sorting/shuffle operations and reduce operations according to an aggregate function. Local processes running at a node generate a tuple corresponding to data generated by a process, each tuple having a tuple name and tuple data value corresponding to the generated data. Each tuple is processed and stored at the node or another node, dependent upon its tuple name. Tuple records associated with a tuple name are accumulated at one or more nodes according to a linked list structure at each that is accessible via a hash table index pointer at the node. |
| FILED | Tuesday, June 11, 2019 |
| APPL NO | 16/437320 |
| ART UNIT | 2163 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4881 (20130101) G06F 9/5016 (20130101) G06F 9/5044 (20130101) Original (OR) Class G06F 16/2255 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11270525 | Moniot et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Matthew Louis Moniot (Golden, Colorado); Yi Hou (Highlands Ranch, Colorado) |
| ABSTRACT | Described herein are systems and methods for detecting the number of occupants in a vehicle. The detecting may be performed using a camera and a processing device. The detecting may be anonymous and the image of the interior of the vehicle is not stored on the processing device. |
| FILED | Wednesday, November 06, 2019 |
| APPL NO | 16/675403 |
| ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6256 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11270600 | West et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Department of Energy (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES DEPARTMENT OF ENERGY (Washington, District of Columbia) |
| INVENTOR(S) | Shawn M. West (West Mifflin, Pennsylvania); Matthew R. Chilleo (North Huntingdon, Pennsylvania); William T. Portser (Jeannette, Pennsylvania) |
| ABSTRACT | Disclosed are systems and methods for simulating proximity detection of physical effects, the system including an external probe; a base unit associated with the external probe via a connector, the base unit comprising at least one processor coupled to the connector, the at least one processor configured to compute results based on an input received from the external probe; an input device; and a graphical display unit configured to display at least one of the computed results from the at least one processor and the input received from the input device and input received from the external probe. |
| FILED | Monday, May 14, 2018 |
| APPL NO | 15/978299 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 1/06788 (20130101) Measurement of Nuclear or X-radiation G01T 1/00 (20130101) G01T 1/20 (20130101) G01T 1/169 (20130101) Analogue Computers G06G 7/54 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 9/00 (20130101) Original (OR) Class G09B 23/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11270802 | Reid |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Robert Stowers Reid (Santa Fe, New Mexico) |
| ABSTRACT | Technique(s) to mitigate creep and/or cascade failure in high temperature heat pipe reactor cores may include gas loading each heat pipe such that when one or more heat pipes in the heat pipe array fail, the adjacent heat pipes can accommodate added heat load with little change in temperature. |
| FILED | Friday, November 09, 2018 |
| APPL NO | 16/186090 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/06 (20130101) F28D 15/0275 (20130101) F28D 2021/0054 (20130101) Nuclear Reactors G21C 15/18 (20130101) G21C 15/257 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11270850 | Brambilla |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FastCAP SYSTEMS Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | FASTCAP SYSTEMS CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Nicolò Michele Brambilla (Boston, Massachusetts) |
| ABSTRACT | An electric double layer capacitor (EDLC) is disclosed including: a first electrode including a first current collector and first plurality of carbon nanotubes (CNTs) disposed substantially directly upon the first current collector; a second electrode comprising a second current collector and second plurality of CNTs disposed substantially directly upon the second current collector; and an electrolyte disposed between and in contact with (e.g., wetting) the first and second electrodes. In some embodiments, the EDLC is configured to have a capacitive frequency window comprising about 1 Hz to about 50 Hz. |
| FILED | Sunday, June 19, 2016 |
| APPL NO | 15/186534 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/28 (20130101) H01G 11/36 (20130101) H01G 11/52 (20130101) H01G 11/56 (20130101) H01G 11/60 (20130101) H01G 11/62 (20130101) H01G 11/64 (20130101) H01G 11/68 (20130101) Original (OR) Class H01G 11/70 (20130101) H01G 11/80 (20130101) H01G 11/86 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/1807 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11271123 | Karunadasa et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Hemamala Indivari Karunadasa (Palo Alto, California); Adam H. Slavney (Mountain View, California) |
| ABSTRACT | An alloyed halide double perovskite material, an alloyed halide double perovskite solar-cell absorber and solar cells constructed with such absorbers, the alloyed halide double perovskite material having the formula A2B1-aB′1-bDxX6, where A is an inorganic cation, an organic cation, a mixture of inorganic cations, a mixture of organic cations, or a mixture of one or more inorganic cations and one or more organic cations, where B is a metal, a mixture of metals, a metalloid, a mixture of metalloids, any mixture thereof, or is a vacancy, where B′ is a metal, a mixture of metals, a metalloid, a mixture of metalloids, any mixture thereof, or is a vacancy, where D is a dopant, and where X is a halide, a pseudohalide, a mixture of halides, a mixture of pseudohalides, or a mixture of halides and pseudohalides, and where x=a+b. |
| FILED | Tuesday, March 27, 2018 |
| APPL NO | 15/937530 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 19/002 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/94 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/072 (20130101) H01L 31/0321 (20130101) Original (OR) Class H01L 31/0549 (20141201) H01L 51/005 (20130101) H01L 51/009 (20130101) H01L 51/42 (20130101) H01L 51/0077 (20130101) H01L 51/0079 (20130101) H01L 51/0091 (20130101) H01L 51/447 (20130101) H01L 51/4253 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11271180 | Hammond et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SolarWindow Technologies, Inc. (Scottsdale, Arizona); Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); SolarWindow Technologies, Inc. (Scottsdale, Arizona) |
| INVENTOR(S) | Scott R. Hammond (Seattle, Washington); Marinus Franciscus Antonius Maria van Hest (Lakewood, Colorado); John A. Conklin (Apalachin, New York) |
| ABSTRACT | Visually undistorted thin film electronic devices are provided. In one embodiment, a method for producing a thin-film electronic device comprises: opening a scribe in a stack of thin film material layers deposited on a substrate to define an active region and an inactive region of the thin-film electronic device, the stack comprising at least one active semiconductor layer. The active region comprises a non-scribed area of the stack and the inactive region comprises a region of the stack where thin film material was removed by the scribe. The method further comprises depositing at least one scribe fill material into a gap opened by the scribe. The scribe fill material has embedded therein one or more coloring elements that alter an optical characteristics spectrum of the inactive region to obtain an optical characteristics spectrum of the active region within a minimum perceptible difference for an industry defined standard observer. |
| FILED | Thursday, May 16, 2019 |
| APPL NO | 16/414492 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/301 (20130101) H01L 31/0465 (20141201) H01L 51/0001 (20130101) H01L 51/44 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11271193 | Ren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Zhifeng Ren (Pearland, Texas); Shuo Chen (Houston, Texas); Fang Yu (Houston, Texas); Haiqing Zhou (Houston, Texas) |
