FedInvent™ Patents

Patent Details for Tuesday, April 12, 2022 

This page was updated on Thursday, April 14, 2022 at 04:54 PM GMT

Department of Health and Human Services (HHS) 

US 11298018 Dana et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Massachusetts Eye and Ear Infirmary (Boston, Massachusetts)
ASSIGNEE(S) Massachusetts Eye and Ear Infirmary (Boston, Massachusetts)
INVENTOR(S) Reza Dana (Newton, Massachusetts);  Francisco L. Amparo Pulido (Cambridge, Massachusetts);  Haobing Wang (Newton, Massachusetts)
ABSTRACT The present application includes methods, systems and computer readable storage devices for determining a color score for at least a portion of a biological tissue. The subject matter of the application is embodied in a method that includes obtaining a digital image of the biological tissue, and receiving a selection of a portion of the image as an evaluation area. The method also includes determining for each of a plurality of pixels within the evaluation area, a plurality of color components that are based on a Cartesian color space, and determining, from the color components, a hue value in a polar coordinate based color space. The method further includes determining a color value based on the hue value for each of the plurality of pixels, and assigning a color score to the evaluation area based on an average of the color values of the plurality of pixels.
FILED Wednesday, December 18, 2019
APPL NO 16/719321
ART UNIT 3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/14 (20130101) Original (OR) Class
A61B 3/0016 (20130101)
A61B 5/103 (20130101)
A61B 5/1032 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 7/90 (20170101)
G06T 2207/30041 (20130101)

Pictorial Communication, e.g Television
H04N 1/628 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298041 Bankiewicz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of California (Oakland, California);  Voyager Therapeutics, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  Voyager Therapeutics, Inc. (Cambridge, Massachusetts)
INVENTOR(S) Krystof S. Bankiewicz (Oakland, California);  Kathryn H. Rosenbluth (San Francisco, California);  Adrian P. Kells (San Francisco, California)
ABSTRACT The present disclosure provides methods for targeting a biomedical system. Aspects of the subject methods include determining the trajectory of a targeting device using magnetic resonance imaging (MRI) of a MRI-visible style of a trajectory guide that is compatible with the targeting device. Targeted biomedical systems may be utilized for a variety of purposes including targeted delivery of a therapeutic, holding a therapeutic device, positioning of a therapeutic device and other uses. Also provided are devices and systems that can be used in practicing the described methods including but not limited to trajectory guides and adjustable targeting systems, as well as non-transitory computer readable medium storing instructions that, when executed by a computing device, cause a computing device to perform steps of the described methods.
FILED Tuesday, August 29, 2017
APPL NO 16/328940
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101) Original (OR) Class
A61B 5/1071 (20130101)
A61B 5/1072 (20130101)
A61B 5/1127 (20130101)
A61B 5/6835 (20130101)
A61B 6/03 (20130101)
A61B 6/04 (20130101)
A61B 34/10 (20160201)
A61B 90/11 (20160201)
A61B 2017/00911 (20130101)
A61B 2034/107 (20160201)
A61B 2505/05 (20130101)
A61B 2560/0475 (20130101)
A61B 2576/026 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298043 Bankiewicz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Krystof S. Bankiewicz (Oakland, California);  Kathryn H. Rosenbluth (San Francisco, California);  Adrian P. Kells (San Francisco, California)
ABSTRACT The present disclosure provides methods for targeting a biomedical system. Aspects of the subject methods include determining the trajectory of a targeting device using magnetic resonance imaging (MRI) of a MRI-visible style of a trajectory guide that is compatible with the targeting device. Targeted biomedical systems may be utilized for a variety of purposes including targeted delivery of a therapeutic, holding a therapeutic device, positioning of a therapeutic device and other uses. Also provided are devices and systems that can be used in practicing the described methods including but not limited to trajectory guides and adjustable targeting systems, as well as non-transitory computer readable medium storing instructions that, when executed by a computing device, cause a computing device to perform steps of the described methods.
FILED Thursday, September 05, 2019
APPL NO 16/562260
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101) Original (OR) Class
A61B 5/1071 (20130101)
A61B 5/1072 (20130101)
A61B 5/1127 (20130101)
A61B 5/6835 (20130101)
A61B 6/03 (20130101)
A61B 6/04 (20130101)
A61B 34/10 (20160201)
A61B 90/11 (20160201)
A61B 2017/00911 (20130101)
A61B 2034/107 (20160201)
A61B 2505/05 (20130101)
A61B 2560/0475 (20130101)
A61B 2576/026 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298137 Shabaz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Inceptus Medical LLC (Aliso Viejo, California)
ASSIGNEE(S) INCEPTUS MEDICAL LLC (Aliso Viejo, California)
INVENTOR(S) Martin Shabaz (Aliso Viejo, California);  Claudio Plaza (Irvine, California);  Richard Quick (Mission Viejo, California);  Paul Lubock (Monarch Beach, California);  Brian J. Cox (Laguna Niguel, California)
ABSTRACT In a system and method for deployment of an implant device, the implant device includes a first loop at its proximal end, and a deployment tool has a second loop attached at its distal end. A release wire slidably disposed within the deployment tool has a distal end extending through the first and second loops to releasably couple the implant device to the deployment tool, and a proximal portion extending from a proximal end of the deployment tool, which is held in a retraction device. The retraction device is operable to hold the proximal end of the deployment tool and to pull the release wire proximally through the deployment tool until the distal end of the release wire is withdrawn from the first and second loops to decouple the implant device from the deployment tool.
FILED Friday, January 10, 2020
APPL NO 16/739550
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/12109 (20130101) Original (OR) Class
A61B 2017/00367 (20130101)
A61B 2017/00477 (20130101)
A61B 2017/00526 (20130101)
A61B 2017/00575 (20130101)
A61B 2017/00592 (20130101)
A61B 2017/00623 (20130101)
A61B 2017/12054 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298205 Krishnaswamy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CairnSurgical, Inc. (Lebanon, New Hampshire)
ASSIGNEE(S) CairnSurgical, Inc. (Lebanon, New Hampshire)
INVENTOR(S) Venkataramanan Krishnaswamy (Lebanon, New Hampshire);  Robert F. Rioux (Ashland, Massachusetts);  David Danielsen (Westborough, Massachusetts);  George Bourne (Boston, Massachusetts)
ABSTRACT The present disclosure includes customized guidance devices in the form of guidance templates configured to fit over a given area of a patient's body and provide guidance during a tissue treatment or tissue removal procedure of that given area, which may include administration of an agent to a target tissue, target tissue biopsy, target tissue resection, or target tissue ablation. The customized guidance templates are generally constructed via an additive manufacturing process (i.e., three-dimensional (3D) printing) or subtractive manufacturing process (i.e., milling) based on a fabrication instruction file, which may include imaging data of the given area of the patient's body in which targeted tissue treatment is to be performed. The fabrication instruction file may further include additional data, such as the type of procedure to be performed (i.e., biopsy of the tissue abnormality, destruction or resection of the tissue abnormality, etc.).
FILED Thursday, December 19, 2019
APPL NO 16/721493
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 10/0233 (20130101)
A61B 17/3403 (20130101)
A61B 34/20 (20160201)
A61B 90/17 (20160201) Original (OR) Class
A61B 2017/00796 (20130101)
A61B 2017/3405 (20130101)
A61B 2034/107 (20160201)
A61B 2090/3908 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298231 Bachus et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) University of Utah Research Foundation (Salt Lake City, Utah);  Joseph A. Longo (Paradise Valley, Arizona)
ASSIGNEE(S) Joseph A. Longo (Paradise Valley, Arizona);  UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah)
INVENTOR(S) Kent N. Bachus (Salt Lake City, Utah);  Sujee Jeyapalina (Salt Lake City, Utah);  James Peter Beck (Salt Lake City, Utah);  Roy Bloebaum (Salt Lake City, Utah);  Jayant P. Agarwal (Salt Lake City, Utah);  Joseph A. Longo (Paradise Valley, Arizona);  Erik Kubiak (Salt Lake City, Utah);  Brian Mueller Holt (Topanga, California)
ABSTRACT An implant assembly for a long bone is adapted to support an exo-prosthesis. The assembly includes a stem, a subdermal component and a percutaneous post. The stem has a proximal end that is adapted to be received in a surgically prepared medullary canal of the long bone, and a distal end having a surface that is adapted to promote bone ingrowth. The subdermal component includes a proximal portion that is adapted for attachment to the distal end of the stem, and a fixation surface that is adapted to promote soft tissue fixation. The percutaneous post has a proximal end that is adapted to be attached to the subdermal component.
FILED Friday, April 12, 2019
APPL NO 16/383363
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/78 (20130101)
A61F 2/2814 (20130101) Original (OR) Class
A61F 2002/7887 (20130101)
A61F 2002/30576 (20130101)
A61F 2002/30594 (20130101)
A61F 2002/30604 (20130101)
A61F 2002/30784 (20130101)
A61F 2002/30879 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298266 Roy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Second Sight Medical Products, Inc. (Sylmar, California);  Advanced Medical Electronics Corporation (Maple Grove, Minnesota);  The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) Second Sight Medical Products, Inc. (Sylmar, California)
INVENTOR(S) Arup Roy (Valencia, California);  Avraham I. Caspi (Rehovot, Israel);  Gislin Dagnelie (Baltimore, Maryland);  Greg Seifert (St Paul, Minnesota);  Paul Gibson (Loretto, Minnesota)
ABSTRACT The present invention is a depth sensing visual prosthesis. By depth sensing objects within an image, items located at a certain depths from the user can be removed to declutter an image. The resulting image presents only objects within a range of depth from the visual prosthesis user. Depth sensing can be accomplished in various ways including structured light, time of flight, or preferably, a stereo camera pair.
FILED Thursday, December 07, 2017
APPL NO 15/835315
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/1624 (20130101)
A61F 9/08 (20130101) Original (OR) Class
A61F 9/0017 (20130101)
A61F 9/022 (20130101)
A61F 2250/0002 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/36046 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00671 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298327 Sun et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) Albert Einstein College of Medicine (Bronx, New York)
ASSIGNEE(S) Albert Einstein College of Medicine (Bronx, New York)
INVENTOR(S) Hui B. Sun (Chappaqua, New York);  Daniel J. Leong (Forest Hills, New York);  Neil J. Cobelli (Scarsdale, New York);  David M. Hirsh (Scarsdale, New York);  John A. Hardin (New York, New York);  Karen E. Sperling (New Rochelle, New York);  Sun J. Kim (New York, New York);  David C. Spray (Pelham, New York);  Chandan Guha (Scarsdale, New York);  Marwa Choudhury (Bronx, New York)
ABSTRACT Methods and formulations are provided for treating or preventing arthritis, in particular osteoarthritis, where the formulation to be administered to a subject for treating or preventing arthritis comprises carvacrol, curcumin, epigallocatechin-3-gallate and oligomeric procyanidins.
FILED Friday, September 11, 2020
APPL NO 17/017999
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0014 (20130101)
A61K 9/0019 (20130101)
A61K 9/0053 (20130101)
A61K 31/05 (20130101) Original (OR) Class
A61K 31/05 (20130101)
A61K 31/12 (20130101)
A61K 31/12 (20130101)
A61K 31/353 (20130101)
A61K 31/353 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 19/02 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298335 Rosen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Barry Philip Rosen (Coral Gables, Florida);  Masafumi Yoshinaga (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Barry Philip Rosen (Coral Gables, Florida);  Masafumi Yoshinaga (Miami, Florida)
ABSTRACT Certain embodiments of the invention pertain to a method of treating an infection in a subject caused by an infectious agent other than Escherichia coli, the method comprising administering to the subject arsinothricin or a salt thereof. The infectious agent other than E. coli can be a bacterium, protozoan, helminth, archaebacterium, or a fungus. In preferred embodiments, the infectious agent is Mycobacterium tuberculosis, Mycobacterium bovis, or Enterobacter cloacae. The invention also pertains to a method of treating an infection in a subject caused by an infectious agent, comprising administering to the subject arsinothricin or a salt thereof in combination with an inhibitor of phosphinothricin N-acetyltransferase or arsinothricin N-acetyltransferase. In certain such embodiments, the infectious agent expresses phosphinothricin N-acetyltransferase or arsinothricin N-acetyltransferase. Further embodiments provide compositions comprising arsinothricin or a salt thereof and an inhibitor of phosphinothricin N-acetyltransferase or arsinothricin N-acetyltransferase.
FILED Wednesday, October 17, 2018
APPL NO 16/163055
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/285 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1029 (20130101)

Enzymes
C12Y 203/01183 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298343 Weiss et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) ST. JUDE CHILDREN'S RESEARCH HOSPITAL (Memphis, Tennessee)
ASSIGNEE(S) ST. JUDE CHILDREN'S RESEARCH HOSPITAL (Memphis, Tennessee)
INVENTOR(S) Mitchell J. Weiss (Memphis, Tennessee);  Mondira Kundu (Memphis, Tennessee);  Christophe Lechauve (Bartlett, Tennessee)
ABSTRACT Methods for removing excess free α-globin in erythroid cells and treating a thalassemia using an agent that activates Unc-51 Like autophagy activating Kinase (ULK) are described.
FILED Friday, October 26, 2018
APPL NO 16/758986
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/436 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 7/06 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298408 Hanes et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (Manhasset, New York)
ASSIGNEE(S) THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (Manhasset, New York)
INVENTOR(S) William Hanes (East Setauket, New York);  Kevin J. Tracey (Old Greenwich, Connecticut);  Peder Olofsson (Lidingö, Sweden)
ABSTRACT Provided are CD4+ T-cell-based compositions and methods for treating hypertension.
FILED Friday, September 08, 2017
APPL NO 16/331306
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 38/45 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1029 (20130101)

Enzymes
C12Y 203/01006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298409 Friedlander et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania);  WASHINGTON UNIVERSITY (St. Louis, Missouri)
ASSIGNEE(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania);  WASHINGTON UNIVERSITY (St. Louis, Missouri)
INVENTOR(S) Robert Friedlander (Pittsburgh, Pennsylvania);  Hiroko Yano (Richmond Heights, Missouri)
ABSTRACT The present invention relates to methods of inhibiting neurodegeneration in a subject suffering from or genetically at risk and/or destined to develop Huntington's Disease comprising increasing, in neurons of the subject, the activity of the TIM23 mitochondrial protein import complex.
FILED Wednesday, November 20, 2019
APPL NO 16/689523
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/45 (20130101) Original (OR) Class
A61K 38/45 (20130101)
A61K 38/1709 (20130101)
A61K 38/1709 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1205 (20130101)
C12N 15/62 (20130101)

Enzymes
C12Y 207/11001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298410 Khalili et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Temple University of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
ASSIGNEE(S) Temple University of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
INVENTOR(S) Kamel Khalili (Bala Cynwyd, Pennsylvania);  Wenhui Hu (Cherry Hill, New Jersey);  Yonggang Zhang (Maple Shade, New Jersey)
ABSTRACT Compositions for specifically cleaving target sequences in retroviruses include nucleic acids encoding a Clustered Regularly Interspace Short Palindromic Repeat (CRISPR) associated endonuclease and a guide RNA sequence complementary to one or more target nucleic acid sequences in a retrovirus genome.
FILED Wednesday, June 01, 2016
APPL NO 15/578372
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/465 (20130101) Original (OR) Class
A61K 48/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/18 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/11 (20130101)
C12N 15/907 (20130101)
C12N 15/1132 (20130101)
C12N 2310/10 (20130101)
C12N 2310/20 (20170501)
C12N 2320/11 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298411 Khalili et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Temple University of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
ASSIGNEE(S) Temple University of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
INVENTOR(S) Kamel Khalili (Bala Cynwyd, Pennsylvania);  Wenhui Hu (Cherry Hill, New Jersey)
ABSTRACT A method of treating a subject having a retroviral infection, by administering to the subject a therapeutically effective amount of a composition comprising a vector encoding a CRISPR-associated endonuclease and at least two guide RNAs, wherein the guide RNAs are complementary to two target sequences spanning from the 5′- to 3′-LTRs of the sequence in the retrovirus, and eradicating the retroviral infection. A method of immunizing a subject at risk of retroviral infection, by administering a prophylactically effective amount of a composition comprising a Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated endonuclease, and two or more different guide RNAs (gRNAs), wherein each of the at least two gRNAs is complementary to a different target nucleic acid sequence in a long terminal repeat (LTR) of proviral DNA of a retrovirus to the subject, and preventing retroviral infection in the subject.
FILED Wednesday, January 31, 2018
APPL NO 15/884427
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0034 (20130101)
A61K 35/12 (20130101)
A61K 38/465 (20130101) Original (OR) Class
A61K 45/06 (20130101)
A61K 48/00 (20130101)
A61K 48/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 9/22 (20130101)
C12N 15/111 (20130101)
C12N 2310/20 (20170501)
C12N 2320/30 (20130101)
C12N 2740/16063 (20130101)

Enzymes
C12Y 301/21 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298423 Jeffries et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Nursing Research (NINR)
National Science Foundation (NSF)
Directorate of Technology
Translational Impacts (TI)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Eric M. Jeffries (West New York, New Jersey);  Noah R. Johnson (Pittsburgh, Pennsylvania);  Daniel Long (Pittsburgh, Pennsylvania);  Yadong Wang (Bradford Woods, Pennsylvania)
ABSTRACT Compositions are provided herein comprising a coacervate of a polycationic polymer, a polyanionic polymer, and platelet-rich plasma and/or serum, or a fraction or concentrate thereof. The composition is useful in wound healing. Compositions also are provided that comprise a hydrogel comprising TIMP-3; and a complex of a polycationic polymer, a polyanionic polymer, FGF-2 and SDF-1α embedded in the hydrogel, which is useful in treating a myocardial infarction.
FILED Friday, March 03, 2017
APPL NO 16/080812
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/0019 (20130101)
A61K 35/16 (20130101)
A61K 35/19 (20130101)
A61K 38/18 (20130101)
A61K 38/177 (20130101)
A61K 38/195 (20130101)
A61K 38/1825 (20130101)
A61K 47/34 (20130101)
A61K 47/36 (20130101) Original (OR) Class
A61K 47/42 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 15/40 (20130101)
A61L 15/44 (20130101)
A61L 15/225 (20130101)
A61L 15/225 (20130101)
A61L 27/18 (20130101)
A61L 27/20 (20130101)
A61L 27/26 (20130101)
A61L 27/26 (20130101)
A61L 27/52 (20130101)
A61L 27/54 (20130101)
A61L 27/56 (20130101)
A61L 27/225 (20130101)
A61L 27/3616 (20130101)
A61L 31/16 (20130101)
A61L 31/041 (20130101)
A61L 31/042 (20130101)
A61L 31/046 (20130101)
A61L 31/145 (20130101)
A61L 2300/25 (20130101)
A61L 2300/252 (20130101)
A61L 2300/414 (20130101)
A61L 2300/418 (20130101)
A61L 2400/04 (20130101)
A61L 2430/20 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/10 (20180101)

Compositions of Macromolecular Compounds
C08L 5/10 (20130101)
C08L 5/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298424 Deming et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Timothy J. Deming (Los Angeles, California);  Michael V. Sofroniew (Los Angeles, California);  Shanshan Zhang (Los Angeles, California)
ABSTRACT The present invention is directed to copolypeptide hydrogels (DCH) containing non-ionic hydrophilic residues (DCHEO), incorporation of thermoresponsive elements into DCHEO, to generate thermoresponsive DCH (DCHT), and hydrogels that include a combination of DCHEO and DCHT. The invention includes preparation, uses, compositions containing the hydrogels and methods of tuning the hydrogels. The hydrogels can be used to deliver an agent or cells to an organism.
FILED Thursday, October 01, 2015
APPL NO 15/516211
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 35/12 (20130101)
A61K 35/30 (20130101)
A61K 47/42 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 11/02 (20130101)
C12N 11/04 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/46 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/0076 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298441 Payne et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado)
INVENTOR(S) Karin A. Payne (Denver, Colorado);  Stephanie Bryant (Boulder, Colorado);  Virginia Ferguson (Golden, Colorado);  Nancy Hadley-Miller (Denver, Colorado);  Robert McLeod (Boulder, Colorado)
ABSTRACT The present invention relates to the unexpected discovery of 3D printed biomimetics of growth plate cartilage and methods using the same for the treatment of growth plate defects. In certain embodiments, the methods prevent the growth of bony bars at the site of growth plate injury, thereby preventing growth arrest and/or deformity.
FILED Tuesday, November 06, 2018
APPL NO 16/762835
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/4886 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/48 (20130101)
A61L 27/52 (20130101) Original (OR) Class
A61L 27/58 (20130101)
A61L 2300/25 (20130101)
A61L 2300/236 (20130101)
A61L 2300/414 (20130101)
A61L 2300/416 (20130101)
A61L 2430/06 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 80/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298443 Kaplan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Trustees of Tufts College (Medford, Massachusetts)
ASSIGNEE(S) Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S) David L. Kaplan (Concord, Massachusetts);  Sarah Lightfoot Vidal (Woburn, Massachusetts);  Rosalyn Abbott (Lynnfield, Massachusetts);  Siwei Zhao (Waltham, Massachusetts);  Dana Cairns (Sommerville, Massachusetts);  Fiorenzo G. Omenetto (Lexington, Massachusetts)
ABSTRACT The present invention provides, in some embodiments, multi-layer silk compositions including a first layer comprising silk fibroin and keratinocytes, a second layer comprising silk fibroin and fibroblasts, a third layer comprising silk fibroin and adipocytes, and a plurality of nervous system cells, wherein at least some of the plurality of nervous system cells span at least two layers, and methods of making and using the same. In some embodiments, provided methods and compositions further include immune cells and/or endothelial cells.
FILED Friday, June 30, 2017
APPL NO 16/314169
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/60 (20130101) Original (OR) Class
A61L 27/227 (20130101)
A61L 27/3637 (20130101)
A61L 27/3641 (20130101)
A61L 27/3813 (20130101)
A61L 27/3834 (20130101)
A61L 27/3891 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0698 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298452 Federspiel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) William J. Federspiel (Pittsburgh, Pennsylvania);  Brian Joseph Frankowski (Imperial, Pennsylvania);  James F. Antaki (Allison Park, Pennsylvania);  Christian Andres Bermudez (Philadelphia, Pennsylvania);  Richard Garrett Jeffries (Philadelphia, Pennsylvania);  William R. Wagner (Gibsonia, Pennsylvania);  Sang-Ho Ye (Cheswick, Pennsylvania)
ABSTRACT A extracorporeal system for lung assist includes a housing, a blood flow inlet in fluid connection with the housing; a blood flow outlet in fluid connection with the housing; a plurality of hollow gas permeable fibers adapted to permit diffusion of gas between blood and an interior of the hollow gas permeable fibers, the plurality of hollow gas permeable fibers being positioned between the blood flow inlet and the blood flow outlet such that blood flows around the plurality of hollow gas permeable fibers when flowing from the blood flow inlet to the blood flow outlet; a gas inlet in fluid connection with the housing and in fluid connection with inlets of the plurality of hollow gas permeable fibers; a gas outlet in fluid connection with the housing and in fluid connection with outlets of the plurality of hollow gas permeable fibers; and at least one moving element to create velocity fields in blood flow contacting the plurality of hollow gas permeable fibers. The plurality of hollow gas permeable fibers may extend generally perpendicular to the direction of bulk flow of blood through the housing.
FILED Saturday, September 22, 2018
APPL NO 16/139015
ART UNIT 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 1/262 (20140204)
A61M 1/267 (20140204)
A61M 1/1698 (20130101)
A61M 1/3667 (20140204) Original (OR) Class
A61M 60/40 (20210101)
A61M 60/82 (20210101)
A61M 60/113 (20210101)
A61M 60/205 (20210101)
A61M 60/419 (20210101)
A61M 60/818 (20210101)
A61M 2205/7536 (20130101)
A61M 2206/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298563 Dong et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Pulsethera, Inc. (Chestnut Hill, Massachusetts)
ASSIGNEE(S) Pulsethera, Inc. (Chestnut Hill, Massachusetts)
INVENTOR(S) Pu-Ting Dong (Boston, Massachusetts);  Jie Hui (Boston, Massachusetts);  Ji-Xin Cheng (Newton, Massachusetts);  Yifan Zhu (Allston, Massachusetts)
ABSTRACT Methods of the present invention comprise photoinactivation of catalase in combination with low-concentration peroxide solutions and/or ROS generating agents to provide antibacterial effects.
FILED Wednesday, July 28, 2021
APPL NO 17/387579
ART UNIT 1799 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 33/40 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 2/10 (20130101)
A61L 2/208 (20130101)
A61L 2101/02 (20200801)
A61L 2202/26 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/062 (20130101) Original (OR) Class
A61N 5/0616 (20130101)
A61N 5/0624 (20130101)
A61N 2005/0635 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298570 Christiano et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Angela M. Christiano (Mahwah, New Jersey);  Raphael Clynes (West Nyack, New York)
ABSTRACT The invention provides for methods for treating a hair loss disorder in a subject by administering a Janus Kinase/Signal Transducers and Activators of Transcription inhibitor.
FILED Tuesday, March 12, 2019
APPL NO 16/299382
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 8/41 (20130101)
A61K 8/64 (20130101)
A61K 8/4953 (20130101)
A61K 31/52 (20130101)
A61K 31/63 (20130101)
A61K 31/137 (20130101)
A61K 31/277 (20130101)
A61K 31/407 (20130101)
A61K 31/437 (20130101)
A61K 31/506 (20130101)
A61K 31/519 (20130101)
A61K 31/529 (20130101)
A61K 31/553 (20130101)
A61K 31/713 (20130101)
A61K 31/5377 (20130101)
A61K 31/7052 (20130101)
A61K 2800/782 (20130101)

