FedInvent™ Patents
Patent Details for Tuesday, March 29, 2022
This page was updated on Wednesday, March 30, 2022 at 03:45 AM GMT
Department of Health and Human Services (HHS)
| US 11284788 | Maiorano et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Anthony Maiorano (Waltham, Massachusetts); Jeffrey C. Cerier (Franklin, Massachusetts) |
| ABSTRACT | In at least some aspects, an instrument port for introducing an instrument into a surgical site comprises: a port body having: an instrument channel extending through the port body; and a plurality of fluid flush channels each separate from one another and the instrument channel, each extending along a major portion of the port body and in fluid communication with the instrument channel; and a bulb comprising a bulb channel extending through the bulb, the bulb channel aligned with the instrument channel, wherein the bulb channel and instrument channel are configured to receive the instrument. |
| FILED | Friday, March 09, 2018 |
| APPL NO | 15/916844 |
| ART UNIT | 3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/05 (20130101) A61B 1/015 (20130101) A61B 1/018 (20130101) A61B 1/00066 (20130101) A61B 1/00094 (20130101) A61B 1/00096 (20130101) A61B 1/00101 (20130101) A61B 1/00119 (20130101) A61B 1/125 (20130101) A61B 1/126 (20130101) Original (OR) Class A61B 1/00128 (20130101) A61B 1/0676 (20130101) A61B 17/3415 (20130101) A61B 17/3421 (20130101) A61B 17/3498 (20130101) A61B 2017/00243 (20130101) A61B 2017/3445 (20130101) A61B 2217/005 (20130101) A61B 2217/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11284792 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Ruikang K. Wang (Seattle, Washington); Anqi Zhang (Seattle, Washington); Qinqin Zhang (Seattle, Washington) |
| ABSTRACT | Systems and methods for enhancing quality of a flow image of a sample of a subject are provided. The method comprises acquiring a first flow image from a plurality of first OMAG scans of the sample, and acquiring a structure image from a second OMAG scan of the sample. Data based on pixel intensity values from the flow image and pixel intensity values from the structure image are then plotted onto a graph and from the graph, may be differentiated into a first data group representing static structure signals and a second data group representing flow signals. The method then includes suppressing pixels in the flow image corresponding to the first data group. The flow signal may also be multiplied by a weighting factor to suppress artifacts in the image. |
| FILED | Monday, March 07, 2016 |
| APPL NO | 15/552437 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/14 (20130101) A61B 3/0025 (20130101) A61B 3/102 (20130101) Original (OR) Class A61B 3/1241 (20130101) A61B 5/0066 (20130101) A61B 5/0261 (20130101) A61B 5/489 (20130101) A61B 2576/02 (20130101) Image Data Processing or Generation, in General G06T 5/005 (20130101) G06T 2207/10101 (20130101) G06T 2207/20072 (20130101) G06T 2207/20076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11284823 | Hobbs et al. |
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| FUNDED BY |
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| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Theodore Hobbs (Portland, Oregon); Ravikant Samatham (Portland, Oregon); Steven L. Jacques (Portland, Oregon) |
| ABSTRACT | Disclosed are a method, device and system for determining total circulating blood volume (BV) using a minimally invasive technique. |
| FILED | Thursday, December 27, 2018 |
| APPL NO | 16/233488 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0071 (20130101) A61B 5/0075 (20130101) A61B 5/0261 (20130101) A61B 5/0275 (20130101) A61B 5/1459 (20130101) A61B 5/02028 (20130101) A61B 5/6831 (20130101) A61B 5/6832 (20130101) A61B 5/6852 (20130101) A61B 5/14535 (20130101) A61B 5/14552 (20130101) A61B 5/14556 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11284838 | Howard et al. |
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| FUNDED BY |
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| APPLICANT(S) | George Mason University (Fairfax, Virginia) |
| ASSIGNEE(S) | George Mason University Research Foundation, Inc. (Fairfax, Virginia) |
| INVENTOR(S) | Marissa A. Howard (Richmond, Virginia); Lance A. Liotta (Bethesda, Maryland); Rachel Naidich (Fairfax, Virginia); Matthew Luu Trang (Nokesville, Virginia); Ish Sethi (Chantilly, Virginia); Rebecca Woodhouse (Oakton, Virginia); Kshamata Neupane (Haymarket, Virginia) |
| ABSTRACT | A wearable device measures, tracks, and monitors a wearer's physical physiological conditions during a rehabilitation period. Metrics such as temperature, patellar shifting, limb circumference, and acceleration may be collected. Changes in monitored conditions may be assessed for detecting medical abnormalities which require specialized attention, including for example embolisms or infections. A networked communication system and various user interfaces may be used for medical support personnel and patients alike to stay updated with the patient's rehabilitation progress and to make adjustments in a patient's individual rehabilitation program. |
| FILED | Wednesday, October 24, 2018 |
| APPL NO | 16/169295 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/015 (20130101) A61B 5/0024 (20130101) A61B 5/0048 (20130101) A61B 5/0053 (20130101) A61B 5/112 (20130101) A61B 5/746 (20130101) A61B 5/1107 (20130101) A61B 5/1114 (20130101) A61B 5/1126 (20130101) A61B 5/4519 (20130101) A61B 5/4528 (20130101) A61B 5/4585 (20130101) A61B 5/4848 (20130101) A61B 5/6824 (20130101) A61B 5/6828 (20130101) Original (OR) Class A61B 5/6829 (20130101) A61B 5/7275 (20130101) A61B 5/7465 (20130101) A61B 2503/08 (20130101) A61B 2503/10 (20130101) A61B 2505/09 (20130101) A61B 2562/0219 (20130101) A61B 2562/0247 (20130101) A61B 2562/0261 (20130101) A61B 2562/0271 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 2230/08 (20130101) A61H 2230/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11284851 | Madabhushi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Thomas Atta-Fosu (Cleveland Heights, Ohio); Soumya Ghose (Niskayuna, New York) |
| ABSTRACT | Embodiments access a set of radiological images acquired from a population of subjects, where a member of the set of radiological images includes a left atrium (LA) region; construct a statistical shape differential atlas from the images; generate a template LA model from the statistical shape differential atlas, where the template LA model includes a site of interest (SOI); acquire a pre-ablation radiological image of a region of tissue in a patient demonstrating atrial fibrillation (AF) pathology; generate a patient LA model from the pre-ablation image; compute a deformation field that registers the SOI to the patient LA model using deformable registration; compute a patient feature vector based on the deformation field; generate an AF probability score for the patient based on the feature vector; generate a classification of the patient based, at least in part, on the AF probability score; and display the classification or the AF probability score. |
| FILED | Friday, March 22, 2019 |
| APPL NO | 16/361421 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/361 (20210101) A61B 6/032 (20130101) A61B 6/54 (20130101) A61B 6/463 (20130101) A61B 6/469 (20130101) A61B 6/503 (20130101) Original (OR) Class A61B 6/5217 (20130101) A61B 2018/00351 (20130101) A61B 2018/00577 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 2207/30048 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 30/40 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285106 | Thaxton et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | C. Shad Thaxton (Chicago, Illinois); Chad A. Mirkin (Wilmette, Illinois); Kaylin M. McMahon (Chicago, Illinois); Sushant Tripathy (Evanston, Illinois); Raja Kannan Mutharasan (Chicago, Illinois); David M. Leander (St. Louis, Missouri); Andrea Luthi (Evanston, Illinois) |
| ABSTRACT | Articles, compositions, kits, and methods relating to nanostructures, including synthetic nanostructures, are provided. Certain embodiments described herein include structures having a core-shell type arrangement; for instance, a nanostructure core may surrounded by a shell including a material, such as a lipid bilayer, and may include other components such as oligonucleotides. In some embodiments, the structures, when introduced into a subject, can be used to deliver nucleic acids and/or can regulate gene expression. Accordingly, the structures described herein may be used to diagnose, prevent, treat or manage certain diseases or bodily conditions. In some cases, the structures are both a therapeutic agent and a diagnostic agent. |
| FILED | Monday, April 15, 2019 |
| APPL NO | 16/384749 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) Original (OR) Class A61K 9/1271 (20130101) A61K 9/5115 (20130101) A61K 9/5123 (20130101) A61K 31/7088 (20130101) A61K 47/544 (20170801) A61K 47/554 (20170801) A61K 47/6917 (20170801) A61K 47/6923 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) C12N 15/111 (20130101) C12N 2310/113 (20130101) C12N 2310/3515 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285137 | Kolesnick et al. |
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| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan-Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | Richard Kolesnick (New York, New York); Adriana Haimovitz-Friedman (New York, New York); Evis Sala (New York, New York); Zvi Fuks (New York, New York) |
| ABSTRACT | Disclosed is a method for enhancing tumor response to chemotherapy, the method comprising administering a short-acting anti-angiogenic agent (AAA) capable of activating ASMase to a subject afflicted with a solid tumor, and thereby creating a time interval of increased susceptibility of said tumor to one or more chemotherapeutic agents, followed by administration of at least one chemotherapeutic agent within the interval. The interval can be defined in terms of a short-duration activation of ASMase signaling by the AAA. Disclosed are also methods for predicting the tumor response in a patient afflicted with a solid tumor to a chemotherapeutic agent, using as an indicator of the response ASMase level or activity (or ceramide level) in the patient following the administration of the chemotherapeutic agent to the patient, or dynamic IVIM based DW-MRI to measure perfusion alterations following administration of the chemotherapeutic agent. |
| FILED | Thursday, July 18, 2019 |
| APPL NO | 16/516235 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/337 (20130101) A61K 31/404 (20130101) A61K 31/404 (20130101) A61K 31/4439 (20130101) Original (OR) Class A61K 31/4439 (20130101) A61K 31/7048 (20130101) A61K 31/7048 (20130101) A61K 31/7068 (20130101) A61K 31/7068 (20130101) A61K 33/24 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57488 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285142 | Calakos et al. |
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| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY DEPARMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Duke University (Durham, North Carolina) |
| INVENTOR(S) | Nicole Calakos (Chapel Hill, North Carolina); Zachary F. Caffall (Durham, North Carolina); Joseph Rittiner (Durham, North Carolina); Min Shen (Boyds, Maryland); Jennifer T. Fox (Rockville, Maryland); Zhuyin Li (Wallingford, Connecticut) |
| ABSTRACT | The present disclosure provides methods and compositions for the treatment, identification, diagnosis, and prognosis of dystonia, or dystonia related disorders. |
| FILED | Thursday, September 29, 2016 |
| APPL NO | 15/764320 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/47 (20130101) Original (OR) Class A61K 31/427 (20130101) A61K 31/472 (20130101) A61K 31/497 (20130101) A61K 31/513 (20130101) A61K 31/4706 (20130101) A61K 31/4725 (20130101) A61K 38/05 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/14 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6883 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2800/52 (20130101) G01N 2800/2835 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285144 | Sundberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts); DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Thomas Sundberg (Cambridge, Massachusetts); Alykhan Shamji (Cambridge, Massachusetts); Ramnik Xavier (Boston, Massachusetts); Liv Johannessen (Boston, Massachusetts); Nathanael Gray (Boston, Massachusetts); Bernard Khor (Boston, Massachusetts); Jose Perez (Cambridge, Massachusetts) |
| ABSTRACT | A method for treating inflammation and/or autoimmune diseases comprises administering to a subject in need thereof, a composition comprising a CDK8 inhibitor. In another aspect, a method for increasing IL-10 production comprises administering to a subject in need thereof a CDK8 inhibitor. In another aspect, a method for enhancing Treg cell differentiation, comprising administering a composition comprising a CDK8 inhibitor. In certain example embodiments, the subject suffers from an inflammatory bowel disease. In certain other example embodiments, the subject requires immunosuppression to prevent rejection following a transplantation procedure. |
| FILED | Thursday, August 03, 2017 |
| APPL NO | 16/323227 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/58 (20130101) A61K 31/407 (20130101) A61K 31/444 (20130101) A61K 31/517 (20130101) A61K 31/4545 (20130101) A61K 31/4709 (20130101) Original (OR) Class A61K 31/4725 (20130101) A61K 31/4985 (20130101) A61K 31/5025 (20130101) A61K 35/17 (20130101) A61K 38/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6869 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285147 | Dutta |
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| FUNDED BY |
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| APPLICANT(S) | WAYNE STATE UNIVERSITY (Detroit, Michigan) |
| ASSIGNEE(S) | Wayne State University (Detroit, Michigan) |
| INVENTOR(S) | Aloke K. Dutta (Troy, Michigan) |
| ABSTRACT | A compound having formula I is useful for treating a neurodegenerative disease: or a pharmaceutically acceptable salt or ester thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8 are each independently hydroxyl, C1-4 alkyl, C1-4 alkoxyl, C1-8 alkyl, C2-8 alkenyl, C2-8 alkynyl, C4-8, are specified substituents. |
| FILED | Friday, September 06, 2019 |
| APPL NO | 16/562942 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/135 (20130101) A61K 31/427 (20130101) A61K 31/495 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285149 | Frank et al. |
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| FUNDED BY |
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| APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | David Frank (Lexington, Massachusetts); Darwin Ye (Boston, Massachusetts) |
| ABSTRACT | The present invention relates to a combination of a signal transducer and activator of transcription 3 (STAT3) activity inhibitor; and an immune checkpoint inhibitor for use in treating or preventing the hyperproliferative disorder in a subject. Preferably, the STA3 activity inhibitor is pyrimethamine or atovaquone, and the immune checkpoint inhibitor is an anti-PD1 antibody. Preferably, the hyperproliferative disorder is a glioma or a glioblastoma. |
| FILED | Friday, July 27, 2018 |
| APPL NO | 16/633780 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 31/122 (20130101) A61K 31/505 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Peptides C07K 16/2818 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285154 | Habib |
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| FUNDED BY |
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| APPLICANT(S) | United States Government as Represented by The Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Amyn Aziz Habib (Dallas, Texas) |
| ABSTRACT | Provided herein are methods and pharmaceutical compositions for treating cancer, in a patient in need thereof, said method comprising administering to said patient an effective amount of an EGFR inhibitor and a TNF inhibitor. |
| FILED | Thursday, March 29, 2018 |
| APPL NO | 15/940802 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/17 (20130101) A61K 31/277 (20130101) A61K 31/277 (20130101) A61K 31/416 (20130101) A61K 31/416 (20130101) A61K 31/454 (20130101) A61K 31/454 (20130101) A61K 31/498 (20130101) A61K 31/498 (20130101) A61K 31/502 (20130101) A61K 31/502 (20130101) A61K 31/517 (20130101) Original (OR) Class A61K 31/517 (20130101) A61K 31/573 (20130101) A61K 31/713 (20130101) A61K 31/713 (20130101) A61K 31/4178 (20130101) A61K 31/4178 (20130101) A61K 31/4439 (20130101) A61K 31/4439 (20130101) A61K 31/4985 (20130101) A61K 31/4985 (20130101) A61K 38/1793 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/241 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285162 | Ashcraft et al. |
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| FUNDED BY |
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| APPLICANT(S) | BioMimetix JV, LLC (Englewood, Colorado); Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | BioMimetix JV, LLC (Englewood, Colorado); Duke University (Durham, North Carolina) |
| INVENTOR(S) | Kathleen Ashcraft (Durham, North Carolina); Mark Dewhirst (Chapel Hill, North Carolina); Ines Batinic-Haberle (Durham, North Carolina); James D. Crapo (Englewood, Colorado) |
| ABSTRACT | Described herein are methods, compositions, and kits for treating and/or preventing in a subject one or more side effects associated with radiation and/or chemotherapy exposure, including methods, compositions and kits that include an active agent at a low dose. In some embodiments, methods, compositions, and kits for treating and/or preventing tissue damage in a subject are provided, including methods, compositions and kits that include an active agent at a low dose. |
| FILED | Wednesday, April 04, 2018 |
| APPL NO | 16/500490 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/555 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285165 | DeNardo et al. |
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| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Sally J. DeNardo (El Macero, California); Gerald L. DeNardo (El Macero, California); Rodney L. Balhorn (Livermore, California) |
| ABSTRACT | This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use of antibodies. SHALs typically comprise a multiplicity of ligands that each bind different region son the target molecule. The ligands are joined directly or through a linker thereby forming a polydentate moiety that typically binds the target molecule with high selectivity and avidity. |
| FILED | Wednesday, April 08, 2020 |
| APPL NO | 16/843783 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/675 (20130101) Original (OR) Class A61K 47/55 (20170801) A61K 47/60 (20170801) A61K 47/64 (20170801) A61K 47/545 (20170801) A61K 47/645 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285169 | Roberts et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | David D. Roberts (Bethesda, Maryland); David R. Soto Pantoja (Rockville, Maryland) |
| ABSTRACT | Methods of reducing cytotoxicity of a chemotherapeutic agent to non-cancer cells by administering to a subject with cancer an effective amount of an agent that inhibits CD47 signaling and a DNA damaging agent, such as an anthracycline, topoisomerase inhibitor, or nucleotide synthesis inhibitor, are provided. Example disclosed methods reduce cardiotoxicity. In one example, the methods include administering to a subject with cancer an effective amount of a CD47 antisense morpholino oligonucleotide and an anthracycline such as doxorubicin. Methods of increasing cytotoxicity of a chemotherapeutic agent in cancer cells by administering to a subject with a tumor an effective amount of an agent that inhibits CD47 signaling and a DNA damaging agent such as an anthracycline, topoisomerase inhibitor, or nucleotide synthesis inhibitor, are also provided. In some embodiments, the inhibitor of CD47 signaling is administered to the subject before, during, or after the administration of the DNA damaging agent. |
| FILED | Thursday, March 13, 2014 |
| APPL NO | 14/775428 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/52 (20130101) A61K 31/52 (20130101) A61K 31/65 (20130101) A61K 31/65 (20130101) A61K 31/137 (20130101) A61K 31/137 (20130101) A61K 31/351 (20130101) A61K 31/365 (20130101) A61K 31/365 (20130101) A61K 31/437 (20130101) A61K 31/437 (20130101) A61K 31/505 (20130101) A61K 31/505 (20130101) A61K 31/513 (20130101) A61K 31/704 (20130101) A61K 31/704 (20130101) A61K 31/706 (20130101) A61K 31/706 (20130101) A61K 31/711 (20130101) A61K 31/711 (20130101) A61K 31/712 (20130101) A61K 31/712 (20130101) A61K 31/713 (20130101) Original (OR) Class A61K 31/787 (20130101) A61K 31/7064 (20130101) A61K 31/7064 (20130101) A61K 39/39558 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 39/00 (20180101) Peptides C07K 16/2803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285193 | Khalili et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Temple University of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Temple University of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Kamel Khalili (Bala Cynwyd, Pennsylvania); Wenhui Hu (Cherry Hill, New Jersey) |
| ABSTRACT | A method of treating a subject at risk for having a virus infection, by administering to the subject a prophylactically effective amount of a composition comprising a vector encoding a CRISPR-associated endonuclease and at least two guide RNAs, wherein the guide RNAs are complementary to two target sequences spanning from the 5′- to 3′-LTRs of the sequence in the virus, and preventing a retroviral infection. |
| FILED | Monday, January 29, 2018 |
| APPL NO | 15/882207 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0034 (20130101) A61K 35/12 (20130101) A61K 38/465 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 48/00 (20130101) A61K 48/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/22 (20130101) C12N 15/111 (20130101) C12N 2310/20 (20170501) C12N 2320/30 (20130101) C12N 2740/16063 (20130101) Enzymes C12Y 301/21 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285197 | Jaffee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Elizabeth A. Jaffee (Lutherville, Maryland); Tzyy-Choou Wu (Stevenson, Maryland); Chien-Fu Hung (Timonium, Maryland); Ralph Hruban (Baltimore, Maryland) |
| ABSTRACT | Mesothelin can be used as an immunotherapeutic target. It induces a cytolytic T cell response. Portions of mesothelin which induce such responses are identified. Vaccines can be either polynucleotide- or polypeptide-based. Carriers for raising a cytolytic T cell response include bacteria and viruses. A mouse model for testing vaccines and other anti-tumor therapeutics and prophylactics comprises a strongly mesothelin-expressing, transformed peritoneal cell line. |
| FILED | Tuesday, July 02, 2019 |
| APPL NO | 16/460993 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2267/0331 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 39/0208 (20130101) Original (OR) Class A61K 39/001168 (20180801) A61K 2039/52 (20130101) A61K 2039/53 (20130101) A61K 2039/57 (20130101) A61K 2039/505 (20130101) A61K 2039/522 (20130101) A61K 2039/523 (20130101) A61K 2039/5154 (20130101) A61K 2039/6031 (20130101) A61K 2039/55511 (20130101) A61K 2039/55522 (20130101) Peptides C07K 7/06 (20130101) C07K 14/4748 (20130101) C07K 16/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/74 (20130101) C12N 15/8509 (20130101) C12N 2710/16522 (20130101) C12N 2740/13043 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285209 | Deng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | Liang Deng (New York, New York); Stewart Shuman (New York, New York); Jedd Wolchok (New York, New York); Taha Merghoub (New York, New York); Weiyi Wang (New York, New York); Peihong Dai (New York, New York); Ning Yang (New York, New York) |
| ABSTRACT | The present invention relates generally to the fields of oncology, virology and immunotherapy. More particularly, it concerns the use of a recombinant modified vaccinia Ankara (MVA) virus comprising an MVA harboring a human Fms-like tyrosine kinase 3 ligand (hFlt3L) (MVA-hFtl3L). The foregoing vaccinia Ankara (MVA) virus can be delivered to tumor cells of a subject afflicted with a malignant solid tumor, to treat the tumor. In a related aspect, the present disclosure concerns a recombinant modified vaccinia Ankara virus with deletion of vaccinia virulence factor E3 (MV At.E3L) modified to express human Fms-like 5 tyrosine kinase 3 ligand (hFlt3L) isolated, suitable for use as an immunotherapeutic agent against a malignant solid tumor. |
| FILED | Friday, April 10, 2020 |
| APPL NO | 16/845809 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/768 (20130101) A61K 39/0011 (20130101) A61K 39/3955 (20130101) Original (OR) Class A61K 39/3955 (20130101) A61K 2039/505 (20130101) A61K 2039/55522 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/521 (20130101) C07K 16/2818 (20130101) C07K 16/2827 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2710/24032 (20130101) C12N 2710/24121 (20130101) C12N 2710/24132 (20130101) C12N 2710/24143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285211 | Fahmy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Tarek Fahmy (Middlefield, Connecticut); Albert Sinusas (Guilford, Connecticut); Jung Seok Lee (New Haven, Connecticut); Dongin Kim (Glastonbury, Connecticut); Anthony Mathur (London, United Kingdom); John Martin (London, United Kingdom) |
| ABSTRACT | It has been discovered that iron-platinum ferromagnetic particles can be dispersed in a polymer and coated into or onto, or directly linked to or embedded on to, medical devices and magnetized. The magnetized devices are used to attract, capture, and/or retain magnetically labeled cells on the surface of the device in vivo. The magnetic particles have an iron/platinum core. Annealing the Fe/Pt particle is very important for introducing a L10 interior crystalline phase. The Fe:Pt molar ratio for creation of the crystal phase is important and a molar range of 1.2-3.0 Fe to Pt (molar precursors, i.e. starting compounds) is desired for magnetization. The magnetic force as a whole can be measured with a “Super Conducting Quantum Interference Device”, which is a sensitive magnetometer. The overall magnetic force is in the range from 0.1 to 2.0 Tesla. |
| FILED | Wednesday, April 01, 2015 |
| APPL NO | 15/563398 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/82 (20130101) A61F 2210/009 (20130101) A61F 2210/0076 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/44 (20130101) A61K 35/545 (20130101) A61K 41/0052 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/06 (20130101) A61L 27/18 (20130101) A61L 27/025 (20130101) A61L 27/34 (20130101) A61L 27/042 (20130101) A61L 27/047 (20130101) A61L 27/58 (20130101) A61L 27/306 (20130101) A61L 31/06 (20130101) A61L 31/10 (20130101) A61L 31/022 (20130101) A61L 31/028 (20130101) A61L 31/088 (20130101) A61L 31/148 (20130101) A61L 2400/18 (20130101) A61L 2420/02 (20130101) A61L 2420/06 (20130101) A61L 2420/08 (20130101) A61L 2430/20 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 2/002 (20130101) A61N 2/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285212 | Davis et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute Of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Mark E. Davis (Pasadena, California); Han Han (Belmont, California) |
| ABSTRACT | Described herein are carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a nitroboronic boronic acid and a linkage cleavable under reducing conditions, configured to present the polymer containing the nitroboronic acid to an environment external to the nanoparticle. Targeted versions of the described nanoparticles are also described, as are related compositions, methods and systems. |
| FILED | Monday, November 26, 2018 |
| APPL NO | 16/200095 |
| ART UNIT | 1699 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5161 (20130101) A61K 31/337 (20130101) A61K 31/337 (20130101) A61K 31/727 (20130101) A61K 31/727 (20130101) A61K 31/4745 (20130101) A61K 31/4745 (20130101) A61K 45/06 (20130101) Original (OR) Class A61K 47/60 (20170801) A61K 47/6935 (20170801) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285227 | Babich et al. |
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| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | John W. Babich (New York, New York); James M. Kelly (New York, New York); Alejandro Amor-Coarasa (New York, New York); Shashikanth Ponnala (New York, New York) |
| ABSTRACT | The present technology provides compounds, as well as compositions including such compounds, useful for imaging and/or treatment of a glioma, a breast cancer, an adrenal cortical cancer, a cervical carcinoma, a vulvar carcinoma, an endometrial carcinoma, a primary ovarian carcinoma, a metastatic ovarian carcinoma, a non-small cell lung cancer, a small cell lung cancer, a bladder cancer, a colon cancer, a primary, gastric adenocarcinoma, a primary colorectal adenocarcinoma, a renal cell carcinoma, and/or a prostate cancer. The compounds are represented by the following formula: (I) or a pharmaceutically acceptable salt thereof. |
| FILED | Thursday, April 05, 2018 |
| APPL NO | 16/500380 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 51/065 (20130101) Original (OR) Class A61K 51/0402 (20130101) A61K 51/0497 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285318 | Tai |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Changfeng Tai (Wexford, Pennsylvania) |
| ABSTRACT | Provided herein are methods for treating underactive bladder, urinary retention, detrusor-sphincter dyssynergia after spinal cord injury, constipation, and/or infrequent bowel movements including the step of applying electrical stimulation to one or more peripheral nerves. |
| FILED | Wednesday, May 02, 2018 |
| APPL NO | 16/609883 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0456 (20130101) A61N 1/36007 (20130101) Original (OR) Class A61N 1/36034 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285325 | Danilov et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yuri P. Danilov (Middleton, Wisconsin); Mitchell E. Tyler (Madison, Wisconsin); Kurt A. Kaczmarek (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yuri P. Danilov (Middleton, Wisconsin); Mitchell E. Tyler (Madison, Wisconsin); Kurt A. Kaczmarek (Madison, Wisconsin) |
| ABSTRACT | In a patient suffering from neural impairment, stimulation is provided to sensory surfaces of the face and/or neck, or more generally to areas of the body that stimulate the trigeminal nerve, while performing an activity intended to stimulate a brain function to be rehabilitated. The simulation may then be continued after the performance of the activity has ceased. It has been found that the patient's performance of the activity is then improved after stimulation has ceased. Moreover, it tends to improve to a greater extent, and/or for a longer time, when the post-activity stimulation is applied, as compared to when post activity stimulation is not applied. |