| ABSTRACT | A method of manufacturing an electrode by disposing a three-dimensional substrate in a metal nitrate solution, drying, and thermally phosphatizing with a phosphorus source under inert gas to form a metal based phosphate catalyst on the substrate. An electrocatalyst and electrode produced via the method are also provided. |
| FILED | Monday, March 12, 2018 |
| APPL NO | 16/492319 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0428 (20130101) Original (OR) Class H01M 2004/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11271214 — Three-dimensional ion transport networks and current collectors for electrochemical cells
| US 11271214 | Roumi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Farshid Roumi (Pasadena, California); Mahshid Roumi (Pasadena, California) |
| ABSTRACT | Provided herein are three-dimensional ion transport networks and current collectors for electrodes of electrochemical cells. Exemplary electrodes include interconnected layers and channels including an electrolyte to facilitate ion transport. Exemplary electrodes also include three dimensional current collectors, such as current collectors having electronically conducting rods, electronically conducting layers or a combination thereof. |
| FILED | Tuesday, April 02, 2019 |
| APPL NO | 16/373308 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/78 (20130101) Original (OR) Class H01M 4/80 (20130101) H01M 4/366 (20130101) H01M 4/742 (20130101) H01M 10/054 (20130101) H01M 10/0525 (20130101) H01M 10/0565 (20130101) H01M 12/08 (20130101) H01M 50/409 (20210101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11271226 | Saraidaridis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Technologies Corporation (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Waltham, Massachusetts) |
| INVENTOR(S) | James D. Saraidaridis (Hartford, Connecticut); Michael L. Perry (Groton, Connecticut); Robert Mason Darling (South Windsor, Connecticut) |
| ABSTRACT | A method for a redox flow battery includes using a cell of a redox flow battery to store electrical energy and discharge the stored electrical energy. The using includes circulating a first electrolyte solution through a first circulation loop in fluid connection with the first electrode of the cell; circulating a second electrolyte solution through a second circulation loop in fluid connection with the second electrode of the cell; and at least one of a first element from the first electrolyte solution in the first electrode permeates through the separator layer and precipitates as a first solid product in the second electrode and a second element from the second electrolyte solution permeates through the separator layer and precipitates a second solid product in the first electrode. The method also includes removing at least a portion of the first solid product or the second solid product from the first electrode and the second electrode, respectively. |
| FILED | Friday, December 11, 2020 |
| APPL NO | 17/119427 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/08 (20130101) H01M 8/188 (20130101) H01M 8/04186 (20130101) Original (OR) Class H01M 8/04201 (20130101) H01M 2300/0002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11271237 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Lu Zhang (Lisle, Illinois); Jingjing Zhang (Downers Grove, Illinois); Ilya A. Shkrob (Chicago, Illinois) |
| ABSTRACT | The present invention provides a redox flow battery comprising a negative electrode (also referred to herein as an “anode”) immersed in a first liquid electrolyte (also referred to herein as a “negative electrolyte” or “anolyte”), a positive electrode (also referred to herein as a “cathode”) immersed in a second liquid electrolyte (also referred to herein as a “positive electrolyte” or “catholyte”), and a cation-permeable separator (e.g., a membrane or other cation-permeable material) partitioning the negative electrode/anolyte from the positive electrode/catholyte. The redox reactant of the catholyte comprises a compound of Formula (I) as described herein. |
| FILED | Monday, July 29, 2019 |
| APPL NO | 16/524666 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Heterocyclic Compounds C07D 211/94 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/188 (20130101) Original (OR) Class H01M 50/46 (20210101) H01M 50/411 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11271492 | Ravi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia) |
| ASSIGNEE(S) | VIRGINA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia) |
| INVENTOR(S) | Lakshmi Ravi (Blacksburg, Virginia); Joshua Stewart (Blacksburg, Virginia); Dong Dong (Blacksburg, Virginia); Rolando Burgos (Blacksburg, Virginia) |
| ABSTRACT | An inverter with a modular bus assembly is described. In various embodiments, the modular bus assembly includes a laminated motherboard and a plurality of capacitor daughtercards. The laminated motherboard can be configured to interface a plurality of phase-leg modules and a plurality of capacitor daughtercards through a plurality of terminals and connectors located on a bottom side or a top side of the laminated motherboard. The laminated motherboard includes a layer stack with a plurality of conductor layers. Each of the plurality of conductor layers is implemented with a net spacing from a neighboring plated through hole (PTH) based at least in part on differences in potential to be applied to each of the plurality of conductor layers as compared to a potential to be applied to the PTH. Embedded shield polygons can be implemented on the laminated motherboard to mitigate surface discharge at surface terminal (PTH/SMT) triple junctions. |
| FILED | Monday, July 27, 2020 |
| APPL NO | 16/939914 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/003 (20130101) Original (OR) Class Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/116 (20130101) H05K 1/0219 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11271747 | Murialdo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Maxwell R. Murialdo (Westminster, California); Brian Giera (San Mateo, California); Brian M. Howell (Livermore, California); Robert M. Panas (Dublin, California) |
| ABSTRACT | Systems and methods performed for generating authentication information for an image using optical computing are provided. When a user takes a photo of an object, an optical authentication system receives light reflected and/or emitted from the object. The system also receives a random key from an authentication server. The system converts the received light to plenoptic data and uploads it to the authentication server. In addition, the system generates an optical hash of the received light using the random key, converts the generated optical hash to a digital optical hash, and uploads the digital optical hash to the authentication server. When the authentication server receives the upload, it verifies whether the time of the upload is within a certain threshold time from the sending of the random key and whether the digital optical hash was generated from the same light as the plenoptic data. |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/571586 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/10 (20130101) G06F 21/64 (20130101) G06F 2221/0733 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Image Data Processing or Generation, in General G06T 7/0002 (20130101) G06T 2207/10052 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0643 (20130101) H04L 9/0819 (20130101) H04L 9/0877 (20130101) H04L 9/0894 (20130101) H04L 9/3236 (20130101) Original (OR) Class H04L 9/3247 (20130101) H04L 9/3297 (20130101) H04L 2209/38 (20130101) Pictorial Communication, e.g Television H04N 5/22541 (20180801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11272638 | Stoltz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Eaton Intelligent Power Limited (Dublin, Ireland) |
