FedInvent™ Patents
Patent Details for Tuesday, May 17, 2022
This page was updated on Thursday, May 19, 2022 at 02:12 AM GMT
Department of Health and Human Services (HHS)
| US 11330985 | Godavarty et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Anuradha Godavarty (Miami, Florida); Youngjin Jung (Miami, Florida) |
| ABSTRACT | The present application describes techniques to image biological tissue to determine biological information of an imaged tissue sample such as changes in hemoglobin concentrations, blood flow rate (pulse), and/or spatio-temporal features. Embodiments include illuminating the tissue sample with light in the near-infrared (NIR) spectrum, which is minimally absorbed but scattered through the tissue sample. By detecting the NIR light that is attenuated through, transmitted through, and/or reflected off the tissue to be imaged, the resulting NIR intensity signals may be further analyzed to provide this data. Embodiments include using multiple NIR light sources having varying wavelengths to obtain changes in the oxy- and deoxy-hemoglobin concentrations of the imaged tissue region. The tissue sample may be imaged over a time period, and the NIR images may be viewed statically or in real time after post-processing analyses have been performed. |
| FILED | Friday, February 22, 2019 |
| APPL NO | 16/282606 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0059 (20130101) A61B 5/065 (20130101) A61B 5/742 (20130101) A61B 5/02028 (20130101) Original (OR) Class A61B 5/02416 (20130101) A61B 5/7207 (20130101) A61B 5/14551 (20130101) A61B 2560/0431 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/108 (20130101) G01J 3/0264 (20130101) G01J 3/0272 (20130101) G01J 3/2823 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2021/3155 (20130101) G01N 2201/0221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331030 | He et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Bin He (Minneapolis, Minnesota); Long Yu (Minneapolis, Minnesota) |
| ABSTRACT | A system and method for cardiac activation imaging includes non-invasively or minimally invasively acquiring data about an electrical activation of a heart of a subject using at least one sensor. An activation image of the heart of the subject is reconstructed using a weighted sparse constrained reconstruction. |
| FILED | Wednesday, September 02, 2020 |
| APPL NO | 17/010264 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0044 (20130101) A61B 5/055 (20130101) A61B 5/282 (20210101) A61B 5/283 (20210101) A61B 5/316 (20210101) Original (OR) Class A61B 5/318 (20210101) A61B 5/349 (20210101) A61B 5/742 (20130101) A61B 5/6852 (20130101) A61B 5/7282 (20130101) A61B 6/032 (20130101) A61B 6/503 (20130101) A61B 6/5205 (20130101) A61B 2576/023 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331041 | Javitt et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Daniel Javitt (Fort Lee, New Jersey); Joan Prudic (New York, New York); Stefan Rowny (New York, New York); Marta Moreno (Hopewell Junction, New York) |
| ABSTRACT | An exemplary system, method and computer-accessible medium for determining an effect(s) of a convulsive stimulation therapy(ies) on a patient(s) can be provided, which can include, for example, receiving first information related to a visual network or a default mode network of a brain of the patient(s), receiving second information related to a subgenual ACC or a default mode (DMN network of the brain of the patient(s), and determining the effect(s) of the convulsive stimulation therapy(ies) based on a relationship between the first information and the second information. The convulsive stimulation therapy(ies) can be an electroconvulsive therapy or a magnetic seizure therapy. |
| FILED | Friday, March 30, 2018 |
| APPL NO | 16/499850 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/4064 (20130101) A61B 5/4848 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/38 (20130101) A61N 2/006 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/70 (20180101) G16H 30/20 (20180101) G16H 30/40 (20180101) G16H 50/20 (20180101) G16H 50/70 (20180101) G16H 70/60 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331085 | Gracias et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | David Gracias (Baltimore, Maryland); Kate Malachowski (Silver Spring, Maryland) |