| FILED | Monday, June 24, 2019 |
| APPL NO | 16/450915 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 21/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/361 (20130101) A61N 1/0456 (20130101) A61N 1/0476 (20130101) A61N 1/0492 (20130101) A61N 1/0526 (20130101) A61N 1/0548 (20130101) A61N 1/36014 (20130101) A61N 1/36025 (20130101) A61N 1/36067 (20130101) A61N 1/36078 (20130101) A61N 1/36082 (20130101) A61N 1/36092 (20130101) A61N 1/36096 (20130101) A61N 1/36103 (20130101) Original (OR) Class Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 19/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285337 | Vartanian et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Garen V. Vartanian (Ann Arbor, Michigan); Kwoon Y. Wong (Ann Arbor, Michigan); Pei-Cheng Ku (Ann Arbor, Michigan); Scott A. Almburg (Redford Township, Michigan) |
| ABSTRACT | A light source and a method of generating a light using the light source is disclosed. The light source is configured to produce a plurality of distinct colors in generating the light, one of the distinct colors falling within a blue spectral light band. A light controller modulates the spectral light produced by the plurality of distinct colors. The modulation provides melanopsin contrast in order to increase melanopsin responsiveness of a subject exposed to the generated light and maintains the color temperature, color quality, and color constancy experienced by the subject in a lit viewing environment within an acceptable range. |
| FILED | Monday, July 24, 2017 |
| APPL NO | 15/658338 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0618 (20130101) Original (OR) Class A61N 5/0622 (20130101) A61N 2005/0626 (20130101) A61N 2005/0652 (20130101) A61N 2005/0663 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285340 | Larkin et al. |
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| FUNDED BY |
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| APPLICANT(S) | RefleXion Medical, Inc. (Hayward, California) |
| ASSIGNEE(S) | RefleXion Medical, Inc. (Hayward, California) |
| INVENTOR(S) | David Larkin (Menlo Park, California); William Knapp (El Granada, California); Layton Hale (Castro Valley, California) |
| ABSTRACT | Described herein are multi-leaf collimators that comprise leaf drive mechanisms. The leaf drive mechanisms can be used in binary multi-leaf collimators used in emission-guided radiation therapy. One variation of a multi-leaf collimator comprises a pneumatics-based leaf drive mechanism. Another variation of a multi-leaf collimator comprises a spring-based leaf drive mechanism having a spring resonator. |
| FILED | Thursday, November 07, 2019 |
| APPL NO | 16/677200 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1045 (20130101) Original (OR) Class A61N 2005/1074 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285478 | Hung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Combinati Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Combinati Incorporated (Carlsbad, California) |
| INVENTOR(S) | Ju-Sung Hung (Palo Alto, California); Andrew Zayac (San Leandro, California); Megan Dueck (Brisbane, California) |
| ABSTRACT | In some aspects, the present disclose provides methods for amplifying and quantifying nucleic acids. Methods for amplifying and quantifying nucleic acids comprise isolating a sample comprising nucleic acid molecules into a plurality of microchambers, performing a polymerase chain reaction on the plurality of microchambers, and analyzing the results of the polymerase chain reaction. In some aspects, the present disclosure provides devices consistent with the methods herein. |
| FILED | Friday, October 13, 2017 |
| APPL NO | 15/783743 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Original (OR) Class B01L 7/52 (20130101) B01L 2200/0605 (20130101) B01L 2300/18 (20130101) B01L 2300/0609 (20130101) B01L 2300/0851 (20130101) B01L 2300/0864 (20130101) B01L 2400/049 (20130101) B01L 2400/0487 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/686 (20130101) C12Q 2563/159 (20130101) C12Q 2565/629 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286182 | Ball |
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| FUNDED BY |
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| APPLICANT(S) | OXYTEC LLC (Newton, Massachusetts) |
| ASSIGNEE(S) | OXYTEC LLC (Newton, Massachusetts) |
| INVENTOR(S) | Raymond G. Ball (Newton, Massachusetts) |
| ABSTRACT | Disclosed are methods, apparatuses and systems for the remediation of contaminated soils, groundwater, water, and/or waste using a combination of reagents. The disclosed methods may be used to treat various recalcitrant halogenated substances, such as perfluoroalkyls and polyfluoroalkyls. Particular combinations of reagents that may be used in the disclosed methods include but are not limited to: (1) persulfate, oxygen and ozone; (2) persulfate, salt, oxygen and ozone; (3) persulfate, phosphate, and/or oxygen; (4) persulfate, phosphate, oxygen and ozone; (5) persulfate, phosphate, salt and oxygen (6) persulfate, phosphate, salt, oxygen and ozone; (7) oxygen and salt; and (8) air and salt. The disclosed methods may enhance destruction of organic contaminants in the liquid phase and may also control the rate of aerosol or foam formation relative to the rate of chemical oxidation and/or reduction/transfer. |
| FILED | Monday, March 29, 2021 |
| APPL NO | 17/216089 |
| ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Reclamation of Contaminated Soil B09C 1/002 (20130101) B09C 1/06 (20130101) B09C 1/08 (20130101) B09C 2101/00 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/32 (20130101) C02F 1/70 (20130101) C02F 1/78 (20130101) C02F 1/722 (20130101) Original (OR) Class C02F 1/725 (20130101) C02F 1/727 (20130101) C02F 2101/34 (20130101) C02F 2101/36 (20130101) C02F 2101/305 (20130101) C02F 2101/306 (20130101) C02F 2101/322 (20130101) C02F 2101/327 (20130101) C02F 2101/363 (20130101) C02F 2103/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286251 | Sadeghi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Mehran Sadeghi (Bethany, Connecticut); Yunpeng Ye (Staten Island, New York); Hye-Yeong Kim (Hamden, Connecticut); Henry(Yiyun) Huang (Madison, Connecticut); Jakub Toczek (New Haven, Connecticut) |
| ABSTRACT | The present invention provides certain compounds, or salts or solvates thereof, which can be used as matrix metalloproteinase-targeted inhibitors or imaging agents. |
| FILED | Friday, April 07, 2017 |
| APPL NO | 16/088868 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/044 (20130101) Heterocyclic Compounds C07D 273/01 (20130101) C07D 413/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286256 | Fuller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alkermes, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | Alkermes, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Nathan Oliver Fuller (Arlington, Massachusetts); John A. Lowe, III (Stonington, Connecticut) |
| ABSTRACT | Provided herein are compounds and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of conditions associated with inhibition of HDAC (e.g,. HDAC2). |
| FILED | Thursday, May 21, 2020 |
| APPL NO | 16/880075 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/519 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286270 | Hecker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Qpex Biopharma, Inc. (San Diego, California) |
| ASSIGNEE(S) | Qpex Biopharma, Inc. (San Diego, California) |
| INVENTOR(S) | Scott J. Hecker (Del Mar, California); Serge Henri Boyer (San Diego, California); Hubertus J. A. Dielemans (Beek, Netherlands); Angela Gonzalez de Castro (Maastricht, Netherlands); Andreas H. M. de Vries (Maastricht, Netherlands); Laurent Lefort (Maastricht, Netherlands) |
| ABSTRACT | Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the method of use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents, for example, β-lactamase inhibitors (BLIs). |
| FILED | Wednesday, October 10, 2018 |
| APPL NO | 16/755138 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/44 (20130101) B01J 23/755 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286279 | Franco |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alessandra Franco (San Diego, California) |
| ABSTRACT | Provided are compositions, including isolated, synthetic or recombinant peptides for: expanding regulatory T cells (Treg) populations; for treating or ameliorating a vascular inflammation, and Kawasaki disease (KD) or a pediatric acute vasculitis of the coronary arteries, including vascular coronary abnormalities, and acute or chronic vascular inflammatory abnormalities, and method for making and using them. Provided are immunotherapies for promoting expansion of natural, Treg to establish, or re-establish, vascular homeostasis; or, for ameliorating: a disease or condition associated with an autoimmune disease or condition; as immune-mediated vascular disorder; a disease or condition treated with intravenous immunoglobulin (IVIG) therapy; a vascular coronary abnormality; an acute or a chronic vasculitis; an autoimmune vasculitis; Kawasaki disease (KD) or a pediatric acute vasculitis of the coronary arteries; atherosclerosis; preventing miscarriage in autoimmune women; rheumatoid arthritis or Juvenile Idiopathic Arthritis; a neoplastic hematological disorder, or a leukemia. |
| FILED | Monday, August 10, 2020 |
| APPL NO | 16/989816 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 9/127 (20130101) A61K 38/00 (20130101) A61K 39/0005 (20130101) A61K 39/0008 (20130101) A61K 2039/545 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286287 | Deslouches et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Berthony Deslouches (Pittsburgh, Pennsylvania); Yuanpu Di (Wexford, Pennsylvania) |
| ABSTRACT | This disclosure is directed to compositions comprised of antimicrobial peptides (AMPs) having an alpha helical structure wherein one side is highly hydrophobic. Representative sequences of the antimicrobial peptides include ILKKWWββαβGLLGβLLGαVββVIKβLββI (SEQ ID No. 2), LKKWWKβαKGLLGGLLGKVββVIK (SEQ ID No. 12), and αKKααKKαKGαLGGLαGK (SEQ ID No. 18). Additional embodiments disclose methods for treating a microbial infection; reducing biofilm; decreasing inflammation; and treating infectious diseases, COPD, asthma, pulmonary fibrosis, cystic fibrosis, rhinosinusitis, septicemia, RSV, TB or cancer; in a subject in need thereof comprising administering to the subject a therapeutic amount of an antimicrobial peptide. |
| FILED | Tuesday, November 21, 2017 |
| APPL NO | 16/462586 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/4723 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286299 | Xue et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Trustees of Darthmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Vincent Xue (Somerville, Massachusetts); Justin Michael Jenson (Cambridge, Massachusetts); Amy E. Keating (Arlington, Massachusetts); Jianfu Zhou (White River Junction, Vermont); Gevorg Grigoryan (Hanover, New Hampshire) |
| ABSTRACT | Provided herein are peptides selective for combinations of Mcl-1/Bfl-1/Bcl-xL. Also provided are compositions containing these polypeptides and methods of using such peptides in the treatment of cancer that include administering to a subject one of the polypeptides. |
| FILED | Tuesday, September 17, 2019 |
| APPL NO | 16/573881 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 16/28 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286301 | Wernig et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Gerlinde Wernig (Stanford, California); Irving L. Weissman (Stanford, California) |
| ABSTRACT | Compositions and methods are provided for treating fibrosis in a mammal by administering a therapeutic dose of a pharmaceutical composition. |
| FILED | Wednesday, February 28, 2018 |
| APPL NO | 16/487051 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1774 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) A61P 11/00 (20180101) Peptides C07K 16/2803 (20130101) Original (OR) Class C07K 16/2896 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286461 | Visconti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Pablo E. Visconti (Amherst, Massachusetts); Felipe Navarrete (Hadley, Massachusetts) |
| ABSTRACT | Methods for improving the functionality and/or fertility of sperm, for example, by enhancing motility and/or extending the lifespan of sperm by subjecting the isolated sperm to a starvation protocol and/or ionophore are provided. Such methods may be used in, for example, artificial insemination to reduce the number of sperm needed for insemination and to improve conception rates. |
| FILED | Friday, March 31, 2017 |
| APPL NO | 16/089862 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0205 (20130101) Diagnosis; Surgery; Identification A61B 17/43 (20130101) A61B 17/435 (20130101) Veterinary Instruments, Implements, Tools, or Methods A61D 19/02 (20130101) A61D 19/04 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/061 (20130101) C12N 5/0604 (20130101) Original (OR) Class C12N 15/00 (20130101) C12N 2501/998 (20130101) C12N 2501/999 (20130101) C12N 2517/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286462 | Nishimune et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Hiroshi Nishimune (Kansas City, Missouri); Richard Barohn (Kansas City, Missouri); Buddhadeb Dawn (Mission Hills, Kansas); Yomna Badawi (Leawood, Kansas); James W. Mitchell (Overland Park, Kansas); Rupal Soder (Prairie Village, Kansas) |
| ABSTRACT | Embodiments of the present disclosure relate generally to the production of therapeutic mesenchymal stem cells (MSCs). More particularly, the present disclosure relates to the use of cell culture compositions and methods for generating MSCs that secrete neurotrophic factors and synaptic organizing agents for the treatment of neurodegenerative diseases such as Amyotrophic Lateral Sclerosis (ALS). As such, the present disclosure addresses the need for establishing a reliable source of therapeutic stem cells useful for the treatment of neurodegenerative diseases. |
| FILED | Friday, September 14, 2018 |
| APPL NO | 16/647345 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/51 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0668 (20130101) Original (OR) Class C12N 2500/32 (20130101) C12N 2501/10 (20130101) C12N 2501/13 (20130101) C12N 2501/105 (20130101) C12N 2501/115 (20130101) C12N 2501/135 (20130101) C12N 2501/165 (20130101) C12N 2533/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286468 | Joung et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); Benjamin Kleinstiver (Medford, Massachusetts) |
| ABSTRACT | Engineered CRISPR-Cas9 nucleases with altered and improved PAM specificities and their use in genomic engineering, epigenomic engineering, and genome targeting. |
| FILED | Wednesday, August 22, 2018 |
| APPL NO | 16/109657 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 2319/71 (20130101) C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 9/0071 (20130101) C12N 9/78 (20130101) C12N 9/80 (20130101) C12N 9/1007 (20130101) C12N 9/1029 (20130101) C12N 15/11 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286469 | Raines et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Ronald T. Raines (Madison, Wisconsin); Trish Hoang (Madison, Wisconsin) |
| ABSTRACT | The present disclosure provides compositions, methods and kits for the treatment of cancer. Particularly, the present disclosure provides synergistic compositions comprising at least one cytotoxic ribonuclease and at least one MAPK-pathway inhibitor. |
| FILED | Thursday, November 08, 2018 |
| APPL NO | 16/184629 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class Enzymes C12Y 301/27005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286470 | Chavez et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Alejandro Chavez (New York, New York); Frank J. Poelwijk (Dallas, Texas); George M. Church (Brookline, Massachusetts) |
| ABSTRACT | Methods of making mutant Cas9 proteins are described. |
| FILED | Monday, April 20, 2020 |
| APPL NO | 16/852592 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) Enzymes C12Y 301/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 2333/922 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286473 | Dong et al. |
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| FUNDED BY |
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| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts); Paul Stenmark (Stockholm, Sweden) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Min Dong (Weatogue, Connecticut); Sicai Zhang (Boston, Massachusetts); Paul Stenmark (Stockholm, Sweden) |
| ABSTRACT | Provided herein are Clostridial Botulinum neurotoxin (BoNT) polypeptides of a novel serotype (BoNT/X) and methods of making and using the BoNT polypeptides, e.g., in therapeutic applications. |
| FILED | Friday, July 07, 2017 |
| APPL NO | 16/315698 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/00 (20130101) Peptides C07K 14/33 (20130101) C07K 2319/01 (20130101) C07K 2319/21 (20130101) C07K 2319/22 (20130101) C07K 2319/23 (20130101) C07K 2319/24 (20130101) C07K 2319/035 (20130101) C07K 2319/41 (20130101) C07K 2319/42 (20130101) C07K 2319/43 (20130101) C07K 2319/50 (20130101) C07K 2319/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) Original (OR) Class Enzymes C12Y 304/24069 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286478 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Feng Zhang (Cambridge, Massachusetts); Bernd Zetsche (Gloucester, Massachusetts); Winston Yan (Brookline, Massachusetts); Neville Espi Sanjana (New York, New York); Sara Jones (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA-targeting systems comprising a novel DNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA. |
| FILED | Wednesday, April 19, 2017 |
| APPL NO | 16/095253 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/63 (20130101) C12N 15/102 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) Enzymes C12Y 305/04005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286502 | Garg et al. |
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| FUNDED BY |
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| APPLICANT(S) | Texas Tech University System (Lubbock, Texas) |
| ASSIGNEE(S) | Texas Tech University System (Lubbock, Texas) |
| INVENTOR(S) | Himanshu Garg (El Paso, Texas); Anjali Joshi (El Paso, Texas) |
| ABSTRACT | The present invention includes compositions, methods, vectors, vaccines, cell lines and other constructs for making and used Zika virus Reporter Virus Particles (RVPs) and/or Virus Like Particles (VLPs) that are safe for handling and manufacturing and are able to generate an effective immune response against Zika virus and can be readily scaled up for cost-effective production. |
| FILED | Wednesday, June 20, 2018 |
| APPL NO | 16/620581 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2740/15043 (20130101) C12N 2770/24122 (20130101) C12N 2770/24123 (20130101) C12N 2770/24134 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286514 | Leng et al. |
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| FUNDED BY |
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| APPLICANT(S) | Fenfei Leng (Palmetto Bay, Florida); Zifang Deng (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Fenfei Leng (Palmetto Bay, Florida); Zifang Deng (Miami, Florida) |
| ABSTRACT | The present invention provides assays and methods for studying DNA topology and topoisomerases. The assays and methods utilize a circular plasmid DNA comprising one or more hairpin structures and the ability of T5 exonuclease (T5E) to digest the circular plasmid DNA in a specific configuration. The assays and methods can be used as a high throughput screening for inhibitors of, for example, DNA gyrases and DNA topoisomerases I for anticancer drug and antibiotics discovery. |
| FILED | Friday, October 16, 2020 |
| APPL NO | 17/072502 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/44 (20130101) C12Q 1/533 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 2021/6439 (20130101) G01N 2500/04 (20130101) G01N 2500/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286515 | Chee et al. |
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| FUNDED BY |
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| APPLICANT(S) | Prognosys Biosciences, Inc. (San Diego, California) |
| ASSIGNEE(S) | Prognosys Biosciences, Inc. (San Diego, California) |
| INVENTOR(S) | Mark S. Chee (San Diego, California); David A. Routenberg (San Diego, California) |
| ABSTRACT | The present disclosure provides methods and assay systems for use in spatially encoded biological assays, including assays to determine a spatial pattern of abundance, expression, and/or activity of one or more biological targets across multiple sites in a sample. In particular, the biological targets comprise proteins, and the methods and assay systems do not depend on imaging techniques for the spatial information of the targets. The present disclosure provides methods and assay systems capable of high levels of multiplexing where reagents are provided to a biological sample in order to address tag the sites to which reagents are delivered; instrumentation capable of controlled delivery of reagents; and a decoding scheme providing a readout that is digital in nature. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 17/358280 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) Original (OR) Class C12Q 1/6809 (20130101) C12Q 2565/513 (20130101) C12Q 2565/629 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286517 | Kishi et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Jocelyn Yoshiko Kishi (Boston, Massachusetts); Thomas E. Schaus (Arlington, Massachusetts); Peng Yin (Brookline, Massachusetts); Feng Xuan (Boston, Massachusetts); Nikhil Gopalkrishnan (Jamaica Plain, Massachusetts); Sungwook Woo (Chestnut Hill, Massachusetts) |
| ABSTRACT | The present disclosure provides, in some aspects, nucleic acid-based molecular tools that enable the recording of molecular structure and soluble signals as well as the programmed assembly of molecular structures. |
| FILED | Thursday, February 16, 2017 |
| APPL NO | 15/999245 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/64 (20130101) C12N 15/113 (20130101) C12N 2310/122 (20130101) C12N 2310/127 (20130101) C12N 2330/50 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6809 (20130101) C12Q 1/6811 (20130101) Original (OR) Class C12Q 1/6825 (20130101) C12Q 1/6825 (20130101) C12Q 1/6853 (20130101) C12Q 1/6853 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2525/186 (20130101) C12Q 2525/186 (20130101) C12Q 2525/204 (20130101) C12Q 2525/204 (20130101) C12Q 2525/301 (20130101) C12Q 2525/301 (20130101) C12Q 2525/301 (20130101) C12Q 2531/101 (20130101) C12Q 2531/101 (20130101) C12Q 2531/119 (20130101) C12Q 2531/119 (20130101) C12Q 2531/119 (20130101) C12Q 2533/101 (20130101) C12Q 2533/101 (20130101) C12Q 2537/16 (20130101) C12Q 2537/16 (20130101) C12Q 2537/149 (20130101) C12Q 2537/149 (20130101) C12Q 2537/157 (20130101) C12Q 2537/157 (20130101) C12Q 2537/163 (20130101) C12Q 2537/163 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1376 (20130101) C12Q 2537/1376 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286518 | Beckman et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Kenneth Beckman (Saint Paul, Minnesota); Daryl Gohl (Minneapolis, Minnesota) |
| ABSTRACT | Analytical standards can allow one to detect and/or measure sampling, processing, and/or amplification errors in a sample that includes a plurality of polynucleotide molecules. The analytical standards can provide an internal control to detect errors in the representation of the original sample reflected in data obtained after manipulating and/or processing of sample molecules. |
| FILED | Friday, May 05, 2017 |
| APPL NO | 16/099229 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6848 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 2545/101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286523 | Xie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Xiaoliang Sunney Xie (Lexington, Massachusetts); Katsuyuki Shiroguchi (Arlington, Massachusetts); Peter A. Sims (Cambridge, Massachusetts); Tony Z. Jia (Cambridge, Massachusetts) |
| ABSTRACT | Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided. |
| FILED | Tuesday, January 28, 2020 |
| APPL NO | 16/774104 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6853 (20130101) C12Q 1/6853 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2525/131 (20130101) C12Q 2525/301 (20130101) C12Q 2537/16 (20130101) C12Q 2563/179 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286529 | Storch |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Gregory Storch (Saint Louis, Missouri) |
| ABSTRACT | Disclosed are methods of diagnosis of a pathogen-associated disease. These methods comprise: providing a biological sample from a human subject; determining presence, absence and/or quantity of a bacterial pathogen, a viral pathogen, or a combination thereof, by a pathogen culture, a serum antibody detection test, a pathogen antigen detection test, a pathogen DNA and/or RNA detection test, or a combination thereof; determining in the sample, expression levels of at least one endogenous gene in which aberrant expression levels are associated with infection with a pathogen, by a microarray hybridization assay, RNA-seq assay, polymerase chain reaction assay, a LAMP assay, a ligase chain reaction assay, a Southern, Northern, or Western blot assay, an ELISA or a combination thereof. The subject can be diagnosed with the disease if the subject comprises the pathogen and an aberrant level of expression of an endogenous gene. |
| FILED | Friday, February 21, 2020 |
| APPL NO | 16/797733 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 45/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) C12Q 1/70 (20130101) C12Q 1/689 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56911 (20130101) G01N 33/56983 (20130101) G01N 2469/10 (20130101) G01N 2469/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286531 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Yuxuan Wang (Baltimore, Maryland); Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Luis Diaz (Ellicot City, Maryland); Nickolas Papadopoulos (Towson, Maryland); Karin Sundfeldt (Gothenburg, Sweden); Bjorg Kristjansdottir (Gothenburg, Sweden) |
| ABSTRACT | A diagnostic test for ovarian cysts is based on the detection of mutations characteristic of the most common neoplasms giving rise to these lesions. With this test, tumor-specific mutations were detected in the cyst fluids of 19 of 24 (79%) borderline tumors and 28 of 31 (90%) malignant ovarian cancers. In contrast, we detected no mutations in the cyst fluids from 10 non-neoplastic cysts and 12 benign tumors. When categorized by the need for exploratory surgery (i.e., presence of a borderline tumor or malignant cancer), the sensitivity of this test was 85% and the specificity was 100%. These tests could inform the diagnosis of ovarian cysts and improve the clinical management of the large number of women with these lesions. |
| FILED | Thursday, August 11, 2016 |
| APPL NO | 15/749887 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287414 | Ouyang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Zheng Ouyang (West Lafayette, Indiana); He Wang (West Lafayette, Indiana); Nicholas E. Manicke (West Lafayette, Indiana); Robert Graham Cooks (West Lafayette, Indiana); Qian Yang (West Lafayette, Indiana); Jiangjiang Liu (West Lafayette, Indiana) |
| ABSTRACT | The invention generally relates to a sample dispenser including an internal standard and methods of use thereof. |
| FILED | Thursday, July 23, 2020 |
| APPL NO | 16/936683 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/10 (20130101) G01N 1/28 (20130101) G01N 1/286 (20130101) G01N 33/491 (20130101) G01N 33/492 (20130101) Original (OR) Class G01N 33/48714 (20130101) G01N 33/48785 (20130101) G01N 2001/2893 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0009 (20130101) H01J 49/16 (20130101) H01J 49/0027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287444 | Lal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Ratneshwar Lal (La Jolla, California); Qingqing Yang (San Diego, California); Qian Ma (San Diego, California); Zhaowei Liu (San Diego, California) |
| ABSTRACT | Disclosed is an atomic force microscopy system includes a laser source configured to generate an optical probe beam containing light of different spectral light components at different optical wavelengths, a dispersive optical device positioned to receive the optical probe beam and configured to disperse the optical probe beam into different dispersed light beams that are at different optical wavelengths and are spatially separated from one another, a cantilever array including a plurality of cantilevers structured to detect a sample and configured to deflect the different dispersed light beams by moving in position based on an interaction with the sample to produce multiple deflected output beams at different output optical wavelengths from the cantilevers, and a plurality of photodetectors to receive the multiple deflected output beams of different wavelengths from the cantilevers, respectively. |
| FILED | Tuesday, October 08, 2019 |
| APPL NO | 17/283929 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 20/02 (20130101) Original (OR) Class G01Q 60/40 (20130101) G01Q 60/42 (20130101) G01Q 70/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287540 | Olcott et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RefleXion Medical, Inc. (Hayward, California) |
| ASSIGNEE(S) | RefleXion Medical, Inc. (Hayward, California) |
| INVENTOR(S) | Peter Demetri Olcott (Los Gatos, California); Matthew Francis Bieniosek (Danville, California); Brent Harper (New Glarus, Wisconsin) |
| ABSTRACT | Disclosed herein are methods and devices for the acquisition of positron emission (or PET) data in the presence of ionizing radiation that causes afterglow of PET detectors. In one variation, the method comprises adjusting a coincidence trigger threshold of the PET detectors during a therapy session. In one variation, the method comprises adjusting a gain factor used in positron emission data acquisition (e.g., a gain factor used to multiply and/or shift the output(s) of a PET detector(s)) during a therapy session. In some variations, a method for acquiring positron emission data during a radiation therapy session comprises suspending communication between the PET detectors and a signal processor of a controller for a predetermined period of time after a radiation pulse has been emitted by the linac. |