| ASSIGNEE(S) | Eaton Intelligent Power Limited (Dublin, Ireland) |
| INVENTOR(S) | Thomas Joseph Stoltz (Allen Park, Michigan); Glenn Clark Fortune (Farmington Hills, Michigan); Elizabeth Jane Mercer (West Bloomfield, Michigan); Viken Rafi Yeranosian (Sterling Heights, Michigan) |
| ABSTRACT | A motor drive converter includes a cold plate having a first side and a second side, the first side being opposite to the second side. The motor drive converter may further include at least one motor phase power electronics disposed on the first side of the cold plate, and a capacitor array disposed on the second side of the cold plate. The cold plate may include slots therethrough for a conductor to pass through the cold plate. The conductor may be configured to electrically coupling the capacitor array and the at least one motor phase power electronics. |
| FILED | Monday, April 20, 2020 |
| APPL NO | 16/853184 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 11/33 (20160101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20254 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11266768 | Grinstaff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Mark Grinstaff (Brookline, Massachusetts); Jonah Andrew Kaplan (Newton, Massachusetts); Julia Wang (Forest Hills, New York) |
| ABSTRACT | The disclosure provides a drug delivery device that can release a drug or other molecule of interest in response to application of a mechanical force, such as tension, and methods of use thereof. The present disclosure provides a tension-responsive drug delivery device by exploiting a difference in mechanical properties between a drug-loaded core material and a supertiydrophobic barrier coating consisting of interconnected micro- and nano-sized particles formulated via the electrospraying of a mixture of biocompatible polymers. |
| FILED | Wednesday, November 26, 2014 |
| APPL NO | 15/039136 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5031 (20130101) A61K 9/5146 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/34 (20130101) A61L 27/50 (20130101) A61L 27/54 (20130101) A61L 29/14 (20130101) A61L 29/16 (20130101) A61L 29/085 (20130101) A61L 31/10 (20130101) A61L 31/14 (20130101) Original (OR) Class A61L 31/16 (20130101) A61L 2400/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11266840 | Chae |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Junseok Chae (Scottsdale, Arizona) |
| ABSTRACT | Systems, devices, and methods involving cardiac pace making are provided. Implantable wireless pace making systems, devices, and methods using electromagnetic waveforms to interact with subcutaneous implanted sensors or stimulators, or both, are described. Systems, devices, and methods can include wireless, miniaturized, battery-free, radiofrequency (RF) microwave activated, sensors or stimulators or integrated sensor/stimulators that are implanted in multiple thoracic cavity locations, and interact with a remote pace making control-module or multiple modules. |
| FILED | Wednesday, June 26, 2019 |
| APPL NO | 16/453581 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/318 (20210101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3682 (20130101) A61N 1/3684 (20130101) Original (OR) Class A61N 1/3787 (20130101) A61N 1/37223 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267768 | Agrawal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| INVENTOR(S) | Rakesh Agrawal (West Lafayette, Indiana); Peter Oladipupo (West Lafayette, Indiana) |
| ABSTRACT | A process for producing olefins by cracking paraffins in the presence of methane. In the conventional steam cracking processes for olefin production, steam is used as a diluent in the feed mixture to the thermal cracker. In the processes provided herein, methane replaces steam as a diluent in the feed mixture to the thermal cracker. Replacing steam with methane as a diluent has a potential for cost savings in the construction and operation of a thermal cracking plant for olefin production. In addition, it leads to a much simpler cracking process compared to the conventional steam cracking technology as in the state of the art. |
| FILED | Friday, March 27, 2020 |
| APPL NO | 16/832092 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/062 (20130101) B01J 8/065 (20130101) B01J 8/085 (20130101) B01J 8/1827 (20130101) B01J 2208/065 (20130101) B01J 2208/00504 (20130101) Acyclic or Carbocyclic Compounds C07C 4/04 (20130101) Original (OR) Class C07C 4/06 (20130101) C07C 5/333 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268107 | Rodgers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington State University (Pullman, Washington); Baker Heart and Diabetes Institute (Melbourne, Australia) |
| ASSIGNEE(S) | Washington State University (Pullman, Washington); Baker Heart and Diabetes Institute (Melbourne, Australia) |
| INVENTOR(S) | Buel Dantese Rodgers (Pullman, Washington); Paul Gregorevic (Melbourne, Australia) |
| ABSTRACT | Described herein are vectors, such as adeno-associated virus (AAV) vectors, and recombinant AAV expressing Smad7. The disclosed AAV vectors and rAAV can be used for therapeutic applications in the treatment and amelioration of muscle wasting, cardiac and/or skeletal muscle wasting associated with cancer cachexia. |
| FILED | Friday, April 22, 2016 |
| APPL NO | 15/568244 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2750/14143 (20130101) C12N 2750/14171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268111 | Lynch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Michael David Lynch (Durham, North Carolina); Zhixia Ye (Raleigh, North Carolina) |
| ABSTRACT | The present disclosure provides compositions and methods for rapid production of chemicals in genetically engineered microorganisms in a large scale. Also provided herein is a high-throughput metabolic engineering platform enabling the rapid optimization of microbial production strains. The platform, which bridges a gap between current in vivo and in vitro bio-production approaches, relies on dynamic minimization of the active metabolic network. |
| FILED | Wednesday, February 21, 2018 |
| APPL NO | 16/487542 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/001 (20130101) C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/0016 (20130101) C12N 9/0051 (20130101) C12N 9/1025 (20130101) C12N 15/746 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/42 (20130101) Original (OR) Class C12P 13/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268127 | Lopez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Gabriel P. Lopez (Durham, North Carolina); Ashutosh Chilkoti (Durham, North Carolina); Ali Ghoorchian (Durham, North Carolina); Felipe Garcia Quiroz (Durham, North Carolina); Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Gabriel P. Lopez (Durham, North Carolina); Ashutosh Chilkoti (Durham, North Carolina); Ali Ghoorchian (Durham, North Carolina); Felipe Garcia Quiroz (Durham, North Carolina) |
| ABSTRACT | The presently disclosed subject matter relates to modular peptide-substrate protease assays, in particular low cost and reliable methodology for measurement of protease and other enzyme activity that may be detected by optical turbidimetry or visual observation. The presently disclosed subject matter also relates to methods of using the disclosed assays within methods of detecting and monitoring diseases, methods of drug discovery, as well as in detection devices and systems. |
| FILED | Wednesday, February 04, 2015 |
| APPL NO | 15/116750 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268196 | Chan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Candace Chan (Phoenix, Arizona); Jon Mark Weller (Phoenix, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Candace Chan (Phoenix, Arizona); Jon Mark Weller (Phoenix, Arizona) |