Specific Use of Cosmetics or Similar Toilet Preparations
A61Q 7/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298913 Bottlang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Apex Biomedical Company, LLC (Clackamas, Oregon)
ASSIGNEE(S) WaveCel, LLC (Wilsonville, Oregon)
INVENTOR(S) Michael Bottlang (Happy Valley, Oregon);  Jeffrey Bennett (Portland, Oregon)
ABSTRACT An impact-absorbing structure that includes a plurality of interconnected cells forming a sheet, each cell having a sidewall and a longitudinal axis. Each cell may be configured to absorb energy through plastic deformation in response to an applied load, and a sidewall of at least one cell may include a geometric perturbation that is oriented in a direction that is not parallel to the longitudinal axis of the cell. The geometric perturbation may reduce the load required to cause plastic deformation of the cell.
FILED Friday, May 13, 2016
APPL NO 15/154707
ART UNIT 1784 — Miscellaneous Articles, Stock Material
CURRENT CPC
Hats; Head Coverings
A42B 3/065 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 3/12 (20130101) Original (OR) Class

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 80/00 (20141201)

Springs; Shock-absorbers; Means for Damping Vibration
F16F 7/121 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299461 Jiao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) HAWAII BIOTECH, INC. (Honolulu, Hawaii)
ASSIGNEE(S) HAWAII BIOTECH, INC. (Honolulu, Hawaii)
INVENTOR(S) Guan-Sheng Jiao (Aiea, Hawaii);  Seong Jin Kim (Honolulu, Hawaii);  Alan T. Johnson (Kaneohe, Hawaii)
ABSTRACT Compounds of formula I are provided:
wherein X is NH, or CH2, Y is a single bond, or —CHR5—, R1 is H, C1-C4 alkyl, or C1-C4 hydroxyalkyl, R2 and R2′ are each independently H, C1-C4 alkyl, or C1-C4 hydroxyalkyl, each R3 is independently H, halo, —CF3, C1-C4 alkyl, or C1-C4 alkoxy, C3 perhaloalkyl, each R4 is independently H, halo, or C1-C4 alkyl, R5 is C1-C4 alkoxy, r is integer from 0 to 3; and p is integer from 0 to 3.
FILED Tuesday, March 12, 2019
APPL NO 16/979503
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 213/54 (20130101)
C07D 213/61 (20130101)
C07D 213/65 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299476 Newman et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland)
ASSIGNEE(S) THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Rockville, Maryland)
INVENTOR(S) Amy Hauck Newman (Phoenix, Maryland);  Vivek Kumar (Baltimore, Maryland);  Anver Basha Shaik (Baltimore, Maryland)
ABSTRACT Disclosed herein novel dopamine D3 receptor selective antagonists/partial agonists compounds with high affinity and metabolic stability useful for the treatment of psychiatric and neurological disorders and as research and diagnostic tools. Also disclosed are methods of making the compounds.
FILED Wednesday, March 08, 2017
APPL NO 16/084093
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/36 (20180101)

Heterocyclic Compounds
C07D 403/12 (20130101) Original (OR) Class
C07D 405/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299480 Turkson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) University of Hawaii (Honolulu, Hawaii)
ASSIGNEE(S) University of Hawaii (Honolulu, Hawaii)
INVENTOR(S) James Turkson (Honolulu, Hawaii);  Peibin Yue (Honolulu, Hawaii);  Marcus Tius (Honolulu, Hawaii);  Christine Brotherton-Pleiss (Honolulu, Hawaii);  Francisco Javier Lopez Tapia (Honolulu, Hawaii)
ABSTRACT The present disclosure provides pharmaceutical compositions comprising 2-arylsulfonamido-N-arylacetamide derivatized Stat3 inhibitors and certain pharmaceutically acceptable salts thereof, and methods of their use.
FILED Tuesday, January 23, 2018
APPL NO 16/480090
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0053 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 401/12 (20130101)
C07D 401/14 (20130101)
C07D 403/12 (20130101)
C07D 403/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299496 Thakur et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Northeastern University (Boston, Massachusetts);  University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts);  University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Ganeshsingh A. Thakur (Cambridge, Massachusetts);  Abhijit R. Kulkarni (Boston, Massachusetts);  Roger Lee Papke (Gainesville, Florida)
ABSTRACT Compounds are provided which bind to an allosteric site on the mammalian alpha-7 nicotinic acetylcholine receptor (alpha-7 nAChR) and act as positive allosteric modulators with or without allosteric agonist activity. The compounds are useful in diagnosing, preventing, or treating a variety of disorders involving cognition, learning, memory, neurodegeneration, drug addiction, inflammation, chronic pain, and neuropathic pain. The compounds also can be used to enhance memory and learning in normal individuals.
FILED Thursday, July 23, 2015
APPL NO 15/328112
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 221/16 (20130101)
C07D 401/04 (20130101)
C07D 401/10 (20130101)
C07D 401/12 (20130101)
C07D 405/04 (20130101)
C07D 409/04 (20130101)
C07D 409/10 (20130101)
C07D 409/14 (20130101)
C07D 417/04 (20130101)
C07D 491/048 (20130101)
C07D 495/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299509 Cheng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Jianjun Cheng (Champaign, Illinois);  Kaimin Cai (Urbana, Illinois);  Jin Yu (Urbana, Illinois)
ABSTRACT Disclosed are compounds for the selective labeling of cell-surface sugars in cancer cells. The compounds are activatable by triggers specific to cancer cells, and, when metabolized, label a cancer cell surface sugar with an azide chemical group. Facilitated by a click chemistry reaction, combination of the cell surface-expressed azide with a alkynyl-drug conjugate enables efficient targeted drug delivery to cancer cells with reduced toxicity. Also disclosed are compounds for delivering a drug to an azide-bearing cancer cell, and methods of treating cancer using the compounds.
FILED Monday, February 12, 2018
APPL NO 16/485090
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/704 (20130101)
A61K 31/5365 (20130101)
A61K 47/549 (20170801)
A61K 47/555 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 15/18 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299515 Nguyen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Quyen T. Nguyen (La Jolla, California);  Mike Whitney (San Diego, California);  Dina Hingorani (San Diego, California);  Roger Y. Tsien (Eugene, Oregon);  Stephen Adams (Poway, California)
ABSTRACT The present invention provides methods for guiding preservation of human neurons or human nerves during surgery by administering a fluorescently-labeled peptide that specifically binds to the human neurons or human nerves. The invention further provides human neuron or nerve targeting molecules comprising fluorescently-labeled peptides that specifically bind to human neurons or human nerves and compositions thereof.
FILED Thursday, August 02, 2018
APPL NO 16/635133
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0014 (20130101)
A61K 9/0019 (20130101)
A61K 41/0057 (20130101)
A61K 45/06 (20130101)
A61K 47/64 (20170801)
A61K 49/0056 (20130101)

Peptides
C07K 7/00 (20130101)
C07K 7/08 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299520 Vedantam et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
ASSIGNEE(S) Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S) Gayatri Vedantam (Tucson, Arizona);  Virinchipuram Viswanathan (Tucson, Arizona)
ABSTRACT The invention features engineered probiotic lacto acid bacteria (LAB) expressing a chimeric Clostridium difficile/Lactobacillus acidophilus SlpA, or fragment thereof, and its use for the treatment or prevention of Clostridium difficile infection and gut colonization.
FILED Tuesday, September 25, 2018
APPL NO 16/651160
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0053 (20130101)
A61K 38/00 (20130101)

Peptides
C07K 14/33 (20130101) Original (OR) Class
C07K 14/335 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/90 (20130101)
C12N 15/62 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299524 Yamada et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
INVENTOR(S) Kaori Yamada (Lombard, Illinois);  Asrar Malik (Hinsdale, Illinois)
ABSTRACT A construct composed of a Kinesin-derived Angiogenesis Inhibitor peptide and one or more carrier moieties and/or stabilizing moieties is provided as are methods for inhibiting angiogenesis and treating a disease or condition characterized by excessive vascularity.
FILED Thursday, August 31, 2017
APPL NO 16/325006
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/17 (20130101)
A61K 47/543 (20170801)
A61K 47/549 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/00 (20180101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 23/00 (20130101)

Peptides
C07K 14/435 (20130101) Original (OR) Class
C07K 2319/10 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299526 Lim et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S) UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah)
INVENTOR(S) Carol S. Lim (Salt Lake City, Utah);  Phong Lu (Salt Lake City, Utah)
ABSTRACT Disclosed are peptides comprising a p53 peptide and a BH3-only protein. In some aspects, wherein the BH3-only protein is BAD, BID, BIM, NOXA. Disclosed are nucleic acid sequences comprising a sequence capable of encoding a p53 peptide operably linked to a nucleic acid sequence capable of encoding a BH3-only protein. Disclosed are nucleic acid sequences comprising a sequence capable of encoding one or more of the peptides disclosed herein. Disclosed are vectors comprising a nucleic acid sequence, wherein the nucleic acid sequence is capable of encoding one or more of the peptides disclosed herein. Also disclosed are methods of using the disclosed peptides, nucleic acid sequences, and vectors.
FILED Thursday, May 16, 2019
APPL NO 16/414683
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/4746 (20130101)
C07K 14/4747 (20130101) Original (OR) Class
C07K 2319/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299535 Smith
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) VANDERBILT UNIVERSITY (Nashville, Tennessee)
ASSIGNEE(S) VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S) Scott A. Smith (Nashville, Tennessee)
ABSTRACT The present disclosure is directed to antibodies binding to Aspergillus allergens and methods for use thereof.
FILED Tuesday, October 15, 2019
APPL NO 16/653147
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0002 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/10 (20180101)

Peptides
C07K 14/47 (20130101)
C07K 16/14 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/31 (20130101)
C07K 2317/54 (20130101)
C07K 2317/55 (20130101)
C07K 2317/94 (20130101)
C07K 2317/565 (20130101)
C07K 2317/622 (20130101)
C07K 2319/30 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56961 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299536 Frigault et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Matthew J. Frigault (Philadelphia, Pennsylvania);  Yangbing Zhao (Cherry Hill, New Jersey);  John Scholler (Narberth, Pennsylvania);  Carl H. June (Merion Station, Pennsylvania)
ABSTRACT The present invention provides compositions and methods for generating a genetically modified T cells comprising a chimeric antigen receptor (CAR) having an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain, wherein the T cell exhibits prolonged exponential expansion in culture that is ligand independent and independent of the addition of exogenous cytokines or feeder cells.
FILED Thursday, June 21, 2018
APPL NO 16/014133
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/7051 (20130101)
C07K 14/70521 (20130101)
C07K 16/18 (20130101) Original (OR) Class
C07K 16/30 (20130101)
C07K 2319/33 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101)
C12N 15/86 (20130101)
C12N 2510/00 (20130101)
C12N 2740/15041 (20130101)
C12N 2840/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299546 Chien et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Christopher D. Chien (Falls Church, Virginia);  Terry J. Fry (Bethesda, Maryland)
ABSTRACT An embodiment of the invention provides a chimeric antigen receptor (C AR) comprising an antigen binding domain specific for FLT3, a transmembrane domain, and an intracellular T cell signaling domain. Nucleic acids, recombinant expression vectors, host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions relating to the CARs are disclosed. Methods of detecting the presence of a proliferative disorder, e.g., cancer, in a mammal and methods of treating or preventing a proliferative disorder, e.g., cancer, in a mammal are also disclosed.
FILED Friday, May 26, 2017
APPL NO 16/304552
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 39/395 (20130101)
A61K 2039/505 (20130101)
A61K 2039/5156 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/2809 (20130101)
C07K 16/2815 (20130101)
C07K 16/2863 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/53 (20130101)
C07K 2317/64 (20130101)
C07K 2317/622 (20130101)
C07K 2319/03 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57426 (20130101)
G01N 33/57492 (20130101)
G01N 2333/715 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299698 Sharei et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Armon R. Sharei (Watertown, Massachusetts);  Klavs F. Jensen (Lexington, Massachusetts);  James Robbins Abshire (Cambridge, Massachusetts);  Jacquin Clarence Niles (Arlington, Massachusetts)
ABSTRACT The current subject matter includes methods, systems, articles, and techniques to deliver material to anucleate cells, such as red blood cells. Using a rapid deformation based microfluidic system, loading of red blood cells with macromolecules of different sizes has been shown. Although delivery to some mammalian cells, such as cancer cell lines and fibroblasts had been previously demonstrated using this technique, those designs were incompatible with RBCs that have dramatically different physical properties. Through the use of smaller constriction sizes, high speeds and different buffers successful delivery to red blood cells can be achieved. By enabling robust delivery to red blood cells in a simple, scalable manner, the current subject matter can be implemented in a diversity of applications that deliver material to study red blood cell diseases and/or use red blood cells as a therapeutic platform. Related apparatus, systems, techniques, and articles are also described.
FILED Tuesday, January 09, 2018
APPL NO 15/865901
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/18 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 23/16 (20130101) Original (OR) Class
C12M 35/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0641 (20130101)
C12N 5/0644 (20130101)
C12N 15/87 (20130101)
C12N 2521/00 (20130101)
C12N 2527/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299711 Hebrok et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Matthias Hebrok (Belmont, California);  Holger Andreas Russ (San Francisco, California);  Gopika G. Nair (San Francisco, California)
ABSTRACT Methods are provided for the simple, fast, effective and safe directed differentiation of embryonic stem cells into the mature beta cells of enriched beta clusters, wherein the beta cells rapidly and reliably secrete insulin in response to glucose levels. The cells are useful transplant therapeutics for diabetic individuals. These cells can also be used for drug screening purposes to identify factors/chemicals capable of increasing beta cell functions, proliferation, survival, and resistance to immune assault.
FILED Friday, April 07, 2017
APPL NO 16/092166
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/39 (20130101)
A61K 35/545 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 3/10 (20180101)
A61P 5/48 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0676 (20130101)
C12N 5/0678 (20130101) Original (OR) Class
C12N 2500/25 (20130101)
C12N 2501/11 (20130101)
C12N 2501/15 (20130101)
C12N 2501/16 (20130101)
C12N 2501/117 (20130101)
C12N 2501/195 (20130101)
C12N 2501/395 (20130101)
C12N 2501/415 (20130101)
C12N 2501/727 (20130101)
C12N 2501/999 (20130101)
C12N 2506/02 (20130101)
C12N 2535/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299714 Vunjak-Novakovic et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in The City of New York (New York, New York)
INVENTOR(S) Gordana Vunjak-Novakovic (New York, New York);  Keith Yeager (Jersey City, New Jersey);  Kacey Ronaldson (Midlothian, Virginia);  Stephen Ma (New York, New York);  Timothy Chen (New York, New York)
ABSTRACT A cardiac organoid containing 3-D matter of adult human heart tissue.
FILED Wednesday, May 11, 2016
APPL NO 15/151751
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/34 (20130101)
A61K 35/545 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/3826 (20130101)
A61L 27/3895 (20130101)
A61L 2430/20 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0657 (20130101)
C12N 5/0697 (20130101) Original (OR) Class
C12N 2503/04 (20130101)
C12N 2506/45 (20130101)
C12N 2513/00 (20130101)
C12N 2529/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299720 Hanzel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Pacific Biosciences of California, Inc. (Menlo Park, California)
ASSIGNEE(S) Pacific Biosciences of California, Inc. (Menlo Park, California)
INVENTOR(S) David K. Hanzel (Palo Alto, California);  Geoff Otto (Brookline, Massachusetts);  Paul S. Peluso (Newark, California);  Thang Pham (Mountain View, California);  David R. Rank (Pacific Grove, California);  Fred Christians (Los Altos Hills, California);  Arekadiusz Bibillo (Cupertino, California);  Insil Park (Fremont, California);  Sonya Clark (Oakland, California);  John Lyle (Fremont, California)
ABSTRACT Compositions that include polymerases with features for improving entry of nucleotide analogues into active site regions and for coordinating with the nucleotide analogues in the active site region are provided. Methods of making the polymerases and of using the polymerases in sequencing and DNA replication and amplification as well as kinetic models of polymerase activity and computer-implemented methods of using the models are also provided.
FILED Tuesday, July 14, 2020
APPL NO 16/928940
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 2319/20 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1252 (20130101) Original (OR) Class

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6827 (20130101)
C12Q 1/6869 (20130101)

Enzymes
C12Y 207/07007 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/52 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299730 Shendure et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) University of Washington Through Its Center for Commercialization (Seattle, Washington)
ASSIGNEE(S) UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington)
INVENTOR(S) Jay Ashok Shendure (Seattle, Washington);  Jerrod Joseph Schwartz (Seattle, Washington);  Andrew Colin Adey (Seattle, Washington);  Cho li Lee (Seattle, Washington);  Joseph Brian Hiatt (Seattle, Washington);  Jacob Otto Kitzman (Seattle, Washington);  Akash Kumar (Seattle, Washington)
ABSTRACT Contiguity information is important to achieving high-quality de novo assembly of mammalian genomes and the haplotype-resolved resequencing of human genomes. The methods described herein pursue cost-effective, massively parallel capture of contiguity information at different scales.
FILED Monday, October 28, 2019
APPL NO 16/665800
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1093 (20130101) Original (OR) Class

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/582 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299733 Rando et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
ASSIGNEE(S) UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
INVENTOR(S) Oliver Rando (Natick, Massachusetts);  Upasna Sharma (Shrewsbury, Massachusetts);  Colin Conine (Brighton, Massachusetts)
ABSTRACT Methods and compositions directed to altering a population of sRNAs in a sperm using vesicles isolated from an epididymosome are provided. Methods and compositions directed to altering a population of sRNAs in an oocyte using vesicles isolated from an epididymosome are also provided. Methods for altering an sRNA population in a sperm or an oocyte can be used to prevent, or reduce the severity of, a disease, disorder, or condition that would otherwise be inherited by progeny. For example, certain epigenetic inherited conditions due to paternal effects, such as certain metabolic and stress disorders and conditions, can be ameliorated in progeny using sperm or oocytes having an altered sRNA population.
FILED Wednesday, July 12, 2017
APPL NO 16/315004
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/43 (20130101)
A61B 17/435 (20130101)

Veterinary Instruments, Implements, Tools, or Methods
A61D 19/02 (20130101)
A61D 19/04 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/0034 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/061 (20130101)
C12N 5/0604 (20130101)
C12N 15/111 (20130101)
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2310/141 (20130101)
C12N 2320/30 (20130101)
C12N 2501/65 (20130101)
C12N 2510/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299734 Aronin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
INVENTOR(S) Neil Aronin (Newtonville, Massachusetts);  Phillip D. Zamore (Northboro, Massachusetts)
ABSTRACT The present invention relates to the discovery of an effective treatment for a variety of gain-of-function diseases, in particular, Huntington's disease (HD). The present invention utilizes RNA Interference technology (RNAi) against polymorphic regions in the genes encoding various gain-of-function mutant proteins resulting in an effective treatment for the gain-of-function disease.
FILED Friday, May 17, 2019
APPL NO 16/415826
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/005 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/02 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/06 (20130101)
C12N 15/111 (20130101)
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2310/531 (20130101)
C12N 2310/3515 (20130101)
C12N 2320/30 (20130101)
C12N 2320/34 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299755 Liu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) David R. Liu (Cambridge, Massachusetts);  Johnny Hao Hu (Cambridge, Massachusetts)
ABSTRACT Some aspects of this disclosure provide compositions, methods, systems, and kits for controlling the activity and/or improving the specificity of RNA-programmable endonucleases, such as Cas9. For example, provided are guide RNAs (gRNAs) that are engineered to exist in an “on” or “off” state, which control the binding and hence cleavage activity of RNA-programmable endonucleases. Some aspects of this disclosure provide mRNA-sensing gRNAs that modulate the activity of RNA-programmable endonucleases based on the presence or absence of a target mRNA. Some aspects of this disclosure provide gRNAs that modulate the activity of an RNA-programmable endonuclease based on the presence or absence of an extended DNA (xDNA).
FILED Thursday, February 20, 2020
APPL NO 16/796323
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 9/96 (20130101)
C12N 15/01 (20130101)
C12N 15/63 (20130101)
C12N 15/102 (20130101)
C12N 15/113 (20130101)
C12N 15/115 (20130101)
C12N 15/907 (20130101) Original (OR) Class
C12N 2310/10 (20130101)
C12N 2310/12 (20130101)
C12N 2310/16 (20130101)
C12N 2310/53 (20130101)
C12N 2310/3519 (20130101)
C12N 2320/53 (20130101)