| FILED | Friday, May 29, 2020 |
| APPL NO | 16/887896 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/172 (20130101) G01T 1/208 (20130101) G01T 1/2023 (20130101) G01T 1/2985 (20130101) Original (OR) Class G01T 7/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287633 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Jonathan T. C. Liu (Seattle, Washington); Lindsey A. Barner (Seattle, Washington); Adam K. Glaser (Seattle, Washington) |
| ABSTRACT | Apparatuses, systems, and methods for solid immersion meniscus lenses (SIMlenses). An optical system may include a sample holder with a first side which supports a sample, and a second side opposite the first side. The second side of the sample holder may be in contact with an immersion fluid. Light passing between the sample and an objective lens may pass through the sample holder, immersion fluid, and a SIMlens positioned between the immersion fluid and objective. The SIMlens may have a first curved surface and a second curved surface, each of which may be shaped to match a wavefront of the light as it passes through the SIMlens. The immersion fluid, SIMlens, and environment containing the objective may all have different refractive indices. |
| FILED | Wednesday, June 23, 2021 |
| APPL NO | 17/356135 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/26 (20130101) G02B 21/0032 (20130101) G02B 21/33 (20130101) Original (OR) Class G02B 21/248 (20130101) G02B 21/367 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11288846 | Treilhard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | KONINKLIJKE PHILIPS N.V. (Eindhoven, Netherlands); Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | KONINKLIJKE PHILIPS N.V. (Eindhoven, Netherlands); YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | John Treilhard (New Haven, Connecticut); Ming De Lin (New Haven, Connecticut); Jean-François Geschwind (Eindhoven, Netherlands); James Duncan (New Haven, Connecticut); Susanne Smolka (New Haven, Connecticut) |
| ABSTRACT | In an image guidance method, a stream of cone-beam computed tomography (CBCT) images of an anatomical organ is acquired using a CBCT imaging device (34). For each CBCT image (44), the surface of the organ in the CBCT image is segmented to generate a segmented surface (70) of the anatomical organ in the CBCT image. Occluded shape reconstruction (66) using a statistical shape prior (68) may be used to reconstruct a missing or occluded surface portion. A pre-operative medical image (12) of the anatomical organ and the CBCT image are spatially registered by warping one of the images to the other of the images using point set registration of a segmented surface (30) of the organ in the preoperative medical image and the segmented surface of the organ in the CBCT image. A fused image (82) is displayed that combines the warped image and the other image. |
| FILED | Thursday, September 28, 2017 |
| APPL NO | 16/333612 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/12 (20170101) G06T 7/0014 (20130101) G06T 7/0016 (20130101) G06T 7/143 (20170101) G06T 7/344 (20170101) G06T 11/003 (20130101) Original (OR) Class G06T 2200/24 (20130101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/10121 (20130101) G06T 2207/20076 (20130101) G06T 2207/20221 (20130101) G06T 2207/30056 (20130101) G06T 2207/30096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11289301 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tiezhi Zhang (St. Louis, Missouri); Praneeth Kandlakunta (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Tiezhi Zhang (St. Louis, Missouri); Praneeth Kandlakunta (St. Louis, Missouri) |
| ABSTRACT | A multi-pixel x-ray source is provided. The x-ray source includes a plurality of transmission target assemblies. The transmission target assembly includes a tungsten target and a diamond substrate. The substrate includes a first transmission surface and a second transmission surface opposite first transmission surface. The substrate further includes a first side surface and a second side surface disposed between the first and second transmission surfaces. The target covers the first transmission surface of the substrate. The transmission target assembly further includes a base. The base surrounds the first and second side surfaces of substrate, exposing a collimator surface of the second transmission surface and the target. The transmission target assembly is configured to transmit x-ray generated by the target through the target and the substrate. |
| FILED | Friday, November 06, 2020 |
| APPL NO | 17/091744 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Electric Digital Data Processing G06F 30/20 (20200101) Electric Discharge Tubes or Discharge Lamps H01J 35/12 (20130101) H01J 35/116 (20190501) Original (OR) Class H01J 2235/081 (20130101) H01J 2235/083 (20130101) X-ray Technique H05G 1/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11289879 | Yun |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Seok Hyun Yun (Belmont, Massachusetts) |
| ABSTRACT | Disclosed are photonic particles and methods of using particles in biological samples. The particles are configured to emit laser light when energetically stimulated by, e.g., a pump source. The particles may include a gain medium with inorganic materials, an optical cavity with high refractive index, and a coating with organic materials. The particles may be smaller than 3 microns along their longest axes. The particles may attach to each other to form, e.g., doublets and triplets. The particles may be injection-locked by coupling an injection beam into a particle while pumping so that an injection seed is amplified to develop into laser oscillation. A microscopy system may include a pump source, beam scanner, spectrometer with resolution of less than 1 nanometer and acquisition rate of more than 1 kilohertz, and spectral analyzer configured to distinguish spectral peaks of laser output from broadband background. |
| FILED | Monday, June 08, 2020 |
| APPL NO | 16/895914 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 2003/2826 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/648 (20130101) G01N 2015/1006 (20130101) G01N 2021/6439 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/091 (20130101) H01S 3/169 (20130101) H01S 3/213 (20130101) H01S 3/0604 (20130101) H01S 5/36 (20130101) H01S 5/40 (20130101) H01S 5/041 (20130101) H01S 5/1025 (20130101) H01S 5/1067 (20130101) Original (OR) Class H01S 5/1075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11284851 | Madabhushi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Thomas Atta-Fosu (Cleveland Heights, Ohio); Soumya Ghose (Niskayuna, New York) |
| ABSTRACT | Embodiments access a set of radiological images acquired from a population of subjects, where a member of the set of radiological images includes a left atrium (LA) region; construct a statistical shape differential atlas from the images; generate a template LA model from the statistical shape differential atlas, where the template LA model includes a site of interest (SOI); acquire a pre-ablation radiological image of a region of tissue in a patient demonstrating atrial fibrillation (AF) pathology; generate a patient LA model from the pre-ablation image; compute a deformation field that registers the SOI to the patient LA model using deformable registration; compute a patient feature vector based on the deformation field; generate an AF probability score for the patient based on the feature vector; generate a classification of the patient based, at least in part, on the AF probability score; and display the classification or the AF probability score. |
| FILED | Friday, March 22, 2019 |
| APPL NO | 16/361421 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/361 (20210101) A61B 6/032 (20130101) A61B 6/54 (20130101) A61B 6/463 (20130101) A61B 6/469 (20130101) A61B 6/503 (20130101) Original (OR) Class A61B 6/5217 (20130101) A61B 2018/00351 (20130101) A61B 2018/00577 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 2207/30048 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 30/40 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285046 | Harrand et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CFD Research Corporation (Huntsville, Alabama) |
| ASSIGNEE(S) | CFD Research Corporation (Huntsville, Alabama) |
| INVENTOR(S) | Vincent Johannes Harrand (Huntsville, Alabama); David Keith Sedberry, Jr. (Huntsville, Alabama); Phillip Edward Whitley (Miami, Florida); Xiangguang Gary Tan (Alexandria, Virginia); Andrzej Przekwas (Huntsville, Alabama) |
| ABSTRACT | A passive non-linear earplug can include: a tapered body having a channel extending from a wider distal end to a narrower proximal end, the tapered body having shape memory and size adapted for being received into an ear canal of a human subject; and a disk attached to the wider distal end of the tapered body, the disk having one or more holes aligned with the channel. A structural tube can be located in the channel. A handle can be attached to the tapered body and/or disk. An annular member can be coupled to the disk opposite of the tapered body, the annular member having an aperture that at least partially aligns with the channel. A tube member can be coupled to the disk opposite of the tapered body. The earplug can attenuate loud sounds while allowing normal sounds to be heard, which provides for the non-linearity. |
| FILED | Wednesday, September 20, 2017 |
| APPL NO | 15/710646 |
| ART UNIT | 3786 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 11/08 (20130101) Original (OR) Class A61F 2011/085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285204 | Dutta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Army (Fort Detrick, Maryland) |
| ASSIGNEE(S) | THE GOVERNMENT OF THE UNITED STATES, AS REPRESEN (Fort Detrick, Maryland) |
| INVENTOR(S) | Sheetij Dutta (Silver Spring, Maryland); Adrian Batchelor (Baltimore, Maryland); Farhat Khan (Columbia, Maryland); Mark Langowski (Vienna, Virginia) |
| ABSTRACT | The disclosure generally provides recombinant proteins comprising Tobamovirus capsid proteins and an immunogenic epitope of an antigen of interest. The recombinant protein can be used to assemble an array comprising a plurality of associated recombinant proteins that can enhance the immunogenicity of the epitope and induce and/or enhance an immune response to the antigen. The disclosure also provides compositions, such as vaccines, that include the recombinant protein as well as methods for inducing and/or enhancing an immune response in a mammal. |
| FILED | Friday, September 21, 2018 |
| APPL NO | 16/649567 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 39/015 (20130101) A61K 2039/64 (20130101) A61K 2039/5258 (20130101) A61K 2039/6075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285319 | Hubbard et al. |
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| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Ryan J. Hubbard (Woodland Hills, California); Praveen K. Pilly (West Hills, California) |
| ABSTRACT | A neuro-stimulation system comprising a user interface arranged for providing a user with a series of sensory stimuli, and for selecting, in response to a user input a group of selected sensory stimuli out of said series of sensory stimuli; a non-invasive brain stimulator arranged for stimulating the brain of the user with a different, unique, associated brain stimulus each time the user interface selects one stimulus of said group of selected sensory stimuli; and a controller arranged for detecting slow-wave sleep of the user and for causing the stimulator to stimulate the brain of the user with the brain stimuli associated with said group of selected sensory stimuli during the slow-wave sleep of the user. |
| FILED | Thursday, April 04, 2019 |
| APPL NO | 16/375593 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/024 (20130101) A61B 5/0205 (20130101) A61B 5/369 (20210101) A61B 5/0816 (20130101) A61B 5/4812 (20130101) A61B 5/6803 (20130101) A61B 5/7475 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0456 (20130101) A61N 1/36025 (20130101) Original (OR) Class A61N 1/36031 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285320 | Choe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Jaehoon Choe (Agoura Hills, California); Praveen K. Pilly (West Hills, California) |
| ABSTRACT | A neuro-stimulation system having: a controller; a user interface arranged for, under control of the controller, providing a user with a series of information elements to be learned by the user; a non-invasive brain stimulator arranged for, under the control of the controller, tagging each information element of said series of information elements by stimulating a brain of the user with a different, unique, associated brain stimulus when the user is provided said information element by said user interface; and a non-invasive brain sensor arranged for sending to the controller data indicating a slow-wave sleep period of the user; wherein the controller is further arranged for cueing each information element of said series of information elements by causing the stimulator to stimulate the brain of the user with the brain stimuli associated with said series of information elements during said slow-wave sleep period of the user. |
| FILED | Thursday, April 04, 2019 |
| APPL NO | 16/375598 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/291 (20210101) A61B 5/4809 (20130101) A61B 5/6814 (20130101) A61B 5/7475 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0456 (20130101) A61N 1/3603 (20170801) Original (OR) Class Electric Digital Data Processing G06F 9/542 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 19/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285456 | Siu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Numat Technologies Inc. (Skokie, Illinois) |
| ASSIGNEE(S) | NuMat Technologies, Inc. (Skokie, Illinois) |
| INVENTOR(S) | Paul Wai-Man Siu (Chicago, Illinois) |
| ABSTRACT | This invention relates to a Cu-BTC MOF which is water stable. The Cu-BTC MOF has open coordination sites and has been post synthesis modified by partially occupying the open sites with a ligand such as acetonitrile (CH3CN). The resultant MOF retains at least 40% of its as synthesized surface area after exposure to liquid water at 60° C. for 6 hours. This is an unexpected result versus the MOF which has not been post treated with ligands such as acetonitrile. This MOF can be used to abate contaminants such as ammonia in gas streams and especially air streams. |
| FILED | Friday, August 14, 2020 |
| APPL NO | 16/993886 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/58 (20130101) B01D 53/82 (20130101) B01D 53/8634 (20130101) B01D 2253/204 (20130101) B01D 2255/705 (20130101) B01D 2255/9207 (20130101) B01D 2257/406 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/226 (20130101) Original (OR) Class B01J 20/3085 (20130101) B01J 20/28016 (20130101) B01J 20/28019 (20130101) B01J 20/28038 (20130101) B01J 20/28045 (20130101) B01J 20/28066 (20130101) B01J 20/28073 (20130101) B01J 31/1691 (20130101) B01J 35/04 (20130101) B01J 35/08 (20130101) B01J 35/026 (20130101) B01J 35/1028 (20130101) B01J 37/04 (20130101) B01J 37/10 (20130101) B01J 2231/005 (20130101) B01J 2531/16 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285572 | Tindal |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Mitchell Tindal (Hartland, Wisconsin) |
| ABSTRACT | A tripod jack cylinder removal tool including a lifting eyebolt attached through an up flange and further through and up flange aperture to a lock nut. The flange is secured to a pipe at a pipe top end, the pipe further having a bottom end wherein a down flange having a down flange aperture is attached to the pipe and a bolt having threads protrudes through a down flange aperture. |
| FILED | Sunday, May 23, 2021 |
| APPL NO | 17/327738 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 19/04 (20130101) Original (OR) Class Hoisting, Lifting, Hauling or Pushing, Not Otherwise Provided For, e.g Devices Which Apply a Lifting or Pushing Force Directly to the Surface of a Load B66F 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285616 | Penning et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Teradyne, Inc. (North Reading, Massachusetts) |
| ASSIGNEE(S) | Teradyne, Inc. (North Reading, Massachusetts) |
| INVENTOR(S) | Ryan S. Penning (Madison, Wisconsin); Ralph F. Polimeni, Jr. (Reno, Nevada); Brett L. Limone (Danvers, Massachusetts); James D. English (Alva, Florida) |
| ABSTRACT | The specification and drawings present a robotic coating application system and a method for coating at least one part with a robotic coating application system. The robotic coating application system may comprise an enclosure configured to receive at least one part. The robotic coating application system may further comprise at least one robot configured to operate at least partially within the enclosure. The robotic coating application system may also comprise a graphical user interface to display a model of the at least one part and allow a user to select a portion or subportion of the model for application of a coating. The coating may be automatically applied to the at least one part based upon, at least in part, the user-selected portion or subportion. |
| FILED | Tuesday, September 11, 2018 |
| APPL NO | 16/127960 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 13/0431 (20130101) Apparatus for Applying Fluent Materials to Surfaces, in General B05C 5/0212 (20130101) B05C 5/0216 (20130101) B05C 9/10 (20130101) B05C 13/02 (20130101) B05C 15/00 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0081 (20130101) B25J 9/163 (20130101) B25J 11/0075 (20130101) Original (OR) Class B25J 13/06 (20130101) B25J 13/081 (20130101) B25J 15/0066 (20130101) B25J 19/022 (20130101) B25J 19/023 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286269 | Kerr et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Indian Head, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Andrew T. Kerr (Alexandria, Virginia); Colt T. Hendley, IV (Lanham, Maryland); Owen T. O'Sullivan (Alexandria, Virginia) |
| ABSTRACT | Methods for synthesizing in situ two energetic compounds. A first energetic compound being characterized by a first local structure that features metal centers bound by 1-tetrazole, 4-cyanobenzene and azide molecules, while a second energetic compound is characterized by a second local structure that features metal centers bound by 1-methyltetrazole and azide molecules. Both energetic compounds may further be characterized as crystalline coordination polymers (CPs). |
| FILED | Thursday, August 27, 2020 |
| APPL NO | 16/873954 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286391 | Champagne, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts); U.S. Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts); U.S. ARMY RESEARCH LABORATORY (Adelphi, Maryland) |
| INVENTOR(S) | Victor Kenneth Champagne, Jr. (Dudley, Massachusetts); Jessica Deborah Schiffman (Amherst, Massachusetts); John Klier (Leverett, Massachusetts); Guozhen Yang (Amherst, Massachusetts); Mengfei Huang (Amherst, Massachusetts) |
| ABSTRACT | In an embodiment, a composition comprises a plurality of reactive particles; wherein at least a first portion of the reactive particles comprises a first reactive monomer located in a first matrix polymer; wherein the first reactive monomer comprises a self-reactive monomer or wherein the first reactive monomer can polymerize with a second reactive monomer located in a second matrix polymer of a second portion of the reactive particles to form a coating polymer. In another embodiment, a method of making the plurality of reactive particles, comprises polymerizing a first matrix monomer in the presence of the first reactive monomer; or polymerizing the first matrix monomer to form a plurality of particles and swelling the plurality of particles with the first reactive monomer. In another embodiment, a method comprises cold spraying the plurality of reactive particles. |
| FILED | Monday, April 09, 2018 |
| APPL NO | 16/497880 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/12 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 4/06 (20130101) Original (OR) Class C09D 5/03 (20130101) C09D 7/70 (20180101) C09D 133/12 (20130101) C09D 163/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286492 | Thess et al. |
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| FUNDED BY |
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| APPLICANT(S) | CureVac AG (Tübingen, Germany) |
| ASSIGNEE(S) | CureVac AG (Tübingen, Germany) |
| INVENTOR(S) | Andreas Thess (Kusterdingen, Germany); Thomas Schlake (Gundelfingen, Germany); Stefanie Grund (Stuttgart, Germany) |
| ABSTRACT | The invention relates to an artificial nucleic acid molecule comprising an open reading frame and a 3′-UTR comprising at least one poly(A) sequence or a polyadenylation signal. The invention further relates to a vector comprising the artificial nucleic acid molecule comprising an open reading frame and a 3′-UTR comprising at least one poly(A) sequence or a polyadenylation signal, to a cell comprising the artificial nucleic acid molecule or the vector, to a pharmaceutical composition comprising the artificial nucleic acid molecule or the vector and to a kit comprising the artificial nucleic acid molecule, the vector and/or the pharmaceutical composition. The invention also relates to a method for increasing protein production from an artificial nucleic acid molecule and to the use of a 3′-UTR for a method for increasing protein production from an artificial nucleic acid molecule. Moreover, the invention concerns the use of the artificial nucleic acid molecule, the vector, the kit or the pharmaceutical composition as a medicament, as a vaccine or in gene therapy. |
| FILED | Friday, August 20, 2021 |
| APPL NO | 17/408332 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/145 (20130101) A61K 39/205 (20130101) A61K 48/00 (20130101) A61K 2039/53 (20130101) A61K 2039/54 (20130101) A61K 2039/575 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/67 (20130101) Original (OR) Class C12N 15/68 (20130101) C12N 15/85 (20130101) C12N 2760/16134 (20130101) C12N 2760/16171 (20130101) C12N 2760/20134 (20130101) C12N 2760/20171 (20130101) C12N 2830/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286517 | Kishi et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Jocelyn Yoshiko Kishi (Boston, Massachusetts); Thomas E. Schaus (Arlington, Massachusetts); Peng Yin (Brookline, Massachusetts); Feng Xuan (Boston, Massachusetts); Nikhil Gopalkrishnan (Jamaica Plain, Massachusetts); Sungwook Woo (Chestnut Hill, Massachusetts) |
| ABSTRACT | The present disclosure provides, in some aspects, nucleic acid-based molecular tools that enable the recording of molecular structure and soluble signals as well as the programmed assembly of molecular structures. |
| FILED | Thursday, February 16, 2017 |
| APPL NO | 15/999245 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/64 (20130101) C12N 15/113 (20130101) C12N 2310/122 (20130101) C12N 2310/127 (20130101) C12N 2330/50 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6809 (20130101) C12Q 1/6811 (20130101) Original (OR) Class C12Q 1/6825 (20130101) C12Q 1/6825 (20130101) C12Q 1/6853 (20130101) C12Q 1/6853 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2525/186 (20130101) C12Q 2525/186 (20130101) C12Q 2525/204 (20130101) C12Q 2525/204 (20130101) C12Q 2525/301 (20130101) C12Q 2525/301 (20130101) C12Q 2525/301 (20130101) C12Q 2531/101 (20130101) C12Q 2531/101 (20130101) C12Q 2531/119 (20130101) C12Q 2531/119 (20130101) C12Q 2531/119 (20130101) C12Q 2533/101 (20130101) C12Q 2533/101 (20130101) C12Q 2537/16 (20130101) C12Q 2537/16 (20130101) C12Q 2537/149 (20130101) C12Q 2537/149 (20130101) C12Q 2537/157 (20130101) C12Q 2537/157 (20130101) C12Q 2537/163 (20130101) C12Q 2537/163 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1376 (20130101) C12Q 2537/1376 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286525 | Tsalik et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Ephraim L. Tsalik (Cary, North Carolina); Geoffrey S. Ginsburg (Durham, North Carolina); Christopher W. Woods (Durham, North Carolina); Ricardo Henao Giraldo (Durham, North Carolina); Rachel A. Myers (Raleigh, North Carolina) |
| ABSTRACT | The present disclosure provides methods for determining whether a subject has sepsis, or is at risk of developing sepsis, and methods of treating the subject based on the determination. Also provided are methods for determining an increased risk of mortality in a subject with sepsis or suspected of having sepsis, and methods of treating the subject based on the determination. Systems useful for the same are also provided. |
| FILED | Tuesday, January 16, 2018 |
| APPL NO | 16/478202 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286711 | Judson et al. |
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| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by The Secretary of The Army (Alexandria, Virginia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
| INVENTOR(S) | John S Judson (Vicksburg, Mississippi); David V Senior (Vicksburg, Mississippi); Craig R Ackerman (Gainesville, Virginia); Daniel Duke (Washington, District of Columbia) |
| ABSTRACT | Blast, ballistic, and entry resistant compression frame systems include a plurality of bolts, an exterior frame assembly having a peripheral flange and a plurality of sleeves that receive the bolts, an interior frame assembly having a peripheral flange and a plurality of apertures that receive the bolts therethrough, an exterior gasket between the peripheral flange of the exterior frame assembly and an exterior surface of the wall of the building, and an interior gasket between the peripheral flange of the interior frame assembly and an interior surface of the wall of the building. The exterior frame assembly peripheral flange and the interior frame assembly peripheral flange apply a compression force to the wall when the bolts are torque tightened into the threaded sleeves. Methods of installation in a wall of a building are also provided. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/589063 |
| ART UNIT | 3635 — Static Structures, Supports and Furniture |
| CURRENT CPC | Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 5/106 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286789 | Ghigliotty et al. |
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| FUNDED BY |
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| APPLICANT(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Jaime G Ghigliotty (Cabo Rojo, Puerto Rico); David J Candelori (Glastonbury, Connecticut); San Quach (Southington, Connecticut) |
| ABSTRACT | An airfoil for a gas turbine engine is disclosed. In various embodiments, the airfoil includes a cooling passage; an outer wall separating a core flow path from the cooling passage; a diffuser in fluid communication with the cooling passage and opening into the core flow path, the diffuser being characterized by a linear ridge on a downstream end of the diffuser; and a thermal barrier coating covering the outer wall and the linear ridge. |
| FILED | Thursday, July 02, 2020 |
| APPL NO | 16/920014 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/186 (20130101) Original (OR) Class F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/90 (20130101) F05D 2240/12 (20130101) F05D 2240/14 (20130101) F05D 2240/35 (20130101) F05D 2250/12 (20130101) F05D 2260/202 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286790 | Quach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | San Quach (East Hartford, Connecticut); Christopher King (Bristol, Connecticut); Tracy A. Propheter-Hinckley (Manchester, Connecticut) |
| ABSTRACT | A gas turbine engine component includes a wall that has an inner surface and an outer surface. An inlet is defined by the inner surface. At least one non-rectangular slot is defined by the outer surface and includes at least one protrusion extending into the slot. A slot passage fluidly connects the inlet to the at least one non-rectangular slot. The slot passage comprises an inlet portion that extends through the wall from the inlet to an intermediate portion. An outlet portion extends through the wall from the intermediate portion to the at least one non-rectangular slot. |
| FILED | Wednesday, September 02, 2020 |
| APPL NO | 17/009936 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/186 (20130101) Original (OR) Class F01D 9/041 (20130101) F01D 11/08 (20130101) F01D 25/12 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/18 (20130101) Non-positive-displacement Pumps F04D 29/324 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/12 (20130101) F05D 2240/30 (20130101) F05D 2240/35 (20130101) F05D 2250/13 (20130101) F05D 2250/182 (20130101) F05D 2250/183 (20130101) F05D 2250/184 (20130101) F05D 2250/185 (20130101) F05D 2260/202 (20130101) F05D 2260/204 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 2900/03042 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286805 | Brostmeyer et al. |
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| FUNDED BY |
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| APPLICANT(S) | Florida Turbine Technologies, Inc. (Jupiter, Florida) |
| ASSIGNEE(S) | Florida Turbine Technologies, Inc. (Jupiter, Florida) |
| INVENTOR(S) | Joseph D. Brostmeyer (Jupiter, Florida); Robert A. Ress, Jr. (Carmel, Indiana); Tyler W. Sloss (Chapel Hill, North Carolina); Barry J. Brown (Jupiter, Florida) |
| ABSTRACT | A geared turbofan engine with at least one compression stage and at least one turbine stage on a high speed shaft, the high speed shaft coupled through a speed reduction gear box to a low speed shaft with a fan and a starter/generator. The low speed shaft is collinear with the high speed shaft but does not rotate within the high speed shaft. The speed reduction gear box is positioned between and mechanically couples the high speed shaft and the low speed shaft, which allows the fan and the integrated starter/generator on the low speed shaft to operate at a lower speed than the high speed shaft. |
| FILED | Monday, June 22, 2020 |
| APPL NO | 16/908566 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 15/10 (20130101) F01D 15/12 (20130101) Original (OR) Class F01D 25/16 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/06 (20130101) F02C 7/32 (20130101) F02C 7/36 (20130101) F02C 7/275 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286853 | Cerny et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Matthew Robert Cerny (West Chester, Ohio); Christopher James Kroger (Cincinnati, Ohio); Brandon Wayne Miller (Cincinnati, Ohio) |