| ABSTRACT | Microgrippers adapted to capture, manipulate, and contain single cells in both in vitro and in vivo cell applications are disclosed. The energy required to actuate these microgrippers is derived from the release of residual stress and does not require any wires, tethers, or batteries. Because the microgrippers are made from biocompatible and biosorbable materials, they do not accumulate in tissue. Accordingly, they can be used for in vivo applications, such as for gripping single cells in tissue biopsies. |
| FILED | Friday, October 16, 2015 |
| APPL NO | 14/885598 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/04 (20130101) A61B 10/06 (20130101) A61B 10/0233 (20130101) Original (OR) Class A61B 2010/0225 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331269 | Jin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Broad Institute, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Broad Institute, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Chengcheng Jin (Cambridge, Massachusetts); Georgia Lagoudas (Cambridge, Massachusetts); Paul Blainey (Cambridge, Massachusetts); Tyler Jacks (Newton, Massachusetts) |
| ABSTRACT | It has been discovered that lung tumor growth is associated with a dysregulation of the local microbiota, including an increased total bacterial load and reduced bacterial diversity in the airway. In the lungs, commensal bacteria, which are otherwise non-pathogenic and colonize pulmonary tissue at a much lower density in healthy individuals, provoke chronic inflammation and exacerbation of lung cancer through tumor-infiltrating immune cells. Thus, targeting the lung microbiota and its responding immune pathways is useful in treating lung cancer. Disclosed are compositions and methods targeting the lung microbiota and its responding immune pathways in a subject by specific targeting of commensal bacteria in the subject. Typically, the methods involve administering an effective amount of one or more therapeutics such as an antibiotic that reduces the local bacterial load, blocks or depletes tumor-infiltrating immune cells, and/or locally inhibits one or more cytokines or chemokines. |
| FILED | Friday, June 21, 2019 |
| APPL NO | 16/449100 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0073 (20130101) Original (OR) Class A61K 31/43 (20130101) A61K 31/4164 (20130101) A61K 31/7036 (20130101) A61K 31/7048 (20130101) A61K 31/7052 (20130101) A61K 31/7056 (20130101) A61K 38/08 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/244 (20130101) C07K 16/245 (20130101) C07K 16/2866 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331288 | Wan et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Derrick C. Wan (Stanford, California); Geoffrey C. Gurtner (Portola Valley, California); Michael T. Longaker (Atherton, California) |
| ABSTRACT | Methods of increasing perfusion and vascularity in irradiated tissue and of increasing retention of fat cells in a fat graft in irradiated tissue by applying an effective amount of DFO to the irradiated tissue at a treatment site. The DFO may be administered transdermally by applying a transdermal delivery device to a tissue surface at the treatment site in multiple discrete doses. The transdermal delivery system comprises DFO encapsulated in reverse micelles. |
| FILED | Wednesday, September 12, 2018 |
| APPL NO | 16/642467 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/1075 (20130101) A61K 31/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331297 | Song et al. |
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| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Jie Song (Atlanta, Georgia); Shuming Nie (Atlanta, Georgia); Craig Hill (Atlanta, Georgia) |
| ABSTRACT | The disclosure relates polyoxometalate complexes and uses in the management, treatment, or prevention of cancer. In certain embodiments, the polyoxometalate complexes comprise polydentate oxygen bridging ligands such as those of the following formula: [POM{(OCH2)3CX}2], [M6O13{(OCH2)3CX}2], [V6O13 {(OCH2)3CX}2], salts, or derivatives thereof wherein POM is a polyoxometalate, M is a metal, and X is defined herein. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising polyoxometalate complexes disclosed herein. |
| FILED | Thursday, October 26, 2017 |
| APPL NO | 16/345578 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/28 (20130101) Original (OR) Class A61K 31/282 (20130101) A61K 33/243 (20190101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 21/02 (20130101) Acyclic or Carbocyclic Compounds C07C 229/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/02 (20130101) C09D 5/08 (20130101) C09D 7/65 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331312 | Fagin et al. |
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| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | James A. Fagin (New York, New York); Jeffrey A. Knauf (Wappingers Falls, New York); Brian R. Untch (New York, New York) |
| ABSTRACT | The present disclosure describes a compositions and methods for treatment of Hras-driven cancers. Administration of a farnesyltransferase inhibitor, for example, tipifarnib, alone or in combination with a MEK inhibitor can reduce tumor size and tumor growth in cancers such as poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer (ATC). |
| FILED | Monday, April 27, 2015 |
| APPL NO | 15/305778 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4184 (20130101) A61K 31/4184 (20130101) A61K 31/4709 (20130101) Original (OR) Class A61K 31/4709 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11331328 — Compositions and methods for inhibiting antiapoptotic Bcl-2 proteins as anti-aging agents
| US 11331328 | Zhou et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| ASSIGNEE(S) | BioVentures, LLC (Little Rock, Arkansas) |
| INVENTOR(S) | Daohong Zhou (Little Rock, Arkansas); Yingying Wang (Little Rock, Arkansas); Jianhui Chang (Little Rock, Arkansas); Lijian Shao (Little Rock, Arkansas); Yi Luo (Little Rock, Arkansas); Wei Feng (Little Rock, Arkansas) |
| ABSTRACT | The present disclosure provides compositions and methods for selectively killing senescent cells, wherein the selective killing of senescent cells delays aging and treats age-related disorders. |
| FILED | Tuesday, May 05, 2015 |
| APPL NO | 15/308552 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/635 (20130101) Original (OR) Class A61K 31/5377 (20130101) Peptides C07K 1/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331331 | Painter et al. |
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| FUNDED BY |
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| APPLICANT(S) | EMORY UNIVERSITY (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | George R. Painter (Atlanta, Georgia); Gregory R. Bluemling (Decatur, Georgia); Michael G. Natchus (Alpharetta, Georgia); David Guthrie (Avondale Estates, Georgia) |
| ABSTRACT | This disclosure relates to certain N4-hydroxycytidine derivatives, pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of viral infections, such as Eastern, Western, and Venezuelan Equine Encephalitis (EEE, WEE and VEE, respectively), Chikungunya fever (CHIK), Ebola, Influenza, RSV, and Zika virus infection with the disclosed compounds. |
| FILED | Friday, December 07, 2018 |
| APPL NO | 16/755779 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7068 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/12 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/067 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331370 | O'Keefe et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Population Council, Inc. (New York, New York); The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The Population Council, Inc. (New York, New York); The United States of America (Bethesda, Maryland) |
| INVENTOR(S) | Barry R. O'Keefe (Frederick, Maryland); Melissa Robbiani (New York, New York); José A. Fernández Romero (Bronxville, New York) |
| ABSTRACT | Disclosed are compositions for inhibiting transmission of a sexually transmitted infection that contain one or more polyanionic microbicides, such as carrageenans, including lambda carrageenan, as well as water-soluble metal salts and specified lectins. Also disclosed are methods for making and using the compositions. |
| FILED | Tuesday, November 06, 2018 |
| APPL NO | 16/182024 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 31/717 (20130101) A61K 31/717 (20130101) A61K 31/731 (20130101) A61K 31/731 (20130101) A61K 33/04 (20130101) A61K 33/04 (20130101) A61K 33/30 (20130101) A61K 33/30 (20130101) A61K 33/34 (20130101) A61K 33/34 (20130101) A61K 36/04 (20130101) A61K 38/16 (20130101) Original (OR) Class A61K 38/168 (20130101) A61K 38/168 (20130101) A61K 45/06 (20130101) A61K 47/12 (20130101) A61K 47/14 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331373 | Zuo et al. |
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| FUNDED BY |
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| APPLICANT(S) | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (Memphis, Tennessee) |
| ASSIGNEE(S) | St. Jude Children's Research Hospital (Memphis, Tennessee) |
| INVENTOR(S) | Jian Zuo (Memphis, Tennessee); Fei Zheng (Memphis, Tennessee); Tetsuji Yamashita (Memphis, Tennessee); Wanda Layman (Germantown, Tennessee) |
| ABSTRACT | Methods and compositions using a nucleic acid molecule encoding an atonal-associated factor in combination with a co-transcription factor and/or inhibitor of a gene silencing complex to change the sensory perception of an animal are described. |
| FILED | Wednesday, January 31, 2018 |
| APPL NO | 16/483654 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 2217/052 (20130101) A01K 2217/206 (20130101) A01K 2227/105 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0046 (20130101) A61K 31/7105 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331375 | Isakson |
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| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Brant E. Isakson (Charlottesville, Virginia) |
| ABSTRACT | Inflammatory cell recruitment to local sites of tissue injury and/or infection is controlled by many signaling processes influencing cell-to-cell interactions between vascular endothelial cells (EC) in post-capillary venules and circulating leukocytes. Here we report that the ATP-release channel Pannexin1 (Panx1) opens downstream of EC activation by tumor necrosis factor α (TNF α). This process involves activation of Type 1 TNF receptors, recruitment of Src Family Kinases (SFK), and SFK-dependent phosphorylation of Panx1. We report a previously unidentified role for Panx1 channels in promoting leukocyte adhesion and emigration through the venous wall during acute systemic inflammation. The present application further discloses that Panx IL2 peptide consisting of amino acid sequence KYPIVEQYLKYGRKKQRR (SEQ ID NO: 3) or 10Panx1 peptide consisting of amino acid sequence RQAAFVDSY (SEQ ID NO: 8) are inhibitors of leukocyte adhesion. |
| FILED | Friday, July 29, 2016 |
| APPL NO | 15/746484 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) A61K 38/2013 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/00 (20180101) A61P 29/00 (20180101) Peptides C07K 14/435 (20130101) C07K 2319/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5064 (20130101) G01N 2800/328 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331377 | Maclellan et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| INVENTOR(S) | W. Robb Maclellan (Seattle, Washington); Danny El-Nachef (Seattle, Washington) |
| ABSTRACT | An expression vector capable of disrupting the silencing of cell cycle genes in adult cells, such as adult cardiac myocytes and other quiescent cells in terminally differentiated tissues, comprising: (a) a nucleic acid sequence encoding lysine-specific demethylase 4D (KDM4D); (b) a promoter that induces or effects overexpression of KDM4D, wherein the promoter is operably linked to the nucleic acid sequence; and (c) a regulatory element that inducibly represses the overexpression of KDM4D. The vector can be administered to a subject in a method for inducing tissue-specific hyperplasia in a mammal, including cardiomyocyte proliferation. The method provides for regenerative therapy, including improving cardiac function after myocardial infarct and other forms of cardiac damage. |
| FILED | Wednesday, April 20, 2016 |
| APPL NO | 15/566987 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/34 (20130101) A61K 38/00 (20130101) A61K 38/44 (20130101) Original (OR) Class A61K 48/0058 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) C12N 9/0071 (20130101) C12N 2750/14144 (20130101) Enzymes C12Y 114/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331379 | Spiegelman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Bruce M. Spiegelman (Waban, Massachusetts); James Lo (Charlestown, Massachusetts) |
| ABSTRACT | The present invention provides compositions and methods for regulating pancreatic beta cell function through modulation of adipsin activity and/or expression. Also provided are methods for preventing, treating, diagnosing, and prognosing metabolic disorders, such as diabetes, in a subject through modulation or detection of adipsin activity and/or expression. |
| FILED | Thursday, May 09, 2019 |
| APPL NO | 16/407340 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/482 (20130101) Original (OR) Class A61K 48/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Enzymes C12Y 304/21046 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 2333/4716 (20130101) G01N 2333/96433 (20130101) G01N 2800/042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331385 | Hinrichs et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Christian S. Hinrichs (Bethesda, Maryland); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | Disclosed are methods of preparing an isolated population of human papillomavirus (HPV)-specific T cells comprise dividing an HPV-positive tumor sample into multiple fragments; separately culturing the multiple fragments; obtaining T cells from the cultured multiple fragments; testing the T cells for specific autologous HPV-positive tumor recognition; selecting the T cells that exhibit specific autologous HPV-positive tumor recognition; and expanding the number of selected T cells to produce a population of HPV-specific T cells for adoptive cell therapy. Related methods of treating or preventing cancer using the T cells are also disclosed. |
| FILED | Monday, July 12, 2021 |
| APPL NO | 17/373093 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 2039/572 (20130101) A61K 2039/585 (20130101) A61K 2039/5158 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0638 (20130101) C12N 7/00 (20130101) C12N 2501/2302 (20130101) C12N 2502/30 (20130101) C12N 2710/20011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331386 | Barouch et al. |
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| FUNDED BY |
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| APPLICANT(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Dan H. Barouch (Boston, Massachusetts); Bette T. Korber (Los Alamos, New Mexico); William M. Fischer (Los Alamos, New Mexico) |
| ABSTRACT | The invention provides compositions, methods, and kits for the treatment or prevention of viral infections. The polyvalent (e.g., 2-valent) vaccines described herein incorporate computationally-optimized viral polypeptides that can increase the diversity or breadth and depth of cellular immune response in vaccinated subjects. |
| FILED | Thursday, September 10, 2020 |
| APPL NO | 16/948257 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) Original (OR) Class A61K 39/235 (20130101) A61K 39/275 (20130101) A61K 2039/53 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10043 (20130101) C12N 2710/10343 (20130101) C12N 2710/24043 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) C12N 2740/16171 (20130101) C12N 2740/16222 (20130101) C12N 2740/16234 (20130101) C12N 2740/16271 (20130101) C12N 2740/16322 (20130101) C12N 2740/16334 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331391 | McKenna et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts); University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts); University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Charles E. McKenna (Pacific Palisades, California); Boris A. Kashemirov (Los Angeles, California); Shuting Sun (Los Angeles, California); Kim Nguyen (Los Angeles, California); David Jung (Winchester, Massachusetts); Michael J. McKenna (Southborough, Massachusetts); William Sewell (Sherborn, Massachusetts); Judith Kempfle (Brookline, Massachusetts); Woo Seok Kang (Chestnut Hill, Massachusetts); Albert Edge (Brookline, Massachusetts) |
| ABSTRACT | This invention relates to drug conjugates useful for localized treatment of diseases or disorders of the middle ear and/or inner ear. Methods of treating diseases or disorders of the middle ear and/or inner ear, pharmaceutical compositions comprising the conjugates, and methods of inhibiting a Tropomyosin receptor kinase are also provided. |
| FILED | Wednesday, January 25, 2017 |
| APPL NO | 16/072456 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0046 (20130101) A61K 31/353 (20130101) A61K 31/496 (20130101) A61K 31/675 (20130101) A61K 31/7088 (20130101) A61K 47/548 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/16 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 2310/20 (20170501) C12N 2310/351 (20130101) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331415 | Oldinski et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Vermont and State Agricultural College (Burlington, Vermont) |
| ASSIGNEE(S) | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (Burlington, Vermont) |
| INVENTOR(S) | Rachael A. Oldinski (Burlington, Vermont); Jennifer N. Etter (Essex Junction, Vermont) |
| ABSTRACT | The present invention relates to the unexpected discovery of novel hydrogel formulations that allow for the encapsulation and delivery of living cells and/or drugs to a subject in need thereof. In certain embodiments, the hydrogel compositions of the invention comprise bound bioactive molecules that promote long-term cell viability and allows for the development of vasculature. The invention further provides methods of delivering viable cells and/or drugs to a subject comprising administering the compositions of the invention to the subject in need thereof. |
| FILED | Thursday, April 11, 2019 |
| APPL NO | 16/381718 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/5153 (20130101) A61K 47/36 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 31/16 (20130101) A61L 2300/64 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331463 | Damiano et al. |
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| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Edward R. Damiano (Acton, Massachusetts); Firas H. El-Khatib (Allston, Massachusetts); Rajendranath Selagamsetty (Boston, Massachusetts); Kirk D. Ramey (Tallahassee, Florida) |
| ABSTRACT | Certain embodiments provide multi-medicament infusion systems for preventing the cross-channeling of medicaments. The system may include one or more of an infusion pump, medicament reservoirs, collars, a multi-channel fluid conduit, and an infusion set. The medicament reservoirs and/or collars may be sized and shaped differently such that the medicament reservoirs can only be inserted into the system selected configurations. |
| FILED | Wednesday, December 20, 2017 |
| APPL NO | 15/848933 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/142 (20130101) A61M 5/158 (20130101) A61M 5/162 (20130101) A61M 5/1407 (20130101) A61M 5/1408 (20130101) A61M 5/14248 (20130101) A61M 39/02 (20130101) A61M 39/10 (20130101) A61M 39/105 (20130101) Original (OR) Class A61M 2005/1586 (20130101) A61M 2039/1044 (20130101) A61M 2039/1072 (20130101) A61M 2039/1094 (20130101) A61M 2205/43 (20130101) A61M 2205/583 (20130101) A61M 2205/584 (20130101) A61M 2205/6018 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331656 | Rovis et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University In The City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Tomislav Rovis (Scarsdale, New York); Cedric Theunissen (New York, New York) |
| ABSTRACT | The present disclosure provides compositions and methods for metathesizing a first alkenyl or alkynyl group with a second alkenyl or alkynyl group, the composition comprising a ruthenium metathesis catalyst and a photoredox catalyst that is activated by visible light. |
| FILED | Wednesday, October 09, 2019 |
| APPL NO | 16/597231 |
| ART UNIT | 1738 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/0275 (20130101) B01J 31/2273 (20130101) Original (OR) Class B01J 31/2291 (20130101) B01J 35/004 (20130101) B01J 2231/543 (20130101) B01J 2531/821 (20130101) Acyclic or Carbocyclic Compounds C07C 6/04 (20130101) C07C 6/06 (20130101) C07C 2531/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331659 | Sauer-Budge et al. |
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| FUNDED BY |
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| APPLICANT(S) | FRAUNHOFER USA, INC. (Plymouth, Michigan); THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | FRAUNHOFER USA, INC. (Plymouth, Michigan); CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Alexis Sauer-Budge (Lincoln, Massachusetts); Holger Wirz (Medford, Massachusetts); Samuel J. Brookfield (Boston, Massachusetts); Nira Pollock (Brookline, Massachusetts); Ronald Janzen (Aachen, Germany) |
| ABSTRACT | A pipetting device includes a housing, a valve assembly, and an actuator assembly. The housing includes a tip for receiving a capillary tube. The valve assembly includes a shuttle valve having a filling position and a dispensing position and a valve rod. The actuator assembly includes an actuator, a valve trigger, a piston mount, and an indexing mechanism. The actuator extends from the housing and has a push button coupled to a push rod. The valve trigger being configured to engage the valve assembly and includes an aperture configured to receive the piston mount therein. The indexing mechanism is configured to index a rotated position of the push button to a predefined volume of dispensed fluid. |
| FILED | Wednesday, February 14, 2018 |
| APPL NO | 16/486114 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0224 (20130101) Original (OR) Class B01L 2400/06 (20130101) B01L 2400/0478 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 9/14 (20130101) F04B 13/00 (20130101) F04B 53/109 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 35/1016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332426 | Hoveyda et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston College (Chestnut Hill, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston College (Chestnut Hill, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Amir H. Hoveyda (Lincoln, Massachusetts); Thach T. Nguyen (Newton, Massachusetts); Ming Joo Koh (Chestnut Hill, Massachusetts); Chaofan Xu (Brighton, Massachusetts); Sebastian Torker (Brighton, Massachusetts); Richard Royce Schrock (Winchester, Massachusetts) |
| ABSTRACT | Method of forming a trisubstituted ethylene compound, the method comprising: (A) providing a trisubstituted ethylene compound bearing a first, a second and a third substituent, in which the first and the second substituent are bound to the one olefinic carbon atom and are different from one another; (B) providing a monosubstituted ethylene compound or a disubstituted ethylene compound in which the substituents are vicinally bound to the olefinic carbon atoms, bearing at least a fourth substituent, respectively; (C) subjecting the trisubstituted ethylene compound provided in step (A) to a cross-metathesis reaction with olefin provided in step (B) to form said trisubstituted ethylene, wherein the cross-metathesis reaction is catalysed by a transition metal complex bearing ligands from which one ligand is a carbene ligand, wherein the carbene complex is characterized by a M=C moiety, wherein M is the transition metal; and wherein the reaction proceeds stereoselectively. |
| FILED | Friday, September 21, 2018 |
| APPL NO | 16/646479 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/2273 (20130101) B01J 2231/543 (20130101) B01J 2531/821 (20130101) Acyclic or Carbocyclic Compounds C07C 2/04 (20130101) C07C 6/02 (20130101) C07C 6/04 (20130101) C07C 41/30 (20130101) Original (OR) Class C07C 43/1787 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332432 | Swerdlow et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Russell Swerdlow (Leawood, Kansas); Laird Forrest (Fawrence, Kansas); Jordan Hunt (Lawrence, Kansas); Heather Wilkins (Kansas City, Kansas); Eli Michaelis (Lawrence, Kansas) |
| ABSTRACT | Compounds, compositions, and methods related to bioenergetic metabolism are provided. The compounds and com positions are suited to promote bioenergetic processes including cellular respiration and glycolytic flux and may be used to treat mitochondrial disorders, neurodegenerative diseases (such as Alzheimer's disease (AD), Parkinson's disease, and/or amyotrophic lateral sclerosis), multiple sclerosis, and/or epilepsy. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 17/280235 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Acyclic or Carbocyclic Compounds C07C 69/716 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332482 | Toste et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | F. Dean Toste (Piedmont, California); Mark Daniel Levin (Chicago, Illinois); James Patrick O'Neil (San Leandro, California) |
| ABSTRACT | Au(III) complexes for [18F] trifluoromethylation and methods for producing the same are disclosed. A gold complex comprises Au(CF3)2LR, wherein L comprises a solubility supporting ligand and R comprises an organic substituent. The Au(III) complex can be used to prepare a positron emitting isotope that can be used as tracers for positron emitting tomography (PET) scans. |
| FILED | Monday, May 21, 2018 |
| APPL NO | 16/615248 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0497 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332483 | Arambula et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); GEORGIA SOUTHERN UNIVERSITY (Statesboro, Georgia); WRIGHT STATE UNIVERSITY (Dayton, Ohio) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); GEORGIA SOUTHERN UNIVERSITY (Statesboro, Georgia); WRIGHT STATE UNIVERSITY (Dayton, Ohio) |
| INVENTOR(S) | Jonathan Arambula (Pooler, Georgia); Kuppuswamy Arumugam (Dayton, Ohio); Jonathan L. Sessler (Austin, Texas); Christopher Bielawski (Ulsan, South Korea) |
| ABSTRACT | The present disclosure relates gold carbene naphthoquinone compounds and salts thereof. In some aspects, these compounds can be used to treat cancer including cancers which are resistant to one or more other chemotherapeutic agents such as cisplatin or platinum chemotherapeutic agents. Also provided herein are pharmaceutical compositions comprising the gold carbene naphthoquinone compounds. |
| FILED | Friday, June 29, 2018 |
| APPL NO | 16/625023 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332485 | Burns et al. |