Enzymes
C12Y 301/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299767 Church et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) George M. Church (Brookline, Massachusetts);  Je-Hyuk Lee (Allston, Massachusetts);  Richard C. Terry (Carlisle, Massachusetts);  Evan R. Daugharthy (Cambridge, Massachusetts)
ABSTRACT Methods of making a three-dimensional matrix of nucleic acids within a cell is provided.
FILED Wednesday, June 30, 2021
APPL NO 17/363097
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101) Original (OR) Class
C12Q 1/6806 (20130101)
C12Q 1/6844 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6874 (20130101)
C12Q 2565/501 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299770 Samusik et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California)
INVENTOR(S) Nikolay Samusik (Mountain View, California);  Garry P. Nolan (Redwood City, California);  Yury Goltsev (Stanford, California)
ABSTRACT A method for analyzing planar sample is provided. In some cases the method comprises: (a) incubating the planar sample with a capture agent that is linked to an oligonucleotide, wherein the capture agent specifically binds to complementary sites in the planar sample; (b) reading a fluorescent signal caused by extension of a primer that is hybridized to the oligonucleotide, using fluorescence microscopy. Several implementations of the method, and multiplexed versions of the same, are also provided.
FILED Friday, January 04, 2019
APPL NO 16/240463
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6804 (20130101)
C12Q 1/6804 (20130101)
C12Q 1/6804 (20130101)
C12Q 1/6818 (20130101) Original (OR) Class
C12Q 2565/101 (20130101)
C12Q 2565/1015 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299771 Lee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Jeunghoon Lee (Boise, Idaho);  Bernard Yurke (Boise, Idaho);  Elton Graugnard (Boise, Idaho);  Will Hughes (Blacksburg, Idaho);  Bert Huttanus (Blacksburg, Virginia)
ASSIGNEE(S) Boise State University (Boise, Idaho)
INVENTOR(S) Jeunghoon Lee (Boise, Idaho);  Bernard Yurke (Boise, Idaho);  Elton Graugnard (Boise, Idaho);  Will Hughes (Blacksburg, Idaho);  Bert Huttanus (Blacksburg, Virginia)
ABSTRACT The present invention provides compositions and methods for colorimetric detection schemes for detecting a variety of biomolecules. The compositions and methods employ DNA hybridization chain reaction for catalytic aggregation of gold nanoparticles. In this catalytic aggregation scheme, a single target DNA strand triggers the formation of multiple inter-particle linkages in contrast to the single linkage formed in conventional direct aggregation schemes.
FILED Monday, January 22, 2018
APPL NO 15/877128
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/682 (20130101) Original (OR) Class
C12Q 1/682 (20130101)
C12Q 2525/197 (20130101)
C12Q 2525/301 (20130101)
C12Q 2563/137 (20130101)
C12Q 2563/155 (20130101)
C12Q 2565/113 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299776 Ellington et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Aeronautics and Space Administration (NASA)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Andrew Ellington (Austin, Texas);  Cheulhee Jung (Austin, Texas);  Sheng Cai (Zhejiang, China PRC);  Sanchita Bhadra (Austin, Texas);  John N. Milligan (Austin, Texas);  Daniel Garry (Austin, Texas);  Raghav Shroff (Austin, Texas)
ABSTRACT Disclosed are compositions and methods for nucleic acid amplification and detection. Specifically, disclosed herein are compositions and methods that allow for amplification of nucleic acids at a wide variety of temperatures. This includes a polymerase which is thermostable at high temperatures, and a method of amplification that can be conducted at relatively low temperatures.
FILED Thursday, May 10, 2018
APPL NO 16/612020
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1252 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/6853 (20130101) Original (OR) Class
C12Q 2521/101 (20130101)
C12Q 2525/301 (20130101)
C12Q 2527/101 (20130101)
C12Q 2531/101 (20130101)
C12Q 2537/1373 (20130101)
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299782 Szallasi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Children's Medical Center Corporation (Boston, Massachusetts);  The Technical University of Denmark (Lyngby, Denmark);  Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts);  The Technical University of Denmark (Lyngby, Denmark);  Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Zoltan Szallasi (Boston, Massachusetts);  Nicolai Juul Birkbak (Københaven Ø, Denmark);  Aron Eklund (Københaven Ø, Denmark);  Daniel Silver (Wayland, Massachusetts);  Zhigang Wang (Chestnut Hill, Massachusetts);  Andrea Richardson (Chestnut Hill, Massachusetts)
ABSTRACT The present invention is based, in part, on the identification of novel methods for defining predictive biomarkers of response to anti-cancer drugs.
FILED Friday, December 28, 2018
APPL NO 16/235247
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6874 (20130101) Original (OR) Class
C12Q 1/6886 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/154 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299785 Wong et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Children's Hospital Medical Center (Cincinnati, Ohio);  University of Cincinnati (Cincinnati, Ohio)
ASSIGNEE(S) CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio);  UNIVERSITY OF CINCINNATI (Cincinnati, Ohio)
INVENTOR(S) Hector R. Wong (Cincinnati, Ohio);  Christopher John Lindsell (Cincinnati, Ohio)
ABSTRACT Methods and compositions disclosed herein generally relate to methods of identifying, validating, and measuring clinically relevant, quantifiable biomarkers of diagnostic and therapeutic responses for blood, vascular, cardiac, and respiratory tract dysfunction, particularly as those responses relate to septic shock in pediatric patients. In particular, the invention relates to identifying two or more biomarkers associated with septic shock in pediatric patients, obtaining a sample from a pediatric patient having at least one indication of septic shock, then quantifying from the sample an amount of two or more of said biomarkers, wherein the level of said biomarker correlates with a predicted outcome.
FILED Tuesday, August 13, 2019
APPL NO 16/539128
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/106 (20130101)
C12Q 2600/112 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299790 Flavell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Richard Flavell (Guilford, Connecticut);  Noah Palm (New Haven, Connecticut);  Marcel de Zoete (New Haven, Connecticut)
ABSTRACT The invention relates to the identification of secretory antibody-bound bacteria in the microbiota in a subject that influence the development and progression of inflammatory diseases and disorders. Thus, the invention relates to compositions and methods for detecting and identifying the constituents of a subject's microbiota, methods of modifying the constituents of the microbiota, and methods for treating inflammatory diseases and disorders in a subject in need thereof.
FILED Friday, August 14, 2020
APPL NO 16/993529
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/741 (20130101)
A61K 39/0208 (20130101)
A61K 2035/115 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/689 (20130101) Original (OR) Class
C12Q 1/6806 (20130101)
C12Q 1/6806 (20130101)
C12Q 2537/159 (20130101)
C12Q 2563/131 (20130101)
C12Q 2565/113 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300116 Hashemi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Saeed Hashemi (Minneapolis, Minnesota);  William Keith Durfee (Edina, Minnesota)
ABSTRACT Hydraulic cylinders and methods of fabricating hydraulic cylinders, including long-stroke rolling diaphragm cylinders with any stroke length. In some embodiments, the cylinders are manufactured to have a stroke length to bore diameter (“stroke-to-bore”) ratio optionally greater than 1:1. Various embodiments are suitable for use in a passive hydraulic body-powered wearable robot, for example.
FILED Monday, August 26, 2019
APPL NO 16/551330
ART UNIT 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 66/432 (20130101)

Positive-displacement Machines for Liquids; Pumps
F04B 45/0736 (20130101) Original (OR) Class
F04B 53/02 (20130101)
F04B 53/143 (20130101)

Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for
F15B 15/10 (20130101)

Pistons; Cylinders; Sealings
F16J 3/02 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49877 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300515 Lew et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Matthew Lew (St. Louis, Missouri);  Arye Nehorai (St. Louis, Missouri);  Hesamaldin Mazidisharfabadi (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Matthew Lew (St. Louis, Missouri);  Arye Nehorai (St. Louis, Missouri);  Hesamaldin Mazidisharfabadi (St. Louis, Missouri)
ABSTRACT Systems and methods assessing the accuracy of at least one localization from a single molecule localization microscopy (SMLM) dataset containing a plurality of localizations are described. The systems and methods calculate a Wasserstein-induced flux (WIF) value indicative of a confidence in the accuracy of a localization within the SMLM data set.
FILED Thursday, July 30, 2020
APPL NO 16/943937
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6458 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 7/73 (20170101)
G06T 2207/10056 (20130101)
G06T 2207/30168 (20130101)
G06T 2207/30241 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300534 Potyrailo et al.
FUNDED BY
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
National Institute for Occupational Safety and Health (NIOSH)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) GENERAL ELECTRIC COMPANY (Niskayuna, New York)
INVENTOR(S) Radislav Alexandrovich Potyrailo (Niskayuna, New York);  Emad Andarawis Andarawis (Ballston Lake, New York);  Naresh Kesavan Rao (Clifton Park, New York)
ABSTRACT A monolithic gas-sensing chip assembly for sensing a gas analyte includes a sensing material to detect the gas analyte, a sensing system including a resistor-capacitor electrical circuit, and a heating element. A sensing circuit measures an electrical response of the sensing system to an alternating electrical current applied to the sensing system at (a) one or more different frequencies, or (b) one or more different resistor-capacitor configurations of the system. One or more processors control a low detection range of the system to the gas, a high detection range of the system to the gas, a linearity of a response of the system to the gas, a dynamic range of measurements of the gas by the system, a rejection of interfering gas analytes by the system, a correction for aging or poisoning of the system, or a rejection of ambient interferences that may affect the electrical response of the system.
FILED Friday, September 06, 2019
APPL NO 16/562611
ART UNIT 2867 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/123 (20130101) Original (OR) Class
G01N 27/226 (20130101)
G01N 27/228 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300565 Newman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) MOREHOUSE SCHOOL OF MEDICINE (Atlanta, Georgia)
ASSIGNEE(S) MOREHOUSE SCHOOL OF MEDICINE (Atlanta, Georgia)
INVENTOR(S) Gale W. Newman (Duluth, Georgia);  Sam Anyanwu (Atlanta, Georgia)
ABSTRACT A method for diagnosing hepatitis virus infection or a hepatitis disease condition in a subject based on hepatitis virus-associated biomarkers present on exosomes in a bodily fluid sample from the subject is disclosed. Also disclosed are a method for monitoring the course of a hepatitis virus infection or a hepatitis disease condition in a subject and a method for monitoring effectiveness of treatment to a subject with an anti-hepatitis virus agent based on hepatitis virus-associated biomarkers present on exosomes in bodily fluid samples from the subject, as well as a kit for diagnosing hepatitis virus infection and/or a hepatitis disease condition in a subject based on hepatitis virus-associated biomarkers on exosomes in bodily fluid samples from the subject.
FILED Monday, October 14, 2019
APPL NO 16/601178
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/70 (20130101)
C12Q 1/703 (20130101)
C12Q 1/706 (20130101)
C12Q 1/707 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/40 (20130101)
G01N 33/493 (20130101)
G01N 33/576 (20130101)
G01N 33/6893 (20130101)
G01N 33/56983 (20130101)
G01N 33/56988 (20130101) Original (OR) Class
G01N 2333/02 (20130101)
G01N 2333/10 (20130101)
G01N 2333/161 (20130101)
G01N 2333/162 (20130101)
G01N 2333/163 (20130101)
G01N 2333/186 (20130101)
G01N 2800/52 (20130101)
G01N 2800/56 (20130101)
G01N 2800/347 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300567 Weiss et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  THE FLINDERS UNIVERSITY OF SOUTH AUSTRALIA (Bedford Park, Australia)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  The Flinders University of South Australia (, None)
INVENTOR(S) Gregory A. Weiss (Irvine, California);  Joshua Britton (Irvine, California);  Colin L. Raston (South Australia, Australia)
ABSTRACT There are provided, inter alia, methods for reacting an enzyme and its substrate, methods for purifying a protein and an enzyme reactor and its use thereof.
FILED Wednesday, August 24, 2016
APPL NO 15/754797
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 1/22 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/14 (20130101)
C12N 9/96 (20130101)
C12N 11/00 (20130101)
C12N 13/00 (20130101)

Enzymes
C12Y 301/03001 (20130101)
C12Y 301/04001 (20130101)
C12Y 302/01023 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 31/10 (20130101)
G01N 33/573 (20130101) Original (OR) Class
G01N 2203/0055 (20130101)
G01N 2400/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300576 Sierks et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Michael Sierks (Fort McDowell, Arizona);  Stephanie Williams (Phoenix, Arizona)
ABSTRACT Disclosed are diagnostics for neurodegenerative diseases, and in particular to design ankyrin repeat protein (DARPins) reagents that distinguish Alzheimer's disease (AD) from Parkinson's disease (PD). Methods of diagnosing, monitoring treatment efficacy and developing treatments for neurodegenerative diseases, such as AD and PD are disclosed based upon the use of the AD or PD specific DARPins.
FILED Wednesday, January 29, 2020
APPL NO 16/776218
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/4711 (20130101)
C07K 2318/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6896 (20130101) Original (OR) Class
G01N 2800/2821 (20130101)
G01N 2800/2835 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300640 Dmochowski et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Ivan J. Dmochowski (Philadelphia, Pennsylvania);  Yanfei Wang (Boston, Massachusetts);  Benjamin W. Roose (Philadelphia, Pennsylvania);  Serge Zemerov (Cherry Hill, New Jersey);  Zhuangyu Zhao (Philadelphia, Pennsylvania)
ABSTRACT The present invention relates to compositions and methods using protein reporters as imaging agents in 129Xe NMR and MRI applications. It is described that bla and MBP are genetically-encoded proteins that induce a detectable chemical shift during 129Xe NMR, allowing for use as protein reporters in research and clinical applications.
FILED Tuesday, March 13, 2018
APPL NO 15/919566
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0008 (20130101)
A61K 49/14 (20130101)
A61K 49/0056 (20130101)
A61K 49/183 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 23/0005 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/62 (20130101)
G01R 33/282 (20130101) Original (OR) Class
G01R 33/5601 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 50/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300774 Dickensheets et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) MONTANA STATE UNIVERSITY (Bozeman, Montana);  MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S) MONTANA STATE UNIVERSITY (Bozeman, Montana);  MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York)
INVENTOR(S) David Dickensheets (Dozeman, Montana);  Milind Rajadhyaksha (New York, New York)
ABSTRACT Handheld devices and methods that integrate wide-field dermoscopy with reflectance confocal microscopy for non-invasive simultaneous capture of wide-field color images of the skin surface and images of the sub-surface cellular structure.
FILED Saturday, February 11, 2017
APPL NO 16/077352
ART UNIT 2872 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0068 (20130101)
A61B 5/0075 (20130101)
A61B 5/0077 (20130101)
A61B 5/444 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/02 (20130101)
G02B 21/06 (20130101)
G02B 21/0008 (20130101)
G02B 21/0028 (20130101)
G02B 21/0036 (20130101)
G02B 21/361 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11301993 Rose et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) The Schepens Eye Research Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) The Schepens Eye Research Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Dylan J. Rose (Medford, Massachusetts);  Daniel R. Saunders (Boston, Massachusetts);  Russell L. Woods (Boxborough, Massachusetts)
ABSTRACT The current subject matter relates to rehabilitation using a content guide for viewing video, for example as a vision rehabilitation aid for individuals with hemianopia or as a rehabilitation aid for individuals with attention disorders. The current subject matter includes providing video in which a region of interest of the image is specified with a marker, referred to herein as a content guide. The content guide can include a circle surrounding the region of interest. By providing video with a content guide to direct viewers to a region of interest in the video, information acquisition by the viewers is improved. Such an approach can aid individuals with vision deficits or attention disorders. The current subject matter can also be used as a therapy for spatial neglect. Related apparatus, systems, techniques and articles are also described.
FILED Saturday, February 17, 2018
APPL NO 16/475665
ART UNIT 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/163 (20170801)
A61B 5/742 (20130101)
A61B 5/4833 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class
G06T 2207/10016 (20130101)
G06T 2207/10024 (20130101)
G06T 2207/30041 (20130101)
G06T 2207/30204 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11301997 Majeed et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Siemens Healthcare GmbH (Erlangen, Germany);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland)
ASSIGNEE(S) Siemens Healthcare GmbH (Erlangen, Germany);  The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Waqas Majeed (Ellicott City, Maryland);  Himanshu Bhat (Newton, Massachusetts);  Rainer Schneider (Erlangen, Germany);  Adrienne Campbell (Bethesda, Maryland)
ABSTRACT A method for phase correction in proton resonance frequency (PRF) thermometry application includes acquiring a series of magnetic resonance (MR) images comprising a first MR image and plurality of subsequent MR images depicting an anatomical area of interest. The MR images are acquired while tissue in the anatomical area of interest is undergoing a temperature change. Each subsequent MR image is registered to the first MR image to yield a plurality of registered images. A plurality of basis images are computed from the registered images using Principal Component Analysis (PCA). The basis images are used to remove motion-related phase changes from a second series of MR images, thereby yielding a motion corrected second series of MR images. One or more temperature difference maps are generated that depict a relative temperature change for the tissue in the anatomical area of interest based on the motion corrected second series.
FILED Wednesday, April 15, 2020
APPL NO 16/849313
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/015 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class
G06T 7/38 (20170101)
G06T 7/215 (20170101)
G06T 2207/10088 (20130101)
G06T 2207/20182 (20130101)
G06T 2207/20201 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11302003 Liu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Fang Liu (Madison, Wisconsin);  Hyungseok Jang (Madison, Wisconsin);  Richard Kijowski (Verona, Wisconsin);  Tyler Bradshaw (Madison, Wisconsin);  Alan McMillan (Madison, Wisconsin)
ABSTRACT The present disclosure includes systems and methods for creating positron emission tomography (PET) images. The method includes receiving at least one PET image of a subject created from PET data acquired from the subject, creating an attenuation correction map using the at least one PET image, and reconstructing PET data using the attenuation correction map and the at least one PET image to generate an attenuation corrected PET image.
FILED Thursday, October 26, 2017
APPL NO 15/795219
ART UNIT 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 5/001 (20130101)
G06T 5/50 (20130101)
G06T 7/0014 (20130101) Original (OR) Class
G06T 11/008 (20130101)
G06T 2207/10104 (20130101)
G06T 2207/10124 (20130101)
G06T 2207/30004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11302043 Camino et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Oregon Health and Science University (Portland, Oregon)
ASSIGNEE(S) Oregon Health and Science University (Portland, Oregon)
INVENTOR(S) Acner Camino (Portland, Oregon);  David Huang (Portland, Oregon);  Yali Jia (Portland, Oregon)
ABSTRACT Disclosed herein are methods and systems for automated detection of shadow artifacts in optical coherence tomography (OCT) and/or OCT angiography (OCTA). The shadow detection includes applying a machine-learning algorithm to the OCT dataset and the OCTA dataset to detect one or more shadow artifacts in the sample. The machine-learning algorithm is trained with first training data from first training samples that include manufactured shadows and no perfusion defects and second training data from second training samples that include perfusion defects and no manufactured shadows. The shadow artifacts in the OCTA dataset and/or OCT dataset may be suppressed to generate a shadow-suppressed OCTA dataset and/or a shadow-suppressed OCT dataset, respectively. Other embodiments may be described and claimed.
FILED Thursday, February 27, 2020
APPL NO 16/803629
ART UNIT 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/102 (20130101)
A61B 5/0261 (20130101)
A61B 5/7203 (20130101)
A61B 5/7264 (20130101)

Image Data Processing or Generation, in General
G06T 7/0016 (20130101)
G06T 11/008 (20130101) Original (OR) Class
G06T 2207/10101 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/30104 (20130101)
G06T 2211/404 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11302422 Califano et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Andrea Califano (New York, New York);  Mukesh Bansal (New York, New York);  Yishai Shimoni (New York, New York)
ABSTRACT Techniques to identify a mechanism of action of a compound using network dysregulation are disclosed herein. An example method can include selecting at least a first interaction involving at least a first gene, determining a first n-dimensional probability density of gene expression levels for the first gene and one or more genes in a control state, determining a second n-dimensional probability density of gene expression levels for the first gene and one or more genes following treatment using at least one compound, estimating changes between the first probability density and the second probability density, and determining whether the estimated changes are statistically significant.
FILED Monday, May 11, 2015
APPL NO 15/305006
ART UNIT 3619 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 5/00 (20190201)
G16B 5/20 (20190201)
G16B 35/00 (20190201)
G16B 40/00 (20190201)

Computational Chemistry; Chemoinformatics; Computational Materials Science
G16C 20/10 (20190201) Original (OR) Class
G16C 20/60 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11302448 Jain et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Vignet Incorporated (Fairfax, Virginia)
ASSIGNEE(S) VigNet Incorporated (Fairfax, Virginia)
INVENTOR(S) Praduman Jain (Fairfax, Virginia);  Josh Schilling (Salem, Oregon);  Dave Klein (Oakton, Virginia)
ABSTRACT Methods, systems, and apparatus, including computer programs encoded on computer-storage media, for machine learning to select digital therapeutics. In some implementations, a machine learning model is trained to generate scores that indicate the level of applicability of different digital therapeutics based on input data for a person. A computer system monitors health of an individual using surveys and sensor measurements. The computer system identifies one or more signs or symptoms of a disease based on the monitoring data for the individual. The computer system uses output of the machine learning model to select a digital therapeutic intervention for the user. The computer system cause one or more devices to deliver the selected digital therapeutic intervention to the individual, monitor a response of the individual to the selected digital therapeutic intervention, and adjust characteristics of the digital therapeutic intervention based on the monitored response.
FILED Wednesday, June 23, 2021
APPL NO 17/355717
ART UNIT 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 50/70 (20180101)
G16H 50/80 (20180101) Original (OR) Class

