FedInvent™ Patents

Patent Details for Tuesday, March 29, 2022 

This page was updated on Wednesday, March 30, 2022 at 03:45 AM GMT

Department of Health and Human Services (HHS) 

US 11284788 Maiorano et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Children's Medical Center Corporation (Boston, Massachusetts)
ASSIGNEE(S) The Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S) Anthony Maiorano (Waltham, Massachusetts);  Jeffrey C. Cerier (Franklin, Massachusetts)
ABSTRACT In at least some aspects, an instrument port for introducing an instrument into a surgical site comprises: a port body having: an instrument channel extending through the port body; and a plurality of fluid flush channels each separate from one another and the instrument channel, each extending along a major portion of the port body and in fluid communication with the instrument channel; and a bulb comprising a bulb channel extending through the bulb, the bulb channel aligned with the instrument channel, wherein the bulb channel and instrument channel are configured to receive the instrument.
FILED Friday, March 09, 2018
APPL NO 15/916844
ART UNIT 3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/05 (20130101)
A61B 1/015 (20130101)
A61B 1/018 (20130101)
A61B 1/00066 (20130101)
A61B 1/00094 (20130101)
A61B 1/00096 (20130101)
A61B 1/00101 (20130101)
A61B 1/00119 (20130101)
A61B 1/125 (20130101)
A61B 1/126 (20130101) Original (OR) Class
A61B 1/00128 (20130101)
A61B 1/0676 (20130101)
A61B 17/3415 (20130101)
A61B 17/3421 (20130101)
A61B 17/3498 (20130101)
A61B 2017/00243 (20130101)
A61B 2017/3445 (20130101)
A61B 2217/005 (20130101)
A61B 2217/007 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11284792 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) UNIVERSITY OF WASHINGTON (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Ruikang K. Wang (Seattle, Washington);  Anqi Zhang (Seattle, Washington);  Qinqin Zhang (Seattle, Washington)
ABSTRACT Systems and methods for enhancing quality of a flow image of a sample of a subject are provided. The method comprises acquiring a first flow image from a plurality of first OMAG scans of the sample, and acquiring a structure image from a second OMAG scan of the sample. Data based on pixel intensity values from the flow image and pixel intensity values from the structure image are then plotted onto a graph and from the graph, may be differentiated into a first data group representing static structure signals and a second data group representing flow signals. The method then includes suppressing pixels in the flow image corresponding to the first data group. The flow signal may also be multiplied by a weighting factor to suppress artifacts in the image.
FILED Monday, March 07, 2016
APPL NO 15/552437
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/14 (20130101)
A61B 3/0025 (20130101)
A61B 3/102 (20130101) Original (OR) Class
A61B 3/1241 (20130101)
A61B 5/0066 (20130101)
A61B 5/0261 (20130101)
A61B 5/489 (20130101)
A61B 2576/02 (20130101)

Image Data Processing or Generation, in General
G06T 5/005 (20130101)
G06T 2207/10101 (20130101)
G06T 2207/20072 (20130101)
G06T 2207/20076 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11284823 Hobbs et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
NIH Office of the Director (NIHOD)
APPLICANT(S) Oregon Health and Science University (Portland, Oregon)
ASSIGNEE(S) Oregon Health and Science University (Portland, Oregon)
INVENTOR(S) Theodore Hobbs (Portland, Oregon);  Ravikant Samatham (Portland, Oregon);  Steven L. Jacques (Portland, Oregon)
ABSTRACT Disclosed are a method, device and system for determining total circulating blood volume (BV) using a minimally invasive technique.
FILED Thursday, December 27, 2018
APPL NO 16/233488
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0071 (20130101)
A61B 5/0075 (20130101)
A61B 5/0261 (20130101)
A61B 5/0275 (20130101)
A61B 5/1459 (20130101)
A61B 5/02028 (20130101)
A61B 5/6831 (20130101)
A61B 5/6832 (20130101)
A61B 5/6852 (20130101)
A61B 5/14535 (20130101)
A61B 5/14552 (20130101)
A61B 5/14556 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11284838 Howard et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) George Mason University (Fairfax, Virginia)
ASSIGNEE(S) George Mason University Research Foundation, Inc. (Fairfax, Virginia)
INVENTOR(S) Marissa A. Howard (Richmond, Virginia);  Lance A. Liotta (Bethesda, Maryland);  Rachel Naidich (Fairfax, Virginia);  Matthew Luu Trang (Nokesville, Virginia);  Ish Sethi (Chantilly, Virginia);  Rebecca Woodhouse (Oakton, Virginia);  Kshamata Neupane (Haymarket, Virginia)
ABSTRACT A wearable device measures, tracks, and monitors a wearer's physical physiological conditions during a rehabilitation period. Metrics such as temperature, patellar shifting, limb circumference, and acceleration may be collected. Changes in monitored conditions may be assessed for detecting medical abnormalities which require specialized attention, including for example embolisms or infections. A networked communication system and various user interfaces may be used for medical support personnel and patients alike to stay updated with the patient's rehabilitation progress and to make adjustments in a patient's individual rehabilitation program.
FILED Wednesday, October 24, 2018
APPL NO 16/169295
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/015 (20130101)
A61B 5/0024 (20130101)
A61B 5/0048 (20130101)
A61B 5/0053 (20130101)
A61B 5/112 (20130101)
A61B 5/746 (20130101)
A61B 5/1107 (20130101)
A61B 5/1114 (20130101)
A61B 5/1126 (20130101)
A61B 5/4519 (20130101)
A61B 5/4528 (20130101)
A61B 5/4585 (20130101)
A61B 5/4848 (20130101)
A61B 5/6824 (20130101)
A61B 5/6828 (20130101) Original (OR) Class
A61B 5/6829 (20130101)
A61B 5/7275 (20130101)
A61B 5/7465 (20130101)
A61B 2503/08 (20130101)
A61B 2503/10 (20130101)
A61B 2505/09 (20130101)
A61B 2562/0219 (20130101)
A61B 2562/0247 (20130101)
A61B 2562/0261 (20130101)
A61B 2562/0271 (20130101)

Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body
A61H 2230/08 (20130101)
A61H 2230/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11284851 Madabhushi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Anant Madabhushi (Shaker Heights, Ohio);  Thomas Atta-Fosu (Cleveland Heights, Ohio);  Soumya Ghose (Niskayuna, New York)
ABSTRACT Embodiments access a set of radiological images acquired from a population of subjects, where a member of the set of radiological images includes a left atrium (LA) region; construct a statistical shape differential atlas from the images; generate a template LA model from the statistical shape differential atlas, where the template LA model includes a site of interest (SOI); acquire a pre-ablation radiological image of a region of tissue in a patient demonstrating atrial fibrillation (AF) pathology; generate a patient LA model from the pre-ablation image; compute a deformation field that registers the SOI to the patient LA model using deformable registration; compute a patient feature vector based on the deformation field; generate an AF probability score for the patient based on the feature vector; generate a classification of the patient based, at least in part, on the AF probability score; and display the classification or the AF probability score.
FILED Friday, March 22, 2019
APPL NO 16/361421
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/361 (20210101)
A61B 6/032 (20130101)
A61B 6/54 (20130101)
A61B 6/463 (20130101)
A61B 6/469 (20130101)
A61B 6/503 (20130101) Original (OR) Class
A61B 6/5217 (20130101)
A61B 2018/00351 (20130101)
A61B 2018/00577 (20130101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)

Image Data Processing or Generation, in General
G06T 2207/30048 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 10/60 (20180101)
G16H 30/40 (20180101)
G16H 50/20 (20180101)
G16H 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285106 Thaxton et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) C. Shad Thaxton (Chicago, Illinois);  Chad A. Mirkin (Wilmette, Illinois);  Kaylin M. McMahon (Chicago, Illinois);  Sushant Tripathy (Evanston, Illinois);  Raja Kannan Mutharasan (Chicago, Illinois);  David M. Leander (St. Louis, Missouri);  Andrea Luthi (Evanston, Illinois)
ABSTRACT Articles, compositions, kits, and methods relating to nanostructures, including synthetic nanostructures, are provided. Certain embodiments described herein include structures having a core-shell type arrangement; for instance, a nanostructure core may surrounded by a shell including a material, such as a lipid bilayer, and may include other components such as oligonucleotides. In some embodiments, the structures, when introduced into a subject, can be used to deliver nucleic acids and/or can regulate gene expression. Accordingly, the structures described herein may be used to diagnose, prevent, treat or manage certain diseases or bodily conditions. In some cases, the structures are both a therapeutic agent and a diagnostic agent.
FILED Monday, April 15, 2019
APPL NO 16/384749
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/127 (20130101) Original (OR) Class
A61K 9/1271 (20130101)
A61K 9/5115 (20130101)
A61K 9/5123 (20130101)
A61K 31/7088 (20130101)
A61K 47/544 (20170801)
A61K 47/554 (20170801)
A61K 47/6917 (20170801)
A61K 47/6923 (20170801)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/87 (20130101)
C12N 15/111 (20130101)
C12N 2310/113 (20130101)
C12N 2310/3515 (20130101)
C12N 2320/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285137 Kolesnick et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Memorial Sloan-Kettering Cancer Center (New York, New York)
ASSIGNEE(S) MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York)
INVENTOR(S) Richard Kolesnick (New York, New York);  Adriana Haimovitz-Friedman (New York, New York);  Evis Sala (New York, New York);  Zvi Fuks (New York, New York)
ABSTRACT Disclosed is a method for enhancing tumor response to chemotherapy, the method comprising administering a short-acting anti-angiogenic agent (AAA) capable of activating ASMase to a subject afflicted with a solid tumor, and thereby creating a time interval of increased susceptibility of said tumor to one or more chemotherapeutic agents, followed by administration of at least one chemotherapeutic agent within the interval. The interval can be defined in terms of a short-duration activation of ASMase signaling by the AAA. Disclosed are also methods for predicting the tumor response in a patient afflicted with a solid tumor to a chemotherapeutic agent, using as an indicator of the response ASMase level or activity (or ceramide level) in the patient following the administration of the chemotherapeutic agent to the patient, or dynamic IVIM based DW-MRI to measure perfusion alterations following administration of the chemotherapeutic agent.
FILED Thursday, July 18, 2019
APPL NO 16/516235
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/337 (20130101)
A61K 31/337 (20130101)
A61K 31/404 (20130101)
A61K 31/404 (20130101)
A61K 31/4439 (20130101) Original (OR) Class
A61K 31/4439 (20130101)
A61K 31/7048 (20130101)
A61K 31/7048 (20130101)
A61K 31/7068 (20130101)
A61K 31/7068 (20130101)
A61K 33/24 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/485 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57488 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285142 Calakos et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) DUKE UNIVERSITY (Durham, North Carolina);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY DEPARMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  Duke University (Durham, North Carolina)
INVENTOR(S) Nicole Calakos (Chapel Hill, North Carolina);  Zachary F. Caffall (Durham, North Carolina);  Joseph Rittiner (Durham, North Carolina);  Min Shen (Boyds, Maryland);  Jennifer T. Fox (Rockville, Maryland);  Zhuyin Li (Wallingford, Connecticut)
ABSTRACT The present disclosure provides methods and compositions for the treatment, identification, diagnosis, and prognosis of dystonia, or dystonia related disorders.
FILED Thursday, September 29, 2016
APPL NO 15/764320
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/17 (20130101)
A61K 31/47 (20130101) Original (OR) Class
A61K 31/427 (20130101)
A61K 31/472 (20130101)
A61K 31/497 (20130101)
A61K 31/513 (20130101)
A61K 31/4706 (20130101)
A61K 31/4725 (20130101)
A61K 38/05 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/14 (20180101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101)
C12Q 1/6883 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6893 (20130101)
G01N 2800/52 (20130101)
G01N 2800/2835 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285144 Sundberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts);  DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts);  PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  The General Hospital Corporation (Boston, Massachusetts);  Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Thomas Sundberg (Cambridge, Massachusetts);  Alykhan Shamji (Cambridge, Massachusetts);  Ramnik Xavier (Boston, Massachusetts);  Liv Johannessen (Boston, Massachusetts);  Nathanael Gray (Boston, Massachusetts);  Bernard Khor (Boston, Massachusetts);  Jose Perez (Cambridge, Massachusetts)
ABSTRACT A method for treating inflammation and/or autoimmune diseases comprises administering to a subject in need thereof, a composition comprising a CDK8 inhibitor. In another aspect, a method for increasing IL-10 production comprises administering to a subject in need thereof a CDK8 inhibitor. In another aspect, a method for enhancing Treg cell differentiation, comprising administering a composition comprising a CDK8 inhibitor. In certain example embodiments, the subject suffers from an inflammatory bowel disease. In certain other example embodiments, the subject requires immunosuppression to prevent rejection following a transplantation procedure.
FILED Thursday, August 03, 2017
APPL NO 16/323227
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/44 (20130101)
A61K 31/58 (20130101)
A61K 31/407 (20130101)
A61K 31/444 (20130101)
A61K 31/517 (20130101)
A61K 31/4545 (20130101)
A61K 31/4709 (20130101) Original (OR) Class
A61K 31/4725 (20130101)
A61K 31/4985 (20130101)
A61K 31/5025 (20130101)
A61K 35/17 (20130101)
A61K 38/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6869 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285147 Dutta
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) WAYNE STATE UNIVERSITY (Detroit, Michigan)
ASSIGNEE(S) Wayne State University (Detroit, Michigan)
INVENTOR(S) Aloke K. Dutta (Troy, Michigan)
ABSTRACT A compound having formula I is useful for treating a neurodegenerative disease:
or a pharmaceutically acceptable salt or ester thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8 are each independently hydroxyl, C1-4 alkyl, C1-4 alkoxyl, C1-8 alkyl, C2-8 alkenyl, C2-8 alkynyl, C4-8, are specified substituents.
FILED Friday, September 06, 2019
APPL NO 16/562942
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/135 (20130101)
A61K 31/427 (20130101)
A61K 31/495 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285149 Frank et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
ASSIGNEE(S) DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
INVENTOR(S) David Frank (Lexington, Massachusetts);  Darwin Ye (Boston, Massachusetts)
ABSTRACT The present invention relates to a combination of a signal transducer and activator of transcription 3 (STAT3) activity inhibitor; and an immune checkpoint inhibitor for use in treating or preventing the hyperproliferative disorder in a subject. Preferably, the STA3 activity inhibitor is pyrimethamine or atovaquone, and the immune checkpoint inhibitor is an anti-PD1 antibody. Preferably, the hyperproliferative disorder is a glioma or a glioblastoma.
FILED Friday, July 27, 2018
APPL NO 16/633780
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0053 (20130101)
A61K 31/122 (20130101)
A61K 31/505 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/02 (20180101)

Peptides
C07K 16/2818 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285154 Habib
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Neurological Disorders and Stroke (NINDS)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) United States Government as Represented by The Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S) Amyn Aziz Habib (Dallas, Texas)
ABSTRACT Provided herein are methods and pharmaceutical compositions for treating cancer, in a patient in need thereof, said method comprising administering to said patient an effective amount of an EGFR inhibitor and a TNF inhibitor.
FILED Thursday, March 29, 2018
APPL NO 15/940802
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/17 (20130101)
A61K 31/17 (20130101)
A61K 31/277 (20130101)
A61K 31/277 (20130101)
A61K 31/416 (20130101)
A61K 31/416 (20130101)
A61K 31/454 (20130101)
A61K 31/454 (20130101)
A61K 31/498 (20130101)
A61K 31/498 (20130101)
A61K 31/502 (20130101)
A61K 31/502 (20130101)
A61K 31/517 (20130101) Original (OR) Class
A61K 31/517 (20130101)
A61K 31/573 (20130101)
A61K 31/713 (20130101)
A61K 31/713 (20130101)
A61K 31/4178 (20130101)
A61K 31/4178 (20130101)
A61K 31/4439 (20130101)
A61K 31/4439 (20130101)
A61K 31/4985 (20130101)
A61K 31/4985 (20130101)
A61K 38/1793 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/241 (20130101)
C07K 2317/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285162 Ashcraft et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) BioMimetix JV, LLC (Englewood, Colorado);  Duke University (Durham, North Carolina)
ASSIGNEE(S) BioMimetix JV, LLC (Englewood, Colorado);  Duke University (Durham, North Carolina)
INVENTOR(S) Kathleen Ashcraft (Durham, North Carolina);  Mark Dewhirst (Chapel Hill, North Carolina);  Ines Batinic-Haberle (Durham, North Carolina);  James D. Crapo (Englewood, Colorado)
ABSTRACT Described herein are methods, compositions, and kits for treating and/or preventing in a subject one or more side effects associated with radiation and/or chemotherapy exposure, including methods, compositions and kits that include an active agent at a low dose. In some embodiments, methods, compositions, and kits for treating and/or preventing tissue damage in a subject are provided, including methods, compositions and kits that include an active agent at a low dose.
FILED Wednesday, April 04, 2018
APPL NO 16/500490
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/555 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285165 DeNardo et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Sally J. DeNardo (El Macero, California);  Gerald L. DeNardo (El Macero, California);  Rodney L. Balhorn (Livermore, California)
ABSTRACT This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use of antibodies. SHALs typically comprise a multiplicity of ligands that each bind different region son the target molecule. The ligands are joined directly or through a linker thereby forming a polydentate moiety that typically binds the target molecule with high selectivity and avidity.
FILED Wednesday, April 08, 2020
APPL NO 16/843783
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/675 (20130101) Original (OR) Class
A61K 47/55 (20170801)
A61K 47/60 (20170801)
A61K 47/64 (20170801)
A61K 47/545 (20170801)
A61K 47/645 (20170801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285169 Roberts et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) David D. Roberts (Bethesda, Maryland);  David R. Soto Pantoja (Rockville, Maryland)
ABSTRACT Methods of reducing cytotoxicity of a chemotherapeutic agent to non-cancer cells by administering to a subject with cancer an effective amount of an agent that inhibits CD47 signaling and a DNA damaging agent, such as an anthracycline, topoisomerase inhibitor, or nucleotide synthesis inhibitor, are provided. Example disclosed methods reduce cardiotoxicity. In one example, the methods include administering to a subject with cancer an effective amount of a CD47 antisense morpholino oligonucleotide and an anthracycline such as doxorubicin. Methods of increasing cytotoxicity of a chemotherapeutic agent in cancer cells by administering to a subject with a tumor an effective amount of an agent that inhibits CD47 signaling and a DNA damaging agent such as an anthracycline, topoisomerase inhibitor, or nucleotide synthesis inhibitor, are also provided. In some embodiments, the inhibitor of CD47 signaling is administered to the subject before, during, or after the administration of the DNA damaging agent.
FILED Thursday, March 13, 2014
APPL NO 14/775428
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/52 (20130101)
A61K 31/52 (20130101)
A61K 31/65 (20130101)
A61K 31/65 (20130101)
A61K 31/137 (20130101)
A61K 31/137 (20130101)
A61K 31/351 (20130101)
A61K 31/365 (20130101)
A61K 31/365 (20130101)
A61K 31/437 (20130101)
A61K 31/437 (20130101)
A61K 31/505 (20130101)
A61K 31/505 (20130101)
A61K 31/513 (20130101)
A61K 31/704 (20130101)
A61K 31/704 (20130101)
A61K 31/706 (20130101)
A61K 31/706 (20130101)
A61K 31/711 (20130101)
A61K 31/711 (20130101)
A61K 31/712 (20130101)
A61K 31/712 (20130101)
A61K 31/713 (20130101) Original (OR) Class
A61K 31/787 (20130101)
A61K 31/7064 (20130101)
A61K 31/7064 (20130101)
A61K 39/39558 (20130101)
A61K 39/39558 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
A61P 39/00 (20180101)

Peptides
C07K 16/2803 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285193 Khalili et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Temple University of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
ASSIGNEE(S) Temple University of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
INVENTOR(S) Kamel Khalili (Bala Cynwyd, Pennsylvania);  Wenhui Hu (Cherry Hill, New Jersey)
ABSTRACT A method of treating a subject at risk for having a virus infection, by administering to the subject a prophylactically effective amount of a composition comprising a vector encoding a CRISPR-associated endonuclease and at least two guide RNAs, wherein the guide RNAs are complementary to two target sequences spanning from the 5′- to 3′-LTRs of the sequence in the virus, and preventing a retroviral infection.
FILED Monday, January 29, 2018
APPL NO 15/882207
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0034 (20130101)
A61K 35/12 (20130101)
A61K 38/465 (20130101) Original (OR) Class
A61K 45/06 (20130101)
A61K 48/00 (20130101)
A61K 48/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 9/22 (20130101)
C12N 15/111 (20130101)
C12N 2310/20 (20170501)
C12N 2320/30 (20130101)
C12N 2740/16063 (20130101)

Enzymes
C12Y 301/21 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285197 Jaffee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Elizabeth A. Jaffee (Lutherville, Maryland);  Tzyy-Choou Wu (Stevenson, Maryland);  Chien-Fu Hung (Timonium, Maryland);  Ralph Hruban (Baltimore, Maryland)
ABSTRACT Mesothelin can be used as an immunotherapeutic target. It induces a cytolytic T cell response. Portions of mesothelin which induce such responses are identified. Vaccines can be either polynucleotide- or polypeptide-based. Carriers for raising a cytolytic T cell response include bacteria and viruses. A mouse model for testing vaccines and other anti-tumor therapeutics and prophylactics comprises a strongly mesothelin-expressing, transformed peritoneal cell line.
FILED Tuesday, July 02, 2019
APPL NO 16/460993
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 2267/0331 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0208 (20130101) Original (OR) Class
A61K 39/001168 (20180801)
A61K 2039/52 (20130101)
A61K 2039/53 (20130101)
A61K 2039/57 (20130101)
A61K 2039/505 (20130101)
A61K 2039/522 (20130101)
A61K 2039/523 (20130101)
A61K 2039/5154 (20130101)
A61K 2039/6031 (20130101)
A61K 2039/55511 (20130101)
A61K 2039/55522 (20130101)

Peptides
C07K 7/06 (20130101)
C07K 14/4748 (20130101)
C07K 16/30 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/74 (20130101)
C12N 15/8509 (20130101)
C12N 2710/16522 (20130101)
C12N 2740/13043 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285209 Deng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S) MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York)
INVENTOR(S) Liang Deng (New York, New York);  Stewart Shuman (New York, New York);  Jedd Wolchok (New York, New York);  Taha Merghoub (New York, New York);  Weiyi Wang (New York, New York);  Peihong Dai (New York, New York);  Ning Yang (New York, New York)
ABSTRACT The present invention relates generally to the fields of oncology, virology and immunotherapy. More particularly, it concerns the use of a recombinant modified vaccinia Ankara (MVA) virus comprising an MVA harboring a human Fms-like tyrosine kinase 3 ligand (hFlt3L) (MVA-hFtl3L). The foregoing vaccinia Ankara (MVA) virus can be delivered to tumor cells of a subject afflicted with a malignant solid tumor, to treat the tumor. In a related aspect, the present disclosure concerns a recombinant modified vaccinia Ankara virus with deletion of vaccinia virulence factor E3 (MV At.E3L) modified to express human Fms-like 5 tyrosine kinase 3 ligand (hFlt3L) isolated, suitable for use as an immunotherapeutic agent against a malignant solid tumor.
FILED Friday, April 10, 2020
APPL NO 16/845809
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 35/768 (20130101)
A61K 39/0011 (20130101)
A61K 39/3955 (20130101) Original (OR) Class
A61K 39/3955 (20130101)
A61K 2039/505 (20130101)
A61K 2039/55522 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/521 (20130101)
C07K 16/2818 (20130101)
C07K 16/2827 (20130101)
C07K 2317/76 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 2710/24032 (20130101)
C12N 2710/24121 (20130101)
C12N 2710/24132 (20130101)
C12N 2710/24143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285211 Fahmy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S) Tarek Fahmy (Middlefield, Connecticut);  Albert Sinusas (Guilford, Connecticut);  Jung Seok Lee (New Haven, Connecticut);  Dongin Kim (Glastonbury, Connecticut);  Anthony Mathur (London, United Kingdom);  John Martin (London, United Kingdom)
ABSTRACT It has been discovered that iron-platinum ferromagnetic particles can be dispersed in a polymer and coated into or onto, or directly linked to or embedded on to, medical devices and magnetized. The magnetized devices are used to attract, capture, and/or retain magnetically labeled cells on the surface of the device in vivo. The magnetic particles have an iron/platinum core. Annealing the Fe/Pt particle is very important for introducing a L10 interior crystalline phase. The Fe:Pt molar ratio for creation of the crystal phase is important and a molar range of 1.2-3.0 Fe to Pt (molar precursors, i.e. starting compounds) is desired for magnetization. The magnetic force as a whole can be measured with a “Super Conducting Quantum Interference Device”, which is a sensitive magnetometer. The overall magnetic force is in the range from 0.1 to 2.0 Tesla.
FILED Wednesday, April 01, 2015
APPL NO 15/563398
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/82 (20130101)
A61F 2210/009 (20130101)
A61F 2210/0076 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 35/44 (20130101)
A61K 35/545 (20130101)
A61K 41/0052 (20130101) Original (OR) Class

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/06 (20130101)
A61L 27/18 (20130101)
A61L 27/025 (20130101)
A61L 27/34 (20130101)
A61L 27/042 (20130101)
A61L 27/047 (20130101)
A61L 27/58 (20130101)
A61L 27/306 (20130101)
A61L 31/06 (20130101)
A61L 31/10 (20130101)
A61L 31/022 (20130101)
A61L 31/028 (20130101)
A61L 31/088 (20130101)
A61L 31/148 (20130101)
A61L 2400/18 (20130101)
A61L 2420/02 (20130101)
A61L 2420/06 (20130101)
A61L 2420/08 (20130101)
A61L 2430/20 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 2/002 (20130101)
A61N 2/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285212 Davis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) California Institute Of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Mark E. Davis (Pasadena, California);  Han Han (Belmont, California)
ABSTRACT Described herein are carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a nitroboronic boronic acid and a linkage cleavable under reducing conditions, configured to present the polymer containing the nitroboronic acid to an environment external to the nanoparticle. Targeted versions of the described nanoparticles are also described, as are related compositions, methods and systems.
FILED Monday, November 26, 2018
APPL NO 16/200095
ART UNIT 1699 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5161 (20130101)
A61K 31/337 (20130101)
A61K 31/337 (20130101)
A61K 31/727 (20130101)
A61K 31/727 (20130101)
A61K 31/4745 (20130101)
A61K 31/4745 (20130101)
A61K 45/06 (20130101) Original (OR) Class
A61K 47/60 (20170801)
A61K 47/6935 (20170801)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285227 Babich et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S) CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) John W. Babich (New York, New York);  James M. Kelly (New York, New York);  Alejandro Amor-Coarasa (New York, New York);  Shashikanth Ponnala (New York, New York)
ABSTRACT The present technology provides compounds, as well as compositions including such compounds, useful for imaging and/or treatment of a glioma, a breast cancer, an adrenal cortical cancer, a cervical carcinoma, a vulvar carcinoma, an endometrial carcinoma, a primary ovarian carcinoma, a metastatic ovarian carcinoma, a non-small cell lung cancer, a small cell lung cancer, a bladder cancer, a colon cancer, a primary, gastric adenocarcinoma, a primary colorectal adenocarcinoma, a renal cell carcinoma, and/or a prostate cancer. The compounds are represented by the following formula: (I) or a pharmaceutically acceptable salt thereof.
FILED Thursday, April 05, 2018
APPL NO 16/500380
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 51/065 (20130101) Original (OR) Class
A61K 51/0402 (20130101)
A61K 51/0497 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/04 (20180101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 59/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285318 Tai
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Changfeng Tai (Wexford, Pennsylvania)
ABSTRACT Provided herein are methods for treating underactive bladder, urinary retention, detrusor-sphincter dyssynergia after spinal cord injury, constipation, and/or infrequent bowel movements including the step of applying electrical stimulation to one or more peripheral nerves.
FILED Wednesday, May 02, 2018
APPL NO 16/609883
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0456 (20130101)
A61N 1/36007 (20130101) Original (OR) Class
A61N 1/36034 (20170801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285325 Danilov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Yuri P. Danilov (Middleton, Wisconsin);  Mitchell E. Tyler (Madison, Wisconsin);  Kurt A. Kaczmarek (Madison, Wisconsin)
ASSIGNEE(S)
INVENTOR(S) Yuri P. Danilov (Middleton, Wisconsin);  Mitchell E. Tyler (Madison, Wisconsin);  Kurt A. Kaczmarek (Madison, Wisconsin)
ABSTRACT In a patient suffering from neural impairment, stimulation is provided to sensory surfaces of the face and/or neck, or more generally to areas of the body that stimulate the trigeminal nerve, while performing an activity intended to stimulate a brain function to be rehabilitated. The simulation may then be continued after the performance of the activity has ceased. It has been found that the patient's performance of the activity is then improved after stimulation has ceased. Moreover, it tends to improve to a greater extent, and/or for a longer time, when the post-activity stimulation is applied, as compared to when post activity stimulation is not applied.
FILED Monday, June 24, 2019
APPL NO 16/450915
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body
A61H 21/00 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/361 (20130101)
A61N 1/0456 (20130101)
A61N 1/0476 (20130101)
A61N 1/0492 (20130101)
A61N 1/0526 (20130101)
A61N 1/0548 (20130101)
A61N 1/36014 (20130101)
A61N 1/36025 (20130101)
A61N 1/36067 (20130101)
A61N 1/36078 (20130101)
A61N 1/36082 (20130101)
A61N 1/36092 (20130101)
A61N 1/36096 (20130101)
A61N 1/36103 (20130101) Original (OR) Class