| ABSTRACT | A thermal management system for a gas turbine engine and/or an aircraft is provided including a thermal transport bus having a heat exchange fluid flowing therethrough. The thermal management system also includes a plurality of heat source exchangers and at least one heat sink exchanger. The plurality of heat source exchangers and the at least one heat sink exchanger are in thermal communication with the heat exchange fluid in the thermal transport bus. The plurality of heat source exchangers are arranged along the thermal transport bus and configured to transfer heat from one or more accessory systems to the heat exchange fluid, and the at least one heat sink exchanger is located downstream of the plurality of heat source exchangers and configured to remove heat from the heat exchange fluid. |
| FILED | Monday, October 22, 2018 |
| APPL NO | 16/167408 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/06 (20130101) Original (OR) Class F02C 7/14 (20130101) F02C 7/16 (20130101) F02C 7/185 (20130101) F02C 7/224 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/213 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 1/00 (20130101) F25B 41/31 (20210101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/00 (20130101) F28D 2021/0021 (20130101) F28D 2021/0026 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 27/02 (20130101) F28F 2250/08 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286881 | Boyd et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana) |
| INVENTOR(S) | Douglas Boyd (Indianapolis, Indiana); Douglas D. Dierksmeier (Franklin, Indiana); Douglas J. Snyder (Carmel, Indiana); Graham Burkholder (Avon, Indiana); William B. Bryan (Indianapolis, Indiana) |
| ABSTRACT | A gas turbine engine system includes a gas turbine engine having a fan bypass duct, a heat exchanger system, and a flow transfer unit configured to selectively allow or preclude flow between the fan bypass duct and the heat exchanger system. A controller is coupled to and configured to vary the state of one or more of a fan exit nozzle, a heat exchanger exit nozzle, and a flow control valve controlling flow between the fan bypass duct and the heat exchanger system. |
| FILED | Wednesday, October 16, 2019 |
| APPL NO | 16/654706 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) F02C 6/08 (20130101) F02C 7/18 (20130101) F02C 7/185 (20130101) F02C 9/18 (20130101) Jet-propulsion Plants F02K 1/74 (20130101) Original (OR) Class F02K 3/06 (20130101) F02K 3/115 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/36 (20130101) F05D 2220/323 (20130101) F05D 2240/35 (20130101) F05D 2260/213 (20130101) F05D 2260/606 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287086 | Mitchell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wavefront Research, Inc. (Bethlehem, Pennsylvania) |
| ASSIGNEE(S) | Wavefront Research, Inc. (Northhampton, Pennsylvania) |
| INVENTOR(S) | Thomas A. Mitchell (Bethlehem, Pennsylvania); Jonas D. Corl (Bethlehem, Pennsylvania) |
| ABSTRACT | A system including an optical system having at least one refractive or reflective element, the optical system configured to substantially receive electromagnetic radiation emanating from a source, the optical system being located within a Dewar, a support structure, support structure being mechanically disposed between the optical system and a surface of the Dewar, the support structure having substantially low thermal conductance, a cold source; the cold source being located within the Dewar, a thermal link, the thermal link being mechanically disposed between the optical system and the cold source, the thermal link being substantially flexible and having substantially high thermal conductance. |
| FILED | Friday, April 20, 2018 |
| APPL NO | 15/958190 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 3/085 (20130101) Original (OR) Class F17C 2250/07 (20130101) F17C 2250/038 (20130101) F17C 2250/0478 (20130101) F17C 2250/0491 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287117 | Ross et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | First-Light USA, LLC (Seymour, Illinois) |
| ASSIGNEE(S) | First-Light USA, LLC (Seymour, Illinois) |
| INVENTOR(S) | Jeremy B. Ross (Monticello, Illinois); Blake S. Good (Urbana, Illinois); Jacob A. Flagle (New Palestine, Indiana) |
| ABSTRACT | A frame having a clip for securing the frame to an article of clothing or other object. The frame includes a mount for receiving a removable module and a rotatably attached clip. The clip includes an opening for accommodating sewing ribs between portions of a webbing and a gate (which may be a locking wire) moveable between an open position and a closed position at one end of the opening. In the open position, the locking wire removably engages one of a pair of elongated members defining the opening, e.g., by removably engaging that elongated member at a recess in an outside edge thereof, and does not obstruct the opening. When in the closed position, the locking wire removably engages the other of the elongated members, for example by removably engaging that other elongated member at a recess in its outside edge, and obstructs the longitudinal opening. |
| FILED | Monday, August 03, 2020 |
| APPL NO | 16/983252 |
| ART UNIT | 2875 — Optics |
| CURRENT CPC | Lighting Devices or Systems Thereof, Being Portable or Specially Adapted for Transportation F21L 4/027 (20130101) F21L 4/045 (20130101) Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 21/145 (20130101) F21V 21/0885 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to Uses or Applications of Lighting Devices or Systems F21W 2111/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287229 | Panchal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Viral Panchal (Parlin, New Jersey); Chong Peng (Mason, Ohio); Dale Conti (Andover, New Jersey); Ming-Wan Young (Basking Ridge, New Jersey); Tianyi Huang (Tenafly, New Jersey) |
| ABSTRACT | The present invention is directed to a process for making combustible foam celluloid munition parts having high aspect ratios, different densities or having an insert embedded into the foam celluloid munition part. The process for making such foam celluloid munition part requires pre-soaking dry particles of celluloid, placing the celluloid particles into a munition part mold, exposing the celluloid particles to high heat and pressure until the celluloid particles expand and fuse into the shape of the mold. Varying the density or the size of the celluloid particles used in the process produces munition parts having different densities. In addition, the placement of inserts into the particles prior to exposure to high heat and pressure produces munition parts having inserts that are useful for identification and tracking of such parts. |
| FILED | Wednesday, January 29, 2020 |
| APPL NO | 16/775307 |
| ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 44/1266 (20130101) B29C 44/3461 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2001/18 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/7772 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/122 (20130101) C08J 2203/06 (20130101) C08J 2301/08 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 5/188 (20130101) Original (OR) Class F42B 5/192 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287234 | Hardt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Lee R. Hardt (Ridgecrest, California); Donald L. Burnett (Spearfish, South Dakota); Josiah S. Garfield (Ridgecrest, California); Robert A. Koontz (Anchorage, Alaska); Eric K. Wooding (Ridgecrest, California); Que T. BuiDang (Ridgecrest, California) |
| ABSTRACT | The disclosed embodiments are directed to enhancing insensitive munitions performance. Some of the embodiments employ an outgassing pad having unique geometrical configurations, compositions, and positioning. Other embodiments rely on using thermally-releasable components to foster billet expulsion. Additional embodiments combine both aspects into entire cook-off mitigation systems for insensitive munitions improvements. |
| FILED | Thursday, May 07, 2020 |
| APPL NO | 16/868756 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 17/16 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/20 (20130101) F42B 12/207 (20130101) Original (OR) Class F42B 39/14 (20130101) F42B 39/20 (20130101) Ammunition Fuzes; Arming or Safety Means Therefor F42C 19/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287237 | Pirozzi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | John Pirozzi (Holmdel, New Jersey); Lloyd Khuc (Wharton, New Jersey); Daniel Altamura (Budd Lake, New Jersey); Lei Zheng (Morris Plains, New Jersey); William Leach (Columbia, New Jersey) |
| ABSTRACT | In a projectile launch environment, a fuzing safety device independently generates its own voltage upon setback which then is then used to arm the projectile. The arming is done independently of any on board battery rise time, and setback scenarios are detected free of false impacts such as dropping or jostling. The fuzing safety device includes a piezoelectric sensor for detecting motion in the projectile. |
| FILED | Thursday, September 03, 2020 |
| APPL NO | 17/010974 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition Fuzes; Arming or Safety Means Therefor F42C 15/24 (20130101) Original (OR) Class F42C 15/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287238 | Albrecht |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Nicholas H. Albrecht (Ridgecrest, California) |
| ABSTRACT | The embodiments are directed to methods of initiating insensitive explosive formulations. The disclosed methods include positioning a donor explosive pellet adjacent to an insensitive acceptor explosive pellet having a plurality of relative percent theoretical maximum density (TMD) zones. The insensitive acceptor explosive pellet is adjacent to an insensitive explosive fill. Upon donor explosive pellet initiation, the donor explosive pellet provides a shock stimulus to the insensitive acceptor explosive pellet, which initiates the insensitive acceptor explosive pellet, causing a detonation wave to be driven through the plurality of relative percent TMD zones and into the insensitive explosive fill. |
| FILED | Wednesday, December 02, 2020 |
| APPL NO | 17/109691 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition Fuzes; Arming or Safety Means Therefor F42C 19/0815 (20130101) Original (OR) Class F42C 19/0838 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287239 | Polk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Combat Capabilities Development Command, Chemical Biological Center (Apg, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Amee L Polk (Havre de Grace, Maryland); Joseph A Domanico (Bel Air, Maryland); Michael F Kauzlarich (Edgewood, Maryland); Nino L Bonavito (Perry Hall, Maryland); Warren L Gardner (Bel Air, Maryland) |
| ABSTRACT | A fast utility access device (FUAD) is provided that includes one or more casings, each of the one or more casings collectively defining a bore, and a core of a highly exothermic composition contained in the bore and surrounded by a thermally insulating inner liner, the highly exothermic composition ignitable to create a post-ignition temperature of between 500° C. and 4000° C. A method is also provided for breaching a target and includes contacting the inventive access device with a breaching target substrate, thermally coupling at least one reaction initiator to the highly exothermic composition, triggering the at least one reaction initiator thereby igniting the highly exothermic composition, and allowing the highly exothermic composition to achieve a post-ignition temperature sufficient to melt the breaching target substrate, forming a hole therethrough. |
| FILED | Thursday, July 23, 2020 |
| APPL NO | 16/937113 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 33/00 (20130101) Blasting F42D 1/043 (20130101) Original (OR) Class F42D 3/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287244 | Acker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE SYSTEMS INFORMATION AND ELECTRONIC SYSTEMS INTEGRATION INC. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Andrew N. Acker (Honolulu, Hawaii); Michael J. DeWeert (Kaneohe, Hawaii) |
| ABSTRACT | A shearography a system and method for regularizing phase resolved shearograms with an arctan regularization function to produce regularized phase resolved shearogram outputs is provided. The system and method of the present disclosure optimizes the processing of phase resolved shearography allowing interference fringe analysis techniques to be applied to the regularized phase resolved shearogram output results of the processing. |
| FILED | Friday, May 17, 2019 |
| APPL NO | 16/414871 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02098 (20130101) G01B 11/162 (20130101) Original (OR) Class Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 9/0215 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287328 | Soo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Indian Head, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by The Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Michael Soo (Alexandria, Virginia); John-Mark Clemenson, Jr. (Arlington, Virginia); Michael S. Kessler (LaPlata, Maryland); Adam W. Sims (Marbury, Maryland); Sam Goroshin (Montreal, Canada) |
| ABSTRACT | A thermocouple (TC) protection gauge may guard TCs from flying debris and fragments in an explosive environment or demanding commercial environments. The gauge may contain multiple co-located TCs. By using the protection gauge, the survivability of the TCs is significantly increased and allows for a longer time frame of data collection. Temperature data is acquired from multiple TCs that are experiencing approximately the same gas temperature and gas velocity. The temperature data may be used to reconstruct the real gas temperature of a dynamic event. Each of the TCs has a different diameter and therefore has a different time resolved temperature trace. The individual temperature traces may be used to extrapolate the real gas temperature using, for example, a reconstruction algorithm. |
| FILED | Thursday, August 27, 2020 |
| APPL NO | 16/873957 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 1/08 (20130101) Original (OR) Class G01K 1/026 (20130101) G01K 7/02 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/02 (20130101) H01L 35/30 (20130101) H01L 35/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287390 | Letourneau et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Reservoir Labs, Inc. (New York, New York) |
| ASSIGNEE(S) | Reservoir Labs, Inc. (New York, New York) |
| INVENTOR(S) | Pierre-David Letourneau (Long Island, New York); Mitchell Harris (New York, New York) |
| ABSTRACT | A technique for measuring properties of a material includes measuring the electromagnetic radiation scattered by one or more scattering points associated with the material, and adjusting the radiation according to the respective sensitivities of the scattering points to changes in material properties at that scattering point for several pairs of radiation sources and receivers. The material properties are determined using the updated measurements and corresponding simulated measurements. |
| FILED | Thursday, January 30, 2020 |
| APPL NO | 16/777189 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 22/00 (20130101) Original (OR) Class G01N 22/02 (20130101) G01N 23/00 (20130101) G01N 23/20 (20130101) G01N 27/04 (20130101) G01N 27/22 (20130101) G01N 27/72 (20130101) G01N 27/221 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/30 (20130101) Image Data Processing or Generation, in General G06T 11/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287430 | Delehanty et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | James B. Delehanty (Washington, District of Columbia); Michael H. Stewart (Springfield, Virginia); Okhil Nag (Alexandria, Virginia); Jeffrey R. Deschamps (Laurel, Maryland); Kimihiro Susumu (Alexandria, Virginia); Eunkeu Oh (Alexandria, Virginia); Lauren D. Field (College Park, Maryland); Alexander L. Efros (Annandale, Virginia); Alan L. Huston (Aldie, Virginia); Igor L. Medintz (Springfield, Virginia); Philip E. Dawson (San Diego, California) |
| ABSTRACT | A construct for detecting cellular membrane potential includes a nanoparticle operable as an electron donor; a modular peptide attached to the nanoparticle, the peptide comprising a nanoparticle association domain, a motif configured to mediate peptide insertion into the plasma membrane, and at least one attachment point for an electron acceptor positioned at a controlled distance from the nanoparticle; and an electron acceptor. The nanoparticle can be a quantum dot and the electron acceptor can be C60 fullerene. Emission correlates with cellular membrane potential. |
| FILED | Monday, June 08, 2020 |
| APPL NO | 16/894920 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 2319/035 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/588 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287508 | Zalalutdinov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Maxim K. Zalalutdinov (Silver Spring, Maryland); Douglas M. Photiadis (Falls Church, Virginia); Joseph A. Bucaro (Herndon, Virginia); Brian H. Houston (Fairfax, Virginia) |
| ABSTRACT | Systems and methods are provided for sensing acoustic signals using a floating base vector sensor. A vector sensor according to an embodiment of the present disclosure can be used to detect and characterize low frequency sound wave(s) in a viscous medium (e.g., air, water, etc.) by detecting a periodic motion of the media particles associated with the sound wave(s). The orientation of the particle velocity deduced from such measurements can provide information regarding the wave vector of the sound wave(s), can define the direction of arrival (DOA) for the acoustic signal, and can assist locating the source of the sound of interest. |
| FILED | Thursday, May 03, 2018 |
| APPL NO | 15/970369 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/28 (20130101) G01F 1/704 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 9/00 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 5/26 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/801 (20130101) G01S 3/8034 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287522 | Vazquez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | THE AEROSPACE CORPORATION (El Segundo, California) |
| INVENTOR(S) | George Vazquez (Woodland Park, Colorado); Christopher Bass (Colorado Springs, Colorado) |
| ABSTRACT | A single space platform with an optical telescope, a spectrometer, and/or a database of stored spectral information may be used to determine the range and/or velocity of natural or artificial resident space objects (RSOs). Relativistic Doppler shift measured from reflected solar photons and/or photons from other emitting source(s) provides information that the space platform can use to determine the relative velocity and the range rate. This information can then be used in combination with the right ascension and declination angles to perform differential correction and obtain an updated orbit. |
| FILED | Tuesday, October 16, 2018 |
| APPL NO | 16/161232 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/16 (20130101) G01S 7/40 (20130101) G01S 11/12 (20130101) G01S 13/32 (20130101) G01S 13/583 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287550 | Posey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Pamela Posey (Carriere, Mississippi); Richard Arthur Allard (Pass Christian, Mississippi); Julia Crout (Slidell, Louisiana); Gregg Arthur Jacobs (Slidell, Louisiana) |
| ABSTRACT | Embodiments relate to leads and polynyas forecasting. Initially observed ice forecast data is obtained for a geographic area of interest, which is then used to generate an ice grid based on the observed ice data, where the ice grid includes grid cells that map polar regions. At this stage, daily opening rates are determined based on the ice grid, where each daily opening rate indicates an opening speed of a corresponding ice event, and daily convergence strain rates are determined based on the ice grid, where each daily convergence strain rate indicates a convergence of the corresponding ice event. For each day, a daily opening rate is weighted and then adjusting by a daily convergence strain rate. A forecasted opening rate on a target date is determined based on the weighted, adjusted daily opening rates. Predicted openings of the polar region can be rendered based on the forecasted opening rate. |
| FILED | Monday, March 27, 2017 |
| APPL NO | 15/470373 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Meteorology G01W 1/00 (20130101) G01W 1/10 (20130101) Original (OR) Class G01W 2203/00 (20130101) Image Data Processing or Generation, in General G06T 11/60 (20130101) Technologies for Adaptation to Climate Change Y02A 90/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287569 | Soo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Indian Head, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Michael Soo (Alexandria, Virginia); Meghan Bash (Springfield, Virginia) |
| ABSTRACT | A high-speed imaging system for capturing images of flow created by initiation of energetic material includes a lens collector disposed in a protective shield. The protective shield helps protect the lens collector from damage due to the blast event. The lens connector is connected to an incoherent optical fiber bundle made of a bundle of coherent fiber bundles. The incoherent optical fiber bundle creates scrambled images that are relayed to a high-speed camera. A computer connected to the high-speed camera unscrambles the scrambled images to reproduce the images of the flow. |
| FILED | Wednesday, February 17, 2021 |
| APPL NO | 17/300028 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/06 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 5/22521 (20180801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287575 | Williams et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | US Gov't as represented by Secretary of Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Jeremiah C Williams (Dayton, Ohio); Hengky Chandrahalim (Beavercreek, Ohio) |
| ABSTRACT | A method is provided for fabricating a passive optical sensor on a tip of an optical fiber. The method includes perpendicularly cleaving a tip of an optical fiber and mounting the tip of the optical fiber in a specimen holder of a photosensitive polymer three-dimensional micromachining machine. The method includes forming a three-dimensional microscopic optical structure within the photosensitive polymer that comprises a two cavity Fabry-Perot Interferometer (FPI) having a hinged optical layer that is pivotally coupled to a suspended structure. The method includes removing an uncured portion of the photosensitive polymer using a solvent. The method includes depositing a reflective layer on a mirror surface of the hinged optical layer. The method includes positioning the pivotally hinged optical layer to a closed position with the suspended structure, aligning the mirror surface with the cleaved tip of the optical fiber. |
| FILED | Wednesday, April 21, 2021 |
| APPL NO | 17/236028 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 7/065 (20130101) Optical Elements, Systems, or Apparatus G02B 6/02033 (20130101) G02B 6/29358 (20130101) G02B 6/29359 (20130101) Original (OR) Class G02B 2006/12159 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287633 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Jonathan T. C. Liu (Seattle, Washington); Lindsey A. Barner (Seattle, Washington); Adam K. Glaser (Seattle, Washington) |
| ABSTRACT | Apparatuses, systems, and methods for solid immersion meniscus lenses (SIMlenses). An optical system may include a sample holder with a first side which supports a sample, and a second side opposite the first side. The second side of the sample holder may be in contact with an immersion fluid. Light passing between the sample and an objective lens may pass through the sample holder, immersion fluid, and a SIMlens positioned between the immersion fluid and objective. The SIMlens may have a first curved surface and a second curved surface, each of which may be shaped to match a wavefront of the light as it passes through the SIMlens. The immersion fluid, SIMlens, and environment containing the objective may all have different refractive indices. |
| FILED | Wednesday, June 23, 2021 |
| APPL NO | 17/356135 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/26 (20130101) G02B 21/0032 (20130101) G02B 21/33 (20130101) Original (OR) Class G02B 21/248 (20130101) G02B 21/367 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287642 | Valentine et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Jason G. Valentine (Nashville, Tennessee); Cary L. Pint (Nashville, Tennessee); Zachary J. Coppens (Nashville, Tennessee); Adam P. Cohn (Nashville, Tennessee) |
| ABSTRACT | A device according to one example of principles described herein may include a backplane, electrochemical actuator, and an optical resonator, wherein the electrochemical actuator is located between the backplane and optical resonator. Applied energy may be used to modify the volume of the electrochemical actuator material modifying the resonant/interferometric absorption, transmission, and reflection at visible and/or infrared frequencies. |
| FILED | Wednesday, September 19, 2018 |
| APPL NO | 16/135697 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 26/001 (20130101) Original (OR) Class G02B 26/085 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/21 (20130101) G02F 1/0123 (20130101) G02F 1/155 (20130101) G02F 1/213 (20210101) G02F 2001/1536 (20130101) G02F 2201/083 (20130101) G02F 2203/02 (20130101) G02F 2203/15 (20130101) G02F 2203/055 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287706 | Idehenre et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Ighodalo U. Idehenre (Tipp City, Ohio); Dean R. Evans (Beavercreek, Ohio) |
| ABSTRACT | A transparent device for use in optical applications, and methods for using and manufacturing the device are disclosed. The device generally requires several layers, including (i) a first layer comprising a transparent conductive oxide (such as indium tin oxide (ITO)), (ii) a second layer comprising a transparent semiconductor (e.g., a pn-heterojunction or a pn-homojunction), the second layer having a surface facing the first layer, (iii) a third layer comprising a liquid crystal (such as E7), the third layer having a surface facing the second layer, and (iv) a fourth layer comprising either a second transparent conductive oxide or a second transparent semiconductor, the fourth layer having a surface facing the third layer. When light illuminates a surface of the transparent metal oxide pn-heterojunction or transparent metal oxide pn-homojunction, it induces photoconductivity, modifying the surface charges. |
| FILED | Wednesday, December 16, 2020 |
| APPL NO | 17/123157 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/1354 (20130101) Original (OR) Class G02F 1/1357 (20210101) G02F 1/133784 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287819 | Blankespoor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Boston Dynamics, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | Boston Dynamics, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Kevin Blankespoor (Arlington, Massachusetts); Gabriel Nelson (Waltham, Massachusetts); Neil Neville (Waltham, Massachusetts) |
| ABSTRACT | A method for estimating a ground plane includes receiving a pose of a robotic device with respect to a gravity aligned reference frame, receiving one or more locations of one or more corresponding contact points between the robotic device and a ground surface, and determining a ground plane estimation of the ground surface based on the orientation of the robotic device with respect to the gravity aligned reference frame and the one or more locations of one or more corresponding contact points between the robotic device and the ground surface. The ground plane estimation includes a ground surface contour approximation. The method further includes determining a distance between a body of the robotic device and the determined ground plane estimation and causing adjustment of the pose of the robotic device with respect to the ground surface based on the determined distance and the determined ground plane estimation. |
| FILED | Tuesday, October 08, 2019 |
| APPL NO | 16/596006 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) B25J 9/1615 (20130101) B25J 9/1694 (20130101) B25J 9/1697 (20130101) Motor Vehicles; Trailers B62D 57/032 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0088 (20130101) Original (OR) Class G05D 1/0891 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11288090 | Cui et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ang Cui (New York, New York); Salvatore J. Stolfo (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Ang Cui (New York, New York); Salvatore J. Stolfo (New York, New York) |
| ABSTRACT | Methods, systems, and media for injecting code into embedded devices are provided. In accordance with some embodiments, methods for injecting code into embedded devices are provided, the methods comprising: embedding payload execution code into an embedded device; identifying program instructions in code of the embedded device into which jump instructions can be placed; inserting at least one jump instruction at an identified program instruction; allocating memory for storing an execution context of an injected payload; saving a context of the code of the embedded device to memory; loading and executing a payload context into a processor of the embedded device; determining when execution of the payload context is to be interrupted; and in response to determining that the execution of the payload context is to be interrupted, saving the payload context, restoring the context of the code of the embedded device, and continuing execution of the code of the embedded device. |
| FILED | Monday, August 20, 2018 |
| APPL NO | 16/105557 |
| ART UNIT | 2182 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 8/656 (20180201) G06F 9/48 (20130101) G06F 9/461 (20130101) Original (OR) Class G06F 9/44521 (20130101) G06F 21/00 (20130101) G06F 21/50 (20130101) G06F 21/51 (20130101) G06F 21/52 (20130101) G06F 21/64 (20130101) G06F 21/577 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11288320 | Beller et al. |
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| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Charles Beller (Baltimore, Maryland); Christopher Ackermann (Fairfax, Virginia); Kristen Summers (Takoma Park, Maryland); Rob High (Round Rock, Texas); David McQueeney (Yorktown Heights, New York) |
| ABSTRACT | Embodiments for identifying entities relevant to queries are provided. At least one query is received from a user. The at least one query is associated with at least one entity. Results of the at least one query are analyzed to identify related entities. The related entities are analyzed based on a relevancy score and an information enhancement score for each of the related entities to generate a ranking of the related entities. At least one of the related entities is provided to the user based on the ranking of the related entities. |