| ABSTRACT | Forming a lithium lanthanum zirconate thin film includes disposing zirconium oxide on a substrate to yield a zirconium oxide coating, contacting the zirconium oxide coating with a solution including a lithium salt and a lanthanum salt, heating the substrate to yield a dried salt coating on the zirconium oxide coating, melting the dried salt coating to yield a molten salt mixture, reacting the molten salt mixture with the zirconium oxide coating to yield lithium lanthanum zirconate, and cooling the lithium lanthanum zirconate to yield a lithium lanthanum zirconate coating on the substrate. In some cases, the zirconium oxide coating is contacted with an aqueous molten salt mixture including a lithium salt and a lanthanum salt, the molten salt mixture is reacted with the zirconium oxide coating to yield lithium lanthanum zirconate, and the lithium lanthanum zirconate is cooled to yield a lithium lanthanum zirconate coating on the substrate. |
| FILED | Thursday, October 31, 2019 |
| APPL NO | 16/669767 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/56 (20130101) C23C 16/405 (20130101) C23C 16/45555 (20130101) C23C 18/1216 (20130101) C23C 18/1295 (20130101) C23C 22/05 (20130101) C23C 22/70 (20130101) Original (OR) Class C23C 28/042 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0562 (20130101) H01M 2300/0077 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268200 | Oener et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Oregon (Eugene, Oregon) |
| ASSIGNEE(S) | University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Sebastian Oener (Eugene, Oregon); Shannon W. Boettcher (Eugene, Oregon); Marc Foster (Eugene, Oregon) |
| ABSTRACT | A bipolar membrane comprising a first member comprising at least one anion exchange material; a second member comprising at least one cation exchange material, wherein the first member and the second member together form an interface junction; and disposed within the interface junction a first layer comprising a first water dissociation catalyst and a second layer comprising a second water dissociation catalyst, wherein the first water dissociation catalyst is different than the second water dissociation catalyst. |
| FILED | Thursday, March 12, 2020 |
| APPL NO | 16/817502 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Separation B01D 61/445 (20130101) B01D 69/145 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/468 (20130101) B01J 23/755 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 9/23 (20210101) C25B 9/73 (20210101) C25B 13/04 (20130101) Original (OR) Class C25B 13/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268818 | Young et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRX SYSTEMS, INC. (Greenbelt, Maryland) |
| ASSIGNEE(S) | TRX SYSTEMS, INC. (Greenbelt, Maryland) |
| INVENTOR(S) | Travis Young (Rockville, Maryland); Kamiar Kordari (McLean, Virginia); Benjamin Funk (Hanover, Maryland); Carole Teolis (Glenn Dale, Maryland) |
| ABSTRACT | A location and mapping service is described that creates a global database of indoor navigation maps through crowd-sourcing and data fusion technologies. The navigation maps consist of a database of geo-referenced, uniquely described features in the multi-dimensional sensor space (e.g., including structural, RF, magnetic, image, acoustic, or other data) that are collected automatically as a tracked mobile device is moved through a building (e.g. a person with a mobile phone or a robot). The feature information can be used to create building models as one or more tracked devices traverse a building. |
| FILED | Wednesday, April 17, 2019 |
| APPL NO | 16/387483 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/32 (20130101) G01C 21/165 (20130101) G01C 21/206 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/0252 (20130101) G01S 19/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268892 | Sulchek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Todd Sulchek (Atlanta, Georgia); Alexander Alexeev (Atlanta, Georgia); Bushra Tasadduq (Atlanta, Georgia) |
| ABSTRACT | Embodiments of the present disclosure can include a method comprising: providing a plurality of cells to a microchannel, the microchannel coated in at least one cell adhesion entity and comprising a compressive surface and a first outlet, the compressive surface defining a compression gap, flowing the plurality of cells through the microchannel, wherein the flowing comprises: compressing the plurality of cells underneath the compressive surface; and exposing the plurality of cells to the at least one cell adhesion entity, wherein the exposing causes a first portion of the cells having a first adhesion property to temporarily bind to the cell adhesion entity; and collecting the first portion of cells at the first outlet; wherein the compression gap has a height of from 75% to 95% an average diameter of the plurality of cells. |
| FILED | Wednesday, November 08, 2017 |
| APPL NO | 16/348520 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 3/502776 (20130101) B01L 2200/0652 (20130101) B01L 2200/0668 (20130101) B01L 2300/16 (20130101) B01L 2300/0877 (20130101) B01L 2400/086 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) G01N 15/1056 (20130101) Original (OR) Class G01N 33/5005 (20130101) G01N 2015/1006 (20130101) G01N 2015/1081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268973 | Duncan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Texas Tech University System (Lubbock, Texas) |
| ASSIGNEE(S) | TEXAS TECH UNIVERSITY SYSTEM (Lubbock, Texas) |
| INVENTOR(S) | James Duncan (West Palm Beach, Florida); Brian Hirth (Lubbock, Texas); John Schroeder (Lubbock, Texas) |
| ABSTRACT | A system, method, and apparatus are disclosed for determining ABL wind field advection speed and direction comprising collecting at least two wind volumes from the ABL wind field, defining portions of the measurement domain within the at least two wind volumes for analysis, determining the advection of an isolated wind field between the at least two wind volumes, and iterating a process of correcting for intra-volume advection, objective analysis, and determining the inter-volume advective properties; wherein upon convergence of a measured advection profile, the advective properties of the ABL wind field have been appropriately derived. |
| FILED | Friday, March 15, 2019 |
| APPL NO | 16/355471 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 5/001 (20130101) Original (OR) Class G01P 5/26 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/95 (20130101) G01S 17/95 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11269047 | Riccardi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | InvenSense, Inc. (San Jose, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sebastian Riccardi (Brezins, France); Richard J. Przbyla (Piedmont, California); David A. Horsley (Berkeley, Canada); Mitchell H. Kline (Alameda, California) |
| ABSTRACT | A tracking method is disclosed. The method may include displaying visual content on a screen. A base station may be stationary with respect to the screen while the visual content is being displayed. In contrast, one or more objects may move with respect to the screen while the visual content is being displayed. The one or more objects may be tracked so that the movement thereof may be used to alter the visual content. Such tracking may involve the base station and the one or more objects sending and/or receiving one or more ultrasonic pulses. The tracked object also determines information using an inertial sensor assembly that receives a synchronization signal coordinated with the one or more ultrasonic pulses. Time-difference-of-arrival and/or time-of-flight of the one or more ultrasonic pulses may then be used to estimate a relative location and/or a relative orientation of the one or more objects with respect to the base station in three dimensional space, so that the estimate is fused with information determined by the inertial sensor assembly using the synchronization signal. |
| FILED | Thursday, December 06, 2018 |
| APPL NO | 16/212503 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/165 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/18 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/18 (20130101) G01S 5/26 (20130101) G01S 5/30 (20130101) Original (OR) Class G01S 5/186 (20130101) Electric Digital Data Processing G06F 3/017 (20130101) G06F 3/033 (20130101) G06F 3/0346 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11269149 | Fink et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Yoel Fink (Brookline, Massachusetts); Michael Rein (Boston, Massachusetts) |
| ABSTRACT | Provided is a fabric including a plurality of fibers disposed in a fabric configuration. At least one of the fibers comprises a device fiber having a device fiber body including a device fiber body material, having a longitudinal axis along a device fiber body length. A plurality of discrete devices are disposed as a linear sequence within the device fiber body along at least a portion of the device fiber body length. Each discrete device includes at least one electrical contact pad. The device fiber body includes device fiber body material regions disposed between adjacent discrete devices in the linear sequence, separating adjacent discrete devices. At least one electrical conductor is disposed within the device fiber body along at least a portion of the device fiber body length. The electrical conductor is disposed in electrical connection with an electrical contact pad of discrete devices within the device fiber body. |
| FILED | Wednesday, November 20, 2019 |
| APPL NO | 16/689453 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 1/005 (20130101) Non-portable Lighting Devices; Systems Thereof; Vehicle Lighting Devices Specially Adapted for Vehicle Exteriors F21S 4/10 (20160101) F21S 4/15 (20160101) Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 23/001 (20130101) Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to the Form or the Kind of the Light Sources or of the Colour of the Light Emitted F21Y 2103/30 (20160801) F21Y 2115/10 (20160801) Optical Elements, Systems, or Apparatus G02B 6/02033 (20130101) G02B 6/4416 (20130101) Original (OR) Class G02B 6/4479 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/023 (20130101) H01B 1/026 (20130101) H01B 3/30 (20130101) H01B 5/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11269179 | Tait et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Alexander N. Tait (Brooklyn, New York); Allie X. Wu (Florham Park, New Jersey); Thomas Ferreira de Lima (Princeton, New Jersey); Mitchell A. Nahmias (Menlo Park, California); Bhavin J. Shastri (Lawrenceville, New Jersey); Paul R. Prucnal (Princeton, New Jersey) |
| ABSTRACT | A system for photonic computing, preferably including: an input module, computation module, and/or control module, wherein the computation module preferably includes one or more filter banks and/or detectors. A photonic filter bank system, preferably including two waveguides and a plurality of optical filters arranged between the waveguides. A method for photonic computing, preferably including: controlling a computation module; controlling an input module; and/or receiving outputs from the computation module. |
| FILED | Wednesday, April 22, 2020 |
| APPL NO | 16/855222 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/0012 (20130101) Original (OR) Class Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/225 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11269294 | Javidi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | Bahram Javidi (Storrs, Connecticut); Adam Markman (Orange, Connecticut); Siddharth Rawat (Storrs, Connecticut); Arun Anand (Gujarat, India) |
| ABSTRACT | Portable common path shearing interferometry-based holographic microscopy systems. The system includes a light source, a sample holder, a microscope objective lens, a shear plate and an imaging device positioned in a common path shearing interferometry configuration. A housing is configured to receive and hold the shear plate and maintain a position of the shear plate relative to the microscope objective lens. |
| FILED | Monday, February 11, 2019 |
| APPL NO | 16/272581 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/453 (20130101) Holographic Processes or Apparatus G03H 1/02 (20130101) Original (OR) Class G03H 1/0005 (20130101) G03H 1/0443 (20130101) G03H 2001/005 (20130101) G03H 2001/0033 (20130101) G03H 2226/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11270031 | Savidis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Ioannis Savidis (Wallingford, Pennsylvania); Vaibhav Venugopal Rao (Philadelphia, Pennsylvania); Kyle Joseph Juretus (Quakertown, Pennsylvania) |
| ABSTRACT | The transition to a horizontal integrated circuit (IC) design flow has raised concerns regarding the security and protection of IC intellectual property (IP). Obfuscation of an IC has been explored as a potential methodology to protect IP in both the digital and analog domains in isolation. However, novel methods are required for analog mixed-signal circuits that both enhance the current disjoint implementations of analog and digital security measures and prevent an independent adversarial attack of each domain. A methodology generates functional and behavioral dependencies between the analog and digital domains that results in an increase in the adversarial key search space. The dependencies between the analog and digital keys result in a 3× increase in the number of iterations required to complete the SAT attack. |
| FILED | Wednesday, April 29, 2020 |
| APPL NO | 16/862111 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 21/75 (20130101) Original (OR) Class Pulse Technique H03K 5/1532 (20130101) H03K 21/02 (20130101) Coding; Decoding; Code Conversion in General H03M 1/365 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11270445 | Frank et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Lawrence R. Frank (San Diego, California); Vitaly L. Galinsky (San Diego, California) |
| ABSTRACT | A method for registering multiple data types of diverse modalities for a target volume includes acquiring at least at least two datasets associated with the target volume where the at least two datasets having different modalities. Using information field theory and entropy spectrum pathways theory, a local connectivity matrix is constructed for one or both of spatial connectivity and temporal connectivity for each of the datasets. The local connectivity matrices for the datasets are fused into a common coupling matrix and the datasets are merged to generate a registered image displaying the spatial and temporal features within the target volume. |
| FILED | Tuesday, March 06, 2018 |
| APPL NO | 16/491144 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/30 (20170101) Original (OR) Class G06T 2207/10044 (20130101) G06T 2207/10092 (20130101) G06T 2207/30016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11270790 | Torres |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Elizabeth B. Torres (Piscataway, New Jersey) |
| ABSTRACT | The present invention provides objective methods of diagnosis and behavioural treatments of neurological disorders such as autism spectral disorders and Parkinson's disease. |
| FILED | Thursday, December 06, 2018 |
| APPL NO | 16/212058 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/11 (20130101) A61B 5/0015 (20130101) A61B 5/40 (20130101) A61B 5/162 (20130101) A61B 5/168 (20130101) A61B 5/1104 (20130101) A61B 5/1114 (20130101) A61B 5/1124 (20130101) A61B 5/1125 (20130101) A61B 5/1128 (20130101) A61B 5/4076 (20130101) A61B 5/4082 (20130101) A61B 5/4088 (20130101) A61B 5/4094 (20130101) A61B 5/4848 (20130101) A61B 5/7264 (20130101) A61B 5/7275 (20130101) A61B 5/7278 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 20/70 (20180101) Original (OR) Class G16H 40/20 (20180101) G16H 50/20 (20180101) Information and Communication Technology [ICT] Specially Adapted for Specific Application Fields, Not Otherwise Provided for G16Z 99/00 (20190201) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/0428 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11271398 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| ASSIGNEE(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| INVENTOR(S) | Chengxi Liu (Knoxville, Tennessee); Kai Sun (Knoxville, Tennessee); Bin Wang (College Station, Texas); Xin Xu (Knoxville, Tennessee) |
| ABSTRACT | A multi-dimensional holomorphic embedding method for voltage control of an AC power system includes embedding multiple independent symbolic variables representing multiple control elements of the AC power system into AC power flow equations that describe the AC power system, analytically solving voltages for targeted buses of the AC power system in a form of multivariate power series or multivariable Padé approximants about the multiple independent symbolic variables such that coefficients of the multivariate power series or multivariable Padé approximants are obtained non-iteratively, and jointly adjusting the multiple control elements according to the multivariate power series or multivariable Padé approximants to control voltages of the targeted buses. |
| FILED | Friday, August 31, 2018 |
| APPL NO | 16/120022 |
| ART UNIT | 2148 — Semiconductors/Memory |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 19/2513 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/0012 (20200101) H02J 3/12 (20130101) Original (OR) Class H02J 2203/20 (20200101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 40/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11271533 | Narla et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Anirudh Narla (New Haven, Connecticut); Katrina Sliwa (New Haven, Connecticut); Michael Hatridge (New Haven, Connecticut); Shyam Shankar (New Haven, Connecticut); Luigi Frunzio (North Haven, Connecticut); Robert J. Schoelkopf, III (Madison, Connecticut); Michel Devoret (New Haven, Connecticut) |
| ABSTRACT | A wireless Josephson-junction-based amplifier is described that provides improved tunability and increased control over both a quality factor Q and participation ratio p of the amplifier. The device may be fabricated on a chip and mounted in a waveguide. No wire bonding between the amplifier and coaxial cables or a printed circuit board is needed. At least one antenna on the chip may be used to couple energy between the waveguide and wireless JBA. The amplifier is capable of gains greater than 25 dB. |
| FILED | Wednesday, March 07, 2018 |
| APPL NO | 15/914995 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Amplifiers H03F 19/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11271569 | Park et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Beomsoo Park (Gainesville, Florida); Nima Maghari (Gainesville, Florida) |
| ABSTRACT | The present disclosure describes systems, apparatuses, and methods for implementing a logic gate circuit structure for operating one or more Boolean functions. Instead of stacking transistors in series to accommodate an increased number of inputs, a parallel configuration is presented that significantly reduces the cascaded number of transistors and the total number of transistors for the same functionality. |
| FILED | Tuesday, December 29, 2020 |
| APPL NO | 17/136887 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Pulse Technique H03K 19/20 (20130101) Original (OR) Class H03K 19/0944 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11266801 | Fogarty et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Michael Fogarty (Provo, Utah); Joseph Orr (Park City, Utah); Kai Kuck (Park City, Utah) |
| ABSTRACT | A ventilation system having a mask, a blowing assembly, and a processor. The mask has a mask body and a pressure sensor operatively associated with the mask body and configured to measure pressure within the mask. The mask body defines an inlet opening and a plurality of leak openings. The blowing assembly is positioned in fluid communication with the inlet opening of the mask body and configured to direct air to the inlet opening of the mask body. The processor is positioned in operative communication with the blowing assembly and the pressure sensor of the mask. The processor is configured to selectively control the blowing assembly based upon at least the measured pressure within the mask. |
| FILED | Friday, October 07, 2016 |
| APPL NO | 15/767094 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/01 (20130101) A61M 16/0003 (20140204) A61M 16/06 (20130101) A61M 16/12 (20130101) A61M 16/024 (20170801) Original (OR) Class A61M 16/0051 (20130101) A61M 16/0069 (20140204) A61M 16/0084 (20140204) A61M 2016/0027 (20130101) A61M 2016/0033 (20130101) A61M 2202/0208 (20130101) A61M 2205/15 (20130101) A61M 2205/50 (20130101) A61M 2205/505 (20130101) A61M 2230/005 (20130101) A61M 2230/42 (20130101) A61M 2230/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267224 | Kang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Jin Ho Kang (Newport News, Virginia); Emille J. Siochi (Newport News, Virginia); Ronald K. Penner (Hampton, Virginia); Travis L. Turner (Yorktown, Virginia) |
| ABSTRACT | Provided are methods of preparing an electrically activated shape memory polymer composite capable of thermal shape reformation using electric power to heat the composite through its matrix glass transition temperature. The methods may include providing a polymer matrix component comprising a diglycidyl ether resin and at least one curing agent, adding into the polymer matrix component at least one nano-filler component, sonication and mixing the polymer matrix component and the nano-filler component to form a mixture, curing the mixture under curing conditions, and laminating the cured mixture with at least one elastic laminated layer. |
| FILED | Monday, October 23, 2017 |
| APPL NO | 15/790245 |
| ART UNIT | 1759 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 15/08 (20130101) B32B 15/092 (20130101) Original (OR) Class B32B 25/08 (20130101) B32B 25/20 (20130101) B32B 27/20 (20130101) B32B 27/38 (20130101) B32B 37/14 (20130101) B32B 2264/102 (20130101) B32B 2264/108 (20130101) B32B 2307/20 (20130101) B32B 2307/51 (20130101) B32B 2307/102 (20130101) B32B 2307/202 (20130101) B32B 2307/762 (20130101) B32B 2571/02 (20130101) B32B 2605/00 (20130101) B32B 2605/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11267589 | Bevilacqua et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida); United States Government Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida); United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Riccardo Bevilacqua (Gainesville, Florida); David C. Guglielmo (Gainesville, Florida); Sanny Omar (Gainesville, Florida); Laurence Fineberg (Kennedy Space Center, Florida); Justin Treptow (Kennedy Space Center, Florida); Scott Clark (Kennedy Space Center, Florida); Yusef Johnson (Kennedy Space Center, Florida); Bradley Poffenberger (Kennedy Space Center, Florida) |
| ABSTRACT | In an example embodiment, an attitude, orbit, and de-orbit control system (AODCS) for a satellite is provided. In an example embodiment, the AODCS system comprises one or more selectively retractable booms. The one or more selectively retractable booms are collectively configured to provide a selectively adjustable drag during de-orbiting of a satellite over a predefined de-orbiting time. |
| FILED | Tuesday, November 14, 2017 |
| APPL NO | 16/324396 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/32 (20130101) B64G 1/36 (20130101) B64G 1/66 (20130101) B64G 1/222 (20130101) Original (OR) Class B64G 1/242 (20130101) B64G 1/244 (20190501) B64G 1/285 (20130101) B64G 2001/245 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11269373 | Mautner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts) |
| INVENTOR(S) | Eric Karl Mautner (Hudson, Massachusetts); Brianna Klingensmith (Arlington, Massachusetts) |
| ABSTRACT | The present disclosure relates to systems and methods to maintain clock synchronization of multiple computers, or computer systems, through the exchange of communication messages that include clock and/or timing information. |
| FILED | Thursday, July 25, 2019 |
| APPL NO | 16/522175 |
| ART UNIT | 2187 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 1/12 (20130101) G06F 1/14 (20130101) Original (OR) Class G06F 13/122 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/0814 (20130101) H03L 7/0991 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 7/0025 (20130101) H04L 7/0037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 11271023 | Stanton |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Eric John Stanton (Boulder, Colorado) |
| ABSTRACT | A quantum waveguide infrared photodetector includes: a photon absorption layer that receives infrared photons propagating longitudinally along a longitudinal length of the photon absorption layer, converts the infrared photons into electrons, and communicates the electrons to a conductor layer; a first conductor layer that receives a first electrical potential; and a second conductor layer that receives a second electrical potential, wherein electrons produced by the photon absorption layer are communicated from the photon absorption layer: to the first conductor layer when the first electrical potential is more positive than the second electrical potential, and to the second conductor layer when the second electrical potential is more positive than the first electrical potential, an electrical current produced by the electrons is proportional to an amount of absorption of the infrared photons in the photon absorption layer. |
| FILED | Thursday, July 02, 2020 |
| APPL NO | 16/919515 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14625 (20130101) Original (OR) Class H01L 27/14669 (20130101) H01L 31/02327 (20130101) H01L 31/035218 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11271137 | Nikoobakht et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Babak Nikoobakht (Potomac, Maryland); Robin Paul Hansen (Rockville, Maryland) |
| ABSTRACT | A light article includes: a substrate; a truncated cuboidal fin disposed on the substrate and including: a laterally-grown nanocrystal including a longitudinal length and a lateral length that are different; a charge injection facet arranged along a longitudinal fin axis of the truncated cuboidal fin; and a truncation facet disposed opposing the charge injection facet and arranged parallel to the longitudinal fin axis; a side-injector disposed on the charge injection facet of the truncated cuboidal fin and that provides electrons to an active layer; and the active layer interposed between the side-injector and the substrate and that: receives electrons from the side-injector; receives holes from the substrate; and produces light in response to combining the electrons and the holes. |
| FILED | Friday, February 28, 2020 |
| APPL NO | 16/804203 |
| ART UNIT | 2898 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/06 (20130101) H01L 33/007 (20130101) H01L 33/24 (20130101) Original (OR) Class H01L 33/325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11272375 | Sahoo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Anirudha Sahoo (North Potomac, Maryland); Timothy Alan Hall (Gaithersburg, Maryland); Robert Charles Hagwood (Washington, District of Columbia) |
| ABSTRACT | A dynamic physical resource block control apparatus dynamically controls allocation of a physical resource block and includes: a dynamic spectrum arbitrage controller in communication with LTE wireless channels and a secondary user, the dynamic spectrum arbitrage controller: produces a status request to the LTE wireless channels, receives channel status response from the LTE wireless channels in response to the channel status request; receives a PRB allocation request from the secondary user; and produces a PRB map in response to the PRB allocation request; and LTE wireless channels in communication with a primary user and the secondary user and that: communicates a PRB map to the primary user; receives primary user data from the primary user; receives secondary user data from the secondary user. |
| FILED | Monday, April 06, 2020 |
| APPL NO | 16/841106 |
| ART UNIT | 2642 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0094 (20130101) Wireless Communication Networks H04W 16/10 (20130101) H04W 16/14 (20130101) Original (OR) Class H04W 24/02 (20130101) H04W 28/16 (20130101) H04W 72/0453 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11266131 | Guo |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Ximing Guo (Sewell, New Jersey) |
| ABSTRACT | Improved molluscan shellfish in diploid, tetraploid and triploid forms are provided. Also provided are methods for improving molluscan shellfish through progressive rotational crossbreeding and/or coalesced interploidy breeding. |
| FILED | Wednesday, March 13, 2019 |
| APPL NO | 16/352049 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 61/54 (20170101) A01K 67/0334 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268102 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Tong Geon Lee (Lithia, Florida); Samuel Forrest Hutton (Tampa, Florida) |
| ABSTRACT | Molecular markers associated with Solanaceae brachytic locus, methods of their use, and compositions having one or more marker loci are provided. Methods comprising detecting at least one marker locus, detecting a haplotype, and/or detecting a marker profile are provided. Methods and compositions are described for breeding tomato plants containing quantitative trait loci that are associated with brachytic phenotype and monitoring introgression of brachytic locus. Methods and compositions are also described for modifying a brachytic locus using CRISPR/Cas. |
| FILED | Wednesday, May 15, 2019 |
| APPL NO | 16/412901 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8213 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 11266618 | Rahbar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
| INVENTOR(S) | Samuel Rahbar (Beverly Hills, California); Timothy W. Synold (Monrovia, California); John Termini (Altadena, California); Daniel Tamae (Duarte, California); Gerald Wuenschell (Duarte, California) |
| ABSTRACT | Methods of quantifying N2-carboxyethyl-2′-deoxyguanosine (CEdG) levels in biological samples and comparing those levels to known normal levels can diagnose a number of disorders, including diabetes and cancer. Methods can also determine whether therapies for disorders are effective by measuring CEdG levels before and after treatment. Measurement of CEdG levels occurs using liquid chromatography electrospray ionization tandem mass spectrometry. |
| FILED | Friday, December 29, 2017 |
| APPL NO | 15/859188 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/195 (20130101) Original (OR) Class A61K 45/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/7233 (20130101) G01N 30/7266 (20130101) G01N 2030/045 (20130101) G01N 2030/8827 (20130101) G01N 2030/8868 (20130101) G01N 2800/042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11268102 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Tong Geon Lee (Lithia, Florida); Samuel Forrest Hutton (Tampa, Florida) |
| ABSTRACT | Molecular markers associated with Solanaceae brachytic locus, methods of their use, and compositions having one or more marker loci are provided. Methods comprising detecting at least one marker locus, detecting a haplotype, and/or detecting a marker profile are provided. Methods and compositions are described for breeding tomato plants containing quantitative trait loci that are associated with brachytic phenotype and monitoring introgression of brachytic locus. Methods and compositions are also described for modifying a brachytic locus using CRISPR/Cas. |
| FILED | Wednesday, May 15, 2019 |
| APPL NO | 16/412901 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8213 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Education (ED)
| US 11266342 | Huggins et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Jane E. Huggins (Fenton, Michigan); Seth Warschausky (Ann Arbor, Michigan); Ramses Eduardo Alcaide (Ann Arbor, Michigan) |
| ABSTRACT | Methods, systems, apparatus, and non-transitory computer readable media are disclosed utilizing brain-computer interfaces (BCIs). Various embodiments are disclosed to allow a user to directly select multiple-choice answers, to provide motorized wheelchair controls, and to allow a user to play a game via the BCI. When used in a cognitive assessment test, embodiments include the administration of unmodified standardized tests with results in the same or a similar format as those taken without a BCI. Various embodiments are disclosed to improve the accuracy of BCI test administration using a three-step process for each test question, which includes determining whether the user intends to select an answer, monitoring user brain activity to determine a selected answer, and verifying the selected answer. In addition, the selected answer may be verified by monitoring user brain activity in accordance with a hold-release process to determine whether a user intends to initiate a state change. |
| FILED | Friday, May 22, 2015 |
| APPL NO | 15/305030 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/316 (20210101) A61B 5/374 (20210101) A61B 5/378 (20210101) A61B 5/742 (20130101) A61B 5/4088 (20130101) Original (OR) Class A61B 5/7221 (20130101) A61B 5/7264 (20130101) A61B 5/7267 (20130101) A61B 5/7282 (20130101) A61B 5/7435 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/72 (20130101) A61F 4/00 (20130101) Electric Digital Data Processing G06F 3/015 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 7/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11269071 | Smith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Peter Roland Smith (Westfield, New Jersey); James Christopher Weatherall (Linwood, New Jersey); Jeffrey Brian Barber (Vineland, New Jersey); Barry Thomas Smith (Egg Harbor City, New Jersey) |
| ABSTRACT | The present disclosure is directed to a measurement system for measuring a reflection coefficient of a test sample, including: a transceiver antenna configured to be coupled to a source of electromagnetic radiation; and a RAM positioned between the transceiver antenna and a measurement region of the transceiver antenna, wherein the RAM comprises an aperture substantially orthogonal to and substantially aligned with a transceiving axis of the transceiver antenna. A method for obtaining error correction of a measurement system and a method of measuring a reflection coefficient in a test sample are also provided. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/244511 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/027 (20210501) G01S 7/40 (20130101) G01S 7/411 (20130101) G01S 13/88 (20130101) G01S 13/0209 (20130101) G01S 13/887 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 11267756 | Arce et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| INVENTOR(S) | Gabriel Andres Arce (Baton Rouge, Louisiana); Marwa Hassan (Baton Rouge, Louisiana); Hassan Noorvand (Baton Rouge, Louisiana); Tyson Rupnow (Baton Rouge, Louisiana); Michele Barbato (Baton Rouge, Louisiana) |
| ABSTRACT | Engineered Cementitious Composites (ECC) and cement products including Engineered Cementitious Composites are provided. The ECC can include cement, sugar cane bagasse ash, and fiber. The sugar cane bagasse ash can be processed to provide a partial cement or sand replacement in ECCs and cement products. |
| FILED | Thursday, April 02, 2020 |
| APPL NO | 16/838169 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 16/0633 (20130101) C04B 16/0641 (20130101) C04B 18/08 (20130101) C04B 18/24 (20130101) Original (OR) Class C04B 2103/302 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11266676 | Hughes-Fulford |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA as represented by THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (, None); The United States Government as represented by the Department of Veterans Affairs (, None) |
| INVENTOR(S) | Millie Hughes-Fulford (San Francisco, California) |
| ABSTRACT | Disclosed herein are methods for treating an immune system condition and/or altering T cell activation in a subject. Also disclosed herein are methods for diagnosing an immune system condition in a subject. In some examples, the methods can include measuring expression of at least one T cell activation-related miRNA in a sample obtained from a subject. The methods further include administering to the subject a therapeutically effective amount of an miRNA or mimic thereof, and/or an inhibitor of miRNA or mimic thereof and/or administering to the subject T cells contacted with an effective amount of miRNA or mimic thereof, and/or an inhibitor of miRNA or mimic thereof. |
| FILED | Friday, October 27, 2017 |
| APPL NO | 16/345512 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/141 (20130101) C12N 2330/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) C12Q 1/6883 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 11270919 | Arvelo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Amilcar R. Arvelo (Poughkeepsie, New York); Michael J. Ellsworth (Lagrangeville, New York); Eric J. McKeever (Poughkeepsie, New York); Thong N. Nguyen (Poughkeepsie, New York); Edward J. Seminaro (Milton, New York) |
| ABSTRACT | A method of forming a custom module lid. The method may include placing a multichip module (MCM) between a module base and a temporary lid, target components are exposed through viewing windows in the temporary lid, a top surface of the target components is measured and mapped to create a target profile, the target profile is used to form custom pockets in a custom lid, and the custom pockets correspond to the target components. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 16/205315 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/4817 (20130101) H01L 23/04 (20130101) H01L 23/06 (20130101) H01L 23/42 (20130101) H01L 23/043 (20130101) Original (OR) Class H01L 23/3675 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 3/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 11268102 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Tong Geon Lee (Lithia, Florida); Samuel Forrest Hutton (Tampa, Florida) |
| ABSTRACT | Molecular markers associated with Solanaceae brachytic locus, methods of their use, and compositions having one or more marker loci are provided. Methods comprising detecting at least one marker locus, detecting a haplotype, and/or detecting a marker profile are provided. Methods and compositions are described for breeding tomato plants containing quantitative trait loci that are associated with brachytic phenotype and monitoring introgression of brachytic locus. Methods and compositions are also described for modifying a brachytic locus using CRISPR/Cas. |
| FILED | Wednesday, May 15, 2019 |
| APPL NO | 16/412901 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8213 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11267826 | Burns et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VenatoRx Pharmaceuticals, Inc. (Malvern, Pennsylvania) |
| ASSIGNEE(S) | VENATORX PHARMACEUTICALS, INC. (Malvern, Pennsylvania) |
| INVENTOR(S) | Christopher J. Burns (Malvern, Pennsylvania); Denis Daigle (Street, Maryland); Guo-Hua Chu (Exton, Pennsylvania); Randy W. Jackson (Livingston, Montana); Jodie Hamrick (New Holland, Pennsylvania); Matthew Lucas (Malvern, Pennsylvania); Steven A. Boyd (Mars, Pennsylvania); Jiangchao Yao (Princeton, New Jersey); Eugen F. Mesaros (Wallingford, Pennsylvania) |
| ABSTRACT | Described herein are certain boron-containing compounds, compositions, preparations and their use as modulators of the transpeptidase function of bacterial penicillin-binding proteins and as antibacterial agents. In some embodiments, the compounds described herein inhibit penicillin-binding proteins. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections. |
| FILED | Friday, May 25, 2018 |
| APPL NO | 16/616382 |
| ART UNIT | 1699 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
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How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, March 08, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
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APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
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- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
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