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 19/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285337 Vartanian et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Garen V. Vartanian (Ann Arbor, Michigan);  Kwoon Y. Wong (Ann Arbor, Michigan);  Pei-Cheng Ku (Ann Arbor, Michigan);  Scott A. Almburg (Redford Township, Michigan)
ABSTRACT A light source and a method of generating a light using the light source is disclosed. The light source is configured to produce a plurality of distinct colors in generating the light, one of the distinct colors falling within a blue spectral light band. A light controller modulates the spectral light produced by the plurality of distinct colors. The modulation provides melanopsin contrast in order to increase melanopsin responsiveness of a subject exposed to the generated light and maintains the color temperature, color quality, and color constancy experienced by the subject in a lit viewing environment within an acceptable range.
FILED Monday, July 24, 2017
APPL NO 15/658338
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/0618 (20130101) Original (OR) Class
A61N 5/0622 (20130101)
A61N 2005/0626 (20130101)
A61N 2005/0652 (20130101)
A61N 2005/0663 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285340 Larkin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) RefleXion Medical, Inc. (Hayward, California)
ASSIGNEE(S) RefleXion Medical, Inc. (Hayward, California)
INVENTOR(S) David Larkin (Menlo Park, California);  William Knapp (El Granada, California);  Layton Hale (Castro Valley, California)
ABSTRACT Described herein are multi-leaf collimators that comprise leaf drive mechanisms. The leaf drive mechanisms can be used in binary multi-leaf collimators used in emission-guided radiation therapy. One variation of a multi-leaf collimator comprises a pneumatics-based leaf drive mechanism. Another variation of a multi-leaf collimator comprises a spring-based leaf drive mechanism having a spring resonator.
FILED Thursday, November 07, 2019
APPL NO 16/677200
ART UNIT 2881 — Optics
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/1045 (20130101) Original (OR) Class
A61N 2005/1074 (20130101)

Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes
G21K 1/046 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285478 Hung et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Combinati Incorporated (Palo Alto, California)
ASSIGNEE(S) Combinati Incorporated (Carlsbad, California)
INVENTOR(S) Ju-Sung Hung (Palo Alto, California);  Andrew Zayac (San Leandro, California);  Megan Dueck (Brisbane, California)
ABSTRACT In some aspects, the present disclose provides methods for amplifying and quantifying nucleic acids. Methods for amplifying and quantifying nucleic acids comprise isolating a sample comprising nucleic acid molecules into a plurality of microchambers, performing a polymerase chain reaction on the plurality of microchambers, and analyzing the results of the polymerase chain reaction. In some aspects, the present disclosure provides devices consistent with the methods herein.
FILED Friday, October 13, 2017
APPL NO 15/783743
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/50273 (20130101) Original (OR) Class
B01L 7/52 (20130101)
B01L 2200/0605 (20130101)
B01L 2300/18 (20130101)
B01L 2300/0609 (20130101)
B01L 2300/0851 (20130101)
B01L 2300/0864 (20130101)
B01L 2400/049 (20130101)
B01L 2400/0487 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/686 (20130101)
C12Q 2563/159 (20130101)
C12Q 2565/629 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286182 Ball
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) OXYTEC LLC (Newton, Massachusetts)
ASSIGNEE(S) OXYTEC LLC (Newton, Massachusetts)
INVENTOR(S) Raymond G. Ball (Newton, Massachusetts)
ABSTRACT Disclosed are methods, apparatuses and systems for the remediation of contaminated soils, groundwater, water, and/or waste using a combination of reagents. The disclosed methods may be used to treat various recalcitrant halogenated substances, such as perfluoroalkyls and polyfluoroalkyls. Particular combinations of reagents that may be used in the disclosed methods include but are not limited to: (1) persulfate, oxygen and ozone; (2) persulfate, salt, oxygen and ozone; (3) persulfate, phosphate, and/or oxygen; (4) persulfate, phosphate, oxygen and ozone; (5) persulfate, phosphate, salt and oxygen (6) persulfate, phosphate, salt, oxygen and ozone; (7) oxygen and salt; and (8) air and salt. The disclosed methods may enhance destruction of organic contaminants in the liquid phase and may also control the rate of aerosol or foam formation relative to the rate of chemical oxidation and/or reduction/transfer.
FILED Monday, March 29, 2021
APPL NO 17/216089
ART UNIT 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Reclamation of Contaminated Soil
B09C 1/002 (20130101)
B09C 1/06 (20130101)
B09C 1/08 (20130101)
B09C 2101/00 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/32 (20130101)
C02F 1/70 (20130101)
C02F 1/78 (20130101)
C02F 1/722 (20130101) Original (OR) Class
C02F 1/725 (20130101)
C02F 1/727 (20130101)
C02F 2101/34 (20130101)
C02F 2101/36 (20130101)
C02F 2101/305 (20130101)
C02F 2101/306 (20130101)
C02F 2101/322 (20130101)
C02F 2101/327 (20130101)
C02F 2101/363 (20130101)
C02F 2103/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286251 Sadeghi et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Yale University (New Haven, Connecticut);  The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) YALE UNIVERSITY (New Haven, Connecticut);  THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S) Mehran Sadeghi (Bethany, Connecticut);  Yunpeng Ye (Staten Island, New York);  Hye-Yeong Kim (Hamden, Connecticut);  Henry(Yiyun) Huang (Madison, Connecticut);  Jakub Toczek (New Haven, Connecticut)
ABSTRACT The present invention provides certain compounds, or salts or solvates thereof, which can be used as matrix metalloproteinase-targeted inhibitors or imaging agents.
FILED Friday, April 07, 2017
APPL NO 16/088868
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 51/044 (20130101)

Heterocyclic Compounds
C07D 273/01 (20130101)
C07D 413/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286256 Fuller et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Alkermes, Inc. (Waltham, Massachusetts)
ASSIGNEE(S) Alkermes, Inc. (Waltham, Massachusetts)
INVENTOR(S) Nathan Oliver Fuller (Arlington, Massachusetts);  John A. Lowe, III (Stonington, Connecticut)
ABSTRACT Provided herein are compounds and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of conditions associated with inhibition of HDAC (e.g,. HDAC2).
FILED Thursday, May 21, 2020
APPL NO 16/880075
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/437 (20130101)
A61K 31/519 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/28 (20180101)

Heterocyclic Compounds
C07D 471/04 (20130101) Original (OR) Class
C07D 487/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286270 Hecker et al.
FUNDED BY
Department of Health and Human Services (HHS)
Assistant Secretary for Preparedness and Response (ASPR)
Biomedical Advanced Research and Development Authority (BARDA)
APPLICANT(S) Qpex Biopharma, Inc. (San Diego, California)
ASSIGNEE(S) Qpex Biopharma, Inc. (San Diego, California)
INVENTOR(S) Scott J. Hecker (Del Mar, California);  Serge Henri Boyer (San Diego, California);  Hubertus J. A. Dielemans (Beek, Netherlands);  Angela Gonzalez de Castro (Maastricht, Netherlands);  Andreas H. M. de Vries (Maastricht, Netherlands);  Laurent Lefort (Maastricht, Netherlands)
ABSTRACT Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the method of use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents, for example, β-lactamase inhibitors (BLIs).
FILED Wednesday, October 10, 2018
APPL NO 16/755138
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/44 (20130101)
B01J 23/755 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 5/025 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286279 Franco
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Alessandra Franco (San Diego, California)
ABSTRACT Provided are compositions, including isolated, synthetic or recombinant peptides for: expanding regulatory T cells (Treg) populations; for treating or ameliorating a vascular inflammation, and Kawasaki disease (KD) or a pediatric acute vasculitis of the coronary arteries, including vascular coronary abnormalities, and acute or chronic vascular inflammatory abnormalities, and method for making and using them. Provided are immunotherapies for promoting expansion of natural, Treg to establish, or re-establish, vascular homeostasis; or, for ameliorating: a disease or condition associated with an autoimmune disease or condition; as immune-mediated vascular disorder; a disease or condition treated with intravenous immunoglobulin (IVIG) therapy; a vascular coronary abnormality; an acute or a chronic vasculitis; an autoimmune vasculitis; Kawasaki disease (KD) or a pediatric acute vasculitis of the coronary arteries; atherosclerosis; preventing miscarriage in autoimmune women; rheumatoid arthritis or Juvenile Idiopathic Arthritis; a neoplastic hematological disorder, or a leukemia.
FILED Monday, August 10, 2020
APPL NO 16/989816
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/14 (20130101)
A61K 9/127 (20130101)
A61K 38/00 (20130101)
A61K 39/0005 (20130101)
A61K 39/0008 (20130101)
A61K 2039/545 (20130101)

Peptides
C07K 7/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286287 Deslouches et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
ASSIGNEE(S) UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
INVENTOR(S) Berthony Deslouches (Pittsburgh, Pennsylvania);  Yuanpu Di (Wexford, Pennsylvania)
ABSTRACT This disclosure is directed to compositions comprised of antimicrobial peptides (AMPs) having an alpha helical structure wherein one side is highly hydrophobic. Representative sequences of the antimicrobial peptides include ILKKWWββαβGLLGβLLGαVββVIKβLββI (SEQ ID No. 2), LKKWWKβαKGLLGGLLGKVββVIK (SEQ ID No. 12), and αKKααKKαKGαLGGLαGK (SEQ ID No. 18). Additional embodiments disclose methods for treating a microbial infection; reducing biofilm; decreasing inflammation; and treating infectious diseases, COPD, asthma, pulmonary fibrosis, cystic fibrosis, rhinosinusitis, septicemia, RSV, TB or cancer; in a subject in need thereof comprising administering to the subject a therapeutic amount of an antimicrobial peptide.
FILED Tuesday, November 21, 2017
APPL NO 16/462586
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 14/4723 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286299 Xue et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Trustees of Dartmouth College (Hanover, New Hampshire)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Trustees of Darthmouth College (Hanover, New Hampshire)
INVENTOR(S) Vincent Xue (Somerville, Massachusetts);  Justin Michael Jenson (Cambridge, Massachusetts);  Amy E. Keating (Arlington, Massachusetts);  Jianfu Zhou (White River Junction, Vermont);  Gevorg Grigoryan (Hanover, New Hampshire)
ABSTRACT Provided herein are peptides selective for combinations of Mcl-1/Bfl-1/Bcl-xL. Also provided are compositions containing these polypeptides and methods of using such peptides in the treatment of cancer that include administering to a subject one of the polypeptides.
FILED Tuesday, September 17, 2019
APPL NO 16/573881
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 16/28 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/53 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286301 Wernig et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Gerlinde Wernig (Stanford, California);  Irving L. Weissman (Stanford, California)
ABSTRACT Compositions and methods are provided for treating fibrosis in a mammal by administering a therapeutic dose of a pharmaceutical composition.
FILED Wednesday, February 28, 2018
APPL NO 16/487051
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1774 (20130101)
A61K 39/3955 (20130101)
A61K 45/06 (20130101)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 1/16 (20180101)
A61P 11/00 (20180101)

Peptides
C07K 16/2803 (20130101) Original (OR) Class
C07K 16/2896 (20130101)
C07K 2317/76 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/53 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286461 Visconti et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Pablo E. Visconti (Amherst, Massachusetts);  Felipe Navarrete (Hadley, Massachusetts)
ABSTRACT Methods for improving the functionality and/or fertility of sperm, for example, by enhancing motility and/or extending the lifespan of sperm by subjecting the isolated sperm to a starvation protocol and/or ionophore are provided. Such methods may be used in, for example, artificial insemination to reduce the number of sperm needed for insemination and to improve conception rates.
FILED Friday, March 31, 2017
APPL NO 16/089862
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 1/0205 (20130101)

Diagnosis; Surgery; Identification
A61B 17/43 (20130101)
A61B 17/435 (20130101)

Veterinary Instruments, Implements, Tools, or Methods
A61D 19/02 (20130101)
A61D 19/04 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 48/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/061 (20130101)
C12N 5/0604 (20130101) Original (OR) Class
C12N 15/00 (20130101)
C12N 2501/998 (20130101)
C12N 2501/999 (20130101)
C12N 2517/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286462 Nishimune et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of Kansas (Lawrence, Kansas)
ASSIGNEE(S) University of Kansas (Lawrence, Kansas)
INVENTOR(S) Hiroshi Nishimune (Kansas City, Missouri);  Richard Barohn (Kansas City, Missouri);  Buddhadeb Dawn (Mission Hills, Kansas);  Yomna Badawi (Leawood, Kansas);  James W. Mitchell (Overland Park, Kansas);  Rupal Soder (Prairie Village, Kansas)
ABSTRACT Embodiments of the present disclosure relate generally to the production of therapeutic mesenchymal stem cells (MSCs). More particularly, the present disclosure relates to the use of cell culture compositions and methods for generating MSCs that secrete neurotrophic factors and synaptic organizing agents for the treatment of neurodegenerative diseases such as Amyotrophic Lateral Sclerosis (ALS). As such, the present disclosure addresses the need for establishing a reliable source of therapeutic stem cells useful for the treatment of neurodegenerative diseases.
FILED Friday, September 14, 2018
APPL NO 16/647345
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/51 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0668 (20130101) Original (OR) Class
C12N 2500/32 (20130101)
C12N 2501/10 (20130101)
C12N 2501/13 (20130101)
C12N 2501/105 (20130101)
C12N 2501/115 (20130101)
C12N 2501/135 (20130101)
C12N 2501/165 (20130101)
C12N 2533/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286468 Joung et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) J. Keith Joung (Winchester, Massachusetts);  Benjamin Kleinstiver (Medford, Massachusetts)
ABSTRACT Engineered CRISPR-Cas9 nucleases with altered and improved PAM specificities and their use in genomic engineering, epigenomic engineering, and genome targeting.
FILED Wednesday, August 22, 2018
APPL NO 16/109657
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 2319/71 (20130101)
C07K 2319/80 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101) Original (OR) Class
C12N 9/0071 (20130101)
C12N 9/78 (20130101)
C12N 9/80 (20130101)
C12N 9/1007 (20130101)
C12N 9/1029 (20130101)
C12N 15/11 (20130101)
C12N 15/907 (20130101)
C12N 2310/20 (20170501)
C12N 2800/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286469 Raines et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S) Ronald T. Raines (Madison, Wisconsin);  Trish Hoang (Madison, Wisconsin)
ABSTRACT The present disclosure provides compositions, methods and kits for the treatment of cancer. Particularly, the present disclosure provides synergistic compositions comprising at least one cytotoxic ribonuclease and at least one MAPK-pathway inhibitor.
FILED Thursday, November 08, 2018
APPL NO 16/184629
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/519 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/04 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101) Original (OR) Class

Enzymes
C12Y 301/27005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286470 Chavez et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Alejandro Chavez (New York, New York);  Frank J. Poelwijk (Dallas, Texas);  George M. Church (Brookline, Massachusetts)
ABSTRACT Methods of making mutant Cas9 proteins are described.
FILED Monday, April 20, 2020
APPL NO 16/852592
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6897 (20130101)

Enzymes
C12Y 301/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/573 (20130101)
G01N 2333/922 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286473 Dong et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Children's Medical Center Corporation (Boston, Massachusetts);  Paul Stenmark (Stockholm, Sweden)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S) Min Dong (Weatogue, Connecticut);  Sicai Zhang (Boston, Massachusetts);  Paul Stenmark (Stockholm, Sweden)
ABSTRACT Provided herein are Clostridial Botulinum neurotoxin (BoNT) polypeptides of a novel serotype (BoNT/X) and methods of making and using the BoNT polypeptides, e.g., in therapeutic applications.
FILED Friday, July 07, 2017
APPL NO 16/315698
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 38/00 (20130101)

Peptides
C07K 14/33 (20130101)
C07K 2319/01 (20130101)
C07K 2319/21 (20130101)
C07K 2319/22 (20130101)
C07K 2319/23 (20130101)
C07K 2319/24 (20130101)
C07K 2319/035 (20130101)
C07K 2319/41 (20130101)
C07K 2319/42 (20130101)
C07K 2319/43 (20130101)
C07K 2319/50 (20130101)
C07K 2319/55 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/52 (20130101) Original (OR) Class

Enzymes
C12Y 304/24069 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286478 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of Mental Health (NIMH)
APPLICANT(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Feng Zhang (Cambridge, Massachusetts);  Bernd Zetsche (Gloucester, Massachusetts);  Winston Yan (Brookline, Massachusetts);  Neville Espi Sanjana (New York, New York);  Sara Jones (Cambridge, Massachusetts)
ABSTRACT The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA-targeting systems comprising a novel DNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA.
FILED Wednesday, April 19, 2017
APPL NO 16/095253
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/63 (20130101)
C12N 15/102 (20130101) Original (OR) Class
C12N 15/113 (20130101)
C12N 15/907 (20130101)
C12N 2310/20 (20170501)

Enzymes
C12Y 305/04005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286502 Garg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Texas Tech University System (Lubbock, Texas)
ASSIGNEE(S) Texas Tech University System (Lubbock, Texas)
INVENTOR(S) Himanshu Garg (El Paso, Texas);  Anjali Joshi (El Paso, Texas)
ABSTRACT The present invention includes compositions, methods, vectors, vaccines, cell lines and other constructs for making and used Zika virus Reporter Virus Particles (RVPs) and/or Virus Like Particles (VLPs) that are safe for handling and manufacturing and are able to generate an effective immune response against Zika virus and can be readily scaled up for cost-effective production.
FILED Wednesday, June 20, 2018
APPL NO 16/620581
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101) Original (OR) Class
C12N 2740/15043 (20130101)
C12N 2770/24122 (20130101)
C12N 2770/24123 (20130101)
C12N 2770/24134 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/70 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286514 Leng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Fenfei Leng (Palmetto Bay, Florida);  Zifang Deng (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Fenfei Leng (Palmetto Bay, Florida);  Zifang Deng (Miami, Florida)
ABSTRACT The present invention provides assays and methods for studying DNA topology and topoisomerases. The assays and methods utilize a circular plasmid DNA comprising one or more hairpin structures and the ability of T5 exonuclease (T5E) to digest the circular plasmid DNA in a specific configuration. The assays and methods can be used as a high throughput screening for inhibitors of, for example, DNA gyrases and DNA topoisomerases I for anticancer drug and antibiotics discovery.
FILED Friday, October 16, 2020
APPL NO 17/072502
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/44 (20130101)
C12Q 1/533 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6428 (20130101)
G01N 2021/6439 (20130101)
G01N 2500/04 (20130101)
G01N 2500/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286515 Chee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Prognosys Biosciences, Inc. (San Diego, California)
ASSIGNEE(S) Prognosys Biosciences, Inc. (San Diego, California)
INVENTOR(S) Mark S. Chee (San Diego, California);  David A. Routenberg (San Diego, California)
ABSTRACT The present disclosure provides methods and assay systems for use in spatially encoded biological assays, including assays to determine a spatial pattern of abundance, expression, and/or activity of one or more biological targets across multiple sites in a sample. In particular, the biological targets comprise proteins, and the methods and assay systems do not depend on imaging techniques for the spatial information of the targets. The present disclosure provides methods and assay systems capable of high levels of multiplexing where reagents are provided to a biological sample in order to address tag the sites to which reagents are delivered; instrumentation capable of controlled delivery of reagents; and a decoding scheme providing a readout that is digital in nature.
FILED Friday, June 25, 2021
APPL NO 17/358280
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5027 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6809 (20130101) Original (OR) Class
C12Q 1/6809 (20130101)
C12Q 2565/513 (20130101)
C12Q 2565/629 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286517 Kishi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Jocelyn Yoshiko Kishi (Boston, Massachusetts);  Thomas E. Schaus (Arlington, Massachusetts);  Peng Yin (Brookline, Massachusetts);  Feng Xuan (Boston, Massachusetts);  Nikhil Gopalkrishnan (Jamaica Plain, Massachusetts);  Sungwook Woo (Chestnut Hill, Massachusetts)
ABSTRACT The present disclosure provides, in some aspects, nucleic acid-based molecular tools that enable the recording of molecular structure and soluble signals as well as the programmed assembly of molecular structures.
FILED Thursday, February 16, 2017
APPL NO 15/999245
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/64 (20130101)
C12N 15/113 (20130101)
C12N 2310/122 (20130101)
C12N 2310/127 (20130101)
C12N 2330/50 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)
C12Q 1/6806 (20130101)
C12Q 1/6809 (20130101)
C12Q 1/6811 (20130101) Original (OR) Class
C12Q 1/6825 (20130101)
C12Q 1/6825 (20130101)
C12Q 1/6853 (20130101)
C12Q 1/6853 (20130101)
C12Q 2525/155 (20130101)
C12Q 2525/155 (20130101)
C12Q 2525/186 (20130101)
C12Q 2525/186 (20130101)
C12Q 2525/204 (20130101)
C12Q 2525/204 (20130101)
C12Q 2525/301 (20130101)
C12Q 2525/301 (20130101)
C12Q 2525/301 (20130101)
C12Q 2531/101 (20130101)
C12Q 2531/101 (20130101)
C12Q 2531/119 (20130101)
C12Q 2531/119 (20130101)
C12Q 2531/119 (20130101)
C12Q 2533/101 (20130101)
C12Q 2533/101 (20130101)
C12Q 2537/16 (20130101)
C12Q 2537/16 (20130101)
C12Q 2537/149 (20130101)
C12Q 2537/149 (20130101)
C12Q 2537/157 (20130101)
C12Q 2537/157 (20130101)
C12Q 2537/163 (20130101)
C12Q 2537/163 (20130101)
C12Q 2537/1373 (20130101)
C12Q 2537/1373 (20130101)
C12Q 2537/1376 (20130101)
C12Q 2537/1376 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286518 Beckman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S) Kenneth Beckman (Saint Paul, Minnesota);  Daryl Gohl (Minneapolis, Minnesota)
ABSTRACT Analytical standards can allow one to detect and/or measure sampling, processing, and/or amplification errors in a sample that includes a plurality of polynucleotide molecules. The analytical standards can provide an internal control to detect errors in the representation of the original sample reflected in data obtained after manipulating and/or processing of sample molecules.
FILED Friday, May 05, 2017
APPL NO 16/099229
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101)
C12Q 1/6848 (20130101) Original (OR) Class
C12Q 1/6869 (20130101)
C12Q 1/6869 (20130101)
C12Q 2545/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286523 Xie et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Xiaoliang Sunney Xie (Lexington, Massachusetts);  Katsuyuki Shiroguchi (Arlington, Massachusetts);  Peter A. Sims (Cambridge, Massachusetts);  Tony Z. Jia (Cambridge, Massachusetts)
ABSTRACT Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided.
FILED Tuesday, January 28, 2020
APPL NO 16/774104
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1065 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6853 (20130101)
C12Q 1/6853 (20130101)
C12Q 1/6874 (20130101) Original (OR) Class
C12Q 2525/131 (20130101)
C12Q 2525/301 (20130101)
C12Q 2537/16 (20130101)
C12Q 2563/179 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286529 Storch
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Gregory Storch (Saint Louis, Missouri)
ABSTRACT Disclosed are methods of diagnosis of a pathogen-associated disease. These methods comprise: providing a biological sample from a human subject; determining presence, absence and/or quantity of a bacterial pathogen, a viral pathogen, or a combination thereof, by a pathogen culture, a serum antibody detection test, a pathogen antigen detection test, a pathogen DNA and/or RNA detection test, or a combination thereof; determining in the sample, expression levels of at least one endogenous gene in which aberrant expression levels are associated with infection with a pathogen, by a microarray hybridization assay, RNA-seq assay, polymerase chain reaction assay, a LAMP assay, a ligase chain reaction assay, a Southern, Northern, or Western blot assay, an ELISA or a combination thereof. The subject can be diagnosed with the disease if the subject comprises the pathogen and an aberrant level of expression of an endogenous gene.
FILED Friday, February 21, 2020
APPL NO 16/797733
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/00 (20130101)
A61K 45/00 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/04 (20130101)
C12Q 1/70 (20130101)
C12Q 1/689 (20130101)
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/112 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56911 (20130101)
G01N 33/56983 (20130101)
G01N 2469/10 (20130101)
G01N 2469/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286531 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Yuxuan Wang (Baltimore, Maryland);  Bert Vogelstein (Baltimore, Maryland);  Kenneth W. Kinzler (Baltimore, Maryland);  Luis Diaz (Ellicot City, Maryland);  Nickolas Papadopoulos (Towson, Maryland);  Karin Sundfeldt (Gothenburg, Sweden);  Bjorg Kristjansdottir (Gothenburg, Sweden)
ABSTRACT A diagnostic test for ovarian cysts is based on the detection of mutations characteristic of the most common neoplasms giving rise to these lesions. With this test, tumor-specific mutations were detected in the cyst fluids of 19 of 24 (79%) borderline tumors and 28 of 31 (90%) malignant ovarian cancers. In contrast, we detected no mutations in the cyst fluids from 10 non-neoplastic cysts and 12 benign tumors. When categorized by the need for exploratory surgery (i.e., presence of a borderline tumor or malignant cancer), the sensitivity of this test was 85% and the specificity was 100%. These tests could inform the diagnosis of ovarian cysts and improve the clinical management of the large number of women with these lesions.
FILED Thursday, August 11, 2016
APPL NO 15/749887
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/156 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287414 Ouyang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Zheng Ouyang (West Lafayette, Indiana);  He Wang (West Lafayette, Indiana);  Nicholas E. Manicke (West Lafayette, Indiana);  Robert Graham Cooks (West Lafayette, Indiana);  Qian Yang (West Lafayette, Indiana);  Jiangjiang Liu (West Lafayette, Indiana)
ABSTRACT The invention generally relates to a sample dispenser including an internal standard and methods of use thereof.
FILED Thursday, July 23, 2020
APPL NO 16/936683
ART UNIT 2881 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/10 (20130101)
G01N 1/28 (20130101)
G01N 1/286 (20130101)
G01N 33/491 (20130101)
G01N 33/492 (20130101) Original (OR) Class
G01N 33/48714 (20130101)
G01N 33/48785 (20130101)
G01N 2001/2893 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 49/0009 (20130101)
H01J 49/16 (20130101)
H01J 49/0027 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287444 Lal et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Ratneshwar Lal (La Jolla, California);  Qingqing Yang (San Diego, California);  Qian Ma (San Diego, California);  Zhaowei Liu (San Diego, California)
ABSTRACT Disclosed is an atomic force microscopy system includes a laser source configured to generate an optical probe beam containing light of different spectral light components at different optical wavelengths, a dispersive optical device positioned to receive the optical probe beam and configured to disperse the optical probe beam into different dispersed light beams that are at different optical wavelengths and are spatially separated from one another, a cantilever array including a plurality of cantilevers structured to detect a sample and configured to deflect the different dispersed light beams by moving in position based on an interaction with the sample to produce multiple deflected output beams at different output optical wavelengths from the cantilevers, and a plurality of photodetectors to receive the multiple deflected output beams of different wavelengths from the cantilevers, respectively.
FILED Tuesday, October 08, 2019
APPL NO 17/283929
ART UNIT 2881 — Optics
CURRENT CPC
Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM]
G01Q 20/02 (20130101) Original (OR) Class
G01Q 60/40 (20130101)
G01Q 60/42 (20130101)
G01Q 70/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287540 Olcott et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) RefleXion Medical, Inc. (Hayward, California)
ASSIGNEE(S) RefleXion Medical, Inc. (Hayward, California)
INVENTOR(S) Peter Demetri Olcott (Los Gatos, California);  Matthew Francis Bieniosek (Danville, California);  Brent Harper (New Glarus, Wisconsin)
ABSTRACT Disclosed herein are methods and devices for the acquisition of positron emission (or PET) data in the presence of ionizing radiation that causes afterglow of PET detectors. In one variation, the method comprises adjusting a coincidence trigger threshold of the PET detectors during a therapy session. In one variation, the method comprises adjusting a gain factor used in positron emission data acquisition (e.g., a gain factor used to multiply and/or shift the output(s) of a PET detector(s)) during a therapy session. In some variations, a method for acquiring positron emission data during a radiation therapy session comprises suspending communication between the PET detectors and a signal processor of a controller for a predetermined period of time after a radiation pulse has been emitted by the linac.
FILED Friday, May 29, 2020
APPL NO 16/887896
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 1/172 (20130101)
G01T 1/208 (20130101)
G01T 1/2023 (20130101)
G01T 1/2985 (20130101) Original (OR) Class
G01T 7/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287633 Liu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Congressionally Directed Medical Research Programs (CDMRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Jonathan T. C. Liu (Seattle, Washington);  Lindsey A. Barner (Seattle, Washington);  Adam K. Glaser (Seattle, Washington)
ABSTRACT Apparatuses, systems, and methods for solid immersion meniscus lenses (SIMlenses). An optical system may include a sample holder with a first side which supports a sample, and a second side opposite the first side. The second side of the sample holder may be in contact with an immersion fluid. Light passing between the sample and an objective lens may pass through the sample holder, immersion fluid, and a SIMlens positioned between the immersion fluid and objective. The SIMlens may have a first curved surface and a second curved surface, each of which may be shaped to match a wavefront of the light as it passes through the SIMlens. The immersion fluid, SIMlens, and environment containing the objective may all have different refractive indices.
FILED Wednesday, June 23, 2021
APPL NO 17/356135
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/26 (20130101)
G02B 21/0032 (20130101)
G02B 21/33 (20130101) Original (OR) Class
G02B 21/248 (20130101)
G02B 21/367 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11288846 Treilhard et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) KONINKLIJKE PHILIPS N.V. (Eindhoven, Netherlands);  Yale University (New Haven, Connecticut)
ASSIGNEE(S) KONINKLIJKE PHILIPS N.V. (Eindhoven, Netherlands);  YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S) John Treilhard (New Haven, Connecticut);  Ming De Lin (New Haven, Connecticut);  Jean-François Geschwind (Eindhoven, Netherlands);  James Duncan (New Haven, Connecticut);  Susanne Smolka (New Haven, Connecticut)
ABSTRACT In an image guidance method, a stream of cone-beam computed tomography (CBCT) images of an anatomical organ is acquired using a CBCT imaging device (34). For each CBCT image (44), the surface of the organ in the CBCT image is segmented to generate a segmented surface (70) of the anatomical organ in the CBCT image. Occluded shape reconstruction (66) using a statistical shape prior (68) may be used to reconstruct a missing or occluded surface portion. A pre-operative medical image (12) of the anatomical organ and the CBCT image are spatially registered by warping one of the images to the other of the images using point set registration of a segmented surface (30) of the organ in the preoperative medical image and the segmented surface of the organ in the CBCT image. A fused image (82) is displayed that combines the warped image and the other image.
FILED Thursday, September 28, 2017
APPL NO 16/333612
ART UNIT 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/12 (20170101)
G06T 7/0014 (20130101)
G06T 7/0016 (20130101)
G06T 7/143 (20170101)
G06T 7/344 (20170101)
G06T 11/003 (20130101) Original (OR) Class
G06T 2200/24 (20130101)
G06T 2207/10081 (20130101)
G06T 2207/10088 (20130101)
G06T 2207/10121 (20130101)
G06T 2207/20076 (20130101)
G06T 2207/20221 (20130101)
G06T 2207/30056 (20130101)
G06T 2207/30096 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11289301 Zhang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Tiezhi Zhang (St. Louis, Missouri);  Praneeth Kandlakunta (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Tiezhi Zhang (St. Louis, Missouri);  Praneeth Kandlakunta (St. Louis, Missouri)
ABSTRACT A multi-pixel x-ray source is provided. The x-ray source includes a plurality of transmission target assemblies. The transmission target assembly includes a tungsten target and a diamond substrate. The substrate includes a first transmission surface and a second transmission surface opposite first transmission surface. The substrate further includes a first side surface and a second side surface disposed between the first and second transmission surfaces. The target covers the first transmission surface of the substrate. The transmission target assembly further includes a base. The base surrounds the first and second side surfaces of substrate, exposing a collimator surface of the second transmission surface and the target. The transmission target assembly is configured to transmit x-ray generated by the target through the target and the substrate.
FILED Friday, November 06, 2020
APPL NO 17/091744
ART UNIT 2884 — Optics
CURRENT CPC
Electric Digital Data Processing
G06F 30/20 (20200101)