| FILED | Wednesday, June 05, 2019 |
| APPL NO | 16/432732 |
| ART UNIT | 2156 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/24578 (20190101) G06F 16/90324 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11288406 | Tran et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Nhut Tran (Natick, Massachusetts); J. Ryan Prince (Stow, Massachusetts); Brian Nugent (Acton, Massachusetts); Elliot Greenwald (Cambridge, Massachusetts) |
| ABSTRACT | An embodiment is directed to a hardware circuit for performing operations on data transmitted between a processor and memory. The hardware circuit includes a first interface communicatively coupled to the processor. The first interface configured to emulate a first protocol of the memory. The hardware circuit further includes a second interface communicatively coupled to the memory. The second interface configured to emulates a second protocol of the processor. The hardware circuit also includes hardware logic configured with a bi-directional path, such that each of the first and second interfaces is associated with a different direction of the bi-directional path. The bi-directional path is configured to execute an operation on data received at both the first interface and the second interface. |
| FILED | Friday, November 15, 2019 |
| APPL NO | 16/685678 |
| ART UNIT | 2435 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 9/45508 (20130101) G06F 21/79 (20130101) Original (OR) Class G06F 21/82 (20130101) G06F 21/602 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11288537 | McCloskey et al. |
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| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Scott McCloskey (Minneapolis, Minnesota); Keigo Hirakawa (Dayton, Ohio) |
| ABSTRACT | A system and process to determine whether a digital image has been manipulated involves determining expected locations of non-standard pixels in the digital image, and determining a feature for evaluating the non-standard pixels. The feature in pixels of the digital image that are located at the expected locations of non-standard pixels is then measured, and a statistical measure of the feature of pixels in the digital image that are located at the expected locations of non-standard pixels is evaluated. The digital image is assessed to determine a probability that the digital image includes a manipulated portion, based on the statistical measure. The system and process can also determine a make and model of an image sensing device via an examination of the non-standard pixels. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 16/785337 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00577 (20130101) G06K 9/4642 (20130101) G06K 9/6202 (20130101) G06K 9/6212 (20130101) Original (OR) Class G06K 9/6256 (20130101) G06K 9/6277 (20130101) G06K 2009/00583 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11288818 | Daniilidis et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Konstantinos Daniilidis (Wynnewood, Pennsylvania); Alex Zihao Zhu (Philadelphia, Pennsylvania) |
| ABSTRACT | A method for prediction of an indication of motion using input from an event-based camera includes receiving events captured by an event-based camera, wherein each of the events represents a location of a change in pixel intensity, a polarity of the change, and a time. The method further includes discretizing the events into time discretized event volumes, each of which contain events that occur within a specified time range. The method further includes providing the time discretized event volumes as input to an encoder-decoder neural network trained to predict an indication of motion using a loss function that measures quality of image deblurring; generating, using the neural network, a prediction of the indication of motion. The method further includes using the prediction of the indication of motion in a machine vision application. |
| FILED | Wednesday, February 19, 2020 |
| APPL NO | 16/795079 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/0472 (20130101) Image Data Processing or Generation, in General G06T 7/246 (20170101) Original (OR) Class G06T 2207/20084 (20130101) G06T 2207/30252 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11288856 | Lu et al. |
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| FUNDED BY |
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| APPLICANT(S) | INTELLIGENT FUSION TECHNOLOGY, INC. (Germantown, Maryland) |
| ASSIGNEE(S) | INTELLIGENT FUSION TECHNOLOGY, INC. (Germantown, Maryland) |
| INVENTOR(S) | Jingyang Lu (Germantown, Maryland); Yiran Xu (Germantown, Maryland); Dan Shen (Germantown, Maryland); Nichole Sullivan (Germantown, Maryland); Genshe Chen (Germantown, Maryland); Khanh Pham (Kirtland AFB, New Mexico); Erik Blasch (Arlington, Virginia) |
| ABSTRACT | The present disclosure provides a method for wave propagation prediction based on a 3D ray tracing engine and machine-learning based dominant ray selection. The method includes receiving, integrating, and processing input data. Integrating and processing the input data includes dividing a cone of the original millimeter wave (mmWave) into a plurality of sub cones; determining a contribution weight of rays coming from each sub cone to the received signal strength (RSS) at a receiving end of interest; and determining rays coming from one or more sub cones that have a total contribution weight to the RSS larger than a preset threshold value as dominant rays using a neural network obtained through a machine learning approach. The method further includes performing ray tracing based on the input data and the dominant rays to predict wave propagation. |
| FILED | Tuesday, November 05, 2019 |
| APPL NO | 16/674929 |
| ART UNIT | 2619 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 15/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11288977 | Howard et al. |
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| FUNDED BY |
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| APPLICANT(S) | HRL LABORATORIES, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Michael D. Howard (Westlake Village, California); Praveen K. Pilly (West Hills, California) |
| ABSTRACT | In an embodiment of the present invention, a method for generating a prediction of ability of a subject to perform a task in a future time step includes receiving performance data corresponding to a performance of the subject on the task; receiving a plurality of biometric inputs computed based on physiological data during the performance of the subject on the task; identifying a numerical relationship between the performance data and the plurality of biometric inputs; generating a modulation parameter for each of the plurality of biometric inputs based on the identified numerical relationship; loading a plurality of state variable inputs produced by a generic model of performance; and generate the prediction of ability to perform the task at the prediction time, generated by a trained performance predictor based on biometric inputs predicted based on the modulation parameters. |
| FILED | Friday, August 10, 2018 |
| APPL NO | 16/100921 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 20/00 (20190101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 9/08 (20130101) G09B 9/052 (20130101) G09B 19/0069 (20130101) G09B 19/165 (20130101) G09B 19/167 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11289175 | Srinivasa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL LABORATORIES LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Narayan Srinivasa (Oak Park, California); Qin Jiang (Park Oaks, California) |
| ABSTRACT | A method is disclosed. The method models a plurality of visual cortex neurons, models one or more connections between at least two visual cortex neurons in the plurality of visual cortex neurons, assigns synaptic weight value to at least one of the one or more connections, simulates application of one or more electrical signals to at least one visual cortex neuron in the plurality of visual cortex neurons, adjusts the synaptic weight value assigned to at least one of the one or more connection based on the one or more electrical signals, and generates an orientation map of the plurality of visual cortex neurons based on the adjusted synaptic weight values. |
| FILED | Friday, November 30, 2012 |
| APPL NO | 13/691130 |
| ART UNIT | 2124 — AI & Simulation/Modeling |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11289301 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Tiezhi Zhang (St. Louis, Missouri); Praneeth Kandlakunta (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Tiezhi Zhang (St. Louis, Missouri); Praneeth Kandlakunta (St. Louis, Missouri) |
| ABSTRACT | A multi-pixel x-ray source is provided. The x-ray source includes a plurality of transmission target assemblies. The transmission target assembly includes a tungsten target and a diamond substrate. The substrate includes a first transmission surface and a second transmission surface opposite first transmission surface. The substrate further includes a first side surface and a second side surface disposed between the first and second transmission surfaces. The target covers the first transmission surface of the substrate. The transmission target assembly further includes a base. The base surrounds the first and second side surfaces of substrate, exposing a collimator surface of the second transmission surface and the target. The transmission target assembly is configured to transmit x-ray generated by the target through the target and the substrate. |
| FILED | Friday, November 06, 2020 |
| APPL NO | 17/091744 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Electric Digital Data Processing G06F 30/20 (20200101) Electric Discharge Tubes or Discharge Lamps H01J 35/12 (20130101) H01J 35/116 (20190501) Original (OR) Class H01J 2235/081 (20130101) H01J 2235/083 (20130101) X-ray Technique H05G 1/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11289444 | Esler et al. |
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| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | David Richard Esler (Gloversville, New York); Nancy Cecelia Stoffel (Niskayuna, New York) |
| ABSTRACT | A sensor assembly includes a die substrate and a metalized layer formed on the die substrate. The metalized layer is formed of a first metal material and includes a bonding pad to facilitate electrically coupling the sensor assembly to a sensor system. A remetalized bump is formed on the bonding pad of a second metal material and is electrically coupled to the metalized layer. An adhesive is applied to the remetalized bump and facilitates mechanically coupling the sensor assembly to the sensor system. |
| FILED | Friday, December 13, 2019 |
| APPL NO | 16/713437 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 7/0006 (20130101) B81B 2207/098 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00301 (20130101) B81C 2203/032 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 24/05 (20130101) H01L 24/08 (20130101) H01L 24/11 (20130101) H01L 24/13 (20130101) H01L 24/32 (20130101) H01L 24/73 (20130101) Original (OR) Class H01L 24/92 (20130101) H01L 41/0475 (20130101) H01L 2224/05124 (20130101) H01L 2224/05686 (20130101) H01L 2224/9211 (20130101) H01L 2224/13124 (20130101) H01L 2224/13144 (20130101) H01L 2224/13147 (20130101) H01L 2224/13164 (20130101) H01L 2224/13169 (20130101) H01L 2224/16157 (20130101) H01L 2224/16227 (20130101) H01L 2224/32157 (20130101) H01L 2224/32227 (20130101) H01L 2224/73104 (20130101) H01L 2224/73204 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11289757 | Nemanick et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | THE AEROSPACE CORPORATION (El Segundo, California) |
| INVENTOR(S) | Eric Joseph Nemanick (Santa Monica, California); Henry Helvajian (Pasadena, California); Brian Shen (Hawthorne, California) |
| ABSTRACT | Describe herein is an energy storage system that includes a battery and a heat source. The battery harvests waste heat from the heat source to keep itself warm while storing electrical energy generated from a heat to energy transforming source. If the heat source is radioactive (e.g. radioisotope decay) a radiation hard battery is intimately connected to a waste heat source. The radiation hard battery harvests waste heat from the heat source to warm itself and to shield the radiation. |
| FILED | Wednesday, October 16, 2019 |
| APPL NO | 16/654105 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/32 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/46 (20130101) H01M 10/66 (20150401) Original (OR) Class H01M 10/0525 (20130101) H01M 10/0562 (20130101) H01M 10/615 (20150401) H01M 10/653 (20150401) H01M 10/659 (20150401) H01M 2300/0074 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11290181 | Meyers et al. |
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| FUNDED BY |
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| APPLICANT(S) | U.S. Army Combat Capabilities Development Command, Army Research Labortary (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Ronald E. Meyers (Columbia, Maryland); Keith S. Deacon (Columbia, Maryland) |
| ABSTRACT | Measurement of entangled photon quantum wavefunction properties is vital for studying the fundamentals of entanglement and for future applications in quantum communications, quantum metrology, quantum sensing and imaging. Despite its importance, measuring the wavefunction is difficult, particularly in pulsed and other systems with system features and wavefunctions changing in space and time. This invention uses ghost imaging techniques to directly measure the entangled photon wavefunction of pulsed origin temporal and polarization entangled photons. The invention may be used to improve wavefunction quality after propagation through turbulent or scattering media. |
| FILED | Thursday, March 18, 2021 |
| APPL NO | 17/205117 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Transmission H04B 10/70 (20130101) H04B 10/079 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11290212 | Hutchinson et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Meredith N. Hutchinson (Washington, District of Columbia); Jonathan M. Nichols (Crofton, Maryland); Gustavo K. Rohde (Crozet, Virginia); Nicole Menkart (Potomac, Maryland); Geoffrey A. Cranch (Fairfax Station, Virginia) |
| ABSTRACT | Methods, apparatuses, and systems for calculating time delays by a Wasserstein approach are provided. A plurality of signals are recorded by a plurality of sensors (three or more), respectively, and received at a controller. The plurality of signals recorded by the plurality of sensors are generated in response to a signal emitted by a source. The plurality of signals are converted into a plurality of probability density functions. A cumulative distribution transform for each of the plurality of probability density functions is calculated. A time delay for each unique pair of the plurality of sensors is calculated by minimizing a Wasserstein distance between two cumulative distribution transforms corresponding to the unique pair of the plurality of sensors. |
| FILED | Thursday, June 18, 2020 |
| APPL NO | 16/905842 |
| ART UNIT | 2473 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0631 (20130101) H04L 1/0681 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11290338 | DeCleene et al. |
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| FUNDED BY |
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| APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire); University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Brian DeCleene (North Reading, Massachusetts); Anirudh Sabnis (Amherst, Massachusetts); Ramesh K. Sitaraman (Amherst, Massachusetts); Donald Towsley (Amherst, Massachusetts); Paul Vines (Leesburg, Virginia) |
| ABSTRACT | Techniques and architecture are disclosed for inferring a unified topological model of a hidden topology comprising dispersing data packets from a source to at least one receiver, and collecting individual end-to-end packet statistics; collecting aggregate end-to-end statistical measurements between a plurality of enclaves situated at an edge of an unknown network; identifying shared path correlations relating to shared links traversed between at least one root enclave and one or more leaf enclaves; constructing topological metrics as a directed tree corresponding to shared path correlations; inferring a unified topological model and routing paths of the unknown network based on the plurality of topological metrics collected by the plurality of enclaves; validating consistency between the subsequent end-to-end statistical measurements and the unified topological model of the hidden topology; and updating the inferred unified topological model of the hidden topology in accordance with observed inconsistencies. |
| FILED | Monday, June 08, 2020 |
| APPL NO | 16/895738 |
| ART UNIT | 2443 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/12 (20130101) Original (OR) Class H04L 41/16 (20130101) H04L 41/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11290426 | Roy |
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| FUNDED BY |
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| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Radhika Roy (Howell, New Jersey) |
| ABSTRACT | Various embodiments that pertain to an enterprise network that employs a block chain portion and a non-block chain portion. For a single transaction, a header of the transaction can be sent over the block chain network and the non-header of the transaction can be sent over the non-block chain network. A hash-based cuckoo filter can be used for communication of the header along the block chain network. |
| FILED | Monday, June 17, 2019 |
| APPL NO | 16/442627 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0643 (20130101) H04L 9/3242 (20130101) H04L 63/0414 (20130101) Original (OR) Class H04L 63/0428 (20130101) H04L 2209/38 (20130101) H04L 2463/041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11290498 | Soroush et al. |
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| FUNDED BY |
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| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Hamed Soroush (San Jose, California); Shantanu Rane (Menlo Park, California) |
| ABSTRACT | The system generates evidence of a recommended configuration for a distributed system based on a plurality of configuration parameters. The system displays, on a screen of a user device, the evidence, which includes a list of configuration parameters, including a name, a current value, and a recommended value for a respective configuration parameter. The recommended value is obtained based on a strategy for optimizing security, functionality, or both. The system further displays interactive elements which allow the user to: view a resolution of a pair of mutually incompatible constraints resulting in the recommended value for the respective configuration parameter, wherein the resolution includes a name of the configuration parameter removed from the list and a reason for the removal; and view information associated with each of the pair of mutually incompatible constraints, wherein the information includes a name, a goal, a security impact, and a description of the constraint. |
| FILED | Thursday, July 09, 2020 |
| APPL NO | 16/925063 |
| ART UNIT | 2435 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/252 (20190101) G06F 21/577 (20130101) G06F 2221/034 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 5/04 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/205 (20130101) Original (OR) Class H04L 63/1433 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11284858 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Lianjie Huang (Los Alamos, New Mexico); Kai Gao (Los Alamos, New Mexico); Yunsong Huang (Los Alamos, New Mexico) |
| ABSTRACT | A method for plane-wave or fan-beam ultrasound tomography includes: controlling, by a processor, a multi-channel ultrasound array controller to control a linear ultrasound transducer array to emit plane-wave or fan-beam ultrasound into a biological tissue, the linear ultrasound transducer array including a plurality of transducers; receiving, by the processor, plane-wave or fan-beam ultrasound waveform data from the transducers, the plane-wave or fan-beam ultrasound waveform data including reflections of the plane-wave or fan-beam ultrasound from the biological tissue; computing, by the processor, a synthetic ultrasound-waveform inversion from the received plane-wave or fan-beam ultrasound waveform data; and computing, by the processor, an image of the biological tissue from the synthetic ultrasound-waveform inversion. |
| FILED | Tuesday, July 02, 2019 |
| APPL NO | 16/460899 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/08 (20130101) A61B 8/13 (20130101) Original (OR) Class A61B 8/4483 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/0672 (20130101) G01N 2291/02466 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285165 | DeNardo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Sally J. DeNardo (El Macero, California); Gerald L. DeNardo (El Macero, California); Rodney L. Balhorn (Livermore, California) |
| ABSTRACT | This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use of antibodies. SHALs typically comprise a multiplicity of ligands that each bind different region son the target molecule. The ligands are joined directly or through a linker thereby forming a polydentate moiety that typically binds the target molecule with high selectivity and avidity. |
| FILED | Wednesday, April 08, 2020 |
| APPL NO | 16/843783 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/675 (20130101) Original (OR) Class A61K 47/55 (20170801) A61K 47/60 (20170801) A61K 47/64 (20170801) A61K 47/545 (20170801) A61K 47/645 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285430 | Lail et al. |
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| FUNDED BY |
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| APPLICANT(S) | Research Triangle Institute (Research Triangle Park, North Carolina) |
| ASSIGNEE(S) | Research Triangle Institute (Research Triangle Park, North Carolina) |
| INVENTOR(S) | Marty Lail (Raleigh, North Carolina); Aravind Villava Rayer Rabindran (Morrisville, North Carolina); Samuel John Thompson (Chapel Hill, North Carolina) |
| ABSTRACT | The disclosure provides methods and systems for decreasing nitrosamine content, e.g., in the context of non-aqueous solvent systems. It includes a method including receiving a non-aqueous solvent system and contacting the non-aqueous solvent system with a composition including one or more alkoxides to give a treated solvent system having a nitrosamine content that is lower than the starting nitrosamine content. Similarly, it includes a system including a first unit configured to remove undesirable components from a gas stream; a second unit holding a composition including one or more alkoxides, and a conduit to connect these units. |
| FILED | Tuesday, January 21, 2020 |
| APPL NO | 16/748111 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/18 (20130101) B01D 53/1425 (20130101) Original (OR) Class B01D 53/1475 (20130101) B01D 2252/204 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285534 | Yacout et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Abdellatif M. Yacout (Naperville, Illinois); Sumit Bhattacharya (Darien, Illinois) |
| ABSTRACT | A method loading powder into a mold can include immersing the mold comprising one or more microchannels into a suspension comprising the powder and a surfactant suspended in a dispersant, wherein the powder comprises particles having an average particle size of less than 100 μm, wherein the mold is substantially entirely covered by the suspension; heating the suspension having the mold immersed therein under a temperature condition suitable to lower the stability of the particles of the powder in the suspension such that the particles settle out of solution and into the one or more microchannels; and applying an ultrasonic wave to the heated suspension to further settle the particles of the powder into the one or more microchannels thereby filling the one or more microchannels of the mold with the powder. |
| FILED | Friday, September 28, 2018 |
| APPL NO | 16/147347 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0022 (20130101) B22F 1/0074 (20130101) B22F 3/004 (20130101) Original (OR) Class B22F 3/093 (20130101) B22F 2202/01 (20130101) B22F 2301/10 (20130101) B22F 2301/15 (20130101) B22F 2302/253 (20130101) B22F 2304/10 (20130101) B22F 2304/054 (20130101) B22F 2304/056 (20130101) B22F 2304/058 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 43/01 (20130101) C01G 56/00 (20130101) Alloys C22C 28/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285635 | Terrani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Kurt A. Terrani (Knoxville, Tennessee); Michael P. Trammell (Knoxville, Tennessee); Brian C. Jolly (Knoxville, Tennessee) |
| ABSTRACT | A method for the manufacture of a three-dimensional object using a refractory matrix material is provided. The method includes the additive manufacture of a green body from a powder-based refractory matrix material followed by densification via chemical vapor infiltration (CVI). The refractory matrix material can be a refractory ceramic (e.g., silicon carbide, zirconium carbide, or graphite) or a refractory metal (e.g., molybdenum or tungsten). In one embodiment, the matrix material is deposited according to a binder-jet printing process to produce a green body having a complex geometry. The CVI process increases its density, provides a hermetic seal, and yields an object with mechanical integrity. The residual binder content dissociates and is removed from the green body prior to the start of the CVI process as temperatures increase in the CVI reactor. The CVI process selective deposits a fully dense coating on all internal and external surfaces of the finished object. |
| FILED | Wednesday, July 31, 2019 |
| APPL NO | 16/527317 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1007 (20130101) B22F 3/1021 (20130101) B22F 7/02 (20130101) B22F 2301/20 (20130101) B22F 2302/105 (20130101) B22F 2998/10 (20130101) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Original (OR) Class Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/52 (20130101) C04B 35/573 (20130101) C04B 35/5622 (20130101) C04B 2235/77 (20130101) C04B 2235/614 (20130101) Nuclear Reactors G21C 3/324 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285704 | Stadermann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC. (Livermore, California) |
| INVENTOR(S) | Michael Stadermann (Pleasanton, California); Patrick Campbell (Oakland, California); Philip E. Miller (Livermore, California); Chantel Aracne-Ruddle (Livermore, California); Sung Ho Kim (Livermore, California); Francisco J. Espinosa-Loza (Bellevue, Washington) |
| ABSTRACT | According to one embodiment, a product includes a composite film comprising a polymer layer directly adjacent a graphene layer. According to another embodiment, a process includes layering a graphene layer onto a polymer layer to form a composite film. |
| FILED | Thursday, September 07, 2017 |
| APPL NO | 15/698473 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 99/005 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 9/007 (20130101) B32B 18/00 (20130101) B32B 27/06 (20130101) Original (OR) Class B32B 37/14 (20130101) B32B 2309/105 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/184 (20170801) C01B 32/194 (20170801) Technical Subjects Covered by Former US Classification Y10T 428/30 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286277 | Tezcan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Faik Akif Tezcan (La Jolla, California); Yuta Suzuki (Tsuruoka, Japan) |
| ABSTRACT | Polypeptide assemblies and building blocks and methods for making them are provided. |
| FILED | Thursday, July 14, 2016 |
| APPL NO | 15/746789 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 1/306 (20130101) C07K 2/00 (20130101) Original (OR) Class C07K 2319/00 (20130101) C07K 2319/21 (20130101) C07K 2319/60 (20130101) C07K 2319/735 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/88 (20130101) C12N 15/1031 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286337 | Bae et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Chulsung Bae (Cohoes, New York); Woo-Hyung Lee (Siheung-Si, South Korea) |
| ABSTRACT | Embodiments of the invention relate to a novel class of polymers with superior mechanical properties and chemical stability, as compared to known polymers. These polymers are particularly well suited for use in anion exchange membranes (AEMs), including those employed in fuel cells. Novel methods for the manufacture of these polymers are also described. |
| FILED | Wednesday, August 28, 2019 |
| APPL NO | 16/553965 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 29/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 10/00 (20130101) C08G 61/02 (20130101) Original (OR) Class C08G 2261/20 (20130101) C08G 2261/45 (20130101) C08G 2261/124 (20130101) C08G 2261/146 (20130101) C08G 2261/312 (20130101) C08G 2261/332 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/14 (20130101) C09D 165/00 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 13/08 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/1004 (20130101) H01M 8/1039 (20130101) H01M 8/1072 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286340 | Miyake et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| INVENTOR(S) | Garret Miyake (Fort Collins, Colorado); Ryan M. Pearson (Berkeley, California); Matthew D. Ryan (Berkeley, California) |
| ABSTRACT | The present invention provides efficient processes for preparing brush polymers. In general, the process comprises three distinct reaction steps utilizing two separate catalysts. In the first step, the initiating compound comprising norbornene is contacted with a silane in the presence of a catalyst, thereby forming a silated intermediate. This silated intermediate is then contacted with a monomer in the presence of a catalyst via Group Transfer Polymerization (GTP). The resulting compound from GTP is contacted with a ring opening metathesis polymerization (ROMP) catalyst to prepare the brush polymer. Surprisingly, the brush polymers obtained from the above process are accessed in an efficient and rapid GTP methodology as compared to prior methods. |
| FILED | Wednesday, January 29, 2020 |