Wireless Communication Networks
H04W 4/029 (20180201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11303592 Hsu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
NIH Office of the Director (NIHOD)
APPLICANT(S) Salk Institute for Biological Studies (La Jolla, California)
ASSIGNEE(S) Salk Institute for Biological Studies (La Jolla, California)
INVENTOR(S) Patrick D. Hsu (San Francisco, California);  Silvana Konermann (Menlo Park, California)
ABSTRACT Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.
FILED Monday, June 21, 2021
APPL NO 17/352579
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/85 (20130101)
C12N 15/102 (20130101)
C12N 15/113 (20130101)
C12N 15/8201 (20130101)
C12N 15/8213 (20130101)
C12N 2310/16 (20130101)
C12N 2310/20 (20170501)
C12N 2310/3519 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/08 (20130101)
H04L 9/30 (20130101)
H04L 45/745 (20130101)
H04L 51/08 (20130101)
H04L 51/12 (20130101) Original (OR) Class
H04L 51/14 (20130101)
H04L 51/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11303593 Hsu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
NIH Office of the Director (NIHOD)
APPLICANT(S) Salk Institute for Biological Studies (La Jolla, California)
ASSIGNEE(S) Salk Institute for Biological Studies (La Jolla, California)
INVENTOR(S) Patrick D. Hsu (San Francisco, California);  Silvana Konermann (Menlo Park, California)
ABSTRACT Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.
FILED Monday, June 21, 2021
APPL NO 17/352590
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/85 (20130101)
C12N 15/102 (20130101)
C12N 15/113 (20130101)
C12N 15/8201 (20130101)
C12N 15/8213 (20130101)
C12N 2310/16 (20130101)
C12N 2310/20 (20170501)
C12N 2310/3519 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/08 (20130101)
H04L 9/30 (20130101)
H04L 45/745 (20130101)
H04L 51/08 (20130101)
H04L 51/12 (20130101) Original (OR) Class
H04L 51/14 (20130101)
H04L 51/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11303594 Hsu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
NIH Office of the Director (NIHOD)
APPLICANT(S) Salk Institute for Biological Studies (La Jolla, California)
ASSIGNEE(S) Salk Institute for Biological Studies (La Jolla, California)
INVENTOR(S) Patrick D. Hsu (San Francisco, California);  Silvana Konermann (Menlo Park, California)
ABSTRACT Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.
FILED Monday, June 21, 2021
APPL NO 17/352611
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/85 (20130101)
C12N 15/102 (20130101)
C12N 15/113 (20130101)
C12N 15/8201 (20130101)
C12N 15/8213 (20130101)
C12N 2310/16 (20130101)
C12N 2310/20 (20170501)
C12N 2310/3519 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/08 (20130101)
H04L 9/30 (20130101)
H04L 45/745 (20130101)
H04L 51/08 (20130101)
H04L 51/12 (20130101) Original (OR) Class
H04L 51/14 (20130101)
H04L 51/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11298231 Bachus et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) University of Utah Research Foundation (Salt Lake City, Utah);  Joseph A. Longo (Paradise Valley, Arizona)
ASSIGNEE(S) Joseph A. Longo (Paradise Valley, Arizona);  UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah)
INVENTOR(S) Kent N. Bachus (Salt Lake City, Utah);  Sujee Jeyapalina (Salt Lake City, Utah);  James Peter Beck (Salt Lake City, Utah);  Roy Bloebaum (Salt Lake City, Utah);  Jayant P. Agarwal (Salt Lake City, Utah);  Joseph A. Longo (Paradise Valley, Arizona);  Erik Kubiak (Salt Lake City, Utah);  Brian Mueller Holt (Topanga, California)
ABSTRACT An implant assembly for a long bone is adapted to support an exo-prosthesis. The assembly includes a stem, a subdermal component and a percutaneous post. The stem has a proximal end that is adapted to be received in a surgically prepared medullary canal of the long bone, and a distal end having a surface that is adapted to promote bone ingrowth. The subdermal component includes a proximal portion that is adapted for attachment to the distal end of the stem, and a fixation surface that is adapted to promote soft tissue fixation. The percutaneous post has a proximal end that is adapted to be attached to the subdermal component.
FILED Friday, April 12, 2019
APPL NO 16/383363
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/78 (20130101)
A61F 2/2814 (20130101) Original (OR) Class
A61F 2002/7887 (20130101)
A61F 2002/30576 (20130101)
A61F 2002/30594 (20130101)
A61F 2002/30604 (20130101)
A61F 2002/30784 (20130101)
A61F 2002/30879 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298447 Stewart et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Ian J. Stewart (Lodi, California);  Jeremy W. Cannon (Philadelphia, Pennsylvania)
ABSTRACT A carbon dioxide absorption medium. The absorption medium includes a plurality of hollow fibers and a plurality of binder particles. The hollow fibers have walls comprising a selectively permeable membrane that is configured to permit passage of gaseous carbon dioxide but not liquids. The plurality bind particles are dispersed between the hollow fibers and comprise an absorbent material configured to absorb gaseous carbon dioxide and to bind the carbon dioxide in a solid state.
FILED Monday, February 04, 2019
APPL NO 16/266193
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 1/3479 (20140204)
A61M 1/3486 (20140204) Original (OR) Class
A61M 1/3627 (20130101)
A61M 2202/0225 (20130101)
A61M 2205/3334 (20130101)
A61M 2205/3337 (20130101)

Separation
B01D 61/246 (20130101)
B01D 69/08 (20130101)
B01D 71/16 (20130101)
B01D 71/38 (20130101)
B01D 71/42 (20130101)
B01D 71/56 (20130101)
B01D 71/68 (20130101)
B01D 2313/44 (20130101)
B01D 2325/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298541 Kahana et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Michael Kahana (Merion Station, Pennsylvania);  Daniel S. Rizzuto (Philadelphia, Pennsylvania)
ABSTRACT A method for delivering electrical stimulation to alter a cognitive state of a user, the method comprising: monitoring a brain signal from the user via one or more intracranial electrodes implanted in the brain of the user while the user is presented with a stimulus; comparing the brain signal to a testing phase biomarker, wherein the testing phase biomarker is derived from a cognitive test performed on a contributor during a testing phase; delivering electrical stimulation to a brain of the user based on the comparing step to steer the brain of the user towards a high performance cognitive state.
FILED Thursday, September 12, 2019
APPL NO 16/569205
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/377 (20210101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0531 (20130101)
A61N 1/0534 (20130101)
A61N 1/36064 (20130101)
A61N 1/36067 (20130101)
A61N 1/36082 (20130101) Original (OR) Class
A61N 1/36135 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/40 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298561 Millenbaugh
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Bureau of Medicine and Surgery (BUMED)
Naval Medical Research Center (NMRC)
Naval Medical Research Unit San Antonio (NAMRU-SA)
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
Oak Ridge Institute for Science and Education (ORISE)
APPLICANT(S) The United States of America Represented by the Secretary of Navy (Silver Spring, Maryland)
ASSIGNEE(S) The United States of America As Represented by the Secretary of the Navy (Arlinton, Virginia)
INVENTOR(S) Nancy Millenbaugh (San Antonio, Texas)
ABSTRACT This application describes a method of using gold nanoparticle (GNP)-targeted pulsed laser technology to enhance antibiotic efficacy against multidrug resistant biofilms. The application also teaches a method for treating topic wound infection using GNP-targeted laser therapy combined with antibiotics treatments.
FILED Sunday, May 05, 2019
APPL NO 16/403564
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 41/0052 (20130101)
A61K 45/06 (20130101)
A61K 47/6835 (20170801)
A61K 47/6923 (20170801)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/062 (20130101) Original (OR) Class
A61N 5/0624 (20130101)
A61N 2005/067 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298689 Asenath-Smith et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) United States of America as Represented by The Secretary of The Army (Alexandria, Virginia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia)
INVENTOR(S) Emily Asenath-Smith (Hanover, New Hampshire);  Emma K Ambrogi (Hanover, New Hampshire)
ABSTRACT Disclosed are various combinations of three different metal-oxide photocatalysts with three different bandgaps that can be used to harvest multiple wavelengths of incident solar radiation and to thus efficiently degrade recalcitrant contaminants. The photocatalysts are from the class of transition metal oxides and are non-toxic compounds based on earth-abundant materials. In some embodiments, particles of the photocatalysts are formed to be greater in diameter than about 0.1 μm in order to make them easier to filter out after treating the contaminant. In some embodiments, the metal-oxide photocatalysts are zinc oxide which is ultraviolet active, hematite which is active in the visible spectrum, and copper oxide which is active in the near infrared spectrum. Various combinations in various embodiments achieve measured contaminant degradation rates greater than the sum of the degradation rates of the individual photocatalysts that make up the combination.
FILED Monday, August 20, 2018
APPL NO 16/105117
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 53/86 (20130101)
B01D 2255/802 (20130101)
B01D 2255/20738 (20130101)
B01D 2255/20761 (20130101)
B01D 2255/20792 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/80 (20130101) Original (OR) Class
B01J 23/745 (20130101)
B01J 35/004 (20130101)
B01J 35/026 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/30 (20130101)
C02F 1/32 (20130101)
C02F 1/725 (20130101)
C02F 2305/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299139 Shukla et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Oshkosh Defense, LLC (Oshkosh, Wisconsin)
ASSIGNEE(S) Oshkosh Defense, LLC (Oshkosh, Wisconsin)
INVENTOR(S) Deepak Shukla (Oshkosh, Wisconsin);  Rongjun Zhang (Neenah, Wisconsin);  Nader Nasr (Neenah, Wisconsin)
ABSTRACT A drive train for a vehicle includes a first electromagnetic device, a second electromagnetic device electrically coupled to the first electromagnetic device by an electrical power transmission system, and an engine coupled to the first electromagnetic device and configured to drive the first electromagnetic device to provide electrical energy. In all modes of operation where the engine drives the first electromagnetic device to provide the electrical energy, the first electromagnetic device operates without providing the electrical energy to an energy storage device.
FILED Friday, October 01, 2021
APPL NO 17/492081
ART UNIT 3655 — Material and Article Handling
CURRENT CPC
Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles
B60K 6/26 (20130101)
B60K 6/34 (20130101)
B60K 6/52 (20130101)
B60K 6/365 (20130101)
B60K 6/387 (20130101)
B60K 6/445 (20130101)
B60K 6/543 (20130101)

Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles
B60L 50/11 (20190201)

Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit
B60W 10/02 (20130101)
B60W 10/06 (20130101)
B60W 10/08 (20130101)
B60W 20/10 (20130101) Original (OR) Class
B60W 2510/06 (20130101)
B60W 2510/08 (20130101)
B60W 2510/081 (20130101)
B60W 2510/0604 (20130101)
B60W 2510/0638 (20130101)
B60W 2520/10 (20130101)
B60W 2710/06 (20130101)
B60W 2710/08 (20130101)
B60W 2710/021 (20130101)
B60W 2710/083 (20130101)
B60W 2710/0644 (20130101)
B60W 2710/0677 (20130101)

Indexing Scheme Relating to Aspects Cross-cutting Vehicle Technology
B60Y 2200/92 (20130101)
B60Y 2300/42 (20130101)
B60Y 2300/43 (20130101)
B60Y 2300/60 (20130101)
B60Y 2300/72 (20130101)
B60Y 2400/72 (20130101)
B60Y 2400/73 (20130101)

Gearing
F16H 1/28 (20130101)
F16H 3/72 (20130101)
F16H 3/727 (20130101)
F16H 3/728 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/62 (20130101)
Y02T 10/92 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 903/91 (20130101)
Y10S 903/93 (20130101)
Y10S 903/906 (20130101)
Y10S 903/914 (20130101)
Y10S 903/916 (20130101)
Y10S 903/918 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299259 Christensen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Aviation Applied Technology Directorate (AATD)
APPLICANT(S) Bell Textron Inc. (Fort Worth, Texas)
ASSIGNEE(S) Textron Innovations Inc. (Providence, Rhode Island)
INVENTOR(S) Kevin Thomas Christensen (Plano, Texas);  Hunter Barton Nelson (North Richland Hills, Texas);  Martin Wesley Shubert (Tall Timbers, Maryland);  Paul David Ruckel (Fort Worth, Texas)
ABSTRACT An exemplary method for controlling low speed flight of an aircraft having a controller receiving pilot input includes transitioning from a translational rate command (TRC) to a linear acceleration command (LAC) when the controller is displaced above a control transition displacement (CTD), and while in LAC holding speed when the controller is relaxed to CTD.
FILED Wednesday, January 29, 2020
APPL NO 16/775531
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Aeroplanes; Helicopters
B64C 15/12 (20130101)
B64C 19/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299428 Hunt et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Michael Hunt (Alexandria, Virginia);  Guillermo R. Villalobos (Springfield, Virginia);  Benjamin Rock (Rockville, Maryland);  Shyam S. Bayya (Ashburn, Virginia);  Woohong Kim (Washington, District of Columbia);  Ishwar D. Aggarwal (Waxhaw, North Carolina);  Bryan Sadowski (Falls Church, Virginia);  Jasbinder S. Sanghera (Ashburn, Virginia)
ABSTRACT The present invention provides a method for making a high strength, small grain size ceramic having a trans-granular fracture mode by rapid densification of a green body and subsequent cooling of the densified ceramic. The ceramic may include dislocations, defects, dopants, and/or secondary phases that are formed as a result of the process and resulting in stress fields capable of redirecting or arresting cracks within the material. This ceramic can maintain transparency from ultraviolet to mid-wave infrared.
FILED Thursday, April 27, 2017
APPL NO 15/498709
ART UNIT 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/50 (20130101)
C04B 35/64 (20130101)
C04B 35/443 (20130101)
C04B 35/505 (20130101) Original (OR) Class
C04B 35/638 (20130101)
C04B 35/4682 (20130101)
C04B 2235/77 (20130101)
C04B 2235/604 (20130101)
C04B 2235/608 (20130101)
C04B 2235/667 (20130101)
C04B 2235/786 (20130101)
C04B 2235/3208 (20130101)
C04B 2235/3215 (20130101)
C04B 2235/3222 (20130101)
C04B 2235/3224 (20130101)
C04B 2235/3225 (20130101)
C04B 2235/3236 (20130101)
C04B 2235/5409 (20130101)
C04B 2235/5445 (20130101)
C04B 2235/6025 (20130101)
C04B 2235/6027 (20130101)
C04B 2235/6562 (20130101)
C04B 2235/6567 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299560 Casalini et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Riccardo Casalini (Hyattsville, Maryland);  James Hemmer (Fribourg, Switzerland);  Brian Mason (Monterey, California)
ABSTRACT Disclosed is a method of: providing a solution having a solvent, a polybutadiene, and an acrylate; and functionalizing the polybutadiene with the diacrylate to produce an ionic polymer. The polymer may be useful as an additive manufacturing binder.
FILED Tuesday, February 04, 2020
APPL NO 16/781643
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 70/00 (20141201)
B33Y 80/00 (20141201)

Treatment or Chemical Modification of Rubbers
C08C 19/36 (20130101)
C08C 19/42 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299582 Martin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Brett D. Martin (Washington, District of Columbia);  Jawad Naciri (Arlington, Virginia);  Banahalli R. Ratna (Alexandria, Virginia)
ABSTRACT An interpenetrating network (IPN) polymer membrane material includes a soft polyurethane interspersed with a crosslinked conducting polymer. The material can be reversibly “switched” between its oxidized and reduced states by the application of a small voltage, ˜1 to 4 volts, thus modulating its diffusivity.
FILED Tuesday, April 28, 2020
APPL NO 16/860330
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 61/126 (20130101) Original (OR) Class
C08G 81/00 (20130101)
C08G 2261/70 (20130101)
C08G 2261/122 (20130101)
C08G 2261/126 (20130101)
C08G 2261/514 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/127 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299638 Haddad et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Timothy S. Haddad (Lancaster, California);  Joseph M. Mabry (Lancaster, California);  Sean Ramirez (Lancaster, California)
ABSTRACT A method of forming a hydrophobic and oleophobic surface. The method including spin coating an F-POSS with 3,3-dichloro-1,1,1,2,2,-pentafluoropropane/1,3-dichloro-1,1,2,2,3-pentafluoropropane onto an inert surface. The F-POSS has a structure: Each Rf represents a nonreactive, fluorinated organic group, R1 represents a first monovalent organic group comprising at least two carbon atoms, and R2 represents hydrogen or a second monovalent organic group comprising at least two carbon atoms. The F-POSS with 3,3-dichloro-1,1,1,2,2,-pentafluoropropane/1,3-dichloro-1,1,2,2,3-pentafluoropropane are then dried on the inert surface.
FILED Friday, December 20, 2019
APPL NO 16/722770
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 5/083 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 7/21 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 77/045 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/549 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/1662 (20130101) Original (OR) Class
C09D 7/63 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299729 Badran et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Ahmed Hussein Badran (Dorchester, Massachusetts);  David R. Liu (Lexington, Massachusetts)
ABSTRACT Strategies, reagents, methods, and systems for modulating the mutation rate in cells are provided herein. The strategies, reagents, methods, and systems are broadly applicable for the modulation of mutation rates in cells where high mutation rates and/or control over a broad range of mutation rates is desired, for example, in the context of diversifying a nucleic acid sequence or a plurality of such sequences within a population of cells, for the generation of diversified nucleic acid libraries, and for directed evolution of nucleic acids and encoded products.
FILED Friday, April 15, 2016
APPL NO 15/567312
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/48 (20130101)
C12N 9/1241 (20130101)
C12N 15/70 (20130101)
C12N 15/102 (20130101) Original (OR) Class
C12N 15/1058 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299770 Samusik et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California)
INVENTOR(S) Nikolay Samusik (Mountain View, California);  Garry P. Nolan (Redwood City, California);  Yury Goltsev (Stanford, California)
ABSTRACT A method for analyzing planar sample is provided. In some cases the method comprises: (a) incubating the planar sample with a capture agent that is linked to an oligonucleotide, wherein the capture agent specifically binds to complementary sites in the planar sample; (b) reading a fluorescent signal caused by extension of a primer that is hybridized to the oligonucleotide, using fluorescence microscopy. Several implementations of the method, and multiplexed versions of the same, are also provided.
FILED Friday, January 04, 2019
APPL NO 16/240463
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6804 (20130101)
C12Q 1/6804 (20130101)
C12Q 1/6804 (20130101)
C12Q 1/6818 (20130101) Original (OR) Class
C12Q 2565/101 (20130101)
C12Q 2565/1015 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299776 Ellington et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Aeronautics and Space Administration (NASA)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Andrew Ellington (Austin, Texas);  Cheulhee Jung (Austin, Texas);  Sheng Cai (Zhejiang, China PRC);  Sanchita Bhadra (Austin, Texas);  John N. Milligan (Austin, Texas);  Daniel Garry (Austin, Texas);  Raghav Shroff (Austin, Texas)
ABSTRACT Disclosed are compositions and methods for nucleic acid amplification and detection. Specifically, disclosed herein are compositions and methods that allow for amplification of nucleic acids at a wide variety of temperatures. This includes a polymerase which is thermostable at high temperatures, and a method of amplification that can be conducted at relatively low temperatures.
FILED Thursday, May 10, 2018
APPL NO 16/612020
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1252 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/6853 (20130101) Original (OR) Class
C12Q 2521/101 (20130101)
C12Q 2525/301 (20130101)
C12Q 2527/101 (20130101)
C12Q 2531/101 (20130101)
C12Q 2537/1373 (20130101)
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300049 Dierksmeier et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Aviation Applied Technology Directorate (AATD)
APPLICANT(S) Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana)
ASSIGNEE(S) ROLLS-ROYCE NORTH AMERICAN TECHNOLOGIES INC. (Indianapolis, Indiana)
INVENTOR(S) Douglas David Dierksmeier (Franklin, Indiana);  Douglas Boyd (Indianapolis, Indiana);  Douglas J. Snyder (Carmel, Indiana);  Graham Burkholder (Avon, Indiana);  William Barry Bryan (Indianapolis, Indiana)
ABSTRACT A system includes a housing for a gas turbine engine, and a fan disposed in the housing to rotate coaxially with a gas turbine included in the housing. The system also includes an inlet guide vane disposed in the housing in axial alignment with the fan and configured to have an open position where a first flow of air is received by the fan through the inlet guide vane, and a closed position where airflow through the inlet guide vane is obstructed. The system further includes a heat exchanger disposed in a supply passage in fluid communication with a second flow of air received by the fan. The second flow of air is received by the fan via the supply passage with the inlet guide vane in the open position or in the closed position.
FILED Monday, March 09, 2020
APPL NO 16/813491
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/10 (20130101)
F02C 7/18 (20130101)
F02C 7/042 (20130101) Original (OR) Class
F02C 9/20 (20130101)

Jet-propulsion Plants
F02K 3/06 (20130101)
F02K 3/12 (20130101)
F02K 3/077 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/36 (20130101)
F05D 2260/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300145 Fletcher et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Nathan J Fletcher (Beavercreek, Ohio);  Christopher R Marks (Waynesville, Ohio)
ABSTRACT The systems and methods provided herein are directed to a stationary device for simulating the periodic unsteadiness typically produced by turbines in an air stream. A streamlined body includes a line of jets along its leading edge that pulses air at an angle against the air stream, and a separate line of jets along its trailing edge to expel a sustained air flow in the same direction as the air stream.
FILED Friday, October 30, 2020
APPL NO 17/086242
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids
F15D 1/008 (20130101) Original (OR) Class
F15D 1/08 (20130101)
F15D 1/12 (20130101)
F15D 1/0065 (20130101)
F15D 1/065 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300370 Migliaccio et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Christopher Phillip Migliaccio (University Park, Maryland);  Nathan Scott Lazarus (Bethesda, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Christopher Phillip Migliaccio (University Park, Maryland);  Nathan Scott Lazarus (Bethesda, Maryland)
ABSTRACT A method and apparatus for heat transfer. In some embodiments, a heat transfer apparatus includes a body defining an inner volume; an inlet coupled to a vapor source; a coolant channel extending through the heat transfer apparatus; a condensing surface on which a vapor condenses, wherein the condensing surface is configured to cause the vapor to form as one or more drops on the condensing surface; and an actuator configured to excite the one or more drops at a resonant frequency of the one or more drops to remove the one or more drops from the condensing surface.
FILED Monday, December 29, 2014
APPL NO 14/583830
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 13/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300389 Han
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Armaments Center (CCDC AC)
APPLICANT(S) U.S. Army Combat Capabilities Development Command Armaments Center (Dover, New Jersey)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Seungeuk Han (Highland Park, New Jersey)
ABSTRACT A rear slip base plate for a round carrying a guidance and control unit payload, which round is launched from a rifled launch tube. To prevent the guidance and control unit payload from also being rapidly spun with the round, the slip base plate unit mechanically isolates the guidance and control unit payload from the round spin rate.
FILED Tuesday, March 19, 2019
APPL NO 16/357585
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 10/02 (20130101) Original (OR) Class
F42B 14/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300390 Sesler et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Dynamic Structures and Materials, LLC (Franklin, Tennessee)
ASSIGNEE(S) Dynamic Structures and Materials, LLC (Franklin, Tennessee)
INVENTOR(S) Joshua J. Sesler (Franklin, Tennessee);  Bert K. McMahan (Brentwood, Tennessee);  Mark C. McMahan (Nashville, Tennessee)
ABSTRACT A control surface deployment apparatus having a base part, a drive actuator operably installed adjacent to the base part and having a drive actuator shaft extending beyond the base part, a knuckle part installed on the drive actuator shaft so as to selectively rotate therewith, a hinge part pivotally installed on the knuckle part as through a hinge pin, a fin rigidly installed on the hinge part so as to extend away from the knuckle part, and a spring biasing element configured to pivotally bias the hinge part relative to the knuckle part.
FILED Thursday, February 28, 2019
APPL NO 16/288978
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 10/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300571 Clinton et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
APPLICANT(S) Meso Scale Technologies, LLC (Gaithersburg, Maryland)
ASSIGNEE(S) Meso Scale Technologies, LLC. (Rockville, Maryland)
INVENTOR(S) Charles M. Clinton (Clarksburg, Maryland);  Eli N. Glezer (Chevy Chase, Maryland);  Bandele Jeffrey-Coker (Darnestown, Maryland);  Sandor L. Kovacs (Middletown, Maryland);  Sudeep M. Kumar (Gaithersburg, Maryland);  George Sigal (Rockville, Maryland);  Carl Stevens (Silver Spring, Maryland);  Michael Vock (Loveland, Ohio)
ABSTRACT We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
FILED Thursday, May 23, 2019
APPL NO 16/420724
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5085 (20130101)
B01L 3/50255 (20130101)

Applying Closure Members to Bottles Jars, or Similar Containers; Opening Closed Containers
B67B 7/24 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/66 (20130101)
G01N 21/6452 (20130101)
G01N 33/582 (20130101) Original (OR) Class
G01N 33/5302 (20130101)
G01N 35/028 (20130101)
G01N 35/109 (20130101)
G01N 35/1002 (20130101)
G01N 35/1011 (20130101)
G01N 35/1079 (20130101)
G01N 35/1081 (20130101)
G01N 2035/0405 (20130101)
G01N 2035/0425 (20130101)
G01N 2035/1025 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 83/9314 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300616 Fasig et al.
FUNDED BY
Department of Defense (DOD)
Non-Profit Organization (NPO)
Mayo Clinic (MAYO)
Mayo Foundation for Medical Education and Research (MFMER)
Special Purpose Processor Development Group (SPPDG)
National Security Agency (NSA)
APPLICANT(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Jonathan L. Fasig (Rochester, Minnesota);  Christopher K. White (Rochester, Minnesota);  Chad M. Smutzer (Rochester, Minnesota);  Michael J. Degerstrom (Rochester, Minnesota)
ABSTRACT A technique for non-invasively assessing current drawn by a device under test (DUT) by monitoring a supply voltage to the DUT. Frequency data for the DUT may be generated and used to form a current estimation model. First and second voltages are simultaneously measured using first and second test probes electrically connected to the DUT, while the first test probe is connected at a current source, and while the second test probe is connected at a DUT load that is configured to draw current from the current source. The current drawn by the DUT is then assessed by applying the current estimation model to the measured first and second voltages. In one case, the current drawn by the DUT is estimated without insertion of a circuit component into the DUT or extraction of a circuit conductor from the DUT.
FILED Wednesday, July 11, 2018
APPL NO 16/629518
ART UNIT 2851 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/31924 (20130101)
G01R 31/318357 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300651 Patel et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) The United States of America, as Represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Yogeshkumar M. Patel (Ventura, California);  Robert Barreto (Ventura, California);  Christopher F. Calderon (Oxnard, California);  Nathan Andrew Alday (Ventura, California);  Andrew Hamilton Kay (Lynn Haven, Florida);  Paul Nelson (Oxnard, California);  Donald Patrick Hilliard (Camarillo, California);  Dean Lucian Mensa (Ventura, California);  Leroy Francis Mumma (Oxnard, California)
ABSTRACT A system for augmenting 360-degree aspect monostatic radar cross section of an aircraft. The system may comprise a pair of pods mountable on opposing wing tips of an aircraft and each having a pod housing with an elongate body tapering forwardly to a nose and rearwardly to a tail. Each pod may comprise a forward SDL disposed within the nose, a rear SDL disposed within the tail, and a pair of mid-body SDLs disposed within a mid-section of the pod housing. The SDLs may be arranged within the pods to reflect radiation and provide coverage around the aircraft over a region of about 360 azimuth degrees. Each SDL may comprise radar absorbing material located on an interior reflective surface, and portions of the elongate bodies may be constructed of radome material. The SDLs may be Luneburg lens having diameters of at least approximately 8-inches.
FILED Thursday, March 14, 2019
APPL NO 16/353462
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/027 (20210501)
G01S 7/032 (20130101) Original (OR) Class
G01S 13/75 (20130101)
G01S 13/933 (20200101)

Antennas, i.e Radio Aerials
H01Q 15/08 (20130101)
H01Q 15/23 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300754 Patterson et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) HRL LABORATORIES, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Pamela R. Patterson (Los Angeles, California);  Florian G. Herrault (Thousand Oaks, California);  Oleg M. Efimov (Thousand Oaks, California);  Keyvan R. Sayyah (Santa Monica, California)
ABSTRACT A micro-optical bench includes a substrate having a multi-layer trench and a micro-lens aligned by and mounted to the substrate in the multi-layer trench.
FILED Wednesday, April 22, 2020
APPL NO 16/855318
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 7/003 (20130101)
G02B 7/025 (20130101) Original (OR) Class
G02B 27/62 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300968 Pierson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Alyssa Pierson (Somerville, Massachusetts);  Wilko Schwarting (Cambridge, Massachusetts);  Sertac Karaman (Cambridge, Massachusetts);  Daniela L. Rus (Weston, Massachusetts)
ABSTRACT A method is disclosed for use in a planning agent, the method including: identifying a first agent in a vicinity of the planning agent; identifying a location of the first agent and a velocity of the first agent; calculating a set of occupancy costs for the first agent, each occupancy cost in the set of occupancy costs being associated with a different respective location in the vicinity of the planning agent, each occupancy cost in the set of occupancy costs being calculated at least in part based on a cost function that depends on the location of the first agent and the velocity of the first agent; and changing at least one of speed or direction of travel of the planning agent based on the set of occupancy costs.
FILED Friday, February 22, 2019
APPL NO 16/283158
ART UNIT 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Systems for Controlling or Regulating Non-electric Variables
G05D 1/0214 (20130101)
G05D 1/0223 (20130101) Original (OR) Class
G05D 2201/0213 (20130101)

Electric Digital Data Processing
G06F 16/29 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11301563 Huang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
Mitigating APT Reasoning with Provenance in Large Enterprise Networks (MARPLE)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Heqing Huang (Mahwah, New Jersey);  Taesung Lee (Ridgefield, Connecticut);  Ian M. Molloy (Chappaqua, New York);  Zhongshu Gu (Ridgewood, New Jersey);  Jialong Zhang (San Jose, California);  Josyula R. Rao (Briarcliff Manor, New York)
ABSTRACT Mechanisms are provided for detecting abnormal system call sequences in a monitored computing environment. The mechanisms receive, from a computing system resource of the monitored computing environment, a system call of an observed system call sequence for evaluation. A trained recurrent neural network (RNN), trained to predict system call sequences, processes the system call to generate a prediction of a subsequent system call in a predicted system call sequence. Abnormal call sequence logic compares the subsequent system call in the predicted system call sequence to an observed system call in the observed system call sequence and identifies a difference between the predicted system call sequence and the observed system call sequence based on results of the comparing. The abnormal call sequence logic generates an alert notification in response to identifying the difference.
FILED Wednesday, March 13, 2019
APPL NO 16/351718
ART UNIT 2494 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/554 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11301757 Alpert et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Charles J. Alpert (Austin, Texas);  Pallab Datta (San Jose, California);  Myron D. Flickner (San Jose, California);  Zhou Li (Austin, Texas);  Dharmendra S. Modha (San Jose, California);  Gi-Joon Nam (Austin, Texas)
ABSTRACT Embodiments of the present invention relate to providing fault-tolerant power minimization in a multi-core neurosynaptic network. In one embodiment of the present invention, a method of and computer program product for fault-tolerant power-driven synthesis is provided. Power consumption of a neurosynaptic network is modeled as wire length. The neurosynaptic network comprises a plurality of neurosynaptic cores connected by a plurality of routers. At least one faulty core of the plurality of neurosynaptic cores is located. A placement blockage is modeled at the location of the at least one faulty core. A placement of the neurosynaptic cores is determined by minimizing the wire length.
FILED Tuesday, November 26, 2019
APPL NO 16/696968
ART UNIT 2148 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11302786 Wong et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories LLC (Malibu, California)
INVENTOR(S) Joel C. Wong (Simi Valley, California);  Jeong-Sun Moon (Malibu, California);  Robert M. Grabar (Malibu, California);  Michael T. Antcliffe (Malibu, California)
ABSTRACT A method of fabricating a gate with a mini field plate includes forming a dielectric passivation layer over an epitaxy layer on a substrate, coating the dielectric passivation layer with a first resist layer, etching the first resist layer and the dielectric passivation layer to form a first opening in the dielectric passivation layer, removing the first resist layer, and forming a tri-layer gate having a gate foot in the first opening, a gate neck extending from the gate foot, and a gate head extending from the gate neck. The gate foot has a first width, and the gate neck has a second width that is wider than the first width. The gate neck extends for a length over the dielectric passivation layer on both sides of the first opening. The gate head has a third width wider than the second width of the gate neck.
FILED Monday, January 27, 2020
APPL NO 16/773090
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/765 (20130101)
H01L 21/28587 (20130101)
H01L 21/31111 (20130101)
H01L 21/31144 (20130101)
H01L 29/205 (20130101)
H01L 29/404 (20130101) Original (OR) Class
H01L 29/413 (20130101)
H01L 29/2003 (20130101)
H01L 29/7786 (20130101)
H01L 29/42316 (20130101)
H01L 29/66462 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11302855 Kocevski et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Vancho Kocevski (Chicago, Illinois);  Christopher M. Wolverton (Evanston, Illinois)
ABSTRACT A thermoelectric material may be composed of an isostructural pair of Heusler compounds, either a pair of full Heusler (FH) X2YZ compounds or a pair of half Heusler (HH) XYZ compounds. In the FH pair, a first compound of the pair may the formula (X1)2Y1Z1, wherein X1 is selected from Fe and Co; Y1 is selected from Ti, V, Nb, Hf, and Ta; and Z1 is selected from Al, Ga, Si, and Sn and a second compound of the pair has the formula (X2)2Y2Z2, wherein X2 is selected from Mn, Fe, Co, Ru, and Rh; Y2 is selected from Ti, V, Mn, Zr, Nb, Hf, and Ta; and Z2 is selected from Be, Al, Ga, Si, Ge and Sn. The first and second compounds of the pair may share two elements in common and have third elements which are different and are either isovalent or have a valency which differs by ±1. In the HH pair, a first compound of the pair may have the formula X1Y1Z1 wherein X1 is selected from Ni and Fe; Y1 is selected from Ti, V, and Nb; and Z1 is selected from Sn and Sb and a second compound of the pair has the formula X2Y2Z2 wherein X2 is selected from Fe, Ru and Pt; Y2 is selected from Ti, V, and Nb; and Z2 is selected from Sn and Sb. The first and second compounds of the pair may share two elements in common and have third elements which are different and are either isovalent or have a valency which differs by ±1. The thermoelectric material at room temperature may have a nanostructured two-phase form having a matrix phase composed of the first compound of the FH pair or the first compound of the HH pair and a nanostructured phase composed of the second compound of the FH pair or the second compound of the HH pair, respectively.
FILED Wednesday, March 13, 2019
APPL NO 16/351887
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 35/18 (20130101)
H01L 35/20 (20130101)
H01L 35/22 (20130101)
H01L 35/26 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11302862 Miesner
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) John E. Miesner (Fairfax, Virginia)
ABSTRACT Exemplary practice of the present invention provides a magnetostrictive actuator characterized by linear force output and uniform magnetic biasing. A center bias magnet combined with a flux transfer tube produces a uniform magnetic bias down the length of a magnetostrictive component. Depending on the inventive embodiment, the magnetostrictive component may include one magnetostrictive element or a pair of collinear magnetostrictive elements. A center bias magnet, in combination with a flux transfer tube, drives magnetic flux through the magnetostrictive component (e.g., a series of magnetostrictive rods) in opposite directions, while surrounding drive coils apply flux in the same direction through the magnetostrictive component. The net response is substantially linear with respect to the drive coil current. The flux transfer tube applies distributed magnetic flux to the magnetostrictive component at a rate that ensures uniform magnetic flux density down the length of the magnetostrictive component.
FILED Tuesday, February 09, 2021
APPL NO 17/171317
ART UNIT 2838 — Electrical Circuits and Systems
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 41/06 (20130101)
H01L 41/12 (20130101) Original (OR) Class

Electric Machines Not Otherwise Provided for
H02N 2/043 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11302881 Forrest et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Stephen R. Forrest (Ann Arbor, Michigan);  Noel C. Giebink (Downers Grove, Illinois)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Stephen R. Forrest (Ann Arbor, Michigan);  Noel C. Giebink (Downers Grove, Illinois)
ABSTRACT The present disclosure generally relates to organic photosensitive optoelectronic devices and polaron pair recombination dynamics to impact efficiency and open circuit voltages of organic solar cells. The present disclosure also relates, in part, to methods of making organic photosensitive optoelectronic devices comprising the same.
FILED Tuesday, May 03, 2011
APPL NO 13/099716
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/001 (20130101)
H01L 51/0046 (20130101)
H01L 51/0047 (20130101)
H01L 51/0054 (20130101)
H01L 51/0055 (20130101)
H01L 51/0078 (20130101)
H01L 51/0091 (20130101)
H01L 51/4253 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/549 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11303029 Zekios et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) Constantinos L. Zekios (Miami, Florida);  Stavros Georgakopoulos (Miami, Florida);  Muhammad Hamza (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Constantinos L. Zekios (Miami, Florida);  Stavros Georgakopoulos (Miami, Florida);  Muhammad Hamza (Miami, Florida)
ABSTRACT Antenna devices are provided, including tightly coupled arrays, transmitarrays, and reflectarrays. An antenna device can include a plurality of substrates each having an antenna element. The substrates can be provided in connected series or in an array. The substrates can be part of an origami array such that the entire array is foldable. The substrates can optionally be attached to a framework that can actuate the substrates to different configurations. By bending, folding, or otherwise repositioning the substrates/array, the electromagnetic characteristics of the antenna device can be easily reconfigured for the desired task.
FILED Friday, March 26, 2021
APPL NO 17/213645
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/08 (20130101)
H01Q 1/38 (20130101)
H01Q 9/285 (20130101)
H01Q 9/0414 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11303033 Bamford et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (, None)
INVENTOR(S) David J Bamford (Wakefield, Rhode Island);  Paul Medeiros (Middleboro, Massachusetts);  Douglas A Sasko (West Mystic, Connecticut)
ABSTRACT An adjustable antenna is provided with a linear central support defining a helical axis, and first and second support disks extending radially outward from the central support. The support disks are rotatable around the central support and the second support disk is translatable along the linear central support. An antenna element is coupled to the first and second support disks to define a helical path around the central support between the first and second support disks. An adjustment component is capable of translating one of the first and second support disks along the linear central support and of rotating at least one of the support disks around the central support to change the helical pitch of the antenna element.
FILED Tuesday, October 27, 2020
APPL NO 17/080888
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/362 (20130101)
H01Q 3/12 (20130101)
H01Q 11/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11303040 Stumme et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Anna Stumme (Washington, District of Columbia);  William Mark Dorsey (Ellicott City, Maryland);  John Logan (Fairfax, Virginia)
ABSTRACT Embodiments are directed configurations of antenna elements for conformal phased arrays (e.g., circular or cylindrical) to support either omnidirectional or directional high-gain beams. Antenna elements may be spaced about a circle or cylinder with a vertical and circumferential element spacing that is based on a wavelength of an operational frequency. Such a configuration of antenna elements enables easy scaling to different frequency bands and a straightforward extension from single-linear to dual-linear polarization. Furthermore, the antenna elements and their configurations enable conformal phased arrays to be formed as one integrated structure or with multiple modular structures.
FILED Thursday, May 07, 2020
APPL NO 16/869044
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 13/0208 (20130101)
H01Q 21/205 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11303281 Pasandi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
ASSIGNEE(S) University of Southern California (Los Angeles, California)
INVENTOR(S) Ghasem Pasandi (Los Angeles, California);  Massoud Pedram (Beverly Hills, California)
ABSTRACT An SFQ circuit system includes at least one SFQ block having a plurality of SFQ logic gates. Characteristically, at least a portion of the SFQ logic gates are arranged in series. The SFQ circuit system includes a timing system configured to provide a first set of inputs and collect a first set of outputs of the at least one SFQ block at a rate defined by a slow clock frequency while the SFQ logic gates are clocked at a fast clock frequency. Advantageously, the rate is sufficiently slow to allow the first set of inputs to propagate through all levels of the SFQ logic gates to produce the first set of outputs of the at least one SFQ block without colliding with a second set of inputs to the at least one SFQ block.
FILED Monday, April 05, 2021
APPL NO 17/221998
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101)

Pulse Technique
H03K 19/20 (20130101)
H03K 19/096 (20130101)
H03K 19/195 (20130101) Original (OR) Class
H03K 19/17744 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11303377 Giannakis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Georgios B. Giannakis (Minnetonka, Minnesota);  Xiaoli Ma (Auburn, Alabama)
ABSTRACT Techniques are described for carrier frequency offset (CFO) and channel estimation of orthogonal frequency division multiplexing (OFDM) transmissions over multiple-input multiple-output (MIMO) frequency-selective fading channels. A wireless transmitter forms blocks of symbols by inserting training symbols within two or more blocks of information-bearing symbols. The transmitter applies a hopping code to each of the blocks of symbols to insert a null subcarrier at a different position within each of the blocks of symbols, and a modulator outputs a wireless signal in accordance with the blocks of symbols. A receiver receives the wireless signal and estimates the CFO, and outputs a stream of estimated symbols based on the estimated CFO.
FILED Monday, May 18, 2020
APPL NO 16/876316
ART UNIT 2633 — Digital Communications
CURRENT CPC
Transmission
H04B 7/046 (20130101)
H04B 7/063 (20130101)
H04B 7/066 (20130101)
H04B 7/0413 (20130101)

Multiplex Communication
H04J 11/0063 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 5/0016 (20130101)
H04L 25/0202 (20130101)
H04L 25/0206 (20130101)
H04L 25/0228 (20130101)
H04L 25/0242 (20130101)
H04L 27/2607 (20130101)
H04L 27/2613 (20130101)
H04L 27/2626 (20130101)
H04L 27/2657 (20130101)
H04L 27/2671 (20130101)
H04L 27/2672 (20130101)
H04L 27/2675 (20130101)
H04L 27/2692 (20130101)
H04L 27/2695 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11303443 Kuai et al.
FUNDED BY
Department of Defense (DOD)
United States Special Operations Command (SOCOM)
APPLICANT(S) GBTI SOLUTION, INC. (McLean, Virginia)
ASSIGNEE(S) GBTI SOLUTIONS (McLean, Virginia)
INVENTOR(S) Wenming Kuai (Great Falls, Virginia);  Joshua Solomon Rappaport (Rockville, Maryland);  Fuzhen Li (Great Falls, Virginia)
ABSTRACT A method of performing a blockchain transaction includes partitioning a private key of an account into a first part, a second part, and a third part, using a processor. The method further includes delivering the first part to a user of the account via a network. The method further includes storing the second part on a first server in association with information about the end-user. The method further includes receiving the first part from the user via the network. The method further includes reconstructing the private key of the account using the first part and the second part. The method further includes performing the blockchain transaction using the account and the reconstructed private key.
FILED Tuesday, November 12, 2019
APPL NO 16/681031
ART UNIT 2435 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/085 (20130101)
H04L 9/321 (20130101)
H04L 9/0894 (20130101) Original (OR) Class
H04L 63/145 (20130101)
H04L 2209/38 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11303584 Hall et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Honeywell International Inc. (Morris Plains, New Jersey)
ASSIGNEE(S) Honeywell International Inc. (Charlotte, North Carolina)
INVENTOR(S) Brendan Hall (Eden Prairie, Minnesota);  Kevin Raymond Driscoll (Maple Grove, Minnesota)
ABSTRACT A network includes a plurality of nodes and a plurality of links communicatively coupling each of the nodes to at least one respective adjacent node via a first communication channel and to another respective adjacent node via a second communication channel. The nodes and links have a braided ring topology. First and second nodes of the plurality of nodes source data, are adjacent nodes, and at least one is a source node. The first node sends a first communication to the second node via a third node that is adjacent the first node and via a fourth node that is adjacent the second node. The second node sends a second communication to the first node via the third node and via the fourth node. At least one of the first and second nodes terminates transmission of the first and second communications when the first and second communications do not match.
FILED Friday, October 11, 2019
APPL NO 16/600385
ART UNIT 2473 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 12/422 (20130101)
H04L 45/24 (20130101)
H04L 49/555 (20130101)
H04L 49/557 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11303793 Cossairt et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Northwestern University (Evanston, Illinois);  Peking University (Beijing, China PRC)
ASSIGNEE(S) Northwestern University (Evanston, Illinois);  Peking University (Beijing, China PRC)
INVENTOR(S) Oliver Strider Cossairt (Evanston, Illinois);  Boxin Shi (Beijing, China PRC);  Zihao Wang (Evanston, Illinois);  Peiqi Duan (Beijing, China PRC);  Aggelos K. Katsaggelos (Chicago, Illinois);  Tiejun Huang (Beijing, China PRC)
ABSTRACT An imaging system includes an event camera configured to capture a first image of a scene. The system also includes a shutter camera collocated with the event camera, where the shutter camera is configured to capture a second image of the scene. The system also includes a processor operatively coupled to the event camera and the shutter camera. The processor is configured to apply guided event filtering (GEF) on the first image and the second image. The processor is also configured to generate a third image based on filtering of the first image and the second image.
FILED Monday, April 12, 2021
APPL NO 17/227691
ART UNIT 2699 — Search and Capture Special Detail
CURRENT CPC
Image Data Processing or Generation, in General
G06T 1/0007 (20130101)
G06T 5/002 (20130101)
G06T 2207/10141 (20130101)
G06T 2207/20182 (20130101)

Pictorial Communication, e.g Television
H04N 5/2251 (20130101)
H04N 5/2258 (20130101) Original (OR) Class
H04N 5/23229 (20130101)
H04N 5/23254 (20130101)
H04N 5/23267 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11298561 Millenbaugh
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Bureau of Medicine and Surgery (BUMED)
Naval Medical Research Center (NMRC)
Naval Medical Research Unit San Antonio (NAMRU-SA)
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
Oak Ridge Institute for Science and Education (ORISE)
APPLICANT(S) The United States of America Represented by the Secretary of Navy (Silver Spring, Maryland)
ASSIGNEE(S) The United States of America As Represented by the Secretary of the Navy (Arlinton, Virginia)
INVENTOR(S) Nancy Millenbaugh (San Antonio, Texas)
ABSTRACT This application describes a method of using gold nanoparticle (GNP)-targeted pulsed laser technology to enhance antibiotic efficacy against multidrug resistant biofilms. The application also teaches a method for treating topic wound infection using GNP-targeted laser therapy combined with antibiotics treatments.
FILED Sunday, May 05, 2019
APPL NO 16/403564
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 41/0052 (20130101)
A61K 45/06 (20130101)
A61K 47/6835 (20170801)
A61K 47/6923 (20170801)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/062 (20130101) Original (OR) Class
A61N 5/0624 (20130101)
A61N 2005/067 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298653 Voskian et al.
FUNDED BY
Department of Energy (DOE)
Office of International Affairs (DOE-OIA)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Sahag Voskian (Cambridge, Massachusetts);  Trevor Alan Hatton (Sudbury, Massachusetts)
ABSTRACT The present disclosure generally relates to apparatuses, systems, and methods for separating a target species (e.g., CO2) from a gas mixture (e.g., gas stream) via an electrochemical process.
FILED Thursday, September 26, 2019
APPL NO 16/583826
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Separation
B01D 53/326 (20130101) Original (OR) Class
B01D 2257/504 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298679 Murph et al.
FUNDED BY
Department of Energy (DOE)
Office of Environmental Management (DOE-EM)
Savannah River National Laboratory (SRNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Savannah River Nuclear Solutions, LLC (SRNS) at Aiken, SC
APPLICANT(S) SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (Aiken, South Carolina)
ASSIGNEE(S) Savannah River Nuclear Solutions, LLC (Aiken, South Carolina)
INVENTOR(S) Simona H. Murph (North Augusta, South Carolina);  Kaitlin J. Lawrence (Aiken, South Carolina);  Henry T. Sessions (Aiken, South Carolina);  Michael A. Brown (Aiken, South Carolina)
ABSTRACT Multi-functional materials for use in reversible, high-capacity hydrogen separation and/or storage are described. Also described are systems incorporating the materials. The multi-functional materials combine a hydrogen-absorbing material with a high-efficiency and a non-contact energy-absorbing material in a composite nanoparticle. The non-contact energy-absorbing material include magnetic and/or plasmonic materials. The magnetic or plasmonic materials of the composite nanoparticles can provide localized heating to promote release of hydrogen from the hydrogen storage component of the composite nanoparticles.
FILED Wednesday, October 23, 2019
APPL NO 16/660853
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/0211 (20130101)
B01J 20/0214 (20130101)
B01J 20/0229 (20130101)
B01J 20/0233 (20130101)
B01J 20/0244 (20130101)
B01J 20/28007 (20130101) Original (OR) Class
B01J 20/28009 (20130101)
B01J 2220/42 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 3/0026 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298691 Liu et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Di-Jia Liu (Elmhurst, Illinois);  Hao Wang (Darien, Illinois)
ABSTRACT Prussian blue analog derived catalysts having a composition of highly porous transition metal (“TM”) oxides with nano particle size. Such OER catalysts are synthesized from the PBA, containing cobalt, iron, nickel, copper, manganese, zinc, magnesium etc., as secondary building units (“SBUs”) coordinated by hexacyano-based ligands. Furthermore, the PBA-derived catalysts may also integrated into a highly graphitized carbon network to further improve the conductivity, mass transport and durability against oxidative corrosion.
FILED Tuesday, February 19, 2019
APPL NO 16/279383
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 27/26 (20130101) Original (OR) Class
B01J 35/1014 (20130101)
B01J 35/1019 (20130101)
B01J 37/08 (20130101)
B01J 37/0036 (20130101)
B01J 2523/17 (20130101)
B01J 2523/27 (20130101)
B01J 2523/37 (20130101)
B01J 2523/39 (20130101)
B01J 2523/72 (20130101)
B01J 2523/842 (20130101)
B01J 2523/845 (20130101)
B01J 2523/847 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298754 Briggs
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Timothy Briggs (Brentwood, California)
ABSTRACT An apparatus and method for preparing Double Cantilever Beam (DCB) specimens are disclosed as an apparatus and method for conducting Mode I fracture resistance testing using the DCB specimens. In a first embodiment, a drill jig is used to locate the DCB specimen and guide a drilling process during creation of at least one through-hole in the DCB specimen. The drilling process may employ a traditional drill and drill bit, a laser drill, or a water jet. In another embodiment, a set of rotating pin blocks, each with a full-round or a half-round specimen pin at one end and a hanger full-round pin at the other end, engage the DCB specimen and facilitate the internal application of a fracturing load to the DCB specimen for the Mode I fracture resistance test. The present invention may significantly reduce the time and materials needed to prepare and test a DCB specimen.
FILED Wednesday, May 20, 2020
APPL NO 16/878731
ART UNIT 2866 — Printing/Measuring and Testing
CURRENT CPC
Turning; Boring
B23B 47/288 (20130101) Original (OR) Class

Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 5/0033 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 3/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299519 Ruegg
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Thomas L. Ruegg (Berkeley, California)
ABSTRACT The present invention provides for a system comprising (a) a first nucleic acid comprising a nucleotide sequence encoding a nucleotide sequence of interest operatively linked to a promoter comprising a repressor polypeptide binding site, and (b) a second nucleic acid comprising a nucleotide sequence encoding a repressor polypeptide having at least 70% amino acid identity with EilR, SmvR, KmrR, RcdA, or QacR; wherein expression of the nucleotide sequence of interest from the promoter is induced by the presence of a hydrophobic inducer, such as a hydrophobic cation inducer, such as a triarylmethane, acridine, phenazine, phenothiazine, or xanthene.
FILED Thursday, March 26, 2020
APPL NO 16/831649
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/245 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/63 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299523 Bush et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Colorado State University Research Foundation (Fort Collins, Colorado)
ASSIGNEE(S) Colorado State University Research Foundation (Fort Collins, Colorado)
INVENTOR(S) Daniel R. Bush (Fort Collins, Colorado);  Amanda K. Broz (Fort Collins, Colorado);  Bettina E. Broeckling (Fort Collins, Colorado);  Michael M. Friedman (Fort Collins, Colorado)
ABSTRACT The invention provides methods for improving plant yield, biomass accumulation and stress tolerance. A novel AP2-like transcription factor MPG1, which when modulated impacts grain yield, biomass and abiotic and biotic stress tolerance when compared to non-modulated plants. The invention further provides methods using recombinant expression cassettes, host cells, transgenic plants and breeding methods using the same.
FILED Thursday, July 06, 2017
APPL NO 16/315258
ART UNIT 1663 — Plants
CURRENT CPC
Peptides
C07K 14/415 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/827 (20130101)
C12N 15/8223 (20130101)
C12N 15/8271 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299816 Rose et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Klint A. Rose (Alviso, California);  Joshua D. Kuntz (Livermore, California);  Marcus A. Worsley (Hayward, California)
ABSTRACT A product according to one embodiment includes a first layer having a first composition, a first microstructure, and a first density; and a second layer above the first layer, the second layer having: a second composition, a second microstructure, and/or a second density. A gradient in composition, microstructure, and/or density exists between the first layer and the second layer, and either or both of the first layer and the second layer comprise non-spherical particles aligned along a longitudinal axis thereof.
FILED Wednesday, November 13, 2019
APPL NO 16/683101
ART UNIT 1784 — Miscellaneous Articles, Stock Material
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 15/00 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 37/001 (20130101)
C04B 37/025 (20130101)
C04B 2235/775 (20130101)
C04B 2235/787 (20130101)
C04B 2235/5296 (20130101)
C04B 2235/9653 (20130101)
C04B 2237/32 (20130101)
C04B 2237/083 (20130101)
C04B 2237/402 (20130101)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 13/02 (20130101) Original (OR) Class
C25D 13/12 (20130101)
C25D 13/20 (20130101)
C25D 13/22 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/252 (20150115)
Y10T 428/12458 (20150115)
Y10T 428/24802 (20150115)
Y10T 428/24992 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300093 Obermeyer et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Henry K. Obermeyer (Wellington, Colorado)
ASSIGNEE(S) Henry Obermeyer (Wellington, Colorado)
INVENTOR(S) Henry K. Obermeyer (Wellington, Colorado);  Claudiu M. Iavornic (Fort Collins, Colorado);  Grant Quinn Baker (Arlington, Virginia)
ABSTRACT The present invention is a reversible pump-turbine installation positioned in a vertical borehole instead of in a conventional underground powerhouse or deep concrete powerhouse. The required plant cavitation coefficient may be achieved by simply boring a vertical borehole to the required depth rather than routing the water flow to and from a deeply buried powerhouse. A pneumatically controlled pressure relief valve may be incorporated into this invention.
FILED Monday, April 30, 2018
APPL NO 16/322185
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Hydraulic Engineering
E02B 9/00 (20130101)
E02B 9/06 (20130101)

Machines or Engines for Liquids
F03B 3/103 (20130101)
F03B 13/06 (20130101) Original (OR) Class
F03B 13/10 (20130101)

Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G
F05B 2220/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300236 Liszkai
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
APPLICANT(S) NuScale Power, LLC (Corvallis, Oregon)
ASSIGNEE(S) NuScale Power, LLC (Corvallis, Oregon)
INVENTOR(S) Tamas Liszkai (Corvallis, Oregon)
ABSTRACT In an example, a raised face flange assembly, comprises an upper flange to couple to a lower flange using one or more bolts: wherein the upper flange or the lower flange comprises: a bolting face defining one or more openings for the one or more bolts, respectively; a pair of raised faces including a first raised face and a second raised face to make contact with a mating surface of the other of the upper flange or the lower flange; wherein a distance between an area of the second raised face and a plane corresponding to the bolting face is greater than a distance between an area of the first raised face and the plane to distribute contact force with a mating surface over the area of the second raised face to maintain a seal.
FILED Friday, December 14, 2018
APPL NO 16/221088
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General
F16L 23/16 (20130101)
F16L 23/032 (20130101) Original (OR) Class

Nuclear Reactors
G21C 13/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300555 Cooks et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Robert Graham Cooks (West Lafayette, Indiana);  Fred Paul Mark Jjunju (West Lafayette, Indiana);  Anyin Li (West Lafayette, Indiana);  Iman S. Roqan (Thuwal, Saudi Arabia)
ABSTRACT The invention generally relates to methods of analyzing crude oil. In certain embodiments, methods of the invention involve obtaining a crude oil sample, and subjecting the crude oil sample to mass spectrometry analysis. In certain embodiments, the method is performed without any sample pre-purification steps.
FILED Friday, January 17, 2020
APPL NO 16/746120
ART UNIT 2881 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 30/724 (20130101)
G01N 30/7266 (20130101)
G01N 33/2823 (20130101) Original (OR) Class

Electric Discharge Tubes or Discharge Lamps
H01J 49/04 (20130101)
H01J 49/10 (20130101)
H01J 49/16 (20130101)
H01J 49/0031 (20130101)
H01J 49/164 (20130101)
H01J 49/165 (20130101)
H01J 49/168 (20130101)
H01J 49/0445 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300562 Sussman et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Michael R. Sussman (Cross Plains, Wisconsin);  J. Leon Shohet (Madison, Wisconsin);  Faraz A. Choudhury (Madison, Wisconsin);  Joshua M. Blatz (Monona, Wisconsin);  Benjamin B. Minkoff (Madison, Wisconsin);  Daniel I. Benjamin (Madison, Wisconsin)
ABSTRACT This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.
FILED Thursday, January 16, 2020
APPL NO 16/745182
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/088 (20130101)
B01J 2219/0809 (20130101)
B01J 2219/0894 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6876 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/28 (20130101)
G01N 33/50 (20130101) Original (OR) Class
G01N 33/487 (20130101)
G01N 33/6848 (20130101)
G01N 2333/765 (20130101)
G01N 2333/90216 (20130101)
G01N 2333/91215 (20130101)
G01N 2440/00 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 49/0031 (20130101)

Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 1/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300572 Coleman et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S) Matthew A. Coleman (Oakland, California);  Paul D. Hoeprich (Pleasanton, California);  Brent W. Segelke (San Ramon, California)
ABSTRACT Provided herein are methods and systems for the production of a nanolipoprotein particle (NLP) that includes a scaffold protein a membrane forming lipid and optionally a target protein. At least one of the scaffold protein and target protein can be provided through an IVT system. The membrane forming lipid, scaffold protein and optionally the target protein can be assembled for a time and under conditions that allow obtaining high yield NLPs, NPLs with an increased solubility, an NLP of a controlled size, and/or an NLP having a size predetermined to include a pre-selected target protein.
FILED Friday, October 12, 2018
APPL NO 16/159189
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 14/705 (20130101)
C07K 14/775 (20130101)
C07K 17/02 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 21/02 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/582 (20130101)
G01N 33/587 (20130101) Original (OR) Class
G01N 33/54346 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300707 Hamann et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Hendrik F. Hamann (Yorktown Heights, New York);  Ildar Khabibrakhmanov (Syosset, New York);  Younghun Kim (White Plains, New York);  Siyuan Lu (Yorktown Heights, New York)
ABSTRACT Methods and systems for predicting irradiance include learning a classification model using unsupervised learning based on historical irradiance data. The classification model is updated using supervised learning based on an association between known cloudiness states and historical weather data. A cloudiness state is predicted based on forecasted weather data. An irradiance is predicted using a regression model associated with the cloudiness state.
FILED Tuesday, August 02, 2016
APPL NO 15/226445
ART UNIT 2126 — AI & Simulation/Modeling
CURRENT CPC
Meteorology
G01W 1/10 (20130101) Original (OR) Class
G01W 1/12 (20130101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300978 Samaras
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Constantinos Samaras (Pittsburgh, Pennsylvania)
ABSTRACT A method, system, and computer program product is provided for transporting an unmanned vehicle to a destination location. The method includes determining a ground vehicle from a plurality of ground vehicles based on a location of the ground vehicle, the destination location, and a location of the unmanned vehicle, controlling the unmanned vehicle to the location of the ground vehicle, controlling at least one attachment mechanism to attach the unmanned vehicle to the ground vehicle, in response to the ground vehicle traveling to a second location, controlling the at least one attachment mechanism to detach the unmanned vehicle from the ground vehicle, and controlling the unmanned vehicle to the destination location.
FILED Tuesday, July 09, 2019
APPL NO 16/505995
ART UNIT 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Vehicles Adapted for Load Transportation or to Transport, to Carry, or to Comprise Special Loads or Objects
B60P 3/11 (20130101)

Aeroplanes; Helicopters
B64C 39/024 (20130101)
B64C 2201/027 (20130101)
B64C 2201/208 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 1/12 (20130101) Original (OR) Class
G05D 1/021 (20130101)
G05D 1/101 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 20/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11301165 Gooding et al.
FUNDED BY
Department of Energy (DOE)
Collaboration of Oak Ridge, Argonne, and Livermore (CORAL)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Thomas Gooding (Rochester, Minnesota);  Pierre Lemarinier (Leixlip, Ireland);  Bryan S. Rosenburg (Cortlandt Manor, New York)
ABSTRACT A data management system and method for accelerating shared file checkpointing. Written application data is aggregated in an application data file created in a local burst buffer memory at a compute node, and an associated data mapping built index to maintain information related to the offsets into a shared file at which segments of the application data is to be stored in a parallel file system, and where in the buffer those segments are located. The node asynchronously transfers a data file containing the application data and the associated data mapping index to a file server for shared file storage. The data management system and method further accelerates shared file checkpointing in which a shared file, together with a map file that specifies how the shared file is to be distributed, is asynchronously transferred to local burst buffer memories at the nodes to accelerate reading of the shared file.
FILED Thursday, April 26, 2018
APPL NO 15/963700
ART UNIT 2159 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 3/067 (20130101)
G06F 3/0611 (20130101)
G06F 3/0643 (20130101)
G06F 3/0644 (20130101)
G06F 3/0656 (20130101)
G06F 3/0659 (20130101) Original (OR) Class
G06F 16/1858 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11302472 Wang et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S) Jian-Ping Wang (Shoreview, Minnesota);  Yanfeng Jiang (Minneapolis, Minnesota)
ABSTRACT Techniques are disclosed concerning applied magnetic field synthesis and processing of iron nitride magnetic materials. Some methods concern casting a material including iron in the presence of an applied magnetic field to form a workpiece including at least one ironbased phase domain including uniaxial magnetic anisotropy, wherein the applied magnetic field has a strength of at least about 0.01 Tesla (T). Also disclosed are workpieces made by such methods, apparatus for making such workpieces and bulk materials made by such methods.
FILED Wednesday, July 22, 2015
APPL NO 15/546407
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Casting of Metals; Casting of Other Substances by the Same Processes or Devices
B22D 27/02 (20130101)

Alloys
C22C 38/001 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/06 (20130101)
H01F 1/08 (20130101)
H01F 1/047 (20130101)
H01F 41/0266 (20130101)
H01F 41/0273 (20130101) Original (OR) Class

Dynamo-electric Machines
H02K 1/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11302531 Norman et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  Colorado School of Mines (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  Colorado School of Mines (Golden, Colorado)
INVENTOR(S) Andrew Gordon Norman (Evergreen, Colorado);  Celeste Louise Melamed (Golden, Colorado);  Eric Steven Toberer (Golden, Colorado);  William Edwin McMahon (Denver, Colorado)
ABSTRACT Disclosed herein are methods for exfoliation of single crystals allowing for growth of high crystalline quality on the exfoliated surfaces for III-V photovoltaics. Also disclosed herein are methods for growing GaAs (111) on layered-2D Bi2Se3 (0001) substrates in an MOCVD reactor.
FILED Wednesday, August 26, 2020
APPL NO 17/003194
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 25/186 (20130101)
C30B 29/42 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0262 (20130101)
H01L 21/02477 (20130101)
H01L 21/02546 (20130101)
H01L 21/02598 (20130101)
H01L 21/02658 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11302868 Zhu et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Kai Zhu (Littleton, Colorado);  Fei Zhang (Lakewood, Colorado);  Joseph Jonathan Berry (Boulder, Colorado)
ABSTRACT The present disclosure relates to a method that includes applying a first perovskite precursor solution to a substrate to form a first liquid film of the first perovskite precursor solution on the substrate; from the first liquid film, forming a first intermediate solid perovskite layer on the substrate; repeating at least once, both the applying and the forming, resulting in the creation of at least one additional intermediate solid perovskite layer; and treating a last intermediate solid perovskite layer, resulting from the at least one additional applying and the at least one additional forming, to create a final solid perovskite layer.
FILED Wednesday, February 05, 2020
APPL NO 16/782891
ART UNIT 2897 — Semiconductors/Memory
CURRENT CPC
Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/34 (20130101)

Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 9/2059 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0002 (20130101)
H01L 51/0003 (20130101) Original (OR) Class
H01L 51/0026 (20130101)
H01L 51/42 (20130101)
H01L 51/4246 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/549 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11302881 Forrest et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Stephen R. Forrest (Ann Arbor, Michigan);  Noel C. Giebink (Downers Grove, Illinois)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Stephen R. Forrest (Ann Arbor, Michigan);  Noel C. Giebink (Downers Grove, Illinois)
ABSTRACT The present disclosure generally relates to organic photosensitive optoelectronic devices and polaron pair recombination dynamics to impact efficiency and open circuit voltages of organic solar cells. The present disclosure also relates, in part, to methods of making organic photosensitive optoelectronic devices comprising the same.
FILED Tuesday, May 03, 2011
APPL NO 13/099716
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/001 (20130101)
H01L 51/0046 (20130101)
H01L 51/0047 (20130101)
H01L 51/0054 (20130101)
H01L 51/0055 (20130101)
H01L 51/0078 (20130101)
H01L 51/0091 (20130101)
H01L 51/4253 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/549 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11302917 Yadav et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (New York, New York)
ASSIGNEE(S) Research Foundation of City University of New York (, None)
INVENTOR(S) Gautam G. Yadav (New York, New York);  Xia Wei (New York, New York);  Michael Nyce (New York, New York);  Sanjoy Banerjee (New York, New York)
ABSTRACT A method of forming a layered manganese dioxide for use in a cathode of a battery comprises disposing a cathode into a housing of an electrochemical cell, disposing an anode into the housing, disposing a polymeric separator between the anode and the cathode such that the anode and the cathode are electrically separated, adding an alkaline electrolyte to the housing, cycling the electrochemical cell into the 2nd electron capacity of the manganese dioxide, and forming a layered manganese dioxide having a layered manganese dioxide structure with the one or more additives incorporated into the layered manganese dioxide structure. The cathode comprising a cathode material comprising: a manganese dioxide compound, one or more additives selected from the group consisting of bismuth, copper, tin, lead, silver, cobalt, nickel, magnesium, aluminum, potassium, lithium, calcium, gold, antimony, iron, zinc, and combinations thereof, and a conductive carbon.
FILED Friday, July 27, 2018
APPL NO 16/634054
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/50 (20130101) Original (OR) Class
H01M 4/0438 (20130101)
H01M 4/625 (20130101)
H01M 4/626 (20130101)
H01M 6/04 (20130101)
H01M 10/28 (20130101)
H01M 2004/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11302948 Benicewicz et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina)
ASSIGNEE(S) University of South Carolina (Columbia, South Carolina)
INVENTOR(S) Brian C. Benicewicz (Columbia, South Carolina);  Laura Murdock (Columbia, South Carolina);  Lihui Wang (West Columbia, South Carolina);  Fei Huang (West Columbia, South Carolina);  Andrew Pingitore (Columbia, South Carolina)
ABSTRACT Disclosed are redox flow battery membranes, redox flow batteries incorporating the membranes, and methods of forming the membranes. The membranes include a polybenzimidazole gel membrane that is capable of incorporating a high liquid content without loss of structure that is formed according to a process that includes in situ hydrolysis of a polyphosphoric acid solvent. The membranes are imbibed with a redox flow battery supporting electrolyte such as sulfuric acid and can operate at very high ionic conductivities of about 100 mS/cm or greater. Redox flow batteries incorporating the PBI-based membranes can operate at high current densities of about 100 mA/cm2 or greater.
FILED Friday, September 13, 2019
APPL NO 16/570290
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/92 (20130101)
H01M 4/8605 (20130101)
H01M 4/8828 (20130101)
H01M 8/1027 (20130101) Original (OR) Class
H01M 8/1032 (20130101)
H01M 8/1044 (20130101)
H01M 8/1048 (20130101)
H01M 8/1067 (20130101)
H01M 8/1081 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11303005 Roberts
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Nuclear Physics Program (DOE-NP)
APPLICANT(S) Brock Franklin Roberts (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S) Brock Franklin Roberts (Albuquerque, New Mexico)
ABSTRACT The harmonic combiner and divider efficiently combines multiple harmonic signals onto a common transmission line. Combined harmonic signals can be used to generate fast, high-fidelity arbitrary waveforms by superimposing the harmonics described in their Fourier series. Fast arbitrary waveforms have applications in communications, radar, and can be used for manipulating and controlling charged particle beams. The harmonic combiner and divider also efficiently divides fast arbitrary waveforms into their constituent harmonics and provides an efficient mechanism for waveform analysis and for multi-channel communications.
FILED Thursday, January 16, 2020
APPL NO 16/873026
ART UNIT 2843 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 5/19 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11297828 Chakraborty
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Nilay Chakraborty (Troy, Michigan)
ABSTRACT Methods and devices for lyo-processing biological materials are provided. The methods include submerging the biological molecules or cells in a buffer solution comprising trehalose, withdrawing the biological molecules or cells from the buffer solution in an environment that does not include oxygen to generate lyo-stabilized biological molecules or cells, and storing the lyo-stabilized biological molecules or cells. The devices include a motor that lowers a horizontal member having a clamp for receiving a substrate toward a solvent reservoir and raises the horizontal member having the clamp up and away from the solvent reservoir.
FILED Tuesday, March 14, 2017
APPL NO 16/085379
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 1/0221 (20130101) Original (OR) Class
A01N 1/0231 (20130101)
A01N 1/0284 (20130101)
A01N 1/0289 (20130101)

Drying Solid Materials or Objects by Removing Liquid Therefrom
F26B 5/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298423 Jeffries et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Nursing Research (NINR)
National Science Foundation (NSF)
Directorate of Technology
Translational Impacts (TI)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Eric M. Jeffries (West New York, New Jersey);  Noah R. Johnson (Pittsburgh, Pennsylvania);  Daniel Long (Pittsburgh, Pennsylvania);  Yadong Wang (Bradford Woods, Pennsylvania)
ABSTRACT Compositions are provided herein comprising a coacervate of a polycationic polymer, a polyanionic polymer, and platelet-rich plasma and/or serum, or a fraction or concentrate thereof. The composition is useful in wound healing. Compositions also are provided that comprise a hydrogel comprising TIMP-3; and a complex of a polycationic polymer, a polyanionic polymer, FGF-2 and SDF-1α embedded in the hydrogel, which is useful in treating a myocardial infarction.
FILED Friday, March 03, 2017
APPL NO 16/080812
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/0019 (20130101)
A61K 35/16 (20130101)
A61K 35/19 (20130101)
A61K 38/18 (20130101)
A61K 38/177 (20130101)
A61K 38/195 (20130101)
A61K 38/1825 (20130101)
A61K 47/34 (20130101)
A61K 47/36 (20130101) Original (OR) Class
A61K 47/42 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 15/40 (20130101)
A61L 15/44 (20130101)
A61L 15/225 (20130101)
A61L 15/225 (20130101)
A61L 27/18 (20130101)
A61L 27/20 (20130101)
A61L 27/26 (20130101)
A61L 27/26 (20130101)
A61L 27/52 (20130101)
A61L 27/54 (20130101)
A61L 27/56 (20130101)
A61L 27/225 (20130101)
A61L 27/3616 (20130101)
A61L 31/16 (20130101)
A61L 31/041 (20130101)
A61L 31/042 (20130101)
A61L 31/046 (20130101)
A61L 31/145 (20130101)
A61L 2300/25 (20130101)
A61L 2300/252 (20130101)
A61L 2300/414 (20130101)
A61L 2300/418 (20130101)
A61L 2400/04 (20130101)
A61L 2430/20 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/10 (20180101)