Electric Discharge Tubes or Discharge Lamps
H01J 35/12 (20130101)
H01J 35/116 (20190501) Original (OR) Class
H01J 2235/081 (20130101)
H01J 2235/083 (20130101)

X-ray Technique
H05G 1/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11289879 Yun
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
INVENTOR(S) Seok Hyun Yun (Belmont, Massachusetts)
ABSTRACT Disclosed are photonic particles and methods of using particles in biological samples. The particles are configured to emit laser light when energetically stimulated by, e.g., a pump source. The particles may include a gain medium with inorganic materials, an optical cavity with high refractive index, and a coating with organic materials. The particles may be smaller than 3 microns along their longest axes. The particles may attach to each other to form, e.g., doublets and triplets. The particles may be injection-locked by coupling an injection beam into a particle while pumping so that an injection seed is amplified to develop into laser oscillation. A microscopy system may include a pump source, beam scanner, spectrometer with resolution of less than 1 nanometer and acquisition rate of more than 1 kilohertz, and spectral analyzer configured to distinguish spectral peaks of laser output from broadband background.
FILED Monday, June 08, 2020
APPL NO 16/895914
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 2003/2826 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/648 (20130101)
G01N 2015/1006 (20130101)
G01N 2021/6439 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/091 (20130101)
H01S 3/169 (20130101)
H01S 3/213 (20130101)
H01S 3/0604 (20130101)
H01S 5/36 (20130101)
H01S 5/40 (20130101)
H01S 5/041 (20130101)
H01S 5/1025 (20130101)
H01S 5/1067 (20130101) Original (OR) Class
H01S 5/1075 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11284851 Madabhushi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Anant Madabhushi (Shaker Heights, Ohio);  Thomas Atta-Fosu (Cleveland Heights, Ohio);  Soumya Ghose (Niskayuna, New York)
ABSTRACT Embodiments access a set of radiological images acquired from a population of subjects, where a member of the set of radiological images includes a left atrium (LA) region; construct a statistical shape differential atlas from the images; generate a template LA model from the statistical shape differential atlas, where the template LA model includes a site of interest (SOI); acquire a pre-ablation radiological image of a region of tissue in a patient demonstrating atrial fibrillation (AF) pathology; generate a patient LA model from the pre-ablation image; compute a deformation field that registers the SOI to the patient LA model using deformable registration; compute a patient feature vector based on the deformation field; generate an AF probability score for the patient based on the feature vector; generate a classification of the patient based, at least in part, on the AF probability score; and display the classification or the AF probability score.
FILED Friday, March 22, 2019
APPL NO 16/361421
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/361 (20210101)
A61B 6/032 (20130101)
A61B 6/54 (20130101)
A61B 6/463 (20130101)
A61B 6/469 (20130101)
A61B 6/503 (20130101) Original (OR) Class
A61B 6/5217 (20130101)
A61B 2018/00351 (20130101)
A61B 2018/00577 (20130101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)

Image Data Processing or Generation, in General
G06T 2207/30048 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 10/60 (20180101)
G16H 30/40 (20180101)
G16H 50/20 (20180101)
G16H 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285046 Harrand et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
APPLICANT(S) CFD Research Corporation (Huntsville, Alabama)
ASSIGNEE(S) CFD Research Corporation (Huntsville, Alabama)
INVENTOR(S) Vincent Johannes Harrand (Huntsville, Alabama);  David Keith Sedberry, Jr. (Huntsville, Alabama);  Phillip Edward Whitley (Miami, Florida);  Xiangguang Gary Tan (Alexandria, Virginia);  Andrzej Przekwas (Huntsville, Alabama)
ABSTRACT A passive non-linear earplug can include: a tapered body having a channel extending from a wider distal end to a narrower proximal end, the tapered body having shape memory and size adapted for being received into an ear canal of a human subject; and a disk attached to the wider distal end of the tapered body, the disk having one or more holes aligned with the channel. A structural tube can be located in the channel. A handle can be attached to the tapered body and/or disk. An annular member can be coupled to the disk opposite of the tapered body, the annular member having an aperture that at least partially aligns with the channel. A tube member can be coupled to the disk opposite of the tapered body. The earplug can attenuate loud sounds while allowing normal sounds to be heard, which provides for the non-linearity.
FILED Wednesday, September 20, 2017
APPL NO 15/710646
ART UNIT 3786 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 11/08 (20130101) Original (OR) Class
A61F 2011/085 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285204 Dutta et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Agency for International Development (USAID)
Malaria Vaccine Development Program (MVDP)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Army (Fort Detrick, Maryland)
ASSIGNEE(S) THE GOVERNMENT OF THE UNITED STATES, AS REPRESEN (Fort Detrick, Maryland)
INVENTOR(S) Sheetij Dutta (Silver Spring, Maryland);  Adrian Batchelor (Baltimore, Maryland);  Farhat Khan (Columbia, Maryland);  Mark Langowski (Vienna, Virginia)
ABSTRACT The disclosure generally provides recombinant proteins comprising Tobamovirus capsid proteins and an immunogenic epitope of an antigen of interest. The recombinant protein can be used to assemble an array comprising a plurality of associated recombinant proteins that can enhance the immunogenicity of the epitope and induce and/or enhance an immune response to the antigen. The disclosure also provides compositions, such as vaccines, that include the recombinant protein as well as methods for inducing and/or enhancing an immune response in a mammal.
FILED Friday, September 21, 2018
APPL NO 16/649567
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101) Original (OR) Class
A61K 39/015 (20130101)
A61K 2039/64 (20130101)
A61K 2039/5258 (20130101)
A61K 2039/6075 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285319 Hubbard et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Ryan J. Hubbard (Woodland Hills, California);  Praveen K. Pilly (West Hills, California)
ABSTRACT A neuro-stimulation system comprising a user interface arranged for providing a user with a series of sensory stimuli, and for selecting, in response to a user input a group of selected sensory stimuli out of said series of sensory stimuli; a non-invasive brain stimulator arranged for stimulating the brain of the user with a different, unique, associated brain stimulus each time the user interface selects one stimulus of said group of selected sensory stimuli; and a controller arranged for detecting slow-wave sleep of the user and for causing the stimulator to stimulate the brain of the user with the brain stimuli associated with said group of selected sensory stimuli during the slow-wave sleep of the user.
FILED Thursday, April 04, 2019
APPL NO 16/375593
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/024 (20130101)
A61B 5/0205 (20130101)
A61B 5/369 (20210101)
A61B 5/0816 (20130101)
A61B 5/4812 (20130101)
A61B 5/6803 (20130101)
A61B 5/7475 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0456 (20130101)
A61N 1/36025 (20130101) Original (OR) Class
A61N 1/36031 (20170801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285320 Choe et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Office (CCDC ARO)
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Jaehoon Choe (Agoura Hills, California);  Praveen K. Pilly (West Hills, California)
ABSTRACT A neuro-stimulation system having: a controller; a user interface arranged for, under control of the controller, providing a user with a series of information elements to be learned by the user; a non-invasive brain stimulator arranged for, under the control of the controller, tagging each information element of said series of information elements by stimulating a brain of the user with a different, unique, associated brain stimulus when the user is provided said information element by said user interface; and a non-invasive brain sensor arranged for sending to the controller data indicating a slow-wave sleep period of the user; wherein the controller is further arranged for cueing each information element of said series of information elements by causing the stimulator to stimulate the brain of the user with the brain stimuli associated with said series of information elements during said slow-wave sleep period of the user.
FILED Thursday, April 04, 2019
APPL NO 16/375598
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/291 (20210101)
A61B 5/4809 (20130101)
A61B 5/6814 (20130101)
A61B 5/7475 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0456 (20130101)
A61N 1/3603 (20170801) Original (OR) Class

Electric Digital Data Processing
G06F 9/542 (20130101)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 19/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285456 Siu
FUNDED BY
Department of Homeland Security (DHS)
Countering Weapons of Mass Destruction Office (CWMD)
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Joint Program Executive Office for Chemical, Biological, Radiological and Nuclear Defense (JPEO-CBRND)
APPLICANT(S) Numat Technologies Inc. (Skokie, Illinois)
ASSIGNEE(S) NuMat Technologies, Inc. (Skokie, Illinois)
INVENTOR(S) Paul Wai-Man Siu (Chicago, Illinois)
ABSTRACT This invention relates to a Cu-BTC MOF which is water stable. The Cu-BTC MOF has open coordination sites and has been post synthesis modified by partially occupying the open sites with a ligand such as acetonitrile (CH3CN). The resultant MOF retains at least 40% of its as synthesized surface area after exposure to liquid water at 60° C. for 6 hours. This is an unexpected result versus the MOF which has not been post treated with ligands such as acetonitrile. This MOF can be used to abate contaminants such as ammonia in gas streams and especially air streams.
FILED Friday, August 14, 2020
APPL NO 16/993886
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/58 (20130101)
B01D 53/82 (20130101)
B01D 53/8634 (20130101)
B01D 2253/204 (20130101)
B01D 2255/705 (20130101)
B01D 2255/9207 (20130101)
B01D 2257/406 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/226 (20130101) Original (OR) Class
B01J 20/3085 (20130101)
B01J 20/28016 (20130101)
B01J 20/28019 (20130101)
B01J 20/28038 (20130101)
B01J 20/28045 (20130101)
B01J 20/28066 (20130101)
B01J 20/28073 (20130101)
B01J 31/1691 (20130101)
B01J 35/04 (20130101)
B01J 35/08 (20130101)
B01J 35/026 (20130101)
B01J 35/1028 (20130101)
B01J 37/04 (20130101)
B01J 37/10 (20130101)
B01J 2231/005 (20130101)
B01J 2531/16 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 1/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285572 Tindal
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Mitchell Tindal (Hartland, Wisconsin)
ABSTRACT A tripod jack cylinder removal tool including a lifting eyebolt attached through an up flange and further through and up flange aperture to a lock nut. The flange is secured to a pipe at a pipe top end, the pipe further having a bottom end wherein a down flange having a down flange aperture is attached to the pipe and a bolt having threads protrudes through a down flange aperture.
FILED Sunday, May 23, 2021
APPL NO 17/327738
ART UNIT 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools
B23P 19/04 (20130101) Original (OR) Class

Hoisting, Lifting, Hauling or Pushing, Not Otherwise Provided For, e.g Devices Which Apply a Lifting or Pushing Force Directly to the Surface of a Load
B66F 13/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285616 Penning et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Oklahoma City Air Logistics Complex (OC-ALC)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Teradyne, Inc. (North Reading, Massachusetts)
ASSIGNEE(S) Teradyne, Inc. (North Reading, Massachusetts)
INVENTOR(S) Ryan S. Penning (Madison, Wisconsin);  Ralph F. Polimeni, Jr. (Reno, Nevada);  Brett L. Limone (Danvers, Massachusetts);  James D. English (Alva, Florida)
ABSTRACT The specification and drawings present a robotic coating application system and a method for coating at least one part with a robotic coating application system. The robotic coating application system may comprise an enclosure configured to receive at least one part. The robotic coating application system may further comprise at least one robot configured to operate at least partially within the enclosure. The robotic coating application system may also comprise a graphical user interface to display a model of the at least one part and allow a user to select a portion or subportion of the model for application of a coating. The coating may be automatically applied to the at least one part based upon, at least in part, the user-selected portion or subportion.
FILED Tuesday, September 11, 2018
APPL NO 16/127960
ART UNIT 1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Spraying Apparatus; Atomising Apparatus; Nozzles
B05B 13/0431 (20130101)

Apparatus for Applying Fluent Materials to Surfaces, in General
B05C 5/0212 (20130101)
B05C 5/0216 (20130101)
B05C 9/10 (20130101)
B05C 13/02 (20130101)
B05C 15/00 (20130101)

Manipulators; Chambers Provided With Manipulation Devices
B25J 9/0081 (20130101)
B25J 9/163 (20130101)
B25J 11/0075 (20130101) Original (OR) Class
B25J 13/06 (20130101)
B25J 13/081 (20130101)
B25J 15/0066 (20130101)
B25J 19/022 (20130101)
B25J 19/023 (20130101)

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/042 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286269 Kerr et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as Represented by the Secretary of the Navy (Indian Head, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Andrew T. Kerr (Alexandria, Virginia);  Colt T. Hendley, IV (Lanham, Maryland);  Owen T. O'Sullivan (Alexandria, Virginia)
ABSTRACT Methods for synthesizing in situ two energetic compounds. A first energetic compound being characterized by a first local structure that features metal centers bound by 1-tetrazole, 4-cyanobenzene and azide molecules, while a second energetic compound is characterized by a second local structure that features metal centers bound by 1-methyltetrazole and azide molecules. Both energetic compounds may further be characterized as crystalline coordination polymers (CPs).
FILED Thursday, August 27, 2020
APPL NO 16/873954
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 1/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286391 Champagne, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts);  U.S. Army Research Laboratory (Adelphi, Maryland)
ASSIGNEE(S) THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts);  U.S. ARMY RESEARCH LABORATORY (Adelphi, Maryland)
INVENTOR(S) Victor Kenneth Champagne, Jr. (Dudley, Massachusetts);  Jessica Deborah Schiffman (Amherst, Massachusetts);  John Klier (Leverett, Massachusetts);  Guozhen Yang (Amherst, Massachusetts);  Mengfei Huang (Amherst, Massachusetts)
ABSTRACT In an embodiment, a composition comprises a plurality of reactive particles; wherein at least a first portion of the reactive particles comprises a first reactive monomer located in a first matrix polymer; wherein the first reactive monomer comprises a self-reactive monomer or wherein the first reactive monomer can polymerize with a second reactive monomer located in a second matrix polymer of a second portion of the reactive particles to form a coating polymer. In another embodiment, a method of making the plurality of reactive particles, comprises polymerizing a first matrix monomer in the presence of the first reactive monomer; or polymerizing the first matrix monomer to form a plurality of particles and swelling the plurality of particles with the first reactive monomer. In another embodiment, a method comprises cold spraying the plurality of reactive particles.
FILED Monday, April 09, 2018
APPL NO 16/497880
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/12 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 4/06 (20130101) Original (OR) Class
C09D 5/03 (20130101)
C09D 7/70 (20180101)
C09D 133/12 (20130101)
C09D 163/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286492 Thess et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) CureVac AG (Tübingen, Germany)
ASSIGNEE(S) CureVac AG (Tübingen, Germany)
INVENTOR(S) Andreas Thess (Kusterdingen, Germany);  Thomas Schlake (Gundelfingen, Germany);  Stefanie Grund (Stuttgart, Germany)
ABSTRACT The invention relates to an artificial nucleic acid molecule comprising an open reading frame and a 3′-UTR comprising at least one poly(A) sequence or a polyadenylation signal. The invention further relates to a vector comprising the artificial nucleic acid molecule comprising an open reading frame and a 3′-UTR comprising at least one poly(A) sequence or a polyadenylation signal, to a cell comprising the artificial nucleic acid molecule or the vector, to a pharmaceutical composition comprising the artificial nucleic acid molecule or the vector and to a kit comprising the artificial nucleic acid molecule, the vector and/or the pharmaceutical composition. The invention also relates to a method for increasing protein production from an artificial nucleic acid molecule and to the use of a 3′-UTR for a method for increasing protein production from an artificial nucleic acid molecule. Moreover, the invention concerns the use of the artificial nucleic acid molecule, the vector, the kit or the pharmaceutical composition as a medicament, as a vaccine or in gene therapy.
FILED Friday, August 20, 2021
APPL NO 17/408332
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/145 (20130101)
A61K 39/205 (20130101)
A61K 48/00 (20130101)
A61K 2039/53 (20130101)
A61K 2039/54 (20130101)
A61K 2039/575 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/67 (20130101) Original (OR) Class
C12N 15/68 (20130101)
C12N 15/85 (20130101)
C12N 2760/16134 (20130101)
C12N 2760/16171 (20130101)
C12N 2760/20134 (20130101)
C12N 2760/20171 (20130101)
C12N 2830/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286517 Kishi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Jocelyn Yoshiko Kishi (Boston, Massachusetts);  Thomas E. Schaus (Arlington, Massachusetts);  Peng Yin (Brookline, Massachusetts);  Feng Xuan (Boston, Massachusetts);  Nikhil Gopalkrishnan (Jamaica Plain, Massachusetts);  Sungwook Woo (Chestnut Hill, Massachusetts)
ABSTRACT The present disclosure provides, in some aspects, nucleic acid-based molecular tools that enable the recording of molecular structure and soluble signals as well as the programmed assembly of molecular structures.
FILED Thursday, February 16, 2017
APPL NO 15/999245
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/64 (20130101)
C12N 15/113 (20130101)
C12N 2310/122 (20130101)
C12N 2310/127 (20130101)
C12N 2330/50 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)
C12Q 1/6806 (20130101)
C12Q 1/6809 (20130101)
C12Q 1/6811 (20130101) Original (OR) Class
C12Q 1/6825 (20130101)
C12Q 1/6825 (20130101)
C12Q 1/6853 (20130101)
C12Q 1/6853 (20130101)
C12Q 2525/155 (20130101)
C12Q 2525/155 (20130101)
C12Q 2525/186 (20130101)
C12Q 2525/186 (20130101)
C12Q 2525/204 (20130101)
C12Q 2525/204 (20130101)
C12Q 2525/301 (20130101)
C12Q 2525/301 (20130101)
C12Q 2525/301 (20130101)
C12Q 2531/101 (20130101)
C12Q 2531/101 (20130101)
C12Q 2531/119 (20130101)
C12Q 2531/119 (20130101)
C12Q 2531/119 (20130101)
C12Q 2533/101 (20130101)
C12Q 2533/101 (20130101)
C12Q 2537/16 (20130101)
C12Q 2537/16 (20130101)
C12Q 2537/149 (20130101)
C12Q 2537/149 (20130101)
C12Q 2537/157 (20130101)
C12Q 2537/157 (20130101)
C12Q 2537/163 (20130101)
C12Q 2537/163 (20130101)
C12Q 2537/1373 (20130101)
C12Q 2537/1373 (20130101)
C12Q 2537/1376 (20130101)
C12Q 2537/1376 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286525 Tsalik et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Veterans Affairs (DVA)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina);  United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Ephraim L. Tsalik (Cary, North Carolina);  Geoffrey S. Ginsburg (Durham, North Carolina);  Christopher W. Woods (Durham, North Carolina);  Ricardo Henao Giraldo (Durham, North Carolina);  Rachel A. Myers (Raleigh, North Carolina)
ABSTRACT The present disclosure provides methods for determining whether a subject has sepsis, or is at risk of developing sepsis, and methods of treating the subject based on the determination. Also provided are methods for determining an increased risk of mortality in a subject with sepsis or suspected of having sepsis, and methods of treating the subject based on the determination. Systems useful for the same are also provided.
FILED Tuesday, January 16, 2018
APPL NO 16/478202
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6876 (20130101) Original (OR) Class
C12Q 2600/118 (20130101)
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286711 Judson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) United States of America as Represented by The Secretary of The Army (Alexandria, Virginia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia)
INVENTOR(S) John S Judson (Vicksburg, Mississippi);  David V Senior (Vicksburg, Mississippi);  Craig R Ackerman (Gainesville, Virginia);  Daniel Duke (Washington, District of Columbia)
ABSTRACT Blast, ballistic, and entry resistant compression frame systems include a plurality of bolts, an exterior frame assembly having a peripheral flange and a plurality of sleeves that receive the bolts, an interior frame assembly having a peripheral flange and a plurality of apertures that receive the bolts therethrough, an exterior gasket between the peripheral flange of the exterior frame assembly and an exterior surface of the wall of the building, and an interior gasket between the peripheral flange of the interior frame assembly and an interior surface of the wall of the building. The exterior frame assembly peripheral flange and the interior frame assembly peripheral flange apply a compression force to the wall when the bolts are torque tightened into the threaded sleeves. Methods of installation in a wall of a building are also provided.
FILED Monday, September 30, 2019
APPL NO 16/589063
ART UNIT 3635 — Static Structures, Supports and Furniture
CURRENT CPC
Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates
E06B 5/106 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286789 Ghigliotty et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S) Raytheon Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Jaime G Ghigliotty (Cabo Rojo, Puerto Rico);  David J Candelori (Glastonbury, Connecticut);  San Quach (Southington, Connecticut)
ABSTRACT An airfoil for a gas turbine engine is disclosed. In various embodiments, the airfoil includes a cooling passage; an outer wall separating a core flow path from the cooling passage; a diffuser in fluid communication with the cooling passage and opening into the core flow path, the diffuser being characterized by a linear ridge on a downstream end of the diffuser; and a thermal barrier coating covering the outer wall and the linear ridge.
FILED Thursday, July 02, 2020
APPL NO 16/920014
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/186 (20130101) Original (OR) Class
F01D 25/12 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2230/90 (20130101)
F05D 2240/12 (20130101)
F05D 2240/14 (20130101)
F05D 2240/35 (20130101)
F05D 2250/12 (20130101)
F05D 2260/202 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286790 Quach et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) Raytheon Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S) San Quach (East Hartford, Connecticut);  Christopher King (Bristol, Connecticut);  Tracy A. Propheter-Hinckley (Manchester, Connecticut)
ABSTRACT A gas turbine engine component includes a wall that has an inner surface and an outer surface. An inlet is defined by the inner surface. At least one non-rectangular slot is defined by the outer surface and includes at least one protrusion extending into the slot. A slot passage fluidly connects the inlet to the at least one non-rectangular slot. The slot passage comprises an inlet portion that extends through the wall from the inlet to an intermediate portion. An outlet portion extends through the wall from the intermediate portion to the at least one non-rectangular slot.
FILED Wednesday, September 02, 2020
APPL NO 17/009936
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/186 (20130101) Original (OR) Class
F01D 9/041 (20130101)
F01D 11/08 (20130101)
F01D 25/12 (20130101)

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/18 (20130101)

Non-positive-displacement Pumps
F04D 29/324 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2240/12 (20130101)
F05D 2240/30 (20130101)
F05D 2240/35 (20130101)
F05D 2250/13 (20130101)
F05D 2250/182 (20130101)
F05D 2250/183 (20130101)
F05D 2250/184 (20130101)
F05D 2250/185 (20130101)
F05D 2260/202 (20130101)
F05D 2260/204 (20130101)

Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers
F23R 3/002 (20130101)
F23R 2900/03042 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286805 Brostmeyer et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Florida Turbine Technologies, Inc. (Jupiter, Florida)
ASSIGNEE(S) Florida Turbine Technologies, Inc. (Jupiter, Florida)
INVENTOR(S) Joseph D. Brostmeyer (Jupiter, Florida);  Robert A. Ress, Jr. (Carmel, Indiana);  Tyler W. Sloss (Chapel Hill, North Carolina);  Barry J. Brown (Jupiter, Florida)
ABSTRACT A geared turbofan engine with at least one compression stage and at least one turbine stage on a high speed shaft, the high speed shaft coupled through a speed reduction gear box to a low speed shaft with a fan and a starter/generator. The low speed shaft is collinear with the high speed shaft but does not rotate within the high speed shaft. The speed reduction gear box is positioned between and mechanically couples the high speed shaft and the low speed shaft, which allows the fan and the integrated starter/generator on the low speed shaft to operate at a lower speed than the high speed shaft.
FILED Monday, June 22, 2020
APPL NO 16/908566
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 15/10 (20130101)
F01D 15/12 (20130101) Original (OR) Class
F01D 25/16 (20130101)

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/06 (20130101)
F02C 7/32 (20130101)
F02C 7/36 (20130101)
F02C 7/275 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286853 Cerny et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Matthew Robert Cerny (West Chester, Ohio);  Christopher James Kroger (Cincinnati, Ohio);  Brandon Wayne Miller (Cincinnati, Ohio)
ABSTRACT A thermal management system for a gas turbine engine and/or an aircraft is provided including a thermal transport bus having a heat exchange fluid flowing therethrough. The thermal management system also includes a plurality of heat source exchangers and at least one heat sink exchanger. The plurality of heat source exchangers and the at least one heat sink exchanger are in thermal communication with the heat exchange fluid in the thermal transport bus. The plurality of heat source exchangers are arranged along the thermal transport bus and configured to transfer heat from one or more accessory systems to the heat exchange fluid, and the at least one heat sink exchanger is located downstream of the plurality of heat source exchangers and configured to remove heat from the heat exchange fluid.
FILED Monday, October 22, 2018
APPL NO 16/167408
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/06 (20130101) Original (OR) Class
F02C 7/14 (20130101)
F02C 7/16 (20130101)
F02C 7/185 (20130101)
F02C 7/224 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2260/213 (20130101)

Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems
F25B 1/00 (20130101)
F25B 41/31 (20210101)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 15/00 (20130101)
F28D 2021/0021 (20130101)
F28D 2021/0026 (20130101)

Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 27/02 (20130101)
F28F 2250/08 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286881 Boyd et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Aviation Applied Technology Directorate (AATD)
U.S. Army Contracting Command (ACC)
Redstone Arsenal (REDSTONE)
APPLICANT(S) Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana)
ASSIGNEE(S) Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana)
INVENTOR(S) Douglas Boyd (Indianapolis, Indiana);  Douglas D. Dierksmeier (Franklin, Indiana);  Douglas J. Snyder (Carmel, Indiana);  Graham Burkholder (Avon, Indiana);  William B. Bryan (Indianapolis, Indiana)
ABSTRACT A gas turbine engine system includes a gas turbine engine having a fan bypass duct, a heat exchanger system, and a flow transfer unit configured to selectively allow or preclude flow between the fan bypass duct and the heat exchanger system. A controller is coupled to and configured to vary the state of one or more of a fan exit nozzle, a heat exchanger exit nozzle, and a flow control valve controlling flow between the fan bypass duct and the heat exchanger system.
FILED Wednesday, October 16, 2019
APPL NO 16/654706
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 3/04 (20130101)
F02C 6/08 (20130101)
F02C 7/18 (20130101)
F02C 7/185 (20130101)
F02C 9/18 (20130101)

Jet-propulsion Plants
F02K 1/74 (20130101) Original (OR) Class
F02K 3/06 (20130101)
F02K 3/115 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/36 (20130101)
F05D 2220/323 (20130101)
F05D 2240/35 (20130101)
F05D 2260/213 (20130101)
F05D 2260/606 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287086 Mitchell et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Wavefront Research, Inc. (Bethlehem, Pennsylvania)
ASSIGNEE(S) Wavefront Research, Inc. (Northhampton, Pennsylvania)
INVENTOR(S) Thomas A. Mitchell (Bethlehem, Pennsylvania);  Jonas D. Corl (Bethlehem, Pennsylvania)
ABSTRACT A system including an optical system having at least one refractive or reflective element, the optical system configured to substantially receive electromagnetic radiation emanating from a source, the optical system being located within a Dewar, a support structure, support structure being mechanically disposed between the optical system and a surface of the Dewar, the support structure having substantially low thermal conductance, a cold source; the cold source being located within the Dewar, a thermal link, the thermal link being mechanically disposed between the optical system and the cold source, the thermal link being substantially flexible and having substantially high thermal conductance.
FILED Friday, April 20, 2018
APPL NO 15/958190
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases
F17C 3/085 (20130101) Original (OR) Class
F17C 2250/07 (20130101)
F17C 2250/038 (20130101)
F17C 2250/0478 (20130101)
F17C 2250/0491 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287117 Ross et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
APPLICANT(S) First-Light USA, LLC (Seymour, Illinois)
ASSIGNEE(S) First-Light USA, LLC (Seymour, Illinois)
INVENTOR(S) Jeremy B. Ross (Monticello, Illinois);  Blake S. Good (Urbana, Illinois);  Jacob A. Flagle (New Palestine, Indiana)
ABSTRACT A frame having a clip for securing the frame to an article of clothing or other object. The frame includes a mount for receiving a removable module and a rotatably attached clip. The clip includes an opening for accommodating sewing ribs between portions of a webbing and a gate (which may be a locking wire) moveable between an open position and a closed position at one end of the opening. In the open position, the locking wire removably engages one of a pair of elongated members defining the opening, e.g., by removably engaging that elongated member at a recess in an outside edge thereof, and does not obstruct the opening. When in the closed position, the locking wire removably engages the other of the elongated members, for example by removably engaging that other elongated member at a recess in its outside edge, and obstructs the longitudinal opening.
FILED Monday, August 03, 2020
APPL NO 16/983252
ART UNIT 2875 — Optics
CURRENT CPC
Lighting Devices or Systems Thereof, Being Portable or Specially Adapted for Transportation
F21L 4/027 (20130101)
F21L 4/045 (20130101)

Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for
F21V 21/145 (20130101)
F21V 21/0885 (20130101) Original (OR) Class

Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to Uses or Applications of Lighting Devices or Systems
F21W 2111/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287229 Panchal et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Viral Panchal (Parlin, New Jersey);  Chong Peng (Mason, Ohio);  Dale Conti (Andover, New Jersey);  Ming-Wan Young (Basking Ridge, New Jersey);  Tianyi Huang (Tenafly, New Jersey)
ABSTRACT The present invention is directed to a process for making combustible foam celluloid munition parts having high aspect ratios, different densities or having an insert embedded into the foam celluloid munition part. The process for making such foam celluloid munition part requires pre-soaking dry particles of celluloid, placing the celluloid particles into a munition part mold, exposing the celluloid particles to high heat and pressure until the celluloid particles expand and fuse into the shape of the mold. Varying the density or the size of the celluloid particles used in the process produces munition parts having different densities. In addition, the placement of inserts into the particles prior to exposure to high heat and pressure produces munition parts having inserts that are useful for identification and tracking of such parts.
FILED Wednesday, January 29, 2020
APPL NO 16/775307
ART UNIT 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 44/1266 (20130101)
B29C 44/3461 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2001/18 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/7772 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 9/122 (20130101)
C08J 2203/06 (20130101)
C08J 2301/08 (20130101)

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 5/188 (20130101) Original (OR) Class
F42B 5/192 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287234 Hardt et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Lee R. Hardt (Ridgecrest, California);  Donald L. Burnett (Spearfish, South Dakota);  Josiah S. Garfield (Ridgecrest, California);  Robert A. Koontz (Anchorage, Alaska);  Eric K. Wooding (Ridgecrest, California);  Que T. BuiDang (Ridgecrest, California)
ABSTRACT The disclosed embodiments are directed to enhancing insensitive munitions performance. Some of the embodiments employ an outgassing pad having unique geometrical configurations, compositions, and positioning. Other embodiments rely on using thermally-releasable components to foster billet expulsion. Additional embodiments combine both aspects into entire cook-off mitigation systems for insensitive munitions improvements.
FILED Thursday, May 07, 2020
APPL NO 16/868756
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance
F41A 17/16 (20130101)

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 12/20 (20130101)
F42B 12/207 (20130101) Original (OR) Class
F42B 39/14 (20130101)
F42B 39/20 (20130101)

Ammunition Fuzes; Arming or Safety Means Therefor
F42C 19/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287237 Pirozzi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) John Pirozzi (Holmdel, New Jersey);  Lloyd Khuc (Wharton, New Jersey);  Daniel Altamura (Budd Lake, New Jersey);  Lei Zheng (Morris Plains, New Jersey);  William Leach (Columbia, New Jersey)
ABSTRACT In a projectile launch environment, a fuzing safety device independently generates its own voltage upon setback which then is then used to arm the projectile. The arming is done independently of any on board battery rise time, and setback scenarios are detected free of false impacts such as dropping or jostling. The fuzing safety device includes a piezoelectric sensor for detecting motion in the projectile.
FILED Thursday, September 03, 2020
APPL NO 17/010974
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition Fuzes; Arming or Safety Means Therefor
F42C 15/24 (20130101) Original (OR) Class
F42C 15/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287238 Albrecht
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Nicholas H. Albrecht (Ridgecrest, California)
ABSTRACT The embodiments are directed to methods of initiating insensitive explosive formulations. The disclosed methods include positioning a donor explosive pellet adjacent to an insensitive acceptor explosive pellet having a plurality of relative percent theoretical maximum density (TMD) zones. The insensitive acceptor explosive pellet is adjacent to an insensitive explosive fill. Upon donor explosive pellet initiation, the donor explosive pellet provides a shock stimulus to the insensitive acceptor explosive pellet, which initiates the insensitive acceptor explosive pellet, causing a detonation wave to be driven through the plurality of relative percent TMD zones and into the insensitive explosive fill.
FILED Wednesday, December 02, 2020
APPL NO 17/109691
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition Fuzes; Arming or Safety Means Therefor
F42C 19/0815 (20130101) Original (OR) Class
F42C 19/0838 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287239 Polk et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Aberdeen Proving Ground (APG)
Combat Capabilities Development Command (CCDC)
Chemical Biological Center (CCDC CBC)
APPLICANT(S) Combat Capabilities Development Command, Chemical Biological Center (Apg, Maryland)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Amee L Polk (Havre de Grace, Maryland);  Joseph A Domanico (Bel Air, Maryland);  Michael F Kauzlarich (Edgewood, Maryland);  Nino L Bonavito (Perry Hall, Maryland);  Warren L Gardner (Bel Air, Maryland)
ABSTRACT A fast utility access device (FUAD) is provided that includes one or more casings, each of the one or more casings collectively defining a bore, and a core of a highly exothermic composition contained in the bore and surrounded by a thermally insulating inner liner, the highly exothermic composition ignitable to create a post-ignition temperature of between 500° C. and 4000° C. A method is also provided for breaching a target and includes contacting the inventive access device with a breaching target substrate, thermally coupling at least one reaction initiator to the highly exothermic composition, triggering the at least one reaction initiator thereby igniting the highly exothermic composition, and allowing the highly exothermic composition to achieve a post-ignition temperature sufficient to melt the breaching target substrate, forming a hole therethrough.
FILED Thursday, July 23, 2020
APPL NO 16/937113
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives
C06B 33/00 (20130101)

Blasting
F42D 1/043 (20130101) Original (OR) Class
F42D 3/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287244 Acker et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) BAE SYSTEMS INFORMATION AND ELECTRONIC SYSTEMS INTEGRATION INC. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Andrew N. Acker (Honolulu, Hawaii);  Michael J. DeWeert (Kaneohe, Hawaii)
ABSTRACT A shearography a system and method for regularizing phase resolved shearograms with an arctan regularization function to produce regularized phase resolved shearogram outputs is provided. The system and method of the present disclosure optimizes the processing of phase resolved shearography allowing interference fringe analysis techniques to be applied to the regularized phase resolved shearogram output results of the processing.
FILED Friday, May 17, 2019
APPL NO 16/414871
ART UNIT 2877 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 9/02098 (20130101)
G01B 11/162 (20130101) Original (OR) Class

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 9/0215 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287328 Soo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as Represented by the Secretary of the Navy (Indian Head, Maryland)
ASSIGNEE(S) The United States of America as represented by The Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Michael Soo (Alexandria, Virginia);  John-Mark Clemenson, Jr. (Arlington, Virginia);  Michael S. Kessler (LaPlata, Maryland);  Adam W. Sims (Marbury, Maryland);  Sam Goroshin (Montreal, Canada)
ABSTRACT A thermocouple (TC) protection gauge may guard TCs from flying debris and fragments in an explosive environment or demanding commercial environments. The gauge may contain multiple co-located TCs. By using the protection gauge, the survivability of the TCs is significantly increased and allows for a longer time frame of data collection. Temperature data is acquired from multiple TCs that are experiencing approximately the same gas temperature and gas velocity. The temperature data may be used to reconstruct the real gas temperature of a dynamic event. Each of the TCs has a different diameter and therefore has a different time resolved temperature trace. The individual temperature traces may be used to extrapolate the real gas temperature using, for example, a reconstruction algorithm.
FILED Thursday, August 27, 2020
APPL NO 16/873957
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 1/08 (20130101) Original (OR) Class
G01K 1/026 (20130101)
G01K 7/02 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 35/02 (20130101)
H01L 35/30 (20130101)
H01L 35/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287390 Letourneau et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Reservoir Labs, Inc. (New York, New York)
ASSIGNEE(S) Reservoir Labs, Inc. (New York, New York)
INVENTOR(S) Pierre-David Letourneau (Long Island, New York);  Mitchell Harris (New York, New York)
ABSTRACT A technique for measuring properties of a material includes measuring the electromagnetic radiation scattered by one or more scattering points associated with the material, and adjusting the radiation according to the respective sensitivities of the scattering points to changes in material properties at that scattering point for several pairs of radiation sources and receivers. The material properties are determined using the updated measurements and corresponding simulated measurements.
FILED Thursday, January 30, 2020
APPL NO 16/777189
ART UNIT 2867 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 22/00 (20130101) Original (OR) Class
G01N 22/02 (20130101)
G01N 23/00 (20130101)
G01N 23/20 (20130101)
G01N 27/04 (20130101)
G01N 27/22 (20130101)
G01N 27/72 (20130101)
G01N 27/221 (20130101)

Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 3/30 (20130101)

Image Data Processing or Generation, in General
G06T 11/003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287430 Delehanty et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) James B. Delehanty (Washington, District of Columbia);  Michael H. Stewart (Springfield, Virginia);  Okhil Nag (Alexandria, Virginia);  Jeffrey R. Deschamps (Laurel, Maryland);  Kimihiro Susumu (Alexandria, Virginia);  Eunkeu Oh (Alexandria, Virginia);  Lauren D. Field (College Park, Maryland);  Alexander L. Efros (Annandale, Virginia);  Alan L. Huston (Aldie, Virginia);  Igor L. Medintz (Springfield, Virginia);  Philip E. Dawson (San Diego, California)
ABSTRACT A construct for detecting cellular membrane potential includes a nanoparticle operable as an electron donor; a modular peptide attached to the nanoparticle, the peptide comprising a nanoparticle association domain, a motif configured to mediate peptide insertion into the plasma membrane, and at least one attachment point for an electron acceptor positioned at a controlled distance from the nanoparticle; and an electron acceptor. The nanoparticle can be a quantum dot and the electron acceptor can be C60 fullerene. Emission correlates with cellular membrane potential.
FILED Monday, June 08, 2020
APPL NO 16/894920
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 2319/035 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/588 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287508 Zalalutdinov et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Maxim K. Zalalutdinov (Silver Spring, Maryland);  Douglas M. Photiadis (Falls Church, Virginia);  Joseph A. Bucaro (Herndon, Virginia);  Brian H. Houston (Fairfax, Virginia)
ABSTRACT Systems and methods are provided for sensing acoustic signals using a floating base vector sensor. A vector sensor according to an embodiment of the present disclosure can be used to detect and characterize low frequency sound wave(s) in a viscous medium (e.g., air, water, etc.) by detecting a periodic motion of the media particles associated with the sound wave(s). The orientation of the particle velocity deduced from such measurements can provide information regarding the wave vector of the sound wave(s), can define the direction of arrival (DOA) for the acoustic signal, and can assist locating the source of the sound of interest.
FILED Thursday, May 03, 2018
APPL NO 15/970369
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume
G01F 1/28 (20130101)
G01F 1/704 (20130101)

Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves
G01H 9/00 (20130101)

Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 5/26 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 3/801 (20130101)
G01S 3/8034 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287522 Vazquez et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S) The Aerospace Corporation (El Segundo, California)
ASSIGNEE(S) THE AEROSPACE CORPORATION (El Segundo, California)
INVENTOR(S) George Vazquez (Woodland Park, Colorado);  Christopher Bass (Colorado Springs, Colorado)
ABSTRACT A single space platform with an optical telescope, a spectrometer, and/or a database of stored spectral information may be used to determine the range and/or velocity of natural or artificial resident space objects (RSOs). Relativistic Doppler shift measured from reflected solar photons and/or photons from other emitting source(s) provides information that the space platform can use to determine the relative velocity and the range rate. This information can then be used in combination with the right ascension and declination angles to perform differential correction and obtain an updated orbit.
FILED Tuesday, October 16, 2018
APPL NO 16/161232
ART UNIT 2863 — Printing/Measuring and Testing
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 5/16 (20130101)
G01S 7/40 (20130101)
G01S 11/12 (20130101)
G01S 13/32 (20130101)
G01S 13/583 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287550 Posey et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Pamela Posey (Carriere, Mississippi);  Richard Arthur Allard (Pass Christian, Mississippi);  Julia Crout (Slidell, Louisiana);  Gregg Arthur Jacobs (Slidell, Louisiana)
ABSTRACT Embodiments relate to leads and polynyas forecasting. Initially observed ice forecast data is obtained for a geographic area of interest, which is then used to generate an ice grid based on the observed ice data, where the ice grid includes grid cells that map polar regions. At this stage, daily opening rates are determined based on the ice grid, where each daily opening rate indicates an opening speed of a corresponding ice event, and daily convergence strain rates are determined based on the ice grid, where each daily convergence strain rate indicates a convergence of the corresponding ice event. For each day, a daily opening rate is weighted and then adjusting by a daily convergence strain rate. A forecasted opening rate on a target date is determined based on the weighted, adjusted daily opening rates. Predicted openings of the polar region can be rendered based on the forecasted opening rate.
FILED Monday, March 27, 2017
APPL NO 15/470373
ART UNIT 2862 — Printing/Measuring and Testing
CURRENT CPC
Meteorology
G01W 1/00 (20130101)
G01W 1/10 (20130101) Original (OR) Class
G01W 2203/00 (20130101)

Image Data Processing or Generation, in General
G06T 11/60 (20130101)

Technologies for Adaptation to Climate Change
Y02A 90/10 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287569 Soo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as Represented by the Secretary of the Navy (Indian Head, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Michael Soo (Alexandria, Virginia);  Meghan Bash (Springfield, Virginia)
ABSTRACT A high-speed imaging system for capturing images of flow created by initiation of energetic material includes a lens collector disposed in a protective shield. The protective shield helps protect the lens collector from damage due to the blast event. The lens connector is connected to an incoherent optical fiber bundle made of a bundle of coherent fiber bundles. The incoherent optical fiber bundle creates scrambled images that are relayed to a high-speed camera. A computer connected to the high-speed camera unscrambles the scrambled images to reproduce the images of the flow.
FILED Wednesday, February 17, 2021
APPL NO 17/300028
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/06 (20130101) Original (OR) Class

Pictorial Communication, e.g Television
H04N 5/22521 (20180801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287575 Williams et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) US Gov't as represented by Secretary of Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Jeremiah C Williams (Dayton, Ohio);  Hengky Chandrahalim (Beavercreek, Ohio)
ABSTRACT A method is provided for fabricating a passive optical sensor on a tip of an optical fiber. The method includes perpendicularly cleaving a tip of an optical fiber and mounting the tip of the optical fiber in a specimen holder of a photosensitive polymer three-dimensional micromachining machine. The method includes forming a three-dimensional microscopic optical structure within the photosensitive polymer that comprises a two cavity Fabry-Perot Interferometer (FPI) having a hinged optical layer that is pivotally coupled to a suspended structure. The method includes removing an uncured portion of the photosensitive polymer using a solvent. The method includes depositing a reflective layer on a mirror surface of the hinged optical layer. The method includes positioning the pivotally hinged optical layer to a closed position with the suspended structure, aligning the mirror surface with the cleaved tip of the optical fiber.
FILED Wednesday, April 21, 2021
APPL NO 17/236028
ART UNIT 2883 — Optics
CURRENT CPC
Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 7/065 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/02033 (20130101)
G02B 6/29358 (20130101)
G02B 6/29359 (20130101) Original (OR) Class
G02B 2006/12159 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287633 Liu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Congressionally Directed Medical Research Programs (CDMRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Jonathan T. C. Liu (Seattle, Washington);  Lindsey A. Barner (Seattle, Washington);  Adam K. Glaser (Seattle, Washington)
ABSTRACT Apparatuses, systems, and methods for solid immersion meniscus lenses (SIMlenses). An optical system may include a sample holder with a first side which supports a sample, and a second side opposite the first side. The second side of the sample holder may be in contact with an immersion fluid. Light passing between the sample and an objective lens may pass through the sample holder, immersion fluid, and a SIMlens positioned between the immersion fluid and objective. The SIMlens may have a first curved surface and a second curved surface, each of which may be shaped to match a wavefront of the light as it passes through the SIMlens. The immersion fluid, SIMlens, and environment containing the objective may all have different refractive indices.
FILED Wednesday, June 23, 2021
APPL NO 17/356135
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/26 (20130101)
G02B 21/0032 (20130101)
G02B 21/33 (20130101) Original (OR) Class
G02B 21/248 (20130101)
G02B 21/367 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287642 Valentine et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Jason G. Valentine (Nashville, Tennessee);  Cary L. Pint (Nashville, Tennessee);  Zachary J. Coppens (Nashville, Tennessee);  Adam P. Cohn (Nashville, Tennessee)
ABSTRACT A device according to one example of principles described herein may include a backplane, electrochemical actuator, and an optical resonator, wherein the electrochemical actuator is located between the backplane and optical resonator. Applied energy may be used to modify the volume of the electrochemical actuator material modifying the resonant/interferometric absorption, transmission, and reflection at visible and/or infrared frequencies.
FILED Wednesday, September 19, 2018
APPL NO 16/135697
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 26/001 (20130101) Original (OR) Class
G02B 26/085 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/21 (20130101)
G02F 1/0123 (20130101)
G02F 1/155 (20130101)
G02F 1/213 (20210101)
G02F 2001/1536 (20130101)
G02F 2201/083 (20130101)
G02F 2203/02 (20130101)
G02F 2203/15 (20130101)
G02F 2203/055 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287706 Idehenre et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Ighodalo U. Idehenre (Tipp City, Ohio);  Dean R. Evans (Beavercreek, Ohio)
ABSTRACT A transparent device for use in optical applications, and methods for using and manufacturing the device are disclosed. The device generally requires several layers, including (i) a first layer comprising a transparent conductive oxide (such as indium tin oxide (ITO)), (ii) a second layer comprising a transparent semiconductor (e.g., a pn-heterojunction or a pn-homojunction), the second layer having a surface facing the first layer, (iii) a third layer comprising a liquid crystal (such as E7), the third layer having a surface facing the second layer, and (iv) a fourth layer comprising either a second transparent conductive oxide or a second transparent semiconductor, the fourth layer having a surface facing the third layer. When light illuminates a surface of the transparent metal oxide pn-heterojunction or transparent metal oxide pn-homojunction, it induces photoconductivity, modifying the surface charges.
FILED Wednesday, December 16, 2020
APPL NO 17/123157
ART UNIT 2879 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/1354 (20130101) Original (OR) Class
G02F 1/1357 (20210101)
G02F 1/133784 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287819 Blankespoor et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Boston Dynamics, Inc. (Waltham, Massachusetts)
ASSIGNEE(S) Boston Dynamics, Inc. (Waltham, Massachusetts)
INVENTOR(S) Kevin Blankespoor (Arlington, Massachusetts);  Gabriel Nelson (Waltham, Massachusetts);  Neil Neville (Waltham, Massachusetts)
ABSTRACT A method for estimating a ground plane includes receiving a pose of a robotic device with respect to a gravity aligned reference frame, receiving one or more locations of one or more corresponding contact points between the robotic device and a ground surface, and determining a ground plane estimation of the ground surface based on the orientation of the robotic device with respect to the gravity aligned reference frame and the one or more locations of one or more corresponding contact points between the robotic device and the ground surface. The ground plane estimation includes a ground surface contour approximation. The method further includes determining a distance between a body of the robotic device and the determined ground plane estimation and causing adjustment of the pose of the robotic device with respect to the ground surface based on the determined distance and the determined ground plane estimation.
FILED Tuesday, October 08, 2019
APPL NO 16/596006
ART UNIT 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/0006 (20130101)
B25J 9/1615 (20130101)
B25J 9/1694 (20130101)
B25J 9/1697 (20130101)