| APPL NO | 16/775755 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/124 (20130101) C08G 61/125 (20130101) Original (OR) Class C08G 2261/128 (20130101) C08G 2261/136 (20130101) C08G 2261/418 (20130101) C08G 2261/1426 (20130101) C08G 2261/1432 (20130101) C08G 2261/3241 (20130101) C08G 2261/3245 (20130101) C08G 2261/3324 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286419 | Cozzan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Clayton J. Cozzan (Goleta, California); Steven P. DenBaars (Goleta, California); Ram Seshadri (Goleta, California) |
| ABSTRACT | A method for fabricating a composite useful in a white light emitting device, includes mixing a phosphor and a filler to form a mixture; sintering the mixture (e.g., using spark plasma sintering) to form a composite; and annealing the composite to reduce oxygen vacancies and improve optical properties of the composite. Also disclosed is a white light emitting device including a laser diode or light emitting diode optically pumping the phosphor in the composite to produce white light. The composite fabricated using the method (and having. e.g., at most 50% phosphor by weight) can (1) reduce an operating temperature of the phosphor by 55 degrees, (2) increase an external quantum efficiency (e.g., by at least 15%) of the white light emitting device, and (3) result in color points and quality of the white light that is equal to or improved, as compared to without the filler. |
| FILED | Monday, July 31, 2017 |
| APPL NO | 16/320295 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/10 (20130101) C04B 35/44 (20130101) C04B 35/117 (20130101) C04B 35/645 (20130101) C04B 2235/77 (20130101) C04B 2235/80 (20130101) C04B 2235/662 (20130101) C04B 2235/664 (20130101) C04B 2235/666 (20130101) C04B 2235/3217 (20130101) C04B 2235/3222 (20130101) C04B 2235/3225 (20130101) C04B 2235/3229 (20130101) C04B 2235/6562 (20130101) C04B 2235/6565 (20130101) C04B 2235/6567 (20130101) C04B 2235/6581 (20130101) C04B 2235/6582 (20130101) C04B 2235/9607 (20130101) C04B 2235/9646 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/02 (20130101) Original (OR) Class C09K 11/7774 (20130101) Non-electric Light Sources Using Luminescence; Light Sources Using Electrochemiluminescence; Light Sources Using Charges of Combustible Material; Light Sources Using Semiconductor Devices as Light-generating Elements; Light Sources Not Otherwise Provided for F21K 9/64 (20160801) F21K 9/68 (20160801) Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to the Form or the Kind of the Light Sources or of the Colour of the Light Emitted F21Y 2115/10 (20160801) F21Y 2115/30 (20160801) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/055 (20130101) H01L 33/501 (20130101) H01L 33/502 (20130101) H01L 2933/0041 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 33/14 (20130101) H05B 33/20 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 20/00 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286432 | Timko et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Worcester Polytechnic Institute (Worcester, Massachusetts) |
| ASSIGNEE(S) | Worcester Polytechnic Institute (Worcester, Massachusetts) |
| INVENTOR(S) | Michael T. Timko (Arlington, Massachusetts); Geoffrey A. Tompsett (Shrewsbury, Massachusetts); Alex R. Maag (Ithaca, New York) |
| ABSTRACT | Catalyst composition and parameters for catalytic hydrothermal liquefaction of biomass to bio-oil fuels target municipal solid waste (MSW) rather than lignin rich plant waste typically sought for bio-oil production. An HTL (Hydrothermal Liquefaction) reactor generates bio-fuel from municipal solid waste (MSW), including receiving, in the HTL reactor, non-lignin based waste from a municipal processing stream, and adding a solvent for extracting sugars from green waste components of the municipal processing stream. The reactor extracts a liquid from the received waste, and converts water soluble products in the liquid into oil soluble products via C—C (carbon-to-carbon) coupling reactions. A catalyst added to the resulting aqueous stream recovers a beneficial oil product, and is optimized by tuning acid and base sites on the solid catalyst. |
| FILED | Thursday, September 26, 2019 |
| APPL NO | 16/583582 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/002 (20130101) B01J 23/10 (20130101) B01J 37/0201 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 53/06 (20130101) Original (OR) Class Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286494 | Benning et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Christoph Benning (East Lansing, Michigan); Kun Wang (East Lansing, Michigan) |
| ABSTRACT | Described herein are transgenic plants with increased oil content that exhibit enhanced expression of plastid-specific lipases (e.g., PLIP1). The manufacture of lipids can be enhanced by expression of FAD4. |
| FILED | Thursday, March 29, 2018 |
| APPL NO | 16/498663 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/20 (20130101) C12N 9/0071 (20130101) C12N 15/8247 (20130101) Original (OR) Class Enzymes C12Y 114/19 (20130101) C12Y 301/01032 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286783 | Martin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Thomas J. Martin (East Hampton, Connecticut); John E. Holowczak (South Windsor, Connecticut); Matthew B. Kennedy (Vernon, Connecticut); Paul F. Croteau (Columbia, Connecticut); Paul Attridge (Colchester, Connecticut) |
| ABSTRACT | An airfoil includes an airfoil section that has an airfoil wall that surrounds a cavity. The airfoil wall includes an exterior monolithic ceramic shell and an interior CMC liner that has CMC plies. An outermost ply of the CMC plies forms tabs that are raised from an underlying ply so as to define a slot. The exterior monolithic ceramic shell includes an underlapping shell piece and an overlapping shell piece. The underlapping shell piece has a portion disposed in the slot and bonded with the tabs. The overlapping shell piece extends over the tabs and is bonded to the tabs. There are channels bounded by adjacent ones of the tabs, the underlapping shell piece, and the overlapping shell piece. Channel orifices through the CMC liner connect the cavity and the channels. |
| FILED | Monday, April 27, 2020 |
| APPL NO | 16/859198 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/147 (20130101) Original (OR) Class F01D 5/282 (20130101) F01D 5/284 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2300/6033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287079 | Biswas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Kaushik Biswas (Knoxville, Tennessee); Pengfei Cao (Knoxville, Tennessee); Tomonori Saito (Knoxville, Tennessee) |
| ABSTRACT | A self-healing vacuum insulation panel and a method of manufacture are provided. The vacuum insulation panel includes a self-healing, multi-layer barrier film including a separator between a curing agent and a curable resin. Upon damage to the separator, the curing agent penetrates the separator due to a pressure differential across the barrier film and reacts with the curable resin to seal any cuts or punctures. The curing agent and the curable resin can be selected to have long term stability and a short reaction time with no need for external stimuli. As a result, the multi-layer barrier film can retain the internal vacuum and maintain a desirably low thermal conductivity using low-cost, commercially available epoxies and curing agents. |
| FILED | Friday, January 17, 2020 |
| APPL NO | 16/746149 |
| ART UNIT | 1781 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/04 (20130101) B32B 5/16 (20130101) B32B 5/18 (20130101) B32B 27/12 (20130101) B32B 27/36 (20130101) B32B 27/065 (20130101) B32B 37/185 (20130101) B32B 38/1858 (20130101) B32B 2250/40 (20130101) B32B 2255/10 (20130101) B32B 2255/26 (20130101) B32B 2255/28 (20130101) B32B 2255/205 (20130101) B32B 2266/06 (20130101) B32B 2307/304 (20130101) B32B 2307/762 (20130101) B32B 2307/7246 (20130101) B32B 2367/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/66 (20130101) C08G 59/4042 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 167/02 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 59/065 (20130101) Original (OR) Class Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for F25D 23/065 (20130101) F25D 2201/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287134 | Berry |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Jonathan Dwight Berry (Simpsonville, South Carolina) |
| ABSTRACT | A combustor may include a combustor liner and flow sleeve. A high pressure air cools an outer surface of the combustor liner via openings in the flow sleeve, creating a lower pressure air in an annulus between the combustor liner and the flow sleeve. A first fuel nozzle is positioned at a primary combustion zone, and a second fuel nozzle is positioned at a secondary combustion zone of the liner. A fuel source is configured to deliver a fuel to the fuel nozzles. The fuel nozzles produce a premixture of high pressure air and the fuel, and produce a mixture of the premixture and the lower pressure air, prior to introducing the mixture to a respective primary or secondary combustion zone of the combustor. The combustor provides improved fuel premixing and is fuel flexible, and reduces pressure drop requirements. The combustor is usable in a can, annular, or segmented annular combustor assembly. |
| FILED | Tuesday, December 31, 2019 |
| APPL NO | 16/731207 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/005 (20130101) F23R 3/10 (20130101) F23R 3/26 (20130101) F23R 3/36 (20130101) F23R 3/286 (20130101) F23R 3/346 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287358 | Nath et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Pulak Nath (Los Alamos, New Mexico); Jackson Henry McFall (Los Alamos, New Mexico); Dylan Chance Purcell (Los Alamos, New Mexico); Jen-Huang Huang (Los Alamos, New Mexico) |
| ABSTRACT | Devices that include a liquid chamber including at least two ports, wherein the opening of a first port is larger than the opening of a second port, an air chamber including at least one port, and a membrane located between the liquid chamber and the air chamber, and a pressure sensor coupled to the port in the air chamber are provided. Systems including the disclosed devices are also provided. The systems include liquid in the liquid chamber of the device. Methods of using the devices and systems include measuring one or more properties of a liquid by flowing the liquid through the liquid chamber of the system and measuring the pressure produced due to the difference in size of the ports in the liquid chamber. |
| FILED | Monday, August 12, 2019 |
| APPL NO | 16/538561 |
| ART UNIT | 1799 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/14 (20130101) G01N 11/08 (20130101) Original (OR) Class G01N 33/5044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287362 | Kaduchak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Gregory Kaduchak (Los Alamos, New Mexico); Michael D. Ward (Los Alamos, New Mexico) |
| ABSTRACT | The present invention is a method and apparatus for acoustically manipulating one or more particles. |
| FILED | Wednesday, September 18, 2019 |
| APPL NO | 16/574745 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/0636 (20130101) B01L 2200/0652 (20130101) B01L 2300/0838 (20130101) B01L 2300/0864 (20130101) B01L 2400/0439 (20130101) B01L 2400/0487 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1404 (20130101) Original (OR) Class G01N 15/1459 (20130101) G01N 15/1463 (20130101) G01N 29/14 (20130101) G01N 33/4833 (20130101) G01N 33/48735 (20130101) G01N 2001/4094 (20130101) G01N 2015/142 (20130101) G01N 2015/149 (20130101) G01N 2015/1081 (20130101) G01N 2015/1415 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287363 | Kaduchak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Gregory Kaduchak (Los Alamos, New Mexico); Michael D. Ward (Los Alamos, New Mexico) |
| ABSTRACT | The present invention provides systems and methods for using acoustic radiation pressure to fractionate particles within a fluid. |
| FILED | Tuesday, October 15, 2019 |
| APPL NO | 16/653020 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/0636 (20130101) B01L 2200/0652 (20130101) B01L 2300/0838 (20130101) B01L 2300/0864 (20130101) B01L 2400/0439 (20130101) B01L 2400/0487 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1404 (20130101) Original (OR) Class G01N 15/1459 (20130101) G01N 15/1463 (20130101) G01N 29/14 (20130101) G01N 33/4833 (20130101) G01N 33/48735 (20130101) G01N 2001/4094 (20130101) G01N 2015/142 (20130101) G01N 2015/149 (20130101) G01N 2015/1081 (20130101) G01N 2015/1415 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287381 | Gu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Lianhong Gu (Oak Ridge, Tennessee); Jeffrey S. Riggs (LaFollette, Tennessee) |
| ABSTRACT | A chlorophyll fluorescence measuring system having at least one spectrometer coupled to a data logger. The data logger provides direct control of the spectrometer and includes on-board memory for storage of target and reference spectrum data obtained by the spectrometer. The data logger may be coupled to an external computer that receives and analyzes target and reference spectrum data to determine SIF using a spectral fitting algorithm. The system may include a spectrometer aiming system coupled to and controlled by the data logger. The system may also include one or more environmental sensors configured to measure environment variables. The environmental sensors may be coupled to the data logger for control and data storage. The environmental data may be communicated to the external computer for use in the spectral fitting algorithm. The data logger may be connected to a network for remote monitoring and control. |
| FILED | Friday, June 30, 2017 |
| APPL NO | 15/638473 |
| ART UNIT | 2864 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6486 (20130101) Original (OR) Class G01N 2021/635 (20130101) G01N 2021/6417 (20130101) G01N 2021/6484 (20130101) G01N 2021/8466 (20130101) G01N 2201/08 (20130101) G01N 2201/13 (20130101) G01N 2201/0231 (20130101) G01N 2201/0238 (20130101) G01N 2201/0616 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287408 | Karp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jason Harris Karp (Niskayuna, New York); William Albert Challener (Glenville, New York) |
| ASSIGNEE(S) | BAKER HUGHES, A GE COMPANY, LLC (Houston, Texas) |
| INVENTOR(S) | Jason Harris Karp (Niskayuna, New York); William Albert Challener (Glenville, New York) |
| ABSTRACT | A gas detector sensor node includes a first sensor conductor having a terminal end, a second sensor conductor including an end section, and a coupler joining the terminal end of the first sensor conductor with the end section of the second sensor conductor. The coupler is permeable to gas. |
| FILED | Tuesday, April 30, 2019 |
| APPL NO | 16/398665 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/0036 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 6/12 (20130101) G02B 6/26 (20130101) G02B 6/02328 (20130101) G02B 6/02361 (20130101) G02B 6/3833 (20130101) G02B 2006/12102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287463 | Karin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Todd Karin (Los Gatos, California); Peter Kiesel (Palo Alto, California); Ajay Raghavan (Mountain View, California) |
| ABSTRACT | A partial discharge (PD) transducer that includes a PD sensor configured to sense a PD event of an electrical system. At least one light emitting device (LED) is arranged in series with the PD sensor. The LED is configured to receive the electrical sensor signal from the PD sensor and to generate a light signal in response to the electrical sensor signal. |
| FILED | Friday, December 28, 2018 |
| APPL NO | 16/235747 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 15/16 (20130101) G01R 15/22 (20130101) G01R 19/0084 (20130101) G01R 31/1218 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287481 | Weiss et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Xilectric, Inc. (Fall River, Massachusetts) |
| ASSIGNEE(S) | Xilectric, Inc. (Fall River, Massachusetts) |
| INVENTOR(S) | Steven E. Weiss (Auburndale, Massachusetts); Charles R. Lemay (Portsmouth, New Hampshire); Andrew Ferencz (Southborough, Massachusetts) |
| ABSTRACT | Systems, devices, and methods of diagnosing an electrochemical cell using cyclic coulometry are discussed. An exemplary battery diagnostic system comprises a current generator to generate symmetric charge current and discharge current to excite an electrochemical cell, and a cyclic coulometer to evaluate performance of the electrochemical cell. The cyclic coulometer can adjust at least one of a charge time for applying the charge current, or a discharge time for applying the discharge current, to keep a monitored cell voltage toward a specific setpoint. The adjustment of charge or discharge time can be achieved by changing a current switch timing for reversing current from a first to a second current direction. The cyclic coulometer measures one or more electrical parameters during the charge or discharge cycle, and generates a performance metric using the measured electrical parameters. |
| FILED | Wednesday, June 05, 2019 |
| APPL NO | 16/432331 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/367 (20190101) G01R 31/388 (20190101) G01R 31/3842 (20190101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/484 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/008 (20130101) H02J 7/0078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287506 | Rouse et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Jerry W. Rouse (Albuquerque, New Mexico); Daniel Bowman (Albuquerque, New Mexico); Timothy Walsh (West Lafayette, Indiana) |
| ABSTRACT | A method and apparatus for determining a direction of infrasound. Infrasound is received by a directional infrasound sensor comprising a plurality of channels and a plurality of sensor devices. Each channel in the plurality of channels comprises a single opening at a first end of the channel and a closed end opposite the opening. The opening of each channel in the plurality of channels is pointed in a different direction from the opening of each other channel in the plurality of channels. The plurality of sensor devices includes a sensor device at the closed end of each channel in the plurality of channels. Each sensor device in the plurality of sensor devices is configured to generate a sensor signal in response to pressure. The sensor signals generated by the plurality of sensor devices are processed to determine the direction of the infrasound received by the directional infrasound sensor. |
| FILED | Friday, June 05, 2020 |
| APPL NO | 16/893675 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/801 (20130101) G01S 3/8006 (20130101) Original (OR) Class G01S 3/8034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287536 | Howell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Stephen W. Howell (Bloomington, Indiana); David W. Peters (Albuquerque, New Mexico); Thomas Edwin Beechem, III (Albuquerque, New Mexico); Isaac Ruiz (Albuquerque, New Mexico); Richard Karl Harrison (Albuquerque, New Mexico); Jeffrey B. Martin (Albuquerque, New Mexico) |
| ABSTRACT | A radiation field is detected or imaged using one or more junction devices in which a two-dimensional conductor layer is capacitively coupled to a semiconductor absorber layer. In the junction devices, pixel-level amplification and read-out are accomplished through the photogating of the devices by absorption within the absorber layer while it is in a state of deep depletion. When the two-dimensional conductor is graphene, we refer to a device operating in that manner as a deeply depleted graphene-oxide-semiconductor (D2GOS) detector. |
| FILED | Wednesday, October 17, 2018 |
| APPL NO | 16/162756 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/17 (20130101) Original (OR) Class G01T 1/185 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14659 (20130101) H01L 29/1606 (20130101) H01L 31/028 (20130101) H01L 31/119 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11288095 | Dutu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Alexandru Dutu (Bellevue, Washington); Matthew D. Sinclair (Bellevue, Washington); Bradford M. Beckmann (Bellevue, Washington); David A. Wood (Austin, Texas) |
| ABSTRACT | A technique for synchronizing workgroups is provided. The techniques comprise detecting that one or more non-executing workgroups are ready to execute, placing the one or more non-executing workgroups into one or more ready queues based on the synchronization status of the one or more workgroups, detecting that computing resources are available for execution of one or more ready workgroups, and scheduling for execution one or more ready workgroups from the one or more ready queues in an order that is based on the relative priority of the ready queues. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/588872 |
| ART UNIT | 2196 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/52 (20130101) G06F 9/4881 (20130101) Original (OR) Class G06F 2209/521 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11288194 | Johns et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles R. Johns (Austin, Texas); James A. Kahle (Austin, Texas); Martin Ohmacht (Yorktown Heights, New York); Changhoan Kim (Westchester, New York); Jose R. Brunheroto (Mohegan Lake, New York); Constantinos Evangelinos (Cambridge, Massachusetts); Abdullah Kayi (Westchester, New York); Alessandro Morari (New York, New York); James C. Sexton (Yorktown Heights, New York); Patrick D. Siegl (White Plains, New York) |
| ABSTRACT | An approach is disclosed that maintains a consistent view of a virtual address by a local node which writes a first value to the virtual address and, after writing the first value, establishes a snapshot consistency state of the virtual address. The virtual address is shared amongst any number of processes and the processes includes a writing process and other processes that read from the virtual address. After writing the first value, the writing process writes a second value to the virtual address. Even after writing the second value, the first value is still visible to the other processes. |
| FILED | Wednesday, December 12, 2018 |
| APPL NO | 16/217257 |
| ART UNIT | 2184 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0815 (20130101) Original (OR) Class G06F 2212/657 (20130101) G06F 2212/1008 (20130101) G06F 2212/1048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11288208 | Nair et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Ravi Nair (Briarcliff Manor, New York); Charles R. Johns (Austin, Texas); James A. Kahle (Austin, Texas); Changhoan Kim (Westchester, New York); Constantinos Evangelinos (Cambridge, Massachusetts); Patrick D. Siegl (White Plains, New York) |
| ABSTRACT | An approach is described that provides access to a named data element in a Coordination Namespace that is stored in a memory that is distributed amongst a set of nodes. A request of a name corresponding to the named data element is received from a requesting process and the approach responsively searches for the name in the Coordination Namespace. In response to determining an absence of data corresponding to the named data element, a pending state is indicated to the requesting process. In response to determining that the data corresponding to the named data element exists, a successful state is returned to the requesting process. In one embodiment, the successful state also includes providing the requesting process with access to the data corresponding to the named data element. |
| FILED | Wednesday, December 12, 2018 |
| APPL NO | 16/218118 |
| ART UNIT | 2139 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 9/544 (20130101) G06F 9/546 (20130101) G06F 12/0284 (20130101) G06F 12/0692 (20130101) G06F 12/0824 (20130101) G06F 12/1018 (20130101) G06F 12/1072 (20130101) Original (OR) Class G06F 13/1663 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11288424 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan); UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan); UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Jian Chen (Oak Ridge, Tennessee); Hui Huang (Oak Ridge, Tennessee); Zhili Feng (Oak Ridge, Tennessee); Blair Carlson (Ann Arbor, Michigan); Hui-Ping Wang (Warren, Michigan); Wayne Cai (Troy, Michigan) |
| ABSTRACT | A method for accelerating an explicit finite element analysis (FEA) simulation of a modeled system or process includes performing an initial iteration of the FEA simulation according to a baseline time interval via an FEA computing network, and calculating a criteria ratio of a predetermined set of scaling criteria for the modeled system or process. The method includes determining a time-scaling factor using the criteria ratio via the FEA computing network as a function of the criteria ratio, and then applying the time-scaling factor to the baseline time interval to generate a scaled time interval. The scaled time interval accelerates simulation time of the FEA simulation. The method includes performing a subsequent iteration of the explicit FEA simulation at the scaled time interval using the FEA computing network. The process continues for subsequent iterations, with the time-scaling factor adapting with each iteration. |
| FILED | Tuesday, June 25, 2019 |
| APPL NO | 16/451513 |
| ART UNIT | 2146 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 17/11 (20130101) G06F 30/23 (20200101) Original (OR) Class Image Data Processing or Generation, in General G06T 15/005 (20130101) G06T 19/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11288434 | Trujillo |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Joshua Trujillo (Albuquerque, New Mexico) |
| ABSTRACT | A computer-implemented method of generating randomized electrical interconnects for an electronic circuit comprises steps of receiving a netlist of nodes of electronic components to be connected, each connection between the nodes forming an electrical interconnect; determining a list of one or more path directions for each electrical interconnect; determining a plurality of path direction distances for each electrical interconnect; generating a plurality of segments for each electrical interconnect, each segment having one path direction and a length which are selected at random; calculating a sum of the lengths of all segments of the plurality of segments in each path direction each time a segment is generated for each electrical interconnect; removing one path direction from the list of path directions when a first condition is met; and stopping the generating a plurality of segments for each electrical interconnect when a second condition is met. |
| FILED | Friday, September 04, 2020 |
| APPL NO | 17/012234 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Electric Digital Data Processing G06F 30/392 (20200101) Original (OR) Class G06F 30/394 (20200101) G06F 30/398 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11289156 | Frank et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Michael P. Frank (Albuquerque, New Mexico); Erik Debenedictis (Albuquerque, New Mexico) |
| ABSTRACT | A reversible memory element is provided. The reversible memory element comprises a reversible memory cell comprising a Josephson junction and a passive inductor. A ballistic interconnect is connected to the reversible memory cell by a bidirectional input/output port. A polarized input fluxon propagating along the ballistic interconnect exchanges polarity with a stationary stored fluxon in the reversible memory cell in response to the input fluxon reflecting off the reversible memory cell. |
| FILED | Thursday, July 30, 2020 |
| APPL NO | 16/943613 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/0354 (20130101) Static Stores G11C 11/44 (20130101) Original (OR) Class G11C 11/1673 (20130101) G11C 11/1675 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/025 (20130101) H01L 39/223 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11289213 | Lahoda et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WESTINGHOUSE ELECTRIC COMPANY LLC (Cranberry Township, Pennsylvania) |
| ASSIGNEE(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| INVENTOR(S) | Edward J. Lahoda (Edgewood, Pennsylvania); Frank A. Boylan (Ellwood City, Pennsylvania); Ho Q. Lam (Verona, Pennsylvania); Mitchell E. Nissley (Trafford, Pennsylvania); Raymond E. Schneider (South Windsor, Connecticut); Robert L. Oelrich (Columbia, South Carolina); Sumit Ray (Columbia, South Carolina); Radu Pomirleanu (Wexford, Pennsylvania); Zeses Karoutas (Lexington, South Carolina); Michael J. Hone (Prospect, Pennsylvania) |
| ABSTRACT | A control rod for a nuclear fuel assembly is described herein that includes a neutron absorbing material having a melting point greater than 1500° C. that does not form a eutectic with a melting point less than 1500° C., and may further include a cladding material having a melting point greater than 1500° C. The cladding material is selected from the group consisting of silicon carbide, zirconium, a zirconium alloy, tungsten, and molybdenum. The absorbing material is selected from the group consisting of Gd2O3, Ir, B4C, Re, and Hf. The metal cladding or the absorbing material may be coated with an anti-oxidation coating of Cr with or without a Nb intermediate layer. |
| FILED | Wednesday, August 01, 2018 |
| APPL NO | 16/051712 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 30/00 (20130101) Nuclear Reactors G21C 1/08 (20130101) G21C 3/07 (20130101) G21C 3/328 (20130101) G21C 7/10 (20130101) G21C 7/24 (20130101) Original (OR) Class G21C 11/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11289231 | Larsen, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| INVENTOR(S) | George K. Larsen, III (Aiken, South Carolina); Simona E. Hunyadi Murph (North Augusta, South Carolina) |
| ABSTRACT | Radiation detectors and methods of using the radiation detectors that provide a route for surface decontamination during use are described. The detectors utilize light illumination of an internal surface during use. Light is in the longer UV-to-near-infrared spectra and desorbs contamination from internal surfaces of radiation detectors. The methods can be carried out while the detectors are in operation, preventing the appearance of the negative effects of radioactive and non-radioactive contamination during a detection regime and following a detection regime. |
| FILED | Thursday, August 27, 2020 |
| APPL NO | 17/004646 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Cleaning in General; Prevention of Fouling in General B08B 7/0057 (20130101) Measurement of Nuclear or X-radiation G01T 1/185 (20130101) G01T 7/00 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 9/002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11289248 | Pathak et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Arjun K. Pathak (Ames, Iowa); Yaroslav Mudryk (Ames, Iowa); Oleksandr Dolotko (Ames, Iowa); Vitalij K. Pecharsky (Ames, Iowa) |