Compositions of Macromolecular Compounds
C08L 5/10 (20130101)
C08L 5/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298821 Sun et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) University of South Florida (Tampa, Florida)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Yu Sun (Tampa, Florida);  Yongqiang Huang (Tampa, Florida)
ABSTRACT System and methods for generating a trajectory of a dynamical system are described herein. An example method includes modelling a policy from demonstration data. The method also includes generating a first set of action particles by sampling from the policy, where each of the action particles in the first set includes a respective system action, predicting a respective outcome of the dynamical system in response to each of the action particles in the first set, and weighting each of the action particles in the first set according to a respective probability of achieving a desired outcome. The method further includes generating a second set of action particles by sampling from the weighted action particles, where each of the action particles in the second set includes a respective system action, and selecting a next system action in the trajectory of the dynamical system from the action particles in the second set.
FILED Wednesday, April 01, 2020
APPL NO 16/837548
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/163 (20130101) Original (OR) Class
B25J 9/1661 (20130101)
B25J 9/1664 (20130101)

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/42 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298825 Chu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Diligent Robotics, Inc. (Austin, Texas)
ASSIGNEE(S) Diligent Robotics, Inc. (Austin, Texas)
INVENTOR(S) Vivian Yaw-Wen Chu (Austin, Texas);  Shuai Li (Sammamish, Washington);  Forrest Green (Austin, Texas);  Peter Worsnop (Bethesda, Maryland);  Andrea Lockerd Thomaz (Austin, Texas)
ABSTRACT Systems, apparatus, and methods are described for robotic learning and execution of skills. A robotic apparatus can include a memory, a processor, sensors, and one or more movable components (e.g., a manipulating element and/or a transport element). The processor can be operatively coupled to the memory, the movable elements, and the sensors, and configured to obtain information of an environment, including one or more objects located within the environment. In some embodiments, the processor can be configured to learn skills through demonstration, exploration, user inputs, etc. In some embodiments, the processor can be configured to execute skills and/or arbitrate between different behaviors and/or actions. In some embodiments, the processor can be configured to learn an environmental constraint. In some embodiments, the processor can be configured to learn using a general model of a skill.
FILED Monday, October 18, 2021
APPL NO 17/504130
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 5/00 (20130101)
B25J 9/06 (20130101)
B25J 9/0081 (20130101)
B25J 9/163 (20130101)
B25J 9/1661 (20130101) Original (OR) Class
B25J 9/1694 (20130101)
B25J 11/0005 (20130101)
B25J 15/00 (20130101)
B25J 19/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299399 Fulton et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) University of Oregon (Eugene, Oregon);  Oregon State University (Corvallis, Oregon)
ASSIGNEE(S) University of Oregon (Eugene, Oregon);  Oregon State University (Corvallis, Oregon)
INVENTOR(S) Brantly Fulton (Eugene, Oregon);  Milton N. Jackson, Jr. (Eugene, Oregon);  Darren W. Johnson (Eugene, Oregon);  Shannon W. Boettcher (Eugene, Oregon);  Cory K. Perkins (Corvallis, Oregon);  Douglas A. Keszler (Eugene, Oregon);  James E. Hutchison (Eugene, Oregon)
ABSTRACT A method comprising reacting an aluminum mineral polymorph or a gallium mineral polymorph with an acid at an aluminum metal to acid molar ratio or gallium metal to acid molar ratio sufficient to produce M13 nanoscale clusters, M nano-agglomerates, or a M13 slurry, wherein M is Al or Ga.
FILED Tuesday, December 17, 2019
APPL NO 16/717853
ART UNIT 1759 — Printing/Measuring and Testing
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals
C01F 7/20 (20130101)
C01F 7/24 (20130101) Original (OR) Class

Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 15/00 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/70 (20130101)
C01P 2002/82 (20130101)
C01P 2004/50 (20130101)
C01P 2004/64 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299509 Cheng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Jianjun Cheng (Champaign, Illinois);  Kaimin Cai (Urbana, Illinois);  Jin Yu (Urbana, Illinois)
ABSTRACT Disclosed are compounds for the selective labeling of cell-surface sugars in cancer cells. The compounds are activatable by triggers specific to cancer cells, and, when metabolized, label a cancer cell surface sugar with an azide chemical group. Facilitated by a click chemistry reaction, combination of the cell surface-expressed azide with a alkynyl-drug conjugate enables efficient targeted drug delivery to cancer cells with reduced toxicity. Also disclosed are compounds for delivering a drug to an azide-bearing cancer cell, and methods of treating cancer using the compounds.
FILED Monday, February 12, 2018
APPL NO 16/485090
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/704 (20130101)
A61K 31/5365 (20130101)
A61K 47/549 (20170801)
A61K 47/555 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 15/18 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299776 Ellington et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Aeronautics and Space Administration (NASA)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Andrew Ellington (Austin, Texas);  Cheulhee Jung (Austin, Texas);  Sheng Cai (Zhejiang, China PRC);  Sanchita Bhadra (Austin, Texas);  John N. Milligan (Austin, Texas);  Daniel Garry (Austin, Texas);  Raghav Shroff (Austin, Texas)
ABSTRACT Disclosed are compositions and methods for nucleic acid amplification and detection. Specifically, disclosed herein are compositions and methods that allow for amplification of nucleic acids at a wide variety of temperatures. This includes a polymerase which is thermostable at high temperatures, and a method of amplification that can be conducted at relatively low temperatures.
FILED Thursday, May 10, 2018
APPL NO 16/612020
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1252 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/6853 (20130101) Original (OR) Class
C12Q 2521/101 (20130101)
C12Q 2525/301 (20130101)
C12Q 2527/101 (20130101)
C12Q 2531/101 (20130101)
C12Q 2537/1373 (20130101)
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299780 Green
FUNDED BY
National Science Foundation (NSF)
Directorate for Social, Behavioral and Economic Sciences (SBE)
SBE Office of Multidisciplinary Activities (SMA)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Richard E. Green (Santa Cruz, California)
ABSTRACT Provided are methods of producing nucleic acid libraries. In certain aspects, the methods include combining target nucleic acids (e.g., 5′ phosphorylated nucleic acids) and an oligonucleotide pool. Oligonucleotides of the oligonucleotide pool may include complementarity regions of varying length and nucleotide sequence, and a complementarity region identification sequence. In such aspects, the combining is under conditions in which oligonucleotides of the oligonucleotide pool hybridize to nucleic acids of the target nucleic acids (e.g., 5′ phosphorylated nucleic acids) having overhang regions that are complementary in sequence and have corresponding lengths with respect to the complementarity regions of the oligonucleotides. Compositions and kits that find use, e.g., in practicing the methods of the present disclosure are also provided.
FILED Thursday, July 13, 2017
APPL NO 16/316268
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)
C12Q 1/6869 (20130101) Original (OR) Class
C12Q 2521/501 (20130101)
C12Q 2525/179 (20130101)
C12Q 2525/191 (20130101)
C12Q 2525/204 (20130101)
C12Q 2533/107 (20130101)
C12Q 2563/179 (20130101)
C12Q 2565/631 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300176 Bonessio
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology
Translational Impacts (TI)
APPLICANT(S) METAseismic, Inc. (Irvine, California)
ASSIGNEE(S) METAseismic, Inc. (Irvine, California)
INVENTOR(S) Noemi Bonessio (Irvine, California)
ABSTRACT A vibration absorbing apparatus is disclosed for functioning as a practical mechanical metamaterial for anisotropic vibration control. In at least one embodiment, the apparatus provides a plurality of rail units positioned in a side-by-side arrangement so as to form at least one rail unit layer. Each rail unit provides a first plate and an opposing second plate slidably engaged with the first plate. The first plate provides at least one substantially linear slide rail extending therefrom. The second plate provides a corresponding at least one substantially linear slot sized for slidably receiving the corresponding at least one slide rail. At least one resilient connector extends between the first and second plates so as to maintain slidable engagement between the first and second plates. Additionally, the at least one slot of each rail unit of the at least one rail unit layer is oriented in substantially the same direction.
FILED Tuesday, November 03, 2020
APPL NO 17/087875
ART UNIT 3657 — Material and Article Handling
CURRENT CPC
Springs; Shock-absorbers; Means for Damping Vibration
F16F 15/04 (20130101) Original (OR) Class
F16F 15/021 (20130101)
F16F 2230/36 (20130101)
F16F 2230/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300502 Duan et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Lingze Duan (Madison, Alabama);  Lin Yang (Chapel Hill, North Carolina)
ASSIGNEE(S) Board of Trustees of the University of Alabama, for and on behalf of the University of Alabama in Huntsville (Huntsville, Alabama)
INVENTOR(S) Lingze Duan (Madison, Alabama);  Lin Yang (Chapel Hill, North Carolina)
ABSTRACT A time-wavelength optical sampling system may be configured to determine a substance's composition based on variations in optical pulses caused by the substance's absorption of wavelengths of the pulse. A dispersion medium may disperse pulses to form stretched signal pulses that are incident on a substance under test. Optical gating is used to overlap each signal pulse with a portion of a reference pulse to generate a cross-correlation signal corresponding to a portion of the signal pulse, which may be detected by a slow detection speed detector. A controller controls delay introduced to the reference pulses so that different wavelength ranges are sampled for various signal pulses, thereby enabling the entire wavelength range for the signal pulses to be sampled over time without requiring an expensive high-speed optical detector. By analyzing absorption across the entire wavelength range as indicated by cross-correlation signals, the composition of the substance can be identified.
FILED Friday, May 17, 2019
APPL NO 16/415562
ART UNIT 2878 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/27 (20130101)
G01N 21/255 (20130101) Original (OR) Class
G01N 2201/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300515 Lew et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Matthew Lew (St. Louis, Missouri);  Arye Nehorai (St. Louis, Missouri);  Hesamaldin Mazidisharfabadi (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Matthew Lew (St. Louis, Missouri);  Arye Nehorai (St. Louis, Missouri);  Hesamaldin Mazidisharfabadi (St. Louis, Missouri)
ABSTRACT Systems and methods assessing the accuracy of at least one localization from a single molecule localization microscopy (SMLM) dataset containing a plurality of localizations are described. The systems and methods calculate a Wasserstein-induced flux (WIF) value indicative of a confidence in the accuracy of a localization within the SMLM data set.
FILED Thursday, July 30, 2020
APPL NO 16/943937
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6458 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 7/73 (20170101)
G06T 2207/10056 (20130101)
G06T 2207/30168 (20130101)
G06T 2207/30241 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300562 Sussman et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Michael R. Sussman (Cross Plains, Wisconsin);  J. Leon Shohet (Madison, Wisconsin);  Faraz A. Choudhury (Madison, Wisconsin);  Joshua M. Blatz (Monona, Wisconsin);  Benjamin B. Minkoff (Madison, Wisconsin);  Daniel I. Benjamin (Madison, Wisconsin)
ABSTRACT This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.
FILED Thursday, January 16, 2020
APPL NO 16/745182
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/088 (20130101)
B01J 2219/0809 (20130101)
B01J 2219/0894 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6876 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/28 (20130101)
G01N 33/50 (20130101) Original (OR) Class
G01N 33/487 (20130101)
G01N 33/6848 (20130101)
G01N 2333/765 (20130101)
G01N 2333/90216 (20130101)
G01N 2333/91215 (20130101)
G01N 2440/00 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 49/0031 (20130101)

Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 1/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300653 Hubbert
FUNDED BY
Department of Commerce (DOC)
National Oceanic and Atmospheric Administration (NOAA)
National Science Foundation (NSF)
National Center for Atmospheric Research (NCAR)
Federally Funded Research and Development Center (FFRDC)
Operated by University Corporation for Atmospheric Research (UCAR) at Boulder, CO
APPLICANT(S) University Corporation for Atmospheric Research (Boulder, Colorado)
ASSIGNEE(S) University Corporation for Atmospheric Research (Boulder, Colorado)
INVENTOR(S) John Clark Hubbert (Fort Collins, Colorado)
ABSTRACT A method and system for removing ground clutter data from time series radar data are provided. The method comprises receiving the time series radar data, applying a clutter filter to the time series radar data to generate a filtered time series radar data, applying a discrete Fourier transform to the filtered time series radar data to generate a filtered frequency domain data, determining a filter bias for one or more filter biased frequency domain frequencies of the filtered frequency domain data based on a frequency response of the clutter filter, and correcting the filtered frequency domain data by adding the filter bias to the filtered frequency domain data at the one or more filter biased frequency domain frequencies to generate a filtered and bias corrected frequency domain data.
FILED Thursday, July 11, 2019
APPL NO 16/508858
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/288 (20130101) Original (OR) Class
G01S 7/2883 (20210501)
G01S 7/2925 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300774 Dickensheets et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) MONTANA STATE UNIVERSITY (Bozeman, Montana);  MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S) MONTANA STATE UNIVERSITY (Bozeman, Montana);  MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York)
INVENTOR(S) David Dickensheets (Dozeman, Montana);  Milind Rajadhyaksha (New York, New York)
ABSTRACT Handheld devices and methods that integrate wide-field dermoscopy with reflectance confocal microscopy for non-invasive simultaneous capture of wide-field color images of the skin surface and images of the sub-surface cellular structure.
FILED Saturday, February 11, 2017
APPL NO 16/077352
ART UNIT 2872 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0068 (20130101)
A61B 5/0075 (20130101)
A61B 5/0077 (20130101)
A61B 5/444 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/02 (20130101)
G02B 21/06 (20130101)
G02B 21/0008 (20130101)
G02B 21/0028 (20130101)
G02B 21/0036 (20130101)
G02B 21/361 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300790 Cheng et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona);  BEIJING INSTITUTE OF TECHNOLOGY (Beijing, China PRC)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona);  BEIJING INSTITUTE OF TECHNOLOGY (Beijing, China PRC)
INVENTOR(S) Dewen Cheng (Beijing, China PRC);  Hong Hua (Tucson, Arizona);  Yongtian Wang (Beijing, China PRC)
ABSTRACT A see-through free-form head-mounted display including a wedge-shaped prism-lens having free-form surfaces and low F-number is provided.
FILED Thursday, August 15, 2019
APPL NO 16/541929
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 13/10 (20130101)
G02B 17/006 (20130101)
G02B 17/08 (20130101)
G02B 17/086 (20130101)
G02B 27/017 (20130101)
G02B 27/0172 (20130101) Original (OR) Class
G02B 2027/013 (20130101)
G02B 2027/0118 (20130101)

Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor
G03B 21/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300968 Pierson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Alyssa Pierson (Somerville, Massachusetts);  Wilko Schwarting (Cambridge, Massachusetts);  Sertac Karaman (Cambridge, Massachusetts);  Daniela L. Rus (Weston, Massachusetts)
ABSTRACT A method is disclosed for use in a planning agent, the method including: identifying a first agent in a vicinity of the planning agent; identifying a location of the first agent and a velocity of the first agent; calculating a set of occupancy costs for the first agent, each occupancy cost in the set of occupancy costs being associated with a different respective location in the vicinity of the planning agent, each occupancy cost in the set of occupancy costs being calculated at least in part based on a cost function that depends on the location of the first agent and the velocity of the first agent; and changing at least one of speed or direction of travel of the planning agent based on the set of occupancy costs.
FILED Friday, February 22, 2019
APPL NO 16/283158
ART UNIT 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Systems for Controlling or Regulating Non-electric Variables
G05D 1/0214 (20130101)
G05D 1/0223 (20130101) Original (OR) Class
G05D 2201/0213 (20130101)

Electric Digital Data Processing
G06F 16/29 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11301019 Lukas et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Christopher J. Lukas (Charlottesville, Virginia);  Benton H. Calhoun (Charlottesville, Virginia);  Farah B. Yahya (Charlottesville, Virginia)
ABSTRACT A system-on-a-chip (SoC) comprises a power supply circuit coupled to an energy harvesting transducer and configured to operate using energy from the energy harvesting transducer; a microcontroller coupled to a system bus of the SoC; an interface configured to communicate with the microcontroller via the system bus of the SoC, the interface configured to generate data upon occurrence of an event; and a computation accelerator configured to establish, based on an energy consumption level of the SoC, a data path between the interface and the computation accelerator that at least partially bypasses the system bus such that the data is transmitted to the computation accelerator via the data path.
FILED Monday, November 02, 2020
APPL NO 16/949535
ART UNIT 2186 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 1/26 (20130101)
G06F 1/30 (20130101) Original (OR) Class
G06F 1/3206 (20130101)
G06F 1/3215 (20130101)
G06F 9/4403 (20130101)
G06F 11/1451 (20130101)
G06F 11/1469 (20130101)
G06F 13/36 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11301243 Mayer et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) THE UNIVERSITY OF CHICAGO (Chicago, Illinois)
ASSIGNEE(S) THE UNIVERSITY OF CHICAGO (Chicago, Illinois)
INVENTOR(S) Mikaël Mayer (Chicago, Illinois);  Ravi Chugh (Chicago, Illinois)
ABSTRACT A method of facilitating bidirectional programming of a user may include receiving an original program source code and evaluating the original program source code in the forward direction to generate a program output. The evaluation may occur in a programming environment. The program output may be displayed, and an indication of the user corresponding to modifying the program output may be received. The modified program output may be evaluated to generate an updated program source code, wherein the updated program source code, when evaluated, may generate the modified program output. The modified program output may be displayed in a display device of the user. A computing system including a bidirectional programming environment may also be included.
FILED Friday, April 09, 2021
APPL NO 17/227227
ART UNIT 2193 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 8/34 (20130101)
G06F 8/71 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11302685 Wang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan)
ASSIGNEE(S) BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan)
INVENTOR(S) Chuan Wang (Haslett, Michigan);  Le Cai (Los Angeles, California)
ABSTRACT Printable and stretchable thin-film devices and fabrication techniques are provided for forming fully-printed, intrinsically stretchable thin-film transistors and integrated logic circuits using stretchable elastomer substrates such as polydimethylsiloxane (PDMS), semiconducting carbon nanotube network as channel, unsorted carbon nanotube network as source/drain/gate electrodes, and BaTiO3/PDMS composite as gate dielectric. Printable stretchable dielectric layer ink may be formed by mixing barium titanate nanoparticle (BaTiO3) with PDMS using 4-methyl-2-pentanone as solvent.
FILED Monday, November 19, 2018
APPL NO 16/195004
ART UNIT 2898 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/84 (20130101)
H01L 21/02109 (20130101)
H01L 21/02118 (20130101)
H01L 21/02126 (20130101)
H01L 21/02288 (20130101)
H01L 21/3105 (20130101)
H01L 23/5387 (20130101)
H01L 27/016 (20130101) Original (OR) Class
H01L 27/1214 (20130101)
H01L 29/517 (20130101)
H01L 29/4908 (20130101)
H01L 51/0048 (20130101)
H01L 51/055 (20130101)
H01L 51/0097 (20130101)
H01L 51/105 (20130101)
H01L 51/0537 (20130101)

Pulse Technique
H03K 19/21 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11303018 Yilmaz et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Mustafa Harun Yilmaz (Tampa, Florida);  Ertugrul Guvenkaya (Carlsbad, California);  Gokhan Mumcu (Tampa, Florida);  Huseyin Arslan (Tampa, Florida)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Mustafa Harun Yilmaz (Tampa, Florida);  Ertugrul Guvenkaya (Carlsbad, California);  Gokhan Mumcu (Tampa, Florida);  Huseyin Arslan (Tampa, Florida)
ABSTRACT System and method for determining a position of an antenna array for optimal wireless communication. The system includes a spatially adaptive and beam-steering antenna array configured to control a wireless communications path between a first element and a second element based on a determination of wireless channel gain.
FILED Friday, November 22, 2019
APPL NO 16/692216
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/12 (20130101)
H01Q 1/24 (20130101)
H01Q 1/246 (20130101)
H01Q 1/1257 (20130101)
H01Q 3/04 (20130101)
H01Q 3/26 (20130101)
H01Q 3/36 (20130101)
H01Q 3/267 (20130101)
H01Q 3/2605 (20130101) Original (OR) Class
H01Q 21/06 (20130101)
H01Q 21/22 (20130101)
H01Q 21/065 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11303347 Bendlin et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) AT and T Intellectual Property I, L.P. (Atlanta, Georgia);  University of Notre Dame du Lac (South Bend, Indiana)
ASSIGNEE(S) AT and T INTELLECTUAL PROPERTY I, L.P. (Atlanta, Georgia);  UNIVERSITY OF NOTRE DAME DU LAC (South Bend, Indiana)
INVENTOR(S) Ralf Bendlin (Cedar Park, Texas);  Aditya Chopra (Austin, Texas);  Bertrand Martyn Hochwald (South Bend, Indiana);  Nicholas Joseph Estes (South Bend, Indiana);  Jonathan David Chisum (South Bend, Indiana);  Kang Gao (San Diego, California)
ABSTRACT Aspects of the subject disclosure may include, for example, receiving an RF signal having a carrier wave component operating at a carrier frequency within a millimeter wave spectrum and an information component based on a phase modulation of the carrier wave component. The received RF signal is divided into first and second signal portions that remain in phase with respect to each other. The first signal portion is delayed by one symbol period of the phase modulation and combined with the second signal portion to obtain a combined output signal. An in-phase portion of the combined output signal is detected via a non-linear energy detector, wherein an amplitude of the first detected signal corresponds to the in-phase portion of the received RF signal. The first combined output signal includes information of the information component. Other embodiments are disclosed.
FILED Tuesday, November 24, 2020
APPL NO 17/102662
ART UNIT 2633 — Digital Communications
CURRENT CPC
Transmission
H04B 7/0837 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11303377 Giannakis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Georgios B. Giannakis (Minnetonka, Minnesota);  Xiaoli Ma (Auburn, Alabama)
ABSTRACT Techniques are described for carrier frequency offset (CFO) and channel estimation of orthogonal frequency division multiplexing (OFDM) transmissions over multiple-input multiple-output (MIMO) frequency-selective fading channels. A wireless transmitter forms blocks of symbols by inserting training symbols within two or more blocks of information-bearing symbols. The transmitter applies a hopping code to each of the blocks of symbols to insert a null subcarrier at a different position within each of the blocks of symbols, and a modulator outputs a wireless signal in accordance with the blocks of symbols. A receiver receives the wireless signal and estimates the CFO, and outputs a stream of estimated symbols based on the estimated CFO.
FILED Monday, May 18, 2020
APPL NO 16/876316
ART UNIT 2633 — Digital Communications
CURRENT CPC
Transmission
H04B 7/046 (20130101)
H04B 7/063 (20130101)
H04B 7/066 (20130101)
H04B 7/0413 (20130101)

Multiplex Communication
H04J 11/0063 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 5/0016 (20130101)
H04L 25/0202 (20130101)
H04L 25/0206 (20130101)
H04L 25/0228 (20130101)
H04L 25/0242 (20130101)
H04L 27/2607 (20130101)
H04L 27/2613 (20130101)
H04L 27/2626 (20130101)
H04L 27/2657 (20130101)
H04L 27/2671 (20130101)
H04L 27/2672 (20130101)
H04L 27/2675 (20130101)
H04L 27/2692 (20130101)
H04L 27/2695 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11298526 Carnell et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) Lisa S. Carnell (Virginia Beach, Virginia);  Emilie J. Siochi (Newport News, Virginia);  Kam W. Leong (New York, New York)
ABSTRACT A device for promoting healing of an injury in a living being is provided. Such device is based upon an injury covering portion, which portion comprises an electroactive polymer, such as poled polyvinylidine difluoride (PVDF) or a copolymer of PVDF. The electroactive polymer has either pyroelectric properties, piezoelectric properties, or both.
FILED Monday, September 09, 2019
APPL NO 16/564987
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 13/023 (20130101)
A61F 13/00051 (20130101)
A61F 2013/00936 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 15/24 (20130101)
A61L 15/24 (20130101)
A61L 15/42 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/205 (20130101)
A61N 1/0464 (20130101)
A61N 1/0468 (20130101) Original (OR) Class
A61N 1/0492 (20130101)

Compositions of Macromolecular Compounds
C08L 27/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11298675 Rezaei et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) The Curators of the University of Missouri (Columbia, Missouri)
ASSIGNEE(S) The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S) Fateme Rezaei (Rolla, Missouri);  Harshul V. Thakkar (Rolla, Missouri)
ABSTRACT Carbon dioxide (CO2) capture materials comprising one or more 3D-printed zeolite monoliths for the capture and or removal of CO2 from air or gases in enclosed compartments, including gases or mixtures of gases having less than about 5% CO2. Methods for preparing 3D-printed zeolite monoliths useful as CO2 capture materials and filters, as well as methods of removing CO2 from a gas or mixture of gases in an enclosed compartment using 3D-printed zeolite monoliths are provided.
FILED Thursday, September 20, 2018
APPL NO 16/136957
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 53/02 (20130101)
B01D 2253/11 (20130101)
B01D 2253/108 (20130101)
B01D 2253/342 (20130101)
B01D 2257/504 (20130101)
B01D 2258/06 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/12 (20130101)
B01J 20/165 (20130101) Original (OR) Class
B01J 20/2803 (20130101)
B01J 20/28071 (20130101)
B01J 2220/82 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 70/00 (20141201)
B33Y 80/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299268 Christensen et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Lance E. Christensen (Pasadena, California);  Brendan J. Smith (Merced, California);  Vlad Manzatianu (Pasadena, California)
ABSTRACT Unmanned Aerial Systems (UAS) for use in the detection, localization, and quantification of gas leaks are provided. More specifically the use of an in-situ sensor mounted to a UAS such that the sensor is positioned in a region unaffected by prop wash that is relatively undisturbed by the effects of the propeller(s) and other environmental conditions when in use is described. Additionally, methods of determining the optimal placement of the in-situ sensor on any given UAS are also provided.
FILED Thursday, November 02, 2017
APPL NO 15/801790
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Aeroplanes; Helicopters
B64C 39/024 (20130101) Original (OR) Class
B64C 2201/12 (20130101)
B64C 2201/027 (20130101)
B64C 2201/108 (20130101)
B64C 2201/141 (20130101)
B64C 2201/165 (20130101)

Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 5/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299642 Glenn
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) MORNINGBIRD MEDIA CORPORATION (Madison, Alabama)
ASSIGNEE(S) MORNINGBIRD MEDIA CORPORATION (Madison, Alabama)
INVENTOR(S) Chance M. Glenn (Madison, Alabama)
ABSTRACT A composition, method, and system for directly printing and creating complete functional 3D electronic circuits and devices without any thermal or laser post-processing treatment, by using at least Triphenylamine (TPA) as a powder binding agent. The composition can have mechanical characteristics that allow it to be melted and extruded on a structure, and electrical properties that allow it to function as at least one of a conductor, insulator, resistor, p-type semiconductor, n-type semiconductor, or capacitor.
FILED Monday, September 17, 2018
APPL NO 16/133356
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Preparation or Pretreatment of the Material to be Shaped; Making Granules or Preforms; Recovery of Plastics or Other Constituents of Waste Material Containing Plastics
B29B 11/10 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/118 (20170801)
B29C 64/291 (20170801)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2063/00 (20130101)
B29K 2067/046 (20130101)
B29K 2105/162 (20130101)
B29K 2505/14 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 70/00 (20141201)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 11/02 (20130101)
C09D 11/037 (20130101)
C09D 11/52 (20130101)
C09D 11/101 (20130101)
C09D 11/102 (20130101)
C09D 11/104 (20130101) Original (OR) Class
C09D 11/322 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/24 (20130101)
H01B 3/421 (20130101)

Resistors
H01C 17/0652 (20130101)
H01C 17/06586 (20130101)

Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 4/33 (20130101)
H01G 4/1218 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/02422 (20130101)
H01L 21/02527 (20130101)
H01L 21/02532 (20130101)
H01L 21/02601 (20130101)
H01L 21/02623 (20130101)
H01L 21/02628 (20130101)
H01L 21/02664 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 3/1283 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299776 Ellington et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Aeronautics and Space Administration (NASA)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Andrew Ellington (Austin, Texas);  Cheulhee Jung (Austin, Texas);  Sheng Cai (Zhejiang, China PRC);  Sanchita Bhadra (Austin, Texas);  John N. Milligan (Austin, Texas);  Daniel Garry (Austin, Texas);  Raghav Shroff (Austin, Texas)
ABSTRACT Disclosed are compositions and methods for nucleic acid amplification and detection. Specifically, disclosed herein are compositions and methods that allow for amplification of nucleic acids at a wide variety of temperatures. This includes a polymerase which is thermostable at high temperatures, and a method of amplification that can be conducted at relatively low temperatures.
FILED Thursday, May 10, 2018
APPL NO 16/612020
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1252 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/6853 (20130101) Original (OR) Class
C12Q 2521/101 (20130101)
C12Q 2525/301 (20130101)
C12Q 2527/101 (20130101)
C12Q 2531/101 (20130101)
C12Q 2537/1373 (20130101)
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299811 Tacconi et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Langley Research Center (LaRC)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Norma S. Tacconi (Arlington, Texas);  Wilaiwan Chanmanee (Grand Prairie, Texas);  Brian Dennis (Arlington, Texas);  Krishnan Rajeshwar (Arlington, Texas)
ABSTRACT An electrochemical reactor for use with a liquid electrolyte is capable of generating gaseous products. An electrically conducting porous layer that is hydrophilic on the catalyst side and hydrophobic on the gas side are utilized. These different surface properties promote the transport of product gases formed at the catalyst through the porous layer to the gas side. The catalyst is formed from a hybrid Cu2O—CuBr film that has a high selectivity for ethylene gas from reacting CO2 and water in an electrochemical cell.
FILED Tuesday, January 29, 2019
APPL NO 16/261484
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 3/25 (20210101)
C25B 11/031 (20210101)
C25B 11/051 (20210101)
C25B 11/091 (20210101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299820 Choi et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) Sang H. Choi (Poquoson, Virginia);  Adam J. Duzik (Yorktown, Virginia)
ABSTRACT Systems, methods, and devices of the various embodiments may provide a mechanism to enable the growth of a rhombohedral epitaxy at a lower substrate temperature by energizing the atoms in flux, thereby reducing the substrate temperature to a moderate level. In various embodiments, sufficiently energized atoms provide the essential energy needed for the rhombohedral epitaxy process which deforms the original cubic crystalline structure approximately into a rhombohedron by physically aligning the crystal structure of both materials at a lower substrate temperature.
FILED Thursday, July 27, 2017
APPL NO 15/661903
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 23/025 (20130101)
C30B 23/063 (20130101) Original (OR) Class
C30B 25/06 (20130101)
C30B 25/186 (20130101)
C30B 29/20 (20130101)
C30B 29/48 (20130101)
C30B 29/52 (20130101)
C30B 29/406 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0242 (20130101)
H01L 21/0254 (20130101)
H01L 21/02381 (20130101)
H01L 21/02433 (20130101)
H01L 21/02532 (20130101)
H01L 21/02546 (20130101)
H01L 21/02562 (20130101)
H01L 21/02609 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11300492 Bachalo et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) ARTIUM TECHNOLOGIES, INC. (Sunnyvale, California)
ASSIGNEE(S) ARTIUM TECHNOLOGIES, INC. (Sunnyvale, California)
INVENTOR(S) William D. Bachalo (Los Altos Hills, California);  Gregory A. Payne (Richland, Washington);  Khalid Ibrahim (Hatfield, Pennsylvania);  Michael J. Fidrich (San Jose, California)
ABSTRACT Methods and apparatuses to image particles are described. A plurality of illuminating light beams propagating on multiple optical paths through a particle field are generated. The plurality of illuminating light beams converge at a measurement volume. A shadow image of a particle passing through a portion of the measurement volume at a focal plane of a digital camera is imaged. Shadow images of other particles in the particle field are removed using the plurality of illuminating light beams.
FILED Tuesday, February 11, 2020
APPL NO 16/788111
ART UNIT 2877 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/12 (20130101)
G01N 15/0205 (20130101)
G01N 15/0211 (20130101)
G01N 15/0227 (20130101) Original (OR) Class
G01N 2015/03 (20130101)
G01N 2015/025 (20130101)

Image Data Processing or Generation, in General
G06T 7/60 (20130101)
G06T 7/571 (20170101)
G06T 7/593 (20170101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11303194 Jansen et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Ralph H. Jansen (Westlake, Ohio);  Peter E. Kascak (Grafton, Ohio);  Rodger W. Dyson (Elyria, Ohio)
ABSTRACT A cryogen-free partially-superconducting electric machine of the wound field synchronous type includes a room temperature semi-slotless stator, a superconducting motor rotor, a gap between the rotor and stator, a torque tube which isolates the cryogenic superconducting motor rotor from a central shaft, bearings, an acoustic cryocooler integrated within the motor rotor and torque tube, a heat exchange, a rotary transformer, a vacuum pump, a vacuum enclosure integrated with the stator, and an eddy current/thermal shield. The electric machine can act as a motor or a generator and produces a high specific power and efficiency.
FILED Tuesday, July 02, 2019
APPL NO 16/460109
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Dynamo-electric Machines
H02K 3/14 (20130101)
H02K 5/04 (20130101)
H02K 7/083 (20130101)
H02K 9/22 (20130101)
H02K 13/003 (20130101)
H02K 55/04 (20130101) Original (OR) Class
H02K 2203/15 (20130101)
H02K 2205/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 11299517 Yu et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Qingzhong Yu (Athens, Georgia);  Stephen J. Spatz (Bogart, Georgia);  John R. Dunn (East Lansing, Georgia)
ABSTRACT Provided herein are immunogenic compositions containing recombinant viruses capable of inducing protection in poultry against both Marek's disease virus (MDV) and Newcastle disease virus (NDV). Such viruses incorporate nucleic acids for expressing at least one MDV antigen, such as glycoprotein B, and antigenic portions thereof, in a recombinant NDV genome.
FILED Wednesday, April 15, 2020
APPL NO 16/848880
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 14/055 (20130101)
C07K 14/125 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11299523 Bush et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Colorado State University Research Foundation (Fort Collins, Colorado)
ASSIGNEE(S) Colorado State University Research Foundation (Fort Collins, Colorado)
INVENTOR(S) Daniel R. Bush (Fort Collins, Colorado);  Amanda K. Broz (Fort Collins, Colorado);  Bettina E. Broeckling (Fort Collins, Colorado);  Michael M. Friedman (Fort Collins, Colorado)
ABSTRACT The invention provides methods for improving plant yield, biomass accumulation and stress tolerance. A novel AP2-like transcription factor MPG1, which when modulated impacts grain yield, biomass and abiotic and biotic stress tolerance when compared to non-modulated plants. The invention further provides methods using recombinant expression cassettes, host cells, transgenic plants and breeding methods using the same.
FILED Thursday, July 06, 2017
APPL NO 16/315258
ART UNIT 1663 — Plants
CURRENT CPC
Peptides
C07K 14/415 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/827 (20130101)
C12N 15/8223 (20130101)
C12N 15/8271 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 11300542 Oxley et al.
FUNDED BY
Department of Homeland Security (DHS)
Science and Technology Directorate (DHS-S&T)
APPLICANT(S) University of Rhode Island Board of Trustees (Kingston, Rhode Island)
ASSIGNEE(S) University of Rhode Island Board of Trustees (Kingston, Rhode Island)
INVENTOR(S) Jimmie Oxley (Narragansett, Rhode Island);  James L. Smith (Narragansett, Rhode Island);  Alexander Yevdokimov (Norwich, Connecticut);  Gerald Kagan (Foxboro, Massachusetts)
ABSTRACT The present disclosure describes an improved sample preparation technique and adapter device for the removal of trace materials from swabs and delivery of the trace materials into a mass spectrometer (MS) or an ion mobility spectrometer (IMS). The adapter device and technique aids the delivery of the analyte into the instrument inlet and concurrently serves as an ionization source. The technique includes the steps of positioning or shaping the swab so that a pointed analyte release corner or tip is directed toward the inlet of the MS or IMS, adding a solvent to the swab and charging the swab to create an ionized analyte spray pointed at or positioned within the inlet of the detection instrument.
FILED Friday, February 28, 2020
APPL NO 16/804787
ART UNIT 2881 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/622 (20130101) Original (OR) Class

Electric Discharge Tubes or Discharge Lamps
H01J 49/025 (20130101)
H01J 49/0031 (20130101)
H01J 49/0409 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11301688 Ahmed et al.
FUNDED BY
Department of Homeland Security (DHS)
Transportation Security Administration (TSA)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Mohamed Nooman Ahmed (Leesburg, Virginia);  Samuel H. Woo (Reston, Virginia)
ABSTRACT A system and method for automatically detecting prohibited materials in a compartment at a security checkpoint includes receiving a three-dimensional representation of a compartment from an imaging device connected to the computing system, and classifying each voxel of the three-dimensional representation using a trained neural network to determine whether any voxel classifications of the three-dimensional representation correspond to a voxel classification of a prohibited material.
FILED Friday, June 14, 2019
APPL NO 16/441308
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 16/51 (20190101)
G06F 16/5854 (20190101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00771 (20130101) Original (OR) Class
G06K 9/6262 (20130101)
G06K 9/6268 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 11300653 Hubbert
FUNDED BY
Department of Commerce (DOC)
National Oceanic and Atmospheric Administration (NOAA)
National Science Foundation (NSF)
National Center for Atmospheric Research (NCAR)
Federally Funded Research and Development Center (FFRDC)
Operated by University Corporation for Atmospheric Research (UCAR) at Boulder, CO
APPLICANT(S) University Corporation for Atmospheric Research (Boulder, Colorado)
ASSIGNEE(S) University Corporation for Atmospheric Research (Boulder, Colorado)
INVENTOR(S) John Clark Hubbert (Fort Collins, Colorado)
ABSTRACT A method and system for removing ground clutter data from time series radar data are provided. The method comprises receiving the time series radar data, applying a clutter filter to the time series radar data to generate a filtered time series radar data, applying a discrete Fourier transform to the filtered time series radar data to generate a filtered frequency domain data, determining a filter bias for one or more filter biased frequency domain frequencies of the filtered frequency domain data based on a frequency response of the clutter filter, and correcting the filtered frequency domain data by adding the filter bias to the filtered frequency domain data at the one or more filter biased frequency domain frequencies to generate a filtered and bias corrected frequency domain data.
FILED Thursday, July 11, 2019
APPL NO 16/508858
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/288 (20130101) Original (OR) Class
G01S 7/2883 (20210501)
G01S 7/2925 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 11299993 Mittendorf et al.
FUNDED BY
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
Continuous Lower Energy, Emissions and Noise (CLEEN)
APPLICANT(S) HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey)
ASSIGNEE(S) HONEYWELL INTERNATIONAL INC. (Charlotte, North Carolina)
INVENTOR(S) Donald Mittendorf (Apache Junction, Arizona);  Krista Amato (Tempe, Arizona);  Nicole Conklin (Phoenix, Arizona);  Brent Ludwig (Mesa, Arizona);  Mark Morris (Phoenix, Arizona);  Ryon Stanley (Gilbert, Arizona);  Donald Tilman (Fountain Hills, Arizona);  Heemann Yun (Phoenix, Arizona)
ABSTRACT A turbomachine includes a shroud and a rotor, which includes first and second blades. A first blade tip and a second blade tip respectively include a base and a first layer. The second blade tip also includes an abrasive second layer layered over the respective first layer. The first layer has a lower material hardness than the shroud. The second layer has a lower thermal stability than the shroud and the first layer. The rotor performs a grind operation and, subsequently, a post-grind operation. The second layer, in the grind operation, contacts and removes material from the shroud, and wears away, thereby revealing the first layer of the second blade tip for the post-grind operation. The first layer of the first blade tip is spaced apart with at least some radial clearance from the shroud in the grind and post-grind operations.
FILED Monday, October 28, 2019
APPL NO 16/665964
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/288 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2240/30 (20130101)
F05D 2300/17 (20130101)
F05D 2300/133 (20130101)
F05D 2300/506 (20130101)
F05D 2300/611 (20130101)
F05D 2300/2282 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11298010 Bansal et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) University of Kansas (Lawrence, Kansas);  The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) University of Kansas (Lawrence, Kansas);  Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Ajay Bansal (Mission Hill, Kansas);  Lane Christenson (Leawood, Kansas);  Nick Baker (Horseshoe Bay, Texas);  Ryan Baskins (Katy, Texas);  John Stark (Lawrence, Kansas);  Nourouddin Sharifi (Schenectady, New York);  Hadi Kh A Kh Alzuabi (Ardiya, Kuwait);  Parker Gill (Overland Park, Kansas)
ABSTRACT Disclosed herein are devices having both imaging components and cell collection apparatuses. More specifically, the various embodiments disclosed herein include swallowable capsules having deployable collection structures, expansion structures to deploy the collection structures, and imaging components.
FILED Wednesday, January 31, 2018
APPL NO 16/481541
ART UNIT 3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/041 (20130101) Original (OR) Class
A61B 1/00082 (20130101)
A61B 1/00087 (20130101)
A61B 1/00094 (20130101)
A61B 1/00133 (20130101)
A61B 5/6861 (20130101)
A61B 10/0096 (20130101)
A61B 2010/0216 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 11300616 Fasig et al.
FUNDED BY
Department of Defense (DOD)
Non-Profit Organization (NPO)
Mayo Clinic (MAYO)
Mayo Foundation for Medical Education and Research (MFMER)
Special Purpose Processor Development Group (SPPDG)
National Security Agency (NSA)
APPLICANT(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Jonathan L. Fasig (Rochester, Minnesota);  Christopher K. White (Rochester, Minnesota);  Chad M. Smutzer (Rochester, Minnesota);  Michael J. Degerstrom (Rochester, Minnesota)
ABSTRACT A technique for non-invasively assessing current drawn by a device under test (DUT) by monitoring a supply voltage to the DUT. Frequency data for the DUT may be generated and used to form a current estimation model. First and second voltages are simultaneously measured using first and second test probes electrically connected to the DUT, while the first test probe is connected at a current source, and while the second test probe is connected at a DUT load that is configured to draw current from the current source. The current drawn by the DUT is then assessed by applying the current estimation model to the measured first and second voltages. In one case, the current drawn by the DUT is estimated without insertion of a circuit component into the DUT or extraction of a circuit conductor from the DUT.
FILED Wednesday, July 11, 2018
APPL NO 16/629518
ART UNIT 2851 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/31924 (20130101)
G01R 31/318357 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 11300616 Fasig et al.
FUNDED BY
Department of Defense (DOD)
Non-Profit Organization (NPO)
Mayo Clinic (MAYO)
Mayo Foundation for Medical Education and Research (MFMER)
Special Purpose Processor Development Group (SPPDG)
National Security Agency (NSA)
APPLICANT(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Jonathan L. Fasig (Rochester, Minnesota);  Christopher K. White (Rochester, Minnesota);  Chad M. Smutzer (Rochester, Minnesota);  Michael J. Degerstrom (Rochester, Minnesota)
ABSTRACT A technique for non-invasively assessing current drawn by a device under test (DUT) by monitoring a supply voltage to the DUT. Frequency data for the DUT may be generated and used to form a current estimation model. First and second voltages are simultaneously measured using first and second test probes electrically connected to the DUT, while the first test probe is connected at a current source, and while the second test probe is connected at a DUT load that is configured to draw current from the current source. The current drawn by the DUT is then assessed by applying the current estimation model to the measured first and second voltages. In one case, the current drawn by the DUT is estimated without insertion of a circuit component into the DUT or extraction of a circuit conductor from the DUT.
FILED Wednesday, July 11, 2018
APPL NO 16/629518
ART UNIT 2851 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/31924 (20130101)
G01R 31/318357 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Office of the Director of National Intelligence (ODNI) 

US 11303281 Pasandi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
ASSIGNEE(S) University of Southern California (Los Angeles, California)
INVENTOR(S) Ghasem Pasandi (Los Angeles, California);  Massoud Pedram (Beverly Hills, California)
ABSTRACT An SFQ circuit system includes at least one SFQ block having a plurality of SFQ logic gates. Characteristically, at least a portion of the SFQ logic gates are arranged in series. The SFQ circuit system includes a timing system configured to provide a first set of inputs and collect a first set of outputs of the at least one SFQ block at a rate defined by a slow clock frequency while the SFQ logic gates are clocked at a fast clock frequency. Advantageously, the rate is sufficiently slow to allow the first set of inputs to propagate through all levels of the SFQ logic gates to produce the first set of outputs of the at least one SFQ block without colliding with a second set of inputs to the at least one SFQ block.
FILED Monday, April 05, 2021
APPL NO 17/221998
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101)

Pulse Technique
H03K 19/20 (20130101)
H03K 19/096 (20130101)
H03K 19/195 (20130101) Original (OR) Class
H03K 19/17744 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11298825 Chu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Diligent Robotics, Inc. (Austin, Texas)
ASSIGNEE(S) Diligent Robotics, Inc. (Austin, Texas)
INVENTOR(S) Vivian Yaw-Wen Chu (Austin, Texas);  Shuai Li (Sammamish, Washington);  Forrest Green (Austin, Texas);  Peter Worsnop (Bethesda, Maryland);  Andrea Lockerd Thomaz (Austin, Texas)
ABSTRACT Systems, apparatus, and methods are described for robotic learning and execution of skills. A robotic apparatus can include a memory, a processor, sensors, and one or more movable components (e.g., a manipulating element and/or a transport element). The processor can be operatively coupled to the memory, the movable elements, and the sensors, and configured to obtain information of an environment, including one or more objects located within the environment. In some embodiments, the processor can be configured to learn skills through demonstration, exploration, user inputs, etc. In some embodiments, the processor can be configured to execute skills and/or arbitrate between different behaviors and/or actions. In some embodiments, the processor can be configured to learn an environmental constraint. In some embodiments, the processor can be configured to learn using a general model of a skill.
FILED Monday, October 18, 2021
APPL NO 17/504130
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 5/00 (20130101)
B25J 9/06 (20130101)
B25J 9/0081 (20130101)
B25J 9/163 (20130101)
B25J 9/1661 (20130101) Original (OR) Class
B25J 9/1694 (20130101)
B25J 11/0005 (20130101)
B25J 15/00 (20130101)
B25J 19/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 11301703 Lubin et al.
FUNDED BY
APPLICANT(S) SRI International (Menlo Park, California)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Jeffrey Lubin (Princeton, New Jersey);  James R. Bergen (Pennington, New Jersey)
ABSTRACT A biometric access control system for controlling access to an environment based on an authorization status of a living subject is disclosed. In one example, a data source generates image data of a tissue region of the subject. A liveness measurement unit processes the image data to detect changes over at least one of time or spatial volume in one or more structural features of the tissue region and generates, based on the detected changes, a spoofing attack detection status indicating that the image data is from living biological tissue or that a spoofing attack is detected. A biometric identification unit processes at least a portion of the same image data generated by the data source to generate biometric information indicative of an identity of the subject. Responsive to the spoofing attack detection status and the biometric information, an authorization unit outputs an authorization status for the subject.
FILED Wednesday, March 21, 2018
APPL NO 16/487053
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/0061 (20130101)
G06K 9/00107 (20130101)
G06K 9/00288 (20130101)
G06K 9/00906 (20130101) Original (OR) Class

Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere
G07C 9/37 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, April 12, 2022.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/details-patents-20220412.html.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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