Motor Vehicles; Trailers
B62D 57/032 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 1/0088 (20130101) Original (OR) Class
G05D 1/0891 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 901/01 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11288090 Cui et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Ang Cui (New York, New York);  Salvatore J. Stolfo (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Ang Cui (New York, New York);  Salvatore J. Stolfo (New York, New York)
ABSTRACT Methods, systems, and media for injecting code into embedded devices are provided. In accordance with some embodiments, methods for injecting code into embedded devices are provided, the methods comprising: embedding payload execution code into an embedded device; identifying program instructions in code of the embedded device into which jump instructions can be placed; inserting at least one jump instruction at an identified program instruction; allocating memory for storing an execution context of an injected payload; saving a context of the code of the embedded device to memory; loading and executing a payload context into a processor of the embedded device; determining when execution of the payload context is to be interrupted; and in response to determining that the execution of the payload context is to be interrupted, saving the payload context, restoring the context of the code of the embedded device, and continuing execution of the code of the embedded device.
FILED Monday, August 20, 2018
APPL NO 16/105557
ART UNIT 2182 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 8/656 (20180201)
G06F 9/48 (20130101)
G06F 9/461 (20130101) Original (OR) Class
G06F 9/44521 (20130101)
G06F 21/00 (20130101)
G06F 21/50 (20130101)
G06F 21/51 (20130101)
G06F 21/52 (20130101)
G06F 21/64 (20130101)
G06F 21/577 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11288320 Beller et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Charles Beller (Baltimore, Maryland);  Christopher Ackermann (Fairfax, Virginia);  Kristen Summers (Takoma Park, Maryland);  Rob High (Round Rock, Texas);  David McQueeney (Yorktown Heights, New York)
ABSTRACT Embodiments for identifying entities relevant to queries are provided. At least one query is received from a user. The at least one query is associated with at least one entity. Results of the at least one query are analyzed to identify related entities. The related entities are analyzed based on a relevancy score and an information enhancement score for each of the related entities to generate a ranking of the related entities. At least one of the related entities is provided to the user based on the ranking of the related entities.
FILED Wednesday, June 05, 2019
APPL NO 16/432732
ART UNIT 2156 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 16/24578 (20190101)
G06F 16/90324 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11288406 Tran et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Strategic Systems Programs (SSP)
APPLICANT(S) The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S) The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts)
INVENTOR(S) Nhut Tran (Natick, Massachusetts);  J. Ryan Prince (Stow, Massachusetts);  Brian Nugent (Acton, Massachusetts);  Elliot Greenwald (Cambridge, Massachusetts)
ABSTRACT An embodiment is directed to a hardware circuit for performing operations on data transmitted between a processor and memory. The hardware circuit includes a first interface communicatively coupled to the processor. The first interface configured to emulate a first protocol of the memory. The hardware circuit further includes a second interface communicatively coupled to the memory. The second interface configured to emulates a second protocol of the processor. The hardware circuit also includes hardware logic configured with a bi-directional path, such that each of the first and second interfaces is associated with a different direction of the bi-directional path. The bi-directional path is configured to execute an operation on data received at both the first interface and the second interface.
FILED Friday, November 15, 2019
APPL NO 16/685678
ART UNIT 2435 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 9/45508 (20130101)
G06F 21/79 (20130101) Original (OR) Class
G06F 21/82 (20130101)
G06F 21/602 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11288537 McCloskey et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Honeywell International Inc. (Morris Plains, New Jersey)
ASSIGNEE(S) Honeywell International Inc. (Charlotte, North Carolina)
INVENTOR(S) Scott McCloskey (Minneapolis, Minnesota);  Keigo Hirakawa (Dayton, Ohio)
ABSTRACT A system and process to determine whether a digital image has been manipulated involves determining expected locations of non-standard pixels in the digital image, and determining a feature for evaluating the non-standard pixels. The feature in pixels of the digital image that are located at the expected locations of non-standard pixels is then measured, and a statistical measure of the feature of pixels in the digital image that are located at the expected locations of non-standard pixels is evaluated. The digital image is assessed to determine a probability that the digital image includes a manipulated portion, based on the statistical measure. The system and process can also determine a make and model of an image sensing device via an examination of the non-standard pixels.
FILED Friday, February 07, 2020
APPL NO 16/785337
ART UNIT 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00577 (20130101)
G06K 9/4642 (20130101)
G06K 9/6202 (20130101)
G06K 9/6212 (20130101) Original (OR) Class
G06K 9/6256 (20130101)
G06K 9/6277 (20130101)
G06K 2009/00583 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11288818 Daniilidis et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
INVENTOR(S) Konstantinos Daniilidis (Wynnewood, Pennsylvania);  Alex Zihao Zhu (Philadelphia, Pennsylvania)
ABSTRACT A method for prediction of an indication of motion using input from an event-based camera includes receiving events captured by an event-based camera, wherein each of the events represents a location of a change in pixel intensity, a polarity of the change, and a time. The method further includes discretizing the events into time discretized event volumes, each of which contain events that occur within a specified time range. The method further includes providing the time discretized event volumes as input to an encoder-decoder neural network trained to predict an indication of motion using a loss function that measures quality of image deblurring; generating, using the neural network, a prediction of the indication of motion. The method further includes using the prediction of the indication of motion in a machine vision application.
FILED Wednesday, February 19, 2020
APPL NO 16/795079
ART UNIT 2637 — Optical Communications
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/0472 (20130101)

Image Data Processing or Generation, in General
G06T 7/246 (20170101) Original (OR) Class
G06T 2207/20084 (20130101)
G06T 2207/30252 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11288856 Lu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Aviation & Missile Center (CCDC AVMC)
APPLICANT(S) INTELLIGENT FUSION TECHNOLOGY, INC. (Germantown, Maryland)
ASSIGNEE(S) INTELLIGENT FUSION TECHNOLOGY, INC. (Germantown, Maryland)
INVENTOR(S) Jingyang Lu (Germantown, Maryland);  Yiran Xu (Germantown, Maryland);  Dan Shen (Germantown, Maryland);  Nichole Sullivan (Germantown, Maryland);  Genshe Chen (Germantown, Maryland);  Khanh Pham (Kirtland AFB, New Mexico);  Erik Blasch (Arlington, Virginia)
ABSTRACT The present disclosure provides a method for wave propagation prediction based on a 3D ray tracing engine and machine-learning based dominant ray selection. The method includes receiving, integrating, and processing input data. Integrating and processing the input data includes dividing a cone of the original millimeter wave (mmWave) into a plurality of sub cones; determining a contribution weight of rays coming from each sub cone to the received signal strength (RSS) at a receiving end of interest; and determining rays coming from one or more sub cones that have a total contribution weight to the RSS larger than a preset threshold value as dominant rays using a neural network obtained through a machine learning approach. The method further includes performing ray tracing based on the input data and the dominant rays to predict wave propagation.
FILED Tuesday, November 05, 2019
APPL NO 16/674929
ART UNIT 2619 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101)
G06N 20/00 (20190101)

Image Data Processing or Generation, in General
G06T 15/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11288977 Howard et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) HRL LABORATORIES, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Michael D. Howard (Westlake Village, California);  Praveen K. Pilly (West Hills, California)
ABSTRACT In an embodiment of the present invention, a method for generating a prediction of ability of a subject to perform a task in a future time step includes receiving performance data corresponding to a performance of the subject on the task; receiving a plurality of biometric inputs computed based on physiological data during the performance of the subject on the task; identifying a numerical relationship between the performance data and the plurality of biometric inputs; generating a modulation parameter for each of the plurality of biometric inputs based on the identified numerical relationship; loading a plurality of state variable inputs produced by a generic model of performance; and generate the prediction of ability to perform the task at the prediction time, generated by a trained performance predictor based on biometric inputs predicted based on the modulation parameters.
FILED Friday, August 10, 2018
APPL NO 16/100921
ART UNIT 3715 — Amusement and Education Devices
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 20/00 (20190101)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 9/08 (20130101)
G09B 9/052 (20130101)
G09B 19/0069 (20130101)
G09B 19/165 (20130101)
G09B 19/167 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11289175 Srinivasa et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) HRL LABORATORIES LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Narayan Srinivasa (Oak Park, California);  Qin Jiang (Park Oaks, California)
ABSTRACT A method is disclosed. The method models a plurality of visual cortex neurons, models one or more connections between at least two visual cortex neurons in the plurality of visual cortex neurons, assigns synaptic weight value to at least one of the one or more connections, simulates application of one or more electrical signals to at least one visual cortex neuron in the plurality of visual cortex neurons, adjusts the synaptic weight value assigned to at least one of the one or more connection based on the one or more electrical signals, and generates an orientation map of the plurality of visual cortex neurons based on the adjusted synaptic weight values.
FILED Friday, November 30, 2012
APPL NO 13/691130
ART UNIT 2124 — AI & Simulation/Modeling
CURRENT CPC
Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 5/00 (20190201) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11289301 Zhang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Tiezhi Zhang (St. Louis, Missouri);  Praneeth Kandlakunta (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Tiezhi Zhang (St. Louis, Missouri);  Praneeth Kandlakunta (St. Louis, Missouri)
ABSTRACT A multi-pixel x-ray source is provided. The x-ray source includes a plurality of transmission target assemblies. The transmission target assembly includes a tungsten target and a diamond substrate. The substrate includes a first transmission surface and a second transmission surface opposite first transmission surface. The substrate further includes a first side surface and a second side surface disposed between the first and second transmission surfaces. The target covers the first transmission surface of the substrate. The transmission target assembly further includes a base. The base surrounds the first and second side surfaces of substrate, exposing a collimator surface of the second transmission surface and the target. The transmission target assembly is configured to transmit x-ray generated by the target through the target and the substrate.
FILED Friday, November 06, 2020
APPL NO 17/091744
ART UNIT 2884 — Optics
CURRENT CPC
Electric Digital Data Processing
G06F 30/20 (20200101)

Electric Discharge Tubes or Discharge Lamps
H01J 35/12 (20130101)
H01J 35/116 (20190501) Original (OR) Class
H01J 2235/081 (20130101)
H01J 2235/083 (20130101)

X-ray Technique
H05G 1/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11289444 Esler et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) David Richard Esler (Gloversville, New York);  Nancy Cecelia Stoffel (Niskayuna, New York)
ABSTRACT A sensor assembly includes a die substrate and a metalized layer formed on the die substrate. The metalized layer is formed of a first metal material and includes a bonding pad to facilitate electrically coupling the sensor assembly to a sensor system. A remetalized bump is formed on the bonding pad of a second metal material and is electrically coupled to the metalized layer. An adhesive is applied to the remetalized bump and facilitates mechanically coupling the sensor assembly to the sensor system.
FILED Friday, December 13, 2019
APPL NO 16/713437
ART UNIT 2816 — Semiconductors/Memory
CURRENT CPC
Microstructural Devices or Systems, e.g Micromechanical Devices
B81B 7/0006 (20130101)
B81B 2207/098 (20130101)

Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems
B81C 1/00301 (20130101)
B81C 2203/032 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 24/05 (20130101)
H01L 24/08 (20130101)
H01L 24/11 (20130101)
H01L 24/13 (20130101)
H01L 24/32 (20130101)
H01L 24/73 (20130101) Original (OR) Class
H01L 24/92 (20130101)
H01L 41/0475 (20130101)
H01L 2224/05124 (20130101)
H01L 2224/05686 (20130101)
H01L 2224/9211 (20130101)
H01L 2224/13124 (20130101)
H01L 2224/13144 (20130101)
H01L 2224/13147 (20130101)
H01L 2224/13164 (20130101)
H01L 2224/13169 (20130101)
H01L 2224/16157 (20130101)
H01L 2224/16227 (20130101)
H01L 2224/32157 (20130101)
H01L 2224/32227 (20130101)
H01L 2224/73104 (20130101)
H01L 2224/73204 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11289757 Nemanick et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S) The Aerospace Corporation (El Segundo, California)
ASSIGNEE(S) THE AEROSPACE CORPORATION (El Segundo, California)
INVENTOR(S) Eric Joseph Nemanick (Santa Monica, California);  Henry Helvajian (Pasadena, California);  Brian Shen (Hawthorne, California)
ABSTRACT Describe herein is an energy storage system that includes a battery and a heat source. The battery harvests waste heat from the heat source to keep itself warm while storing electrical energy generated from a heat to energy transforming source. If the heat source is radioactive (e.g. radioisotope decay) a radiation hard battery is intimately connected to a waste heat source. The radiation hard battery harvests waste heat from the heat source to warm itself and to shield the radiation.
FILED Wednesday, October 16, 2019
APPL NO 16/654105
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 35/32 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/46 (20130101)
H01M 10/66 (20150401) Original (OR) Class
H01M 10/0525 (20130101)
H01M 10/0562 (20130101)
H01M 10/615 (20150401)
H01M 10/653 (20150401)
H01M 10/659 (20150401)
H01M 2300/0074 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11290181 Meyers et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Office (CCDC ARO)
APPLICANT(S) U.S. Army Combat Capabilities Development Command, Army Research Labortary (Adelphi, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Ronald E. Meyers (Columbia, Maryland);  Keith S. Deacon (Columbia, Maryland)
ABSTRACT Measurement of entangled photon quantum wavefunction properties is vital for studying the fundamentals of entanglement and for future applications in quantum communications, quantum metrology, quantum sensing and imaging. Despite its importance, measuring the wavefunction is difficult, particularly in pulsed and other systems with system features and wavefunctions changing in space and time. This invention uses ghost imaging techniques to directly measure the entangled photon wavefunction of pulsed origin temporal and polarization entangled photons. The invention may be used to improve wavefunction quality after propagation through turbulent or scattering media.
FILED Thursday, March 18, 2021
APPL NO 17/205117
ART UNIT 2636 — Optical Communications
CURRENT CPC
Transmission
H04B 10/70 (20130101)
H04B 10/079 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11290212 Hutchinson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Meredith N. Hutchinson (Washington, District of Columbia);  Jonathan M. Nichols (Crofton, Maryland);  Gustavo K. Rohde (Crozet, Virginia);  Nicole Menkart (Potomac, Maryland);  Geoffrey A. Cranch (Fairfax Station, Virginia)
ABSTRACT Methods, apparatuses, and systems for calculating time delays by a Wasserstein approach are provided. A plurality of signals are recorded by a plurality of sensors (three or more), respectively, and received at a controller. The plurality of signals recorded by the plurality of sensors are generated in response to a signal emitted by a source. The plurality of signals are converted into a plurality of probability density functions. A cumulative distribution transform for each of the plurality of probability density functions is calculated. A time delay for each unique pair of the plurality of sensors is calculated by minimizing a Wasserstein distance between two cumulative distribution transforms corresponding to the unique pair of the plurality of sensors.
FILED Thursday, June 18, 2020
APPL NO 16/905842
ART UNIT 2473 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 1/0631 (20130101)
H04L 1/0681 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11290338 DeCleene et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire);  University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Brian DeCleene (North Reading, Massachusetts);  Anirudh Sabnis (Amherst, Massachusetts);  Ramesh K. Sitaraman (Amherst, Massachusetts);  Donald Towsley (Amherst, Massachusetts);  Paul Vines (Leesburg, Virginia)
ABSTRACT Techniques and architecture are disclosed for inferring a unified topological model of a hidden topology comprising dispersing data packets from a source to at least one receiver, and collecting individual end-to-end packet statistics; collecting aggregate end-to-end statistical measurements between a plurality of enclaves situated at an edge of an unknown network; identifying shared path correlations relating to shared links traversed between at least one root enclave and one or more leaf enclaves; constructing topological metrics as a directed tree corresponding to shared path correlations; inferring a unified topological model and routing paths of the unknown network based on the plurality of topological metrics collected by the plurality of enclaves; validating consistency between the subsequent end-to-end statistical measurements and the unified topological model of the hidden topology; and updating the inferred unified topological model of the hidden topology in accordance with observed inconsistencies.
FILED Monday, June 08, 2020
APPL NO 16/895738
ART UNIT 2443 — Computer Networks
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 41/12 (20130101) Original (OR) Class
H04L 41/16 (20130101)
H04L 41/145 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11290426 Roy
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Radhika Roy (Howell, New Jersey)
ABSTRACT Various embodiments that pertain to an enterprise network that employs a block chain portion and a non-block chain portion. For a single transaction, a header of the transaction can be sent over the block chain network and the non-header of the transaction can be sent over the non-block chain network. A hash-based cuckoo filter can be used for communication of the header along the block chain network.
FILED Monday, June 17, 2019
APPL NO 16/442627
ART UNIT 2497 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/0643 (20130101)
H04L 9/3242 (20130101)
H04L 63/0414 (20130101) Original (OR) Class
H04L 63/0428 (20130101)
H04L 2209/38 (20130101)
H04L 2463/041 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11290498 Soroush et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Palo Alto Research Center Incorporated (Palo Alto, California)
ASSIGNEE(S) Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S) Hamed Soroush (San Jose, California);  Shantanu Rane (Menlo Park, California)
ABSTRACT The system generates evidence of a recommended configuration for a distributed system based on a plurality of configuration parameters. The system displays, on a screen of a user device, the evidence, which includes a list of configuration parameters, including a name, a current value, and a recommended value for a respective configuration parameter. The recommended value is obtained based on a strategy for optimizing security, functionality, or both. The system further displays interactive elements which allow the user to: view a resolution of a pair of mutually incompatible constraints resulting in the recommended value for the respective configuration parameter, wherein the resolution includes a name of the configuration parameter removed from the list and a reason for the removal; and view information associated with each of the pair of mutually incompatible constraints, wherein the information includes a name, a goal, a security impact, and a description of the constraint.
FILED Thursday, July 09, 2020
APPL NO 16/925063
ART UNIT 2435 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 16/252 (20190101)
G06F 21/577 (20130101)
G06F 2221/034 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101)
G06N 5/04 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/205 (20130101) Original (OR) Class
H04L 63/1433 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11284858 Huang et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico)
INVENTOR(S) Lianjie Huang (Los Alamos, New Mexico);  Kai Gao (Los Alamos, New Mexico);  Yunsong Huang (Los Alamos, New Mexico)
ABSTRACT A method for plane-wave or fan-beam ultrasound tomography includes: controlling, by a processor, a multi-channel ultrasound array controller to control a linear ultrasound transducer array to emit plane-wave or fan-beam ultrasound into a biological tissue, the linear ultrasound transducer array including a plurality of transducers; receiving, by the processor, plane-wave or fan-beam ultrasound waveform data from the transducers, the plane-wave or fan-beam ultrasound waveform data including reflections of the plane-wave or fan-beam ultrasound from the biological tissue; computing, by the processor, a synthetic ultrasound-waveform inversion from the received plane-wave or fan-beam ultrasound waveform data; and computing, by the processor, an image of the biological tissue from the synthetic ultrasound-waveform inversion.
FILED Tuesday, July 02, 2019
APPL NO 16/460899
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/08 (20130101)
A61B 8/13 (20130101) Original (OR) Class
A61B 8/4483 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/0672 (20130101)
G01N 2291/02466 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285165 DeNardo et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Sally J. DeNardo (El Macero, California);  Gerald L. DeNardo (El Macero, California);  Rodney L. Balhorn (Livermore, California)
ABSTRACT This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use of antibodies. SHALs typically comprise a multiplicity of ligands that each bind different region son the target molecule. The ligands are joined directly or through a linker thereby forming a polydentate moiety that typically binds the target molecule with high selectivity and avidity.
FILED Wednesday, April 08, 2020
APPL NO 16/843783
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/675 (20130101) Original (OR) Class
A61K 47/55 (20170801)
A61K 47/60 (20170801)
A61K 47/64 (20170801)
A61K 47/545 (20170801)
A61K 47/645 (20170801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285430 Lail et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) Research Triangle Institute (Research Triangle Park, North Carolina)
ASSIGNEE(S) Research Triangle Institute (Research Triangle Park, North Carolina)
INVENTOR(S) Marty Lail (Raleigh, North Carolina);  Aravind Villava Rayer Rabindran (Morrisville, North Carolina);  Samuel John Thompson (Chapel Hill, North Carolina)
ABSTRACT The disclosure provides methods and systems for decreasing nitrosamine content, e.g., in the context of non-aqueous solvent systems. It includes a method including receiving a non-aqueous solvent system and contacting the non-aqueous solvent system with a composition including one or more alkoxides to give a treated solvent system having a nitrosamine content that is lower than the starting nitrosamine content. Similarly, it includes a system including a first unit configured to remove undesirable components from a gas stream; a second unit holding a composition including one or more alkoxides, and a conduit to connect these units.
FILED Tuesday, January 21, 2020
APPL NO 16/748111
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 53/18 (20130101)
B01D 53/1425 (20130101) Original (OR) Class
B01D 53/1475 (20130101)
B01D 2252/204 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285534 Yacout et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Abdellatif M. Yacout (Naperville, Illinois);  Sumit Bhattacharya (Darien, Illinois)
ABSTRACT A method loading powder into a mold can include immersing the mold comprising one or more microchannels into a suspension comprising the powder and a surfactant suspended in a dispersant, wherein the powder comprises particles having an average particle size of less than 100 μm, wherein the mold is substantially entirely covered by the suspension; heating the suspension having the mold immersed therein under a temperature condition suitable to lower the stability of the particles of the powder in the suspension such that the particles settle out of solution and into the one or more microchannels; and applying an ultrasonic wave to the heated suspension to further settle the particles of the powder into the one or more microchannels thereby filling the one or more microchannels of the mold with the powder.
FILED Friday, September 28, 2018
APPL NO 16/147347
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/0022 (20130101)
B22F 1/0074 (20130101)
B22F 3/004 (20130101) Original (OR) Class
B22F 3/093 (20130101)
B22F 2202/01 (20130101)
B22F 2301/10 (20130101)
B22F 2301/15 (20130101)
B22F 2302/253 (20130101)
B22F 2304/10 (20130101)
B22F 2304/054 (20130101)
B22F 2304/056 (20130101)
B22F 2304/058 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 43/01 (20130101)
C01G 56/00 (20130101)

Alloys
C22C 28/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285635 Terrani et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Kurt A. Terrani (Knoxville, Tennessee);  Michael P. Trammell (Knoxville, Tennessee);  Brian C. Jolly (Knoxville, Tennessee)
ABSTRACT A method for the manufacture of a three-dimensional object using a refractory matrix material is provided. The method includes the additive manufacture of a green body from a powder-based refractory matrix material followed by densification via chemical vapor infiltration (CVI). The refractory matrix material can be a refractory ceramic (e.g., silicon carbide, zirconium carbide, or graphite) or a refractory metal (e.g., molybdenum or tungsten). In one embodiment, the matrix material is deposited according to a binder-jet printing process to produce a green body having a complex geometry. The CVI process increases its density, provides a hermetic seal, and yields an object with mechanical integrity. The residual binder content dissociates and is removed from the green body prior to the start of the CVI process as temperatures increase in the CVI reactor. The CVI process selective deposits a fully dense coating on all internal and external surfaces of the finished object.
FILED Wednesday, July 31, 2019
APPL NO 16/527317
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 3/1007 (20130101)
B22F 3/1021 (20130101)
B22F 7/02 (20130101)
B22F 2301/20 (20130101)
B22F 2302/105 (20130101)
B22F 2998/10 (20130101)

Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster
B28B 1/001 (20130101) Original (OR) Class

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/52 (20130101)
C04B 35/573 (20130101)
C04B 35/5622 (20130101)
C04B 2235/77 (20130101)
C04B 2235/614 (20130101)

Nuclear Reactors
G21C 3/324 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285704 Stadermann et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC. (Livermore, California)
INVENTOR(S) Michael Stadermann (Pleasanton, California);  Patrick Campbell (Oakland, California);  Philip E. Miller (Livermore, California);  Chantel Aracne-Ruddle (Livermore, California);  Sung Ho Kim (Livermore, California);  Francisco J. Espinosa-Loza (Bellevue, Washington)
ABSTRACT According to one embodiment, a product includes a composite film comprising a polymer layer directly adjacent a graphene layer. According to another embodiment, a process includes layering a graphene layer onto a polymer layer to form a composite film.
FILED Thursday, September 07, 2017
APPL NO 15/698473
ART UNIT 1783 — Miscellaneous Articles, Stock Material
CURRENT CPC
Producing Particular Articles From Plastics or From Substances in a Plastic State
B29D 99/005 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 9/007 (20130101)
B32B 18/00 (20130101)
B32B 27/06 (20130101) Original (OR) Class
B32B 37/14 (20130101)
B32B 2309/105 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/184 (20170801)
C01B 32/194 (20170801)

Technical Subjects Covered by Former US Classification
Y10T 428/30 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286277 Tezcan et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Faik Akif Tezcan (La Jolla, California);  Yuta Suzuki (Tsuruoka, Japan)
ABSTRACT Polypeptide assemblies and building blocks and methods for making them are provided.
FILED Thursday, July 14, 2016
APPL NO 15/746789
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 1/306 (20130101)
C07K 2/00 (20130101) Original (OR) Class
C07K 2319/00 (20130101)
C07K 2319/21 (20130101)
C07K 2319/60 (20130101)
C07K 2319/735 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/16 (20130101)
C12N 9/88 (20130101)
C12N 15/1031 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286337 Bae et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Rensselaer Polytechnic Institute (Troy, New York)
ASSIGNEE(S) Rensselaer Polytechnic Institute (Troy, New York)
INVENTOR(S) Chulsung Bae (Cohoes, New York);  Woo-Hyung Lee (Siheung-Si, South Korea)
ABSTRACT Embodiments of the invention relate to a novel class of polymers with superior mechanical properties and chemical stability, as compared to known polymers. These polymers are particularly well suited for use in anion exchange membranes (AEMs), including those employed in fuel cells. Novel methods for the manufacture of these polymers are also described.
FILED Wednesday, August 28, 2019
APPL NO 16/553965
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 29/00 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 10/00 (20130101)
C08G 61/02 (20130101) Original (OR) Class
C08G 2261/20 (20130101)
C08G 2261/45 (20130101)
C08G 2261/124 (20130101)
C08G 2261/146 (20130101)
C08G 2261/312 (20130101)
C08G 2261/332 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/14 (20130101)
C09D 165/00 (20130101)

Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 13/08 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 8/1004 (20130101)
H01M 8/1039 (20130101)
H01M 8/1072 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 70/50 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286340 Miyake et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Colorado State University Research Foundation (Fort Collins, Colorado)
ASSIGNEE(S) Colorado State University Research Foundation (Fort Collins, Colorado)
INVENTOR(S) Garret Miyake (Fort Collins, Colorado);  Ryan M. Pearson (Berkeley, California);  Matthew D. Ryan (Berkeley, California)
ABSTRACT The present invention provides efficient processes for preparing brush polymers. In general, the process comprises three distinct reaction steps utilizing two separate catalysts. In the first step, the initiating compound comprising norbornene is contacted with a silane in the presence of a catalyst, thereby forming a silated intermediate. This silated intermediate is then contacted with a monomer in the presence of a catalyst via Group Transfer Polymerization (GTP). The resulting compound from GTP is contacted with a ring opening metathesis polymerization (ROMP) catalyst to prepare the brush polymer. Surprisingly, the brush polymers obtained from the above process are accessed in an efficient and rapid GTP methodology as compared to prior methods.
FILED Wednesday, January 29, 2020
APPL NO 16/775755
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 61/124 (20130101)
C08G 61/125 (20130101) Original (OR) Class
C08G 2261/128 (20130101)
C08G 2261/136 (20130101)
C08G 2261/418 (20130101)
C08G 2261/1426 (20130101)
C08G 2261/1432 (20130101)
C08G 2261/3241 (20130101)
C08G 2261/3245 (20130101)
C08G 2261/3324 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286419 Cozzan et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Clayton J. Cozzan (Goleta, California);  Steven P. DenBaars (Goleta, California);  Ram Seshadri (Goleta, California)
ABSTRACT A method for fabricating a composite useful in a white light emitting device, includes mixing a phosphor and a filler to form a mixture; sintering the mixture (e.g., using spark plasma sintering) to form a composite; and annealing the composite to reduce oxygen vacancies and improve optical properties of the composite. Also disclosed is a white light emitting device including a laser diode or light emitting diode optically pumping the phosphor in the composite to produce white light. The composite fabricated using the method (and having. e.g., at most 50% phosphor by weight) can (1) reduce an operating temperature of the phosphor by 55 degrees, (2) increase an external quantum efficiency (e.g., by at least 15%) of the white light emitting device, and (3) result in color points and quality of the white light that is equal to or improved, as compared to without the filler.
FILED Monday, July 31, 2017
APPL NO 16/320295
ART UNIT 2884 — Optics
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/10 (20130101)
C04B 35/44 (20130101)
C04B 35/117 (20130101)
C04B 35/645 (20130101)
C04B 2235/77 (20130101)
C04B 2235/80 (20130101)
C04B 2235/662 (20130101)
C04B 2235/664 (20130101)
C04B 2235/666 (20130101)
C04B 2235/3217 (20130101)
C04B 2235/3222 (20130101)
C04B 2235/3225 (20130101)
C04B 2235/3229 (20130101)
C04B 2235/6562 (20130101)
C04B 2235/6565 (20130101)
C04B 2235/6567 (20130101)
C04B 2235/6581 (20130101)
C04B 2235/6582 (20130101)
C04B 2235/9607 (20130101)
C04B 2235/9646 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/02 (20130101) Original (OR) Class
C09K 11/7774 (20130101)