| ABSTRACT | A magnetocaloric material comprising a La—Fe—Si based alloy composition that is compositionally modified to include a small but effective amount of at least one of Al, Ga, and In to improve mechanical stability of the alloy (substantially reduce alloy brittleness), improve thermal conductivity, and preserve comparable or provide improved magnetocaloric effects. The alloy composition may be further modified by inclusion of at least one of Co, Mn, Cr, and V as well as interstitial hydrogen. |
| FILED | Monday, February 11, 2019 |
| APPL NO | 16/501027 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/00 (20141201) Alloys C22C 33/04 (20130101) C22C 38/02 (20130101) C22C 38/005 (20130101) C22C 38/06 (20130101) C22C 2202/02 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/015 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11289640 | Solovyov |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brookhaven Technology Group, Inc. (Stony Brook, New York) |
| ASSIGNEE(S) | Brookhaven Technology Group, Inc. (Stony Brook, New York) |
| INVENTOR(S) | Vyacheslav Solovyov (Rocky Point, New York) |
| ABSTRACT | A high-temperature superconducting filament and cable, and a method for manufacturing same. The substrate used to grow the superconducting layer is removed, and the exfoliated superconducting layer is coated with a protective layer, and then sliced into narrow strips. The strips are thereafter encapsulated with a conductive metal to provide a high-temperature superconducting filament. The filaments may be bundled together to provide a high-temperature superconducting cable. |
| FILED | Friday, January 20, 2017 |
| APPL NO | 16/071772 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 12/06 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/143 (20130101) H01L 39/248 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11289689 | Du et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UTBATTELE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Zhijia Du (Knoxville, Tennessee); Christopher James Janke (Oliver Springs, Tennessee); Jianlin Li (Knoxville, Tennessee); David L. Wood, III (Knoxville, Tennessee); Claus Daniel (Knoxville, Tennessee) |
| ABSTRACT | A method of making an electrode includes the step of mixing active material particles, radiation curable resin precursors, and electrically conductive particles to create an electrode precursor mixture. The electrode precursor mixture is electrostatically sprayed onto a current collector to provide an electrode preform. The electrode preform is heated and calendered to melt the resin precursor such that the resin precursor surrounds the active particles and electrically conductive particles. Radiation is applied to the electrode preform sufficient to cure the radiation curable resin precursors into resin. |
| FILED | Monday, April 30, 2018 |
| APPL NO | 15/966840 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0404 (20130101) H01M 4/0419 (20130101) Original (OR) Class H01M 4/0435 (20130101) H01M 4/0471 (20130101) H01M 4/621 (20130101) H01M 4/1315 (20130101) H01M 4/1391 (20130101) H01M 4/1393 (20130101) H01M 4/1397 (20130101) H01M 4/13915 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11289700 | Whittingham et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| INVENTOR(S) | M. Stanley Whittingham (Vestal, New York); Jia Ding (Binghamton, New York) |
| ABSTRACT | An electrode comprising: NaVOPO4 having orthorhombic crystalline symmetry and space group Pna21, as an active intercalation host material, wherein the electrode is capable of electrochemical insertion and release of greater than one sodium ion per vanadium, wherein the NaVOPO4 is formed by a solid phase synthesis process from a heated powdered mixture of ammonium metavanadate, ammonium phosphate monobasic, and potassium carbonate, to yield KVOPO4 having corner-sharing VO6 octahedra and PO4 tetrahedra, defining two types of tunnels comprising a first type of tunnel formed of rings of two PO4 tetrahedra and a second type of tunnel formed of rings of three PO4 tetrahedra and three VO6 octahedra, followed by substitution of the potassium ions with sodium ions. |
| FILED | Monday, June 26, 2017 |
| APPL NO | 15/633240 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 31/006 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 14/18 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/01 (20180101) C08K 3/04 (20130101) C08K 3/32 (20130101) C08K 2003/328 (20130101) Compositions of Macromolecular Compounds C08L 9/08 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 127/16 (20130101) C09D 127/16 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/381 (20130101) Original (OR) Class H01M 4/622 (20130101) H01M 4/623 (20130101) H01M 4/625 (20130101) H01M 4/5825 (20130101) H01M 10/054 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11289701 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Amprius, Inc. (Fremont, California) |
| ASSIGNEE(S) | Amprius, Inc. (Fremont, California) |
| INVENTOR(S) | Weijie Wang (Sunnyvale, California); Zuqin Liu (Sunnyvale, California); Song Han (Foster City, California); Jonathan Bornstein (Cupertino, California); Constantin Ionel Stefan (San Jose, California) |
| ABSTRACT | Provided herein are nanostructures for lithium ion battery electrodes and methods of fabrication. In some embodiments, a nanostructure template coated with a silicon coating is provided. The silicon coating may include a non-conformal, more porous layer and a conformal, denser layer on the non-conformal, more porous layer. In some embodiments, two different deposition processes, e.g., a PECVD layer to deposit the non-conformal layer and a thermal CVD process to deposit the conformal layer, are used. Anodes including the nanostructures have longer cycle lifetimes than anodes made using either a PECVD or thermal CVD method alone. |
| FILED | Wednesday, May 13, 2020 |
| APPL NO | 15/931470 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/134 (20130101) H01M 4/366 (20130101) H01M 4/386 (20130101) Original (OR) Class H01M 4/0428 (20130101) H01M 4/1395 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11289876 | Jayaraman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Thorlabs, Inc. (Newton, New Jersey); Praevium Research, Inc. (Santa Barbara, California) |
| ASSIGNEE(S) | Thorlabs, Inc. (Newton, New Jersey); Praevium Research, Inc. (Santa Barbara, California) |
| INVENTOR(S) | Vijaysekhar Jayaraman (Goleta, California); Kevin Lascola (Columbia, Maryland); Stephen Segal (Columbia, Maryland); Fredrick Towner (Fulton, Maryland); Alex Cable (Newton, New Jersey) |
| ABSTRACT | Disclosed is an optically pumped vertical cavity laser structure operating in the mid-infrared region, which has demonstrated room-temperature continuous wave operation. This structure uses a periodic gain active region with type I quantum wells comprised of InGaAsSb, and barrier/cladding regions which provide strong hole confinement and substantial pump absorption. A preferred embodiment includes at least one wafer bonded GaAs-based mirror. Several preferred embodiments also include means for wavelength tuning of mid-IR VCLs as disclosed, including a MEMS-tuning element. This document also includes systems for optical spectroscopy using the VCL as disclosed, including systems for detection concentrations of industrial and environmentally important gases. |
| FILED | Thursday, July 09, 2020 |
| APPL NO | 16/924969 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) G01J 2003/423 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/041 (20130101) Original (OR) Class H01S 5/1838 (20130101) H01S 5/3218 (20130101) H01S 5/3403 (20130101) H01S 5/18358 (20130101) H01S 5/18361 (20130101) H01S 5/18366 (20130101) H01S 5/18377 (20130101) H01S 5/18383 (20130101) H01S 5/34306 (20130101) H01S 5/34366 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11290023 | Blasko |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Vladimir Blasko (Avon, Connecticut) |
| ABSTRACT | A matrix converter system operating in current control mode is provided. The matrix converter includes a switching matrix coupled between a low voltage side and a high voltage side, wherein the matrix converter is coupled at its low voltage side to a generator for receiving an input power including an input current and transforming the input power into an output power at its high voltage side, wherein a load is coupled to the high voltage side. The control system includes a load observer and a model predictive controller (MPC). The load observer is configured to estimate a load current that flows to the load from the high voltage side of the matrix converter as a function of a switching state of the switching matrix, an output voltage output at the high voltage side of the matrix converter, and the input current. The MPC is configured to select the switching state of the switching matrix to meet one or more control objectives defined by minimization of a multi-objective function that tracks the output voltage and the input current using the estimated load current. |
| FILED | Thursday, April 11, 2019 |
| APPL NO | 16/381947 |
| ART UNIT | 2839 — Semiconductors/Memory |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/048 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 5/2576 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11290088 | Nojima |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Eaton Intelligent Power Limited (Dublin, Ireland) |
| ASSIGNEE(S) | Eaton Intelligent Power Limited (, None) |
| INVENTOR(S) | Geraldo Nojima (Fort Mill, South Carolina) |
| ABSTRACT | An apparatus includes a plurality of parallel-connected semiconductor switches (e.g., silicon carbide (SiC) metal oxide semiconductor field effect transistors (MOSFETs) or other wide-bandgap semiconductor switches) and a plurality of driver circuits having outputs configured to be coupled to control terminals of respective ones of the plurality of semiconductor switches and configured to drive the parallel-connected semiconductor switches responsive to a common switch state control signal. The driver circuits may have respective different power supplies, which may be adjustable. Respective output resistors may couple respective ones of the driver circuits to respective ones of the semiconductor switches. The output resistors may be adjustable. |
| FILED | Wednesday, February 19, 2020 |
| APPL NO | 16/795261 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Pulse Technique H03K 3/011 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11291020 | Moradi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hussein Moradi (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hussein Moradi (Idaho Falls, Idaho); Behrouz Farhang (Salt Lake City, Utah) |
| ABSTRACT | Apparatuses, systems and methods are disclosed for wireless communication. A base station may communicate with a plurality of user equipments (UEs) without allocating spectral resources to the UEs for communicating scheduling requests. The base station may detect a scheduling request from a requesting UE of the plurality of UEs. The scheduling request may include a spread spectrum signal based on a spreading sequence. The scheduling request may indicate an identity for a requesting UE without indicating information other than the identity. The base station may grant spectral resources to the requesting UE in response to detecting a scheduling request. |
| FILED | Friday, April 10, 2020 |
| APPL NO | 16/846239 |
| ART UNIT | 2464 — Multiplex and VoIP |
| CURRENT CPC | Transmission H04B 1/69 (20130101) Wireless Communication Networks H04W 72/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11291101 | Timpson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Erik Joseph Timpson (Olathe, Kansas); Joseph Ambrose Wolf (Olathe, Kansas) |
| ABSTRACT | A system for creating a plasma field Faraday cage around a structure, the system comprising a plurality of lasers spaced apart from each other, each laser being configured to transmit an electromagnetic energy beam to a focal point of an atmosphere region, each electromagnetic energy beam having an amount of energy less than an amount of energy required to ionize air, the electromagnetic energy beams intersecting at the focal point such that the electromagnetic energy beams cooperatively ionize the air at the focal point to block electromagnetic radiation from passing through the focal point. |
| FILED | Monday, August 24, 2020 |
| APPL NO | 17/001112 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | X-ray Technique H05G 2/008 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11291104 | Kroc |
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| FUNDED BY |
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| APPLICANT(S) | FERMI RESEARCH ALLIANCE, LLC (Batavia, Illinois) |
| ASSIGNEE(S) | FERMI RESEARCH ALLIANCE, LLC (Batavia, Illinois) |
| INVENTOR(S) | Thomas Kroc (Batavia, Illinois) |
| ABSTRACT | A magnetic apparatus and a method of operating the magnetic apparatus can include a scanning electromagnet that redirects a beam of charged particles, a vacuum chamber that prevents the atmosphere from interfering with the charged particles, and, a parallelizing permanent magnet array for parallelizing the beam of charged particles. The parallelizing permanent magnet array can be located proximate to a target comprising a Bremsstrahlung target or an object that is being irradiated. The magnetic field of the scanning electromagnet can be variable to produce all angles necessary to sweep the beam of charged particles across the target and the parallelizing permanent magnet array can be configured from a magnetic material that does not require an electric current. |
| FILED | Wednesday, December 09, 2020 |
| APPL NO | 17/116880 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/04 (20130101) Original (OR) Class H05H 2007/046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11285607 | Rus et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Daniela Rus (Weston, Massachusetts); Jeffrey Lipton (Medford, Massachusetts); Aidan Fay (La Jolla, California); Changhyun Choi (Minneapolis, Minnesota) |
| ABSTRACT | In some aspects, a system comprises a computer hardware processor and a non-transitory computer-readable storage medium storing processor-executable instructions for receiving, from one or more sensors, sensor data relating to a robot; generating, using a statistical model, based on the sensor data, first control information for the robot to accomplish a task; transmitting, to the robot, the first control information for execution of the task; and receiving, from the robot, a result of execution of the task. |
| FILED | Monday, July 15, 2019 |
| APPL NO | 16/511492 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/163 (20130101) B25J 9/1689 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286451 | Morgan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| ASSIGNEE(S) | Brown University (Providence, Rhode Island) |
| INVENTOR(S) | Jeffrey R. Morgan (Sharon, Massachusetts); Kali L. Manning (Pawtucket, Rhode Island); Blanche Ip (Providence, Rhode Island) |
| ABSTRACT | The invention provides a device and a method for the assembly of an aggregation of adherent cells, particularly a three-dimensional assembly of adherent cells. |
| FILED | Tuesday, February 05, 2019 |
| APPL NO | 16/967182 |
| ART UNIT | 1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 2513/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286491 | Joshi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Neel Satish Joshi (Somerville, Massachusetts); Peter Q. Nguyen (Malden, Massachusetts); Anna M. Duraj-Thatte (Arlington, Massachusetts); Pichet Praveschotinunt (Cambridge, Massachusetts) |
| ABSTRACT | Methods of making biofilms having non-native functional polypeptides attached thereto are provided. |
| FILED | Monday, February 10, 2020 |
| APPL NO | 16/785874 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) Peptides C07K 14/33 (20130101) C07K 14/245 (20130101) C07K 2317/24 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) Original (OR) Class C12N 15/70 (20130101) C12N 2800/101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286517 | Kishi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Jocelyn Yoshiko Kishi (Boston, Massachusetts); Thomas E. Schaus (Arlington, Massachusetts); Peng Yin (Brookline, Massachusetts); Feng Xuan (Boston, Massachusetts); Nikhil Gopalkrishnan (Jamaica Plain, Massachusetts); Sungwook Woo (Chestnut Hill, Massachusetts) |
| ABSTRACT | The present disclosure provides, in some aspects, nucleic acid-based molecular tools that enable the recording of molecular structure and soluble signals as well as the programmed assembly of molecular structures. |
| FILED | Thursday, February 16, 2017 |
| APPL NO | 15/999245 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/64 (20130101) C12N 15/113 (20130101) C12N 2310/122 (20130101) C12N 2310/127 (20130101) C12N 2330/50 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6809 (20130101) C12Q 1/6811 (20130101) Original (OR) Class C12Q 1/6825 (20130101) C12Q 1/6825 (20130101) C12Q 1/6853 (20130101) C12Q 1/6853 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2525/186 (20130101) C12Q 2525/186 (20130101) C12Q 2525/204 (20130101) C12Q 2525/204 (20130101) C12Q 2525/301 (20130101) C12Q 2525/301 (20130101) C12Q 2525/301 (20130101) C12Q 2531/101 (20130101) C12Q 2531/101 (20130101) C12Q 2531/119 (20130101) C12Q 2531/119 (20130101) C12Q 2531/119 (20130101) C12Q 2533/101 (20130101) C12Q 2533/101 (20130101) C12Q 2537/16 (20130101) C12Q 2537/16 (20130101) C12Q 2537/149 (20130101) C12Q 2537/149 (20130101) C12Q 2537/157 (20130101) C12Q 2537/157 (20130101) C12Q 2537/163 (20130101) C12Q 2537/163 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1376 (20130101) C12Q 2537/1376 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286549 | Monroe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James Alan Monroe (Syracuse, New York); Jeremy Sean McAllister (New York, New York); Jay Russell Zgarba (Sugar Land, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James Alan Monroe (Syracuse, New York); Jeremy Sean McAllister (New York, New York); Jay Russell Zgarba (Sugar Land, Texas) |
| ABSTRACT | Systems and methods disclosed herein relate to the manufacture of metallic material with a thermal expansion coefficient in a predetermined range, comprising: deforming, a metallic material comprising a first phase and a first thermal expansion coefficient. In response to the deformation, at least some of the first phase is transformed into a second phase, wherein the second phase comprises martensite, and orienting the metallic material in at least one predetermined orientation, wherein the metallic material, subsequent to deformation, comprises a second thermal expansion coefficient, wherein the second thermal expansion coefficient is within a predetermined range, and wherein the thermal expansion is in at least one predetermined direction. In some embodiments, the metallic material comprises the second phase and is thermo-mechanically deformed to orient the grains in at least one direction. |
| FILED | Monday, February 03, 2020 |
| APPL NO | 16/780830 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Alloys C22C 5/00 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286551 | Rajagopalan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Jagannathan Rajagopalan (Tempe, Arizona); Rohit Berlia (Tempe, Arizona) |
| ABSTRACT | In a method of forming a metallic material with a multimodal microstructure, nickel is deposited on a substrate having a patterned surface comprising two materials having differing microstructure. The resulting materials may desirably be utilized in semiconductor devices or microelectromechanical (MEMS) devices. |
| FILED | Monday, October 12, 2020 |
| APPL NO | 17/068500 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/025 (20130101) Original (OR) Class C23C 14/085 (20130101) C23C 30/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287627 | Preza et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Chrysanthe Preza (Memphis, Tennessee); Ana Doblas (Memphis, Tennessee); Genaro Saavedra-Tortosa (Valencia, Spain); Manuel Martinez-Corral (Valencia, Spain); Juan Carlos Barreiro (Valencia, Spain) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chrysanthe Preza (Memphis, Tennessee); Ana Doblas (Memphis, Tennessee); Genaro Saavedra-Tortosa (Valencia, Spain); Manuel Martinez-Corral (Valencia, Spain); Juan Carlos Barreiro (Valencia, Spain) |
| ABSTRACT | A multi-focal light-sheet structured illumination system that can be implemented as a part of a commercial fluorescence microscope or a module that is adaptable to fit a number of commercially available microscopes. The system provides simultaneous capture of 2D images from multiple planes within a 3D volume, which are resolved laterally and axially to provide improved resolution along the three dimensions (x,y,z). A Wollaston prism allows several axially-localized high-contrast structure illumination patterns to be generated. |
| FILED | Saturday, June 30, 2018 |
| APPL NO | 16/024807 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/0032 (20130101) G02B 21/0064 (20130101) G02B 21/0076 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287633 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Jonathan T. C. Liu (Seattle, Washington); Lindsey A. Barner (Seattle, Washington); Adam K. Glaser (Seattle, Washington) |
| ABSTRACT | Apparatuses, systems, and methods for solid immersion meniscus lenses (SIMlenses). An optical system may include a sample holder with a first side which supports a sample, and a second side opposite the first side. The second side of the sample holder may be in contact with an immersion fluid. Light passing between the sample and an objective lens may pass through the sample holder, immersion fluid, and a SIMlens positioned between the immersion fluid and objective. The SIMlens may have a first curved surface and a second curved surface, each of which may be shaped to match a wavefront of the light as it passes through the SIMlens. The immersion fluid, SIMlens, and environment containing the objective may all have different refractive indices. |
| FILED | Wednesday, June 23, 2021 |
| APPL NO | 17/356135 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/26 (20130101) G02B 21/0032 (20130101) G02B 21/33 (20130101) Original (OR) Class G02B 21/248 (20130101) G02B 21/367 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287642 | Valentine et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Jason G. Valentine (Nashville, Tennessee); Cary L. Pint (Nashville, Tennessee); Zachary J. Coppens (Nashville, Tennessee); Adam P. Cohn (Nashville, Tennessee) |
| ABSTRACT | A device according to one example of principles described herein may include a backplane, electrochemical actuator, and an optical resonator, wherein the electrochemical actuator is located between the backplane and optical resonator. Applied energy may be used to modify the volume of the electrochemical actuator material modifying the resonant/interferometric absorption, transmission, and reflection at visible and/or infrared frequencies. |
| FILED | Wednesday, September 19, 2018 |
| APPL NO | 16/135697 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 26/001 (20130101) Original (OR) Class G02B 26/085 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/21 (20130101) G02F 1/0123 (20130101) G02F 1/155 (20130101) G02F 1/213 (20210101) G02F 2001/1536 (20130101) G02F 2201/083 (20130101) G02F 2203/02 (20130101) G02F 2203/15 (20130101) G02F 2203/055 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287971 | Welch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Gregory Welch (Orlando, Florida); Ryan McMahan (Orlando, Florida); Gerd Bruder (Orlando, Florida) |
| ABSTRACT | A system for remote tactile telepresence wherein tactile telepresence sessions are time-coded along with audiovisual content wherein playback is heard, seen, and felt. Embodiments associate motion capture with the tactile profile so that remote, haptic recipients may see renderings of objects (e.g., hands) imparting vibrotactile sensations. |
| FILED | Wednesday, July 28, 2021 |
| APPL NO | 17/387219 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 3/014 (20130101) G06F 3/016 (20130101) G06F 3/04842 (20130101) G06F 3/04883 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11288261 | Gupta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Amarnath Gupta (San Diego, California); Subhasis Dasgupta (San Diego, California); Margaret Roberts (San Diego, California) |
| ABSTRACT | A method may include determining, based on a data analysis plan that includes analytical operations performed on at least a portion of the dataset being ingested into and/or stored in the polystore, an optimization for the ingestion of the dataset into the polystore. The ingestion of the dataset includes storing, in a first database management system and/or a second database management system in the polystore, the portion of the dataset. The analysis plan may be modified, based on the optimization, by adding, removing, and/or reordering one or more analytical operations included in the data analysis plan. During the ingestion of the dataset, the optimization may be applied by routing, based on the optimization, the portion of the dataset for storage at the first database management system and/or the second database management system. Related systems and articles of manufacture are also provided. |
| FILED | Tuesday, December 04, 2018 |
| APPL NO | 16/209397 |
| ART UNIT | 2165 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/2379 (20190101) Original (OR) Class G06F 16/24542 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11288379 | Mireshghallah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Fatemehsadat Mireshghallah (La Jolla, California); Hadi Esmaeilzadeh (La Jolla, California) |
| ABSTRACT | Methods and systems that provide data privacy for implementing a neural network-based inference are described. A method includes injecting stochasticity into the data to produce perturbed data, wherein the injected stochasticity satisfies an ε-differential privacy criterion and transmitting the perturbed data to a neural network or to a partition of the neural network for inference. |
| FILED | Thursday, August 26, 2021 |
| APPL NO | 17/458165 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 21/60 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6228 (20130101) G06K 9/6298 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11288412 | Golparvar-Fard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Mani Golparvar-Fard (Champaign, Illinois); Derek Hoiem (Champaign, Illinois); Jacob Je-Chian Lin (Urbana, Illinois); Kook In Han (Cary, North Carolina); Joseph M. Degol (Urbana, Illinois) |
| ABSTRACT | A system initializes a set of calibrated images with known 3D pose relative to a 3D building information model (BIM) to be anchor images, detects features within images of unknown position and orientation, and determines matches with features of the calibrated images. The system determines a subset of the images that have at least a threshold number of matching features, selects an image from the subset of the images having the largest number of matching features, and executes a reconstruction algorithm using the image and the anchor images to calibrate the image to the BIM and generate an initial 3D point cloud model. The system repeats the last steps to identify a second image from the subset and perform, starting with the initial 3D point cloud model and using the second image, 3D reconstruction to generate an updated 3D point cloud model that is displayable in a graphical user interface. |
| FILED | Wednesday, April 18, 2018 |
| APPL NO | 15/956266 |
| ART UNIT | 2148 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 3/04815 (20130101) G06F 30/13 (20200101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0633 (20130101) G06Q 10/0635 (20130101) G06Q 10/06313 (20130101) G06Q 10/06316 (20130101) G06Q 10/06393 (20130101) G06Q 50/08 (20130101) Image Data Processing or Generation, in General G06T 15/20 (20130101) G06T 17/05 (20130101) G06T 19/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11288815 | Qiu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Peng Qiu (Atlanta, Georgia); Todd Sulchek (Atlanta, Georgia) |
| ABSTRACT | A system for tracking single-cell movement trajectories is disclosed. The system can record, to a plurality of frames, cells (events) within a microfluidic device. Also, the system can identify an event within each frame including whether the event is a single cell or multiple cells. When the event appears differently between frames (e.g., single cell in one frame and multiple cells in another frame), the system can either segment or merge the cell(s). Then, the system can determine a trajectory for the events based on a position of the event in the frames. Further, the system can determine cell properties based on the trajectory of the events. |
| FILED | Monday, January 06, 2020 |
| APPL NO | 16/734749 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00134 (20130101) G06K 9/00711 (20130101) G06K 2009/00738 (20130101) Image Data Processing or Generation, in General G06T 7/20 (20130101) Original (OR) Class G06T 2207/30241 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11288818 | Daniilidis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Konstantinos Daniilidis (Wynnewood, Pennsylvania); Alex Zihao Zhu (Philadelphia, Pennsylvania) |
| ABSTRACT | A method for prediction of an indication of motion using input from an event-based camera includes receiving events captured by an event-based camera, wherein each of the events represents a location of a change in pixel intensity, a polarity of the change, and a time. The method further includes discretizing the events into time discretized event volumes, each of which contain events that occur within a specified time range. The method further includes providing the time discretized event volumes as input to an encoder-decoder neural network trained to predict an indication of motion using a loss function that measures quality of image deblurring; generating, using the neural network, a prediction of the indication of motion. The method further includes using the prediction of the indication of motion in a machine vision application. |
| FILED | Wednesday, February 19, 2020 |
| APPL NO | 16/795079 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/0472 (20130101) Image Data Processing or Generation, in General G06T 7/246 (20170101) Original (OR) Class G06T 2207/20084 (20130101) G06T 2207/30252 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11289299 | Williams |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Peter Williams (Phoenix, Arizona) |
