FedInvent™ Patents
Patent Details for Tuesday, March 22, 2022
This page was updated on Wednesday, March 23, 2022 at 05:38 PM GMT
Department of Defense (DOD)
US 11278235 | Herr et al. |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Hugh M. Herr (Somerville, Massachusetts); Matthew Eli Carney (Somerville, Massachusetts); Emily Ann Rogers (Somerville, Massachusetts); Lucy Wei Du (Cambridge, Massachusetts) |
ABSTRACT | A prosthetic device includes a frame defining an output axis, a cantilever beam spring attached to the frame, a moment arm attached to the spring, and a rigid output arm coupled to the frame and rotatable about the output axis. A connector assembly is configured to apply a moment to the cantilever beam spring via the moment arm while applying a torque about the output axis via the output arm. An ankle-foot device includes foot and ankle members connected for two-degree of freedom movement relative to one another, allowing for rotation about an ankle axis and rotation about a subtalar axis. Two linear actuators, each coupled to corresponding series elastic element, link the foot and ankle members. Driving the actuators in the same direction causes rotation about the ankle axis and driving the actuators in opposing directions causes rotation about the subtalar axis. A processor receives sensory information from a sensor and drives the actuators to control an equilibrium position of the series elastic elements. A rotary actuator for a prosthetic device includes a housing frame, a motor mounted within the housing frame, and a cycloidal drive coupled to the motor within the housing frame. A torsion shaft can extend through the actuator to an output and provide a series elastic element. |
FILED | Wednesday, October 23, 2019 |
APPL NO | 16/661483 |
ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/389 (20210101) Original (OR) Class A61B 5/688 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/64 (20130101) A61F 2/72 (20130101) A61F 2/741 (20210801) A61F 2/6607 (20130101) A61F 2002/6664 (20130101) Electric Digital Data Processing G06F 3/015 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278367 | Diaz et al. |
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APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Indian Head, Maryland) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Angel Diaz (Indian Head, Maryland); David Rivera-Marchand (Alexandria, Virginia); Lonnie Frericks (King George, Virginia); Andrew Wojtkowski (Springfield, Virginia); Anthony Kummerer (LaPlata, Maryland) |
ABSTRACT | A portable and collapsible apparatus for holding fiducial markers has a first section that includes a frame, an opposite second side, a first panel attached to the first frame and fiducial markers attached to the first panel. The apparatus includes a second section pivotably attached to the first section and a second frame, an opposite second side, a second panel member attached to the second frame and fiducial markers attached to the second panel. The apparatus is configurable to a closed state by pivoting the first section and second section toward each other where the rear sides of the first frame and second frame contact each other. The apparatus is configurable to an opened state by pivoting the first section and second section away from each other. In the opened state, the first section and second section are vertically oriented with respect to a surface. |
FILED | Thursday, October 31, 2019 |
APPL NO | 16/602554 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 50/22 (20160201) Original (OR) Class A61B 90/39 (20160201) A61B 2090/3966 (20160201) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/04 (20130101) G01N 2223/301 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278442 | Tomblin et al. |
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APPLICANT(S) | Wichita State University (Wichita, Kansas); Commercial Chemistries, LLC (Cottonwood Heights, Utah) |
ASSIGNEE(S) | Wichita State University (Wichita, Kansas); Commercial Chemistries, LLC (Cottonwood Heights, Utah) |
INVENTOR(S) | John S. Tomblin (Wichita, Kansas); Thomas Aldag (Wichita, Kansas); William T. McCarvill (Cottonwood Heights, Utah); Kimberly M. Reuter (Wichita, Kansas); Joel D. White (Wichita, Kansas); Andrea C. Meyer (Bel Aire, Kansas) |
ABSTRACT | A fiber-reinforced composite article useful in supporting or immobilizing an injured body part is disclosed. The composite is a multi-layer, flexible precursor including fiber reinforcement plies, which can be rapidly cured into a rigid body using a thermosetting resin. Methods of making and using the same are also disclosed, along with kits containing such composite articles. |
FILED | Monday, May 13, 2019 |
APPL NO | 16/410200 |
ART UNIT | 3786 — Body Treatment, Kinestherapy, and Exercising |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/01 (20130101) A61F 5/0585 (20130101) A61F 5/05825 (20130101) Original (OR) Class A61F 5/05841 (20130101) A61F 13/04 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/08 (20130101) A61L 15/12 (20130101) A61L 15/12 (20130101) A61L 15/12 (20130101) A61L 15/14 (20130101) A61L 15/125 (20130101) A61L 15/125 (20130101) Compositions of Macromolecular Compounds C08L 33/10 (20130101) C08L 33/10 (20130101) C08L 35/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278469 | Tracey et al. |
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APPLICANT(S) | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (Manhasset, New York) |
ASSIGNEE(S) | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (Manhasset, New York) |
INVENTOR(S) | Kevin J. Tracey (Old Greenwich, Connecticut); Sangeeta S. Chavan (Syosset, New York) |
ABSTRACT | Methods are disclosed for treating a subject having a disease or disorder comprising providing the subject with an acoustic energy stimulus derived from a disease-specific, condition-specific, endogenous mediator-specific or pharmacologic agent-specific neurogram in an amount and manner effective to treat the disease or disorder. |
FILED | Tuesday, August 15, 2017 |
APPL NO | 15/677062 |
ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/24 (20210101) A61B 5/14532 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 23/00 (20130101) Original (OR) Class A61H 23/0236 (20130101) A61H 2230/08 (20130101) A61H 2230/085 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278613 | Hashey et al. |
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APPLICANT(S) | GLAXOSMITHKLINE BIOLOGICALS SA (Rixensart, Belgium) |
ASSIGNEE(S) | GLAXOSMITHKLINE BIOLOGICALS SA (Rixensart, Belgium) |
INVENTOR(S) | Kathryn Hashey (Washington, District of Columbia); Padma Malyala (Cambridge, Massachusetts); Marcelo Samsa (Rockville, Maryland); Olga Slack (Cambridge, Massachusetts); Dong Yu (Rockville, Maryland); Alan Stokes (Rockville, Maryland); Rashmi Jalah (Rockville, Maryland) |
ABSTRACT | Nucleic acid based vaccine constructs encoding Lyssaviral antigens are useful in preventing and treating diseases. Self-amplifying RNA molecules encoding Lyssaviral antigens provide potent and long-lasting immunity. |
FILED | Monday, July 16, 2018 |
APPL NO | 16/630951 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 39/205 (20130101) Original (OR) Class A61K 2039/53 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278621 | Gainer et al. |
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APPLICANT(S) | Diffusion Pharmaceuticals LLC (Charlottesville, Virginia) |
ASSIGNEE(S) | DIFFUSION PHARMACEUTICALS LLC (Charlottesville, Virginia) |
INVENTOR(S) | John L. Gainer (Charlottesville, Virginia); Marc Lanz (Reitnau, Switzerland) |
ABSTRACT | The invention relates to trans carotenoid compounds and salts thereof as well as compositions thereof, methods for making them, and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans. |
FILED | Tuesday, March 20, 2018 |
APPL NO | 15/926709 |
ART UNIT | 1622 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 31/11 (20130101) A61K 31/202 (20130101) A61K 41/0038 (20130101) Original (OR) Class A61K 45/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Acyclic or Carbocyclic Compounds C07C 57/03 (20130101) C07C 57/13 (20130101) C07C 69/602 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278722 | Howard et al. |
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APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
INVENTOR(S) | Michael D. Howard (Westlake Village, California); Praveen K. Pilly (West Hills, California); Michael J. Daily (Thousand Oaks, California) |
ABSTRACT | Described is a system for cueing a specific memory in a waking state. The system sends an initiation signal to a memory recall controller to select a stored stimulation pattern previously associated with a specific memory of an event. The system signals to a memory recall controller to initiate delivery of the selected stimulation pattern to a brain in a waking state for a duration of the event via a brain stimulation system. Following completion of the event, the system signals for the memory recall controller to stop the brain stimulation system from delivering the selected stimulation pattern. |
FILED | Wednesday, April 03, 2019 |
APPL NO | 16/374433 |
ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0456 (20130101) A61N 1/36025 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279062 | Das et al. |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
INVENTOR(S) | Suman Das (Atlanta, Georgia); Dajun Yuan (San Diego, California); Anirudh Rudraraju (Hillsboro, Oregon); Paul Cilino (Atlanta, Georgia) |
ABSTRACT | A system including: a container for holding a photosensitive medium adapted to change states upon exposure to a light source; an optical imaging system, configured to move above the container holding the photosensitive medium, and having the light source; and a control system configured to: slice a digital model of a three-dimensional object into a slice having a cross section; generate a build cross section by filling a two-dimensional image with one or more copies of the cross section; add to the build cross section a conformal lattice to fill space in the build cross section around the one or more copies of the cross section; and control movement of the optical imaging system above the container to cure a portion of the photosensitive medium corresponding to the build cross section to produce a layer of a three-dimensional object. |
FILED | Monday, August 27, 2018 |
APPL NO | 16/113338 |
ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Foundry Moulding B22C 9/02 (20130101) B22C 9/10 (20130101) B22C 9/24 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 35/0805 (20130101) Original (OR) Class B29C 64/40 (20170801) B29C 64/129 (20170801) B29C 64/135 (20170801) B29C 2035/0827 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/70291 (20130101) G03F 7/70416 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/25 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279483 | Provenza |
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APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
INVENTOR(S) | Jerry Provenza (Niceville, Florida) |
ABSTRACT | A modular weapon carriage and deployment (MWCD) system includes a strongback structure mountable to an aircraft. Left and right guide struts have respective upper ends attached to the strongback structure in spaced lateral positions. Each guide strut extends downward in a parallel arrangement. Each guide strut comprising a vertically-extending first engaging surface. Left and right suspension modules are engageable to opposite lateral sides of a first airborne store. Each suspension module includes a vertical channel that receives the engaging surface of the corresponding one of the left and right guide struts for relative vertical translation. A locking mechanism controllably locks to first engaging surface of the corresponding one of the left and right guide struts. |
FILED | Wednesday, November 14, 2018 |
APPL NO | 16/190711 |
ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 1/00 (20130101) Original (OR) Class B64D 7/00 (20130101) Apparatus for Launching Projectiles or Missiles From Barrels, e.g Cannons; Launchers for Rockets or Torpedoes; Harpoon Guns F41F 3/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279590 | Bultman et al. |
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APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | David Alan Bultman (San Diego, California); Rudy Padilla (San Diego, California) |
ABSTRACT | A system and method for non-contact measurement of remaining spooled material. The system comprises at least one optical signal source configured to illuminate spooled material with an optical beam having an optical beam width that illuminates the material remaining in the spool. The optical beam width and spacing are such that spooled material is illuminated by each optical signal source. The system includes drive circuitry configured to drive the at least one optical signal source using pulses. The system further includes at least one optical signal receiver configured to receive light reflected from each of said light pulses. The system still further includes a processor configured to: establish a number and drive strength of the pulses; and cause measurements to be performed of the remaining spooled material. |
FILED | Monday, January 27, 2020 |
APPL NO | 16/773753 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Handling Thin or Filamentary Material, e.g Sheets, Webs, Cables B65H 61/00 (20130101) Original (OR) Class B65H 2511/112 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/00 (20130101) G01B 11/026 (20130101) G01B 11/043 (20130101) G01B 11/105 (20130101) Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 17/00 (20130101) Image Data Processing or Generation, in General G06T 7/62 (20170101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279613 | Starman et al. |
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APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
ASSIGNEE(S) | |
INVENTOR(S) | LaVern A. Starman (Dayton, Ohio); John P K Walton (Troy, Ohio); Harris J Hall (Yellow Springs, Ohio) |
ABSTRACT | An actuator element of a MEMS device is provided, which is fabricated using surface micromachining on a substrate. An insulating layer having a first portion contacts the substrate while a second portion is separated from the substrate by a gap. A metallic layer contacts the insulating layer having a first portion contacting the first portion of the insulating layer and a second portion contacting the second portion of the insulating layer. The second portion of the metallic layer is prestressed. Alternately, the actuator element includes a first insulating layer separated from the substrate by a gap. A metallic layer has a first portion contacting the substrate and a second portion contacting the insulating layer. A second insulating layer contacts a portion of the second portion of the metallic layer opposite the first insulating layer, where the second insulating layer is prestressed. |
FILED | Wednesday, August 01, 2018 |
APPL NO | 16/052018 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0043 (20130101) Original (OR) Class B81B 2201/032 (20130101) B81B 2201/042 (20130101) B81B 2203/053 (20130101) B81B 2203/058 (20130101) Optical Elements, Systems, or Apparatus G02B 26/0833 (20130101) G02B 26/0841 (20130101) G02B 26/0866 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279642 | Arnett et al. |
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APPLICANT(S) | United States of America as Represented by The Secretary of the Army (Alexandria, Virginia) |
ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
INVENTOR(S) | Clint M Arnett (Mahomet, Illinois); Martin A Page (Urbana, Illinois); Donald M Cropek (Champaign, Illinois); Ashley N Boyd (Champaign, Illinois); Justin Lange (Mahomet, Illinois) |
ABSTRACT | A recombinant Moringa oleifera coagulant protein (MO) produced and secreted by Bacillus has coagulation/flocculation activity. The MO protein and the Bacillus host cells expressing the MO protein can be used in compositions and methods for treating contaminated water, such as drinking water or waste water. The MO protein can coagulate or flocculate suspended solid impurities in the water, which can then be removed. |
FILED | Wednesday, September 25, 2019 |
APPL NO | 16/582959 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 3/34 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/75 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279734 | Pentelute et al. |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Bradley L. Pentelute (Cambridge, Massachusetts); Faycal Touti (Cambridge, Massachusetts) |
ABSTRACT | The present invention provides novel peptides (e.g., peptides, macrocyclic peptides, mini-proteins) that modulate protein-protein interactions or salts thereof, and methods of making and using the inventive peptides. In some embodiments, the peptides are high affinity inhibitors (e.g., KD of at most 100 nM, at most 10 nM, at most 1 nM) of a protein-protein interaction. In certain embodiments, these peptides interfere with p53-MDM2 binding interactions (e.g., by binding to MDM2 (GenBank® Gene ID: 4193)). In some embodiments, the peptides interfere with the dimerization of the C-terminal domain of the human immunodeficiency virus (HIV) capsid protein (C-CA), comprising residues 146-231 of the HIV capsid protein (e.g., by binding to the C-terminal domain of the HIV capsid protein (C-CA), thereby inhibiting the dimeric interface of HIV capsid protein, thereby inhibiting viral assembly). These inventive peptides were rapidly generated and identified using novel methods described herein comprising combinatorial peptide synthesis and/or solution affinity selection. |
FILED | Friday, November 30, 2018 |
APPL NO | 16/206944 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/12 (20180101) A61P 35/00 (20180101) Peptides C07K 1/22 (20130101) C07K 7/08 (20130101) C07K 7/64 (20130101) Original (OR) Class C07K 14/00 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6845 (20130101) G01N 33/6848 (20130101) G01N 2500/20 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279763 | Chen |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Lu Chen (Oakland, California) |
ABSTRACT | In certain embodiments, the present invention provides methods of suppressing valvulogenesis (VG) in a lymphatic vessel in an inflamed or transplanted tissue or organ in a mammal in need thereof comprising administering an effective amount of an anti-integrin alpha 9 (Itga-9) therapeutic agent to the mammal, and optionally by administering anti-VEGFR-3 agent. |
FILED | Thursday, October 26, 2017 |
APPL NO | 16/344741 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0048 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) Peptides C07K 16/2839 (20130101) Original (OR) Class C07K 2317/54 (20130101) C07K 2317/56 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279765 | Fukumura et al. |
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FUNDED BY |
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APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Dai Fukumura (Newton, Massachusetts); Keehoon Jung (Boston, Massachusetts); Rakesh K. Jain (Wellesley, Massachusetts) |
ABSTRACT | Agents that inhibit CX3CL1 in endothelial cells to reduce or inhibit immunosuppression mechanisms that are co-opted by cancer cells to evade host immune system, and that reduce immunosuppression in context of therapies that target VEGF-dependent signaling, and methods of use thereof. |
FILED | Monday, July 09, 2018 |
APPL NO | 16/628941 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/5123 (20130101) A61K 31/713 (20130101) A61K 47/62 (20170801) A61K 47/6935 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/24 (20130101) C07K 16/2866 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1136 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279923 | Funkner et al. |
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APPLICANT(S) | CureVac AG (Tübingen, Germany) |
ASSIGNEE(S) | CureVac AG (Tübingen, Germany) |
INVENTOR(S) | Andreas Funkner (Tübingen, Germany); Stefanie Sewing (Tübingen, Germany); Isabel Strobel (Tübingen, Germany); Thorsten Mutzke (Tubingen, Germany) |
ABSTRACT | The present invention relates to methods for purifying RNA by chromatography under high salt conditions, e.g. by hydrophobic interaction chromatography. |
FILED | Tuesday, November 28, 2017 |
APPL NO | 16/464152 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/101 (20130101) C12N 15/1006 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279956 | Lynch et al. |
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FUNDED BY |
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APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
INVENTOR(S) | Michael David Lynch (Durham, North Carolina); Zhixia Ye (Raleigh, North Carolina) |
ABSTRACT | The present disclosure provides compositions and methods for rapid production of chemicals in genetically engineered microorganisms in a large scale. Also provided herein is a high-throughput metabolic engineering platform enabling the rapid optimization of microbial production strains. The platform, which bridges a gap between current in vivo and in vitro bio-production approaches, relies on dynamic minimization of the active metabolic network. |
FILED | Wednesday, October 23, 2019 |
APPL NO | 16/661065 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/001 (20130101) C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/0016 (20130101) C12N 9/0051 (20130101) C12N 9/1025 (20130101) C12N 15/746 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/42 (20130101) Original (OR) Class C12P 13/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280013 | Cox et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSAL ACHEMETAL TITANIUM, LLC (Cherry Hill, New Jersey) |
ASSIGNEE(S) | UNIVERSAL ACHEMETAL TITANIUM, LLC (Cherry Hill, New Jersey) |
INVENTOR(S) | James R. Cox (Cherry Hill, New Jersey); Chanaka L. De Alwis (Cherry Hill, New Jersey); Benjamin A. Kohler (Cherry Hill, New Jersey); Michael G. Lewis (Cherry Hill, New Jersey) |
ABSTRACT | A method to extract and refine metal products from metal-bearing ores, including a method to extract and refine titanium products. Titanium products can be extracted from titanium-bearing ores with TiO2 and impurity levels unsuitable for conventional methods. |
FILED | Tuesday, September 04, 2018 |
APPL NO | 16/121395 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Production and Refining of Metals; Pretreatment of Raw Materials C22B 34/1263 (20130101) C22B 34/1277 (20130101) Alloys C22C 14/00 (20130101) Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 3/28 (20130101) Original (OR) Class Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/20 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280016 | Palumbo et al. |
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FUNDED BY |
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APPLICANT(S) | INTEGRAN TECHNOLOGIES INC. (Mississauga, Canada) |
ASSIGNEE(S) | Integran Technologies Inc. (Mississauga, Canada) |
INVENTOR(S) | Gino Palumbo (Toronto, Canada); Leo Monaco (Toronto, Canada); Jonathan McCrea (Toronto, Canada); Klaus Tomantschger (Mississauga, Canada); Dave Limoges (Etobicoke, Canada); Michael Mills (Toronto, Canada) |
ABSTRACT | An apparatus and system for in-situ electropolishing and/or for in-situ electroforming a structural or functional reinforcement layer such as a sleeve of a selected metallic material on the internal surfaces of metallic tubular conduits are described. The apparatus and system can be employed on straight tubes, tube joints to different diameter tubes or face plates, tube elbows and other complex shapes encountered in piping systems. The apparatus includes components which can be independently manipulated and assembled on or near a degraded site and, after secured in place, form an electrolytic cell within the workpiece. The apparatus contains counter-electrodes which can be moved relative to the workpiece surface during the electroplating and/or electropolishing operation to provide flexibility in selecting and employing electropolishing process parameters and electroplating process parameters to design and optimize the surface roughness as well as the size, shape and properties of the electrodeposited reinforcing layer(s). |
FILED | Thursday, March 19, 2020 |
APPL NO | 16/824165 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/12 (20130101) C25D 3/38 (20130101) C25D 7/04 (20130101) Original (OR) Class Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor C25F 3/16 (20130101) C25F 7/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280490 | Bottiger et al. |
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FUNDED BY |
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APPLICANT(S) | Combat Capabilities Development Command, Chemical Biological Center (APG, Maryland) |
ASSIGNEE(S) | The United States of America as Represented by The Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Jerold R Bottiger (Aberdeen, Maryland); Jana S Kesavan (Catonsville, Maryland); Deborah R Schepers (Bel Air, Maryland) |
ABSTRACT | A system and method for generating combustion aerosols from liquid fuel. The system includes a furnace with an inner heating tube having a heating tape wrapped thereabout. Further, the system includes a fuel line extending through an inlet end of the heating tube and into the heating tube, and a means for dripping the liquid fuel onto a plurality of different locations on an inner surface of the heating tube. The system further includes a power supply to power the heating tape to heat the inner heating tube to a temperature which can ignite the liquid fuel dripped onto the inner surface of the inner heating tube whereby there is an immediate combustion to form combustion products. Finally, the system includes an air line connected to the heating tube for directing compressed air through the inner heating tube to mix with the combustion products and transport the formed combustion aerosols out of an outlet end of the inner heating tube. |
FILED | Wednesday, January 15, 2020 |
APPL NO | 16/743261 |
ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Methods of Steam Generation; Steam Boilers F22B 1/288 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280588 | Esquilin-Mangual et al. |
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FUNDED BY |
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APPLICANT(S) | United States of America as Represented by The Secretary of The Army (Alexandria, Virginia) |
ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
INVENTOR(S) | Omar Esquilin-Mangual (Vicksburg, Mississippi); Catherine S Stephens (Clinton, Mississippi); Omar G Flores (Vicksburg, Mississippi); Andrew B Edwards (Toney, Alabama); Erik M Chappell (Vicksburg, Mississippi) |
ABSTRACT | Ready armor modular protective systems that can be rapidly deployed in an urban environment. Exemplary armor systems include a container, and a wall assembly that fits inside of the container when in a collapsed configuration. The wall assembly includes a first end section, a second end section, a constraint mechanism, and first and second locking mechanisms. The first end section has a first space frame unit, and the second end section has second and third space frame units. A locking mechanism prevent relative vertical displacement from occurring between adjacent second and third space frame units. The constraint mechanism keeps the first and third space frame units at a fixed distance from one another. The constraint mechanism, when coupled with the first and third space frame units, keeps the locking mechanism from being removed from the second end section. |
FILED | Tuesday, September 29, 2020 |
APPL NO | 17/037480 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/3445 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/013 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280591 | Gallimore et al. |
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APPLICANT(S) | Harkind Dynamics, LLC (Denver, Colorado) |
ASSIGNEE(S) | Harkind Dynamics, LLC (Denver, Colorado) |
INVENTOR(S) | Craig Allen Gallimore (Denver, Colorado); Kelley Stewart Weiland (Fredericksburg, Virginia) |
ABSTRACT | An intelligent munition can position circuitry in a 12 gauge form factor that detects the distance from a target in real-time in order to deploy a parachute to slow the munition to a speed that is conducive to accurate, but non-lethal, deployment of at least one electrode toward the target. The munition can intelligently discharge electrical charge into the target via an electrode to disable the target. The munition may further monitor the target and deliver a subsequent electrical discharge in response to detected target movement. |
FILED | Tuesday, September 01, 2020 |
APPL NO | 17/009183 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 13/0031 (20130101) Original (OR) Class Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 7/02 (20130101) F42B 10/56 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280612 | Ayazi et al. |
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FUNDED BY |
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APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Farrokh Ayazi (Atlanta, Georgia); Haoran Wen (Atlanta, Georgia) |
ABSTRACT | An inertial measurement apparatus has mechanically bendable beams that have an isosceles trapezoid cross-section. The apparatus has a resonant member having a perimeter at least partially defined by a sidewall slanted at a first angular value and at least one electrode disposed adjacent, and parallel, to the sidewall and separated therefrom by a capacitive gap. |
FILED | Wednesday, March 25, 2020 |
APPL NO | 16/829327 |
ART UNIT | 2861 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/5642 (20130101) G01C 19/5747 (20130101) Original (OR) Class Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/241 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/097 (20130101) G01P 15/125 (20130101) G01P 2015/0848 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280613 | Ayazi et al. |
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FUNDED BY |
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APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Farrokh Ayazi (Atlanta, Georgia); Haoran Wen (Atlanta, Georgia) |
ABSTRACT | An inertial measurement apparatus has mechanically bendable beams that have an isosceles trapezoid cross-section. The apparatus has a resonant member having a perimeter at least partially defined by a sidewall slanted at a first angular value and at least one electrode disposed adjacent, and parallel, to the sidewall and separated therefrom by a capacitive gap. |
FILED | Wednesday, March 25, 2020 |
APPL NO | 16/829413 |
ART UNIT | 2861 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/5642 (20130101) G01C 19/5747 (20130101) Original (OR) Class Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/241 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/097 (20130101) G01P 15/125 (20130101) G01P 2015/0848 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280718 | Jalali et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Bahram Jalali (Los Angeles, California); Eric D. Diebold (Los Angeles, California); Brandon Buckley (Los Angeles, California) |
ABSTRACT | An imaging flow cytometry apparatus and method which allows registering multiple locations across a cell, and/or across multiple flow channels, in parallel using radio-frequency-tagged emission (FIRE) coupled with a parallel optical detection scheme toward increasing analysis throughput. An optical source is modulated by multiple RF frequencies to produce an optical interrogation beam having a spatially distributed beat frequency. This beam is directed to one or more focused streams of cells whose responsive fluorescence, in different frequencies, is registered in parallel by an optical detector. |
FILED | Monday, October 12, 2020 |
APPL NO | 17/068573 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) Original (OR) Class G01N 15/1459 (20130101) G01N 15/1484 (20130101) G01N 21/64 (20130101) G01N 21/6428 (20130101) G01N 21/6458 (20130101) G01N 21/6486 (20130101) G01N 33/537 (20130101) G01N 2015/1006 (20130101) G01N 2015/1477 (20130101) G01N 2021/6421 (20130101) G01N 2201/067 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280732 | Perera et al. |
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FUNDED BY |
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APPLICANT(S) | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Atlanta, Georgia) |
ASSIGNEE(S) | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Atlanta, Georgia) |
INVENTOR(S) | A. G. Unil Perera (Mableton, Georgia); Hemendra Mani Ghimire (Decatur, Georgia) |
ABSTRACT | The present disclosure relates to methods for the detection of melanoma and non-Hodgkin's lymphoma using attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy. Further disclosed are methods for treating melanoma and non-Hodgkin's lymphoma, based on differences in infrared absorbance. |
FILED | Tuesday, August 20, 2019 |
APPL NO | 16/545409 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0059 (20130101) A61B 5/444 (20130101) A61B 5/7257 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/35 (20130101) G01N 21/552 (20130101) Original (OR) Class G01N 2021/3595 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280797 | Mapstone et al. |
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FUNDED BY |
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APPLICANT(S) | Georgetown University (Washington, District of Columbia); University of Rochester (Rochester, New York) |
ASSIGNEE(S) | Georgetown University (Washington, District of Columbia); University of Rochester (Rochester, New York) |
INVENTOR(S) | Mark E. Mapstone (Irvine, California); Howard J. Federoff (Irvine, California); Massimo S. Fiandaca (Irvine, California); Amrita K. Cheema (Potomac, Maryland) |
ABSTRACT | The present invention relates to methods of determining if a subject has a decreased risk of suffering from future memory impairment. The methods comprise analyzing at least one plasma sample from the subject to determine a value of the subject's metabolite profile and comparing the value of the subject's metabolite profile with the value of a normal metabolite profile. A change in the value of the subject's metabolite profile, over normal values is indicative that the subject has a decreased risk of suffering from future memory impairment compared to a normal individual. |
FILED | Friday, February 02, 2018 |
APPL NO | 16/483260 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) Original (OR) Class G01N 2560/00 (20130101) G01N 2800/50 (20130101) G01N 2800/52 (20130101) G01N 2800/2814 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280856 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Connie H. Li (Alexandria, Virginia); Olaf M. J. van 't Erve (Falls Church, Virginia); Jeremy T. Robinson (Washington, District of Columbia); Ying Liu (Waterloo, Canada); Lian Li (Milwaukee, Wisconsin); Berend T. Jonker (Waldorf, Maryland) |
ABSTRACT | A device for directly electrically generating and detecting the current-generated spin polarization in topological insulators, comprising a first and fourth contact on a layer of Bi2Se3 and a second contact comprising a ferromagnet/oxide tunnel barrier contact as a detector, and a third contact comprising nonmagnetic metal as a reference contact, a current to the first and fourth contact to produce a net spin polarization, and the spin polarization manifesting as a voltage between the second (magnetic) and third (reference) contacts. |
FILED | Tuesday, October 27, 2020 |
APPL NO | 17/081575 |
ART UNIT | 2868 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/096 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/08 (20130101) H01L 43/10 (20130101) H01L 43/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280885 | Stann et al. |
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FUNDED BY |
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APPLICANT(S) | U.S. Army Combat Capabilities Development Command ARL ATTN: FCDD-RLL-CI (Adelphi, Maryland) |
ASSIGNEE(S) | America as represented by the Secretary of the Army (, None) |
INVENTOR(S) | Barry L. Stann (Edgewater, Maryland); Mark M. Giza (Kensington, Maryland) |
ABSTRACT | A system, device, apparatus and method for receiving a laser signal such as within a LADAR receiver. |
FILED | Monday, April 08, 2019 |
APPL NO | 16/377318 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4816 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11281028 | Phare et al. |
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FUNDED BY |
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APPLICANT(S) | Voyant Photonics, Inc. (Long Island City, New York) |
ASSIGNEE(S) | VOYANT PHOTONICS, INC. (New York, New York) |
INVENTOR(S) | Christopher T. Phare (Long Island City, New York); Steven A. Miller (Long Island City, New York); Viraj Shah (Long Island City, New York) |
ABSTRACT | Disclosed herein are systems and architecture for thermal waveguide-based phase shifters which improve thermal efficiency by having multi-pass waveguides arranged under the heating element in a serpentine fashion, with the waveguides having mismatched propagation constants. The combination allows for an increase in phase shift without increasing the length or the power consumption of the resistive heating element by increasing the total length of waveguide being heated by a singular heating element. |
FILED | Friday, March 20, 2020 |
APPL NO | 16/826051 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/011 (20130101) G02F 1/0147 (20130101) Original (OR) Class G02F 2203/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11281067 | Amin et al. |
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FUNDED BY |
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APPLICANT(S) | The George Washington University (Washington, District of Columbia) |
ASSIGNEE(S) | The George Washington University (Washington, District of Columbia) |
INVENTOR(S) | Rubab Amin (Fairfax, Virginia); Volker J. Sorger (Alexandria, Virginia) |
ABSTRACT | A photonic waveguide assembly has a first arm comprising a first photonic waveguide transmitting a first light, an optical refractive index modulator positioned about said first photonic waveguide to modulate the phase or amplitude, or combination thereof of the first light traveling in the first photonic waveguide; a second arm comprising a second photonic waveguide transmitting a second light; and a passive contact that contacts at least a portion of the second photonic waveguide of said second arm. |
FILED | Tuesday, August 20, 2019 |
APPL NO | 16/545733 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/025 (20130101) G02F 1/0157 (20210101) G02F 1/212 (20210101) G02F 1/225 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11281208 | Michael et al. |
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FUNDED BY |
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APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Nathan Michael (Pittsburgh, Pennsylvania); Xuning Yang (Pittsburgh, Pennsylvania); Koushil Sreenath (Pittsburgh, Pennsylvania) |
ABSTRACT | Described herein is a framework for efficient task-agnostic, user-independent adaptive teleoperation of mobile robots and remotely operated vehicles (ROV), including ground vehicles (including legged systems), aircraft, watercraft and spacecraft. The efficiency of a human operator is improved by minimizing the entropy of the control inputs, thereby minimizing operator energy and achieving higher performance in the form of smoother trajectories by concurrently estimating the user intent online and adaptively updating the action set available to the human operator. |
FILED | Monday, March 04, 2019 |
APPL NO | 16/291610 |
ART UNIT | 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/40 (20130101) G05B 2219/40174 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0016 (20130101) G05D 1/0038 (20130101) Original (OR) Class G05D 3/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11281429 | Jain et al. |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Shubham Jain (West Lafayette, Indiana); Anand Raghunathan (West Lafayette, Indiana); Sumeet Kumar Gupta (West Lafayette, Indiana) |
ABSTRACT | A ternary processing cell used as a memory cell and capable of in-memory arithmetic is disclosed which includes a first memory cell, adapted to hold a first digital value, a second memory cell, adapted to hold a second digital value, wherein a binary combination of the first digital value and the second digital value establishes a first ternary operand, a ternary input establishing a second ternary operand, and a ternary output, wherein the ternary output represents a multiplication of the first ternary operand and the second ternary operand. |
FILED | Wednesday, September 25, 2019 |
APPL NO | 16/581965 |
ART UNIT | 2825 — Semiconductors/Memory |
CURRENT CPC | Electric Digital Data Processing G06F 7/523 (20130101) Original (OR) Class G06F 17/16 (20130101) Computer Systems Based on Specific Computational Models G06N 3/063 (20130101) Static Stores G11C 11/412 (20130101) G11C 11/418 (20130101) G11C 11/419 (20130101) G11C 15/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11281815 | Gupta et al. |
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FUNDED BY |
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APPLICANT(S) | Siemens Industry Software Inc. (Plano, Texas); Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | Siemens Industry Software Inc. (Plano, Texas); Georgia Tech Reserch Corporation (Atlanta, Georgia) |
INVENTOR(S) | Ashish Gupta (Atlanta, Georgia); George Allen (Okinawa, Japan); Jaroslaw Rossignac (Atlanta, Georgia); Kelsey Kurzeja (Atlanta, Georgia); Suraj Ravi Musuvathy (Princeton Junction, New Jersey) |
ABSTRACT | A method, and corresponding systems and computer-readable mediums, for designing and manufacturing a part. A method includes receiving part data for a part to be manufactured. The method includes creating a set of balls and beams in a computer-aided design (CAD) model, in a patterning structure and based on the part data. The method includes constructing a steady lattice structure in the CAD model. The method includes displaying the CAD model including the steady lattice structure. |
FILED | Tuesday, February 05, 2019 |
APPL NO | 16/954850 |
ART UNIT | 2147 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 50/00 (20141201) Electric Digital Data Processing G06F 30/10 (20200101) Original (OR) Class G06F 2119/18 (20200101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11281905 | Yakimenko |
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APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Oleg A. Yakimenko (Seaside, California) |
ABSTRACT | A computer-based system and method allows a user to automatically aerially inspect a selected runway/taxiway/tarmac surface for foreign object debris (FOD) using a plurality of UAVs equipped with electro-optical (EO) sensors. Live images of the runway surface captured by the EO sensors are transmitted from the UAVs during an inspection sweep of the runway surface and are compared with FOD-free reference images of the runway surface to determine whether candidate FOD are detected on the runway surface. Information about and images of candidate FOD are displayed to the user allowing the user to determine whether to send a team to remove the FOD from the runway. |
FILED | Thursday, September 12, 2019 |
APPL NO | 16/568462 |
ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/127 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0027 (20130101) G05D 1/042 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00637 (20130101) Original (OR) Class G06K 9/3233 (20130101) Image Data Processing or Generation, in General G06T 7/0002 (20130101) G06T 7/97 (20170101) G06T 7/337 (20170101) G06T 2210/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11282249 | Lin et al. |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Chung-Ching Lin (White Plains, New York); Sharathchandra U. Pankanti (Fairfield County, Connecticut); Karthikeyan Natesan Ramamurthy (Pleasantville, New York); Aleksandr Y. Aravkin (Seattle, Washington); John R. Smith (New York, New York) |
ABSTRACT | A method and system of stitching a plurality of image views of a scene, including grouping matched points of interest in a plurality of groups, and determining a similarity transformation with smallest rotation angle for each grouping of the matched points. The method further includes generating virtual matching points on non-overlapping area of the plurality of image views and generating virtual matching points on overlapping area for each of the plurality of image views. |
FILED | Monday, January 20, 2020 |
APPL NO | 16/747511 |
ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0063 (20130101) G06K 9/4609 (20130101) G06K 9/4638 (20130101) G06K 9/4671 (20130101) G06K 9/6211 (20130101) G06K 2009/2045 (20130101) G06K 2009/6213 (20130101) Image Data Processing or Generation, in General G06T 3/4038 (20130101) G06T 5/006 (20130101) G06T 7/33 (20170101) G06T 11/60 (20130101) Original (OR) Class G06T 2207/10032 (20130101) G06T 2207/20104 (20130101) G06T 2207/20221 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11282620 | DeBry et al. |
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FUNDED BY |
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APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
ASSIGNEE(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
INVENTOR(S) | Kyle DeBry (Columbus, Ohio); Gregory Lafyatis (Columbus, Ohio) |
ABSTRACT | An example method for connectorizing a superconducting cable is described herein. The method can include depositing an oxide layer on a surface of a superconducting cable, electroplating a metal layer on the surface of the superconducting cable, and soldering a connector to the metal layer coated on the surface of the superconducting cable. The oxide layer allows the metal layer to adhere to the surface of the superconducting cable. |
FILED | Monday, March 11, 2019 |
APPL NO | 16/298509 |
ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 12/06 (20130101) H01B 13/222 (20130101) Original (OR) Class Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 24/40 (20130101) H01R 43/02 (20130101) Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines H02G 15/34 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11282703 | Claridge et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Shelley A. Claridge (Lafayette, Indiana); Ashlin Porter (Lafayette, Indiana) |
ABSTRACT | The present invention generally relates to a method for preparing structurally unique nanomaterials and the products thereof. In particular, the present invention discloses a method for preparing an array of ultra-narrow nanowire or nanorod on a patterned monolayer supported by a 2D material substrate in a controlled environment, wherein said pattered monolayer comprises a polymerizable amphiphiles such as phospholipid with a terminal amine and wherein said controlled environment comprises a major nonpolar solvent, a trace amount of polar solvent, and a unsaturated aliphatic amine. Gold nanowires (AuNWs) so prepared have a highly controlled diameter of about 2 nm, a length up to about 1000 nm, and an AuNW ordering over an area >100 μm2. |
FILED | Friday, March 13, 2020 |
APPL NO | 16/818857 |
ART UNIT | 2818 — Semiconductors/Memory |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02425 (20130101) H01L 21/02603 (20130101) Original (OR) Class H01L 21/02628 (20130101) H01L 21/02658 (20130101) H01L 29/0669 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11283012 | Williams |
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FUNDED BY |
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APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
INVENTOR(S) | R. Stanley Williams (Portola Valley, California) |
ABSTRACT | An electrically actuated switch comprises a first electrode, a second electrode, and an active region disposed therebetween. The active region comprises at least one primary active region comprising at least one material that can be doped or undoped to change its electrical conductivity, and a secondary active region comprising at least one material for providing a source/sink of ionic species that act as dopants for the primary active region(s). Methods of operating the switch are also provided. |
FILED | Monday, August 05, 2019 |
APPL NO | 16/532096 |
ART UNIT | 2893 — Semiconductors/Memory |
CURRENT CPC | Static Stores G11C 13/0007 (20130101) G11C 13/0009 (20130101) G11C 2213/52 (20130101) G11C 2213/53 (20130101) G11C 2213/56 (20130101) G11C 2213/77 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/2463 (20130101) H01L 45/08 (20130101) Original (OR) Class H01L 45/14 (20130101) H01L 45/145 (20130101) H01L 45/146 (20130101) H01L 45/147 (20130101) H01L 45/1206 (20130101) H01L 45/1233 (20130101) Pulse Technique H03K 17/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11283020 | Tsui et al. |
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FUNDED BY |
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APPLICANT(S) | UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico) |
ASSIGNEE(S) | UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico) |
INVENTOR(S) | Lok-kun Tsui (Albuquerque, New Mexico); John Bryan Plumley (Albuquerque, New Mexico); Fernando Garzon (Santa Fe, New Mexico); Benjamin J. Brownlee (WPAFB, Ohio); Thomas L. Peng (WPAFB, Ohio) |
ABSTRACT | An resistive switch having a first platinum layer, an electrolyte layer that is formed by extrusion based additive manufacturing, a silver layer, and a second platinum layer, and methods of manufacturing and using the resistive switch. |
FILED | Friday, February 14, 2020 |
APPL NO | 16/792054 |
ART UNIT | 2824 — Semiconductors/Memory |
CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Static Stores G11C 13/0011 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 45/146 (20130101) H01L 45/148 (20130101) H01L 45/1633 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11283106 | Yersak et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, a body corporate (Denver, Colorado) |
ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
INVENTOR(S) | Thomas A. Yersak (San Diego, California); Se-Hee Lee (Louisville, Colorado); Conrad Stoldt (Golden, Colorado) |
ABSTRACT | An all-solid-state lithium battery, thermo-electromechanical activation of Li2S in sulfide based solid state electrolyte with transition metal sulfides, and electromechanical evolution of a bulk-type all-solid-state iron sulfur cathode, are disclosed. An example all-solid-state lithium battery includes a cathode having a transition metal sulfide mixed with elemental sulfur to increase electrical conductivity. In one example method of in-situ electromechanically synthesis of Pyrite (FeS2) from Sulfide (FeS) and elemental sulfur (S) precursors for operation of a solid-state lithium battery, FeS+S composite electrodes are cycled at moderately elevated temperatures. |
FILED | Wednesday, November 27, 2019 |
APPL NO | 16/698066 |
ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/364 (20130101) H01M 4/382 (20130101) H01M 4/386 (20130101) H01M 4/5815 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0068 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11283142 | Tomasic et al. |
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FUNDED BY |
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APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
ASSIGNEE(S) | United States of America has represented by the Secretary of the Air Force (Wright-Petterson, Ohio) |
INVENTOR(S) | Boris Tomasic (Harvard, Massachusetts); Carl R. Pfeiffer (Beavercreek, Ohio); Thomas P. Steffen (Xenia, Ohio) |
ABSTRACT | A linear-to-circular polarizer antenna is disclosed. In accordance with embodiments of the invention, the polarizer antenna includes an antenna operable to transmit and receive polarized signals and a linear-to-circular polarizer coupled to the antenna. The polarizer includes a plurality of cascaded elements, waveplates or anisotropic sheets, having biaxial permittivity. Each cascaded element has a principal axis rotated at different angles relative to an adjacent element about a z-axis of a 3-dimensional x, y, z coordinate system, and each element is composed of an artificial anisotropic dielectric. The polarizer further includes impedance matching layers disposed adjacent the cascaded elements. |
FILED | Wednesday, November 28, 2018 |
APPL NO | 16/202684 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/286 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/17 (20130101) Original (OR) Class H01P 1/171 (20130101) H01P 1/172 (20130101) H01P 1/173 (20130101) H01P 11/00 (20130101) Antennas, i.e Radio Aerials H01Q 3/40 (20130101) H01Q 3/2676 (20130101) H01Q 5/335 (20150115) H01Q 15/04 (20130101) H01Q 15/24 (20130101) H01Q 15/244 (20130101) H01Q 15/246 (20130101) H01Q 21/0031 (20130101) H01Q 21/064 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11283176 | Boryssenko |
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FUNDED BY |
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APPLICANT(S) | SI2 Technologies, Inc. (North Billerica, Massachusetts) |
ASSIGNEE(S) | SI2 Technologies, Inc. (North Billerica, Massachusetts) |
INVENTOR(S) | Anatoliy Boryssenko (Belchertown, Massachusetts) |
ABSTRACT | Antenna elements are described that may include a radiator, a feeding portion, a first impedance transformer, a balun, and a second impedance transformer. The first impedance transformer, balun, and second impedance transformer may be disposed above a ground plane of an antenna array to reduce a bulk of the array. The array can also include a dielectric top layer for loading apertures of the antenna array. The antenna elements can also include anomaly suppressors can be provided to cancel common-mode resonances from the radiators. |
FILED | Monday, July 13, 2020 |
APPL NO | 16/927827 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 9/16 (20130101) Original (OR) Class H01Q 9/065 (20130101) H01Q 21/0006 (20130101) H01Q 21/062 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11283241 | Laurain et al. |
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FUNDED BY |
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APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
ASSIGNEE(S) | Arizona Board of Regents on behalf of University of Arizona (Tucson, Arizona) |
INVENTOR(S) | Alexandre Laurain (Tucson, Arizona); Jerome V. Moloney (Tucson, Arizona); Patrick Kokou Gbele (Tucson, Arizona) |
ABSTRACT | A reflector for optical devices is disclosed. The reflector includes a distributed Bragg reflector and a metal reflector. The metal reflector is contained within one or more apertures defined by a material having good adliesion to a semiconductor material. A method for bonding the resulting structure to a heat spreader is also disclosed. |
FILED | Thursday, December 07, 2017 |
APPL NO | 16/464147 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/14 (20130101) H01S 5/041 (20130101) H01S 5/187 (20130101) H01S 5/0216 (20130101) H01S 5/02484 (20130101) H01S 5/3432 (20130101) H01S 5/18377 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11283265 | Robinson et al. |
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FUNDED BY |
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APPLICANT(S) | Galvion Soldier Power, LLC (Southborough, Massachusetts) |
ASSIGNEE(S) | GALVION SOLDIER POWER, LLC (Southborough, Massachusetts) |
INVENTOR(S) | Philip T. Robinson (Harvard, Massachusetts); Seth M. Dziengeleski (Southbridge, Massachusetts); James D. Kazmierczak (Marlborough, Massachusetts); David J. Holigan (Atkinson, New Hampshire) |
ABSTRACT | Various aspects of invention provide portable power manager operating methods. One aspect of the invention provides a method for operating a power manager having a plurality of device ports for connecting with external power devices and a power bus for connecting with each device port. The method includes: disconnecting each device port from the power bus when no external power device is connected to the device port; accessing information from newly connected external power devices; determining if the newly connected external power devices can be connected to the power bus without power conversion; if not, determining if the newly connected external power devices can be connected to the power bus over an available power converter; and if so, configuring the available power converter for suitable power conversion. |
FILED | Wednesday, May 08, 2019 |
APPL NO | 16/406750 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Electric Digital Data Processing G06F 1/263 (20130101) G06F 1/266 (20130101) G06F 1/3287 (20130101) G06F 13/4022 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 1/00 (20130101) H02J 4/00 (20130101) Original (OR) Class H02J 5/00 (20130101) H02J 7/0021 (20130101) H02J 7/0027 (20130101) H02J 7/00036 (20200101) H02J 7/00045 (20200101) H02J 7/0068 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/04 (20130101) H02M 5/04 (20130101) H02M 7/04 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/00 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11283486 | McKnight et al. |
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FUNDED BY |
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APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
INVENTOR(S) | Geoffrey P. McKnight (Los Angeles, California); Walter S. Wall (Los Angeles, California); Skyler Selvin (San Jose, California); Casey J. Sennott (Calabasas, California); David W. Shahan (Malibu, California) |
ABSTRACT | A mechanically actuated transmitter is disclosed. The transmitter can comprise a magnetoelastic member; a magnet adjacent to the magnetoelastic member for inducing magnetization in the magnetoelastic member; a mechanical driver for applying mechanical stress to the magnetoelastic material, thereby changing the magnetic permeability of the magnetoelastic material to change an external magnetic field. |
FILED | Wednesday, April 24, 2019 |
APPL NO | 16/393852 |
ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Transmission H04B 5/0075 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11283496 | Chang et al. |
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FUNDED BY |
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APPLICANT(S) | Vencore Labs, Inc. (Basking Ridge, New Jersey) |
ASSIGNEE(S) | PERSPECTA LABS INC. (Basking Ridge, New Jersey) |
INVENTOR(S) | Nicholas Chang (Basking Ridge, New Jersey); Eddie Fung (Basking Ridge, New Jersey); James Hodge (Basking Ridge, New Jersey) |
ABSTRACT | A computer-implemented method, a computer program product, and a system include a processor(s) that produces a set of beamforming vectors, each vector produced based on a distinct set of parameters. To produce vector of the vectors, the processor(s) obtains, from receive antennas, data comprising a waveform comprising slots with boundaries, from a first collection window. The processor(s) determines the parameters (e.g., silent portion length and signal portion length) and determines which slots of the waveform contain signal operating instructions. The processor(s) aligns the slot boundaries, utilizing the data, based on determining which slots of the waveform contain signal operating instructions. The processor(s) extracts the signal portion and the silent portion, determines a covariance for each, and determines a vector and eigenvalue. From the set, the processor(s) selects a vector and applies the vector to a second collection window to suppress interference in data received within the second collection window. |
FILED | Wednesday, December 19, 2018 |
APPL NO | 16/225478 |
ART UNIT | 2636 — Optical Communications |
CURRENT CPC | Transmission H04B 1/10 (20130101) H04B 7/086 (20130101) H04B 7/0434 (20130101) Original (OR) Class H04B 7/0617 (20130101) H04B 7/0857 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 25/0204 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US D946743 | Sorna et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
INVENTOR(S) | Mark Sorna (Silverdale, Washington); Jacob Yates (Poulsbo, Washington) |
ABSTRACT | |
FILED | Friday, August 07, 2020 |
APPL NO | 29/742295 |
ART UNIT | 2919 — Design |
CURRENT CPC | Medical and laboratory equipment D24/110.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US D946744 | Sorna et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
INVENTOR(S) | Mark Sorna (Silverdale, Washington); Jacob Yates (Poulsbo, Washington) |
ABSTRACT | |
FILED | Friday, August 07, 2020 |
APPL NO | 29/742296 |
ART UNIT | 2919 — Design |
CURRENT CPC | Medical and laboratory equipment D24/110.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US D946745 | Sorna et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
INVENTOR(S) | Mark Sorna (Silverdale, Washington); Jacob Yates (Poulsbo, Washington) |
ABSTRACT | |
FILED | Friday, August 07, 2020 |
APPL NO | 29/742297 |
ART UNIT | 2919 — Design |
CURRENT CPC | Medical and laboratory equipment D24/110.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US D946746 | Sorna et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
INVENTOR(S) | Mark Sorna (Silverdale, Washington); Jacob Yates (Poulsbo, Washington) |
ABSTRACT | |
FILED | Friday, August 07, 2020 |
APPL NO | 29/742298 |
ART UNIT | 2919 — Design |
CURRENT CPC | Medical and laboratory equipment D24/110.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
US 11278025 | Ausubel et al. |
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FUNDED BY |
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APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); Rhode Island Hospital, A Lifespan-Partner (Providence, Rhode Island); Temple University-Of The Commonwealth System Of Higher Education (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); Rhode Island Hospital, A Lifespan-Partner (Providence, Rhode Island); Temple University-Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
INVENTOR(S) | Frederick M. Ausubel (Newton, Massachusetts); Wooseong Kim (Providence, Rhode Island); Eleftherios Mylonakis (Providence, Rhode Island); William M. Wuest (Atlanta, Georgia) |
ABSTRACT | The present application provides compounds and methods of treating bacterial infection, including bacterial infection caused by P. acnes. |
FILED | Thursday, May 17, 2018 |
APPL NO | 16/614251 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 31/08 (20130101) Original (OR) Class A01N 37/38 (20130101) A01N 37/40 (20130101) A01N 43/16 (20130101) A01N 43/16 (20130101) A01N 63/50 (20200101) A01N 63/50 (20200101) Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Acyclic or Carbocyclic Compounds C07C 39/17 (20130101) C07C 65/11 (20130101) C07C 65/17 (20130101) C07C 235/66 (20130101) C07C 2603/74 (20170501) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278222 | Moeller et al. |
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FUNDED BY |
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APPLICANT(S) | Giner, Inc. (Newton, Massachusetts) |
ASSIGNEE(S) | 1A SMART START LLC (Grapevine, Texas) |
INVENTOR(S) | Michael Moeller (Boston, Massachusetts); Brian Rasimick (Boston, Massachusetts) |
ABSTRACT | Waterless electrochemical transdermal alcohol sensor. In one embodiment, the sensor includes a proton exchange membrane imbibed with an imbibing liquid that includes at least one cationic substance that is liquid at room temperature. As examples, the cationic substance may be one or more ionic liquids with an imidazolium, phosphonium, ammonium, pyridinium, pyrrolidinium, or sulfonium backbone structure. The imbibing of the proton exchange membrane with the cationic substance obviates the need for the periodic addition of water to the electrochemical cell. The sensor additionally includes a sensing electrode, which is bonded to one side of the proton exchange membrane, and a counter electrode and a reference electrode, both of which are bonded to the opposite side of the proton exchange membrane. The sensor may be incorporated into a wearable transdermal alcohol sensor device, which, in turn, may be incorporated into a system for detecting transdermal alcohol. |
FILED | Monday, February 12, 2018 |
APPL NO | 15/894255 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/681 (20130101) A61B 5/1477 (20130101) Original (OR) Class A61B 5/4845 (20130101) A61B 5/14546 (20130101) A61B 2560/0252 (20130101) A61B 2562/125 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/40 (20130101) G01N 27/403 (20130101) G01N 27/407 (20130101) G01N 27/4074 (20130101) G01N 33/4972 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278226 | Heydari et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California); University of Southern California (Los Angeles, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
INVENTOR(S) | Payam Heydari (Irvine, California); Zoran Nenadic (Irvine, California); An Do (Orange, California); Charles Liu (Los Angeles, California) |
ABSTRACT | A fully-implantable brain-computer interface cyber-physical system capable of acquiring and analyzing electrocorticogram (“ECoG”) signals, recorded directly from the subdural space of the brain, to enable direct brain control of a prosthetic (e.g., a robotic gait exoskeleton or a functional electrical stimulation (“FES”) system) is disclosed. The present system comprises a plurality of electrodes, for acquiring the ECoG signals, and a digital signal processor (“DSP”) for deriving a plurality of real-time commands from the ECoG signals. These real-time commands may then be wirelessly transmitted to the prosthetic for execution. Further, to avoid wireless data transmission of the ECoG signals from the plurality of electrodes to the DSP, which would expose the brain, skull, and scalp tissue to potentially harmful radio frequencies, a subcutaneous tunneling cable operatively couples the plurality of electrodes and the DSP. |
FILED | Friday, April 05, 2019 |
APPL NO | 16/376831 |
ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/24 (20210101) Original (OR) Class A61B 5/30 (20210101) A61B 5/369 (20210101) A61B 5/4851 (20130101) A61B 5/6868 (20130101) A61B 5/7225 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/72 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 2201/165 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0534 (20130101) Electric Digital Data Processing G06F 3/00 (20130101) G06F 3/01 (20130101) G06F 3/015 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278247 | Trayanova et al. |
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FUNDED BY |
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APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
INVENTOR(S) | Natalia A. Trayanova (Baltimore, Maryland); Adityo Prakosa (Baltimore, Maryland); Mark Cartoski (Parkville, Maryland); Patrick M. Boyle (Baltimore, Maryland) |
ABSTRACT | An embodiment in accordance with the present invention provides a non-invasive solution to risk stratify the risk of in arrhythmia in patients with TOF. Currently, no reliable method for non-invasive risk stratification exists. In the realm of congenital heart disease, cardiac MRI is now used routinely for patients with Tetralogy of Fallot (TOF), the most common form of cyanotic congenital heart disease. An innovative platform for using clinical MRI data to create 3D electromechanical models of the heart enables predictions of whether or not patients with ischemic heart disease have the substrate for arrhythmia and what their relative risk for such an event is. An embodiment of the current invention provides a non-invasive solution to risk stratify the risk of arrhythmia in patients with TOF. Currently, no reliable method for non-invasive risk stratification exists. |
FILED | Monday, November 06, 2017 |
APPL NO | 16/347385 |
ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0044 (20130101) A61B 5/055 (20130101) A61B 5/7207 (20130101) A61B 5/7264 (20130101) A61B 5/7275 (20130101) Original (OR) Class A61B 2576/023 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5601 (20130101) G01R 33/5608 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 50/30 (20180101) G16H 50/50 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278254 | Pan et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | THE UNIVERSITY OF CHICAGO (Chicago, Illinois) |
INVENTOR(S) | Xiaochuan Pan (Chicago, Illinois); Buxin Chen (Chicago, Illinois); Zheng Zhang (Chicago, Illinois); Emil Sidky (Chicago, Illinois); Dan Xia (Chicago, Illinois) |
ABSTRACT | A multi-spectral tomography imaging system includes one or more source devices configured to direct beams of radiation in multiple spectra to a region of interest (ROI), and one or more detectors configured to receive the beams of radiation. The system includes a processor configured to cause movement in at least one of the components such that a first beam of radiation with a first spectrum is directed to the ROI for less than 360 degrees of movement of the ROI. The processor is also configured to process data detected by the one or more detectors, where the data results at least in part from the first beam of radiation with the first spectrum that is directed to the ROI for less than the 360 degrees of movement of the ROI. The processor is further configured to generate an image of the ROI based on the processed data. |
FILED | Friday, September 21, 2018 |
APPL NO | 16/648375 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/08 (20130101) A61B 6/032 (20130101) A61B 6/469 (20130101) Original (OR) Class A61B 6/482 (20130101) A61B 6/4064 (20130101) A61B 6/5205 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278289 | Goldie et al. |
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FUNDED BY |
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APPLICANT(S) | Vivonics, Inc. (Bedford, Massachusetts) |
ASSIGNEE(S) | Vivonics, Inc. (Bedford, Massachusetts) |
INVENTOR(S) | James H. Goldie (Lexington, Massachusetts); Brendan LaBrecque (Middleton, Massachusetts); Anna M Galea (Stow, Massachusetts); Eric Klem (Lexington, Massachusetts); Thomas Doyle (Brentwood, Tennessee); Ian Cohen (Broomfield, Colorado); Tim Robinson (Sandown, New Hampshire) |
ABSTRACT | A pulmonary artery flow restrictor system includes a funnel shaped membrane with a proximal base and a restrictive distal opening which is stretchable to larger sizes. A self-expanding frame is attached to the proximal base of the membrane for securing the membrane within the pulmonary artery. |
FILED | Friday, December 27, 2019 |
APPL NO | 16/728028 |
ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/12036 (20130101) Original (OR) Class A61B 17/12109 (20130101) A61B 17/12172 (20130101) A61B 17/12177 (20130101) A61B 2017/12054 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/82 (20130101) A61F 2002/068 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 29/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278474 | Yelick et al. |
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APPLICANT(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Cambridge, Massachusetts) |
ASSIGNEE(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Cambridge, Massachusetts) |
INVENTOR(S) | Pamela C Yelick (Boston, Massachusetts); Ali Khademhosseini (Cambridge, Massachusetts) |
ABSTRACT | A dental tissue regenerative composition. The composition includes a combination of (1) human dental pulp stem cells and (2) at least one of human umbilical vein endothelial cells or vascular endothelial growth factor. The combination is encapsulated in a light-activated gelatin methacrylate hydrogel. |
FILED | Friday, December 01, 2017 |
APPL NO | 15/777304 |
ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 5/40 (20170201) Preparations for Medical, Dental, or Toilet Purposes A61K 6/56 (20200101) A61K 6/62 (20200101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278497 | Zhou et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Qi Zhou (West Lafayette, Indiana); Sharad Mangal (West Lafayette, Indiana) |
ABSTRACT | The present disclosure generally relates to a process for manufacturing a dry powder composition, particularly to a co-sprayed colistin and meropenem dry powder inhaler for the treatment of various bacterial infections. Methods of use and composition matters are within the scope of this disclosure. |
FILED | Friday, April 26, 2019 |
APPL NO | 16/395303 |
ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0075 (20130101) A61K 9/1688 (20130101) Original (OR) Class A61K 31/407 (20130101) A61K 38/12 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278505 | Richmond et al. |
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FUNDED BY |
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APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | Jillian M. Richmond (Dayville, Connecticut); John E. Harris (Sterling, Massachusetts); James Pennock Strassner (Worcester, Massachusetts) |
ABSTRACT | Methods of diagnosing and treating vitiligo. |
FILED | Tuesday, April 24, 2018 |
APPL NO | 16/608116 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/00 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278518 | Bollyky et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Paul L. Bollyky (Palo Alto, California); Nadine Nagy (Palo Alto, California); Kevin Vincent Grimes (Palo Alto, California) |
ABSTRACT | 4-methylumbelliferone is useful for the treatment of autoimmune diseases, such as primary sclerosing cholangitis (PSC). |
FILED | Tuesday, May 21, 2019 |
APPL NO | 16/418727 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/353 (20130101) Original (OR) Class A61K 31/7048 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278522 | Kellar et al. |
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FUNDED BY |
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APPLICANT(S) | Georgetown University (Washington, District of Columbia) |
ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
INVENTOR(S) | Kenneth J. Kellar (Bethesda, Maryland); Yingxian Xiao (Potomac, Maryland); Patrick A. Forcelli (Washington, District of Columbia) |
ABSTRACT | Previous studies (Xiao et al., 2001) have identified two metabolites of methadone, EMDP (2-ethyl-5-methyl-3,3-diphenyl-1-pyrroline) and EDDP (2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine), which are considered to be inactive at opiate receptors, as relatively potent noncompetitive channel blockers of α3β4 nAChRs. We have now evaluated these compounds in rats and mice in preclinical behavioral models predictive of potential anxiolytic and antidepressant efficacy. We found that EMDP, but not EDDP, displayed robust effects predictive of anxiolytic and antidepressant efficacy without significant effects on locomotor activity. Moreover, EMDP at behaviorally active doses, unlike mecamylamine, did not produce eyelid ptosis, suggesting it may produce fewer autonomic side effects than mecamylamine. Thus, the methadone metabolite EMDP may represent a novel therapeutic avenue for the treatment of some affective disorders. |
FILED | Monday, July 13, 2020 |
APPL NO | 16/927544 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/40 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/22 (20180101) A61P 25/24 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278527 | Haass-Koffler |
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APPLICANT(S) | Brown University (Providence, Rhode Island) |
ASSIGNEE(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
INVENTOR(S) | Carolina L. Haass-Koffler (Providence, Rhode Island) |
ABSTRACT | Stress responses involve corticotropin releasing factor (CRF), the two cognate receptors (CRF1 and CRF2) and the CRF-binding protein (CRFBP). Utilizing a novel cell-based assay, a C-terminal CRFBP fragment [CRFBP(10 kD)] was found to potentiates CRF-intracellular Ca2+ release, demonstrating that CRFBP possesses excitatory roles in addition to the inhibitory role established by the N-terminal fragment of CRFBP [CRFBP(27 kD)]. This interaction was CRF2-specific, as CRF1 responses were not potentiated by CRFBP(10 kD). As there were currently no small molecule ligands available that selectively interact with either CRFBP or CRF2, a cell-based assay was miniaturized, wherein CRFBP(10 kD) was fused as a chimera with CRF2α, that allowed us to a perform a high-throughput screen (HTS) of approximately 350,000 small molecules. This resulted in the identification of negative allosteric modulators (NAMs) of the CRFBP(10 kD)-CRF2 complex that blunt CRF-induced potentiation of N-Methyl-D-aspartic acid receptor (NMDAR)-mediated synaptic transmission in dopamine neurons in the ventral tegmental area (VTA). These results provide the first evidence of specific roles for CRF2 and CRFBP in the modulation of neuronal activity and suggest that NMDARs in the VTA may be a target for the treatment of stress and substance abuse disorders such as alcohol use disorder. |
FILED | Wednesday, September 04, 2019 |
APPL NO | 17/273607 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) A61K 31/4245 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278550 | Jiang et al. |
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FUNDED BY |
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APPLICANT(S) | Duke University (Durham, North Carolina); The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina); The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
INVENTOR(S) | Yong-hui Jiang (Durham, North Carolina); Yuna Kim (Durham, North Carolina); Hyeong-min Lee (Chapel Hill, North Carolina); Jian Jin (New York, New York); Bryan L. Roth (Durham, North Carolina) |
ABSTRACT | The invention provides pharmaceutical compositions and methods of use thereof for treating Prader-Willi syndrome. More specifically, the invention provides pharmaceutical compositions that when administered inhibit the G9a driven methylation of histone H3 lysine 9. |
FILED | Wednesday, May 17, 2017 |
APPL NO | 16/301511 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) Original (OR) Class A61K 31/551 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) Heterocyclic Compounds C07D 401/02 (20130101) C07D 401/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278551 | Smith et al. |
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FUNDED BY |
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APPLICANT(S) | GEORGETOWN UNIVERSITY (Washington, District of Columbia) |
ASSIGNEE(S) | GEORGETOWN UNIVERSITY (Washington, District of Columbia) |
INVENTOR(S) | Jill P. Smith (Camp Hill, Pennsylvania); Louis Weiner (Washington, District of Columbia); Sandra Jablonski (Silver Spring, Maryland); Sandeep Nadella (Alexandria, Virginia); Shangzi Wang (Derwood, Maryland) |
ABSTRACT | Provided herein are methods for treating a cholecystokinin (CCK) receptor-expressing cancerous tumor in a subject. The methods comprising administering to the subject an effective amount of a CCK receptor inhibitor and an effective amount of an immune checkpoint inhibitor, wherein the CCK receptor inhibitor inhibits one or more CCK receptors selected from the group consisting of a CCK-A receptor, a CCK-B receptor and a CCK-C receptor, and wherein the immune checkpoint inhibitor is a programmed cell death protein 1 (PD1) inhibitor or a cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) inhibitor. |
FILED | Thursday, March 15, 2018 |
APPL NO | 16/493882 |
ART UNIT | 1699 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/198 (20130101) A61K 31/5513 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278554 | Bertozzi et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Carolyn Ruth Bertozzi (Berkeley, California); Nicholas J. Agard (Berkeley, California); Jennifer A. Prescher (Berkeley, California); Jeremy Michael Baskin (Berkeley, California); Ellen May Sletten (Berkeley, California) |
ABSTRACT | The present invention provides modified cycloalkyne compounds; and method of use of such compounds in modifying biomolecules. The present invention features a cycloaddition reaction that can be carried out under physiological conditions. In general, the invention involves reacting a modified cycloalkyne with an azide moiety on a target biomolecule, generating a covalently modified biomolecule. The selectivity of the reaction and its compatibility with aqueous environments provide for its application in vivo (e.g., on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids). |
FILED | Monday, October 07, 2019 |
APPL NO | 16/595002 |
ART UNIT | 1699 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/655 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 45/63 (20130101) C07C 45/63 (20130101) C07C 45/292 (20130101) C07C 45/292 (20130101) C07C 45/511 (20130101) C07C 45/511 (20130101) C07C 45/511 (20130101) C07C 45/511 (20130101) C07C 49/457 (20130101) C07C 49/457 (20130101) C07C 49/457 (20130101) C07C 49/573 (20130101) C07C 49/753 (20130101) C07C 49/753 (20130101) C07C 49/753 (20130101) C07C 57/26 (20130101) C07C 59/72 (20130101) C07C 63/66 (20130101) C07C 63/74 (20130101) C07C 69/76 (20130101) C07C 69/708 (20130101) C07C 2601/18 (20170501) Heterocyclic Compounds C07D 207/416 (20130101) C07D 207/452 (20130101) C07D 249/16 (20130101) C07D 495/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/531 (20130101) G01N 33/6803 (20130101) G01N 33/6842 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278556 | Voelker |
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FUNDED BY |
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APPLICANT(S) | National Jewish Health (Denver, Colorado) |
ASSIGNEE(S) | National Jewish Health (Denver, Colorado) |
INVENTOR(S) | Dennis R. Voelker (Littleton, Colorado) |
ABSTRACT | The invention generally relates to methods to prevent and/or inhibit viral infection as well as to inhibit inflammation and/or pathogen infection by administering at least one xylitol lipid analog or compositions comprising at least one xylitol lipid analog to an individual. The invention also relates to methods to prevent or inhibit respiratory syncytial virus (RSV) infection by administering at least one xylitol lipid analog or compositions comprising at least one xylitol lipid analog to an individual. |
FILED | Tuesday, February 27, 2018 |
APPL NO | 16/488865 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 31/683 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278572 | Gao et al. |
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FUNDED BY |
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APPLICANT(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
INVENTOR(S) | Jiliang Gao (Potomac, Maryland); Philip M. Murphy (Rockville, Maryland); David H. McDermott (Olney, Maryland); Marie Siwicki (Washington, District of Columbia); Harry L. Malech (Bethesda, Maryland); Joy Liu (Boyds, Maryland); Paejonette Jacobs (Bronx, New York) |
ABSTRACT | Provided herein are methods of enhancing engraftment of hematopoietic stem cells (HSC) in recipient subjects by reducing expression (or activity) of CXC chemokine receptor 4 (CXCR4). Such methods can be used in gene therapy protocols and in HSC transplantation, for example allowing this to occur without radiation or chemotherapy conditioning as is typically done in non-myeloablative HSC transplant. In some examples, gene editing methods are used to delete one copy of the CXCR4 gene before HSC or bone marrow transplantation, enhancing the efficiency and durability of donor cell repopulation. |
FILED | Friday, July 17, 2015 |
APPL NO | 15/324219 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/54 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278594 | Jensen |
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FUNDED BY |
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APPLICANT(S) | City of Hope (Duarte, California) |
ASSIGNEE(S) | City of Hope (Duarte, California) |
INVENTOR(S) | Michael Jensen (Duarte, California) |
ABSTRACT | The present invention relates to chimeric transmembrane immunoreceptors, named “zetakines,” comprised of an extracellular domain comprising a soluble receptor ligand linked to a support region capable of tethering the extracellular domain to a cell surface, a transmembrane region and an intracellular signalling domain. Zetakines, when expressed on the surface of T lymphocytes, direct T cell activity to those specific cells expressing a receptor for which the soluble receptor ligand is specific. Zetakine chimeric immunoreceptors represent a novel extension of antibody-based immunoreceptors for redirecting the antigen specificity of T cells, with application to treatment of a variety of cancers, particularly via the autocrin/paracrine cytokine systems utilized by human malignancy. In a preferred embodiment is a glioma-specific immunoreceptor comprising the extracellular targeting domain of the IL-13Rα2-specific IL-13 mutant IL-13(E13Y) linked to the Fc region of IgG, the transmembrane domain of human CD4, and the human CD3 zeta chain. |
FILED | Friday, December 20, 2019 |
APPL NO | 16/723782 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/1774 (20130101) A61K 38/2086 (20130101) Original (OR) Class Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Peptides C07K 14/5437 (20130101) C07K 14/7051 (20130101) C07K 14/7155 (20130101) C07K 14/70514 (20130101) C07K 16/46 (20130101) C07K 19/00 (20130101) C07K 2319/00 (20130101) C07K 2319/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 15/63 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278604 | Kim et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Jaeyun Kim (Gyeonggi-do, South Korea); Weiwei Aileen Li (Norcross, Georgia); David J. Mooney (Sudbury, Massachusetts) |
ABSTRACT | A composition comprising mesoporous silica rods comprising an immune cell recruitment compound and an immune cell activation compound, and optionally comprising an antigen such as a tumor lysate. The composition is used to elicit an immune response to a vaccine antigen. |
FILED | Monday, March 26, 2018 |
APPL NO | 15/935392 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/1611 (20130101) A61K 38/18 (20130101) A61K 38/18 (20130101) A61K 38/193 (20130101) A61K 38/193 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 39/00117 (20180801) A61K 39/00118 (20180801) A61K 39/001102 (20180801) A61K 39/001156 (20180801) A61K 39/001162 (20180801) A61K 39/001171 (20180801) A61K 39/001182 (20180801) A61K 39/001184 (20180801) A61K 39/001186 (20180801) A61K 39/001191 (20180801) A61K 39/001192 (20180801) A61K 2039/80 (20180801) A61K 2039/55522 (20130101) A61K 2039/55555 (20130101) A61K 2039/55561 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278608 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia) |
ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
INVENTOR(S) | Chenming Zhang (Blacksburg, Virginia); Zongmin Zhao (Blacksburg, Virginia); Yun Hu (Blacksburg, Virginia) |
ABSTRACT | Provided herein are nicotine polymer-stabilized nanoparticles, formulations thereof, and vaccines. Also provided herein are methods of treating and/or preventing nicotine addiction in a subject in need thereof. |
FILED | Thursday, January 05, 2017 |
APPL NO | 16/476252 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) A61K 9/5153 (20130101) A61K 39/0013 (20130101) Original (OR) Class A61K 39/385 (20130101) A61K 2039/6081 (20130101) A61K 2039/6093 (20130101) A61K 2039/55505 (20130101) A61K 2039/55544 (20130101) A61K 2039/55555 (20130101) A61K 2039/55561 (20130101) A61K 2039/55572 (20130101) A61K 2039/55588 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/34 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278633 | Yang et al. |
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FUNDED BY |
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APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Aimei Yang (Cambridge, Massachusetts); Demian Park (Cambridge, Massachusetts); Kiryl Piatkevich (Cambridge, Massachusetts); Edward Boyden (Cambridge, Massachusetts) |
ABSTRACT | The invention, in some aspects, relates to dummy-fluorescent (DF) polypeptide molecules and their encoding nucleic acid molecules and use of such molecules in fusion proteins and their encoding nucleic acid molecules. Compositions of the invention may be delivered to cells and subjects and used in methods to modulate electrical activity of cells in which they are expressed, and for treatment of diseases and conditions in subjects. |
FILED | Thursday, July 20, 2017 |
APPL NO | 16/318428 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0045 (20130101) Original (OR) Class Peptides C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278661 | Henderson et al. |
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FUNDED BY |
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APPLICANT(S) | Beta Bionics, Inc. (Concord, Massachusetts) |
ASSIGNEE(S) | BETA BIONICS, INC. (Concord, Massachusetts) |
INVENTOR(S) | David Matthew Henderson (Mission Viejo, California); Todd S. Ray (Spokane Valley, Washington); Michael J. Rosinko (Anaheim, California); Bryan Dale Knodel (Flagstaff, Arizona) |
ABSTRACT | Certain embodiments provide multi-medicament infusion systems for preventing the cross-channeling of medicaments. The system may include one or more of an infusion pump, medicament cartridges, cartridge connectors, a multi-channel fluid conduit, and an infusion set. The infusion pump can have an inductively chargeable battery assembly that can be charged by an inductive charging pad. |
FILED | Tuesday, March 10, 2020 |
APPL NO | 16/814925 |
ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/142 (20130101) A61M 5/162 (20130101) A61M 5/1407 (20130101) Original (OR) Class A61M 5/1723 (20130101) A61M 39/24 (20130101) A61M 2205/8206 (20130101) A61M 2205/8243 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278697 | Galbraith et al. |
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FUNDED BY |
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APPLICANT(S) | Separation Design Group IP Holdings, LLC (Waynesburg, Pennsylvania) |
ASSIGNEE(S) | SEPARATION DESIGN GROUP IP HOLDINGS, LLC (Waynesburg, Pennsylvania) |
INVENTOR(S) | Stephen Douglas Galbraith (Waynesburg, Pennsylvania); Kenneth J. McGowan (Waynesburg, Pennsylvania); Evonne A. Baldauff (Waynesburg, Pennsylvania); Elise N. Depetris (Waynesburg, Pennsylvania); David K. Walker (Waynesburg, Pennsylvania) |
ABSTRACT | Lightweight, portable oxygen concentrators that operate using an ultra rapid, sub one second, adsorption cycle based on advanced molecular sieve materials are disclosed. The amount of sieve material utilized is a fraction of that used in conventional portable devices. This dramatically reduces the volume, weight, and cost of the device. Innovations in valve configuration, moisture control, case and battery design, and replaceable sieve module are described. Patients with breathing disorders and others requiring medical oxygen are provided with a long lasting, low cost alternative to existing portable oxygen supply devices. |
FILED | Friday, November 08, 2019 |
APPL NO | 16/678026 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/0003 (20140204) A61M 16/20 (20130101) A61M 16/0063 (20140204) A61M 16/101 (20140204) Original (OR) Class A61M 16/105 (20130101) A61M 16/107 (20140204) A61M 16/0666 (20130101) A61M 16/0672 (20140204) A61M 16/0875 (20130101) A61M 16/1005 (20140204) A61M 2016/1025 (20130101) A61M 2202/0208 (20130101) A61M 2205/02 (20130101) A61M 2205/42 (20130101) A61M 2205/75 (20130101) A61M 2205/3327 (20130101) A61M 2205/3334 (20130101) A61M 2205/8206 (20130101) Separation B01D 53/02 (20130101) B01D 53/26 (20130101) B01D 53/0415 (20130101) B01D 53/0473 (20130101) B01D 2253/108 (20130101) B01D 2253/304 (20130101) B01D 2256/12 (20130101) B01D 2257/102 (20130101) B01D 2259/4533 (20130101) B01D 2259/4541 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/85938 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279041 | Mahoor et al. |
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FUNDED BY |
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APPLICANT(S) | Dream Face Technologies, LLC (Lone Tree, Colorado) |
ASSIGNEE(S) | Dream Face Technologies, Inc. (Lone Tree, Colorado) |
INVENTOR(S) | Mohammad H. Mahoor (Lone Tree, Colorado); Joshua T. Lane (Englewood, Colorado); Hojjat Abdollahi Pourhaghighi (Denver, Colorado); Eshrat S. Emamian (Lone Tree, Colorado) |
ABSTRACT | A companion robot is disclosed. In some embodiments, the companion robot may include a head having a facemask and a projector configured to project facial images onto the facemask; a facial camera; a microphone configured to receive audio signals from the environment; a speaker configured to output audio signals; and a processor electrically coupled with the projector, the facial camera, the microphone, and the speaker. In some embodiments, the processor may be configured to receive facial images from the facial camera; receive speech input from the microphone; determine an audio output based on the facial images and/or the speech input; determine a facial projection output based the facial images and/or the speech input; output the audio output via the speaker; and project the facial projection output on the facemask via the projector. |
FILED | Friday, October 12, 2018 |
APPL NO | 16/158542 |
ART UNIT | 3666 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1697 (20130101) B25J 11/001 (20130101) B25J 11/003 (20130101) B25J 11/0015 (20130101) Original (OR) Class B25J 13/003 (20130101) Electric Digital Data Processing G06F 3/16 (20130101) G06F 3/0481 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00302 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 3/002 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 25/63 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279698 | Babich et al. |
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FUNDED BY |
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APPLICANT(S) | Cornell University (Ithaca, New York) |
ASSIGNEE(S) | Cornell University (Ithaca, New York) |
INVENTOR(S) | John W. Babich (New York, New York); Justin Wilson (Ithaca, New York); Nikki Thiele (Brooktondale, New York); James Kelly (New York, New York); Shashikanth Ponnala (Ithaca, New York) |
ABSTRACT | The present technology provides compounds as well as compositions including such compounds useful in targeted radiotherapy of cancer and/or mammalian tissue overexpressing prostate specific membrane antigen (“PSMA”) where the compounds are represented by the following: or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, wherein M1 is independently at each occurrence an alpha-emitting radionuclide. Equivalents of such compounds are also disclosed. |
FILED | Wednesday, November 20, 2019 |
APPL NO | 16/689856 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 51/0463 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/002 (20130101) Heterocyclic Compounds C07D 413/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279706 | Mulcahy et al. |
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FUNDED BY |
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APPLICANT(S) | SITEONE THERAPEUTICS, INC. (Bozeman, Montana); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
ASSIGNEE(S) | SITEONE THERAPEUTICS, INC. (Bozeman, Montana); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
INVENTOR(S) | John Mulcahy (Bozeman, Montana); Hassan Pajouhesh (Bozeman, Montana); George Miljanich (Bozeman, Montana); Anton Delwig (Bozeman, Montana); Jacob Beckley (Bozeman, Montana); Grant Masaaki Shibuya (Bozeman, Montana); Justin Du Bois (Stanford, California) |
ABSTRACT | Provided herein are compounds, pharmaceutical compositions comprising the compounds, methods of preparing the compounds, and methods of using the compounds and compositions in treating conditions associated with voltage-gated sodium channel function where the compounds are 11,13-modified saxitoxins according to Formula (I): where R1, X1, and X2 are as described herein. |
FILED | Thursday, March 29, 2018 |
APPL NO | 16/499201 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) Heterocyclic Compounds C07D 487/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279708 | Porco, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
INVENTOR(S) | John A. Porco, Jr. (Brookline, Massachusetts); Wenhan Zhang (Allston, Massachusetts); Gerard Pelletier (Quebec, Canada); Jennifer Chu (Dorchester, Massachusetts) |
ABSTRACT | Herein are described the preparation of a series of synthetic rocaglates, amidino- and amino-rocaglates, which display inhibition of protein translation and tumor cell proliferation (in vitro and in vivo). The methods described herein allow the preparation of libraries of modified rocaglates. This chemical modification of the rocaglate scaffold changes the C8b-hydroxyl of the natural product series to a more optimal hydrogen bond donor/acceptor. |
FILED | Thursday, June 11, 2020 |
APPL NO | 16/898959 |
ART UNIT | 1699 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 491/048 (20130101) Original (OR) Class C07D 491/147 (20130101) C07D 513/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279728 | Almo et al. |
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FUNDED BY |
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APPLICANT(S) | Albert Einstein College of Medicine (Bronx, New York); The Penn State Research Foundation (University Park, Pennsylvania) |
ASSIGNEE(S) | Albert Einstein College of Medicine (Bronx, New York); The Penn State Research Foundation (University Park, Pennsylvania) |
INVENTOR(S) | Steven C. Almo (Pelham, New York); Tyler Grove (Bronx, New York); Anthony Gizzi (Baltimore, Maryland); Craig E. Cameron (State College, Pennsylvania); James J. Arnold (State College, Pennsylvania) |
ABSTRACT | Compounds and methods for treating viral infections and reducing viral multiplication, including flaviviruses. Provided is a derivative of a compound or a pharmaceutical salt thereof, wherein the compound comprises a 3′,4-didehydroribose. |
FILED | Tuesday, August 21, 2018 |
APPL NO | 16/640845 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/06 (20130101) C07H 19/10 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279733 | Cooper et al. |
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FUNDED BY |
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APPLICANT(S) | THE UNIVERSITY OF QUEENSLAND (St Lucia, Australia) |
ASSIGNEE(S) | THE UNIVERSITY OF QUEENSLAND (St Lucia, Australia) |
INVENTOR(S) | Matthew Cooper (St Lucia, Australia); Mark Blaskovich (St Lucia, Australia); Alejandra Gallardo-Godoy (St Lucia, Australia); Karl Hansford (St Lucia, Australia); Alysha Elliott (St Lucia, Australia); Craig Muldoon (Springwood, Australia); Bernd Becker (New Farm, Australia) |
ABSTRACT | There is provided a range of novel compounds. These novel compounds may demonstrate abroad spectrum antibacterial and antifungal activity. These compounds may be active against the emerging polymyxin resistant bacteria. These compounds may also be useful when used in conjunction with other pharmaceutically active agents. |
FILED | Friday, November 02, 2018 |
APPL NO | 16/761067 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/12 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 7/56 (20130101) C07K 7/62 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279736 | Ly et al. |
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FUNDED BY |
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APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Danith H. Ly (Pittsburgh, Pennsylvania); Srinivas Rapireddy (Pittsburgh, Pennsylvania); Bichismita Sahu (Pittsburgh, Pennsylvania) |
ABSTRACT | The present invention relates to γ-PNA monomers according to Formula I where substituent groups R1, R2, R3, R4, R5, R6, B and P are defined as set forth in the specification. The invention also provides methodology for synthesizing compounds according to Formula I and methodology for synthesizing PNA oligomers that incorporate one or more Formula I monomers. |
FILED | Wednesday, August 26, 2020 |
APPL NO | 17/003131 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/60 (20170801) Acyclic or Carbocyclic Compounds C07C 229/12 (20130101) C07C 271/20 (20130101) Heterocyclic Compounds C07D 239/47 (20130101) C07D 239/54 (20130101) C07D 473/18 (20130101) C07D 473/34 (20130101) Peptides C07K 1/04 (20130101) C07K 1/08 (20130101) C07K 14/003 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279738 | Simon et al. |
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FUNDED BY |
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APPLICANT(S) | MOREHOUSE SCHOOL OF MEDICINE (Atlanta, Georgia) |
ASSIGNEE(S) | MOREHOUSE SCHOOL OF MEDICINE (Atlanta, Georgia) |
INVENTOR(S) | Roger P. Simon (Atlanta, Georgia); Zhigang Xiong (Atlanta, Georgia) |
ABSTRACT | A system, including methods and compositions, for treatment of ischemia. |
FILED | Wednesday, June 17, 2020 |
APPL NO | 16/946333 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/439 (20130101) A61K 31/498 (20130101) A61K 31/4418 (20130101) A61K 31/4965 (20130101) A61K 38/16 (20130101) A61K 38/17 (20130101) A61K 38/1767 (20130101) A61K 45/06 (20130101) Peptides C07K 14/43518 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279752 | Williams et al. |
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FUNDED BY |
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APPLICANT(S) | City of Hope (Duarte, California); Thomas Jefferson University (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | CITY OF HOPE (Duarte, California); THOMAS JEFFERSON UNIVERSITY (Philadelphia, Pennsylvania) |
INVENTOR(S) | John C. Williams (Monrovia, California); Ulrich Rodeck (Philadelphia, Pennsylvania); Kurt Jenkins (Duarte, California) |
ABSTRACT | Provided herein are recombinant masking proteins and recombinant ligand proteins useful in treating cancer, neurodegenerative disease, and cardiovascular disease. The recombinant masking proteins provided herein may, inter alia, be used as non-covalent masks of antagonists of, for example, cellular growth factors (e.g., TNF) or cell surface proteins (e.g., CTLA-4). |
FILED | Tuesday, September 03, 2019 |
APPL NO | 16/559561 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 14/47 (20130101) C07K 14/71 (20130101) C07K 14/82 (20130101) Original (OR) Class C07K 14/70521 (20130101) C07K 14/70596 (20130101) C07K 16/2818 (20130101) C07K 2317/35 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) C07K 2318/20 (20130101) C07K 2319/30 (20130101) C07K 2319/50 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/6491 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279754 | Pahan |
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FUNDED BY |
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APPLICANT(S) | RUSH UNIVERSITY MEDICAL CENTER (Chicago, Illinois) |
ASSIGNEE(S) | RUSH UNIVERSITY MEDICAL CENTER (Chicago, Illinois) |
INVENTOR(S) | Kalipada Pahan (Skokie, Illinois) |
ABSTRACT | One aspect of the invention provides a method for treating a cancer including administering to a subject in need of such treatment a composition including a therapeutically effective amount of an antibody directed against p40 monomer or an immunologically active fragment thereof. In various embodiments, the antibody is a polyclonal, monoclonal, human, humanized, and chimeric antibody; a single chain antibody or an epitope-binding antibody fragment. In other embodiments, the cancer is, for example, prostate cancer, breast cancer or liver cancer. |
FILED | Friday, March 04, 2016 |
APPL NO | 15/551710 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/395 (20130101) Peptides C07K 16/244 (20130101) Original (OR) Class C07K 16/3069 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279763 | Chen |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Lu Chen (Oakland, California) |
ABSTRACT | In certain embodiments, the present invention provides methods of suppressing valvulogenesis (VG) in a lymphatic vessel in an inflamed or transplanted tissue or organ in a mammal in need thereof comprising administering an effective amount of an anti-integrin alpha 9 (Itga-9) therapeutic agent to the mammal, and optionally by administering anti-VEGFR-3 agent. |
FILED | Thursday, October 26, 2017 |
APPL NO | 16/344741 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0048 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) Peptides C07K 16/2839 (20130101) Original (OR) Class C07K 2317/54 (20130101) C07K 2317/56 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279765 | Fukumura et al. |
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FUNDED BY |
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APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Dai Fukumura (Newton, Massachusetts); Keehoon Jung (Boston, Massachusetts); Rakesh K. Jain (Wellesley, Massachusetts) |
ABSTRACT | Agents that inhibit CX3CL1 in endothelial cells to reduce or inhibit immunosuppression mechanisms that are co-opted by cancer cells to evade host immune system, and that reduce immunosuppression in context of therapies that target VEGF-dependent signaling, and methods of use thereof. |
FILED | Monday, July 09, 2018 |
APPL NO | 16/628941 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/5123 (20130101) A61K 31/713 (20130101) A61K 47/62 (20170801) A61K 47/6935 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/24 (20130101) C07K 16/2866 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1136 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279914 | Andersen et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Jimena Andersen (Palo Alto, California); Fikri Birey (Palo Alto, California); Sergiu P. Pasca (Palo Alto, California) |
ABSTRACT | Human pluripotent stem cells are differentiated in vitro into forebrain subdomain structures, which are then fused to generate an integrated system for use in analysis, screening programs, and the like. |
FILED | Wednesday, May 27, 2020 |
APPL NO | 16/884980 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/10 (20130101) C12N 5/0012 (20130101) C12N 5/0062 (20130101) C12N 5/0619 (20130101) C12N 5/0622 (20130101) Original (OR) Class C12N 5/0623 (20130101) C12N 5/0696 (20130101) C12N 2501/01 (20130101) C12N 2501/11 (20130101) C12N 2501/13 (20130101) C12N 2501/15 (20130101) C12N 2501/115 (20130101) C12N 2501/155 (20130101) C12N 2501/385 (20130101) C12N 2506/45 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5058 (20130101) G01N 2333/70571 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279915 | Brown |
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FUNDED BY |
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APPLICANT(S) | Maine Medical Center Research Institute (Scarborough, Maine) |
ASSIGNEE(S) | Maine Medical Center Research Institute (Scarborough, Maine) |
INVENTOR(S) | Aaron C. Brown (Portland, Maine) |
ABSTRACT | Provided herein are, inter alia, methods, compositions, and kits for producing adipocyte populations such as beige adipocyte populations. Also included are methods and compositions for increasing the level of adipocyte populations (e.g., beige adipocyte populations) in a subject, as well as methods and compositions for treating subjects who are overweight, obese, or who have diabetes. |
FILED | Friday, January 11, 2019 |
APPL NO | 16/245298 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/35 (20130101) A61K 38/2026 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) A61P 3/06 (20180101) A61P 3/10 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0653 (20130101) Original (OR) Class C12N 2501/999 (20130101) C12N 2501/2304 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279922 | Ponnapakkam et al. |
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FUNDED BY |
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APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas); The Kitasato Institute (Tokyo, Japan); MONTEFIORE MEDICAL CENTER (New York, New York); NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY (Kagawa, Japan) |
ASSIGNEE(S) | The Board of Trustees of the University of Arkansas (Little Rock, Arkansas); The Kitasato Institute (Tokyo, Japan); Montefiore Medical Center (New York, New York); National University Corporation Kagawa University (Kagawa, Japan) |
INVENTOR(S) | Tulasi Ponnapakkam (New York, New York); Sagaya Theresa Leena Philominathan (Cheshire, Connecticut); Joshua Sakon (Fayetteville, Arkansas); Ranjitha Katikaneni (New York, New York); Takaki Koide (Tokyo, Japan); Osamu Matsushita (Kanagawa, Japan); Robert C. Gensure (New York, New York); Nozomu Nishi (Kagawa, Japan) |
ABSTRACT | Methods of delivering therapeutic agents by administering compositions including a bacterial collagen-binding polypeptide segment linked to the therapeutic agent to subjects in need of treatment with the therapeutic agent are provided. In these methods, the therapeutic agent is not a PTH/PTHrP receptor agonist or antagonist, basic fibroblast growth factor (bFGF) or epidermal growth factor (EGF). The bacterial collagen-binding polypeptide segment delivers the agent to sites of partially untwisted or under-twisted collagen. Methods of treating collagenopathies using a composition including a collagen-binding polypeptide and a PTH/PTHrP receptor agonist are also provided. In addition, methods of treating hyperparathyroidism, and hair loss using compositions comprising a collagen binding polypeptide and a PTH/PTHrP receptor agonist are provided. Finally, methods of reducing hair regrowth by administering a composition including a collagen binding polypeptide and a PTH/PTHrP receptor antagonist are provided. |
FILED | Friday, February 22, 2019 |
APPL NO | 16/283468 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/64 (20130101) A61K 8/65 (20130101) A61K 8/66 (20130101) A61K 8/4913 (20130101) A61K 38/00 (20130101) A61K 38/18 (20130101) A61K 38/27 (20130101) A61K 38/29 (20130101) A61K 38/30 (20130101) A61K 38/179 (20130101) A61K 38/193 (20130101) A61K 38/1808 (20130101) A61K 38/1825 (20130101) A61K 38/1841 (20130101) A61K 38/1858 (20130101) A61K 38/1866 (20130101) A61K 38/1875 (20130101) A61K 39/44 (20130101) A61K 39/3955 (20130101) A61K 47/64 (20170801) A61K 2039/505 (20130101) A61K 2039/6031 (20130101) A61K 2800/57 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 7/00 (20130101) A61Q 7/02 (20130101) Peptides C07K 14/49 (20130101) C07K 14/50 (20130101) C07K 14/51 (20130101) C07K 14/61 (20130101) C07K 14/71 (20130101) C07K 14/475 (20130101) C07K 14/485 (20130101) C07K 14/495 (20130101) C07K 14/535 (20130101) C07K 16/18 (20130101) C07K 2319/31 (20130101) C07K 2319/70 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) Original (OR) Class Enzymes C12Y 304/24003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279926 | Lane et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Andrew B. Lane (Berkeley, California); Rebecca Heald (Berkeley, California) |
ABSTRACT | The present disclosure provides methods, kits, and compositions for generating DNA molecules encoding CRISPR/Cas guide RNAs (e.g., Cas9 single guide RNAs or Cas9 targeter RNAs). A library of such DNA molecules can be generated from any DNA source. The methods include a step of contacting target DNA with one or more DNA endonucleases that specifically bind to and cleave within a recognition sequence that includes a PAM sequence, to generate a plurality of cleavage fragments, to which a DNA adapter can be attached. A distal-cleaving DNA endonuclease can be used that specifically binds to a recognition sequence in the DNA adapter and cleaves at a site within the attached DNA cleavage fragments to generate a library of CRISPR/Cas guide sequences. After removal of all or a portion of the DNA adapter, a constant region of a guide RNA can be attached to generate DNA molecules encoding CRISPR/Cas guide RNAs. |
FILED | Thursday, June 02, 2016 |
APPL NO | 15/765420 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/09 (20130101) C12N 15/52 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/1093 (20130101) Original (OR) Class C12N 15/1093 (20130101) C12N 2310/20 (20170501) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6855 (20130101) C12Q 2521/301 (20130101) C12Q 2521/301 (20130101) C12Q 2521/313 (20130101) C12Q 2521/313 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/06 (20130101) C40B 50/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279930 | Khvorova et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
ASSIGNEE(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
INVENTOR(S) | Anastasia Khvorova (Westborough, Massachusetts); Julia Alterman (Worcester, Massachusetts); Sarah Davis (Boston, Massachusetts); Anton Turanov (Boston, Massachusetts) |
ABSTRACT | Novel oligonucleotides that are fully chemically stabilized are provided. Methods of using oligonucleotides that are fully chemically stabilized are also provided. |
FILED | Friday, August 23, 2019 |
APPL NO | 16/550076 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/52 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279959 | Boville et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Christina E. Boville (Pasadena, California); Sabine Brinkmann-Chen (Glendale, California); Andrew R. Buller (Pasadena, California); David K. Romney (Pasadena, California); Christopher K. Prier (Brooklyn, New York); Philipp Koch (Basel, Switzerland); Remkes A. Scheele (Nijeveen, Netherlands) |
ABSTRACT | The present disclosure provides methods for preparing β-substituted tryptophan compounds. The methods include: combining i) an unsubstituted indole or a substituted indole, ii) a β-substituted serine, and iii) a tryptophan synthase β-subunit (i.e., a TrpB); and maintaining the resulting mixture under conditions sufficient to form the β-substituted tryptophan. The TrpB contains at least one amino acid mutation which promotes formation of an amino-acrylate intermediate. New TrpB variants and new β-substituted tryptophan analogs are also described. |
FILED | Monday, March 16, 2020 |
APPL NO | 16/820538 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) C12N 15/8254 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 13/04 (20130101) C12P 13/005 (20130101) C12P 13/06 (20130101) C12P 13/227 (20130101) Original (OR) Class Enzymes C12Y 402/0102 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279974 | Lieberman-Aiden et al. |
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FUNDED BY |
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APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
INVENTOR(S) | Erez Lieberman-Aiden (Houston, Texas); Suhas Rao (Medfield, Massachusetts); Elena Stamenova (Reading, Massachusetts); Olga Dudchenko (Houston, Texas); Eric Lander (Cambridge, Massachusetts) |
ABSTRACT | Disclosed is an in situ method for detecting spatial proximity relationships between nucleic acid sequences, such as DNA, in a cell. The method includes: providing a sample of one or more cells comprising nucleic acids; fragmenting the nucleic acids present in the cells that leaves 5′ overhanging ends; filling in the overhanging ends with at least one labeled nucleotide; joining the filled in end of the fragmented nucleic acids that are in close physical proximity to create one or more end joined nucleic acid fragments having a junction; isolating the one or more end joined nucleic acid fragments using the labeled nucleotide; and determining the sequence at the junction of the one or more end joined nucleic acid fragments. |
FILED | Tuesday, December 01, 2015 |
APPL NO | 15/532353 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2521/501 (20130101) C12Q 2521/501 (20130101) C12Q 2521/501 (20130101) C12Q 2525/117 (20130101) C12Q 2525/117 (20130101) C12Q 2525/117 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2563/131 (20130101) C12Q 2563/131 (20130101) C12Q 2563/131 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 20/00 (20130101) C40B 30/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279980 | Delker et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
ASSIGNEE(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
INVENTOR(S) | Don Delker (West Valley City, Utah); Priyanka Kanth (Salt Lake City, Utah) |
ABSTRACT | Disclosed herein are methods for identifying a genetic susceptibility to colon cancer in as subject, the method comprising determining the mRNA expression level of one or more of FSCN1, ZIC2, ZIC5, CRYBA2, MUC6, TRNP1 and SEMG1 in a colon tissue sample in the subject, where a ratio of the sample expression level of one or more genes in the panel to a reference expression level of one or more genes in the panel indicates cancer or and increased susceptibility of cancer. Disclosed herein are diagnostic devices comprising one or more biomarkers, wherein the biomarkers are FSCN1, ZIC2, ZIC5, CRYBA2, MUC6, TRNP1 and SEMG1; and a gene expression panel consisting of primers or probes for detecting FSCN1, ZIC2, ZIC5, CRYBA2, MUC6, TRNP1 and SEMG1 in a sample, and methods for assessing risk of developing colon cancer in a subject. |
FILED | Tuesday, January 24, 2017 |
APPL NO | 16/072162 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6806 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/154 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280708 | Fiorelli et al. |
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FUNDED BY |
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APPLICANT(S) | DIGNITY HEALTH (Phoenix, Arizona) |
ASSIGNEE(S) | Dignity Health (Phoenix, Arizona) |
INVENTOR(S) | Roberto Fiorelli (Scottsdale, Arizona); Gurpaul Singh Sidhu (Chandler, Arizona) |
ABSTRACT | Provided herein are systems, devices, and methods for improved treatment of tissue, such as brain tissue. The improved treatment described herein can result in improved tissue penetration of various compounds and chemicals, such as stains and immunohistochemistry reagents. For example, provided herein is a pressurizing device that may include a chamber body having an opening in one of a top and a sidewall of the body, and may also include a chamber lid covering the opening and releasably coupled to the chamber body proximate the opening. The chamber lid and chamber body form an air-tight cavity. The pressurizing device may also have an inlet passing through one of the chamber body and the chamber lid and into the air-tight cavity. The device may also include a retainer coupled inside the air-tight cavity and configured to releasably couple to at least one tissue sample receptacles. |
FILED | Monday, April 27, 2020 |
APPL NO | 16/859981 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 1/31 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280710 | Hildebrand et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | David Grant Colburn Hildebrand (Cambridge, Massachusetts); Brett Jesse Graham (Waltham, Massachusetts); Wei-Chung Allen Lee (Cambridge, Massachusetts) |
ABSTRACT | A tape for collecting tissue samples in a manner compatible with imaging in a transmission electron microscopy (TEM) system, includes a tape substrate having two side walls forming a trough. The trough is defined by a bottom surface of the tape substrate and internal surfaces of the side walls, with an open side therebetween. A support film is attached to a top surface of the tape substrate, and a plurality of apertures is spaced at predetermined locations along the length of the tape substrate, each aperture being covered by the support film. The tape includes a stacked configuration in which the tape substrate is wound in layers, the bottom surfaces of the side walls in one layer being in contact with the support film in an immediately adjacent layer. The apertures in the second layer are aligned within the trough of the first layer, between the side walls. |
FILED | Tuesday, April 18, 2017 |
APPL NO | 16/095568 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/36 (20130101) Original (OR) Class G01N 35/00009 (20130101) G01N 2001/362 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/20 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280732 | Perera et al. |
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FUNDED BY |
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APPLICANT(S) | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Atlanta, Georgia) |
ASSIGNEE(S) | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Atlanta, Georgia) |
INVENTOR(S) | A. G. Unil Perera (Mableton, Georgia); Hemendra Mani Ghimire (Decatur, Georgia) |
ABSTRACT | The present disclosure relates to methods for the detection of melanoma and non-Hodgkin's lymphoma using attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy. Further disclosed are methods for treating melanoma and non-Hodgkin's lymphoma, based on differences in infrared absorbance. |
FILED | Tuesday, August 20, 2019 |
APPL NO | 16/545409 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0059 (20130101) A61B 5/444 (20130101) A61B 5/7257 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/35 (20130101) G01N 21/552 (20130101) Original (OR) Class G01N 2021/3595 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280782 | Miller et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF ROCHESTER (Rochester, New York); ADARZA BIOSYSTEMS, INC. (West Henrietta, New York) |
ASSIGNEE(S) | UNIVERSITY OF ROCHESTER (Rochester, New York) |
INVENTOR(S) | Benjamin L. Miller (Penfield, New York); Mark A. Lifson (Rochester, New York); Jared A. Carter (West Henrietta, New York) |
ABSTRACT | Disclosed is a sensor chip for detecting a target molecule in a sample. The sensor chip includes a substrate having a surface and a layer of hydrogel particles immobilized on the substrate surface at two or more locations on the surface, wherein the hydrogel particles at a first location comprise a plurality of first probe molecules bound to the particles and the hydrogel particles at a second location comprise a plurality of second probe molecules bound to the particles. Systems that include the sensor chip, as well as methods of preparing and using the sensor chip, are also disclosed. |
FILED | Monday, February 08, 2016 |
APPL NO | 15/546737 |
ART UNIT | 1699 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/545 (20130101) G01N 33/5432 (20130101) G01N 33/54313 (20130101) G01N 33/54366 (20130101) Original (OR) Class G01N 33/54373 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280787 | List |
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FUNDED BY |
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APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
INVENTOR(S) | Alan F. List (Tampa, Florida) |
ABSTRACT | Disclosed are methods for diagnosing a myelodysplastic syndrome (MDS) in a subject. In some embodiments, the method involves assaying a sample from the subject to detect inflammasome activation, wherein an increase in inflammasome activation in the sample compared to a control is an indication of MDS in the subject. The disclosed methods can further involve treating the subject for MDS if an increase in inflammasome activation is detected. |
FILED | Monday, November 11, 2019 |
APPL NO | 16/679684 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 14/545 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/06 (20130101) C12Q 1/68 (20130101) C12Q 1/6809 (20130101) C12Q 1/6886 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/68 (20130101) G01N 33/564 (20130101) Original (OR) Class G01N 33/573 (20130101) G01N 33/574 (20130101) G01N 33/6893 (20130101) G01N 33/57426 (20130101) G01N 33/57484 (20130101) G01N 2333/964 (20130101) G01N 2333/96466 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280797 | Mapstone et al. |
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FUNDED BY |
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APPLICANT(S) | Georgetown University (Washington, District of Columbia); University of Rochester (Rochester, New York) |
ASSIGNEE(S) | Georgetown University (Washington, District of Columbia); University of Rochester (Rochester, New York) |
INVENTOR(S) | Mark E. Mapstone (Irvine, California); Howard J. Federoff (Irvine, California); Massimo S. Fiandaca (Irvine, California); Amrita K. Cheema (Potomac, Maryland) |
ABSTRACT | The present invention relates to methods of determining if a subject has a decreased risk of suffering from future memory impairment. The methods comprise analyzing at least one plasma sample from the subject to determine a value of the subject's metabolite profile and comparing the value of the subject's metabolite profile with the value of a normal metabolite profile. A change in the value of the subject's metabolite profile, over normal values is indicative that the subject has a decreased risk of suffering from future memory impairment compared to a normal individual. |
FILED | Friday, February 02, 2018 |
APPL NO | 16/483260 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) Original (OR) Class G01N 2560/00 (20130101) G01N 2800/50 (20130101) G01N 2800/52 (20130101) G01N 2800/2814 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280866 | Pan et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Jullie W. Pan (Wexford, Pennsylvania); Chan-Hong Moon (Pittsburgh, Pennsylvania); Hoby Hetherington (Wexford, Pennsylvania) |
ABSTRACT | A magnetic resonance imaging method includes performing an inversion pulse sequence using an MRI system, the inversion pulse sequence producing an inversion recovery period, and during the inversion recovery period: (i) performing a longitudinal T2 encoding pulse sequence using the MRI system; (ii) acquiring a post longitudinal T2 encoding pulse sequence image signal block immediately following the longitudinal T2 encoding pulse sequence using the MRI system; and (iii) acquiring an additional image signal block either before the longitudinal T2 encoding pulse sequence or following the acquiring of the post longitudinal T2 encoding pulse sequence image signal block using the MRI system. The method further include generating calculated image data based on at least the post longitudinal T2 encoding pulse sequence image signal block using a self-correcting normalization image combination scheme. |
FILED | Thursday, June 13, 2019 |
APPL NO | 15/734337 |
ART UNIT | 2852 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/4822 (20130101) G01R 33/5602 (20130101) Original (OR) Class G01R 33/5616 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11283096 | Kulkarni et al. |
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FUNDED BY |
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APPLICANT(S) | Arborsense, Inc. (Ann Arbor, Michigan) |
ASSIGNEE(S) | Arborsense, Inc. (Ann Arbor, Michigan) |
INVENTOR(S) | Girish Kulkarni (Ann Arbor, Michigan); Donald Kahaian (Farmington, Michigan) |
ABSTRACT | A method for fabricating an electrochemical sensor material includes positioning sheets of molded graphene nanoplatelets on each side of a proton exchange membrane and integrating graphene nanoplatelets into regions of the proton exchange membrane adjacent its surfaces by applying heat to increase the temperature of the proton exchange membrane to its glass transition temperature and applying compressive pressure to press a portion of each sheet of molded graphene nanoplatelets into the softened polymeric material of the proton exchange membrane. Following application of heat and pressure, the proton exchange membrane is cooled and excess graphene material is exfoliated. Electrochemical sensor components are cut from the material and electrochemical devices and systems are constructed therefrom. |
FILED | Wednesday, May 22, 2019 |
APPL NO | 16/419290 |
ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 65/02 (20130101) B29C 66/7444 (20130101) B29C 66/8122 (20130101) B29C 66/73141 (20130101) B29C 66/73183 (20130101) B29C 66/83221 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 2255/20 (20130101) B32B 2264/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/333 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/102 (20130101) Original (OR) Class H01M 8/1048 (20130101) H01M 8/1069 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 11278226 | Heydari et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California); University of Southern California (Los Angeles, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
INVENTOR(S) | Payam Heydari (Irvine, California); Zoran Nenadic (Irvine, California); An Do (Orange, California); Charles Liu (Los Angeles, California) |
ABSTRACT | A fully-implantable brain-computer interface cyber-physical system capable of acquiring and analyzing electrocorticogram (“ECoG”) signals, recorded directly from the subdural space of the brain, to enable direct brain control of a prosthetic (e.g., a robotic gait exoskeleton or a functional electrical stimulation (“FES”) system) is disclosed. The present system comprises a plurality of electrodes, for acquiring the ECoG signals, and a digital signal processor (“DSP”) for deriving a plurality of real-time commands from the ECoG signals. These real-time commands may then be wirelessly transmitted to the prosthetic for execution. Further, to avoid wireless data transmission of the ECoG signals from the plurality of electrodes to the DSP, which would expose the brain, skull, and scalp tissue to potentially harmful radio frequencies, a subcutaneous tunneling cable operatively couples the plurality of electrodes and the DSP. |
FILED | Friday, April 05, 2019 |
APPL NO | 16/376831 |
ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/24 (20210101) Original (OR) Class A61B 5/30 (20210101) A61B 5/369 (20210101) A61B 5/4851 (20130101) A61B 5/6868 (20130101) A61B 5/7225 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/72 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 2201/165 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0534 (20130101) Electric Digital Data Processing G06F 3/00 (20130101) G06F 3/01 (20130101) G06F 3/015 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278633 | Yang et al. |
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FUNDED BY |
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APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Aimei Yang (Cambridge, Massachusetts); Demian Park (Cambridge, Massachusetts); Kiryl Piatkevich (Cambridge, Massachusetts); Edward Boyden (Cambridge, Massachusetts) |
ABSTRACT | The invention, in some aspects, relates to dummy-fluorescent (DF) polypeptide molecules and their encoding nucleic acid molecules and use of such molecules in fusion proteins and their encoding nucleic acid molecules. Compositions of the invention may be delivered to cells and subjects and used in methods to modulate electrical activity of cells in which they are expressed, and for treatment of diseases and conditions in subjects. |
FILED | Thursday, July 20, 2017 |
APPL NO | 16/318428 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0045 (20130101) Original (OR) Class Peptides C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278697 | Galbraith et al. |
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FUNDED BY |
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APPLICANT(S) | Separation Design Group IP Holdings, LLC (Waynesburg, Pennsylvania) |
ASSIGNEE(S) | SEPARATION DESIGN GROUP IP HOLDINGS, LLC (Waynesburg, Pennsylvania) |
INVENTOR(S) | Stephen Douglas Galbraith (Waynesburg, Pennsylvania); Kenneth J. McGowan (Waynesburg, Pennsylvania); Evonne A. Baldauff (Waynesburg, Pennsylvania); Elise N. Depetris (Waynesburg, Pennsylvania); David K. Walker (Waynesburg, Pennsylvania) |
ABSTRACT | Lightweight, portable oxygen concentrators that operate using an ultra rapid, sub one second, adsorption cycle based on advanced molecular sieve materials are disclosed. The amount of sieve material utilized is a fraction of that used in conventional portable devices. This dramatically reduces the volume, weight, and cost of the device. Innovations in valve configuration, moisture control, case and battery design, and replaceable sieve module are described. Patients with breathing disorders and others requiring medical oxygen are provided with a long lasting, low cost alternative to existing portable oxygen supply devices. |
FILED | Friday, November 08, 2019 |
APPL NO | 16/678026 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/0003 (20140204) A61M 16/20 (20130101) A61M 16/0063 (20140204) A61M 16/101 (20140204) Original (OR) Class A61M 16/105 (20130101) A61M 16/107 (20140204) A61M 16/0666 (20130101) A61M 16/0672 (20140204) A61M 16/0875 (20130101) A61M 16/1005 (20140204) A61M 2016/1025 (20130101) A61M 2202/0208 (20130101) A61M 2205/02 (20130101) A61M 2205/42 (20130101) A61M 2205/75 (20130101) A61M 2205/3327 (20130101) A61M 2205/3334 (20130101) A61M 2205/8206 (20130101) Separation B01D 53/02 (20130101) B01D 53/26 (20130101) B01D 53/0415 (20130101) B01D 53/0473 (20130101) B01D 2253/108 (20130101) B01D 2253/304 (20130101) B01D 2256/12 (20130101) B01D 2257/102 (20130101) B01D 2259/4533 (20130101) B01D 2259/4541 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/85938 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278881 | Di Carlo et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Dino Di Carlo (Los Angeles, California); Chueh-Yu Wu (Los Angeles, California); Ghulam Destgeer (Los Angeles, California); Mengxing Ouyang (Culver City, California) |
ABSTRACT | Sub-millimeter scale three-dimensional (3D) structures are disclosed with customizable chemical properties and/or functionality. The 3D structures are referred to as drop-carrier particles. The drop-carrier particles allow the selective association of one solution (i.e., a dispersed phased) with an interior portion of each of the drop-carrier particles, while a second non-miscible solution (i.e., a continuous phase) associates with an exterior portion of each of the drop-carrier particles due to the specific chemical and/or physical properties of the interior and exterior regions of the drop-carrier particles. The combined drop-carrier particle with the dispersed phase contained therein is referred to as a particle-drop. The selective association results in compartmentalization of the dispersed phase solution into sub-microliter-sized volumes contained in the drop-carrier particles. The compartmentalized volumes can be used for single-molecule assays as well as single-cell, and other single-entity assays. |
FILED | Wednesday, July 28, 2021 |
APPL NO | 17/387990 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0262 (20130101) Original (OR) Class B01L 3/502715 (20130101) B01L 3/502784 (20130101) B01L 2300/021 (20130101) B01L 2300/0816 (20130101) B01L 2300/0877 (20130101) B01L 2300/0896 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/04 (20130101) C12N 5/0625 (20130101) C12N 5/0636 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 2535/122 (20130101) C12Q 2563/159 (20130101) C12Q 2563/179 (20130101) C12Q 2565/629 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5432 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279022 | Guerin et al. |
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FUNDED BY |
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APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Kelleher Guerin (Baltimore, Maryland); Gregory D. Hager (Baltimore, Maryland) |
ABSTRACT | System and methods to create an immersive virtual environment using a virtual reality system that receives parameters corresponding to a real-world robot. The real-world robot may be simulated to create a virtual robot based on the received parameters. The immersive virtual environment may be transmitted to a user. The user may supply input and interact with the virtual robot. Feedback such as the current state of the virtual robot or the real-world robot may be provided to the user. The user may train the virtual robot. The real-world robot may be programmed based on the virtual robot training. |
FILED | Thursday, June 06, 2019 |
APPL NO | 16/433162 |
ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1605 (20130101) Original (OR) Class B25J 9/1671 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/40131 (20130101) G05B 2219/45097 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/05 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279041 | Mahoor et al. |
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FUNDED BY |
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APPLICANT(S) | Dream Face Technologies, LLC (Lone Tree, Colorado) |
ASSIGNEE(S) | Dream Face Technologies, Inc. (Lone Tree, Colorado) |
INVENTOR(S) | Mohammad H. Mahoor (Lone Tree, Colorado); Joshua T. Lane (Englewood, Colorado); Hojjat Abdollahi Pourhaghighi (Denver, Colorado); Eshrat S. Emamian (Lone Tree, Colorado) |
ABSTRACT | A companion robot is disclosed. In some embodiments, the companion robot may include a head having a facemask and a projector configured to project facial images onto the facemask; a facial camera; a microphone configured to receive audio signals from the environment; a speaker configured to output audio signals; and a processor electrically coupled with the projector, the facial camera, the microphone, and the speaker. In some embodiments, the processor may be configured to receive facial images from the facial camera; receive speech input from the microphone; determine an audio output based on the facial images and/or the speech input; determine a facial projection output based the facial images and/or the speech input; output the audio output via the speaker; and project the facial projection output on the facemask via the projector. |
FILED | Friday, October 12, 2018 |
APPL NO | 16/158542 |
ART UNIT | 3666 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1697 (20130101) B25J 11/001 (20130101) B25J 11/003 (20130101) B25J 11/0015 (20130101) Original (OR) Class B25J 13/003 (20130101) Electric Digital Data Processing G06F 3/16 (20130101) G06F 3/0481 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00302 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 3/002 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 25/63 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279626 | Pellenbarg et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Trustees of the California State University (Long Beach, California) |
ASSIGNEE(S) | Board of Trustees of the California State University (Long Beach, California) |
INVENTOR(S) | Robert E. Pellenbarg (San Bernardino, California); Kimberley R. Cousins (San Bernardino, California) |
ABSTRACT | Provided is a method of extracting a metal ion, which comprises contacting a compound of formula (R2SiO)n with a source of the metal ion, whereby the compound and the metal ion form a complex, wherein each R is independently C1-10alkyl, and n is 3-10. |
FILED | Tuesday, June 11, 2019 |
APPL NO | 16/438189 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium C01D 15/00 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/21 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 7/006 (20130101) C22B 26/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279628 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Ju Li (Weston, Massachusetts); Zhi Zhu (Malden, Massachusetts) |
ABSTRACT | Previous hybrid-anion and cation-redox (HACR) cathodes were limited in cycling performance by irreversible anionic redox reactions caused by the loss of anions. To overcome this limitation, a lithium (Li) transition metal (M) oxide particle is described having a Li concentration gradient. In one example, the particle includes a Li-rich core region that provides capacity and energy density due anionic and cationic contributions and a Li-poor surface region surrounding the core region to inhibit anionic activity and thus substantially reduce the loss of anions. A gradient region disposed between the core and surface regions has a Li concentration profile that varies from a first Li concentration in the core region to a second Li concentration in the surface region. A high-temperature leaching method may be used to leach LiO from a Li-rich Li1+xM1−XO2 particle, thus forming a coherent Li gradient with a stabilized layered structure. |
FILED | Monday, November 18, 2019 |
APPL NO | 16/687416 |
ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 45/1228 (20130101) C01G 51/42 (20130101) C01G 53/42 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/52 (20130101) C01P 2004/53 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279637 | Choi et al. |
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APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Kyoung-Shin Choi (Fitchburg, Wisconsin); Dohwan Nam (Madison, Wisconsin); Dong Ki Lee (Madison, Wisconsin) |
ABSTRACT | Electrodialysis cell systems for water deionization is provided. Also provided are methods for using the electrodialysis cell systems. The cells use the forward and reverse reactions of a redox mediator and the combined operations of a deionization cell and an ion-accumulation cell to enable sustainable deionization with a significantly decreased operating voltage, relative to conventional deionization cells. The cells have applications in seawater desalination, water purification, and wastewater treatment. |
FILED | Wednesday, November 07, 2018 |
APPL NO | 16/182696 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Separation B01D 61/46 (20130101) B01D 2311/25 (20130101) B01D 2313/345 (20130101) B01D 2313/365 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/4693 (20130101) Original (OR) Class C02F 2103/08 (20130101) C02F 2201/009 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279677 | Abrahamian et al. |
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APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
INVENTOR(S) | Ivan Abrahamian (Hanover, New Hampshire); Hai Qian (West Lebanon, New Hampshire); Susnata Pramanik (Hanover, New Hampshire); Baihao Shao (West Lebanon, New Hampshire); Quan Li (Hanover, New Hampshire) |
ABSTRACT | Provided herein are compounds for use as photochromic molecular switches having very long thermal isomerization half-lives and switchable fluorescence properties both in solution and the solid state. |
FILED | Thursday, May 02, 2019 |
APPL NO | 16/401942 |
ART UNIT | 1622 — Organic Chemistry |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/127 (20130101) B01J 2219/0879 (20130101) B01J 2219/1203 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/09 (20130101) Acyclic or Carbocyclic Compounds C07C 243/22 (20130101) C07C 251/00 (20130101) C07C 251/82 (20130101) C07C 251/86 (20130101) Heterocyclic Compounds C07D 215/40 (20130101) Original (OR) Class C07D 273/08 (20130101) C07D 333/24 (20130101) C07D 333/36 (20130101) C07D 401/12 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 9/02 (20130101) C09K 11/06 (20130101) C09K 2211/1007 (20130101) C09K 2211/1011 (20130101) C09K 2211/1014 (20130101) C09K 2211/1018 (20130101) Static Stores G11C 13/041 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279736 | Ly et al. |
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APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Danith H. Ly (Pittsburgh, Pennsylvania); Srinivas Rapireddy (Pittsburgh, Pennsylvania); Bichismita Sahu (Pittsburgh, Pennsylvania) |
ABSTRACT | The present invention relates to γ-PNA monomers according to Formula I where substituent groups R1, R2, R3, R4, R5, R6, B and P are defined as set forth in the specification. The invention also provides methodology for synthesizing compounds according to Formula I and methodology for synthesizing PNA oligomers that incorporate one or more Formula I monomers. |
FILED | Wednesday, August 26, 2020 |
APPL NO | 17/003131 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/60 (20170801) Acyclic or Carbocyclic Compounds C07C 229/12 (20130101) C07C 271/20 (20130101) Heterocyclic Compounds C07D 239/47 (20130101) C07D 239/54 (20130101) C07D 473/18 (20130101) C07D 473/34 (20130101) Peptides C07K 1/04 (20130101) C07K 1/08 (20130101) C07K 14/003 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279780 | Coates et al. |
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FUNDED BY |
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APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York); REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York); REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
INVENTOR(S) | Geoffrey Coates (Lansing, New York); James Eagan (Austin, Texas); Anne Lapointe (Ithaca, New York); Frank S. Bates (St. Louis Park, Minnesota) |
ABSTRACT | A semicrystalline multiblock copolymer includes alternating blocks of semicrystalline isotactic polypropylene (iPP) and semicrystalline polyethylene (PE), having a block arrangement according to formula (I): (iPPw)p(PEx)(iPPy)m(PEz)n (I), wherein p is 0 or 1; m is 0 or 1; n is 0 or 1; the sum of p, m, and n is 1, 2, or 3; and the sum of w, x, y, and z is greater than or equal to 40 kg/mol, with the provisos that: when m and n are 0, the sum of w and x is greater than or equal to 140 kg/mol; and when p and n are 0, the sum of y and x is greater than or equal to 140 kg/mol. Related compositions and methods are also provided. |
FILED | Friday, May 26, 2017 |
APPL NO | 16/303004 |
ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/12 (20130101) B32B 27/08 (20130101) B32B 27/12 (20130101) B32B 27/32 (20130101) B32B 2250/02 (20130101) B32B 2250/03 (20130101) B32B 2250/242 (20130101) B32B 2262/0253 (20130101) B32B 2307/54 (20130101) B32B 2307/518 (20130101) B32B 2307/748 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 4/64144 (20130101) C08F 4/64144 (20130101) C08F 10/00 (20130101) C08F 210/02 (20130101) C08F 210/06 (20130101) Original (OR) Class C08F 297/086 (20130101) Compositions of Macromolecular Compounds C08L 23/06 (20130101) C08L 23/06 (20130101) C08L 23/06 (20130101) C08L 23/14 (20130101) C08L 23/14 (20130101) C08L 23/14 (20130101) C08L 53/00 (20130101) C08L 53/00 (20130101) C08L 53/00 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 153/00 (20130101) C09J 153/00 (20130101) C09J 153/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279927 | Townsley et al. |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Brad Townsley (Oakland, California); Michael F. Covington (Oakland, California); Neelima Sinha (Oakland, California) |
ABSTRACT | Provided herein are compositions, kits and methods for the production of strand-specific cDNA libraries. The compositions, kits and methods utilize properties of double stranded polynucleotides, such as RNA-cDNA duplexes to capture and incorporate a novel sequencing adapter. The methods are useful transcriptome profiling by massive parallel sequence, such as full-length RNA sequencing (RNA-Seq) and 3′ tag digital gene expression (DGE). |
FILED | Friday, April 29, 2016 |
APPL NO | 15/569568 |
ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1096 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 2521/107 (20130101) C12Q 2521/107 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2525/179 (20130101) C12Q 2525/179 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2537/137 (20130101) C12Q 2537/137 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279956 | Lynch et al. |
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FUNDED BY |
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APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
INVENTOR(S) | Michael David Lynch (Durham, North Carolina); Zhixia Ye (Raleigh, North Carolina) |
ABSTRACT | The present disclosure provides compositions and methods for rapid production of chemicals in genetically engineered microorganisms in a large scale. Also provided herein is a high-throughput metabolic engineering platform enabling the rapid optimization of microbial production strains. The platform, which bridges a gap between current in vivo and in vitro bio-production approaches, relies on dynamic minimization of the active metabolic network. |
FILED | Wednesday, October 23, 2019 |
APPL NO | 16/661065 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/001 (20130101) C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/0016 (20130101) C12N 9/0051 (20130101) C12N 9/1025 (20130101) C12N 15/746 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/42 (20130101) Original (OR) Class C12P 13/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279974 | Lieberman-Aiden et al. |
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APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
INVENTOR(S) | Erez Lieberman-Aiden (Houston, Texas); Suhas Rao (Medfield, Massachusetts); Elena Stamenova (Reading, Massachusetts); Olga Dudchenko (Houston, Texas); Eric Lander (Cambridge, Massachusetts) |
ABSTRACT | Disclosed is an in situ method for detecting spatial proximity relationships between nucleic acid sequences, such as DNA, in a cell. The method includes: providing a sample of one or more cells comprising nucleic acids; fragmenting the nucleic acids present in the cells that leaves 5′ overhanging ends; filling in the overhanging ends with at least one labeled nucleotide; joining the filled in end of the fragmented nucleic acids that are in close physical proximity to create one or more end joined nucleic acid fragments having a junction; isolating the one or more end joined nucleic acid fragments using the labeled nucleotide; and determining the sequence at the junction of the one or more end joined nucleic acid fragments. |
FILED | Tuesday, December 01, 2015 |
APPL NO | 15/532353 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2521/501 (20130101) C12Q 2521/501 (20130101) C12Q 2521/501 (20130101) C12Q 2525/117 (20130101) C12Q 2525/117 (20130101) C12Q 2525/117 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2563/131 (20130101) C12Q 2563/131 (20130101) C12Q 2563/131 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 20/00 (20130101) C40B 30/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280034 | Yoon et al. |
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APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
INVENTOR(S) | Yong-Kyu Yoon (Gainesville, Florida); Pit Fee Jao (Gainesville, Florida) |
ABSTRACT | Various examples of methods and systems related to nanofibrous microstructures including carbon nanofibrous microelectrode arrays are provided. In one example, a method includes electrospinning photosensitive nanofibers on a patterned substrate; immersing the photosensitive nanofibers in a refractive index matching medium; and exposing the immersed photosensitive nanofibers to ultraviolet (UV) light through the patterned substrate or through a front side photomask. In another example, a microelectrode array includes a carbon thin film (CTF) trace pattern including a plurality of CTF electrode pads; and a plurality of carbon nanofiber (CNF) pillars disposed on the plurality of CTF electrode pads. |
FILED | Thursday, April 02, 2015 |
APPL NO | 15/301620 |
ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/24 (20210101) A61B 2562/125 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/04 (20130101) A61N 1/05 (20130101) Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/02 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/16 (20170801) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/38 (20130101) Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 1/728 (20130101) Original (OR) Class Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0035 (20130101) G03F 7/0037 (20130101) G03F 7/038 (20130101) G03F 7/2014 (20130101) G03F 7/2022 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280758 | Koh |
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APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Seong Jin Koh (Arlington, Texas) |
ABSTRACT | The invention relates generally to devices, systems, compositions, and methods for the detection of oligonucleotides, nucleic acids, antigens, antibodies, peptides, proteins, and non-biological molecules. |
FILED | Friday, January 13, 2017 |
APPL NO | 16/069651 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/00 (20130101) B01J 2219/00317 (20130101) B01J 2219/00648 (20130101) B01J 2219/00653 (20130101) B01J 2219/00722 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 20/00 (20130101) B82Y 30/00 (20130101) Apparatus for Enzymology or Microbiology; C12M 1/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6837 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/64 (20130101) G01N 27/4145 (20130101) G01N 27/4146 (20130101) Original (OR) Class G01N 33/5438 (20130101) G01N 2458/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280789 | Shen et al. |
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APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
INVENTOR(S) | Wei Shen (Roseville, Minnesota); Mengen Zhang (St. Paul, Minnesota); Bin Xu (Minneapolis, Minnesota) |
ABSTRACT | A cell-capturing substrate, methods of using the cell-capturing substrate that allow for label-free cell separation, and kits that incorporate the cell-capturing substrate. |
FILED | Wednesday, April 19, 2017 |
APPL NO | 15/491233 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6841 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11281096 | Kim et al. |
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APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
INVENTOR(S) | Seok Kim (Champaign, Illinois); Hohyun Keum (Champaign, Illinois); Jun Kyu Park (Champaign, Illinois) |
ABSTRACT | A method of making a bonded polymeric assembly by transfer printing comprises contacting a stamp with a solid-phase ink comprising a photoresist to form an inked stamp, where the solid-phase ink is reversibly bound to the stamp. The inked stamp is aligned with an object comprising the photoresist and is stamped onto the object. The stamp is then removed, thereby transferring the solid-phase ink onto the object. The solid-phase ink is thermally joined with the object. Thus, a bonded polymeric assembly comprising a bonded joint between the solid-phase ink and the object is formed. |
FILED | Thursday, July 18, 2019 |
APPL NO | 16/515431 |
ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 40/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11281545 | Solihin et al. |
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APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
INVENTOR(S) | Yan Solihin (Orlando, Florida); Mohammad Alshboul (Raleigh, North Carolina); James Tuck (Raleigh, North Carolina) |
ABSTRACT | Lazy Persistency (LP), a software persistency method that allows caches to slowly send dirty blocks to the non-volatile main memory (NVMM) through natural evictions. With LP, there are no additional writes to NVMM, no decrease in write endurance, and no performance degradation from cache line flushes and barriers. Persistency failures are discovered using software error detection (checksum), and the system recovers from them by recomputing inconsistent results. LP was evaluated and compared to the state-of-the-art Eager Persistency technique from prior work. Compared to Eager Persistency, LP reduces the execution time and write amplification overheads from 9% and 21% to only 1% and 3%, respectively. |
FILED | Monday, September 09, 2019 |
APPL NO | 16/564479 |
ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Electric Digital Data Processing G06F 11/1469 (20130101) Original (OR) Class G06F 12/12 (20130101) G06F 2201/82 (20130101) G06F 2212/1021 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11281826 | Patankar et al. |
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APPLICANT(S) | Northwestern University (Evanston, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Neelesh A. Patankar (Buffalo Grove, Illinois); Nishant Nangia (Vernon Hills, Illinois) |
ABSTRACT | Systems, methods, and computer readable media to simulate and predict translational and/or rotational velocity of a moving vehicle based on a determination of engine load for the vehicle are disclosed. An example vehicle motion simulator system includes a speed and stability predictor to simulate and predict a translational and rotational velocity of a moving vehicle based on a determination of engine load for the moving vehicle characterized by the speed and stability predictor. The example speed and stability predictor to execute instructions to at least: compute a nearest wall distance for the moving vehicle in an environment; solve an eddy viscosity for the environment; solve a flow velocity for the environment; and determine vehicle motion to characterize a speed and stability of the moving vehicle based on the wall distance, eddy viscosity, and flow velocity. |
FILED | Wednesday, December 20, 2017 |
APPL NO | 16/471339 |
ART UNIT | 2148 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Systems for Controlling or Regulating Non-electric Variables G05D 1/0212 (20130101) Electric Digital Data Processing G06F 30/15 (20200101) G06F 30/28 (20200101) Original (OR) Class Image Data Processing or Generation, in General G06T 17/20 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11281957 | Mangal et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Vivek Mangal (New York, New York); Peter R. Kinget (Summit, New Jersey) |
ABSTRACT | Backscatter tags, comprising: antennas; single pole, multiple throw switches each switch (S) having pole terminal connected to one of the antennas, and each having first throw terminal (TT) connected to first side (FS) of inductor (I) for S, second TT connected to FS of capacitor (C) for S, third TT connected to fixed voltage level (FVL), fourth TT that is floating, wherein second side (SS) of I and SS of C are connected to the FVL; power combiner (PC) having inputs connected to fifth TT of each of two of the switches; power detector (PD) having an input connected to output of PC; analog to digital converter (ADC) having input connected to output of PD; hardware processor coupled to output of the ADC and coupled to control terminal of each of the switches. |
FILED | Thursday, March 18, 2021 |
APPL NO | 17/205205 |
ART UNIT | 2876 — Optics |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10356 (20130101) G06K 19/0723 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 1/2208 (20130101) Transmission H04B 5/0062 (20130101) H04B 7/22 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11282616 | Watkins et al. |
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FUNDED BY |
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APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | James Watkins (South Hadley, Massachusetts); Michael R. Beaulieu (Chicopee, Massachusetts); Nicholas R. Hendricks (South Deerfield, Massachusetts) |
ABSTRACT | Aspects relate to patterned nanostructures having a feature size not including film thickness below 5 microns. The patterned nanostructures are made up of nanoparticles having an average particle size less than 100 nm. A nanoparticle composition, which, in some cases, includes a binder material, is applied to a substrate. A patterned mold used in concert with electromagnetic radiation manipulate the nanoparticle composition in forming the patterned nanostructure. In some embodiments, the patterned mold nanoimprints a suitable pattern onto the nanoparticle composition and the composition is cured through UV or thermal energy. Three-dimensional patterned nanostructures may be formed. A number of patterned nanostructure layers may be prepared and joined together. In some cases, a patterned nanostructure may be formed as a layer that is releasable from the substrate upon which it is initially formed. Such releasable layers may be arranged to form a three-dimensional patterned nanostructure in accordance with suitable applications. |
FILED | Monday, September 23, 2019 |
APPL NO | 16/578524 |
ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/08 (20130101) Original (OR) Class H01B 3/10 (20130101) H01B 13/003 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0015 (20130101) H01L 51/442 (20130101) H01L 51/5209 (20130101) H01L 2251/5369 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/04 (20130101) H01M 4/0433 (20130101) H01M 6/40 (20130101) H01M 8/124 (20130101) H01M 8/1286 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11282624 | Lu et al. |
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FUNDED BY |
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APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
ASSIGNEE(S) | THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida) |
INVENTOR(S) | Jun Lu (Tallahassee, Florida); Jeremy Levitan (Tallahassee, Florida) |
ABSTRACT | Tapes and coils for superconducting magnets are provided, along with methods of making the tapes and coils. In one embodiment, the coil includes a rare earth barium copper oxide (REBCO) superconducting tape; and a thin resistive layer of copper oxide, Cr, Ni, or Ni—P substantially coated onto the REBCO superconducting tape, wherein the coated REBCO superconducting tape is wound into a coil form. In another embodiment, the coil includes at least two REBCO superconducting tapes; and a stainless steel tape interlayer disposed between the at least two REBCO superconducting tapes, wherein the stainless steel tape comprises a plating layer of nickel or copper, and wherein the at least two REBCO superconducting tapes together with the stainless steel tape interlayer are wound into a coil form. |
FILED | Friday, February 22, 2019 |
APPL NO | 16/283187 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/342 (20130101) H01F 6/02 (20130101) H01F 6/06 (20130101) Original (OR) Class H01F 41/048 (20130101) H01F 41/061 (20160101) H01F 41/063 (20160101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11283238 | Cheng et al. |
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FUNDED BY |
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APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
INVENTOR(S) | Chiao-Yu Cheng (State College, Pennsylvania); Noel C. Giebink (State College, Pennsylvania) |
ABSTRACT | A method of generating a light-matter hybrid species of charged polaritons at room temperature includes providing an organic semiconductor microcavity being a doped organic semiconductor sandwiched in a microcavity capable of generating an optical resonance and coupling light to the polaron optical transition in the organic semiconductor microcavity thereby forming polaron-polaritons. The doped organic semiconductor may be a hole/electron transport material having a polaron absorption coefficient exceeding 102 cm−1 and capable of generating a polaron optical transition with a linewidth smaller than a predetermined threshold. The optical resonance of the microcavity has a resonance frequency matched with the polaron optical transition. |
FILED | Wednesday, November 14, 2018 |
APPL NO | 16/762541 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/002 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/36 (20130101) H01S 5/305 (20130101) H01S 5/0422 (20130101) H01S 5/1042 (20130101) Original (OR) Class H01S 5/18369 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 11278004 | Deng et al. |
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FUNDED BY |
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APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Z. Daniel Deng (Richland, Washington); Huidong Li (Richland, Washington); Chuan Tian (Richland, Washington); Jun Lu (Richland, Washington); Mitchell J. Myjak (Richland, Washington); Jayson J. Martinez (Richland, Washington); Jie Xiao (Richland, Washington); Yuxing Wang (Richland, Washington); Qiuyan Li (Richland, Washington) |
ABSTRACT | Animal transmitters are provided that can include: a transducer configured to transmit a signal; process circuitry coupled to the transducer; and an energy harvesting element coupled to the process circuitry. Animals having a transmitter coupled thereto are also provided with the transmitter including an energy harvesting element in operational alignment with the animal's musculoskeletal system. Methods for transmitting the location of an animal are also provided with the methods including: coupling a transmitter powered by an energy harvesting element to the animal; and monitoring the transmissions of the transmitter. |
FILED | Thursday, March 31, 2016 |
APPL NO | 15/088032 |
ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 11/006 (20130101) A01K 11/008 (20130101) Original (OR) Class A01K 29/005 (20130101) A01K 61/90 (20170101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 1/725 (20130101) Electric Machines Not Otherwise Provided for H02N 2/186 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278937 | Kumar et al. |
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FUNDED BY |
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APPLICANT(S) | Sortera Alloys, Inc. (Forth Worth, Texas) |
ASSIGNEE(S) | Sortera Alloys, Inc. (Fort Worth, Texas) |
INVENTOR(S) | Nalin Kumar (Fort Worth, Texas); Manuel Gerardo Garcia, Jr. (Lexington, Kentucky) |
ABSTRACT | A material sorting system sorts materials utilizing multiple stages of classification and sorting, including a vision system that implements a machine learning system in order to identify or classify each of the materials, and Laser Induced Breakdown Spectroscopy to perform a subsequent classification and sorting of the remaining materials. |
FILED | Thursday, September 30, 2021 |
APPL NO | 17/491415 |
ART UNIT | 3653 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 5/04 (20130101) B07C 5/34 (20130101) B07C 5/342 (20130101) B07C 5/3422 (20130101) Original (OR) Class B07C 2501/0054 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278957 | King et al. |
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FUNDED BY |
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APPLICANT(S) | FORGE NANO, INC. (Louisville, Colorado) |
ASSIGNEE(S) | FORGE NANO, INC. (Louisville, Colorado) |
INVENTOR(S) | David M. King (Sudbury, Massachusetts); Paul Lichty (Louisville, Colorado) |
ABSTRACT | The present invention provides various passive electronic components comprising a layer of coated particles, and methods for producing and using the same. Some of the passive electronic components of the invention include, but are not limited to conductors, resistors, current collectors, capacitors, piezoelectronic devices, inductors and transformers. The present invention also provides energy storage devices and electrode layers for such energy storage devices having passive, electrically-conductive particles coated with one or more thin film materials. |
FILED | Monday, February 24, 2020 |
APPL NO | 16/799229 |
ART UNIT | 2848 — Electrical Circuits and Systems |
CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/00 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/02 (20130101) B22F 1/0018 (20130101) B22F 1/025 (20130101) Original (OR) Class Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/34 (20130101) C23C 16/40 (20130101) C23C 16/0236 (20130101) C23C 16/403 (20130101) C23C 16/442 (20130101) C23C 16/4417 (20130101) C23C 16/45525 (20130101) C23C 16/45555 (20130101) C23C 18/1216 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/008 (20130101) H01G 4/30 (20130101) H01G 4/33 (20130101) H01G 4/0085 (20130101) H01G 4/1227 (20130101) H01G 11/24 (20130101) H01G 11/30 (20130101) H01G 11/46 (20130101) H01G 11/50 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/62 (20130101) H01M 4/366 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278960 | Tappan et al. |
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FUNDED BY |
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APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Bryce Tappan (Santa Fe, New Mexico); Andrew Schmalzer (Los Alamos, New Mexico); Alexander Mueller (Santa Fe, New Mexico) |
ABSTRACT | Processes for tailoring the macroscopic shape, metallic composition, mechanical properties, and pore structure of nanoporous metal foams prepared through combustion synthesis via direct write 3D printing of metal energetic ligand precursor inks made with water and an organic thickening agent are disclosed. Such processes enable production of never before obtainable metal structures with hierarchical porosity, tailorable from the millimeter size regime to the nanometer size regime. Structures produced by these processes have numerous applications including, but not limited to, catalysts, heat exchangers, low density structural materials, biomedical implants, hydrogen storage medium, fuel cells, and batteries. |
FILED | Thursday, April 11, 2019 |
APPL NO | 16/381074 |
ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1121 (20130101) Original (OR) Class B22F 10/00 (20210101) B22F 10/60 (20210101) B22F 2998/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/52 (20130101) Alloys C22C 1/08 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/092 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11278978 | Schultz |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Mark D. Schultz (Ossining, New York) |
ABSTRACT | An apparatus includes a fin pack of parallel plates that protrude from a base, a lid attachable to the fin pack opposite the base, and a brazing material painted onto the lid only in a plurality of wettable regions. The lid is positioned against the fin pack, opposite the base, with portions of the plurality of regions contacting edges of the parallel plates. The lid is brazed to the fin pack without intrusion of the brazing material between the parallel plates. This is accomplished by obtaining a lid to be attached to a fin pack of parallel plates that protrude from a base, painting the lid with the brazing material only in a plurality of wettable regions, positioning the lid against the fin pack, opposite the base, with portions of the plurality of regions contacting edges of the parallel plates, and brazing the lid to the fin pack. |
FILED | Friday, June 21, 2019 |
APPL NO | 16/448574 |
ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 1/0012 (20130101) B23K 1/0016 (20130101) B23K 1/203 (20130101) Original (OR) Class B23K 3/0638 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 3/048 (20130101) F28F 2275/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279049 | Dilday, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
INVENTOR(S) | Daniel R. Dilday, Jr. (Plainfield, Illinois); Roberto T. Reyes (Ottawa, Illinois); Stanley G. Weidmeyer (Glen Ellyn, Illinois) |
ABSTRACT | The invention provides a system for preventing fluid exchange between the interior and exterior of containment enclosures such as process-, hazard-, and research-enclosure systems generally, gloveboxes, containment systems, isolation systems, confinement systems, cleanrooms, negative air systems, and positive air system areas while simultaneously providing material transfer into and out of the enclosures. The invention also provides a method for transporting material into or out of a containment structure. |
FILED | Tuesday, August 15, 2017 |
APPL NO | 15/677290 |
ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 1/02 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 21/02 (20130101) Original (OR) Class Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 7/047 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49826 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279080 | Barr et al. |
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FUNDED BY |
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APPLICANT(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri) |
ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
INVENTOR(S) | Christian G. Barr (Kansas City, Missouri); George W. Bohnert (Harrisonville, Missouri) |
ABSTRACT | Methods and assemblies for additive manufacturing portions of components with enhanced strength are provided. The assemblies comprise a first deposition head and an apparatus for causing one or more reinforcement fibers to extend more than two layers within previously-deposited layers of build material. The first deposition head is configured to deposit a plurality of layers of a filament comprising a reinforcement fiber and thermoplastic material. The apparatus may comprise a needle point configured to be inserted into the plurality of layers to displace the reinforcement fiber so that it extends two or more of the plurality of layers. The apparatus may additionally or alternatively comprise a second deposition head having a needle tip configured to be inserted into the plurality of layers to inject a length of a second filament comprising thermoplastic material and a reinforcement fiber so that the reinforcement fiber of the second filament extends two or more layers of the plurality of layers of the first filament. |
FILED | Friday, December 06, 2019 |
APPL NO | 16/705363 |
ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/25 (20170801) B29C 64/118 (20170801) Original (OR) Class B29C 64/188 (20170801) B29C 64/209 (20170801) B29C 64/227 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279642 | Arnett et al. |
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FUNDED BY |
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APPLICANT(S) | United States of America as Represented by The Secretary of the Army (Alexandria, Virginia) |
ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
INVENTOR(S) | Clint M Arnett (Mahomet, Illinois); Martin A Page (Urbana, Illinois); Donald M Cropek (Champaign, Illinois); Ashley N Boyd (Champaign, Illinois); Justin Lange (Mahomet, Illinois) |
ABSTRACT | A recombinant Moringa oleifera coagulant protein (MO) produced and secreted by Bacillus has coagulation/flocculation activity. The MO protein and the Bacillus host cells expressing the MO protein can be used in compositions and methods for treating contaminated water, such as drinking water or waste water. The MO protein can coagulate or flocculate suspended solid impurities in the water, which can then be removed. |
FILED | Wednesday, September 25, 2019 |
APPL NO | 16/582959 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 3/34 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/75 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279666 | Saboe et al. |
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FUNDED BY |
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APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
INVENTOR(S) | Patrick Owen Saboe (Golden, Colorado); Eric M. Karp (Denver, Colorado); Lorenz Perry Manker (Jamaica Plain, Massachusetts); Hanna Rose Monroe (Broomfield, Colorado) |
ABSTRACT | Disclosed herein are methods for the recovery of target bio-base carboxylic acid products using a sorption-based technology with a mixed elution solvent optimized for minimized downstream distillation energy input. The sorption-based technology includes absorbing the targeted bio-base carboxylic acid products onto a non-ionic resin and eluting the targeted bio-base carboxylic acid products with a mixed elution solvent. The mixed elution solvent includes a first solvent and a second solvent. The first solvent has a boiling point that is lower than the targeted bio-base carboxylic acid products and the second solvent is selected from the group consisting of a phosphine oxide or tertiary amine. |
FILED | Thursday, July 30, 2020 |
APPL NO | 16/942888 |
ART UNIT | 1622 — Organic Chemistry |
CURRENT CPC | Separation B01D 3/40 (20130101) B01D 3/143 (20130101) B01D 17/0202 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/261 (20130101) B01J 20/3425 (20130101) B01J 20/3475 (20130101) Acyclic or Carbocyclic Compounds C07C 51/44 (20130101) C07C 51/47 (20130101) Original (OR) Class Apparatus for Enzymology or Microbiology; C12M 47/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279749 | Hoeprich, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
INVENTOR(S) | Paul D. Hoeprich, Jr. (Pleasanton, California); Julio A. Camarero (San Gabriel, California) |
ABSTRACT | Synthetic apolipoproteins based on native/naturally occurring homolog proteins can be prepared using solid-phase peptide synthesis approaches combined with native chemical ligation methods to create analogs of full length apolipoproteins. The chemical synthesis is expected to allow introduction of non-natural amino acids, e.g., α,α′-dialkyl amino acids, with a periodicity that encourages both helix formation and amphipathicity. Such apolipoprotein analogs are expected to encourage, in some embodiments, facile and more complete NLP formation, enabling consideration of full spectrum of nanoparticle-based biotechnology applications ranging from therapeutic sequestration and delivery to energy/biofuel production to biopolymer production. |
FILED | Friday, September 09, 2016 |
APPL NO | 15/744754 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 1/006 (20130101) C07K 1/113 (20130101) C07K 1/1077 (20130101) C07K 14/775 (20130101) Original (OR) Class Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/24 (20130101) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 10/00 (20190201) |
VIEW PATENT | @ USPTO: Full Text PDF |
11279805 — Plasticized terephthalate-based polyester blends containing fatty acids or esters thereof
US 11279805 | Naskar et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (Knoxville, Tennessee) |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (Knoxville, Tennessee) |
INVENTOR(S) | Amit K. Naskar (Knoxville, Tennessee); Kokouvi Akato (Bear, Delaware); Ngoc A. Nguyen (Oak Ridge, Tennessee); David P. Harper (Maryville, Tennessee) |
ABSTRACT | A plasticized terephthalate-based polyester blend comprising a terephthalate-based polyester (e.g., polyethylene terephthalate, i.e., PET) homogeneously blended with a fatty acid or ester thereof, wherein said fatty acid or ester thereof is present in said polyester blend in an amount of 1-50 wt %. Also described herein is a method for producing a plasticized terephthalate-based polyester blend, the method comprising melt mixing a terephthalate-based polyester with a fatty acid or ester thereof at a temperature in a range of 230-250° C. to produce said polyester blend, wherein said fatty acid or ester thereof is present in said polyester blend in an amount of 1-50 wt % and is homogeneously blended with said terephthalate-based polyester. |
FILED | Tuesday, July 23, 2019 |
APPL NO | 16/519396 |
ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/18 (20130101) Original (OR) Class C08J 3/201 (20130101) C08J 2367/02 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/09 (20130101) C08K 5/101 (20130101) Compositions of Macromolecular Compounds C08L 97/005 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11279882 | Thorson et al. |
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FUNDED BY |
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APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Michael R. Thorson (Richland, Washington); Lesley J. Snowden-Swan (Ellensburg, Washington); Andrew J. Schmidt (Richland, Washington); Todd R. Hart (Kennewick, Washington); Justin M. Billing (Richland, Washington); Daniel B. Anderson (Pasco, Washington); Richard T. Hallen (Richland, Washington) |
ABSTRACT | A hydrothermal liquefaction (HTL) system can comprise a biomass slurry source, a first pump in fluid communication with the slurry source and configured to pressurize a biomass slurry stream from the slurry source to a first pressure, a first heat exchanger in fluid communication with the first pump and configured to heat a slurry stream received from the first pump to a first temperature, a second pump in fluid communication with the first heat exchanger and configured to pressurize a slurry stream received from the first heat exchanger to a second pressure higher than the first pressure, a second heat exchanger in fluid communication with the second pump and configured to heat a slurry stream received from the second pump to a second temperature higher than the first temperature, and a HTL reactor configured to produce biocrude from a slurry stream received from the second heat exchanger. |
FILED | Friday, January 10, 2020 |
APPL NO | 16/740339 |
ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 1/065 (20130101) Original (OR) Class C10G 2300/1011 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 3/08 (20130101) C10L 2200/0469 (20130101) C10L 2290/06 (20130101) C10L 2290/46 (20130101) C10L 2290/543 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280019 | Abas et al. |
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FUNDED BY |
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APPLICANT(S) | SUNPOWER CORPORATION (San Jose, California) |
ASSIGNEE(S) | SunPower Corporation (San Jose, California) |
INVENTOR(S) | Emmanuel Chua Abas (Laguna, Philippines); Chen-An Chen (Milpitas, California); Diana Xiaobing Ma (Saratoga, California); Kalyana Bhargava Ganti (Fremont, California); Edmundo Anida Divino (Cavite, Philippines); Jake Randal G. Ermita (Laguna, Philippines); Jose Francisco S. Capulong (Laguna, Philippines); Arnold Villamor Castillo (Laguna, Philippines) |
ABSTRACT | One embodiment relates to a substrate carrier for use in electroplating a plurality of substrates. The substrate carrier comprises a non-conductive carrier body on which the substrates are to be held. Electrically-conductive lines are embedded within the carrier body, and a plurality of contact clips are coupled to the electrically-conductive lines embedded within the carrier body. The contact clips hold the substrates in place and electrically couple the substrates to the electrically-conductive lines. The non-conductive carrier body is continuous so as to be impermeable to flow of electroplating solution through the non-conductive carrier body. Other embodiments, aspects and features are also disclosed. |
FILED | Wednesday, June 19, 2019 |
APPL NO | 16/445675 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 17/001 (20130101) Original (OR) Class C25D 17/005 (20130101) C25D 17/007 (20130101) C25D 17/08 (20130101) C25D 17/10 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/10 (20150115) Y10T 156/1057 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280173 | Buerger et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Stephen Buerger (Albuquerque, New Mexico); Anirban Mazumdar (Albuquerque, New Mexico); Steven James Spencer (Albuquerque, New Mexico); Timothy James Blada (Albuquerque, New Mexico); Jiann-Cherng Su (Albuquerque, New Mexico); Elton K. Wright (Rio Rancho, New Mexico); Adam Foris (Albuquerque, New Mexico); David W. Raymond (Edgewood, New Mexico) |
ABSTRACT | A system or method for drilling includes autonomously controlling a rotary or percussive drilling process as it transitions through multiple materials with very different dynamics. The method determines a drilling medium based on real-time measurements and comparison to prior drilling data, and identifies the material type, drilling region, and approximately optimal setpoint based on data from at least one operating condition. The controller uses these setpoints initially to execute an optimal search to maximize performance by minimizing mechanical specific energy. Near-bit depth-of-cut estimations are performed using a machine learning prediction deployed in an embedded processor to provide high-speed ROP estimates. The sensing capability is coupled with a near-bit clutching mechanism to support drilling dysfunction mitigation. |
FILED | Monday, January 25, 2021 |
APPL NO | 17/157614 |
ART UNIT | 2857 — Printing/Measuring and Testing |
CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 1/38 (20200501) E21B 44/08 (20130101) Original (OR) Class E21B 49/003 (20130101) E21B 2200/22 (20200501) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11280642 | Subbaraman et al. |
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FUNDED BY |
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APPLICANT(S) | BOISE STATE UNIVERSITY (Boise, Idaho) |
ASSIGNEE(S) | Boise State University (Boise, Idaho) |
INVENTOR(S) | Harish Subbaraman (Boise, Idaho); Sohel Rana (Boise, Idaho); Nirmala Kandadai (Boise, Idaho) |
ABSTRACT | A reflection mode sensor system may include an optical fiber core and an optical fiber cladding. A first long period grating (LPG) may be positioned along the optical fiber core having a first grating period, a second LPG may be positioned along the optical fiber core having a second grating period, and a third LPG may be positioned along the optical fiber core having a third grating period. The grating periods may enable sensing of multiple parameters simultaneously. A metal coating may be applied to an end facet of the combined optical fiber core and optical fiber cladding. The metal coating may also cover a side surface of the optical fiber cladding along a length from the end facet. The metal coating may include a paste applied to the optical fiber core and the optical fiber cladding, where the paste has been cured, and includes a metal. |
FILED | Thursday, June 11, 2020 |
APPL NO | 16/899308 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/16 (20130101) Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/35354 (20130101) Original (OR) Class Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/32 (20130101) Optical Elements, Systems, or Apparatus G02B 6/02095 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11281964 | Aimone et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | James Bradley Aimone (Albuquerque, New Mexico); William Mark Severa (Albuquerque, New Mexico); Richard B. Lehoucq (Albuquerque, New Mexico); Ojas D. Parekh (Albuquerque, New Mexico) |
ABSTRACT | A method for increasing a speed or energy efficiency at which a computer is capable of modeling a plurality of random walkers. The method includes defining a virtual space in which a plurality of virtual random walkers will move among different locations in the virtual space. The method also includes either assigning a corresponding set of ringed neurons in a spiking neural network to a corresponding virtual random walker, or assigning a corresponding set of ringed neurons to a point in the virtual space. Movement of a given virtual random walker is tracked by decoding differences between states of individual neurons in a corresponding given set of ringed neurons. A virtual random walk of the plurality of virtual random walkers is executed using the spiking neural network. |
FILED | Wednesday, June 27, 2018 |
APPL NO | 16/020619 |
ART UNIT | 2122 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/049 (20130101) Original (OR) Class G06N 3/063 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11283084 | Tucker et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Michael C. Tucker (Piedmont, California); Emir Dogdibegovic (Oakland, California) |
ABSTRACT | This disclosure provides systems, methods, and apparatus related to electrode structures. In one aspect, a method includes: providing an electrode layer comprising a ceramic, the ceramic being porous; providing a catalyst precursor, the catalyst precursor being a cathode catalyst precursor or an anode catalyst precursor; infiltrating the catalyst precursor in a first side of the electrode layer; after the infiltrating operation, heating the electrode layer to about 750° C. to 950° C., the catalyst precursor forming a catalyst, the catalyst being a cathode catalyst or an anode catalyst; infiltrating the catalyst precursor in the first side of the electrode layer; after the infiltrating operation, heating the electrode layer to about 300° C. to 700° C., the catalyst precursor forming the catalyst, the catalyst being the cathode catalyst or the anode catalyst. |
FILED | Wednesday, May 02, 2018 |
APPL NO | 15/968917 |
ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/885 (20130101) H01M 4/8621 (20130101) H01M 4/8842 (20130101) H01M 4/8846 (20130101) H01M 4/8882 (20130101) Original (OR) Class H01M 4/8885 (20130101) H01M 8/1007 (20160201) H01M 2008/1293 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11283257 | Hong et al. |
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FUNDED BY |
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APPLICANT(S) | Hitachi Energy Switzerland AG (Baden, Switzerland) |
ASSIGNEE(S) | Hitachi Energy Switzerland AG (Baden, Switzerland) |
INVENTOR(S) | Junho Hong (Cary, North Carolina); Reynaldo Nuqui (Cary, North Carolina) |
ABSTRACT | An example method for detecting and mitigating attacks on electric power substations comprises detecting a command to open or close a circuit breaker in the electric power substation. A modified extended substation model for the electric power substation is generated, based on the detected command and based on measurements in substation, where the modified extended substation model is a power flow model for the substation and for one or more directly connected neighboring substations. A power flow analysis is performed, using the modified extended substation model, to generate a predicted voltage for each of a plurality of nodes in the substation and in the one or more directly connected neighboring substations. Each predicted voltage is compared to a corresponding allowable voltage range, and execution of the command is blocked in response to determining that one or more of the voltages is outside the corresponding allowable voltage range. |
FILED | Tuesday, August 21, 2018 |
APPL NO | 16/107098 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Emergency Protective Circuit Arrangements H02H 7/262 (20130101) Original (OR) Class H02H 7/263 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11283363 | Raju |
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FUNDED BY |
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APPLICANT(S) | Ravisekhar Nadimpalli Raju (Clifton Park, New York) |
ASSIGNEE(S) | |
INVENTOR(S) | Ravisekhar Nadimpalli Raju (Clifton Park, New York) |
ABSTRACT | A modular power conversion system is provided which includes a plurality of building blocks comprised of transformers and power conversion bridges, and a high frequency AC link that transfers power and provides galvanic isolation between the building blocks. The high frequency link includes an insulating tube separating an AC link conductor and the building blocks. The insulating tube is further provided with conductive or semiconductive layers on its inner and outer surfaces for referencing them to the electric potentials of the adjacent conductors and windings, thereby placing the high electric fields substantially directly across the tube and reducing electric fields and partial discharge or corona in the adjoining space or media. The building blocks may be arranged in multiple stacks for DC or AC interface, preferably with neutral or lower voltage connections at the outer edges of the stacks and higher voltage terminals at the centers of the stack. |
FILED | Wednesday, August 19, 2020 |
APPL NO | 16/997573 |
ART UNIT | 2896 — Electrical Circuits and Systems |
CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/0067 (20210501) H02M 1/0074 (20210501) H02M 1/0077 (20210501) H02M 5/10 (20130101) H02M 5/293 (20130101) Original (OR) Class H02M 7/2173 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11283430 | Wu |
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FUNDED BY |
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APPLICANT(S) | Fermi Research Alliance, LLC (Batavia, Illinois) |
ASSIGNEE(S) | Fermi Research Alliance, LLC (Batavia, Illinois) |
INVENTOR(S) | Jinyuan Wu (Aurora, Illinois) |
ABSTRACT | A pure digital ring oscillator with constant power consumption as oscillation frequency is adjusted. Circuit topology includes a multiplexer implemented in NAND gates and a delay element positioned after a path selection NAND gate of that multiplexer such that delay element transistors may not toggle if the non-delaying signal path is selected. Assuming a delay element oscillation frequency f and a total capacitance C, and also assuming a plurality N of delay gates each characterized by a propagation delay t1 and a capacitance C1 such that C=C1*N, the ring oscillator of the present invention is characterized by a C value that is proportional to N and an f value that is inversely proportional to N. Furthermore, each of the N delay gates as well as the input and output gates of the multiplexer are characterized by a common capacitance-to-propagation delay ratio=C1/t1. |
FILED | Tuesday, June 30, 2020 |
APPL NO | 16/916473 |
ART UNIT | 2849 — Electrical Circuits and Systems |
CURRENT CPC | Pulse Technique H03K 3/012 (20130101) H03K 3/0315 (20130101) Original (OR) Class H03K 5/00 (20130101) H03K 19/20 (20130101) H03K 2005/00078 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11284255 | Akkaya et al. |
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FUNDED BY |
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APPLICANT(S) | The Florida International University Board of Trustees (Miami, Florida); Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida); BATTELLE ENERGY ALLIANCE, LLC (Idaho Falls, Idaho) |
INVENTOR(S) | Kemal Akkaya (Miami, Florida); Arupjyoti Bhuyan (Idaho Falls, Idaho); Mai A. M. Abdelmalek (Miami, Florida) |
ABSTRACT | A lightweight, fast, and reliable authentication mechanism compatible with the 5G D2D ProSe standard mechanisms is provided. A distributed authentication with a delegation-based scheme avoids repeated access to the 5G core network key management functions. Hence, a legitimate user equipment device (e.g., a drone) is authorized by the cellular network (e.g., 5G cellular network) via offering a proxy signature to authenticate itself to other drones. Test results demonstrate that the protocol is lightweight and reliable. |
FILED | Tuesday, April 27, 2021 |
APPL NO | 17/241257 |
ART UNIT | 2436 — Cryptography and Security |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3247 (20130101) H04L 63/0435 (20130101) Wireless Communication Networks H04W 12/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11284510 | Nicholas et al. |
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FUNDED BY |
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APPLICANT(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
ASSIGNEE(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
INVENTOR(S) | Jason Dale Nicholas (Okemos, Michigan); Quan Zhou (Farmington Hills, Michigan); Thomas Rector Bieler (East Lansing, Michigan) |
ABSTRACT | The disclosure generally relates to a method of creating patterned metallic circuits (e.g., silver circuits) on a substrate (e.g., a ceramic substrate). A porous metal interlayer (e.g., porous nickel) is applied to the substrate to improve wetting and adhesion of the patterned metal circuit material to the substrate. The substrate is heated to a temperature sufficient to melt the patterned metal circuit material but not the porous metal interlayer. Spreading of molten metal circuit material on the substrate is controlled by the porous metal interlayer, which can itself be patterned, such as having a defined circuit pattern. Thick-film silver or other metal circuits can be custom designed in complicated shapes for high temperature/high power applications. The materials designated for the circuit design allows for a low-cost method of generating silver circuits other metal circuits on a ceramic substrate. |
FILED | Wednesday, April 17, 2019 |
APPL NO | 16/386576 |
ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0306 (20130101) Original (OR) Class H05K 3/22 (20130101) H05K 3/1208 (20130101) H05K 3/3478 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 11280669 | Gorman et al. |
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FUNDED BY |
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APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
INVENTOR(S) | Jason John Gorman (Silver Spring, Maryland); Lei Shao (Clarksburg, Maryland) |
ABSTRACT | A pulsed laser interferometer includes: a pulsed laser; a vibration controller that produces a vibration control signal that controls a vibrational frequency and vibrational amplitude of a structural member; an interferometer controller; a pathlength control stage that changes an optical pathlength for laser pulses; a pathlength reflector that moves in concert with the pathlength control stage to change the optical pathlength of propagation for the laser pulses; a light pulse detector that produces a light pulse detector signal; an interference light detector that produces an interference frequency signal; a signal mixer that produces a reference frequency signal; and a phase-sensitive detector that produces a vibrational amplitude signal and a vibrational phase signal from the interference frequency signal referenced to the reference frequency signal. |
FILED | Monday, May 18, 2020 |
APPL NO | 16/876728 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 9/008 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11283002 | Shainline et al. |
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FUNDED BY |
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APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
INVENTOR(S) | Jeffrey M. Shainline (Boulder, Colorado); Manuel A. Castellanos-Beltran (Broomfield, Colorado); Adam N. McCaughan (Denver, Colorado); Sae Woo Nam (Boulder, Colorado) |
ABSTRACT | A primary single photon optoelectronic neuron includes a photonic synaptic input waveguide; an optoelectronic synapse; a synapto-dendritic electrical connection in communication with the optoelectronic synapse; an electronic dendrite in communication with the synapto-dendritic electrical connection; a dendrite-neuronal electrical interface in communication with the electronic dendrite; an integrator in communication with the dendrite-neuronal electrical interface; a superconducting wire in communication with the integrator; an axon hillock electronic-to-photonic transducer in communication with the superconducting wire; and an axonic waveguide in communication with the axon hillock electronic-to-photonic transducer and that receives the axonic photonic signal. Producing an axonic photonic signal by a primary single photon optoelectronic neuron includes producing an optoelectronic synapse electronic output signal; producing an electronic dendrite electrical output signal from the optoelectronic synapse electronic output signal; producing an axonic electrical signal from the optoelectronic synapse electronic output signal; and producing the axonic photonic signal from the axonic electrical signal. |
FILED | Friday, August 16, 2019 |
APPL NO | 16/542913 |
ART UNIT | 2849 — Semiconductors/Memory |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/44 (20130101) Electric Digital Data Processing G06F 1/08 (20130101) G06F 15/78 (20130101) Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) G06N 3/063 (20130101) G06N 3/067 (20130101) G06N 3/088 (20130101) G06N 3/0675 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/223 (20130101) Original (OR) Class Amplifiers H03F 19/00 (20130101) Pulse Technique H03K 3/0315 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 11278521 | Patel et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); The United States Government as Represented by The Department of Veterans Affairs (Washington, District of Columbia) |
ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS OFFICE OF GENERAL COUNSEL PSG IV (024) (Washington, District of Columbia) |
INVENTOR(S) | Niketa A. Patel (Tampa, Florida); Jianfeng Cai (Tampa, Florida) |
ABSTRACT | Provided herein are compounds that can bind GAS5 long non-coding RNA, compositions thereof, and uses thereof. |
FILED | Thursday, December 15, 2016 |
APPL NO | 16/063077 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/395 (20130101) Original (OR) Class A61K 45/06 (20130101) Heterocyclic Compounds C07D 285/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US D946722 | Cooper et al. |
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FUNDED BY |
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APPLICANT(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia); University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia); University of Pittsburgh Of The Commonwealth System Of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Rory A. Cooper (Gibsonia, Pennsylvania); Rosemarie Cooper (Gibsonia, Pennsylvania) |
ABSTRACT | |
FILED | Thursday, September 17, 2020 |
APPL NO | 29/750934 |
ART UNIT | 2925 — Design |
CURRENT CPC | Environmental heating and cooling; fluid handling and sanitary equipment D23/309 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 11279452 | Allen et al. |
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FUNDED BY |
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APPLICANT(S) | University of Maine System Board of Trustees (Orono, Maine) |
ASSIGNEE(S) | University of Maine System Board of Trustees (Orono, Maine) |
INVENTOR(S) | Christopher K. Allen (Bangor, Maine); Anthony M. Viselli (Bangor, Maine); Andrew J. Goupee (Ellsworth, Maine); Habib J. Dagher (Veazie, Maine); Robert E. Berry (Madison, Alabama); Jeffrey L. Lindner (Madison, Alabama); Frederick S. Gant (Huntsville, Alabama); John S. Townsend (Union Grove, Alabama); Rebecca L. Williams (Huntsville, Alabama) |
ABSTRACT | A motion absorbing system and method for a structure includes the coupling of a container to a structure. The container has a liquid disposed therein wherein a ullage is defined above a surface of the liquid. An elastic element is positioned in the liquid. The elastic element has a natural frequency tuned to damp motion of the liquid. |
FILED | Friday, May 07, 2021 |
APPL NO | 17/314201 |
ART UNIT | 3617 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 35/44 (20130101) B63B 39/02 (20130101) B63B 39/03 (20130101) Original (OR) Class B63B 79/15 (20200101) B63B 2035/446 (20130101) Wind Motors F03D 13/25 (20160501) Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2240/93 (20130101) F05B 2240/95 (20130101) F05B 2260/964 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11283187 | Goldsmith et al. |
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FUNDED BY |
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APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); UNIVERSITY OF MIAMI (Miami, Florida) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); UNIVERSITY OF MIAMI (Miami, Florida) |
INVENTOR(S) | Paul F. Goldsmith (Pasadena, California); Lorene A. Samoska (Pasadena, California); Maria Alonso Del Pino (Pasadena, California); Joshua O. Gundersen (Miami, Florida); Pekka Kangaslahti (Pasadena, California) |
ABSTRACT | Double reflector electromagnetic systems implementable in miniaturized satellites and other applications for compact, light weight, and broadband antennas. The disclosed methods and devices include primary and secondary reflectors, where the secondary reflector is held in the aperture plane of the primary reflector to minimize required space. A specific Cassegrain configuration is also described. |
FILED | Thursday, January 23, 2020 |
APPL NO | 16/750663 |
ART UNIT | 2644 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/288 (20130101) H01Q 19/19 (20130101) Original (OR) Class Transmission H04B 7/18576 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 11278041 | Johnston et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); DANISCO US INC. (Palo Alto, California) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); DANISCO US INC. (Palo Alto, California) |
INVENTOR(S) | David Johnston (Wyndmoor, Pennsylvania); Jayarama K. Shetty (Pleasanton, California); Bart C. Koops (Zuid Holland, Netherlands) |
ABSTRACT | Processes of treating grain (e.g., corn), involving milling the grain to produce milled grain wherein the grain germ remains intact in the milled grain, and producing a mixture by mixing the milled grain with water and at least one enzyme selected from the group consisting of protease, alpha amylase, glucoamylase, cell wall degrading enzyme, and mixtures thereof, wherein the pH of the mixture is optionally adjusted to a pH of about 3.5 to about 6.5, and incubating the mixture for about 1 to about 3 hours to produce an incubated mixture. |
FILED | Thursday, January 30, 2020 |
APPL NO | 16/777103 |
ART UNIT | 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Fodder A23K 10/12 (20160501) Original (OR) Class A23K 10/14 (20160501) A23K 10/30 (20160501) Preparing Grain for Milling; Refining Granular Fruit to Commercial Products by Working the Surface B02B 3/00 (20130101) Crushing, Pulverising, or Disintegrating in General; Milling Grain B02C 11/08 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) C12P 19/02 (20130101) C12P 19/14 (20130101) C12P 2201/00 (20130101) Enzymes C12Y 304/00 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
US 11279011 | Regan et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
INVENTOR(S) | Mary Shalane Regan (Groton, Connecticut); James P. Sullivan (Elizabeth City, North Carolina) |
ABSTRACT | In an example, a negator spring tool for winding a negator spring output drum around a rotational axis includes: a pair of tool handles; and a tool disk having an outer edge which is generally circular except for a cutout forming a portion of the outer edge as a cutout edge portion of the outer edge. The tool disk is configured to be releasably attached to the output drum. The tool disk has a drum-facing side which includes protruding teeth protruding from the drum-facing side to engage radial spokes of the output drum when they are pushed into the output drum and the tool disk is rotated in either circumferential direction around the rotational axis. The outer edge of the tool disk includes handle slots which are spaced circumferentially. The distal end of each tool handle is insertable into a handle slot to rotate the tool disk around the rotational axis. |
FILED | Thursday, May 13, 2021 |
APPL NO | 17/320072 |
ART UNIT | 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Tools or Bench Devices Not Otherwise Provided For, for Fastening, Connecting, Disengaging or Holding B25B 27/306 (20130101) Original (OR) Class Aeroplanes; Helicopters B64C 1/1423 (20130101) Hinges or Suspension Devices for Doors, Windows or Wings E05D 13/1284 (20130101) Indexing Scheme Relating to Hinges or Other Suspension Devices for Doors, Windows or Wings and Devices for Moving Wings into Open or Closed Position, Checks for Wings and Wing Fittings Not Otherwise Provided For, Concerned With the Functioning of the Wing E05Y 2900/502 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
US 11278633 | Yang et al. |
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FUNDED BY |
|
APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Aimei Yang (Cambridge, Massachusetts); Demian Park (Cambridge, Massachusetts); Kiryl Piatkevich (Cambridge, Massachusetts); Edward Boyden (Cambridge, Massachusetts) |
ABSTRACT | The invention, in some aspects, relates to dummy-fluorescent (DF) polypeptide molecules and their encoding nucleic acid molecules and use of such molecules in fusion proteins and their encoding nucleic acid molecules. Compositions of the invention may be delivered to cells and subjects and used in methods to modulate electrical activity of cells in which they are expressed, and for treatment of diseases and conditions in subjects. |
FILED | Thursday, July 20, 2017 |
APPL NO | 16/318428 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0045 (20130101) Original (OR) Class Peptides C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 11278697 | Galbraith et al. |
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FUNDED BY |
|
APPLICANT(S) | Separation Design Group IP Holdings, LLC (Waynesburg, Pennsylvania) |
ASSIGNEE(S) | SEPARATION DESIGN GROUP IP HOLDINGS, LLC (Waynesburg, Pennsylvania) |
INVENTOR(S) | Stephen Douglas Galbraith (Waynesburg, Pennsylvania); Kenneth J. McGowan (Waynesburg, Pennsylvania); Evonne A. Baldauff (Waynesburg, Pennsylvania); Elise N. Depetris (Waynesburg, Pennsylvania); David K. Walker (Waynesburg, Pennsylvania) |
ABSTRACT | Lightweight, portable oxygen concentrators that operate using an ultra rapid, sub one second, adsorption cycle based on advanced molecular sieve materials are disclosed. The amount of sieve material utilized is a fraction of that used in conventional portable devices. This dramatically reduces the volume, weight, and cost of the device. Innovations in valve configuration, moisture control, case and battery design, and replaceable sieve module are described. Patients with breathing disorders and others requiring medical oxygen are provided with a long lasting, low cost alternative to existing portable oxygen supply devices. |
FILED | Friday, November 08, 2019 |
APPL NO | 16/678026 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/0003 (20140204) A61M 16/20 (20130101) A61M 16/0063 (20140204) A61M 16/101 (20140204) Original (OR) Class A61M 16/105 (20130101) A61M 16/107 (20140204) A61M 16/0666 (20130101) A61M 16/0672 (20140204) A61M 16/0875 (20130101) A61M 16/1005 (20140204) A61M 2016/1025 (20130101) A61M 2202/0208 (20130101) A61M 2205/02 (20130101) A61M 2205/42 (20130101) A61M 2205/75 (20130101) A61M 2205/3327 (20130101) A61M 2205/3334 (20130101) A61M 2205/8206 (20130101) Separation B01D 53/02 (20130101) B01D 53/26 (20130101) B01D 53/0415 (20130101) B01D 53/0473 (20130101) B01D 2253/108 (20130101) B01D 2253/304 (20130101) B01D 2256/12 (20130101) B01D 2257/102 (20130101) B01D 2259/4533 (20130101) B01D 2259/4541 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/85938 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 11283658 | Roberts et al. |
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FUNDED BY |
|
APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
INVENTOR(S) | Megan J. Roberts (Boalsburg, Pennsylvania); Michael R. Gabrovsek (Boalsburg, Pennsylvania); Shawn Henderson (State College, Pennsylvania) |
ABSTRACT | Methods and apparatus for phased-based pre-carrier signal detection in a communication system are described. In embodiments, inphase and quadrature (IQ) data is generated from a received signal. A current phase delta value is determined from the IQ data and combined with existing phase delta value, such as an averaged phase delta value, which is compared with a threshold value to determine if a pre-carrier signal in the received signal has ended. |
FILED | Tuesday, October 15, 2019 |
APPL NO | 16/601968 |
ART UNIT | 2633 — Digital Communications |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 27/2273 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, March 22, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/details-patents-20220322.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page