Non-electric Light Sources Using Luminescence; Light Sources Using Electrochemiluminescence; Light Sources Using Charges of Combustible Material; Light Sources Using Semiconductor Devices as Light-generating Elements; Light Sources Not Otherwise Provided for
F21K 9/64 (20160801)
F21K 9/68 (20160801)

Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to the Form or the Kind of the Light Sources or of the Colour of the Light Emitted
F21Y 2115/10 (20160801)
F21Y 2115/30 (20160801)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/055 (20130101)
H01L 33/501 (20130101)
H01L 33/502 (20130101)
H01L 2933/0041 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 33/14 (20130101)
H05B 33/20 (20130101)

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 20/00 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286432 Timko et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
Bioenergy Technologies Office (BETO)
Office of Science (DOE-SC)
APPLICANT(S) Worcester Polytechnic Institute (Worcester, Massachusetts)
ASSIGNEE(S) Worcester Polytechnic Institute (Worcester, Massachusetts)
INVENTOR(S) Michael T. Timko (Arlington, Massachusetts);  Geoffrey A. Tompsett (Shrewsbury, Massachusetts);  Alex R. Maag (Ithaca, New York)
ABSTRACT Catalyst composition and parameters for catalytic hydrothermal liquefaction of biomass to bio-oil fuels target municipal solid waste (MSW) rather than lignin rich plant waste typically sought for bio-oil production. An HTL (Hydrothermal Liquefaction) reactor generates bio-fuel from municipal solid waste (MSW), including receiving, in the HTL reactor, non-lignin based waste from a municipal processing stream, and adding a solvent for extracting sugars from green waste components of the municipal processing stream. The reactor extracts a liquid from the received waste, and converts water soluble products in the liquid into oil soluble products via C—C (carbon-to-carbon) coupling reactions. A catalyst added to the resulting aqueous stream recovers a beneficial oil product, and is optimized by tuning acid and base sites on the solid catalyst.
FILED Thursday, September 26, 2019
APPL NO 16/583582
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/002 (20130101)
B01J 23/10 (20130101)
B01J 37/0201 (20130101)

Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes
C10G 53/06 (20130101) Original (OR) Class

Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters
C10L 1/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286494 Benning et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) Christoph Benning (East Lansing, Michigan);  Kun Wang (East Lansing, Michigan)
ABSTRACT Described herein are transgenic plants with increased oil content that exhibit enhanced expression of plastid-specific lipases (e.g., PLIP1). The manufacture of lipids can be enhanced by expression of FAD4.
FILED Thursday, March 29, 2018
APPL NO 16/498663
ART UNIT 1662 — Plants
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/20 (20130101)
C12N 9/0071 (20130101)
C12N 15/8247 (20130101) Original (OR) Class

Enzymes
C12Y 114/19 (20130101)
C12Y 301/01032 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286783 Martin et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) Raytheon Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S) Thomas J. Martin (East Hampton, Connecticut);  John E. Holowczak (South Windsor, Connecticut);  Matthew B. Kennedy (Vernon, Connecticut);  Paul F. Croteau (Columbia, Connecticut);  Paul Attridge (Colchester, Connecticut)
ABSTRACT An airfoil includes an airfoil section that has an airfoil wall that surrounds a cavity. The airfoil wall includes an exterior monolithic ceramic shell and an interior CMC liner that has CMC plies. An outermost ply of the CMC plies forms tabs that are raised from an underlying ply so as to define a slot. The exterior monolithic ceramic shell includes an underlapping shell piece and an overlapping shell piece. The underlapping shell piece has a portion disposed in the slot and bonded with the tabs. The overlapping shell piece extends over the tabs and is bonded to the tabs. There are channels bounded by adjacent ones of the tabs, the underlapping shell piece, and the overlapping shell piece. Channel orifices through the CMC liner connect the cavity and the channels.
FILED Monday, April 27, 2020
APPL NO 16/859198
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/147 (20130101) Original (OR) Class
F01D 5/282 (20130101)
F01D 5/284 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2300/6033 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287079 Biswas et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Kaushik Biswas (Knoxville, Tennessee);  Pengfei Cao (Knoxville, Tennessee);  Tomonori Saito (Knoxville, Tennessee)
ABSTRACT A self-healing vacuum insulation panel and a method of manufacture are provided. The vacuum insulation panel includes a self-healing, multi-layer barrier film including a separator between a curing agent and a curable resin. Upon damage to the separator, the curing agent penetrates the separator due to a pressure differential across the barrier film and reacts with the curable resin to seal any cuts or punctures. The curing agent and the curable resin can be selected to have long term stability and a short reaction time with no need for external stimuli. As a result, the multi-layer barrier film can retain the internal vacuum and maintain a desirably low thermal conductivity using low-cost, commercially available epoxies and curing agents.
FILED Friday, January 17, 2020
APPL NO 16/746149
ART UNIT 1781 — Miscellaneous Articles, Stock Material
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 3/04 (20130101)
B32B 5/16 (20130101)
B32B 5/18 (20130101)
B32B 27/12 (20130101)
B32B 27/36 (20130101)
B32B 27/065 (20130101)
B32B 37/185 (20130101)
B32B 38/1858 (20130101)
B32B 2250/40 (20130101)
B32B 2255/10 (20130101)
B32B 2255/26 (20130101)
B32B 2255/28 (20130101)
B32B 2255/205 (20130101)
B32B 2266/06 (20130101)
B32B 2307/304 (20130101)
B32B 2307/762 (20130101)
B32B 2307/7246 (20130101)
B32B 2367/00 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 59/66 (20130101)
C08G 59/4042 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 167/02 (20130101)

Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General
F16L 59/065 (20130101) Original (OR) Class

Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for
F25D 23/065 (20130101)
F25D 2201/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287134 Berry
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Jonathan Dwight Berry (Simpsonville, South Carolina)
ABSTRACT A combustor may include a combustor liner and flow sleeve. A high pressure air cools an outer surface of the combustor liner via openings in the flow sleeve, creating a lower pressure air in an annulus between the combustor liner and the flow sleeve. A first fuel nozzle is positioned at a primary combustion zone, and a second fuel nozzle is positioned at a secondary combustion zone of the liner. A fuel source is configured to deliver a fuel to the fuel nozzles. The fuel nozzles produce a premixture of high pressure air and the fuel, and produce a mixture of the premixture and the lower pressure air, prior to introducing the mixture to a respective primary or secondary combustion zone of the combustor. The combustor provides improved fuel premixing and is fuel flexible, and reduces pressure drop requirements. The combustor is usable in a can, annular, or segmented annular combustor assembly.
FILED Tuesday, December 31, 2019
APPL NO 16/731207
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers
F23R 3/005 (20130101)
F23R 3/10 (20130101)
F23R 3/26 (20130101)
F23R 3/36 (20130101)
F23R 3/286 (20130101)
F23R 3/346 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287358 Nath et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Pulak Nath (Los Alamos, New Mexico);  Jackson Henry McFall (Los Alamos, New Mexico);  Dylan Chance Purcell (Los Alamos, New Mexico);  Jen-Huang Huang (Los Alamos, New Mexico)
ABSTRACT Devices that include a liquid chamber including at least two ports, wherein the opening of a first port is larger than the opening of a second port, an air chamber including at least one port, and a membrane located between the liquid chamber and the air chamber, and a pressure sensor coupled to the port in the air chamber are provided. Systems including the disclosed devices are also provided. The systems include liquid in the liquid chamber of the device. Methods of using the devices and systems include measuring one or more properties of a liquid by flowing the liquid through the liquid chamber of the system and measuring the pressure produced due to the difference in size of the ports in the liquid chamber.
FILED Monday, August 12, 2019
APPL NO 16/538561
ART UNIT 1799 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/14 (20130101)
G01N 11/08 (20130101) Original (OR) Class
G01N 33/5044 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287362 Kaduchak et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Gregory Kaduchak (Los Alamos, New Mexico);  Michael D. Ward (Los Alamos, New Mexico)
ABSTRACT The present invention is a method and apparatus for acoustically manipulating one or more particles.
FILED Wednesday, September 18, 2019
APPL NO 16/574745
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502761 (20130101)
B01L 2200/0636 (20130101)
B01L 2200/0652 (20130101)
B01L 2300/0838 (20130101)
B01L 2300/0864 (20130101)
B01L 2400/0439 (20130101)
B01L 2400/0487 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/1404 (20130101) Original (OR) Class
G01N 15/1459 (20130101)
G01N 15/1463 (20130101)
G01N 29/14 (20130101)
G01N 33/4833 (20130101)
G01N 33/48735 (20130101)
G01N 2001/4094 (20130101)
G01N 2015/142 (20130101)
G01N 2015/149 (20130101)
G01N 2015/1081 (20130101)
G01N 2015/1415 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287363 Kaduchak et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Gregory Kaduchak (Los Alamos, New Mexico);  Michael D. Ward (Los Alamos, New Mexico)
ABSTRACT The present invention provides systems and methods for using acoustic radiation pressure to fractionate particles within a fluid.
FILED Tuesday, October 15, 2019
APPL NO 16/653020
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502761 (20130101)
B01L 2200/0636 (20130101)
B01L 2200/0652 (20130101)
B01L 2300/0838 (20130101)
B01L 2300/0864 (20130101)
B01L 2400/0439 (20130101)
B01L 2400/0487 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/1404 (20130101) Original (OR) Class
G01N 15/1459 (20130101)
G01N 15/1463 (20130101)
G01N 29/14 (20130101)
G01N 33/4833 (20130101)
G01N 33/48735 (20130101)
G01N 2001/4094 (20130101)
G01N 2015/142 (20130101)
G01N 2015/149 (20130101)
G01N 2015/1081 (20130101)
G01N 2015/1415 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287381 Gu et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Lianhong Gu (Oak Ridge, Tennessee);  Jeffrey S. Riggs (LaFollette, Tennessee)
ABSTRACT A chlorophyll fluorescence measuring system having at least one spectrometer coupled to a data logger. The data logger provides direct control of the spectrometer and includes on-board memory for storage of target and reference spectrum data obtained by the spectrometer. The data logger may be coupled to an external computer that receives and analyzes target and reference spectrum data to determine SIF using a spectral fitting algorithm. The system may include a spectrometer aiming system coupled to and controlled by the data logger. The system may also include one or more environmental sensors configured to measure environment variables. The environmental sensors may be coupled to the data logger for control and data storage. The environmental data may be communicated to the external computer for use in the spectral fitting algorithm. The data logger may be connected to a network for remote monitoring and control.
FILED Friday, June 30, 2017
APPL NO 15/638473
ART UNIT 2864 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6486 (20130101) Original (OR) Class
G01N 2021/635 (20130101)
G01N 2021/6417 (20130101)
G01N 2021/6484 (20130101)
G01N 2021/8466 (20130101)
G01N 2201/08 (20130101)
G01N 2201/13 (20130101)
G01N 2201/0231 (20130101)
G01N 2201/0238 (20130101)
G01N 2201/0616 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287408 Karp et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Jason Harris Karp (Niskayuna, New York);  William Albert Challener (Glenville, New York)
ASSIGNEE(S) BAKER HUGHES, A GE COMPANY, LLC (Houston, Texas)
INVENTOR(S) Jason Harris Karp (Niskayuna, New York);  William Albert Challener (Glenville, New York)
ABSTRACT A gas detector sensor node includes a first sensor conductor having a terminal end, a second sensor conductor including an end section, and a coupler joining the terminal end of the first sensor conductor with the end section of the second sensor conductor. The coupler is permeable to gas.
FILED Tuesday, April 30, 2019
APPL NO 16/398665
ART UNIT 2883 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/0036 (20130101) Original (OR) Class

Optical Elements, Systems, or Apparatus
G02B 6/12 (20130101)
G02B 6/26 (20130101)
G02B 6/02328 (20130101)
G02B 6/02361 (20130101)
G02B 6/3833 (20130101)
G02B 2006/12102 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287463 Karin et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
Office of Electricity (DOE-OE)
APPLICANT(S) Palo Alto Research Center Incorporated (Palo Alto, California)
ASSIGNEE(S) Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S) Todd Karin (Los Gatos, California);  Peter Kiesel (Palo Alto, California);  Ajay Raghavan (Mountain View, California)
ABSTRACT A partial discharge (PD) transducer that includes a PD sensor configured to sense a PD event of an electrical system. At least one light emitting device (LED) is arranged in series with the PD sensor. The LED is configured to receive the electrical sensor signal from the PD sensor and to generate a light signal in response to the electrical sensor signal.
FILED Friday, December 28, 2018
APPL NO 16/235747
ART UNIT 2868 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 15/16 (20130101)
G01R 15/22 (20130101)
G01R 19/0084 (20130101)
G01R 31/1218 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287481 Weiss et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Xilectric, Inc. (Fall River, Massachusetts)
ASSIGNEE(S) Xilectric, Inc. (Fall River, Massachusetts)
INVENTOR(S) Steven E. Weiss (Auburndale, Massachusetts);  Charles R. Lemay (Portsmouth, New Hampshire);  Andrew Ferencz (Southborough, Massachusetts)
ABSTRACT Systems, devices, and methods of diagnosing an electrochemical cell using cyclic coulometry are discussed. An exemplary battery diagnostic system comprises a current generator to generate symmetric charge current and discharge current to excite an electrochemical cell, and a cyclic coulometer to evaluate performance of the electrochemical cell. The cyclic coulometer can adjust at least one of a charge time for applying the charge current, or a discharge time for applying the discharge current, to keep a monitored cell voltage toward a specific setpoint. The adjustment of charge or discharge time can be achieved by changing a current switch timing for reversing current from a first to a second current direction. The cyclic coulometer measures one or more electrical parameters during the charge or discharge cycle, and generates a performance metric using the measured electrical parameters.
FILED Wednesday, June 05, 2019
APPL NO 16/432331
ART UNIT 2851 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/367 (20190101)
G01R 31/388 (20190101)
G01R 31/3842 (20190101) Original (OR) Class

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/484 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/008 (20130101)
H02J 7/0078 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287506 Rouse et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Jerry W. Rouse (Albuquerque, New Mexico);  Daniel Bowman (Albuquerque, New Mexico);  Timothy Walsh (West Lafayette, Indiana)
ABSTRACT A method and apparatus for determining a direction of infrasound. Infrasound is received by a directional infrasound sensor comprising a plurality of channels and a plurality of sensor devices. Each channel in the plurality of channels comprises a single opening at a first end of the channel and a closed end opposite the opening. The opening of each channel in the plurality of channels is pointed in a different direction from the opening of each other channel in the plurality of channels. The plurality of sensor devices includes a sensor device at the closed end of each channel in the plurality of channels. Each sensor device in the plurality of sensor devices is configured to generate a sensor signal in response to pressure. The sensor signals generated by the plurality of sensor devices are processed to determine the direction of the infrasound received by the directional infrasound sensor.
FILED Friday, June 05, 2020
APPL NO 16/893675
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 3/801 (20130101)
G01S 3/8006 (20130101) Original (OR) Class
G01S 3/8034 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287536 Howell et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Stephen W. Howell (Bloomington, Indiana);  David W. Peters (Albuquerque, New Mexico);  Thomas Edwin Beechem, III (Albuquerque, New Mexico);  Isaac Ruiz (Albuquerque, New Mexico);  Richard Karl Harrison (Albuquerque, New Mexico);  Jeffrey B. Martin (Albuquerque, New Mexico)
ABSTRACT A radiation field is detected or imaged using one or more junction devices in which a two-dimensional conductor layer is capacitively coupled to a semiconductor absorber layer. In the junction devices, pixel-level amplification and read-out are accomplished through the photogating of the devices by absorption within the absorber layer while it is in a state of deep depletion. When the two-dimensional conductor is graphene, we refer to a device operating in that manner as a deeply depleted graphene-oxide-semiconductor (D2GOS) detector.
FILED Wednesday, October 17, 2018
APPL NO 16/162756
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 1/17 (20130101) Original (OR) Class
G01T 1/185 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/14659 (20130101)
H01L 29/1606 (20130101)
H01L 31/028 (20130101)
H01L 31/119 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11288095 Dutu et al.
FUNDED BY
Department of Energy (DOE)
Exascale Computing Project (ECP)
PathForward Project (PATHFORWARD)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Advanced Micro Devices, Inc. (Santa Clara, California)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Santa Clara, California)
INVENTOR(S) Alexandru Dutu (Bellevue, Washington);  Matthew D. Sinclair (Bellevue, Washington);  Bradford M. Beckmann (Bellevue, Washington);  David A. Wood (Austin, Texas)
ABSTRACT A technique for synchronizing workgroups is provided. The techniques comprise detecting that one or more non-executing workgroups are ready to execute, placing the one or more non-executing workgroups into one or more ready queues based on the synchronization status of the one or more workgroups, detecting that computing resources are available for execution of one or more ready workgroups, and scheduling for execution one or more ready workgroups from the one or more ready queues in an order that is based on the relative priority of the ready queues.
FILED Monday, September 30, 2019
APPL NO 16/588872
ART UNIT 2196 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 9/52 (20130101)
G06F 9/4881 (20130101) Original (OR) Class
G06F 2209/521 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11288194 Johns et al.
FUNDED BY
Department of Energy (DOE)
Office of Scientific and Technical Information (OSTI)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Charles R. Johns (Austin, Texas);  James A. Kahle (Austin, Texas);  Martin Ohmacht (Yorktown Heights, New York);  Changhoan Kim (Westchester, New York);  Jose R. Brunheroto (Mohegan Lake, New York);  Constantinos Evangelinos (Cambridge, Massachusetts);  Abdullah Kayi (Westchester, New York);  Alessandro Morari (New York, New York);  James C. Sexton (Yorktown Heights, New York);  Patrick D. Siegl (White Plains, New York)
ABSTRACT An approach is disclosed that maintains a consistent view of a virtual address by a local node which writes a first value to the virtual address and, after writing the first value, establishes a snapshot consistency state of the virtual address. The virtual address is shared amongst any number of processes and the processes includes a writing process and other processes that read from the virtual address. After writing the first value, the writing process writes a second value to the virtual address. Even after writing the second value, the first value is still visible to the other processes.
FILED Wednesday, December 12, 2018
APPL NO 16/217257
ART UNIT 2184 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 12/0815 (20130101) Original (OR) Class
G06F 2212/657 (20130101)
G06F 2212/1008 (20130101)
G06F 2212/1048 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11288208 Nair et al.
FUNDED BY
Department of Energy (DOE)
Office of Scientific and Technical Information (OSTI)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Ravi Nair (Briarcliff Manor, New York);  Charles R. Johns (Austin, Texas);  James A. Kahle (Austin, Texas);  Changhoan Kim (Westchester, New York);  Constantinos Evangelinos (Cambridge, Massachusetts);  Patrick D. Siegl (White Plains, New York)
ABSTRACT An approach is described that provides access to a named data element in a Coordination Namespace that is stored in a memory that is distributed amongst a set of nodes. A request of a name corresponding to the named data element is received from a requesting process and the approach responsively searches for the name in the Coordination Namespace. In response to determining an absence of data corresponding to the named data element, a pending state is indicated to the requesting process. In response to determining that the data corresponding to the named data element exists, a successful state is returned to the requesting process. In one embodiment, the successful state also includes providing the requesting process with access to the data corresponding to the named data element.
FILED Wednesday, December 12, 2018
APPL NO 16/218118
ART UNIT 2139 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 9/544 (20130101)
G06F 9/546 (20130101)
G06F 12/0284 (20130101)
G06F 12/0692 (20130101)
G06F 12/0824 (20130101)
G06F 12/1018 (20130101)
G06F 12/1072 (20130101) Original (OR) Class
G06F 13/1663 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11288424 Chen et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan);  UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) GM Global Technology Operations LLC (Detroit, Michigan);  UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Jian Chen (Oak Ridge, Tennessee);  Hui Huang (Oak Ridge, Tennessee);  Zhili Feng (Oak Ridge, Tennessee);  Blair Carlson (Ann Arbor, Michigan);  Hui-Ping Wang (Warren, Michigan);  Wayne Cai (Troy, Michigan)
ABSTRACT A method for accelerating an explicit finite element analysis (FEA) simulation of a modeled system or process includes performing an initial iteration of the FEA simulation according to a baseline time interval via an FEA computing network, and calculating a criteria ratio of a predetermined set of scaling criteria for the modeled system or process. The method includes determining a time-scaling factor using the criteria ratio via the FEA computing network as a function of the criteria ratio, and then applying the time-scaling factor to the baseline time interval to generate a scaled time interval. The scaled time interval accelerates simulation time of the FEA simulation. The method includes performing a subsequent iteration of the explicit FEA simulation at the scaled time interval using the FEA computing network. The process continues for subsequent iterations, with the time-scaling factor adapting with each iteration.
FILED Tuesday, June 25, 2019
APPL NO 16/451513
ART UNIT 2146 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 17/11 (20130101)
G06F 30/23 (20200101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 15/005 (20130101)
G06T 19/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11288434 Trujillo
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Kansas City National Security Campus (KCNSC)
NNSA Critical Mission Site
Operated by Honeywell Federal Manufacturing & Technologies (FM&T) at Kansas City, MO
APPLICANT(S) HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri)
ASSIGNEE(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S) Joshua Trujillo (Albuquerque, New Mexico)
ABSTRACT A computer-implemented method of generating randomized electrical interconnects for an electronic circuit comprises steps of receiving a netlist of nodes of electronic components to be connected, each connection between the nodes forming an electrical interconnect; determining a list of one or more path directions for each electrical interconnect; determining a plurality of path direction distances for each electrical interconnect; generating a plurality of segments for each electrical interconnect, each segment having one path direction and a length which are selected at random; calculating a sum of the lengths of all segments of the plurality of segments in each path direction each time a segment is generated for each electrical interconnect; removing one path direction from the list of path directions when a first condition is met; and stopping the generating a plurality of segments for each electrical interconnect when a second condition is met.
FILED Friday, September 04, 2020
APPL NO 17/012234
ART UNIT 2851 — Printing/Measuring and Testing
CURRENT CPC
Electric Digital Data Processing
G06F 30/392 (20200101) Original (OR) Class
G06F 30/394 (20200101)
G06F 30/398 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11289156 Frank et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Michael P. Frank (Albuquerque, New Mexico);  Erik Debenedictis (Albuquerque, New Mexico)
ABSTRACT A reversible memory element is provided. The reversible memory element comprises a reversible memory cell comprising a Josephson junction and a passive inductor. A ballistic interconnect is connected to the reversible memory cell by a bidirectional input/output port. A polarized input fluxon propagating along the ballistic interconnect exchanges polarity with a stationary stored fluxon in the reversible memory cell in response to the input fluxon reflecting off the reversible memory cell.
FILED Thursday, July 30, 2020
APPL NO 16/943613
ART UNIT 2827 — Semiconductors/Memory
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/0354 (20130101)

Static Stores
G11C 11/44 (20130101) Original (OR) Class
G11C 11/1673 (20130101)
G11C 11/1675 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 39/025 (20130101)
H01L 39/223 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11289213 Lahoda et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
APPLICANT(S) WESTINGHOUSE ELECTRIC COMPANY LLC (Cranberry Township, Pennsylvania)
ASSIGNEE(S) Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania)
INVENTOR(S) Edward J. Lahoda (Edgewood, Pennsylvania);  Frank A. Boylan (Ellwood City, Pennsylvania);  Ho Q. Lam (Verona, Pennsylvania);  Mitchell E. Nissley (Trafford, Pennsylvania);  Raymond E. Schneider (South Windsor, Connecticut);  Robert L. Oelrich (Columbia, South Carolina);  Sumit Ray (Columbia, South Carolina);  Radu Pomirleanu (Wexford, Pennsylvania);  Zeses Karoutas (Lexington, South Carolina);  Michael J. Hone (Prospect, Pennsylvania)
ABSTRACT A control rod for a nuclear fuel assembly is described herein that includes a neutron absorbing material having a melting point greater than 1500° C. that does not form a eutectic with a melting point less than 1500° C., and may further include a cladding material having a melting point greater than 1500° C. The cladding material is selected from the group consisting of silicon carbide, zirconium, a zirconium alloy, tungsten, and molybdenum. The absorbing material is selected from the group consisting of Gd2O3, Ir, B4C, Re, and Hf. The metal cladding or the absorbing material may be coated with an anti-oxidation coating of Cr with or without a Nb intermediate layer.
FILED Wednesday, August 01, 2018
APPL NO 16/051712
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 30/00 (20130101)

Nuclear Reactors
G21C 1/08 (20130101)
G21C 3/07 (20130101)
G21C 3/328 (20130101)
G21C 7/10 (20130101)
G21C 7/24 (20130101) Original (OR) Class
G21C 11/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11289231 Larsen, III et al.
FUNDED BY
Department of Energy (DOE)
Office of Environmental Management (DOE-EM)
Savannah River National Laboratory (SRNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Savannah River Nuclear Solutions, LLC (SRNS) at Aiken, SC
APPLICANT(S) SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (Aiken, South Carolina)
ASSIGNEE(S) Savannah River Nuclear Solutions, LLC (Aiken, South Carolina)
INVENTOR(S) George K. Larsen, III (Aiken, South Carolina);  Simona E. Hunyadi Murph (North Augusta, South Carolina)
ABSTRACT Radiation detectors and methods of using the radiation detectors that provide a route for surface decontamination during use are described. The detectors utilize light illumination of an internal surface during use. Light is in the longer UV-to-near-infrared spectra and desorbs contamination from internal surfaces of radiation detectors. The methods can be carried out while the detectors are in operation, preventing the appearance of the negative effects of radioactive and non-radioactive contamination during a detection regime and following a detection regime.
FILED Thursday, August 27, 2020
APPL NO 17/004646
ART UNIT 1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Cleaning in General; Prevention of Fouling in General
B08B 7/0057 (20130101)

Measurement of Nuclear or X-radiation
G01T 1/185 (20130101)
G01T 7/00 (20130101)

Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor
G21F 9/002 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11289248 Pathak et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Ames Laboratory (AL)
Federally Funded Research and Development Center (FFRDC)
Operated by Iowa State University (IASTATE) at Ames, IA
APPLICANT(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
ASSIGNEE(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S) Arjun K. Pathak (Ames, Iowa);  Yaroslav Mudryk (Ames, Iowa);  Oleksandr Dolotko (Ames, Iowa);  Vitalij K. Pecharsky (Ames, Iowa)
ABSTRACT A magnetocaloric material comprising a La—Fe—Si based alloy composition that is compositionally modified to include a small but effective amount of at least one of Al, Ga, and In to improve mechanical stability of the alloy (substantially reduce alloy brittleness), improve thermal conductivity, and preserve comparable or provide improved magnetocaloric effects. The alloy composition may be further modified by inclusion of at least one of Co, Mn, Cr, and V as well as interstitial hydrogen.
FILED Monday, February 11, 2019
APPL NO 16/501027
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 70/00 (20141201)

Alloys
C22C 33/04 (20130101)
C22C 38/02 (20130101)
C22C 38/005 (20130101)
C22C 38/06 (20130101)
C22C 2202/02 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/015 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11289640 Solovyov
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Brookhaven Technology Group, Inc. (Stony Brook, New York)
ASSIGNEE(S) Brookhaven Technology Group, Inc. (Stony Brook, New York)
INVENTOR(S) Vyacheslav Solovyov (Rocky Point, New York)
ABSTRACT A high-temperature superconducting filament and cable, and a method for manufacturing same. The substrate used to grow the superconducting layer is removed, and the exfoliated superconducting layer is coated with a protective layer, and then sliced into narrow strips. The strips are thereafter encapsulated with a conductive metal to provide a high-temperature superconducting filament. The filaments may be bundled together to provide a high-temperature superconducting cable.
FILED Friday, January 20, 2017
APPL NO 16/071772
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 12/06 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 39/143 (20130101)
H01L 39/248 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11289689 Du et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UTBATTELE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Zhijia Du (Knoxville, Tennessee);  Christopher James Janke (Oliver Springs, Tennessee);  Jianlin Li (Knoxville, Tennessee);  David L. Wood, III (Knoxville, Tennessee);  Claus Daniel (Knoxville, Tennessee)
ABSTRACT A method of making an electrode includes the step of mixing active material particles, radiation curable resin precursors, and electrically conductive particles to create an electrode precursor mixture. The electrode precursor mixture is electrostatically sprayed onto a current collector to provide an electrode preform. The electrode preform is heated and calendered to melt the resin precursor such that the resin precursor surrounds the active particles and electrically conductive particles. Radiation is applied to the electrode preform sufficient to cure the radiation curable resin precursors into resin.
FILED Monday, April 30, 2018
APPL NO 15/966840
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/0404 (20130101)
H01M 4/0419 (20130101) Original (OR) Class
H01M 4/0435 (20130101)
H01M 4/0471 (20130101)
H01M 4/621 (20130101)
H01M 4/1315 (20130101)
H01M 4/1391 (20130101)
H01M 4/1393 (20130101)
H01M 4/1397 (20130101)
H01M 4/13915 (20130101)
H01M 2004/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11289700 Whittingham et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) The Research Foundation for The State University of New York (Binghamton, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Binghamton, New York)
INVENTOR(S) M. Stanley Whittingham (Vestal, New York);  Jia Ding (Binghamton, New York)
ABSTRACT An electrode comprising: NaVOPO4 having orthorhombic crystalline symmetry and space group Pna21, as an active intercalation host material, wherein the electrode is capable of electrochemical insertion and release of greater than one sodium ion per vanadium, wherein the NaVOPO4 is formed by a solid phase synthesis process from a heated powdered mixture of ammonium metavanadate, ammonium phosphate monobasic, and potassium carbonate, to yield KVOPO4 having corner-sharing VO6 octahedra and PO4 tetrahedra, defining two types of tunnels comprising a first type of tunnel formed of rings of two PO4 tetrahedra and a second type of tunnel formed of rings of three PO4 tetrahedra and three VO6 octahedra, followed by substitution of the potassium ions with sodium ions.
FILED Monday, June 26, 2017
APPL NO 15/633240
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 31/006 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/72 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 14/18 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/01 (20180101)
C08K 3/04 (20130101)
C08K 3/32 (20130101)
C08K 2003/328 (20130101)

Compositions of Macromolecular Compounds
C08L 9/08 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 127/16 (20130101)
C09D 127/16 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/381 (20130101) Original (OR) Class
H01M 4/622 (20130101)
H01M 4/623 (20130101)
H01M 4/625 (20130101)
H01M 4/5825 (20130101)
H01M 10/054 (20130101)
H01M 2004/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11289701 Wang et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Amprius, Inc. (Fremont, California)
ASSIGNEE(S) Amprius, Inc. (Fremont, California)
INVENTOR(S) Weijie Wang (Sunnyvale, California);  Zuqin Liu (Sunnyvale, California);  Song Han (Foster City, California);  Jonathan Bornstein (Cupertino, California);  Constantin Ionel Stefan (San Jose, California)
ABSTRACT Provided herein are nanostructures for lithium ion battery electrodes and methods of fabrication. In some embodiments, a nanostructure template coated with a silicon coating is provided. The silicon coating may include a non-conformal, more porous layer and a conformal, denser layer on the non-conformal, more porous layer. In some embodiments, two different deposition processes, e.g., a PECVD layer to deposit the non-conformal layer and a thermal CVD process to deposit the conformal layer, are used. Anodes including the nanostructures have longer cycle lifetimes than anodes made using either a PECVD or thermal CVD method alone.
FILED Wednesday, May 13, 2020
APPL NO 15/931470
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/134 (20130101)
H01M 4/366 (20130101)
H01M 4/386 (20130101) Original (OR) Class
H01M 4/0428 (20130101)
H01M 4/1395 (20130101)
H01M 10/052 (20130101)
H01M 10/0525 (20130101)
H01M 2004/027 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11289876 Jayaraman et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Thorlabs, Inc. (Newton, New Jersey);  Praevium Research, Inc. (Santa Barbara, California)
ASSIGNEE(S) Thorlabs, Inc. (Newton, New Jersey);  Praevium Research, Inc. (Santa Barbara, California)
INVENTOR(S) Vijaysekhar Jayaraman (Goleta, California);  Kevin Lascola (Columbia, Maryland);  Stephen Segal (Columbia, Maryland);  Fredrick Towner (Fulton, Maryland);  Alex Cable (Newton, New Jersey)
ABSTRACT Disclosed is an optically pumped vertical cavity laser structure operating in the mid-infrared region, which has demonstrated room-temperature continuous wave operation. This structure uses a periodic gain active region with type I quantum wells comprised of InGaAsSb, and barrier/cladding regions which provide strong hole confinement and substantial pump absorption. A preferred embodiment includes at least one wafer bonded GaAs-based mirror. Several preferred embodiments also include means for wavelength tuning of mid-IR VCLs as disclosed, including a MEMS-tuning element. This document also includes systems for optical spectroscopy using the VCL as disclosed, including systems for detection concentrations of industrial and environmentally important gases.
FILED Thursday, July 09, 2020
APPL NO 16/924969
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/42 (20130101)
G01J 2003/423 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/041 (20130101) Original (OR) Class
H01S 5/1838 (20130101)
H01S 5/3218 (20130101)
H01S 5/3403 (20130101)
H01S 5/18358 (20130101)
H01S 5/18361 (20130101)
H01S 5/18366 (20130101)
H01S 5/18377 (20130101)
H01S 5/18383 (20130101)
H01S 5/34306 (20130101)
H01S 5/34366 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11290023 Blasko
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
Creating Innovative and Reliable Circuits Using Inventive Topologies and Semiconductors (ARPAE-CIRCUITS)
APPLICANT(S) Hamilton Sundstrand Corporation (Charlotte, North Carolina)
ASSIGNEE(S) Hamilton Sundstrand Corporation (Charlotte, North Carolina)
INVENTOR(S) Vladimir Blasko (Avon, Connecticut)
ABSTRACT A matrix converter system operating in current control mode is provided. The matrix converter includes a switching matrix coupled between a low voltage side and a high voltage side, wherein the matrix converter is coupled at its low voltage side to a generator for receiving an input power including an input current and transforming the input power into an output power at its high voltage side, wherein a load is coupled to the high voltage side. The control system includes a load observer and a model predictive controller (MPC). The load observer is configured to estimate a load current that flows to the load from the high voltage side of the matrix converter as a function of a switching state of the switching matrix, an output voltage output at the high voltage side of the matrix converter, and the input current. The MPC is configured to select the switching state of the switching matrix to meet one or more control objectives defined by minimization of a multi-objective function that tracks the output voltage and the input current using the estimated load current.
FILED Thursday, April 11, 2019
APPL NO 16/381947
ART UNIT 2839 — Semiconductors/Memory
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 13/048 (20130101)

Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 5/2576 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11290088 Nojima
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Eaton Intelligent Power Limited (Dublin, Ireland)
ASSIGNEE(S) Eaton Intelligent Power Limited (, None)
INVENTOR(S) Geraldo Nojima (Fort Mill, South Carolina)
ABSTRACT An apparatus includes a plurality of parallel-connected semiconductor switches (e.g., silicon carbide (SiC) metal oxide semiconductor field effect transistors (MOSFETs) or other wide-bandgap semiconductor switches) and a plurality of driver circuits having outputs configured to be coupled to control terminals of respective ones of the plurality of semiconductor switches and configured to drive the parallel-connected semiconductor switches responsive to a common switch state control signal. The driver circuits may have respective different power supplies, which may be adjustable. Respective output resistors may couple respective ones of the driver circuits to respective ones of the semiconductor switches. The output resistors may be adjustable.
FILED Wednesday, February 19, 2020
APPL NO 16/795261
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Pulse Technique
H03K 3/011 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11291020 Moradi et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) Hussein Moradi (Idaho Falls, Idaho)
ASSIGNEE(S)
INVENTOR(S) Hussein Moradi (Idaho Falls, Idaho);  Behrouz Farhang (Salt Lake City, Utah)
ABSTRACT Apparatuses, systems and methods are disclosed for wireless communication. A base station may communicate with a plurality of user equipments (UEs) without allocating spectral resources to the UEs for communicating scheduling requests. The base station may detect a scheduling request from a requesting UE of the plurality of UEs. The scheduling request may include a spread spectrum signal based on a spreading sequence. The scheduling request may indicate an identity for a requesting UE without indicating information other than the identity. The base station may grant spectral resources to the requesting UE in response to detecting a scheduling request.
FILED Friday, April 10, 2020
APPL NO 16/846239
ART UNIT 2464 — Multiplex and VoIP
CURRENT CPC
Transmission
H04B 1/69 (20130101)

Wireless Communication Networks
H04W 72/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11291101 Timpson et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Kansas City National Security Campus (KCNSC)
NNSA Critical Mission Site
Operated by Honeywell Federal Manufacturing & Technologies (FM&T) at Kansas City, MO
APPLICANT(S) HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri)
ASSIGNEE(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S) Erik Joseph Timpson (Olathe, Kansas);  Joseph Ambrose Wolf (Olathe, Kansas)
ABSTRACT A system for creating a plasma field Faraday cage around a structure, the system comprising a plurality of lasers spaced apart from each other, each laser being configured to transmit an electromagnetic energy beam to a focal point of an atmosphere region, each electromagnetic energy beam having an amount of energy less than an amount of energy required to ionize air, the electromagnetic energy beams intersecting at the focal point such that the electromagnetic energy beams cooperatively ionize the air at the focal point to block electromagnetic radiation from passing through the focal point.
FILED Monday, August 24, 2020
APPL NO 17/001112
ART UNIT 2881 — Optics
CURRENT CPC
X-ray Technique
H05G 2/008 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11291104 Kroc
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Fermi National Accelerator Laboratory (FNAL)
Federally Funded Research and Development Center (FFRDC)
Operated by Fermi Research Alliance, LLC (FRA) at Batavia, IL
APPLICANT(S) FERMI RESEARCH ALLIANCE, LLC (Batavia, Illinois)
ASSIGNEE(S) FERMI RESEARCH ALLIANCE, LLC (Batavia, Illinois)
INVENTOR(S) Thomas Kroc (Batavia, Illinois)
ABSTRACT A magnetic apparatus and a method of operating the magnetic apparatus can include a scanning electromagnet that redirects a beam of charged particles, a vacuum chamber that prevents the atmosphere from interfering with the charged particles, and, a parallelizing permanent magnet array for parallelizing the beam of charged particles. The parallelizing permanent magnet array can be located proximate to a target comprising a Bremsstrahlung target or an object that is being irradiated. The magnetic field of the scanning electromagnet can be variable to produce all angles necessary to sweep the beam of charged particles across the target and the parallelizing permanent magnet array can be configured from a magnetic material that does not require an electric current.
FILED Wednesday, December 09, 2020
APPL NO 17/116880
ART UNIT 2881 — Optics
CURRENT CPC
Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 7/04 (20130101) Original (OR) Class
H05H 2007/046 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11285607 Rus et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Daniela Rus (Weston, Massachusetts);  Jeffrey Lipton (Medford, Massachusetts);  Aidan Fay (La Jolla, California);  Changhyun Choi (Minneapolis, Minnesota)
ABSTRACT In some aspects, a system comprises a computer hardware processor and a non-transitory computer-readable storage medium storing processor-executable instructions for receiving, from one or more sensors, sensor data relating to a robot; generating, using a statistical model, based on the sensor data, first control information for the robot to accomplish a task; transmitting, to the robot, the first control information for execution of the task; and receiving, from the robot, a result of execution of the task.
FILED Monday, July 15, 2019
APPL NO 16/511492
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/163 (20130101)
B25J 9/1689 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286451 Morgan et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) BROWN UNIVERSITY (Providence, Rhode Island)
ASSIGNEE(S) Brown University (Providence, Rhode Island)
INVENTOR(S) Jeffrey R. Morgan (Sharon, Massachusetts);  Kali L. Manning (Pawtucket, Rhode Island);  Blanche Ip (Providence, Rhode Island)
ABSTRACT The invention provides a device and a method for the assembly of an aggregation of adherent cells, particularly a three-dimensional assembly of adherent cells.
FILED Tuesday, February 05, 2019
APPL NO 16/967182
ART UNIT 1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 23/16 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0068 (20130101)
C12N 2513/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286491 Joshi et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Neel Satish Joshi (Somerville, Massachusetts);  Peter Q. Nguyen (Malden, Massachusetts);  Anna M. Duraj-Thatte (Arlington, Massachusetts);  Pichet Praveschotinunt (Cambridge, Massachusetts)
ABSTRACT Methods of making biofilms having non-native functional polypeptides attached thereto are provided.
FILED Monday, February 10, 2020
APPL NO 16/785874
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/74 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 1/00 (20180101)

Peptides
C07K 14/33 (20130101)
C07K 14/245 (20130101)
C07K 2317/24 (20130101)
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/62 (20130101) Original (OR) Class
C12N 15/70 (20130101)
C12N 2800/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286517 Kishi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Jocelyn Yoshiko Kishi (Boston, Massachusetts);  Thomas E. Schaus (Arlington, Massachusetts);  Peng Yin (Brookline, Massachusetts);  Feng Xuan (Boston, Massachusetts);  Nikhil Gopalkrishnan (Jamaica Plain, Massachusetts);  Sungwook Woo (Chestnut Hill, Massachusetts)
ABSTRACT The present disclosure provides, in some aspects, nucleic acid-based molecular tools that enable the recording of molecular structure and soluble signals as well as the programmed assembly of molecular structures.
FILED Thursday, February 16, 2017
APPL NO 15/999245
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/64 (20130101)
C12N 15/113 (20130101)
C12N 2310/122 (20130101)
C12N 2310/127 (20130101)
C12N 2330/50 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)
C12Q 1/6806 (20130101)
C12Q 1/6809 (20130101)
C12Q 1/6811 (20130101) Original (OR) Class
C12Q 1/6825 (20130101)
C12Q 1/6825 (20130101)
C12Q 1/6853 (20130101)
C12Q 1/6853 (20130101)
C12Q 2525/155 (20130101)
C12Q 2525/155 (20130101)
C12Q 2525/186 (20130101)
C12Q 2525/186 (20130101)
C12Q 2525/204 (20130101)
C12Q 2525/204 (20130101)
C12Q 2525/301 (20130101)
C12Q 2525/301 (20130101)
C12Q 2525/301 (20130101)
C12Q 2531/101 (20130101)
C12Q 2531/101 (20130101)
C12Q 2531/119 (20130101)
C12Q 2531/119 (20130101)
C12Q 2531/119 (20130101)
C12Q 2533/101 (20130101)
C12Q 2533/101 (20130101)
C12Q 2537/16 (20130101)
C12Q 2537/16 (20130101)
C12Q 2537/149 (20130101)
C12Q 2537/149 (20130101)
C12Q 2537/157 (20130101)
C12Q 2537/157 (20130101)
C12Q 2537/163 (20130101)
C12Q 2537/163 (20130101)
C12Q 2537/1373 (20130101)
C12Q 2537/1373 (20130101)
C12Q 2537/1376 (20130101)
C12Q 2537/1376 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286549 Monroe et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) James Alan Monroe (Syracuse, New York);  Jeremy Sean McAllister (New York, New York);  Jay Russell Zgarba (Sugar Land, Texas)
ASSIGNEE(S)
INVENTOR(S) James Alan Monroe (Syracuse, New York);  Jeremy Sean McAllister (New York, New York);  Jay Russell Zgarba (Sugar Land, Texas)
ABSTRACT Systems and methods disclosed herein relate to the manufacture of metallic material with a thermal expansion coefficient in a predetermined range, comprising: deforming, a metallic material comprising a first phase and a first thermal expansion coefficient. In response to the deformation, at least some of the first phase is transformed into a second phase, wherein the second phase comprises martensite, and orienting the metallic material in at least one predetermined orientation, wherein the metallic material, subsequent to deformation, comprises a second thermal expansion coefficient, wherein the second thermal expansion coefficient is within a predetermined range, and wherein the thermal expansion is in at least one predetermined direction. In some embodiments, the metallic material comprises the second phase and is thermo-mechanically deformed to orient the grains in at least one direction.
FILED Monday, February 03, 2020
APPL NO 16/780830
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Alloys
C22C 5/00 (20130101)

Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys
C22F 1/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286551 Rajagopalan et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Jagannathan Rajagopalan (Tempe, Arizona);  Rohit Berlia (Tempe, Arizona)
ABSTRACT In a method of forming a metallic material with a multimodal microstructure, nickel is deposited on a substrate having a patterned surface comprising two materials having differing microstructure. The resulting materials may desirably be utilized in semiconductor devices or microelectromechanical (MEMS) devices.
FILED Monday, October 12, 2020
APPL NO 17/068500
ART UNIT 1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 14/025 (20130101) Original (OR) Class
C23C 14/085 (20130101)
C23C 30/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287627 Preza et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) Chrysanthe Preza (Memphis, Tennessee);  Ana Doblas (Memphis, Tennessee);  Genaro Saavedra-Tortosa (Valencia, Spain);  Manuel Martinez-Corral (Valencia, Spain);  Juan Carlos Barreiro (Valencia, Spain)
ASSIGNEE(S)
INVENTOR(S) Chrysanthe Preza (Memphis, Tennessee);  Ana Doblas (Memphis, Tennessee);  Genaro Saavedra-Tortosa (Valencia, Spain);  Manuel Martinez-Corral (Valencia, Spain);  Juan Carlos Barreiro (Valencia, Spain)
ABSTRACT A multi-focal light-sheet structured illumination system that can be implemented as a part of a commercial fluorescence microscope or a module that is adaptable to fit a number of commercially available microscopes. The system provides simultaneous capture of 2D images from multiple planes within a 3D volume, which are resolved laterally and axially to provide improved resolution along the three dimensions (x,y,z). A Wollaston prism allows several axially-localized high-contrast structure illumination patterns to be generated.
FILED Saturday, June 30, 2018
APPL NO 16/024807
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/0032 (20130101)
G02B 21/0064 (20130101)
G02B 21/0076 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287633 Liu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Congressionally Directed Medical Research Programs (CDMRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Jonathan T. C. Liu (Seattle, Washington);  Lindsey A. Barner (Seattle, Washington);  Adam K. Glaser (Seattle, Washington)
ABSTRACT Apparatuses, systems, and methods for solid immersion meniscus lenses (SIMlenses). An optical system may include a sample holder with a first side which supports a sample, and a second side opposite the first side. The second side of the sample holder may be in contact with an immersion fluid. Light passing between the sample and an objective lens may pass through the sample holder, immersion fluid, and a SIMlens positioned between the immersion fluid and objective. The SIMlens may have a first curved surface and a second curved surface, each of which may be shaped to match a wavefront of the light as it passes through the SIMlens. The immersion fluid, SIMlens, and environment containing the objective may all have different refractive indices.
FILED Wednesday, June 23, 2021
APPL NO 17/356135
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/26 (20130101)
G02B 21/0032 (20130101)
G02B 21/33 (20130101) Original (OR) Class
G02B 21/248 (20130101)
G02B 21/367 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287642 Valentine et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Jason G. Valentine (Nashville, Tennessee);  Cary L. Pint (Nashville, Tennessee);  Zachary J. Coppens (Nashville, Tennessee);  Adam P. Cohn (Nashville, Tennessee)
ABSTRACT A device according to one example of principles described herein may include a backplane, electrochemical actuator, and an optical resonator, wherein the electrochemical actuator is located between the backplane and optical resonator. Applied energy may be used to modify the volume of the electrochemical actuator material modifying the resonant/interferometric absorption, transmission, and reflection at visible and/or infrared frequencies.
FILED Wednesday, September 19, 2018
APPL NO 16/135697
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 26/001 (20130101) Original (OR) Class
G02B 26/085 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/21 (20130101)
G02F 1/0123 (20130101)
G02F 1/155 (20130101)
G02F 1/213 (20210101)
G02F 2001/1536 (20130101)
G02F 2201/083 (20130101)
G02F 2203/02 (20130101)
G02F 2203/15 (20130101)
G02F 2203/055 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287971 Welch et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S) Gregory Welch (Orlando, Florida);  Ryan McMahan (Orlando, Florida);  Gerd Bruder (Orlando, Florida)
ABSTRACT A system for remote tactile telepresence wherein tactile telepresence sessions are time-coded along with audiovisual content wherein playback is heard, seen, and felt. Embodiments associate motion capture with the tactile profile so that remote, haptic recipients may see renderings of objects (e.g., hands) imparting vibrotactile sensations.
FILED Wednesday, July 28, 2021
APPL NO 17/387219
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Electric Digital Data Processing
G06F 3/014 (20130101)
G06F 3/016 (20130101)
G06F 3/04842 (20130101)
G06F 3/04883 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11288261 Gupta et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Social, Behavioral and Economic Sciences (SBE)
Division of Social and Economic Sciences (SES)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Amarnath Gupta (San Diego, California);  Subhasis Dasgupta (San Diego, California);  Margaret Roberts (San Diego, California)
ABSTRACT A method may include determining, based on a data analysis plan that includes analytical operations performed on at least a portion of the dataset being ingested into and/or stored in the polystore, an optimization for the ingestion of the dataset into the polystore. The ingestion of the dataset includes storing, in a first database management system and/or a second database management system in the polystore, the portion of the dataset. The analysis plan may be modified, based on the optimization, by adding, removing, and/or reordering one or more analytical operations included in the data analysis plan. During the ingestion of the dataset, the optimization may be applied by routing, based on the optimization, the portion of the dataset for storage at the first database management system and/or the second database management system. Related systems and articles of manufacture are also provided.
FILED Tuesday, December 04, 2018
APPL NO 16/209397
ART UNIT 2165 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 16/2379 (20190101) Original (OR) Class
G06F 16/24542 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11288379 Mireshghallah et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Fatemehsadat Mireshghallah (La Jolla, California);  Hadi Esmaeilzadeh (La Jolla, California)
ABSTRACT Methods and systems that provide data privacy for implementing a neural network-based inference are described. A method includes injecting stochasticity into the data to produce perturbed data, wherein the injected stochasticity satisfies an ε-differential privacy criterion and transmitting the perturbed data to a neural network or to a partition of the neural network for inference.
FILED Thursday, August 26, 2021
APPL NO 17/458165
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 21/60 (20130101) Original (OR) Class

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/6228 (20130101)
G06K 9/6298 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11288412 Golparvar-Fard et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Mani Golparvar-Fard (Champaign, Illinois);  Derek Hoiem (Champaign, Illinois);  Jacob Je-Chian Lin (Urbana, Illinois);  Kook In Han (Cary, North Carolina);  Joseph M. Degol (Urbana, Illinois)
ABSTRACT A system initializes a set of calibrated images with known 3D pose relative to a 3D building information model (BIM) to be anchor images, detects features within images of unknown position and orientation, and determines matches with features of the calibrated images. The system determines a subset of the images that have at least a threshold number of matching features, selects an image from the subset of the images having the largest number of matching features, and executes a reconstruction algorithm using the image and the anchor images to calibrate the image to the BIM and generate an initial 3D point cloud model. The system repeats the last steps to identify a second image from the subset and perform, starting with the initial 3D point cloud model and using the second image, 3D reconstruction to generate an updated 3D point cloud model that is displayable in a graphical user interface.
FILED Wednesday, April 18, 2018
APPL NO 15/956266
ART UNIT 2148 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 3/04815 (20130101)
G06F 30/13 (20200101) Original (OR) Class

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/0633 (20130101)
G06Q 10/0635 (20130101)
G06Q 10/06313 (20130101)
G06Q 10/06316 (20130101)
G06Q 10/06393 (20130101)
G06Q 50/08 (20130101)

Image Data Processing or Generation, in General
G06T 15/20 (20130101)
G06T 17/05 (20130101)
G06T 19/003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11288815 Qiu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Peng Qiu (Atlanta, Georgia);  Todd Sulchek (Atlanta, Georgia)
ABSTRACT A system for tracking single-cell movement trajectories is disclosed. The system can record, to a plurality of frames, cells (events) within a microfluidic device. Also, the system can identify an event within each frame including whether the event is a single cell or multiple cells. When the event appears differently between frames (e.g., single cell in one frame and multiple cells in another frame), the system can either segment or merge the cell(s). Then, the system can determine a trajectory for the events based on a position of the event in the frames. Further, the system can determine cell properties based on the trajectory of the events.
FILED Monday, January 06, 2020
APPL NO 16/734749
ART UNIT 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00134 (20130101)
G06K 9/00711 (20130101)
G06K 2009/00738 (20130101)

Image Data Processing or Generation, in General
G06T 7/20 (20130101) Original (OR) Class
G06T 2207/30241 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11288818 Daniilidis et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
INVENTOR(S) Konstantinos Daniilidis (Wynnewood, Pennsylvania);  Alex Zihao Zhu (Philadelphia, Pennsylvania)
ABSTRACT A method for prediction of an indication of motion using input from an event-based camera includes receiving events captured by an event-based camera, wherein each of the events represents a location of a change in pixel intensity, a polarity of the change, and a time. The method further includes discretizing the events into time discretized event volumes, each of which contain events that occur within a specified time range. The method further includes providing the time discretized event volumes as input to an encoder-decoder neural network trained to predict an indication of motion using a loss function that measures quality of image deblurring; generating, using the neural network, a prediction of the indication of motion. The method further includes using the prediction of the indication of motion in a machine vision application.
FILED Wednesday, February 19, 2020
APPL NO 16/795079
ART UNIT 2637 — Optical Communications
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/0472 (20130101)

Image Data Processing or Generation, in General
G06T 7/246 (20170101) Original (OR) Class
G06T 2207/20084 (20130101)
G06T 2207/30252 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11289299 Williams
FUNDED BY
National Science Foundation (NSF)
Directorate of Geosciences (GEO)
Division of Earth Sciences (EAR)
APPLICANT(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S) Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Peter Williams (Phoenix, Arizona)
ABSTRACT A duoplasmatron ion source with a partially ferromagnetic anode can be used in multiple applications, including the production of negative ions for secondary ion mass spectrometers and particle accelerators. A partially ferromagnetic anode, which may be embodied in a partially ferromagnetic anode insert, includes a ferromagnetic and non-ferromagnetic portions joined together at a juncture, with an ion extraction aperture defined in the ferromagnetic portion and the juncture being laterally offset from the aperture. An asymmetric magnetic field produced by the partially ferromagnetic region facilitates extraction of charged ions from the central, most intense region of a source plasma in the duoplasmatron ion source. A ferromagnetic conical portion of the anode defines the ion extraction aperture in order to maximize the magnetic field in the vicinity of this aperture.
FILED Friday, October 23, 2020
APPL NO 16/972384
ART UNIT 2879 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 9/14 (20130101)
H01J 27/10 (20130101) Original (OR) Class
H01J 49/123 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11289321 Cooks et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Robert Graham Cooks (West Lafayette, Indiana);  Jason Duncan (Dayton, Indiana);  Joshua Wiley (Lafayette, Indiana)
ABSTRACT The invention generally relates to ion traps and methods of use thereof. In certain embodiments, the invention provides a system that includes a mass spectrometer including an ion trap, and a central processing unit (CPU). The CPU has storage that is coupled to the CPU for storing instructions that when executed by the CPU cause the system to apply a constant radio frequency (RF) signal to the ion trap, and apply a first alternating current (AC) signal to the ion trap the frequency of which varies as a function of time.
FILED Wednesday, October 14, 2020
APPL NO 17/070411
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 49/0031 (20130101)
H01J 49/422 (20130101)
H01J 49/426 (20130101) Original (OR) Class
H01J 49/427 (20130101)
H01J 49/4285 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11289386 Basol et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology
Translational Impacts (TI)
APPLICANT(S) Active Layer Parametrics, Inc. (Scotts Valley, California)
ASSIGNEE(S) Active Layer Parametrics, Inc. (Scotts Valley, California)
INVENTOR(S) Bulent Mehmet Basol (Manhattan Beach, California);  Jalal Ashjaee (Cupertino, California);  Abhijeet Joshi (San Jose, California)
ABSTRACT A method for electrically characterizing a layer disposed on a substrate and electrically insulated from the substrate is disclosed. The method can include forming a test pattern, contacting the test pattern with electrical contact elements at contact regions, and measuring an electrical parameter of the layer by passing a first set of test currents between contact regions. The test pattern can be formed by pushing a pattern forming head against a top surface of the layer, introducing a first fluid into the cavity, and converting the sacrificial portion of the layer into an insulator using the first fluid and forming the test pattern under the test-pattern-shaped inner seal.
FILED Monday, March 16, 2020
APPL NO 16/820447
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/2644 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/326 (20130101)
H01L 21/02318 (20130101)
H01L 21/6715 (20130101)
H01L 22/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11289729 Nuckolls et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Colin Nuckolls (New York, New York);  Raul Hernandez Sanchez (New York, New York);  Yuan Yang (New York, New York);  Thomas Sisto (New York, New York);  Margarita Milton (New York, New York)
ABSTRACT The present disclosure relates to organic electrolyte solutions including organic electrolytes (e.g., aromatic imides, ferrocenes, spiro fused compounds, or cyclopropenium compounds), and redox flow batteries and systems including the same.
FILED Monday, February 17, 2020
APPL NO 16/792501
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 8/20 (20130101) Original (OR) Class
H01M 8/2435 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11289879 Yun
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
INVENTOR(S) Seok Hyun Yun (Belmont, Massachusetts)
ABSTRACT Disclosed are photonic particles and methods of using particles in biological samples. The particles are configured to emit laser light when energetically stimulated by, e.g., a pump source. The particles may include a gain medium with inorganic materials, an optical cavity with high refractive index, and a coating with organic materials. The particles may be smaller than 3 microns along their longest axes. The particles may attach to each other to form, e.g., doublets and triplets. The particles may be injection-locked by coupling an injection beam into a particle while pumping so that an injection seed is amplified to develop into laser oscillation. A microscopy system may include a pump source, beam scanner, spectrometer with resolution of less than 1 nanometer and acquisition rate of more than 1 kilohertz, and spectral analyzer configured to distinguish spectral peaks of laser output from broadband background.
FILED Monday, June 08, 2020
APPL NO 16/895914
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 2003/2826 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/648 (20130101)
G01N 2015/1006 (20130101)
G01N 2021/6439 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/091 (20130101)
H01S 3/169 (20130101)
H01S 3/213 (20130101)
H01S 3/0604 (20130101)
H01S 5/36 (20130101)
H01S 5/40 (20130101)
H01S 5/041 (20130101)
H01S 5/1025 (20130101)
H01S 5/1067 (20130101) Original (OR) Class
H01S 5/1075 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11285154 Habib
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Neurological Disorders and Stroke (NINDS)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) United States Government as Represented by The Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S) Amyn Aziz Habib (Dallas, Texas)
ABSTRACT Provided herein are methods and pharmaceutical compositions for treating cancer, in a patient in need thereof, said method comprising administering to said patient an effective amount of an EGFR inhibitor and a TNF inhibitor.
FILED Thursday, March 29, 2018
APPL NO 15/940802
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/17 (20130101)
A61K 31/17 (20130101)
A61K 31/277 (20130101)
A61K 31/277 (20130101)
A61K 31/416 (20130101)
A61K 31/416 (20130101)
A61K 31/454 (20130101)
A61K 31/454 (20130101)
A61K 31/498 (20130101)
A61K 31/498 (20130101)
A61K 31/502 (20130101)
A61K 31/502 (20130101)
A61K 31/517 (20130101) Original (OR) Class
A61K 31/517 (20130101)
A61K 31/573 (20130101)
A61K 31/713 (20130101)
A61K 31/713 (20130101)
A61K 31/4178 (20130101)
A61K 31/4178 (20130101)
A61K 31/4439 (20130101)
A61K 31/4439 (20130101)
A61K 31/4985 (20130101)
A61K 31/4985 (20130101)
A61K 38/1793 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/241 (20130101)
C07K 2317/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285293 Tang et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) The University of Maryland, Baltimore (Baltimore, Maryland);  The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) University Of Maryland, Baltimore (Baltimore, Maryland);  THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S) Cha-Min Tang (Wayne, Pennsylvania);  Paul E. Bigeleisen (Baltimore, Maryland);  Samuel M. Galvagno, Jr. (Baltimore, Maryland);  Mark E. Shirtliff (Ellicott City, Maryland)
ABSTRACT A device disclosed herein includes a tubular member which is flexible and configured to receive ultraviolet (UV) light from a UV illumination coupler. The tubular member contains a lumen defining a longitudinal interior space within the tubular member, a tubular body bounded by an inner wall defining an outer boundary of the lumen and an outer wall defining an outer surface of the tubular member, at least one optical fiber disposed outside of the interior space not parallel to an axis of the lumen and adapted to receive the UV light from the UV illumination coupler, and a protective component adapted to prevent substantively all of the UV light emitted from the optical fiber from exiting the outer wall. Methods for producing and using such devices are also disclosed herein.
FILED Tuesday, December 11, 2018
APPL NO 16/216076
ART UNIT 3781 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 29/06 (20130101)
A61L 29/06 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 25/04 (20130101)
A61M 25/0012 (20130101)
A61M 25/0017 (20130101)
A61M 25/0043 (20130101) Original (OR) Class
A61M 25/0045 (20130101)
A61M 27/00 (20130101)
A61M 2025/0056 (20130101)
A61M 2202/0496 (20130101)
A61M 2205/587 (20130101)

Compositions of Macromolecular Compounds
C08L 83/04 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49016 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285321 Ganguly et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) The Regents of the University of California (Oakland, California);  U.S. Government Represented by the Department of Veterans Affairs (Washington, District of Columbia);  LightSide MD, LLC (Los Altos, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  U.S. Government Represented by the Department of Veterans Affairs (Washington, District of Columbia);  LightSide MD, LLC (Los Altos, California)
INVENTOR(S) Karunesh Ganguly (San Francisco, California);  Adelyn Tsu (San Francisco, California);  Nikhilesh Natraj (San Francisco, California);  Gabriel Philip Howles-Banerji (Oakland, California);  Rajiv Doshi (Los Altos, California);  Kondapavulur T. Venkateswara-Rao (San Jose, California)
ABSTRACT Methods and apparatuses for sensory electrical stimulation of the peripheral nervous system to improve human motor function and performance are described. Methods and devices may be used to enhance physical performance of athletes, professionals, and gamers or improve motor function (hand, finger and limb movement) in patients rehabilitating from neurological deficits and impairments caused by stroke, traumatic brain injury and other neurologic or non-neurologic conditions. These apparatuses and methods may be used for physical training and mental training (to improve memory and functional performance including motor coordination, limb-eye coordination, occupational and recreational skills) through periodic or sustained sensory electrical stimulation. Treatment plans may be based on biomarkers and may be used alone or in combination with other apparatuses. Learning and feedback techniques individualize treatment parameters depending on the subject's neurologic and motor function in diseased patients and healthy users.
FILED Tuesday, November 14, 2017
APPL NO 16/461085
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/002 (20130101)
A61B 5/30 (20210101)
A61B 5/375 (20210101)
A61B 5/4047 (20130101)
A61B 5/4824 (20130101)
A61B 5/4848 (20130101)
A61B 5/7275 (20130101)
A61B 5/7455 (20130101)
A61B 2505/09 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/378 (20130101)
A61N 1/0456 (20130101)
A61N 1/0484 (20130101)
A61N 1/0492 (20130101)
A61N 1/36021 (20130101)
A61N 1/36031 (20170801) Original (OR) Class
A61N 1/36034 (20170801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286251 Sadeghi et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Yale University (New Haven, Connecticut);  The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) YALE UNIVERSITY (New Haven, Connecticut);  THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S) Mehran Sadeghi (Bethany, Connecticut);  Yunpeng Ye (Staten Island, New York);  Hye-Yeong Kim (Hamden, Connecticut);  Henry(Yiyun) Huang (Madison, Connecticut);  Jakub Toczek (New Haven, Connecticut)
ABSTRACT The present invention provides certain compounds, or salts or solvates thereof, which can be used as matrix metalloproteinase-targeted inhibitors or imaging agents.
FILED Friday, April 07, 2017
APPL NO 16/088868
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 51/044 (20130101)

Heterocyclic Compounds
C07D 273/01 (20130101)
C07D 413/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286525 Tsalik et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Veterans Affairs (DVA)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina);  United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Ephraim L. Tsalik (Cary, North Carolina);  Geoffrey S. Ginsburg (Durham, North Carolina);  Christopher W. Woods (Durham, North Carolina);  Ricardo Henao Giraldo (Durham, North Carolina);  Rachel A. Myers (Raleigh, North Carolina)
ABSTRACT The present disclosure provides methods for determining whether a subject has sepsis, or is at risk of developing sepsis, and methods of treating the subject based on the determination. Also provided are methods for determining an increased risk of mortality in a subject with sepsis or suspected of having sepsis, and methods of treating the subject based on the determination. Systems useful for the same are also provided.
FILED Tuesday, January 16, 2018
APPL NO 16/478202
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6876 (20130101) Original (OR) Class
C12Q 2600/118 (20130101)
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287427 Powers et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) VANDERBILT UNIVERSITY (Nashville, Tennessee);  THE UNITED STATES AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
ASSIGNEE(S) VANDERBILT UNIVERSITY (Nashville, Tennessee);  THE UNITED STATES AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S) Alvin C. Powers (Brentwood, Tennessee);  Marcela Brissova (Nashville, Tennessee);  Chunhua Dai (Nashville, Tennessee);  Neil Phillips (Lawrenceville, Georgia);  Diane Saunders (Nashville, Tennessee)
ABSTRACT In spite of significant efforts to identify β-cell-specific markers for β-cell imaging and purification, progress has been limited. Herein is disclosed a novel biomarker of human pancreatic β-cells, CD39L3 (also known as ectonucleoside triphosphate diphosphohydrolase-3 (NTPDase3)). Disclosed are compositions and methods for purifying and imaging β-cell using anti-CD39L3 antibodies.
FILED Monday, June 11, 2018
APPL NO 16/620747
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/39 (20130101)

Peptides
C07K 16/40 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/573 (20130101)
G01N 33/54313 (20130101)
G01N 33/54326 (20130101)
G01N 33/56966 (20130101) Original (OR) Class
G01N 2500/10 (20130101)
G01N 2800/042 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11285039 Steele et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Johnson Space Center (JSC)
APPLICANT(S) Hamilton Sundstrand Corporation (Charlotte, North Carolina)
ASSIGNEE(S) HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina)
INVENTOR(S) John W. Steele (New Hartford, Connecticut);  Peter A. Canga (League City, Texas);  Barbara M. Peyton (Windsor, Connecticut);  Tony Rector (East Granby, Connecticut);  Douglas Zupan (La Porte, Texas)
ABSTRACT A thermal management system includes a space structure, a feed water container, a water feed line, a pump, and a filter device. The space structure includes a heat source connected with a fluid loop for conveying a working fluid through the heat source to regulate temperature and a sublimator connected with the fluid loop to receive the working fluid. The sublimator has a porous surface. The water feed line is connected with the container and the sublimator. The pump is located in the feed water line and is operable to move the feed water from the container to the sublimator. The sublimator is operable to cool the working fluid using the porous surface. The filter device is located in the water feed line between the pump and the feed water container. The filter device includes an adsorbent bed to remove organic compounds.
FILED Tuesday, May 15, 2018
APPL NO 15/979673
ART UNIT 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 7/0085 (20130101) Original (OR) Class
A61F 2007/0056 (20130101)

Separation
B01D 7/00 (20130101)

Cosmonautics; Vehicles or Equipment Therefor
B64G 6/00 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/001 (20130101)
C02F 1/50 (20130101)
C02F 1/283 (20130101)
C02F 9/005 (20130101)
C02F 2101/34 (20130101)
C02F 2101/40 (20130101)
C02F 2101/322 (20130101)
C02F 2103/023 (20130101)
C02F 2303/04 (20130101)

Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening
F24F 5/0035 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285154 Habib
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Neurological Disorders and Stroke (NINDS)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) United States Government as Represented by The Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S) Amyn Aziz Habib (Dallas, Texas)
ABSTRACT Provided herein are methods and pharmaceutical compositions for treating cancer, in a patient in need thereof, said method comprising administering to said patient an effective amount of an EGFR inhibitor and a TNF inhibitor.
FILED Thursday, March 29, 2018
APPL NO 15/940802
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/17 (20130101)
A61K 31/17 (20130101)
A61K 31/277 (20130101)
A61K 31/277 (20130101)
A61K 31/416 (20130101)
A61K 31/416 (20130101)
A61K 31/454 (20130101)
A61K 31/454 (20130101)
A61K 31/498 (20130101)
A61K 31/498 (20130101)
A61K 31/502 (20130101)
A61K 31/502 (20130101)
A61K 31/517 (20130101) Original (OR) Class
A61K 31/517 (20130101)
A61K 31/573 (20130101)
A61K 31/713 (20130101)
A61K 31/713 (20130101)
A61K 31/4178 (20130101)
A61K 31/4178 (20130101)
A61K 31/4439 (20130101)
A61K 31/4439 (20130101)
A61K 31/4985 (20130101)
A61K 31/4985 (20130101)
A61K 38/1793 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/241 (20130101)
C07K 2317/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286042 Calkins et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Glenn Research Center (GLENN)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Frederick Theodore Calkins (Renton, Washington);  Douglas E. Nicholson (Saint Charles, Missouri);  Jordan Kreitzman (Saint Charles, Missouri)
ABSTRACT Variably porous panels and panel assemblies incorporating shape memory alloy components along with methods for actuating the shape memory alloys are disclosed to predictably alter the porosity of a substrate surface, with the shape memory alloy maintained in an orientation relative to the panel that is in-plane with a mold-line of the panel outer surface.
FILED Friday, August 10, 2018
APPL NO 16/100412
ART UNIT 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 61/06 (20130101)

Aeroplanes; Helicopters
B64C 21/02 (20130101)
B64C 21/08 (20130101) Original (OR) Class
B64C 21/025 (20130101)
B64C 2230/20 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 2033/0206 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286067 Weathers et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Marshall Space Flight Center (MSFC)
APPLICANT(S) THE BOEING COMPANY (Chicago, Illinois)
ASSIGNEE(S) THE BOEING COMPANY (Chicago, Illinois)
INVENTOR(S) Jeffrey W. Weathers (Huntsville, Alabama);  Dustin Gregory Padgett (Huntsville, Alabama)
ABSTRACT A system includes a first component, a second component, a locking pin, and an interface assembly that is configured to selectively adjust a stiffness of a coupling interface between the first component and the second component. The interface assembly includes at least one support coupler secured to the first component. The support coupler(s) includes a main body, a first arm extending from a first side of the main body, a second arm extending from a second side of the main body, and a flange extending from the main body. The flange includes a locking pin hole that is configured to selectively receive the locking pin. The locking pin is selectively moveable between a retracted position in which the locking pin is out of the locking pin hole, and a deployed position in which the locking pin extends into the locking pin hole and a portion of the first component and locks the interface assembly to the first component.
FILED Tuesday, October 09, 2018
APPL NO 16/154832
ART UNIT 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/641 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286865 Klein et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Glenn Research Center (GLENN)
APPLICANT(S) Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana)
ASSIGNEE(S) Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana)
INVENTOR(S) Kyle Klein (Indianapolis, Indiana);  Michael Karam (Plainfield, Indiana);  Jonathan Sands (Clayton, Indiana)
ABSTRACT A gas turbine engine includes a fan and an engine core that includes a compressor, a combustor, and a turbine. The fan and the compressor include variable pitch geometry. The gas turbine engine further includes a control system configured to adjust the variable pitch geometry of the fan and the compressor to optimize a performance characteristic of the gas turbine engine.
FILED Friday, September 14, 2018
APPL NO 16/131729
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 9/20 (20130101) Original (OR) Class

Jet-propulsion Plants
F02K 1/66 (20130101)
F02K 3/06 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/323 (20130101)
F05D 2270/05 (20130101)
F05D 2270/07 (20130101)
F05D 2270/08 (20130101)
F05D 2270/101 (20130101)
F05D 2270/112 (20130101)
F05D 2270/333 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11289789 Bulcha
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Berhanu T. Bulcha (Bowie, Maryland)
ABSTRACT A six-pole patch bandpass filter includes a dielectric substrate and six electrically-conductive isosceles-triangle patches disposed thereon. A first pair of the patches is an electrically connected pair. The first pair of patches is capacitively coupled to a first microstrip. A second pair of the patches is also an electrically connected pair. The second pair of patches is capacitively coupled to a second microstrip. A third pair of the patches are nested between and capacitively coupled to the first pair of patches and the second pair of patches.
FILED Monday, May 03, 2021
APPL NO 17/306552
ART UNIT 2843 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 1/203 (20130101)
H01P 1/20309 (20130101)
H01P 1/20381 (20130101)
H01P 7/088 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 11287334 Eckel et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland);  NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Gaithersburg, Maryland)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland);  Government of the USA, as represented by the Secretary of Commerce, National Institute of Standards and Technology (Gaithersburg, Maryland)
INVENTOR(S) Stephen Eckel (Rockville, Maryland);  James Fedchak (Washington, District of Columbia);  Thomas Purdy (Gaithersburg, Maryland);  Robinjeet Singh (Gaithersburg, Maryland)
ABSTRACT An optomechanical pressure-measurement system measures pressure in the range of 10−6 Pa-10−2 Pa by measuring various properties of a vibrational mode of an ultra-thin membrane member. With independent measurements of the thickness and density of the membrane, in addition to the measured vibration mode properties, the system can operate as a primary pressure sensor. The membrane member is mounted on a vibration-isolated mount and is excited by a drive force. A laser beam impinges on the excited membrane, and an optical phase detector detects the amplitude of the oscillations, as well as parameters of the laser beam affected by the membrane vibration. In one embodiment, a mechanical damping is computed based on the amplitude or frequency shift (depending on the pressure range), and the pressure based on the ring-down time of the membrane vibration mode.
FILED Wednesday, June 19, 2019
APPL NO 16/445583
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/103 (20130101) Original (OR) Class
G01L 1/106 (20130101)
G01L 27/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11287366 Long et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S) GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S) Christian John Long (Westminster, Colorado);  Nathan Daniel Orloff (Louisville, Colorado);  Nina Popovic Basta (Boulder, Colorado);  Edward Joseph Garboczi (Arvada, Colorado)
ABSTRACT A scanning microwave ellipsometer includes: a microwave ellipsometry test head including: a polarization controller; a transmission line; and a sensor that produces sensor microwave radiation, subjects a sample to the sensor microwave radiation, receives a sample reflected microwave radiation from the sample that results from subjecting the sample with the sample reflected microwave radiation, and produces a sensor-received microwave radiation from the sample reflected microwave radiation, wherein a polarization of the sensor microwave radiation is controlled by the polarization controller; an electrical signal measurement system that produces an electrical readout signal such that a magnitude of reflection coefficient Γ and an angle of reflection coefficient Γ of the sample reflected microwave radiation is determined from the electrical readout signal; and a position controller that adjusts a relative position of the sensor and the sample.
FILED Friday, May 01, 2020
APPL NO 16/864466
ART UNIT 2886 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/211 (20130101) Original (OR) Class
G01N 22/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11291103 Eckel et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S) GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S) Stephen Paul Eckel (Rockville, Maryland);  Daniel Schaeder Barker (Berwyn Heights, Maryland);  James Anthony Fedchak (Washington, District of Columbia);  Julia Kay Scherschligt (Montgomery Village, Maryland);  Eric Burton Norrgard (Silver Spring, Maryland);  Nikolai Nikolaevich Klimov (Ellicott City, Maryland)
ABSTRACT A uniaxial counter-propagating monolaser atom trap cools and traps atoms with a single a laser beam and includes: an atom slower that slows atoms to form slowed atoms; an optical diffractor including: a first diffraction grating that receives primary light and produces first reflected light; a second diffraction grating that receives primary light and produces second reflected light; and a third diffraction grating that receives the primary light and produces third reflected light; and a trapping region that forms trap light from the reflected lights and receives slowed atoms to produce trapped atoms from the slowed atoms that interact with the trap light.
FILED Thursday, October 10, 2019
APPL NO 16/598144
ART UNIT 2881 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 27/42 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 37/08 (20130101)
H01J 37/075 (20130101)
H01J 2237/0815 (20130101)

Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 3/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11285478 Hung et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Combinati Incorporated (Palo Alto, California)
ASSIGNEE(S) Combinati Incorporated (Carlsbad, California)
INVENTOR(S) Ju-Sung Hung (Palo Alto, California);  Andrew Zayac (San Leandro, California);  Megan Dueck (Brisbane, California)
ABSTRACT In some aspects, the present disclose provides methods for amplifying and quantifying nucleic acids. Methods for amplifying and quantifying nucleic acids comprise isolating a sample comprising nucleic acid molecules into a plurality of microchambers, performing a polymerase chain reaction on the plurality of microchambers, and analyzing the results of the polymerase chain reaction. In some aspects, the present disclosure provides devices consistent with the methods herein.
FILED Friday, October 13, 2017
APPL NO 15/783743
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/50273 (20130101) Original (OR) Class
B01L 7/52 (20130101)
B01L 2200/0605 (20130101)
B01L 2300/18 (20130101)
B01L 2300/0609 (20130101)
B01L 2300/0851 (20130101)
B01L 2300/0864 (20130101)
B01L 2400/049 (20130101)
B01L 2400/0487 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/686 (20130101)
C12Q 2563/159 (20130101)
C12Q 2565/629 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11285616 Penning et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Oklahoma City Air Logistics Complex (OC-ALC)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Teradyne, Inc. (North Reading, Massachusetts)
ASSIGNEE(S) Teradyne, Inc. (North Reading, Massachusetts)
INVENTOR(S) Ryan S. Penning (Madison, Wisconsin);  Ralph F. Polimeni, Jr. (Reno, Nevada);  Brett L. Limone (Danvers, Massachusetts);  James D. English (Alva, Florida)
ABSTRACT The specification and drawings present a robotic coating application system and a method for coating at least one part with a robotic coating application system. The robotic coating application system may comprise an enclosure configured to receive at least one part. The robotic coating application system may further comprise at least one robot configured to operate at least partially within the enclosure. The robotic coating application system may also comprise a graphical user interface to display a model of the at least one part and allow a user to select a portion or subportion of the model for application of a coating. The coating may be automatically applied to the at least one part based upon, at least in part, the user-selected portion or subportion.
FILED Tuesday, September 11, 2018
APPL NO 16/127960
ART UNIT 1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Spraying Apparatus; Atomising Apparatus; Nozzles
B05B 13/0431 (20130101)

Apparatus for Applying Fluent Materials to Surfaces, in General
B05C 5/0212 (20130101)
B05C 5/0216 (20130101)
B05C 9/10 (20130101)
B05C 13/02 (20130101)
B05C 15/00 (20130101)

Manipulators; Chambers Provided With Manipulation Devices
B25J 9/0081 (20130101)
B25J 9/163 (20130101)
B25J 11/0075 (20130101) Original (OR) Class
B25J 13/06 (20130101)
B25J 13/081 (20130101)
B25J 15/0066 (20130101)
B25J 19/022 (20130101)
B25J 19/023 (20130101)

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/042 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11286256 Fuller et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Alkermes, Inc. (Waltham, Massachusetts)
ASSIGNEE(S) Alkermes, Inc. (Waltham, Massachusetts)
INVENTOR(S) Nathan Oliver Fuller (Arlington, Massachusetts);  John A. Lowe, III (Stonington, Connecticut)
ABSTRACT Provided herein are compounds and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of conditions associated with inhibition of HDAC (e.g,. HDAC2).
FILED Thursday, May 21, 2020
APPL NO 16/880075
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/437 (20130101)
A61K 31/519 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/28 (20180101)

Heterocyclic Compounds
C07D 471/04 (20130101) Original (OR) Class
C07D 487/04 (20130101)
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Department of Agriculture (USDA) 

US 11286464 Ramamoorthy
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) NDSU Research Foundation (Fargo, North Dakota)
ASSIGNEE(S) NDSU RESEARCH FOUNDATION (Fargo, North Dakota)
INVENTOR(S) Sheela Ramamoorthy (Fargo, North Dakota)
ABSTRACT Provided herein is a method for producing an inactivated virus including a) heating the virus to a temperature sufficient to disrupt the virus membrane; b) exposing the virus of step (a) to an RNA degrading enzyme; and c) cooling the virus to a temperature sufficient to reestablish the integrity of the virus membrane. Also provided herein is a vaccine produced using the instant method.
FILED Tuesday, February 27, 2018
APPL NO 15/906685
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/145 (20130101)
A61K 39/215 (20130101)
A61K 2039/543 (20130101)
A61K 2039/5252 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)
A61P 31/16 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101) Original (OR) Class
C12N 2760/16134 (20130101)
C12N 2760/16163 (20130101)
C12N 2770/20034 (20130101)
C12N 2770/20063 (20130101)
C12N 2770/24134 (20130101)
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