| ABSTRACT | A duoplasmatron ion source with a partially ferromagnetic anode can be used in multiple applications, including the production of negative ions for secondary ion mass spectrometers and particle accelerators. A partially ferromagnetic anode, which may be embodied in a partially ferromagnetic anode insert, includes a ferromagnetic and non-ferromagnetic portions joined together at a juncture, with an ion extraction aperture defined in the ferromagnetic portion and the juncture being laterally offset from the aperture. An asymmetric magnetic field produced by the partially ferromagnetic region facilitates extraction of charged ions from the central, most intense region of a source plasma in the duoplasmatron ion source. A ferromagnetic conical portion of the anode defines the ion extraction aperture in order to maximize the magnetic field in the vicinity of this aperture. |
| FILED | Friday, October 23, 2020 |
| APPL NO | 16/972384 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 9/14 (20130101) H01J 27/10 (20130101) Original (OR) Class H01J 49/123 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11289321 | Cooks et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Robert Graham Cooks (West Lafayette, Indiana); Jason Duncan (Dayton, Indiana); Joshua Wiley (Lafayette, Indiana) |
| ABSTRACT | The invention generally relates to ion traps and methods of use thereof. In certain embodiments, the invention provides a system that includes a mass spectrometer including an ion trap, and a central processing unit (CPU). The CPU has storage that is coupled to the CPU for storing instructions that when executed by the CPU cause the system to apply a constant radio frequency (RF) signal to the ion trap, and apply a first alternating current (AC) signal to the ion trap the frequency of which varies as a function of time. |
| FILED | Wednesday, October 14, 2020 |
| APPL NO | 17/070411 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/0031 (20130101) H01J 49/422 (20130101) H01J 49/426 (20130101) Original (OR) Class H01J 49/427 (20130101) H01J 49/4285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11289386 | Basol et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Active Layer Parametrics, Inc. (Scotts Valley, California) |
| ASSIGNEE(S) | Active Layer Parametrics, Inc. (Scotts Valley, California) |
| INVENTOR(S) | Bulent Mehmet Basol (Manhattan Beach, California); Jalal Ashjaee (Cupertino, California); Abhijeet Joshi (San Jose, California) |
| ABSTRACT | A method for electrically characterizing a layer disposed on a substrate and electrically insulated from the substrate is disclosed. The method can include forming a test pattern, contacting the test pattern with electrical contact elements at contact regions, and measuring an electrical parameter of the layer by passing a first set of test currents between contact regions. The test pattern can be formed by pushing a pattern forming head against a top surface of the layer, introducing a first fluid into the cavity, and converting the sacrificial portion of the layer into an insulator using the first fluid and forming the test pattern under the test-pattern-shaped inner seal. |
| FILED | Monday, March 16, 2020 |
| APPL NO | 16/820447 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/2644 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/326 (20130101) H01L 21/02318 (20130101) H01L 21/6715 (20130101) H01L 22/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11289729 | Nuckolls et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Colin Nuckolls (New York, New York); Raul Hernandez Sanchez (New York, New York); Yuan Yang (New York, New York); Thomas Sisto (New York, New York); Margarita Milton (New York, New York) |
| ABSTRACT | The present disclosure relates to organic electrolyte solutions including organic electrolytes (e.g., aromatic imides, ferrocenes, spiro fused compounds, or cyclopropenium compounds), and redox flow batteries and systems including the same. |
| FILED | Monday, February 17, 2020 |
| APPL NO | 16/792501 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/20 (20130101) Original (OR) Class H01M 8/2435 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11289879 | Yun |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Seok Hyun Yun (Belmont, Massachusetts) |
| ABSTRACT | Disclosed are photonic particles and methods of using particles in biological samples. The particles are configured to emit laser light when energetically stimulated by, e.g., a pump source. The particles may include a gain medium with inorganic materials, an optical cavity with high refractive index, and a coating with organic materials. The particles may be smaller than 3 microns along their longest axes. The particles may attach to each other to form, e.g., doublets and triplets. The particles may be injection-locked by coupling an injection beam into a particle while pumping so that an injection seed is amplified to develop into laser oscillation. A microscopy system may include a pump source, beam scanner, spectrometer with resolution of less than 1 nanometer and acquisition rate of more than 1 kilohertz, and spectral analyzer configured to distinguish spectral peaks of laser output from broadband background. |
| FILED | Monday, June 08, 2020 |
| APPL NO | 16/895914 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 2003/2826 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/648 (20130101) G01N 2015/1006 (20130101) G01N 2021/6439 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/091 (20130101) H01S 3/169 (20130101) H01S 3/213 (20130101) H01S 3/0604 (20130101) H01S 5/36 (20130101) H01S 5/40 (20130101) H01S 5/041 (20130101) H01S 5/1025 (20130101) H01S 5/1067 (20130101) Original (OR) Class H01S 5/1075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11285154 | Habib |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as Represented by The Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Amyn Aziz Habib (Dallas, Texas) |
| ABSTRACT | Provided herein are methods and pharmaceutical compositions for treating cancer, in a patient in need thereof, said method comprising administering to said patient an effective amount of an EGFR inhibitor and a TNF inhibitor. |
| FILED | Thursday, March 29, 2018 |
| APPL NO | 15/940802 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/17 (20130101) A61K 31/277 (20130101) A61K 31/277 (20130101) A61K 31/416 (20130101) A61K 31/416 (20130101) A61K 31/454 (20130101) A61K 31/454 (20130101) A61K 31/498 (20130101) A61K 31/498 (20130101) A61K 31/502 (20130101) A61K 31/502 (20130101) A61K 31/517 (20130101) Original (OR) Class A61K 31/517 (20130101) A61K 31/573 (20130101) A61K 31/713 (20130101) A61K 31/713 (20130101) A61K 31/4178 (20130101) A61K 31/4178 (20130101) A61K 31/4439 (20130101) A61K 31/4439 (20130101) A61K 31/4985 (20130101) A61K 31/4985 (20130101) A61K 38/1793 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/241 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285293 | Tang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Maryland, Baltimore (Baltimore, Maryland); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | University Of Maryland, Baltimore (Baltimore, Maryland); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Cha-Min Tang (Wayne, Pennsylvania); Paul E. Bigeleisen (Baltimore, Maryland); Samuel M. Galvagno, Jr. (Baltimore, Maryland); Mark E. Shirtliff (Ellicott City, Maryland) |
| ABSTRACT | A device disclosed herein includes a tubular member which is flexible and configured to receive ultraviolet (UV) light from a UV illumination coupler. The tubular member contains a lumen defining a longitudinal interior space within the tubular member, a tubular body bounded by an inner wall defining an outer boundary of the lumen and an outer wall defining an outer surface of the tubular member, at least one optical fiber disposed outside of the interior space not parallel to an axis of the lumen and adapted to receive the UV light from the UV illumination coupler, and a protective component adapted to prevent substantively all of the UV light emitted from the optical fiber from exiting the outer wall. Methods for producing and using such devices are also disclosed herein. |
| FILED | Tuesday, December 11, 2018 |
| APPL NO | 16/216076 |
| ART UNIT | 3781 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/06 (20130101) A61L 29/06 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/04 (20130101) A61M 25/0012 (20130101) A61M 25/0017 (20130101) A61M 25/0043 (20130101) Original (OR) Class A61M 25/0045 (20130101) A61M 27/00 (20130101) A61M 2025/0056 (20130101) A61M 2202/0496 (20130101) A61M 2205/587 (20130101) Compositions of Macromolecular Compounds C08L 83/04 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49016 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285321 | Ganguly et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); U.S. Government Represented by the Department of Veterans Affairs (Washington, District of Columbia); LightSide MD, LLC (Los Altos, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); U.S. Government Represented by the Department of Veterans Affairs (Washington, District of Columbia); LightSide MD, LLC (Los Altos, California) |
| INVENTOR(S) | Karunesh Ganguly (San Francisco, California); Adelyn Tsu (San Francisco, California); Nikhilesh Natraj (San Francisco, California); Gabriel Philip Howles-Banerji (Oakland, California); Rajiv Doshi (Los Altos, California); Kondapavulur T. Venkateswara-Rao (San Jose, California) |
| ABSTRACT | Methods and apparatuses for sensory electrical stimulation of the peripheral nervous system to improve human motor function and performance are described. Methods and devices may be used to enhance physical performance of athletes, professionals, and gamers or improve motor function (hand, finger and limb movement) in patients rehabilitating from neurological deficits and impairments caused by stroke, traumatic brain injury and other neurologic or non-neurologic conditions. These apparatuses and methods may be used for physical training and mental training (to improve memory and functional performance including motor coordination, limb-eye coordination, occupational and recreational skills) through periodic or sustained sensory electrical stimulation. Treatment plans may be based on biomarkers and may be used alone or in combination with other apparatuses. Learning and feedback techniques individualize treatment parameters depending on the subject's neurologic and motor function in diseased patients and healthy users. |
| FILED | Tuesday, November 14, 2017 |
| APPL NO | 16/461085 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/002 (20130101) A61B 5/30 (20210101) A61B 5/375 (20210101) A61B 5/4047 (20130101) A61B 5/4824 (20130101) A61B 5/4848 (20130101) A61B 5/7275 (20130101) A61B 5/7455 (20130101) A61B 2505/09 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/378 (20130101) A61N 1/0456 (20130101) A61N 1/0484 (20130101) A61N 1/0492 (20130101) A61N 1/36021 (20130101) A61N 1/36031 (20170801) Original (OR) Class A61N 1/36034 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286251 | Sadeghi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yale University (New Haven, Connecticut); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Mehran Sadeghi (Bethany, Connecticut); Yunpeng Ye (Staten Island, New York); Hye-Yeong Kim (Hamden, Connecticut); Henry(Yiyun) Huang (Madison, Connecticut); Jakub Toczek (New Haven, Connecticut) |
| ABSTRACT | The present invention provides certain compounds, or salts or solvates thereof, which can be used as matrix metalloproteinase-targeted inhibitors or imaging agents. |
| FILED | Friday, April 07, 2017 |
| APPL NO | 16/088868 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/044 (20130101) Heterocyclic Compounds C07D 273/01 (20130101) C07D 413/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286525 | Tsalik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Ephraim L. Tsalik (Cary, North Carolina); Geoffrey S. Ginsburg (Durham, North Carolina); Christopher W. Woods (Durham, North Carolina); Ricardo Henao Giraldo (Durham, North Carolina); Rachel A. Myers (Raleigh, North Carolina) |
| ABSTRACT | The present disclosure provides methods for determining whether a subject has sepsis, or is at risk of developing sepsis, and methods of treating the subject based on the determination. Also provided are methods for determining an increased risk of mortality in a subject with sepsis or suspected of having sepsis, and methods of treating the subject based on the determination. Systems useful for the same are also provided. |
| FILED | Tuesday, January 16, 2018 |
| APPL NO | 16/478202 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287427 | Powers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee); THE UNITED STATES AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee); THE UNITED STATES AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Alvin C. Powers (Brentwood, Tennessee); Marcela Brissova (Nashville, Tennessee); Chunhua Dai (Nashville, Tennessee); Neil Phillips (Lawrenceville, Georgia); Diane Saunders (Nashville, Tennessee) |
| ABSTRACT | In spite of significant efforts to identify β-cell-specific markers for β-cell imaging and purification, progress has been limited. Herein is disclosed a novel biomarker of human pancreatic β-cells, CD39L3 (also known as ectonucleoside triphosphate diphosphohydrolase-3 (NTPDase3)). Disclosed are compositions and methods for purifying and imaging β-cell using anti-CD39L3 antibodies. |
| FILED | Monday, June 11, 2018 |
| APPL NO | 16/620747 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/39 (20130101) Peptides C07K 16/40 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 33/54313 (20130101) G01N 33/54326 (20130101) G01N 33/56966 (20130101) Original (OR) Class G01N 2500/10 (20130101) G01N 2800/042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11285039 | Steele et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina) |
| INVENTOR(S) | John W. Steele (New Hartford, Connecticut); Peter A. Canga (League City, Texas); Barbara M. Peyton (Windsor, Connecticut); Tony Rector (East Granby, Connecticut); Douglas Zupan (La Porte, Texas) |
| ABSTRACT | A thermal management system includes a space structure, a feed water container, a water feed line, a pump, and a filter device. The space structure includes a heat source connected with a fluid loop for conveying a working fluid through the heat source to regulate temperature and a sublimator connected with the fluid loop to receive the working fluid. The sublimator has a porous surface. The water feed line is connected with the container and the sublimator. The pump is located in the feed water line and is operable to move the feed water from the container to the sublimator. The sublimator is operable to cool the working fluid using the porous surface. The filter device is located in the water feed line between the pump and the feed water container. The filter device includes an adsorbent bed to remove organic compounds. |
| FILED | Tuesday, May 15, 2018 |
| APPL NO | 15/979673 |
| ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 7/0085 (20130101) Original (OR) Class A61F 2007/0056 (20130101) Separation B01D 7/00 (20130101) Cosmonautics; Vehicles or Equipment Therefor B64G 6/00 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/001 (20130101) C02F 1/50 (20130101) C02F 1/283 (20130101) C02F 9/005 (20130101) C02F 2101/34 (20130101) C02F 2101/40 (20130101) C02F 2101/322 (20130101) C02F 2103/023 (20130101) C02F 2303/04 (20130101) Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 5/0035 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285154 | Habib |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as Represented by The Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Amyn Aziz Habib (Dallas, Texas) |
| ABSTRACT | Provided herein are methods and pharmaceutical compositions for treating cancer, in a patient in need thereof, said method comprising administering to said patient an effective amount of an EGFR inhibitor and a TNF inhibitor. |
| FILED | Thursday, March 29, 2018 |
| APPL NO | 15/940802 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/17 (20130101) A61K 31/277 (20130101) A61K 31/277 (20130101) A61K 31/416 (20130101) A61K 31/416 (20130101) A61K 31/454 (20130101) A61K 31/454 (20130101) A61K 31/498 (20130101) A61K 31/498 (20130101) A61K 31/502 (20130101) A61K 31/502 (20130101) A61K 31/517 (20130101) Original (OR) Class A61K 31/517 (20130101) A61K 31/573 (20130101) A61K 31/713 (20130101) A61K 31/713 (20130101) A61K 31/4178 (20130101) A61K 31/4178 (20130101) A61K 31/4439 (20130101) A61K 31/4439 (20130101) A61K 31/4985 (20130101) A61K 31/4985 (20130101) A61K 38/1793 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/241 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286042 | Calkins et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Frederick Theodore Calkins (Renton, Washington); Douglas E. Nicholson (Saint Charles, Missouri); Jordan Kreitzman (Saint Charles, Missouri) |
| ABSTRACT | Variably porous panels and panel assemblies incorporating shape memory alloy components along with methods for actuating the shape memory alloys are disclosed to predictably alter the porosity of a substrate surface, with the shape memory alloy maintained in an orientation relative to the panel that is in-plane with a mold-line of the panel outer surface. |
| FILED | Friday, August 10, 2018 |
| APPL NO | 16/100412 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 61/06 (20130101) Aeroplanes; Helicopters B64C 21/02 (20130101) B64C 21/08 (20130101) Original (OR) Class B64C 21/025 (20130101) B64C 2230/20 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 2033/0206 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286067 | Weathers et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Jeffrey W. Weathers (Huntsville, Alabama); Dustin Gregory Padgett (Huntsville, Alabama) |
| ABSTRACT | A system includes a first component, a second component, a locking pin, and an interface assembly that is configured to selectively adjust a stiffness of a coupling interface between the first component and the second component. The interface assembly includes at least one support coupler secured to the first component. The support coupler(s) includes a main body, a first arm extending from a first side of the main body, a second arm extending from a second side of the main body, and a flange extending from the main body. The flange includes a locking pin hole that is configured to selectively receive the locking pin. The locking pin is selectively moveable between a retracted position in which the locking pin is out of the locking pin hole, and a deployed position in which the locking pin extends into the locking pin hole and a portion of the first component and locks the interface assembly to the first component. |
| FILED | Tuesday, October 09, 2018 |
| APPL NO | 16/154832 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/641 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286865 | Klein et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana) |
| INVENTOR(S) | Kyle Klein (Indianapolis, Indiana); Michael Karam (Plainfield, Indiana); Jonathan Sands (Clayton, Indiana) |
| ABSTRACT | A gas turbine engine includes a fan and an engine core that includes a compressor, a combustor, and a turbine. The fan and the compressor include variable pitch geometry. The gas turbine engine further includes a control system configured to adjust the variable pitch geometry of the fan and the compressor to optimize a performance characteristic of the gas turbine engine. |
| FILED | Friday, September 14, 2018 |
| APPL NO | 16/131729 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 9/20 (20130101) Original (OR) Class Jet-propulsion Plants F02K 1/66 (20130101) F02K 3/06 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2270/05 (20130101) F05D 2270/07 (20130101) F05D 2270/08 (20130101) F05D 2270/101 (20130101) F05D 2270/112 (20130101) F05D 2270/333 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11289789 | Bulcha |
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| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Berhanu T. Bulcha (Bowie, Maryland) |
| ABSTRACT | A six-pole patch bandpass filter includes a dielectric substrate and six electrically-conductive isosceles-triangle patches disposed thereon. A first pair of the patches is an electrically connected pair. The first pair of patches is capacitively coupled to a first microstrip. A second pair of the patches is also an electrically connected pair. The second pair of patches is capacitively coupled to a second microstrip. A third pair of the patches are nested between and capacitively coupled to the first pair of patches and the second pair of patches. |
| FILED | Monday, May 03, 2021 |
| APPL NO | 17/306552 |
| ART UNIT | 2843 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/203 (20130101) H01P 1/20309 (20130101) H01P 1/20381 (20130101) H01P 7/088 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 11287334 | Eckel et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland); NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Gaithersburg, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); Government of the USA, as represented by the Secretary of Commerce, National Institute of Standards and Technology (Gaithersburg, Maryland) |
| INVENTOR(S) | Stephen Eckel (Rockville, Maryland); James Fedchak (Washington, District of Columbia); Thomas Purdy (Gaithersburg, Maryland); Robinjeet Singh (Gaithersburg, Maryland) |
| ABSTRACT | An optomechanical pressure-measurement system measures pressure in the range of 10−6 Pa-10−2 Pa by measuring various properties of a vibrational mode of an ultra-thin membrane member. With independent measurements of the thickness and density of the membrane, in addition to the measured vibration mode properties, the system can operate as a primary pressure sensor. The membrane member is mounted on a vibration-isolated mount and is excited by a drive force. A laser beam impinges on the excited membrane, and an optical phase detector detects the amplitude of the oscillations, as well as parameters of the laser beam affected by the membrane vibration. In one embodiment, a mechanical damping is computed based on the amplitude or frequency shift (depending on the pressure range), and the pressure based on the ring-down time of the membrane vibration mode. |
| FILED | Wednesday, June 19, 2019 |
| APPL NO | 16/445583 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/103 (20130101) Original (OR) Class G01L 1/106 (20130101) G01L 27/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11287366 | Long et al. |
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| FUNDED BY |
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| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Christian John Long (Westminster, Colorado); Nathan Daniel Orloff (Louisville, Colorado); Nina Popovic Basta (Boulder, Colorado); Edward Joseph Garboczi (Arvada, Colorado) |
| ABSTRACT | A scanning microwave ellipsometer includes: a microwave ellipsometry test head including: a polarization controller; a transmission line; and a sensor that produces sensor microwave radiation, subjects a sample to the sensor microwave radiation, receives a sample reflected microwave radiation from the sample that results from subjecting the sample with the sample reflected microwave radiation, and produces a sensor-received microwave radiation from the sample reflected microwave radiation, wherein a polarization of the sensor microwave radiation is controlled by the polarization controller; an electrical signal measurement system that produces an electrical readout signal such that a magnitude of reflection coefficient Γ and an angle of reflection coefficient Γ of the sample reflected microwave radiation is determined from the electrical readout signal; and a position controller that adjusts a relative position of the sensor and the sample. |
| FILED | Friday, May 01, 2020 |
| APPL NO | 16/864466 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/211 (20130101) Original (OR) Class G01N 22/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11291103 | Eckel et al. |
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| FUNDED BY |
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| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Stephen Paul Eckel (Rockville, Maryland); Daniel Schaeder Barker (Berwyn Heights, Maryland); James Anthony Fedchak (Washington, District of Columbia); Julia Kay Scherschligt (Montgomery Village, Maryland); Eric Burton Norrgard (Silver Spring, Maryland); Nikolai Nikolaevich Klimov (Ellicott City, Maryland) |
| ABSTRACT | A uniaxial counter-propagating monolaser atom trap cools and traps atoms with a single a laser beam and includes: an atom slower that slows atoms to form slowed atoms; an optical diffractor including: a first diffraction grating that receives primary light and produces first reflected light; a second diffraction grating that receives primary light and produces second reflected light; and a third diffraction grating that receives the primary light and produces third reflected light; and a trapping region that forms trap light from the reflected lights and receives slowed atoms to produce trapped atoms from the slowed atoms that interact with the trap light. |
| FILED | Thursday, October 10, 2019 |
| APPL NO | 16/598144 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/42 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/08 (20130101) H01J 37/075 (20130101) H01J 2237/0815 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 3/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11285478 | Hung et al. |
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| FUNDED BY |
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| APPLICANT(S) | Combinati Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Combinati Incorporated (Carlsbad, California) |
| INVENTOR(S) | Ju-Sung Hung (Palo Alto, California); Andrew Zayac (San Leandro, California); Megan Dueck (Brisbane, California) |
| ABSTRACT | In some aspects, the present disclose provides methods for amplifying and quantifying nucleic acids. Methods for amplifying and quantifying nucleic acids comprise isolating a sample comprising nucleic acid molecules into a plurality of microchambers, performing a polymerase chain reaction on the plurality of microchambers, and analyzing the results of the polymerase chain reaction. In some aspects, the present disclosure provides devices consistent with the methods herein. |
| FILED | Friday, October 13, 2017 |
| APPL NO | 15/783743 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Original (OR) Class B01L 7/52 (20130101) B01L 2200/0605 (20130101) B01L 2300/18 (20130101) B01L 2300/0609 (20130101) B01L 2300/0851 (20130101) B01L 2300/0864 (20130101) B01L 2400/049 (20130101) B01L 2400/0487 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/686 (20130101) C12Q 2563/159 (20130101) C12Q 2565/629 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11285616 | Penning et al. |
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| FUNDED BY |
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| APPLICANT(S) | Teradyne, Inc. (North Reading, Massachusetts) |
| ASSIGNEE(S) | Teradyne, Inc. (North Reading, Massachusetts) |
| INVENTOR(S) | Ryan S. Penning (Madison, Wisconsin); Ralph F. Polimeni, Jr. (Reno, Nevada); Brett L. Limone (Danvers, Massachusetts); James D. English (Alva, Florida) |
| ABSTRACT | The specification and drawings present a robotic coating application system and a method for coating at least one part with a robotic coating application system. The robotic coating application system may comprise an enclosure configured to receive at least one part. The robotic coating application system may further comprise at least one robot configured to operate at least partially within the enclosure. The robotic coating application system may also comprise a graphical user interface to display a model of the at least one part and allow a user to select a portion or subportion of the model for application of a coating. The coating may be automatically applied to the at least one part based upon, at least in part, the user-selected portion or subportion. |
| FILED | Tuesday, September 11, 2018 |
| APPL NO | 16/127960 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 13/0431 (20130101) Apparatus for Applying Fluent Materials to Surfaces, in General B05C 5/0212 (20130101) B05C 5/0216 (20130101) B05C 9/10 (20130101) B05C 13/02 (20130101) B05C 15/00 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0081 (20130101) B25J 9/163 (20130101) B25J 11/0075 (20130101) Original (OR) Class B25J 13/06 (20130101) B25J 13/081 (20130101) B25J 15/0066 (20130101) B25J 19/022 (20130101) B25J 19/023 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11286256 | Fuller et al. |
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| FUNDED BY |
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| APPLICANT(S) | Alkermes, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | Alkermes, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Nathan Oliver Fuller (Arlington, Massachusetts); John A. Lowe, III (Stonington, Connecticut) |
| ABSTRACT | Provided herein are compounds and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of conditions associated with inhibition of HDAC (e.g,. HDAC2). |
| FILED | Thursday, May 21, 2020 |
| APPL NO | 16/880075 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/519 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11286464 | Ramamoorthy |
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| FUNDED BY |
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| APPLICANT(S) | NDSU Research Foundation (Fargo, North Dakota) |
| ASSIGNEE(S) | NDSU RESEARCH FOUNDATION (Fargo, North Dakota) |
| INVENTOR(S) | Sheela Ramamoorthy (Fargo, North Dakota) |
| ABSTRACT | Provided herein is a method for producing an inactivated virus including a) heating the virus to a temperature sufficient to disrupt the virus membrane; b) exposing the virus of step (a) to an RNA degrading enzyme; and c) cooling the virus to a temperature sufficient to reestablish the integrity of the virus membrane. Also provided herein is a vaccine produced using the instant method. |
| FILED | Tuesday, February 27, 2018 |
| APPL NO | 15/906685 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/145 (20130101) A61K 39/215 (20130101) A61K 2039/543 (20130101) A61K 2039/5252 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) A61P 31/16 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2760/16134 (20130101) C12N 2760/16163 (20130101) C12N 2770/20034 (20130101) C12N 2770/20063 (20130101) C12N 2770/24134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |