FedInvent™ Patents
Patent Details for Tuesday, March 15, 2022
This page was updated on Wednesday, March 16, 2022 at 04:41 PM GMT
Department of Health and Human Services (HHS)
| US 11272843 | Sati et al. |
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| FUNDED BY |
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| APPLICANT(S) | Siemens Healthcare GmbH (Erlangen, Germany); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | Siemens Healthcare GmbH (Erlangen, Germany); The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Pascal Sati (Rockville, Maryland); Sunil Goraksha Patil (Ellicott City, Maryland); Daniel Reich (Washington, District of Columbia) |
| ABSTRACT | A computer-implemented method for automatically identifying subjects at risk of Multiple Sclerosis (MS) includes acquiring a plurality of images of a subject's brain using a Magnetic Resonance Imaging (MRI) scanner. A contrast enhancement process is applied to each image to generate a plurality of contrast-enhanced images. An automated lesion detection algorithm is applied to detect one or more lesions present in the contrast-enhanced images. An automated central vein detection algorithm is applied to detect one or more central veins present in the contrast-enhanced images. An automated paramagnetic rim detection algorithm is applied to detect one or more paramagnetic rims present in the contrast-enhanced images. The patient's risk for MS may then be determined based on the one or more of the lesions, central veins, and paramagnetic rims present in the contrast-enhanced images. |
| FILED | Wednesday, January 23, 2019 |
| APPL NO | 16/254710 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) Original (OR) Class A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) G01R 33/56509 (20130101) Image Data Processing or Generation, in General G06T 5/00 (20130101) G06T 7/0012 (20130101) G06T 2207/10088 (20130101) G06T 2207/20024 (20130101) G06T 2207/20081 (20130101) G06T 2207/20172 (20130101) G06T 2207/30016 (20130101) G06T 2207/30096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11272956 | McDonnall et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ripple, LLC (Salt Lake City, Utah) |
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| INVENTOR(S) | Daniel Allen McDonnall (Salt Lake City, Utah); Nathaniel Anthony Srok (Salt Lake City, Utah); Christopher Farand Smith (North Salt Lake, Utah) |
| ABSTRACT | Disclosed herein are systems and methods for insertion tools for implanting electrode leads. In one embodiment, an insertion tool comprises a shaft having an outer cannula and an inner cannula. An actuator may be configured to transition the insertion tool between at least three configurations. In a first configuration, the inner cannula and the outer cannula are configured to receive the lead in the shaft. In a second configuration, the inner cannula and the outer cannula are configured to secure the lead in the shaft. In a third configuration, the inner cannula and the outer cannula are configured to cause the lead to separate from the insertion tool and implant in adjacent tissue. |
| FILED | Sunday, March 17, 2019 |
| APPL NO | 16/355804 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/3421 (20130101) A61B 17/3468 (20130101) Original (OR) Class A61B 2017/00367 (20130101) A61B 2017/00438 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/72 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11273130 | Kim et al. |
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| FUNDED BY |
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| APPLICANT(S) | Peptron, Inc. (Daejeon, South Korea); The United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
| ASSIGNEE(S) | The United States, as represented by the Secretary Department of Health and Human Services (Rockville, Maryland); Peptron, Inc. (Daejeon, South Korea) |
| INVENTOR(S) | Dong Seok Kim (Columbia, Maryland); Hee Kyung Kim (Daejeon, South Korea); Nigel H. Greig (Phoenix, Maryland) |
| ABSTRACT | The present disclosure provides a method for delivering a neuroprotective polypeptide to at least a portion of a central nervous system (CNS) of a subject. The method includes administering to the systemic blood circulation of the subject a therapeutically effective amount of a neuroprotective polypeptide by a controlled-release formulation or a device providing a sustained release of the neuroprotective polypeptide including at least one neuroprotective polypeptide selected from the group consisting of GLP-1, exendin-4, or a therapeutically effective GLP-1 or exendin-4 analogue; the neuroprotective polypeptide binds to and activates a receptor that binds at least one of GLP-1, exendin-4, or a combination thereof; and the controlled-release neuroprotective formulation or the sustained release of the neuroprotective polypeptide enhances the delivery of the neuroprotective polypeptide across a blood-brain barrier (BBB) of the subject to at least a portion of the CNS relative to a rapid release formulation of the neuroprotective polypeptide. Also disclosed is a method of treating a subject with a CNS-related disease or reducing at least one symptom of a CNS-related disease in a subject in need thereof. |
| FILED | Friday, October 20, 2017 |
| APPL NO | 16/342685 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/4866 (20130101) A61K 9/5031 (20130101) Original (OR) Class A61K 38/26 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/14228 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) A61P 25/28 (20180101) A61P 25/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11273138 | Wolfe et al. |
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| FUNDED BY |
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| APPLICANT(S) | BioVentures, LLC (Little Rock, Arkansas) |
| ASSIGNEE(S) | BioVentures, LLC (Little Rock, Arkansas) |
| INVENTOR(S) | Robert R. Wolfe (Little Rock, Arkansas); Arny Ferrando (Little Rock, Arkansas) |
| ABSTRACT | The present invention encompasses an amino acid composition for stimulating muscle protein synthesis. Further, the present disclosure relates generally to the use of an anabolic amino acid composition for the stimulation of muscle protein synthesis. In particular, disclosed are compositions and methods of using the same for the prevention and/or treatment of a loss of any one of muscle mass, muscle strength, muscle function, and physical function, or any combination thereof, in a mammal, especially an adult mammal. Also provided are kits comprising a composition for the stimulation of muscle protein synthesis and, in certain embodiments, instructions for administration. |
| FILED | Friday, November 02, 2018 |
| APPL NO | 16/761175 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/175 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 31/198 (20130101) Original (OR) Class A61K 31/405 (20130101) A61K 31/4172 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11273167 | Lishko et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Polina V. Lishko (Berkeley, California); Yuriy Kirichok (San Francisco, California); Melissa R. Miller (Berkeley, California) |
| ABSTRACT | The present disclosure provides compositions and methods of modulating abhydrolase domain-containing protein-2 (ABHD2). The present disclosure provides methods of identifying agents that modulate ABHD2 activity. |
| FILED | Monday, August 01, 2016 |
| APPL NO | 15/747104 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) A61K 31/66 (20130101) Original (OR) Class A61K 31/713 (20130101) A61K 38/465 (20130101) A61K 39/395 (20130101) Peptides C07K 16/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/061 (20130101) C12N 5/0619 (20130101) C12N 5/0688 (20130101) C12N 15/1137 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/44 (20130101) Enzymes C12Y 301/01 (20130101) C12Y 301/01023 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) G01N 33/6872 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11273176 | Balestrieri |
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| FUNDED BY |
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| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Barbara Balestrieri (Marblehead, Massachusetts) |
| ABSTRACT | Methods to reduce the inflammatory response critical in the pathogenesis of asthma and asthma exacerbations via the introduction of autologous Pla2g5-deficient suppressive macrophages into the airways of patients with asthma. |
| FILED | Thursday, March 02, 2017 |
| APPL NO | 16/080905 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) Original (OR) Class A61K 38/19 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/06 (20180101) A61P 29/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0645 (20130101) C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2501/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11273183 | Harrell |
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| FUNDED BY |
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| APPLICANT(S) | MAM Holdings of West Florida, L.L.C. (Tarpon Springs, Florida) |
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| INVENTOR(S) | Carl Randall Harrell (Tarpon Springs, Florida) |
| ABSTRACT | A human amniotic fluid formulation has been developed for administration into a joint or associated soft tissue such as a tendon or ligament for treatment of pain, degeneration or injury. The formulation is a sterile de-cellularized human amniotic fluid (D-HAF), devoid of amniotic stem cells and elements of micronized membrane or chorion particles, which has not been heat treated or treated with ethidium bromide. The formulation is optionally diluted, or concentrated, depending on he severity of the disorder or injury. Examples demonstrate efficacy in treatment of pain, disease, disorder, degeneration or injury of a joint or associated soft. |
| FILED | Monday, March 05, 2018 |
| APPL NO | 15/912096 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/14 (20130101) A61K 9/0019 (20130101) A61K 9/19 (20130101) A61K 35/50 (20130101) Original (OR) Class A61K 38/18 (20130101) A61K 45/06 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 27/3604 (20130101) A61L 27/3654 (20130101) A61L 27/3683 (20130101) A61L 31/005 (20130101) A61L 31/16 (20130101) A61L 2300/412 (20130101) A61L 2300/414 (20130101) A61L 2400/06 (20130101) A61L 2430/02 (20130101) A61L 2430/06 (20130101) A61L 2430/24 (20130101) A61L 2430/40 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/00 (20180101) A61P 19/02 (20180101) A61P 19/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11273209 | Khalili et al. |
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| FUNDED BY |
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| APPLICANT(S) | Temple University of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Temple University of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Kamel Khalili (Bala Cynwyd, Pennsylvania); Wenhui Hu (Cherry Hill, New Jersey); Yonggang Zhang (Maple Shade, New Jersey) |
| ABSTRACT | Compositions for specifically cleaving target sequences in retroviruses include nucleic acids encoding a Clustered Regularly Interspace Short Palindromic Repeat (CRISPR) associated endonuclease and a guide RNA sequence complementary to one or more target nucleic acid sequences in a retrovirus genome. |
| FILED | Friday, May 15, 2020 |
| APPL NO | 16/875271 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) Original (OR) Class A61K 48/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/907 (20130101) C12N 15/1132 (20130101) C12N 2310/10 (20130101) C12N 2310/20 (20170501) C12N 2320/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11273214 | Collins et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH and HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Peter L. Collins (Silver Spring, Maryland); Ursula J. Buchholz (Silver Spring, Maryland); Bo Liang (Bethesda, Maryland); Shirin Munir (Bethesda, Maryland) |
| ABSTRACT | Recombinant chimeric bovine/human parainfluenza virus 3 (rB/HPIV3) vectors expressing Respiratory Syncytial Virus (RSV) G protein or a recombinant RSV G protein, as well as methods of their use and manufacture, are provided. The rB/HPIV3 vector comprises a genome comprising a heterologous gene encoding the RSV G protein or the recombinant RSV G protein. Nucleic acid molecules comprising the sequence of the genome or antigenome of the disclosed rB/HPIV3 vectors are also provided. The disclosed rB/HPIV3 vectors can be used, for example, to induce an immune response to RSV and HPIV3 in a subject. |
| FILED | Tuesday, May 29, 2018 |
| APPL NO | 16/616873 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/543 (20130101) A61K 2039/575 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2760/18534 (20130101) C12N 2760/18571 (20130101) C12N 2760/18643 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11273227 | Boesze-Battaglia |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Kathleen Boesze-Battaglia (Haddon Heights, New Jersey) |
| ABSTRACT | Engineered MREG proteins are described. Further described are viral vectors expressing native or engineered MREG proteins. Further described are compositions containing these vectors or proteins formulated for delivery to the eye. Also provided are methods for delivering these native and engineered MREG proteins to ocular cells for treatment of Stargardt's disease, macular degeneration and other ocular disorders. |
| FILED | Friday, October 07, 2016 |
| APPL NO | 15/766973 |
| ART UNIT | 1699 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 38/00 (20130101) A61K 38/1709 (20130101) A61K 48/005 (20130101) A61K 48/0058 (20130101) Original (OR) Class A61K 48/0075 (20130101) A61K 2039/515 (20130101) Peptides C07K 14/47 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14143 (20130101) C12N 2830/15 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11273236 | Alsberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); Worcester Polytechnic Institute (Worcester, Massachusetts) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); WORCESTER POLYTECHNIC INSTITUTE (Worcester, Massachusetts) |
| INVENTOR(S) | Eben Alsberg (Cleveland, Ohio); Anna D. Dikina (Mentor, Ohio); Marsha W. Rolle (Worcester, Massachusetts); Hannah A. Strobel (Marlborough, Massachusetts) |
| ABSTRACT | A modular engineered tissue construct includes a plurality of fused self-assembled, scaffold-free, high-density cell aggregates. At least one cell aggregate includes a plurality of cells and a plurality of biocompatible and biodegradable nanoparticles and/or microparticles that are incorporated within the cell aggregates. The nanoparticles and/or microparticles acting as a bulking agent within the cell aggregate to increase the cell aggregate size and/or thickness and improve the mechanical properties of the cell aggregate as well as to deliver bioactive agents. |
| FILED | Thursday, September 07, 2017 |
| APPL NO | 15/698429 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 35/32 (20130101) A61K 35/42 (20130101) A61K 35/44 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 27/58 (20130101) A61L 27/3804 (20130101) A61L 27/3817 (20130101) Original (OR) Class A61L 27/3839 (20130101) A61L 27/3886 (20130101) A61L 2300/62 (20130101) A61L 2300/414 (20130101) A61L 2400/12 (20130101) A61L 2430/02 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 25/14 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0655 (20130101) C12N 5/0697 (20130101) C12N 2533/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11273329 | Konofagou et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Elisa E. Konofagou (New York, New York); Fabrice Marquet (New York, New York); Yao-Sheng Tung (New York, New York) |
| ABSTRACT | Systems and methods for cavitation-guided opening of a targeted region of tissue within a primate skull are provided. In one example, a method includes delivering one or more microbubbles to proximate the targeted region, applying an ultrasound beam, using a transducer, through the skull of the primate to the targeted region to open the tissue, transcranially acquiring acoustic emissions produced from an interaction between the one or more microbubbles and the tissue, and determining a cavitation spectrum from the acquired acoustic emissions. |
| FILED | Wednesday, September 18, 2019 |
| APPL NO | 16/575044 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/481 (20130101) A61B 8/0808 (20130101) A61B 17/2258 (20130101) A61B 90/10 (20160201) A61B 2017/00106 (20130101) A61B 2017/22008 (20130101) A61B 2017/22089 (20130101) A61B 2090/378 (20160201) A61B 2503/40 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class A61N 2007/0039 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11273447 | Han et al. |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Bumsoo Han (West Lafayette, Indiana); George Tsu-Chih Chiu (West Lafayette, Indiana); Thomas Heinrich Siegmund (West Lafayette, Indiana); Michael Linnes (West Lafayette, Indiana); Yumeng Wu (West Lafayette, Indiana); Matthew Tyler Short (Sudbury, Massachusetts) |
| ABSTRACT | Multi-well collapsible basket arrays and methods for their use with high throughput culture and histology analysis of spheroids and organoids. Such a collapsible basket array includes a collapsible cellular array structure having multiple cells and connectors that interconnect adjacent pairs of the cells to cause the collapsible cellular array structure to collapse from an expanded configuration to a collapsed configuration in which the connectors are partially wrapped around perimeters or circumferences of the cells, whereby the collapsible cellular array structure is expandable to acquire an expanded configuration capable of individually aligning the cells thereof with wells of a well plate. The collapsible basket array further includes inserts individually mountable to the cells of the collapsible cellular array structure, with each insert including a permeable basket with pores sized to retain spheroids or organoids within the basket. |
| FILED | Monday, January 13, 2020 |
| APPL NO | 16/741222 |
| ART UNIT | 1799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5055 (20130101) Original (OR) Class B01L 2200/021 (20130101) B01L 2300/123 (20130101) B01L 2300/0893 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/26 (20130101) C12M 23/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274077 | Maloney et al. |
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| FUNDED BY |
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| APPLICANT(S) | Eastern Virginia Medical School (Norfolk, Virginia); The Regents of the Univ. of California Santa Cruz (Oakland, California); The U.S. Dept of Health and Human Services (Bethesda, Maryland); Thomas Jefferson University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Eastern Virginia Medical School (Norfolk, Virginia); The Regents of the University of California Santa (Oakland, California); The United States of America Department of Health (Bethesda, Maryland); Thomas Jefferson University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | David J. Maloney (Point Of Rocks, Maryland); Diane K. Luci (Germantown, Maryland); Ajit Jadhav (Chantilly, Virginia); Theodore Holman (Santa Cruz, California); Jerry L. Nadler (Norfolk, Virginia); Michael Holinstat (Wallingford, Pennsylvania); David Taylor-Fishwick (Norfolk, Virginia); Anton Simeonov (Bethesda, Maryland); Adam Yasgar (Washington, District of Columbia); Steven McKenzie (Springfield, Pennsylvania) |
| ABSTRACT | Human lipoxygenases (LOXs) are a family of iron-containing enzymes involved in catalyzing the oxidation of polyunsaturated fatty acids to provide the corresponding bioactive hydroxyeicosatetraenoic acid (HETE) metabolites. These eicosanoid signaling molecules are involved in a number of physiologic responses such as platelet aggregation, inflammation, and cell proliferation. Platelet-type 12-(S)-LOX (12-LOX) is of particular interest because of its demonstrated role in skin diseases, diabetes, platelet hemostasis, thrombosis, and cancer. Disclosed herein is the identification and medicinal chemistry optimization of a 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide-based scaffold. The compounds display nM potency against 12-LOX and excellent selectivity over related lipoxygenases and cyclooxygenases. In addition to possessing favorable ADME properties, the compounds also inhibit PAR-4 induced aggregation and calcium mobilization in human platelets, and reduce 12-HETE in mouse/human beta cells. The compounds can also be used in methods for treating or preventing a 12-lipoxygenase mediated disease or disorder. |
| FILED | Tuesday, June 23, 2020 |
| APPL NO | 16/909712 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/02 (20180101) Acyclic or Carbocyclic Compounds C07C 311/44 (20130101) Original (OR) Class Heterocyclic Compounds C07D 211/28 (20130101) C07D 213/76 (20130101) C07D 217/02 (20130101) C07D 217/22 (20130101) C07D 235/30 (20130101) C07D 239/69 (20130101) C07D 261/16 (20130101) C07D 263/58 (20130101) C07D 277/52 (20130101) C07D 277/82 (20130101) C07D 295/135 (20130101) C07D 333/36 (20130101) C07D 417/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274115 | Bazin-Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | GLAXOSMITHKLINE BIOLOGICALS SA (Rixensart, Belgium) |
| ASSIGNEE(S) | GLAXOSMITHKLINE BIOLOGICAL SA (Rixensart, Belgium) |
| INVENTOR(S) | Helene G. Bazin-Lee (Hamilton, Montana); Jay T. Evans (Hamilton, Montana); David Burkhart (Hamilton, Montana); Michael Cochran (Hamilton, Montana); David A. Johnson (Hamilton, Montana) |
| ABSTRACT | This invention relates inter alia to novel imidazoquinoline derivatives and their use in therapy, particularly as vaccine adjuvants. |
| FILED | Tuesday, September 05, 2017 |
| APPL NO | 16/330599 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/6561 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274116 | Gin et al. |
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| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York City, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | David Y. Gin (New York, New York); Eric K. Chea (Flushing, New York); Alberto Fernandez-Tejada (New York, New York); Derek S. Tan (New York, New York); Jason S. Lewis (New York, New York); Jeffrey R. Gardner (New York, New York); NagaVarakishore Pillarsetty (Jackson Heights, New York) |
| ABSTRACT | Truncated triterpene saponin analogues containing a trisaccharide or tetrasaccharide ester are disclosed. Also disclosed are pharmaceutical compositions comprising truncated saponin analogues and synthetic methods of producing the truncated saponin analogues. Another aspect of the present application relates to a method for immunizing a subject, comprising administering to the subject the pharmaceutical composition comprising a minimal saponin analogue and an antigen. |
| FILED | Monday, April 20, 2020 |
| APPL NO | 16/853393 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 31/7024 (20130101) A61K 31/7024 (20130101) A61K 39/39 (20130101) A61K 45/06 (20130101) A61K 2039/55577 (20130101) A61K 2300/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/18 (20130101) C07H 15/24 (20130101) C07H 15/256 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274126 | Reshetnyak et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Rhode Island Board of Trustees (Kingston, Rhode Island) |
| ASSIGNEE(S) | University of Rhode Island Board of Trustees (Kingston, Rhode Island) |
| INVENTOR(S) | Yana K. Reshetnyak (South Kingstown, Rhode Island); Oleg A. Andreev (South Kingstown, Rhode Island); Keykavous Parang (Irvine, California) |
| ABSTRACT | The present subject matter provides pH triggered peptides, as well as compositions methods, devices, and systems comprising the same. The pH triggered peptides include cyclic and short linear peptides, and may have higher affinity to a membrane lipid bilayer at low pH than at neutral or high pH. |
| FILED | Tuesday, March 21, 2017 |
| APPL NO | 16/087628 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/44 (20130101) A61K 8/64 (20130101) A61K 38/00 (20130101) A61K 45/06 (20130101) A61K 49/0043 (20130101) A61K 49/0056 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 17/005 (20130101) A61Q 19/08 (20130101) Peptides C07K 7/08 (20130101) C07K 7/64 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274128 | Klapoetke et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of the University of Alberta (Edmonton, Canada) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of the University of Alberta (Edmonton, Canada) |
| INVENTOR(S) | Nathan Klapoetke (Ashburn, Virginia); Brian Yichiun Chow (Cherry Hill, New Jersey); Edward Boyden (Chestnut Hill, Massachusetts); Gane Ka-Shu Wong (Edmonton, Canada); Yongku Peter Cho (Vernon, Connecticut) |
| ABSTRACT | The invention, in some aspects relates to compositions and methods for altering cell activity and function and the introduction and use of light-activated ion channels. |
| FILED | Thursday, May 28, 2020 |
| APPL NO | 16/885457 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 41/0023 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 2005/0661 (20130101) A61N 2005/0662 (20130101) Peptides C07K 14/405 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5041 (20130101) G01N 33/5058 (20130101) G01N 33/48728 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274131 | Pease et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota) |
| ASSIGNEE(S) | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota) |
| INVENTOR(S) | Larry R. Pease (Rochester, Minnesota); Moses Rodriguez (Rochester, Minnesota) |
| ABSTRACT | Materials and methods for using multivalent molecules (e.g., antibodies) to modulate cellular function. A molecule can be targeted to a particular type of cell, either through direct binding to an epitope on the surface of the cell, or through a linker that recognizes both the multivalent molecule and a marker on the cell surface. |
| FILED | Thursday, December 27, 2018 |
| APPL NO | 16/233773 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/4726 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274144 | Goodman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Research Institute at Nationwide Children's Hospital (Columbus, Ohio) |
| ASSIGNEE(S) | Research Institute at Nationwide Children's Hospital (Columbus, Ohio) |
| INVENTOR(S) | Steven D. Goodman (Hilliard, Ohio); Lauren O. Bakaletz (Hilliard, Ohio) |
| ABSTRACT | This disclosure provides isolated or recombinant polypeptides that are useful to vaccinate individuals suffering from chronic/recurrent biofilm disease or as a therapeutic for those with an existing infection. The individual's immune system will then naturally generate antibodies which prevent or clear these bacteria from the host by interfering with the construction and or maintenance of a functional protective biofilm. Alternatively, antibodies to the polypeptides can be administered to treat or prevent infection. Bacteria that cannot form functional biofilms are more readily cleared by the remainder of the host's immune system and/or traditional antibiotics. |
| FILED | Thursday, August 16, 2018 |
| APPL NO | 15/999215 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/46 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 39/40 (20130101) A61K 39/0208 (20130101) A61K 39/39541 (20130101) A61K 39/39541 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/12 (20130101) C07K 16/40 (20130101) C07K 16/1232 (20130101) C07K 16/1242 (20130101) Original (OR) Class C07K 2317/34 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) G01N 33/6893 (20130101) G01N 33/56911 (20130101) G01N 2500/04 (20130101) G01N 2800/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274146 | Song et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Wenchao Song (Bryn Mawr, Pennsylvania); Sayaka Sato (Philadelphia, Pennsylvania); Takashi Miwa (Bala Cynwyd, Pennsylvania); Damodar Gullipalli (Philadelphia, Pennsylvania) |
| ABSTRACT | This invention relates to inhibition of the complement signaling using an anti-C5a antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5a antibody. |
| FILED | Friday, March 23, 2018 |
| APPL NO | 16/495979 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/18 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/54 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 2015/8518 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274298 | June et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Carl H. June (Merion Station, Pennsylvania); Yangbing Zhao (Lumberton, New Jersey) |
| ABSTRACT | The present invention relates to compositions and methods for generating RNA Chimeric Antigen Receptor (CAR) transfected T cells. The RNA-engineered T cells can be used in adoptive therapy to treat cancer. |
| FILED | Tuesday, September 03, 2019 |
| APPL NO | 16/559122 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 45/06 (20130101) A61K 48/00 (20130101) Peptides C07K 14/82 (20130101) C07K 2319/03 (20130101) C07K 2319/72 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Original (OR) Class C12N 2799/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274301 | Pandolfi et al. |
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| FUNDED BY |
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| APPLICANT(S) | BETH ISRAEL DEACONESS MEDICAL CENTER (Boston, Massachusetts) |
| ASSIGNEE(S) | BETH ISRAEL DEACONESS MEDICAL CENTER (Boston, Massachusetts) |
| INVENTOR(S) | Pier Paolo Pandolfi (Boston, Massachusetts); Laura Poliseno (New York, New York); Yvonne Tay (Brookline, Massachusetts); Leonardo Salmena (Brookline, Massachusetts) |
| ABSTRACT | The invention relates to the treatment and prevention of cancer by administering agents that inhibit the activity of microRNAs that modulate tumor suppressor genes, which can include PTEN, p53, and INPP4B, among others. Inhibitors can include oligonucleotides that are at least partially complementary to these miRNAs. In some embodiments, these inhibitors are chemically modified oligonucleotides, including locked nucleic acids (LNAs). |
| FILED | Friday, October 06, 2017 |
| APPL NO | 15/727156 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/113 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/3231 (20130101) C12N 2320/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274303 | Pajukanta et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); UNITED STATES GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia); UNIVERSITY OF EASTERN FINLAND (Kuopio, Finland) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); UNITED STATES GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia); UNIVERSITY OF EASTERN FINLAND (Kuopio, Finland) |
| INVENTOR(S) | Paivi E. Pajukanta (Los Angeles, California); Joseph R. Pisegna (Los Angeles, California); Jihane N. Benhammou (Los Angeles, California); Arthur Ko (Los Angeles, California); Jussi Pihlajamäki (Kuopio, Finland) |
| ABSTRACT | An oligonucleotide that inhibits expression of an OLMALINC nucleic acid molecule, such as a small inhibitory RNA (siRNA) molecule, can be used for inhibiting the expression of OLMALINC in a subject. Methods of assaying for OLMALINC in a tissue sample can be used for detecting a disorder associated with obesity and/or type 2 diabetes in a tissue sample obtained from a subject. A method of ameliorating symptoms associated with obesity and/or type 2 diabetes comprises administering to a subject in need thereof an effective amount of an oligonucleotide of the invention or an antibody or equivalent thereof that specifically binds to and inactivates an OLMALINC nucleic acid molecule. Representative examples of a disorder associated with obesity and/or type 2 diabetes include, but are not limited to, a disorder of appetite, glycemia, body weight, liver steatosis, NASH, NAFLD, or a lipid disorder. |
| FILED | Friday, October 05, 2018 |
| APPL NO | 16/753962 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/20 (20170501) C12N 2310/113 (20130101) C12N 2320/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274318 | Doudna et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); University of Vienna (Vienna, Austria); Emmanuelle Charpentier (Berlin, Germany) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); University of Vienna (Vienna, Austria); Emmanuelle Charpentier (Berlin, Germany) |
| INVENTOR(S) | Jennifer A. Doudna (Berkeley, California); Martin Jinek (Berkeley, California); Krzysztof Chylinski (Vienna, Austria); Emmanuelle Charpentier (Berlin, Germany) |
| ABSTRACT | The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms. |
| FILED | Friday, May 21, 2021 |
| APPL NO | 17/326818 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 6/4684 (20180501) Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/027 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/63 (20130101) C12N 15/70 (20130101) C12N 15/90 (20130101) C12N 15/102 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/746 (20130101) C12N 15/902 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/13 (20130101) C12N 2310/14 (20130101) C12N 2310/20 (20170501) C12N 2310/31 (20130101) C12N 2310/32 (20130101) C12N 2310/33 (20130101) C12N 2310/531 (20130101) C12N 2310/3519 (20130101) C12N 2800/80 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Enzymes C12Y 301/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274345 | Khatri et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Purvesh Khatri (Menlo Park, California); Timothy E. Sweeney (San Francisco, California) |
| ABSTRACT | Methods for diagnosis of bacterial and viral infections are disclosed. In particular, the invention relates to the use of biomarkers that can determine whether a patient with acute inflammation has a bacterial or viral infection. |
| FILED | Monday, June 05, 2017 |
| APPL NO | 16/096261 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 1/701 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274349 | Di Vizio et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Dolores Di Vizio (Los Angeles, California); Valentina R. Minciacchi (Los Angeles, California); Andrew Conley (Los Angeles, California) |
| ABSTRACT | Provided herein are methods for diagnosing cancer in a subject by determining the gene expression level of one or more genes in extracellular vesicles isolated from samples obtained from a subject. |
| FILED | Wednesday, November 08, 2017 |
| APPL NO | 16/335605 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6851 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275079 | Boyden et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Edward Boyden (Chestnut Hill, Massachusetts); Kiryl Piatkevich (Quincy, Massachusetts); Eunjung Jung (Cambridge, Massachusetts) |
| ABSTRACT | Voltage reporter molecules and compositions, and methods for detecting voltage and voltage change in cells are provided. Also provided are methods for delivery, expression, and use of the voltage reporter molecules in cells, tissues, and subjects. |
| FILED | Tuesday, July 03, 2018 |
| APPL NO | 16/026551 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/705 (20130101) C07K 14/43504 (20130101) C07K 2319/60 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/1717 (20130101) G01N 33/502 (20130101) Original (OR) Class G01N 2021/1721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275080 | Tumeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Paul C. Tumeh (Santa Monica, California); Antoni Ribas (Los Angeles, California) |
| ABSTRACT | A method of analyzing a biological sample from a subject that has a tumor or cancer, comprising: determining, for target cells having a phenotype of interest spatial resolution of the target cells, density of the spatially resolved target cells in the sample; and proximity between spatially resolved target cells of interest in the sample; and determining an overall score based at least in part on the preceding parameters. A method for identifying a patient as a responder to single agent anti-PD-1 or anti-PD-L1 therapy is provided. Similar methods are provided for detecting adaptive immune resistance, the presence of cancer in a patient sample, determining efficacy of cancer therapy, and determining response to and monitoring the efficacy of cancer therapy. |
| FILED | Thursday, November 05, 2015 |
| APPL NO | 14/933853 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/2818 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) Original (OR) Class G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275081 | Boyden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Edward S. Boyden (Chestnut Hill, Massachusetts); Katarzyna P. Adamala (Somerville, Massachusetts); Daniel Alberto Martin-Alarcon (Brookline, Massachusetts) |
| ABSTRACT | A programmable modular protein architecture for RNA binding comprises a set of modules, derived from RNA-binding protein Pumilio, that can be concatenated into chains of varying composition and length. When bound into a chain, each module has a preferred affinity for a specific RNA base. The chains can bind arbitrary RNA sequences with high specificity and fidelity by varying the sequence of modules within the chains. Each module contains at least 6 amino acids, with the amino acids in positions 1 and 5 providing the preferred affinity for the specific base, and the amino acid at position 2 serving as a stacking unit between concatenated modules. The modules may have four canonic forms, each having a preferred affinity for a different base and characterized by the base with which it has affinity, the two amino acids that provide the affinity, and the amino acid that serves as a stacking unit. |
| FILED | Tuesday, June 25, 2019 |
| APPL NO | 16/452362 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/47 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275132 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota); The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota); The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Wei Chen (Minneapolis, Minnesota); Byeong-Yeul Lee (Minneapolis, Minnesota); Xiao-Hong Zhu (Minneapolis, Minnesota); Hannes M. Wiesner (Minneapolis, Minnesota); Michael T. Lanagan (University Park, Pennsylvania); Qing X. Yang (University Park, Pennsylvania); Sebastian Rupprecht (University Park, Pennsylvania); Navid P. Gandji (University Park, Pennsylvania); Maryam Sarkarat (University Park, Pennsylvania) |
| ABSTRACT | An apparatus for transmitting and receiving radiofrequency (RF) signals in a magnetic resonance imaging system for proton and X-nuclear imaging includes at least one radiofrequency (RF) coil and an ultrahigh dielectric constant material incorporated within the at least one RF coil. The permittivity of the ultrahigh dielectric constant material depends on a temperature of the material and is tunable. The apparatus also includes a temperature controller that is thermally coupled to the ultrahigh dielectric constant material. The temperature controller is configured to control a temperature of the ultrahigh dielectric constant material to tune and optimize the permittivity of the ultrahigh dielectric constant material. A chemical structure and composition of the ultrahigh dielectric constant material is selected to control and optimize the permittivity and a dielectric loss of the ultrahigh dielectric constant material and a temperature dependence of the ultrahigh dielectric constant material. The apparatus provides denoising effect, high RF coil transmission and reception efficiencies, and improved signal-to-noise ratio for magnetic resonance or spectroscopic imaging applications and has a potential to advance clinical imaging for diagnosis. |
| FILED | Wednesday, April 08, 2020 |
| APPL NO | 16/843681 |
| ART UNIT | 2896 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/34 (20130101) G01R 33/543 (20130101) G01R 33/34007 (20130101) Original (OR) Class G01R 33/34015 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11276208 | Liang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for the State University of New York (Stony Brook, New York) |
| INVENTOR(S) | Jerome Zhengrong Liang (Stony Brook, New York); Yongfeng Gao (Ridge, New York); Yuxiang Xing (Stony Brook, New York); Hongbing Lu (Stony Brook, New York) |
| ABSTRACT | An exemplary system, method, and computer-accessible medium for generating computed tomography (“CT”) image(s) of a subject(s) can be provided which can include receiving low dose CT imaging information for the subject(s), where the low dose CT imaging information can be based on a radiation dose of less than about 50 mAs, receiving a priori CT image data, and generating the CT image(s) based on the low dose CT imaging information and the a priori CT image data. A further CT images(s) can be generated based on the CT image(s) and the a priori CT image data. The a priori CT image data can include a set of Markov Random Field (MRF) coefficients derived from high dose or full dose CT image data. |
| FILED | Tuesday, June 12, 2018 |
| APPL NO | 16/622162 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 11/006 (20130101) Original (OR) Class G06T 2207/10081 (20130101) G06T 2207/30008 (20130101) G06T 2207/30061 (20130101) G06T 2210/41 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11276478 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Xiao Wang (Chandler, Arizona); Qi Zhang (Tempe, Arizona); Fuqing Wu (Tempe, Arizona) |
| ABSTRACT | A method of tuning the performance of a synthetic gene circuit comprising a plurality of genes is disclosed. The method includes quantifying, for each gene, a relative gene expression metric. The metric is quantified by determining a number of nucleotides in a 5′ adjacent transcriptional region (ATR) of the gene, a number of nucleotides in a 3′ ATR, a minimum free energy of a mRNA secondary structure around a ribosome binding site of the gene, a total folding energy for the 5′ ATR, and a folding energy for the first 100 nucleotides of the 3′ ATR, and then summing sequence-dependent energy changes, the terms including scaling coefficients and an average energy cost for synthesizing a nucleotide. The method further includes simulating, through application of the relative gene expression metrics of the plurality of genes to a deterministic model, the performance of an intended function of the synthetic gene circuit. |
| FILED | Tuesday, January 15, 2019 |
| APPL NO | 16/248720 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/635 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) Original (OR) Class G16B 5/30 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11276500 | Styner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); The Royal Institution for the Advancement of Learning/McGill University (Montreal, Canada); College of Charleston (Charleston, South Carolina) |
| ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina); COLLEGE OF CHARLESTON (Charleston, South Carolina); THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (Montreal, Canada) |
| INVENTOR(S) | Martin Andreas Styner (Chapel Hill, North Carolina); Sun Hyung Kim (Durham, North Carolina); Donald Louis Collins (St-Lambert, Canada); Vladimir S. Fonov (Montreal, Canada); Brent Carl Munsell (Mount Pleasant, South Carolina); Joseph Piven (Pittsboro, North Carolina); Heather Cody Hazlett (Durham, North Carolina) |
| ABSTRACT | Methods, systems, and computer readable media for utilizing brain structural characteristics for predicting a diagnosis of a neurobehavioral disorder are disclosed. One method for utilizing brain structural characteristics for predicting a diagnosis of a neurobehavioral disorder includes receiving brain imaging data for a human subject of at least one first age. The method also includes determining, from the brain imaging data, measurements of brain structural characteristics of the human subject and inputting the brain structural characteristics into a model that predicts, using the measurements of the brain structural characteristics, a diagnosis of a neurobehavioral disorder at a second age greater than the at least one first age. |
| FILED | Friday, December 28, 2018 |
| APPL NO | 16/235379 |
| ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/4064 (20130101) A61B 5/4076 (20130101) A61B 5/7267 (20130101) A61B 2576/026 (20130101) Computer Systems Based on Specific Computational Models G06N 3/02 (20130101) G06N 3/084 (20130101) G06N 3/0454 (20130101) G06N 7/08 (20130101) G06N 20/10 (20190101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/20081 (20130101) G06T 2207/30016 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11272878 | Reed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | David A. Reed (Baltimore, Maryland); George C. Emmett (Wilmington, Delaware) |
| ABSTRACT | In an example, a method of detecting cyanide exposure of an individual comprises measuring a thiocyanate level of the individual, and comparing the measured thiocyanate level to a preset thiocyanate threshold to determine whether the measured thiocyanate level is above the preset thiocyanate threshold indicating a level of acute cyanide poisoning for which medical treatment is recommended to treat health effects of the exposure. |
| FILED | Friday, April 30, 2021 |
| APPL NO | 17/246283 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4845 (20130101) Original (OR) Class A61B 5/14551 (20130101) A61B 10/0051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11272956 | McDonnall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ripple, LLC (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel Allen McDonnall (Salt Lake City, Utah); Nathaniel Anthony Srok (Salt Lake City, Utah); Christopher Farand Smith (North Salt Lake, Utah) |
| ABSTRACT | Disclosed herein are systems and methods for insertion tools for implanting electrode leads. In one embodiment, an insertion tool comprises a shaft having an outer cannula and an inner cannula. An actuator may be configured to transition the insertion tool between at least three configurations. In a first configuration, the inner cannula and the outer cannula are configured to receive the lead in the shaft. In a second configuration, the inner cannula and the outer cannula are configured to secure the lead in the shaft. In a third configuration, the inner cannula and the outer cannula are configured to cause the lead to separate from the insertion tool and implant in adjacent tissue. |
| FILED | Sunday, March 17, 2019 |
| APPL NO | 16/355804 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/3421 (20130101) A61B 17/3468 (20130101) Original (OR) Class A61B 2017/00367 (20130101) A61B 2017/00438 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/72 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11273124 | Shukla et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| ASSIGNEE(S) | Brown University (Providence, Rhode Island) |
| INVENTOR(S) | Anita Shukla (Providence, Rhode Island); Sarah Cowles (Bedford, Massachusetts); Noel Vera-Gonzalez (San Juan, Puerto Rico); Christina Bailey-Hytholt (Millbury, Massachusetts); Eli Silvert (Woodbridge, Connecticut) |
| ABSTRACT | The invention provides functionalized antifungal-loaded liposomal formulations targeting Candida, which minimize damage to healthy human cells, limit antimicrobial exposure, and reduce the development of antifungal resistance. |
| FILED | Tuesday, March 24, 2020 |
| APPL NO | 16/828761 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) Original (OR) Class A61K 38/12 (20130101) A61K 47/14 (20130101) A61K 47/42 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11273574 | Kreiger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Megan A Kreiger (Champaign, Illinois); Michael Patrick Case (Mahomet, Illinois); Gerald R. Northrup (Champaign, Illinois); Ghassan Al-Chaar (Champaign, Illinois); Bruce A MacAllister (Mahomet, Illinois); William Jacob Wagner (Champaign, Illinois) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
| INVENTOR(S) | Megan A Kreiger (Champaign, Illinois); Michael Patrick Case (Mahomet, Illinois); Gerald R. Northrup (Champaign, Illinois); Ghassan Al-Chaar (Champaign, Illinois); Bruce A MacAllister (Mahomet, Illinois); William Jacob Wagner (Champaign, Illinois) |
| ABSTRACT | A scalable three dimensional printing apparatus capable of movement along three axes includes a tractor assembly movable along a selectively extendable rail component. Wheels in the tractor assembly surround part of the rail component to enable movement of a gantry bridge in a longitudinal direction along the rails. A movable printing trolley moves horizontally along a gantry bridge and has a printing column which can move vertically. Because the gantry bridge, trolley, and printing column move orthogonally to each other, users may print in three dimensions. Selective extension of the rails allows a user to alter lengthwise printing scale. |
| FILED | Monday, August 29, 2016 |
| APPL NO | 15/249739 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Original (OR) Class B28B 3/20 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) B29C 64/236 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 40/00 (20141201) Scaffolding; Forms; Shuttering; Building Implements or Aids, or Their Use; Handling Building Materials on the Site; Repairing, Breaking-up or Other Work on Existing Buildings E04G 21/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274066 | Goodman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Goodman Technologies LLC (Albuquerque, New Mexico); University of Hawai'i (Honolulu, Hawaii) |
| ASSIGNEE(S) | Goodman Technologies LLC (Albuquerque, New Mexico); University of Hawai'i (Honolulu, Hawaii) |
| INVENTOR(S) | William A. Goodman (Albuquerque, New Mexico); Mohammad Naghi Ghasemi-Nejhad (Honolulu, Hawaii); Brenden Masao Minei (Honolulu, Hawaii) |
| ABSTRACT | A method of making a ceramic matrix composite (CMC) part such as armor, in which a mixture, including a preceramic polymer, particles such as ceramic microparticles and/or nanoparticles, and organic compounds such as a surfactant and a solvent, are mixed to form a paste and printed or molded. The part is then cured and densified by polymer infiltration and pyrolysis (PIP) using the preceramic polymer with a varying amount and size of ceramic particles and different temperatures in some of the cycles. The CMC can contain silicon carbide, boron carbide, boron suboxide, alumina, or any other ceramic. The process is compatible with sacrificial materials, enabling the creation of parts with hollow portions or overhangs. The mixture preferably has a high loading of particles, for example between 70 wt % and 90 wt % of the mixture, in order to minimize shrinkage. Curing and pyrolyzing the part can be performed by microwaving. Two such CMC parts can be joined together by using the paste, having the same or a different concentration of particles, as an adhesive. |
| FILED | Thursday, November 29, 2018 |
| APPL NO | 16/203917 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/117 (20130101) C04B 35/563 (20130101) C04B 35/565 (20130101) C04B 35/587 (20130101) Original (OR) Class C04B 35/634 (20130101) C04B 35/6267 (20130101) C04B 2235/667 (20130101) C04B 2235/5418 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/0435 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274128 | Klapoetke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of the University of Alberta (Edmonton, Canada) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of the University of Alberta (Edmonton, Canada) |
| INVENTOR(S) | Nathan Klapoetke (Ashburn, Virginia); Brian Yichiun Chow (Cherry Hill, New Jersey); Edward Boyden (Chestnut Hill, Massachusetts); Gane Ka-Shu Wong (Edmonton, Canada); Yongku Peter Cho (Vernon, Connecticut) |
| ABSTRACT | The invention, in some aspects relates to compositions and methods for altering cell activity and function and the introduction and use of light-activated ion channels. |
| FILED | Thursday, May 28, 2020 |
| APPL NO | 16/885457 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 41/0023 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 2005/0661 (20130101) A61N 2005/0662 (20130101) Peptides C07K 14/405 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5041 (20130101) G01N 33/5058 (20130101) G01N 33/48728 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274137 | Slocik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Joseph M Slocik (Dayton, Ohio); Rajesh R. Naik (Centerville, Ohio); Patrick B Dennis (Cincinnati, Ohio) |
| ABSTRACT | A method comprising: providing aqueous insulin; titrating the aqueous insulin with a mixture of small molecule anions, e.g. D- and L-amino acid esters, small D- and L-peptide pairs, and DL lactate solution, to form an insulin/anion pair solution. Titrating may be performed until the insulin/anion pair solution becomes negative by zeta potential measurement. The insulin/anion pair solution may be dialyzed to remove excess anionic polymer using a membrane sufficient to separate the insulin/anion pairs from excess small molecule anions. The insulin/anion pair solution may be dialyzed or lyophilized to remove all of the water, forming a solid of ultra-stable insulin. The positive electrostatic charge of the aqueous insulin may be confirmed by measuring a positive zeta potential value. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/587611 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 1/14 (20130101) C07K 14/62 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274163 | Slocik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Joseph M Slocik (Dayton, Ohio); Rajesh R. Naik (Centerville, Ohio); Patrick B Dennis (Cincinnati, Ohio) |
| ABSTRACT | A method for creating an antibody ionic liquid, comprising: providing aqueous anti-A, anti-B, or anti-Rh antibodies; cationizing the aqueous antibodies by the addition of stoichiometric amounts of an excess of a positively-charged crosslinker in the presence of a coupling reagent; titrating the cationized antibodies with a counter anionic polymer to create at least one antibody cation/anion pair in aqueous solution until the antibody cation/anion pair solution becomes negative by zeta potential measurement. The method may further comprise lyophilizing the antibody cation/anion pair solution to remove all of the water, forming a lyophilized solid; and heating the lyophilized solid to generate a protein ionic liquid. Cationized antibodies may be purified of excess coupling reagents by dialysis in water by a membrane, and the antibody cation/anion solution may be dialyzed to remove excess anionic polymer with a similar membrane. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/587199 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274289 | Slocik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Joseph M Slocik (Dayton, Ohio); Rajesh R. Naik (Centerville, Ohio); Patrick B Dennis (Cincinnati, Ohio) |
| ABSTRACT | A method comprises the steps of: providing aqueous enzymes, wherein the enzymes are one of BamH1, EcoR1, EcoR2, and EcoRV; titrating the aqueous enzymes with a mixture of small molecule anions to form an enzyme/anion pair solution. Small molecule anions may comprise one or more of D- and L-amino acid esters, small D- and L-peptide pairs, and DL lactate solution. The titrating step is performed until the enzyme/anion pair solution becomes negative by zeta potential measurement. The at least one enzyme/anion pair may be dialyzed to remove excess anionic polymer using a dialysis membrane. The enzyme/anion pair solution is lyophilized to remove all of the water, forming a lyophilized solid of ultra-stable enzymes. Before titration, the positive electrostatic charge of the aqueous enzymes may be confirmed by measuring a positive zeta potential value. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/587154 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/96 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274293 | Funkner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CureVac Real Estate GmbH (Tübingen, Germany) |
| ASSIGNEE(S) | CureVac Real Estate GmbH (Tübingen, Germany) |
| INVENTOR(S) | Andreas Funkner (Tübingen, Germany); Stefanie Dorner (Tübingen, Germany); Stefanie Sewing (Tübingen, Germany); Johannes Kamm (Tübingen, Germany); Norbert Broghammer (Tübingen, Germany); Thomas Ketterer (Gomaringen, Germany); Thorsten Mutzke (Reutlingen, Germany) |
| ABSTRACT | The present invention relates to method for producing and purifying RNA comprising the steps of providing DNA encoding the RNA; transcription of the DNA into RNA; and conditioning and/or purifying of the solution comprising transcribed RNA by one or more steps of tangential flow filtration (TFF). |
| FILED | Tuesday, July 21, 2020 |
| APPL NO | 16/934279 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Separation B01D 61/145 (20130101) B01D 71/12 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1017 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/02 (20130101) G01N 2030/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274438 | Shields |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SELECT ENGINEERING SERVICES (Layton, Utah) |
| ASSIGNEE(S) | SELECT ENGINEERING SERVICES (Layton, Utah) |
| INVENTOR(S) | David Eugene Shields (Layton, Utah) |
| ABSTRACT | Rigid wall shelters are used throughout the world for shipping, living quarters, and housing for electronic systems and are energy inefficient. While investigating energy-efficient technologies for rigid wall shelters the discovery was made to insulate the outside of the shelter rather than the inside. Space is often limited inside of the shelter. The invention of an external, re-deployable insulation system was developed. The present invention is an insulating system composed of three main components. The first component is multiple, flexible envelopes filled with insulating materials (which creates a panel). The second component is multiple insulating strips that cover the joint between the panels. The final component is a weatherproof outer covering that protects the entire system from the elements. |
| FILED | Wednesday, September 16, 2020 |
| APPL NO | 17/023050 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/80 (20130101) E04B 1/86 (20130101) E04B 1/92 (20130101) E04B 1/762 (20130101) Original (OR) Class Finishing Work on Buildings, e.g Stairs, Floors E04F 13/002 (20130101) Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General E04H 1/1205 (20130101) E04H 2001/1283 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274904 | Dwyer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AimLock Inc. (Littleton, Colorado) |
| ASSIGNEE(S) | AIMLOCK INC. (Littleton, Colorado) |
| INVENTOR(S) | Benjamin Dwyer (Littleton, Colorado); Bryan Sterling Bockmon (Littleton, Colorado); Raymond Keeney (Littleton, Colorado); Jason R. Gallia (Littleton, Colorado); Shane Korthuis (Littleton, Colorado); Dusty Terry (Littleton, Colorado); Marc Hanchak (Littleton, Colorado) |
| ABSTRACT | A weapon mount for controlling targeting of a weapon includes a base, an arm that extends from the base, and an attachment component that is rotatably coupled with the arm. The base is attachable to a platform and is rotatable to control a yaw of the weapon relative to the platform. The attachment component is configured to couple with the weapon and is rotatable to control a pitch of the weapon relative to the platform. The arm is positioned relative to the base so that a recoil vector of the weapon is within 0.5 inches radially of an axis of rotation of the base. |
| FILED | Tuesday, August 25, 2020 |
| APPL NO | 17/002237 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 23/06 (20130101) F41A 23/52 (20130101) Weapon Sights; Aiming F41G 3/165 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274907 | Merems et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Paul A. Merems (Tucson, Arizona); Shane Olsen (Tucson, Arizona) |
| ABSTRACT | A nose or tail assembly for a flight vehicle is provided in which the deployment of the canards or fins is driven by energy imparted by the shroud when it is released. A tip section is rotatably coupled to a base, and both are stowed in a volume between the shroud and nose/tail assembly. As the shroud is released, a drive feature engages the tip section to rotate and join the base to form a complete canard or fin. This eliminates the need for storing the canards or fins in or wrapped around the body and eliminates the need for a complex deployment mechanism occupying an internal volume of the body. Although viable for all sizes of flight vehicles, the shroud-driven deployment system scales to very small diameter vehicles in which internal volume is not available to store either flight surfaces or deployment mechanisms. |
| FILED | Tuesday, April 28, 2020 |
| APPL NO | 16/860530 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274950 | Dardona et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Sameh Dardona (South Windsor, Connecticut); Callum Bailey (Glastonbury, Connecticut) |
| ABSTRACT | A sensor array having a lattice topology includes interconnects having an electrically-conductive layer sandwiched between two dielectric layers, the interconnects defining first-axis interconnects, second-axis interconnects, and interconnect junctions, sensor nodes located on associated interconnect junctions thereby defining an associated first-axis line and second-axis line, a sensor on an associated sensor node, a primary first-axis interconnect interface that is electrically connected to the first-axis interconnects, and a primary second-axis interconnect interface that is electrically connected to the second-axis interconnects. Each sensor node includes a first electrode that is electrically connected to an associated first-axis line, a second electrode that is electrically connected to an associated second-axis line, and a bypass bridge that electrically isolates the associated second-axis line from the associated first-axis line. |
| FILED | Monday, June 17, 2019 |
| APPL NO | 16/443056 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/16 (20130101) Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 21/02 (20130101) Original (OR) Class Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/16 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/16 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/0802 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275109 | Sita et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Richard Sita (Audubon, New Jersey); Michael G. Kane (Princeton, New Jersey) |
| ABSTRACT | Manufacturing integrated circuits is discussed with steps as follows. Creating a wafer with a plurality of dies, where each die contains its own integrated circuit. Fabricating multiple instances of TAP circuitry located in a margin between dies of the wafer. Fabricating on the wafer one row of test pads and power pads per group of dies on the wafer, where the row of test pads and power pads is electrically connected and shared among all of the dies in the group. The test and power pads connect to a chain of TAP circuitry in order to supply operating power as well as testing data to verify the integrity of each die in that group of dies. Singulating the dies to create each instance of the integrated circuit, and during the singulation process, the TAP circuitry located in the margin between the dies is destroyed. |
| FILED | Wednesday, March 07, 2018 |
| APPL NO | 16/490247 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/2822 (20130101) G01R 31/2884 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/78 (20130101) H01L 22/14 (20130101) H01L 22/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275168 | Sletten et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Mark A. Sletten (Takoma Park, Maryland); Hatim Alqadah (Aldie, Virginia) |
| ABSTRACT | Systems and methods are provided for morphological components analysis (MCA) techniques for efficient maritime target detection. Embodiments of the present disclosure provide systems, methods, and devices for determining the free parameter λ for MCA analysis. Embodiments of the present disclosure using MCA utilize effective pre-processing step(s) that separate target signals from clutter, thereby improving the overall performance of subsequent target detection processing. Systems and methods in accordance with embodiments of the present disclosure can optimize the value of the parameter λ, significantly affecting MCA performance. |
| FILED | Friday, December 28, 2018 |
| APPL NO | 16/235536 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/41 (20130101) G01S 7/414 (20130101) G01S 7/2955 (20130101) G01S 13/06 (20130101) G01S 13/449 (20130101) Original (OR) Class G01S 13/5244 (20130101) G01S 13/5248 (20130101) Electric Digital Data Processing G06F 17/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275208 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Linan Jiang (Tucson, Arizona); Stanley K. H. Pau (Tucson, Arizona); Robert A. Norwood (Tucson, Arizona) |
| ABSTRACT | A method of forming an optical interconnect between first and second photonic chips located on an optical printed circuit board includes applying a flexible, freestanding film onto the first and second chips so that the film extends over a gap and/or step between the chips. The film includes a photosensitive layer having a refractive index that decreases by exposure to radiation and a backing layer. The film is exposed to a flood exposure having a radiation dosage penetrating the backing layer and only a surface sublayer of the photosensitive layer. After curing the film, the backing layer is removed so that the photosensitive layer remains on the first and second chips. The photosensitive layer is selectively exposed to a second radiation dosage to define waveguide core(s) in unexposed regions of the photosensitive layer below the surface sublayer. The photosensitive layer is heated to cure the selectively exposed portions. |
| FILED | Tuesday, February 26, 2019 |
| APPL NO | 16/975819 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/00663 (20130101) Optical Elements, Systems, or Apparatus G02B 6/43 (20130101) G02B 6/138 (20130101) Original (OR) Class G02B 6/305 (20130101) G02B 6/428 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275644 | Biran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Giora Biran (Zichron-Yaakov, Israel); Pradip Bose (Yorktown Heights, New York); Alper Buyuktosunoglu (White Plains, New York); Pierce I-Jen Chuang (Briarcliff Manor, New York); Preetham M. Lobo (Bangalore, India); Ramon Bertran Monfort (New York, New York); Phillip John Restle (Katonah, New York); Christos Vezyrtzis (New Rochelle, New York); Tobias Webel (Schwaebisch Gmuend, Germany) |
| ABSTRACT | Techniques facilitating voltage droop reduction and/or mitigation in a processor core are provided. In one example, a system can comprise a memory that stores, and a processor that executes, computer executable components. The computer executable components can comprise an observation component that detects one or more events at a first stage of a processor pipeline. An event of the one or more events can be a defined event determined to increase a level of power consumed during a second stage of the processor pipeline. The computer executable components can also comprise an instruction component that applies a voltage droop mitigation countermeasure prior to the increase of the level of power consumed during the second stage of the processor pipeline and a feedback component that provides a notification to the instruction component that indicates a success or a failure of a result of the voltage droop mitigation countermeasure. |
| FILED | Friday, December 06, 2019 |
| APPL NO | 16/706195 |
| ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 1/28 (20130101) G06F 1/305 (20130101) G06F 1/324 (20130101) G06F 9/3836 (20130101) G06F 11/0721 (20130101) G06F 11/0793 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275711 | Telesca, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of Northern Arizona University (Flagstaff, Arizona); Government of the United States of America, as represented by the Secretary of the Airforce (Rome, New York) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY (Flagstaff, Arizona) |
| INVENTOR(S) | Donald A. Telesca, Jr. (Whitesboro, New York); Bertrand F Cambou (Flagstaff, Arizona); Paul G Flikkema (Flagstaff, Arizona) |
| ABSTRACT | Disclosed herein is a computing system with the capability to execute instructions in different positional notation values. The definition of a positional notation value is given by the general formula that represent a base 10 numeral in any positional notation in the following manner: . . . d3r3+d2r2+d1r1+d0r0, where d is a coefficient, r is the base of the positional number system (i.e. r=2 for binary, or r=3 for ternary), and the exponent is the position of the digit. The computing may provide a configuration which hybridizes the instructions of multiple positional notation values in variable ratios. The computing system may dynamically switch between the multiple hybridized instructions sets. Embodiments may be applied to provide security benefits. |
| FILED | Tuesday, April 07, 2020 |
| APPL NO | 16/842643 |
| ART UNIT | 2192 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 8/41 (20130101) G06F 9/4411 (20130101) G06F 9/44505 (20130101) G06F 9/45545 (20130101) G06F 15/7871 (20130101) Original (OR) Class G06F 21/52 (20130101) G06F 21/6227 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0618 (20130101) H04L 9/0643 (20130101) H04L 9/0822 (20130101) H04L 9/3073 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275712 | Tschirhart et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northrop Grumman Systems Corporation (Falls Church, Virginia) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Paul Kenton Tschirhart (Odenton, Maryland); Brian Konigsburg (Pasadena, Maryland) |
| ABSTRACT | In an embodiment, a method for processing data in a single instruction multiple data (SIMD) computer architecture is provided. A processing element (PE) may determine based on a masking instruction, a predication state indicative of one of a conditional predication mode and an absolute predication mode. The PE may receive a predicated instruction and, based on a value of a head bit of the bits of a predication mask and on the value indicative of the predication state whether to commit a computation corresponding to execution of the predicated instruction. In another embodiment, a SIMD controller stores loops and sections of a program as a separate instruction stream record for generating the memory address of the next instruction. For data streams, the SIMD controller records information for each data memory access that references the same register files that are used by the instruction streams. |
| FILED | Thursday, August 20, 2020 |
| APPL NO | 16/998186 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3887 (20130101) G06F 9/30018 (20130101) G06F 9/30101 (20130101) G06F 9/30185 (20130101) G06F 15/8007 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275777 | Ackermann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Christopher Ackermann (Fairfax, Virginia); Charles Beller (Baltimore, Maryland); Michael Drzewucki (Woodbridge, Virginia) |
| ABSTRACT | Embodiments for generating a timeline associated with an entity are provided. A plurality of events referenced in a corpus are identified. Each of the plurality of events is associated with an entity. An event time is determined for each of the plurality of events based on information associated with at least one reference to the respective event within the corpus. A score is calculated for each of the plurality of events based on at least one of a number of references to the respective event within the corpus and information associated with a user. A timeline for at least some of the plurality of events is generated based on the calculated scores of the plurality of events and the determined event time for each of the plurality of events. |
| FILED | Thursday, August 22, 2019 |
| APPL NO | 16/548110 |
| ART UNIT | 2168 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/332 (20190101) G06F 16/338 (20190101) G06F 16/383 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275868 | Geis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute Of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael W. Geis (Acton, Massachusetts); Joshua Kramer (Branchburg, New Jersey); Karen M. G. V. Gettings (Carlisle, Massachusetts); Marc J. Burke (Pelham, New Hampshire); Mankuan M. Vai (Sudbury, Massachusetts); Theodore M. Lyszczarz (Concord, Massachusetts) |
| ABSTRACT | An improved waveguide is disclosed. The waveguide utilizes a luminescent material disposed within or around its perimeter to introduce additional light into the waveguide. For example, the waveguide may include a plurality of planar layers having different refractive indexes. A luminescent material may be disposed along the outer edge of these layers. When light from within the waveguide strikes the luminescent material, it emits light, thereby adding to the light in the waveguide. Not only does the luminescent material introduce more light into the waveguide, it also introduces more light sources, thereby making it more difficult to introduce a probe without blocking at least a portion of the light destined for the image sensor. The luminescent material may be a phosphor. |
| FILED | Wednesday, July 01, 2020 |
| APPL NO | 16/917964 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/0003 (20130101) G02B 6/43 (20130101) G02B 6/4214 (20130101) G02B 6/4215 (20130101) G02B 6/4295 (20130101) G02B 6/4298 (20130101) Electric Digital Data Processing G06F 21/70 (20130101) Original (OR) Class G06F 21/72 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00577 (20130101) G06K 2009/0059 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/04 (20130101) H04L 63/162 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275881 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cadence Design Systems, Inc. (San Jose, California) |
| ASSIGNEE(S) | Cadence Design Systems, Inc. (San Jose, California) |
| INVENTOR(S) | Weifu Li (San Jose, California); Elias Lee Fallon (Allison Park, Pennsylvania); Supriya Ananthram (Los Gatos, California); Weiyi Qi (Santa Clara, California); Sheng Qian (Sunnyvale, California) |
| ABSTRACT | The present disclosure relates to a computer-implemented method for electronic design is provided. Embodiments may include receiving, using at least one processor, an electronic design having one or more unoptimized nets. Embodiments may further include applying a genetic algorithm to the electronic design, wherein the genetic algorithm includes a multi-stage routing analysis. A first stage analysis may apply a device-level global routing analysis, a second stage analysis may include an intra-row routing analysis, a third stage may include an inter-row routing analysis, and a fourth stage may include a post-routing optimization analysis. Embodiments may also include generating an optimized routing of the one or more unoptimized nets and displaying the optimized routing at a graphical user interface. |
| FILED | Monday, January 04, 2021 |
| APPL NO | 17/140510 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Electric Digital Data Processing G06F 30/31 (20200101) G06F 30/398 (20200101) G06F 30/3947 (20200101) Original (OR) Class G06F 2111/06 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275882 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cadence Design Systems, Inc. (San Jose, California) |
| ASSIGNEE(S) | Cadence Design Systems, Inc. (San Jose, California) |
| INVENTOR(S) | Wangyang Zhang (Allison Park, Pennsylvania); Elias Lee Fallon (Allison Park, Pennsylvania); Regis R. Colwell (Gibsonia, Pennsylvania); Hua Luo (Pittsburgh, Pennsylvania); Namita Bhushan Rane (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present disclosure relates to a computer-implemented method for electronic design is provided. Embodiments may include receiving, using at least one processor, an electronic design schematic and an electronic design layout and analyzing, via machine learning, at least one schematic feature from a pair of devices associated with the electronic design schematic. Embodiments may further include determining, based, at least in part, upon the analyzing, whether the pair of devices should be grouped together. |
| FILED | Friday, July 26, 2019 |
| APPL NO | 16/523112 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Electric Digital Data Processing G06F 30/398 (20200101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6282 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275977 | Miklos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Combat Capabilities Development Command, Chemical Biological Center (Apg, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Aleksandr E Miklos (Baldwin, Maryland); Gary K Kilper (Edgewood, Maryland); Charles E Davidson (Towson, Maryland); Christian J Whitchurch (Los Gatos, California) |
| ABSTRACT | A system and method for on-demand production of custom indicator assays including a computing device for receiving a user specified analyte for which the assay will test, a database accessible via the computing device and containing indicator response data for a variety of analytes and potential interferents, and a printer operably connected to the computing device for printing an optimized combination of indicators onto a substrate based on the indicator response data of the database for a user specified analyte and any user specified potential interferents. The method includes receiving in a user interface at least one user specified analyte; querying the database to determine an optimized combination of indicators to test for the at least one user specified analyte; and printing from a printer the optimized combination of indicators onto a substrate. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/150515 |
| ART UNIT | 2674 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) Electric Digital Data Processing G06F 3/0482 (20130101) G06F 16/22 (20190101) G06F 16/245 (20190101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 15/021 (20130101) Original (OR) Class G06K 15/102 (20130101) G06K 15/1803 (20130101) G06K 15/1823 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11276728 | Heron et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); Cornell University (Ithaca, New York) |
| INVENTOR(S) | John Thomas Heron (Saline, Michigan); Peter Benjamin Meisenheimer (Ann Arbor, Michigan); Darrell G. Schlom (Ithaca, New York); Rachel Steinhardt (Brooktondale, New York) |
| ABSTRACT | A heterostructure includes a substrate exhibiting a piezoelectric effect, and a magnetostrictive film supported by the substrate. The magnetostrictive film includes an iron-gallium alloy. The iron-gallium alloy has a gallium composition greater than 20%. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 16/784351 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/20 (20130101) Original (OR) Class H01L 41/09 (20130101) H01L 41/20 (20130101) H01L 41/47 (20130101) H01L 41/125 (20130101) H01L 41/1875 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11276880 | Smirnova et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | South Dakota Board of Regents (Pierre, South Dakota) |
| ASSIGNEE(S) | South Dakota Board of Regents (Pierre, South Dakota) |
| INVENTOR(S) | Alevtina Smirnova (Rapid City, South Dakota); Matthew Dondelinger (Rapid City, South Dakota); Joel Swanson (Rapid City, South Dakota) |
| ABSTRACT | The present disclosure relates to a manufacturing process of the solid-state glass-ceramic electrolytes, known in the art as antiperovskites. Specifically, the disclosure is focused on manufacturing of the solid-state electrolyte from the corresponding precursors directly on the active electrode surface of an electrochemical device, specifically anode or cathode of the lithium-ion or lithium metal batteries. |
| FILED | Tuesday, October 01, 2019 |
| APPL NO | 16/589429 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/661 (20130101) H01M 10/052 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2004/027 (20130101) H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11277419 | Crouch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Amida Technology Solutions, Inc. (Washinton, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alfred Larry Crouch (Cedar Park, Texas); Peter Lawrence Levin (Silver Springs, Maryland); John David Akin (Plano, Texas); Adam Wade Ley (Allen, Texas); Matthew McKinnon Ritonia (Arlington, Virginia); Wesley Layton Ellington (Dallas, Texas); Maria Anne Spasojevic (Palo Alto, California) |
| ABSTRACT | A method and system for analysis of a facility may include providing an emulation host system, generating a pristine circuit model on the emulation host system, inserting a first hardware trojan model, emulating operation of the golden circuit model, and emulating operation of the first hardware trojan model, and determine a set of machine-learning models, detecting the presence of an unknown trojan as a function of the set of machine learning models and using the same to authenticate the integrity of a GPS signal. |
| FILED | Sunday, December 27, 2020 |
| APPL NO | 17/134441 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/23 (20130101) G01S 19/42 (20130101) Electric Digital Data Processing G06F 16/2379 (20190101) Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11277430 | Vela et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Booz Allen Hamilton Inc. (McLean, Virginia) |
| ASSIGNEE(S) | BOOZ ALLEN HAMILTON INC. (McLean, Virginia) |
| INVENTOR(S) | Chelsea Vela (San Antonio, Texas); Justin Hoffman (Boerne, Texas) |
| ABSTRACT | A system for generating a cyber-attack to penetrate a network. The system includes an identification module configured to identify at least one vulnerability of the network by examining at least one of a node of the network, data transmission within the network, or data received from a cyber defense mechanism; a generation module configured to generate a cyber-attack based on the at least one vulnerability of the network, and a goal to be achieved by the cyber-attack. The system includes a penetration module configured to penetrate the network with the cyber-attack and determine an effectiveness rating of the penetration; and a feedback module configured to provide a feedback to the identification module based on at least the effectiveness rating of the penetration. |
| FILED | Wednesday, June 26, 2019 |
| APPL NO | 16/453212 |
| ART UNIT | 2496 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) H04L 63/1433 (20130101) Original (OR) Class H04L 63/1466 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11273124 | Shukla et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| ASSIGNEE(S) | Brown University (Providence, Rhode Island) |
| INVENTOR(S) | Anita Shukla (Providence, Rhode Island); Sarah Cowles (Bedford, Massachusetts); Noel Vera-Gonzalez (San Juan, Puerto Rico); Christina Bailey-Hytholt (Millbury, Massachusetts); Eli Silvert (Woodbridge, Connecticut) |
| ABSTRACT | The invention provides functionalized antifungal-loaded liposomal formulations targeting Candida, which minimize damage to healthy human cells, limit antimicrobial exposure, and reduce the development of antifungal resistance. |
| FILED | Tuesday, March 24, 2020 |
| APPL NO | 16/828761 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) Original (OR) Class A61K 38/12 (20130101) A61K 47/14 (20130101) A61K 47/42 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11273236 | Alsberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); Worcester Polytechnic Institute (Worcester, Massachusetts) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); WORCESTER POLYTECHNIC INSTITUTE (Worcester, Massachusetts) |
| INVENTOR(S) | Eben Alsberg (Cleveland, Ohio); Anna D. Dikina (Mentor, Ohio); Marsha W. Rolle (Worcester, Massachusetts); Hannah A. Strobel (Marlborough, Massachusetts) |
| ABSTRACT | A modular engineered tissue construct includes a plurality of fused self-assembled, scaffold-free, high-density cell aggregates. At least one cell aggregate includes a plurality of cells and a plurality of biocompatible and biodegradable nanoparticles and/or microparticles that are incorporated within the cell aggregates. The nanoparticles and/or microparticles acting as a bulking agent within the cell aggregate to increase the cell aggregate size and/or thickness and improve the mechanical properties of the cell aggregate as well as to deliver bioactive agents. |
| FILED | Thursday, September 07, 2017 |
| APPL NO | 15/698429 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 35/32 (20130101) A61K 35/42 (20130101) A61K 35/44 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 27/58 (20130101) A61L 27/3804 (20130101) A61L 27/3817 (20130101) Original (OR) Class A61L 27/3839 (20130101) A61L 27/3886 (20130101) A61L 2300/62 (20130101) A61L 2300/414 (20130101) A61L 2400/12 (20130101) A61L 2430/02 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 25/14 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0655 (20130101) C12N 5/0697 (20130101) C12N 2533/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11273329 | Konofagou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Elisa E. Konofagou (New York, New York); Fabrice Marquet (New York, New York); Yao-Sheng Tung (New York, New York) |
| ABSTRACT | Systems and methods for cavitation-guided opening of a targeted region of tissue within a primate skull are provided. In one example, a method includes delivering one or more microbubbles to proximate the targeted region, applying an ultrasound beam, using a transducer, through the skull of the primate to the targeted region to open the tissue, transcranially acquiring acoustic emissions produced from an interaction between the one or more microbubbles and the tissue, and determining a cavitation spectrum from the acquired acoustic emissions. |
| FILED | Wednesday, September 18, 2019 |
| APPL NO | 16/575044 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/481 (20130101) A61B 8/0808 (20130101) A61B 17/2258 (20130101) A61B 90/10 (20160201) A61B 2017/00106 (20130101) A61B 2017/22008 (20130101) A61B 2017/22089 (20130101) A61B 2090/378 (20160201) A61B 2503/40 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class A61N 2007/0039 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11273432 | Trovitch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ryan J. Trovitch (Phoenix, Arizona); Thu Thao Nguyen (Tempe, Arizona); Tufan K. Mukhopadhyay (Tempe, Arizona); Brian M. Glazier (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Ryan J. Trovitch (Phoenix, Arizona); Thu Thao Nguyen (Tempe, Arizona); Tufan K. Mukhopadhyay (Tempe, Arizona); Brian M. Glazier (Tempe, Arizona) |
| ABSTRACT | The synthesis and structure of beta-diketiminate manganese compounds are described, as well as their use as catalysts for the hydrosilylation and hydroboration of unsaturated organic compounds and main group element-main group element bond formation via dehydrogenative coupling. |
| FILED | Thursday, May 09, 2019 |
| APPL NO | 16/407317 |
| ART UNIT | 1738 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/32 (20130101) B01J 31/1815 (20130101) Original (OR) Class B01J 2231/323 (20130101) B01J 2531/72 (20130101) B01J 2531/0216 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 47/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 77/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11273473 | Quigley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts); Nicole Neff (Colorado Springs, Colorado); Jack Rowbottom (Swansea, Massachusetts) |
| ABSTRACT | A control system for controlling extraction of landfill gas from a landfill via a gas extraction system, the gas extraction system comprising well piping for coupling a plurality of wells to a gas output. The control system comprises a controller configured to: obtain a value indicating measured energy content of landfill gas collected at the gas output from the plurality of wells; determine whether the measured energy content is different from a target energy content; and in response to determining that the measured energy content is different from the target energy content: control a plurality of valves disposed in the well piping to change flow rates of landfill gas being extracted from at least some of the plurality of wells at least in part by changing degrees to which the plurality of valves are open. |
| FILED | Monday, June 15, 2020 |
| APPL NO | 16/901430 |
| ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 34/02 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/30 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11273494 | Humphrey |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Simon M. Humphrey (Lakeway, Texas) |
| ABSTRACT | Disclosed herein are methods of making a plurality of metal particles, the methods comprising: injecting a metal particle precursor, a capping material, and a reducing agent into an inlet of a continuous flow microwave reactor, thereby forming a mixture within the continuous flow microwave reactor, wherein the inlet of the continuous flow microwave reactor is fluidly connected to an outlet of the continuous flow microwave reactor through a reaction vessel; flowing the mixture through the reaction vessel, wherein the metal particle precursor is reduced within the reaction vessel, thereby forming the plurality of metal particles; and collecting the plurality of metal particles from the outlet of the continuous flow microwave reactor. |
| FILED | Friday, March 16, 2018 |
| APPL NO | 16/494800 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/08 (20130101) B01J 23/464 (20130101) B01J 37/04 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0018 (20130101) B22F 9/24 (20130101) Original (OR) Class B22F 2202/11 (20130101) B22F 2301/25 (20130101) B22F 2302/45 (20130101) B22F 2303/01 (20130101) B22F 2304/054 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274120 | Chialvo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of The University of Alabama (Tusclaoosa, Alabama) |
| ASSIGNEE(S) | The Board of Trustees of The University of Alabama (Tuscaloosa, Alabama) |
| INVENTOR(S) | Clare Scott Chialvo (Banner Elk, North Carolina); Lukasz Ciesla (Northport, Alabama) |
| ABSTRACT | Methods for extracting metabolites from mushroom comprising dispersing a sample of the mushroom; contacting the sample with a first solvent system at a temperature of 80° C. or greater to extract at least a first portion of metabolites from the sample; and contacting the sample with a second solvent system at a temperature of 80° C. or greater to extract at least a second portion of metabolites from the sample, wherein the combined first portion of metabolites and the second portion of metabolites include primary and secondary metabolites from the mushroom. A high-throughput process for establishing a metabolic profile of a mushroom, such as Amanita mushroom, can comprise extracting metabolites from mushroom and analyzing the extracted metabolites by automatic peak recognition or peak integration. Assay for identifying and/or assessing candidate metabolites extracted from Amanita mushroom are also disclosed. |
| FILED | Thursday, June 18, 2020 |
| APPL NO | 16/905090 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 1/145 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274128 | Klapoetke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of the University of Alberta (Edmonton, Canada) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of the University of Alberta (Edmonton, Canada) |
| INVENTOR(S) | Nathan Klapoetke (Ashburn, Virginia); Brian Yichiun Chow (Cherry Hill, New Jersey); Edward Boyden (Chestnut Hill, Massachusetts); Gane Ka-Shu Wong (Edmonton, Canada); Yongku Peter Cho (Vernon, Connecticut) |
| ABSTRACT | The invention, in some aspects relates to compositions and methods for altering cell activity and function and the introduction and use of light-activated ion channels. |
| FILED | Thursday, May 28, 2020 |
| APPL NO | 16/885457 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 41/0023 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 2005/0661 (20130101) A61N 2005/0662 (20130101) Peptides C07K 14/405 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5041 (20130101) G01N 33/5058 (20130101) G01N 33/48728 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274294 | Voytas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); Iowa State University Research Foundation Inc. (Ames, Iowa) |
| INVENTOR(S) | Daniel F. Voytas (Falcon Heights, Minnesota); Adam J. Bogdanove (Ithaca, New York); Feng Zhang (Maple Grove, Minnesota) |
| ABSTRACT | Materials and methods related to gene targeting (e.g., gene targeting with transcription activator-like effector nucleases; “TALENS”) are provided. |
| FILED | Wednesday, August 28, 2019 |
| APPL NO | 16/553550 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0022 (20130101) C12N 9/22 (20130101) C12N 15/01 (20130101) C12N 15/62 (20130101) C12N 15/63 (20130101) C12N 15/102 (20130101) Original (OR) Class C12N 15/907 (20130101) C12N 15/8213 (20130101) C12N 2810/85 (20130101) Enzymes C12Y 301/21004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274323 | Kavazanjian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Edward Kavazanjian (Tempe, Arizona); Nasser Hamdan (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Edward Kavazanjian (Tempe, Arizona); Nasser Hamdan (Scottsdale, Arizona) |
| ABSTRACT | The present invention provides methods for mineral precipitation and/or cementation of permeable or fractured non-porous materials using isolated urease. |
| FILED | Wednesday, February 05, 2020 |
| APPL NO | 16/782361 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 11/00 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 28/10 (20130101) C04B 28/10 (20130101) C04B 2103/0001 (20130101) C04B 2103/0001 (20130101) C04B 2111/72 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/80 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 3/00 (20130101) C12P 9/00 (20130101) Original (OR) Class Enzymes C12Y 305/01005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274329 | Ramasamy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| INVENTOR(S) | Ramaraja P. Ramasamy (Watkinsville, Georgia); Yi Fang (Athens, Georgia) |
| ABSTRACT | Provided herein are plant/plant pathogen volatile compound electrochemical sensors, plant/plant pathogen volatile detection systems, and methods for detecting stress-induced plant volatile compounds and/or a plant-pathogen emitted volatile compounds. |
| FILED | Wednesday, December 11, 2019 |
| APPL NO | 16/710059 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 9/26 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/005 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3277 (20130101) G01N 27/3278 (20130101) G01N 33/025 (20130101) G01N 33/0047 (20130101) G01N 33/0098 (20130101) G01N 33/483 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274915 | Pau et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Stanley Pau (Tucson, Arizona); Rongguang Liang (Tucson, Arizona) |
| ABSTRACT | Methods, devices and systems are described that use a combination multiple light sources having different coherence lengths to measure surface characteristics of an object. One example system includes a two laser sources configured to operate at a first and a second center wavelength, a broadband source configured to operate at a range of wavelengths outside of the operating range of the at least two lasers, a phase mask array and a color filter arranged, respectively, to impart different phase delays and provide spectral filtering corresponding to the emitted radiation from the sources. A pixelated sensor device is positioned to simultaneously measure intensity values associated with a plurality of interferograms formed due to interference of light from the light sources after propagation through the phase mask array and the color filter. The measured intensity values enable the determination of surface characteristics of the object. |
| FILED | Monday, April 29, 2019 |
| APPL NO | 17/052448 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02007 (20130101) G01B 9/02041 (20130101) Original (OR) Class G01B 11/24 (20130101) G01B 11/30 (20130101) Optical Elements, Systems, or Apparatus G02B 5/201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275007 | Agarwal et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arvind Agarwal (Miami, Florida); Kazue Orikasa (Miami, Florida); Nicole Bacca (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Arvind Agarwal (Miami, Florida); Kazue Orikasa (Miami, Florida); Nicole Bacca (Miami, Florida) |
| ABSTRACT | Systems and methods for accurate characterization of the mechanical properties of ultra-soft materials in the meso/macro-length scale are provided. Through the use of a millimeter-scale, ultra-high molecular weight indenter probe, accurate mechanical characterization of ultra-soft materials on the centimeter-scale can be achieved. The indenter probe can capture the adhesion forces present during the approach and detachment segments of the indentation process. |
| FILED | Thursday, January 28, 2021 |
| APPL NO | 17/160596 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/42 (20130101) Original (OR) Class G01N 2203/0078 (20130101) G01N 2203/0286 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/366 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275031 | Ryckman et al. |
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| FUNDED BY |
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| APPLICANT(S) | CLEMSON UNIVERSITY (Clemson, South Carolina) |
| ASSIGNEE(S) | Clemson University (Clemson, South Carolina) |
| INVENTOR(S) | Judson Ryckman (Clemson, South Carolina); Gabriel Allen (Clemson, South Carolina); William Frederick Delaney (Clemson, South Carolina); Tahmid Talukdar (Clemson, South Carolina) |
| ABSTRACT | Devices and methods of providing a high-performance optical sensor disclose a sensor comprised of a porous material designed to have a multilayer rib-type or multilayer pillar-type waveguide geometry. The resulting porous nanomaterial multilayer-rib or multilayer-pillar waveguide design is optically capable of achieving ˜100% confinement factor while maintaining small mode area and single-mode character. Fabrication of the device is enabled by an inverse processing technique, wherein silicon wafers are first patterned and etched through well-established techniques, which allows porous nanomaterial synthesis (i.e., porous silicon anodization) either at the wafer-scale or at the chip-scale after wafer dicing. While ˜100% is an optimal target, typical devices per presently disclosed subject matter may operate with ˜98-99+%, while allowing for some design adjustments to be made if necessary, and still maintaining high sensitivity. i.e., >85-90% confinement suitable in some applications. In those instances, a primary benefit would still be use of the presently disclosed fabrication technology. |
| FILED | Thursday, September 05, 2019 |
| APPL NO | 16/561093 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/7746 (20130101) Original (OR) Class G01N 2021/7779 (20130101) Optical Elements, Systems, or Apparatus G02B 6/136 (20130101) G02B 6/1225 (20130101) G02B 2006/12061 (20130101) G02B 2006/12097 (20130101) G02B 2006/12107 (20130101) G02B 2006/12138 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275071 | Schwabacher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UWM Research Foundation, Inc. (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | UWM Research Foundation, Inc. (Milwaukee, Wisconsin) |
| INVENTOR(S) | Alan Schwabacher (Shorewood, Wisconsin); Peter Geissinger (Shorewood, Wisconsin); Trevor Hagemann (Milwaukee, Wisconsin); Sarah Oehm (Milwaukee, Wisconsin); Tyler G. Fenske (Milwaukee, Wisconsin) |
| ABSTRACT | Sensors for detecting and distinguishing metals in a sample comprise phenol group-containing azo dyes, the phenol group having one hydroxy involved in reversible metal ion binding and a second hydroxy alkylated to an optically transparent substrate. The sensors have utility for detecting chromium, calcium, magnesium, copper, mercury, nickel, zinc, cobalt, manganese, cadmium, lead, tin, aluminum, potassium, sodium, or arsenic ions in a sample. |
| FILED | Friday, October 14, 2016 |
| APPL NO | 15/767175 |
| ART UNIT | 1796 — Optics |
| CURRENT CPC | Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 29/0048 (20130101) C09B 29/3621 (20130101) C09B 29/3643 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) G01N 21/643 (20130101) G01N 33/1813 (20130101) Original (OR) Class G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275563 | Najafi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Mohammadhassan Najafi (Lafayette, Louisiana); David J. Lilja (Lake Elmo, Minnesota); Marcus Riedel (Shorewood, Minnesota); Kiarash Bazargan (Plymouth, Minnesota); Sayed Abdolrasoul Faraji (Minneapolis, Minnesota); Bingzhe Li (Falcon Heights, Minnesota) |
| ABSTRACT | Example devices are described that include a computational unit configured to process first set of data bits encoding a first numerical value and a second set of data bits encoding a second numerical value. The computational unit includes a bit-stream generator configured to generate bit combinations representing first and second bit sequences that encode the first and second numerical values, respectively, based on a proportion of the data bits in the sequence that are high relative to the total data bits. The first bit sequence is generated using a first Sobol sequence source, and the second bit sequence is generated using a second Sobol sequence source different from the first Sobol sequence source. The device also includes computation logic configured to perform a computational operation on the bit combinations and produce an output bit-stream having a set of data bits indicating a result of the computational operation. |
| FILED | Friday, June 19, 2020 |
| APPL NO | 16/906122 |
| ART UNIT | 2182 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 7/70 (20130101) G06F 7/582 (20130101) Original (OR) Class Pulse Technique H03K 3/84 (20130101) Coding; Decoding; Code Conversion in General H03M 7/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275941 | Papanikolopoulos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Nikolaos Papanikolopoulos (Minneapolis, Minnesota); Vassilios Morellas (Plymouth, Minnesota); Dimitris Zermas (Minnetonka, Minnesota); David Mulla (Brooklyn Center, Minnesota); Mike Bazakos (Bloomington, Minnesota) |
| ABSTRACT | Systems, techniques, and devices for detecting plant biometrics, for example, plants in a crop field. An imaging device of an unmanned vehicle may be used to generate a plurality of images of the plants, and the plurality of images may be used to generate a 3D model of the plants. The 3D model may define locations and orientations of leaves and stems of plants. The 3D model may be used to determine at least one biometric parameter of at least one plant in the crop. Such detection of plant biometrics may facilitate the automation of crop monitoring and treatment. |
| FILED | Friday, March 08, 2019 |
| APPL NO | 16/296941 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 2/00 (20180201) A01G 7/00 (20130101) Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/127 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 47/08 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00657 (20130101) Original (OR) Class G06K 9/00885 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/02 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 17/00 (20130101) G06T 2200/04 (20130101) G06T 2207/10028 (20130101) G06T 2207/10032 (20130101) G06T 2207/30188 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11276478 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Xiao Wang (Chandler, Arizona); Qi Zhang (Tempe, Arizona); Fuqing Wu (Tempe, Arizona) |
| ABSTRACT | A method of tuning the performance of a synthetic gene circuit comprising a plurality of genes is disclosed. The method includes quantifying, for each gene, a relative gene expression metric. The metric is quantified by determining a number of nucleotides in a 5′ adjacent transcriptional region (ATR) of the gene, a number of nucleotides in a 3′ ATR, a minimum free energy of a mRNA secondary structure around a ribosome binding site of the gene, a total folding energy for the 5′ ATR, and a folding energy for the first 100 nucleotides of the 3′ ATR, and then summing sequence-dependent energy changes, the terms including scaling coefficients and an average energy cost for synthesizing a nucleotide. The method further includes simulating, through application of the relative gene expression metrics of the plurality of genes to a deterministic model, the performance of an intended function of the synthetic gene circuit. |
| FILED | Tuesday, January 15, 2019 |
| APPL NO | 16/248720 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/635 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) Original (OR) Class G16B 5/30 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11277127 | Mantooth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | H. Alan Mantooth (Fayetteville, Arkansas); Shuang Zhao (Gardena, California); Audrey Dearien (Dallas, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | H. Alan Mantooth (Fayetteville, Arkansas); Shuang Zhao (Gardena, California); Audrey Dearien (Dallas, Texas) |
| ABSTRACT | An improved gate driver using a microcontroller (uC), a voltage selector (VS), an adjustable voltage regulator (AVR), and an auxiliary current sinking circuit (ACSC) to actively provide selectable drive signals either higher, lower or equal to the basic on voltage and off voltage drive signals for a selected semiconductor device thereby providing an active voltage-mode gate driver for actively speeding up or slowing both the on time and off time transitions of a semiconductor. |
| FILED | Friday, May 15, 2020 |
| APPL NO | 16/875029 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Systems for Regulating Electric or Magnetic Variables G05F 1/575 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/483 (20130101) Pulse Technique H03K 17/161 (20130101) H03K 17/567 (20130101) H03K 17/693 (20130101) H03K 17/04206 (20130101) H03K 17/6871 (20130101) Original (OR) Class H03K 2217/0036 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11272875 | Arnold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | KNOW BIOLOGICAL, INC. (Milton, Georgia); National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Know Biological, Inc. (Milton, Georgia); National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Gary Stephen Arnold (Cumming, Georgia); Matthew Wallace Moorman (Albuquerque, New Mexico); Joshua Jonathan Whiting (Albuquerque, New Mexico) |
| ABSTRACT | A volatile organic compound collector can include a collector material configured to collect volatile organic compounds given off from a patient's skin; a wrapping configured to isolate the collector material from an external environment; a heater comprising a heating element, the heating element configured to emit a thermal pulse to desorb the volatile organic compounds from the collector material; and a mesh layer configured to prevent the collector material from contacting the patient's skin, wherein the collector material is received between the wrapping and the mesh layer. |
| FILED | Wednesday, April 28, 2021 |
| APPL NO | 17/242441 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/443 (20130101) A61B 5/4094 (20130101) Original (OR) Class A61B 5/6831 (20130101) A61B 5/6833 (20130101) A61B 10/00 (20130101) A61B 2010/0083 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/00 (20130101) G01N 30/20 (20130101) G01N 30/64 (20130101) G01N 30/80 (20130101) G01N 2030/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11273526 | Johnson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kyle William Johnson (Rapid City, South Dakota); Jamie Walter Beard (Cookeville, Tennessee); Bhaarat Kumar Jasthi (Rapid City, South Dakota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kyle William Johnson (Rapid City, South Dakota); Jamie Walter Beard (Cookeville, Tennessee); Bhaarat Kumar Jasthi (Rapid City, South Dakota) |
| ABSTRACT | Systems and methods for application of stress corrosion cracking resistant cold spray coatings include a method of forming a partial coating on a canister having a perimeter wall with a surface. The method may include identifying a compromised region on the surface of the wall of the canister, and impacting a substantially linear flow of particles of a powder against an area in the compromised region of the surface in a manner effective to cause the particles of the powder to bond to the surface of the wall to produce a coating on the area of the compromised region. The method may also include moving the substantially linear flow in a direction substantially parallel to the surface of the wall to cause the particles to impact an additional area of the compromised region to cause the particles to bond to the surface of the additional area. |
| FILED | Thursday, July 25, 2019 |
| APPL NO | 16/521716 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 7/144 (20130101) Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 6/00 (20130101) Original (OR) Class Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 24/04 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11273611 | Aitharaju et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| INVENTOR(S) | Venkateshwar R. Aitharaju (Troy, Michigan); William R. Rodgers (Bloomfield Township, Michigan); Selina X. Zhao (Rochester Hills, Michigan) |
| ABSTRACT | A reinforced preform includes a sheet of reinforced material having opposed first and second edges, with each edge having a respective first connection point located therealong. The preform also includes first and second tethers, with each tether being attached at a respective first end thereof to a respective one of the first connection points and having a respective second end thereof terminating in at least one of: a respective loop tied at the respective second end, a respective knot tied at the respective second end, a respective graspable member to which the respective second end is connected, and an attachment to a respective second connection point located along a perimeter of the sheet. A method and mold for molding a reinforced preform are also disclosed. |
| FILED | Monday, October 07, 2019 |
| APPL NO | 16/594288 |
| ART UNIT | 1748 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Preparation or Pretreatment of the Material to be Shaped; Making Granules or Preforms; Recovery of Plastics or Other Constituents of Waste Material Containing Plastics B29B 11/00 (20130101) B29B 11/14 (20130101) B29B 11/16 (20130101) B29B 13/023 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/467 (20130101) Original (OR) Class B29C 70/541 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/3076 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Technical Subjects Covered by Former US Classification Y10T 428/24 (20150115) Y10T 428/24777 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274042 | Baldwin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Robert Milton Baldwin (Evergreen, Colorado); Mark R. Nimlos (Golden, Colorado); Andrew Nolan Wilson (Denver, Colorado); Maarit Kristiina Iisa (Golden, Colorado) |
| ABSTRACT | Methods are disclosed to make coke, graphite, graphene and other materials from biomass derived bio-oil. |
| FILED | Monday, January 21, 2019 |
| APPL NO | 16/253016 |
| ART UNIT | 1759 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/205 (20170801) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/60 (20130101) C01P 2002/72 (20130101) C01P 2006/80 (20130101) Destructive Distillation of Carbonageous Materials for Production of Gas, Coke, Tar, or Similar Materials C10B 53/02 (20130101) C10B 55/00 (20130101) C10B 57/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274227 | Arumugam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oceanit Laboratories, Inc. (Honolulu, Hawaii) |
| ASSIGNEE(S) | Oceanit Laboratories, Inc. (Honolulu, Hawaii) |
| INVENTOR(S) | Ganesh Kumar Arumugam (Honolulu, Hawaii); Vinod P. Veedu (Houston, Texas); Matthew Nakatsuka (Honolulu, Hawaii) |
| ABSTRACT | A novel omniphobic surface coating is disclosed that provides both high oil-repellency and high-water repellency to the coated surface. The coating may contain perfluoropolyether (PFPE) or a similar fluorinated or perfluorinated polymer, as well as a hardener and a catalyst. One or more surfactants or viscosifiers may also be added. Further, the coating may contain one or more functional additives, including, but not limited to, coloring agents, anti-corrosive agents, anti-fouling agents, water-repellent agents, and/or oil-repellent agents. Methods for formulating the novel omniphobic surface coating are also described. Such methods include preparing a first part of the coating, which may contain, at minimum, a polymer such as PFPE or a similar fluorinated or perfluorinated polymer, and a suitable solvent; preparing a second part of the coating, which is a water-free system that may contain, at minimum, a hardener and a catalyst; and combining the first part and the second part together. |
| FILED | Tuesday, August 06, 2019 |
| APPL NO | 16/533754 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 5/083 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/007 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/3445 (20130101) C08K 5/5435 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 7/63 (20180101) C09D 7/65 (20180101) C09D 171/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274628 | Anders et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Caterpillar Inc. (Peoria, Illinois); UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | Caterpillar Inc. (Peoria, Illinois) |
| INVENTOR(S) | Jonathan William Anders (Peoria, Illinois); Naga Krishna Chaitanya Kavuri (Peoria, Illinois); Bobby John (Peoria, Illinois); Hyderuddin Mohammad (Peoria, Illinois); Chao Xu (Westmont, Illinois); Prithwish Kundu (Pimpri, India) |
| ABSTRACT | An internal combustion engine system includes an engine housing having a combustion cylinder, and a piston movable within the combustion cylinder to increase a pressure therein to an autoignition threshold for injected fuel. The piston includes a piston crown having a combustion face forming a combustion bowl, and varied in profile to form jet-jet interaction limiters at locations offset from fuel spray jet paths from a fuel injector. The jet-jet interaction limiters include a bowl component and a step component protruding, respectively, within the combustion bowl and a step located transitioning between the combustion bowl and a circumferential rim of the piston. Limiting jet-jet interaction limits soot production in exhaust produced by the engine. |
| FILED | Tuesday, June 02, 2020 |
| APPL NO | 16/889958 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion Piston Engines; Combustion Engines in General F02B 23/0678 (20130101) F02B 23/0693 (20130101) Cylinders, Pistons or Casings, for Combustion Engines; Arrangements of Sealings in Combustion Engines F02F 3/20 (20130101) F02F 3/28 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274825 | Lisowski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Darius D. Lisowski (Chicago, Illinois); Dennis J. Kilsdonk (Joliet, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Darius D. Lisowski (Chicago, Illinois); Dennis J. Kilsdonk (Joliet, Illinois) |
| ABSTRACT | The invention provides a device for removing heat from a building, the device having: a first tubular member defining a first cavity; a second tubular member defining a second cavity, whereby said second tubular member resides within the first cavity and is coaxial to the first tubular member; and a double conic body coaxially residing in the first cavity and coaxially positioned with the second tubular member. Also provided is a method for removing heat from a building, the method having the steps of: directing heat-containing exhaust emanating from a flue, defining a first diameter, to a passageway received by the flue, whereby the passageway defines a longitudinal axis and a periphery circumscribing the axis; forming the directed exhaust into a slipstream, wherein the slipstream generally travels along the longitudinal axis; and routing precipitation entering the passageway to the periphery. |
| FILED | Wednesday, July 13, 2016 |
| APPL NO | 15/209267 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Removal or Treatment of Combustion Products or Combustion Residues; Flues F23J 13/06 (20130101) F23J 13/025 (20130101) Original (OR) Class F23J 2213/50 (20130101) Supplying Air or Non-combustible Liquids or Gases to Combustion Apparatus in General; Valves or Dampers Specially Adapted for Controlling Air Supply or Draught in Combustion Apparatus; Inducing Draught in Combustion Apparatus; Tops for Chimneys or Ventilating Shafts; Terminals for Flues F23L 17/02 (20130101) Casings, Linings, Walls or Doors Specially Adapted for Combustion Chambers, e.g Firebridges; Devices for Deflecting Air, Flames or Combustion Products in Combustion Chambers; Safety Arrangements Specially Adapted for Combustion Apparatus; Details of Combustion Chambers, Not Otherwise Provided for F23M 9/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275613 | Basu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Arkaprava Basu (Bangalore, India); Joseph Lee Greathouse (Austin, Texas) |
| ABSTRACT | Systems, apparatuses, and methods for enforcing processor quality of service guarantees when servicing system service requests (SSRs) are disclosed. A system includes a first processor executing an operating system and a second processor executing an application which generates SSRs for the first processor to service. The first processor monitors the number of cycles spent servicing SSRs over a previous time interval, and if this number of cycles is above a threshold, the first processor starts delaying the servicing of subsequent SSRs. In one implementation, if the previous delay was non-zero, the first processor increases the delay used in the servicing of subsequent SSRs. If the number of cycles is less than or equal to the threshold, then the first processor services SSRs without delay. As the delay is increased, the second processor begins to stall and its SSR generation rate falls, reducing the load on the first processor. |
| FILED | Monday, April 16, 2018 |
| APPL NO | 15/954382 |
| ART UNIT | 2196 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/466 (20130101) G06F 9/4887 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11276508 | Carney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Kevin P. Carney (Idaho Falls, Idaho); Martha R. Finck (Ashton, Idaho); Jared J. Horkley (Blackfoot, Idaho); Mathew T. Kinlaw (Idaho Falls, Idaho); Jana K. Pfeiffer (Idaho Falls, Idaho); Erin M. May (Idaho Falls, Idaho); Mathew S. Snow (Idaho Falls, Idaho); Nicholas R. Mann (Idaho Falls, Idaho); Christopher Andrew McGrath (Blackfoot, Idaho) |
| ABSTRACT | Surrogate materials are in the form of solid particles that include surrogate isotopes, namely, short-lived isotopes selected and formed to serve as surrogates for the radioactive materials of a nuclear fallout without including isotopes that are, or that decay to, biologically or environmentally deleterious and persistent isotopes. The surrogate material may be formed using high-purity reactant material and irradiation and separation techniques that enable tailoring of the isotopes and ratios thereof included in the surrogate material, and the surrogate material may be dispersed, e.g., in a training environment, in solid form. |
| FILED | Thursday, December 20, 2018 |
| APPL NO | 16/228465 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Nuclear Reactors G21C 9/02 (20130101) Nuclear Power Plant G21D 3/002 (20190101) G21D 3/04 (20130101) Conversion of Chemical Elements; Radioactive Sources G21G 1/02 (20130101) G21G 1/06 (20130101) Original (OR) Class G21G 1/12 (20130101) G21G 4/00 (20130101) G21G 4/04 (20130101) G21G 2001/0036 (20130101) G21G 2001/0094 (20130101) Obtaining Energy From Radioactive Sources; Applications of Radiation From Radioactive Sources, Not Otherwise Provided For; Utilising Cosmic Radiation G21H 5/00 (20130101) G21H 5/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11276779 | Baliga |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Bantval Jayant Baliga (Raleigh, North Carolina) |
| ABSTRACT | A vertical insulated-gate field effect transistor includes a semiconductor substrate and a gate electrode on a first surface thereof. This gate electrode has a plurality of eight (or more) sided openings extending therethrough. Each of these openings has eight (or more) sidewalls, including a first plurality of sidewalls that are flat relative to a center of the opening and second plurality of sidewalls that are either flat or concave relative to the center of the opening. A source electrode is also provided, which extends into the openings. This source electrode may ohmically contact a source region within the semiconductor substrate. If the field effect transistor is a JBSFET, the source electrode may also form a Schottky rectifying junction with a drift region within the semiconductor substrate. |
| FILED | Tuesday, September 08, 2020 |
| APPL NO | 17/014368 |
| ART UNIT | 2822 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/812 (20130101) H01L 29/0891 (20130101) H01L 29/1608 (20130101) H01L 29/6656 (20130101) H01L 29/6659 (20130101) H01L 29/7811 (20130101) H01L 29/7823 (20130101) H01L 29/7827 (20130101) H01L 29/7836 (20130101) Original (OR) Class H01L 29/42376 (20130101) H01L 29/66666 (20130101) H01L 2924/13063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11276796 | Antunez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Priscilla D. Antunez (Lisle, Illinois); Arthur W. Ellis (Pleasantville, New York); Richard A. Haight (Mahopac, New York); James B. Hannon (Lake Lincolndale, New York); Satoshi Oida (Yorktown Heights, New York) |
| ABSTRACT | Photovoltaic structures having multiple absorber layers separated by a diffusion barrier are provided. In one aspect, a method of forming an absorber on a substrate includes: depositing a first layer of light absorbing material on the substrate; depositing a diffusion barrier; depositing a second layer of light absorbing material on the diffusion barrier, wherein the first layer of light absorbing material has a different band gap from the second layer of light absorbing material; and annealing the absorber, wherein the diffusion barrier prevents diffusion of elements between the first layer of light absorbing material and the second layer of light absorbing material during the annealing. A solar cell and method for formation thereof are also provided. |
| FILED | Tuesday, June 11, 2019 |
| APPL NO | 16/438205 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) H01L 31/0326 (20130101) H01L 31/0352 (20130101) H01L 31/0725 (20130101) Original (OR) Class H01L 31/1864 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11276877 | Yadav et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (New York City, New York) |
| INVENTOR(S) | Gautam G. Yadav (New York, New York); Michael Nyce (New York, New York); Jinchao Huang (New York, New York); Alexander Couzis (New York, New York); Sanjoy Banerjee (New York, New York) |
| ABSTRACT | A battery comprises a housing, an electrolyte disposed in the housing, an anode disposed in the housing, a stabilized cathode disposed in the housing and comprising a cathode material. The cathode material comprises a composition selected from birnessite or layered-polymorph of manganese dioxide (δ-MnO2), the composition being stabilized by bismuth and copper ions, a conductive carbon, and a binder. The anode can be at least 50% (m/m) lithium, magnesium, aluminum, or zinc. |
| FILED | Friday, May 04, 2018 |
| APPL NO | 16/493966 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/0471 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/623 (20130101) H01M 4/625 (20130101) H01M 4/661 (20130101) H01M 4/1391 (20130101) H01M 10/0525 (20130101) Original (OR) Class H01M 2004/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11276884 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Zhengcheng Zhang (Naperville, Illinois); Chi Cheung Su (Westmont, Illinois) |
| ABSTRACT | Described herein are fluoro-substituted ethers of Formula (I): wherein R1 is a fluoro-substituted C2-C6 alkyl group; R2 is a C2-C6 alkyl group or a fluoro-substituted C2-C6 alkyl group; each R3 independently is H, F, methyl, or fluoro-substituted methyl; and n is 0, 1, 2, 3, or 4. The fluoro-substituted ether compounds are useful as solvents for lithium containing electrolytes in lithium batteries, particularly lithium-sulfur batteries. |
| FILED | Thursday, April 11, 2019 |
| APPL NO | 16/381585 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/382 (20130101) H01M 4/623 (20130101) H01M 4/625 (20130101) H01M 10/052 (20130101) H01M 10/0567 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) Original (OR) Class H01M 2300/0034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11277944 | Chainer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Timothy J. Chainer (Putnam Valley, New York); Pritish R. Parida (Fishkill, New York); Mark D. Schultz (Ossining, New York) |
| ABSTRACT | A method for controlling a cooling system based on a heat dissipation of an electronic module and an ambient air temperature includes determining a combination of individual controls on components of the cooling system that achieve a specific amount of cooling based on a cooling power relationship for the plurality of components, the heat dissipation of the electronic module and the ambient air temperature, and applying the individual controls to the plurality of components. |
| FILED | Sunday, April 05, 2020 |
| APPL NO | 16/840402 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20836 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11272878 | Reed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | David A. Reed (Baltimore, Maryland); George C. Emmett (Wilmington, Delaware) |
| ABSTRACT | In an example, a method of detecting cyanide exposure of an individual comprises measuring a thiocyanate level of the individual, and comparing the measured thiocyanate level to a preset thiocyanate threshold to determine whether the measured thiocyanate level is above the preset thiocyanate threshold indicating a level of acute cyanide poisoning for which medical treatment is recommended to treat health effects of the exposure. |
| FILED | Friday, April 30, 2021 |
| APPL NO | 17/246283 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4845 (20130101) Original (OR) Class A61B 5/14551 (20130101) A61B 10/0051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11277265 | Boyd et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Daniel A. Boyd (Arlington, Virginia); Kelli L. Biegger (McLean, Virginia); Chang Ellison (Arlington, Virginia); Brandon P. Gutierrez (Burke, Virginia); Jason Lim (Alexandria, Virginia); William Washington (North Potomac, Maryland) |
| ABSTRACT | An online host method to verify hosted information associated with a user includes establishing, by the online host serving as a relying party system (RPS), a secure connection between the RPS and a user mobile-identification-credential device (UMD). The RPS sends a mobile identification credential (MIC) user information request to the UMD, via the secure connection, seeking release of MIC user information (official information). The RPS obtains from authorizing party system (APS) verification of the MIC user information received in response to the MIC user information request. The RPS stores the MIC user information as hosted information pertaining to the user. The RPS designates the hosted information as base truth information representing the user. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/180421 |
| ART UNIT | 2493 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0825 (20130101) H04L 9/3213 (20130101) Original (OR) Class H04L 9/3247 (20130101) H04L 63/0823 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11277557 | Vemury |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Arun Vemury (North Bethesda, Maryland) |
| ABSTRACT | Systems and methods are disclosed and an example system includes a digital image receiver for receiving a digital image, and an automatic obscuration processor coupled to the image receiver, and configured to determine whether the digital image includes a region that classifies as an image of a category of object and, upon a positive determination, to obscure the region and output a corresponding obscured-region digital image. |
| FILED | Friday, March 26, 2021 |
| APPL NO | 17/213851 |
| ART UNIT | 2696 — Selective Visual Display Systems |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 2207/20008 (20130101) G06T 2207/20224 (20130101) Pictorial Communication, e.g Television H04N 5/272 (20130101) H04N 5/2252 (20130101) H04N 5/23219 (20130101) Original (OR) Class H04N 5/23222 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11275012 | Bencic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Timothy J. Bencic (Highland Heights, Ohio); David P. Rohler (Shaker Heights, Ohio); Amy F. Fagan (Fairview Park, Ohio); Steven H. Izen (Shaker Heights, Ohio); Arjun K. Maniyedath (Beachwood, Ohio) |
| ASSIGNEE(S) | PLEXAR ASSOCIATES, INC. (Shaker Heights, Ohio) |
| INVENTOR(S) | Timothy J. Bencic (Highland Heights, Ohio); David P. Rohler (Shaker Heights, Ohio); Amy F. Fagan (Fairview Park, Ohio); Steven H. Izen (Shaker Heights, Ohio); Arjun K. Maniyedath (Beachwood, Ohio) |
| ABSTRACT | A tomography duct for wind tunnels includes a plurality of light sources and sensors displaced around a support structure. The light sources are cycled and sensor measurements are made from sensors opposite the light sources. Tomographic algorithms are used to determine an extinction map from the sensor measurements. The extinction map provides details about particles in a cross-section of the air flow through the tomography duct. |
| FILED | Tuesday, February 02, 2021 |
| APPL NO | 17/165308 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/06 (20130101) Original (OR) Class G01N 33/0009 (20130101) G01N 33/0031 (20130101) G01N 33/0036 (20130101) G01N 2015/0026 (20130101) G01N 2015/0046 (20130101) G01N 2015/0693 (20130101) G01N 2033/1873 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275481 | Clausen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Matthew C. Clausen (Los Angeles, California); Charles Goddard (Los Angeles, California); Garrett K. Johnson (Pasadena, California); Marsette A. Vona, III (Los Angeles, California); Victor X. Luo (Pasadena, California); Jeffrey S. Norris (Saratoga, California); Anthony Valderrama (Pasadena, California); Alexandra E. Samochina (Los Angeles, California) |
| ABSTRACT | A method and system control navigation of a 3D CAD model in an augmented reality space. The 3D CAD model is rendered and appears as if the 3D CAD model is present in a physical space at true scale. A constrained translate or rotation mode is activated. In response to the activating, an axis triad is rendered. For translate, the axis triad is three lines extending from a point in each principal axis direction, and division markers are displayed along the lines at predefined division distances. One of the division markers is selected and the model is moved the predefined division distance of the selected division marker along the first line. For rotation, the axis triad is three perpendicular rings, and upon selecting one of the rings, an input gesture causes the model to rotate around the selected axis in the direction of the input gesture. |
| FILED | Tuesday, May 19, 2020 |
| APPL NO | 16/878210 |
| ART UNIT | 2623 — Selective Visual Display Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 3/013 (20130101) G06F 3/017 (20130101) G06F 3/04815 (20130101) Original (OR) Class G06F 30/10 (20200101) G06F 2111/18 (20200101) Image Data Processing or Generation, in General G06T 19/006 (20130101) G06T 19/20 (20130101) G06T 2200/24 (20130101) G06T 2219/024 (20130101) G06T 2219/2016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11276880 | Smirnova et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | South Dakota Board of Regents (Pierre, South Dakota) |
| ASSIGNEE(S) | South Dakota Board of Regents (Pierre, South Dakota) |
| INVENTOR(S) | Alevtina Smirnova (Rapid City, South Dakota); Matthew Dondelinger (Rapid City, South Dakota); Joel Swanson (Rapid City, South Dakota) |
| ABSTRACT | The present disclosure relates to a manufacturing process of the solid-state glass-ceramic electrolytes, known in the art as antiperovskites. Specifically, the disclosure is focused on manufacturing of the solid-state electrolyte from the corresponding precursors directly on the active electrode surface of an electrochemical device, specifically anode or cathode of the lithium-ion or lithium metal batteries. |
| FILED | Tuesday, October 01, 2019 |
| APPL NO | 16/589429 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/661 (20130101) H01M 10/052 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2004/027 (20130101) H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11273473 | Quigley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts); Nicole Neff (Colorado Springs, Colorado); Jack Rowbottom (Swansea, Massachusetts) |
| ABSTRACT | A control system for controlling extraction of landfill gas from a landfill via a gas extraction system, the gas extraction system comprising well piping for coupling a plurality of wells to a gas output. The control system comprises a controller configured to: obtain a value indicating measured energy content of landfill gas collected at the gas output from the plurality of wells; determine whether the measured energy content is different from a target energy content; and in response to determining that the measured energy content is different from the target energy content: control a plurality of valves disposed in the well piping to change flow rates of landfill gas being extracted from at least some of the plurality of wells at least in part by changing degrees to which the plurality of valves are open. |
| FILED | Monday, June 15, 2020 |
| APPL NO | 16/901430 |
| ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 34/02 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/30 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11275071 | Schwabacher et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UWM Research Foundation, Inc. (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | UWM Research Foundation, Inc. (Milwaukee, Wisconsin) |
| INVENTOR(S) | Alan Schwabacher (Shorewood, Wisconsin); Peter Geissinger (Shorewood, Wisconsin); Trevor Hagemann (Milwaukee, Wisconsin); Sarah Oehm (Milwaukee, Wisconsin); Tyler G. Fenske (Milwaukee, Wisconsin) |
| ABSTRACT | Sensors for detecting and distinguishing metals in a sample comprise phenol group-containing azo dyes, the phenol group having one hydroxy involved in reversible metal ion binding and a second hydroxy alkylated to an optically transparent substrate. The sensors have utility for detecting chromium, calcium, magnesium, copper, mercury, nickel, zinc, cobalt, manganese, cadmium, lead, tin, aluminum, potassium, sodium, or arsenic ions in a sample. |
| FILED | Friday, October 14, 2016 |
| APPL NO | 15/767175 |
| ART UNIT | 1796 — Optics |
| CURRENT CPC | Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 29/0048 (20130101) C09B 29/3621 (20130101) C09B 29/3643 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) G01N 21/643 (20130101) G01N 33/1813 (20130101) Original (OR) Class G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11277419 | Crouch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Amida Technology Solutions, Inc. (Washinton, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alfred Larry Crouch (Cedar Park, Texas); Peter Lawrence Levin (Silver Springs, Maryland); John David Akin (Plano, Texas); Adam Wade Ley (Allen, Texas); Matthew McKinnon Ritonia (Arlington, Virginia); Wesley Layton Ellington (Dallas, Texas); Maria Anne Spasojevic (Palo Alto, California) |
| ABSTRACT | A method and system for analysis of a facility may include providing an emulation host system, generating a pristine circuit model on the emulation host system, inserting a first hardware trojan model, emulating operation of the golden circuit model, and emulating operation of the first hardware trojan model, and determine a set of machine-learning models, detecting the presence of an unknown trojan as a function of the set of machine learning models and using the same to authenticate the integrity of a GPS signal. |
| FILED | Sunday, December 27, 2020 |
| APPL NO | 17/134441 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/23 (20130101) G01S 19/42 (20130101) Electric Digital Data Processing G06F 16/2379 (20190101) Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11273162 | Swiderski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cyprianna Swiderski (Starkville, Mississippi); Courtney Hunter (Jackson, Mississippi) |
| ASSIGNEE(S) | Mississippi State University (Starkville, Mississippi) |
| INVENTOR(S) | Cyprianna Swiderski (Starkville, Mississippi); Courtney Hunter (Jackson, Mississippi) |
| ABSTRACT | An object of the present invention to provide therapeutic compositions and methods for the prevention and/or treatment of airway obstructive disorders that involve bronchial hyper-responsiveness (BHR), asthma, horse asthma, airway remodeling that potentiate BHR, and any other airway obstructive disorders that involve bronchial smooth muscle (BSM) constriction or possibly other airway smooth muscle (ASM) constriction in a subject in need thereof. Compositions and methods for targeting HCN channels in airway smooth muscle to treat and/or prevent asthma and asthma-like conditions are disclosed. The compositions and methods include administering a therapeutically effective amount of HCN channel blocker, preferably ivabradine hydrochloride, to a subject in need thereof. |
| FILED | Monday, April 03, 2017 |
| APPL NO | 16/089795 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) Original (OR) Class A61K 31/55 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/06 (20180101) Peptides C07K 14/705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274329 | Ramasamy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| INVENTOR(S) | Ramaraja P. Ramasamy (Watkinsville, Georgia); Yi Fang (Athens, Georgia) |
| ABSTRACT | Provided herein are plant/plant pathogen volatile compound electrochemical sensors, plant/plant pathogen volatile detection systems, and methods for detecting stress-induced plant volatile compounds and/or a plant-pathogen emitted volatile compounds. |
| FILED | Wednesday, December 11, 2019 |
| APPL NO | 16/710059 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 9/26 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/005 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3277 (20130101) G01N 27/3278 (20130101) G01N 33/025 (20130101) G01N 33/0047 (20130101) G01N 33/0098 (20130101) G01N 33/483 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11274303 | Pajukanta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); UNITED STATES GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia); UNIVERSITY OF EASTERN FINLAND (Kuopio, Finland) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); UNITED STATES GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia); UNIVERSITY OF EASTERN FINLAND (Kuopio, Finland) |
| INVENTOR(S) | Paivi E. Pajukanta (Los Angeles, California); Joseph R. Pisegna (Los Angeles, California); Jihane N. Benhammou (Los Angeles, California); Arthur Ko (Los Angeles, California); Jussi Pihlajamäki (Kuopio, Finland) |
| ABSTRACT | An oligonucleotide that inhibits expression of an OLMALINC nucleic acid molecule, such as a small inhibitory RNA (siRNA) molecule, can be used for inhibiting the expression of OLMALINC in a subject. Methods of assaying for OLMALINC in a tissue sample can be used for detecting a disorder associated with obesity and/or type 2 diabetes in a tissue sample obtained from a subject. A method of ameliorating symptoms associated with obesity and/or type 2 diabetes comprises administering to a subject in need thereof an effective amount of an oligonucleotide of the invention or an antibody or equivalent thereof that specifically binds to and inactivates an OLMALINC nucleic acid molecule. Representative examples of a disorder associated with obesity and/or type 2 diabetes include, but are not limited to, a disorder of appetite, glycemia, body weight, liver steatosis, NASH, NAFLD, or a lipid disorder. |
| FILED | Friday, October 05, 2018 |
| APPL NO | 16/753962 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/20 (20170501) C12N 2310/113 (20130101) C12N 2320/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274305 | Howell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as Represented by The Department of Veterans Affairs (Washington, District of Columbia); TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire); United States Government as Represented by The Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Alexandra L. Howell (Lyme, New Hampshire); Susan K. Eszterhas (Plainfield, New Hampshire) |
| ABSTRACT | Methods and kits for excising HIV-1 DNA in vivo are provided, which employ Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-Associated (cas) proteins. Vectors harboring nucleic acids encoding one or more guide RNA, wherein said guide RNA hybridizes with a target HIV-1 DNA are also provided. |
| FILED | Tuesday, March 25, 2014 |
| APPL NO | 14/782297 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) A61K 38/1709 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/1132 (20130101) Original (OR) Class C12N 2320/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 11274124 | Nicolaou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Kyriacos C. Nicolaou (Houston, Texas); Rohan Diliprao Erande (Houston, Texas); Dionisios Vourloumis (Houston, Texas); Kiran Kumar Pulukuri (Houston, Texas); Stephan Rigol (Houston, Texas) |
| ABSTRACT | In one aspect, the present disclosure provides tubulysin analogs of the formula (I) wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. Additionally, drug conjugates with cell targeting moieties of the compounds are also provided. |
| FILED | Wednesday, November 28, 2018 |
| APPL NO | 16/767999 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/6803 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 229/22 (20130101) Heterocyclic Compounds C07D 319/06 (20130101) Peptides C07K 5/06139 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274329 | Ramasamy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| INVENTOR(S) | Ramaraja P. Ramasamy (Watkinsville, Georgia); Yi Fang (Athens, Georgia) |
| ABSTRACT | Provided herein are plant/plant pathogen volatile compound electrochemical sensors, plant/plant pathogen volatile detection systems, and methods for detecting stress-induced plant volatile compounds and/or a plant-pathogen emitted volatile compounds. |
| FILED | Wednesday, December 11, 2019 |
| APPL NO | 16/710059 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 9/26 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/005 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3277 (20130101) G01N 27/3278 (20130101) G01N 33/025 (20130101) G01N 33/0047 (20130101) G01N 33/0098 (20130101) G01N 33/483 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 11274124 | Nicolaou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Kyriacos C. Nicolaou (Houston, Texas); Rohan Diliprao Erande (Houston, Texas); Dionisios Vourloumis (Houston, Texas); Kiran Kumar Pulukuri (Houston, Texas); Stephan Rigol (Houston, Texas) |
| ABSTRACT | In one aspect, the present disclosure provides tubulysin analogs of the formula (I) wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. Additionally, drug conjugates with cell targeting moieties of the compounds are also provided. |
| FILED | Wednesday, November 28, 2018 |
| APPL NO | 16/767999 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/6803 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 229/22 (20130101) Heterocyclic Compounds C07D 319/06 (20130101) Peptides C07K 5/06139 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11274251 | Crowley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raphael Crowley (Ponte Vedra Beach, Florida); Matthew Davies (Saint Johns, Florida); Nick Hudyma (Boise, Idaho); Joshua Sasser (Jacksonville, Florida) |
| ASSIGNEE(S) | University of North Florida Board of Trustees (Jacksonville, Florida) |
| INVENTOR(S) | Raphael Crowley (Ponte Vedra Beach, Florida); Matthew Davies (Saint Johns, Florida); Nick Hudyma (Boise, Idaho); Joshua Sasser (Jacksonville, Florida) |
| ABSTRACT | Methods for increasing soil stabilization utilizing an anionic surfactant and a solution. Varying amounts of the anionic surfactant sodium dodecyl sulfate (“SDS”) is added to soils along with a solution of calcium chloride. A mixing procedure is then used to mix the SDS-soil matrix with the calcium chloride solution. The micelles surround the soil particles, creating a matrix, and then the calcium ions of the calcium chloride solution bonds the micelle complex together. The resulting calcium dodecyl sulfate (“CDS”) complex is very hard, relatively insoluble, and very strong. This process can be reversed by exposing the CDS complex to seawater. The sodium ions of the seawater exchange with the calcium ions of the CDS complex reforming the SDS surfactant. |
| FILED | Friday, July 10, 2020 |
| APPL NO | 16/946919 |
| ART UNIT | 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 17/48 (20130101) Original (OR) Class C09K 2101/00 (20130101) Foundations; Excavations; Embankments; Underground or Underwater Structures E02D 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 11276728 | Heron et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); Cornell University (Ithaca, New York) |
| INVENTOR(S) | John Thomas Heron (Saline, Michigan); Peter Benjamin Meisenheimer (Ann Arbor, Michigan); Darrell G. Schlom (Ithaca, New York); Rachel Steinhardt (Brooktondale, New York) |
| ABSTRACT | A heterostructure includes a substrate exhibiting a piezoelectric effect, and a magnetostrictive film supported by the substrate. The magnetostrictive film includes an iron-gallium alloy. The iron-gallium alloy has a gallium composition greater than 20%. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 16/784351 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/20 (20130101) Original (OR) Class H01L 41/09 (20130101) H01L 41/20 (20130101) H01L 41/47 (20130101) H01L 41/125 (20130101) H01L 41/1875 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 11274908 | Vabnick |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Federal Bureau of Investigation (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Federal Bureau of Investigation, Department of Justice (Washington, District of Columbia) |
| INVENTOR(S) | Ian B. Vabnick (Quantico, Virginia) |
| ABSTRACT | Provided herein are penetrator projectiles for use with explosive ordnance disposal disrupters, and related methods of making and using. The penetrator projectile has a tip, neck, shaft and base, wherein the geometry and composition of the different elements are selected to ensure the projectile is ballistically stable after firing to provide improved free-flight characteristics and corresponding explosive ordnance disruption. |
| FILED | Tuesday, December 04, 2018 |
| APPL NO | 16/209643 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/08 (20130101) Original (OR) Class Blasting F42D 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 11274251 | Crowley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raphael Crowley (Ponte Vedra Beach, Florida); Matthew Davies (Saint Johns, Florida); Nick Hudyma (Boise, Idaho); Joshua Sasser (Jacksonville, Florida) |
| ASSIGNEE(S) | University of North Florida Board of Trustees (Jacksonville, Florida) |
| INVENTOR(S) | Raphael Crowley (Ponte Vedra Beach, Florida); Matthew Davies (Saint Johns, Florida); Nick Hudyma (Boise, Idaho); Joshua Sasser (Jacksonville, Florida) |
| ABSTRACT | Methods for increasing soil stabilization utilizing an anionic surfactant and a solution. Varying amounts of the anionic surfactant sodium dodecyl sulfate (“SDS”) is added to soils along with a solution of calcium chloride. A mixing procedure is then used to mix the SDS-soil matrix with the calcium chloride solution. The micelles surround the soil particles, creating a matrix, and then the calcium ions of the calcium chloride solution bonds the micelle complex together. The resulting calcium dodecyl sulfate (“CDS”) complex is very hard, relatively insoluble, and very strong. This process can be reversed by exposing the CDS complex to seawater. The sodium ions of the seawater exchange with the calcium ions of the CDS complex reforming the SDS surfactant. |
| FILED | Friday, July 10, 2020 |
| APPL NO | 16/946919 |
| ART UNIT | 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 17/48 (20130101) Original (OR) Class C09K 2101/00 (20130101) Foundations; Excavations; Embankments; Underground or Underwater Structures E02D 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 11275712 | Tschirhart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northrop Grumman Systems Corporation (Falls Church, Virginia) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Paul Kenton Tschirhart (Odenton, Maryland); Brian Konigsburg (Pasadena, Maryland) |
| ABSTRACT | In an embodiment, a method for processing data in a single instruction multiple data (SIMD) computer architecture is provided. A processing element (PE) may determine based on a masking instruction, a predication state indicative of one of a conditional predication mode and an absolute predication mode. The PE may receive a predicated instruction and, based on a value of a head bit of the bits of a predication mask and on the value indicative of the predication state whether to commit a computation corresponding to execution of the predicated instruction. In another embodiment, a SIMD controller stores loops and sections of a program as a separate instruction stream record for generating the memory address of the next instruction. For data streams, the SIMD controller records information for each data memory access that references the same register files that are used by the instruction streams. |
| FILED | Thursday, August 20, 2020 |
| APPL NO | 16/998186 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3887 (20130101) G06F 9/30018 (20130101) G06F 9/30101 (20130101) G06F 9/30185 (20130101) G06F 15/8007 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11274770 | Marshall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Travis H. Marshall (West Hartford, Connecticut); Adam Mocarski (New Britain, Connecticut) |
| ABSTRACT | An assembly is provided for a piece of rotational equipment. This assembly includes a first structure, a second structure and a fluid transfer assembly. The first structure is configured with an aperture. The second structure is configured as or otherwise includes a port. The fluid transfer assembly includes a fluid conduit and a slider element. The fluid conduit is configured as a monolithic tubular body that includes a first conduit end, a second conduit end, a first coupling and a second coupling. The fluid conduit extends axially along a centerline from the first conduit end, through the aperture and into the port to the second conduit end. The first coupling is mated with the first structure through the slider element. The second coupling is mated with the second structure through a cone seal interface. |
| FILED | Thursday, April 18, 2019 |
| APPL NO | 16/388316 |
| ART UNIT | 3631 — Static Structures, Supports and Furniture |
| CURRENT CPC | Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 3/01 (20130101) Original (OR) Class F16L 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, March 15, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/details-patents-20220315.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page