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| FUNDED BY |
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| APPLICANT(S) | VenatoRx Pharmaceuticals, Inc. (Malvern, Pennsylvania) |
| ASSIGNEE(S) | VENATORX PHARMACEUTICALS, INC. (Malvern, Pennsylvania) |
| INVENTOR(S) | Christopher J. Burns (Malvern, Pennsylvania); Denis Daigle (Street, Maryland); Guo-Hua Chu (Exton, Pennsylvania); Jodie Hamrick (New Holland, Pennsylvania); Matthew Lucas (Cambridge, Massachusetts); Steven A. Boyd (Chester Springs, Pennsylvania); Allison L. Zulli (Chesterbrook, Pennsylvania); Eugen F. Mesaros (Wallingford, Pennsylvania); Stephen M. Condon (Glenmoore, Pennsylvania); Robert E. Lee Trout (Collegeville, Pennsylvania); Cullen L. Myers (Exton, Pennsylvania) |
| ABSTRACT | Described herein are certain boron-containing compounds, compositions, preparations and their use as modulators of the transpeptidase function of bacterial penicillin-binding proteins and as antibacterial agents. In some embodiments, the compounds described herein inhibit penicillin-binding proteins. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections. |
| FILED | Friday, May 25, 2018 |
| APPL NO | 16/616294 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/205 (20130101) A61K 9/2009 (20130101) A61K 9/2013 (20130101) A61K 9/2018 (20130101) A61K 9/2059 (20130101) A61K 9/4858 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/027 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332499 | Haskell-Luevano et al. |
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| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Carrie Haskell-Luevano (Minneapolis, Minnesota); Mark Ericson (Minneapolis, Minnesota) |
| ABSTRACT | Certain embodiments of the invention provide a cyclic compound of formula I: wherein: Pro is a residue of L-proline; X1 is a residue of Arg or DArg; X2 is a residue of Phe or DPhe; X3 is a residue of Phe, DPhe or hPhe; X4 is a residue of a natural or unnatural amino acid; X5 is a residue of Ala, Asp, Glu, Lys, His, Phe, Ser, Leu or Gly; X6 is a residue of Phe, Ala, Gly, Ser, Lys, Asp, Leu, Nle, Trp, Tyr, Cha or hPhe; and DPro is a residue of D-proline; or a salt thereof. Certain embodiments also provide compositions comprising such compounds, as well as methods of using such compounds and compositions. |
| FILED | Thursday, August 15, 2019 |
| APPL NO | 16/542006 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) Peptides C07K 7/64 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332502 | Zolotukhin et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida); The UAB Research Foundation (Birmingham, Alabama) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida); The UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Sergei Zolotukhin (Gainesville, Florida); Sanford L. Boye (Gainesville, Florida); Shannon E. Boye (Gainesville, Florida); Damien Marsic (Rockville, Maryland); Nicholas Muzyczka (Gainesville, Florida); Hector Ruben Mendez-Gomez (Gainesville, Florida); Paul D. Gamlin (Birmingham, Alabama) |
| ABSTRACT | Adeno associated viral (AAV) particles are emerging as a useful vehicle for gene delivery to various organs and tissues, one of them being the retina. Provided here are variant AAV (e.g., variant serotype 2 (AAV2)) capsid proteins and variant capsid protein containing particles with enhanced ability to transduce retinal cells. |
| FILED | Tuesday, September 01, 2020 |
| APPL NO | 17/009536 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 15/1037 (20130101) C12N 2320/32 (20130101) C12N 2750/14011 (20130101) C12N 2750/14121 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332506 | Wisniewski et al. |
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| FUNDED BY |
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| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
| INVENTOR(S) | Thomas M. Wisniewski (Staten Island, New York); Fernando Goni (New York, New York) |
| ABSTRACT | The present invention is directed to polymerized products and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated antibodies that recognize a common conformational epitope of amyloidogenic proteins or peptides that are useful for the diagnosis, treatment, and prevention of amyloid disease. |
| FILED | Thursday, March 22, 2018 |
| APPL NO | 15/933146 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0056 (20130101) A61K 39/0007 (20130101) A61K 2039/64 (20130101) A61K 2039/523 (20130101) Peptides C07K 14/4711 (20130101) Original (OR) Class C07K 16/18 (20130101) C07K 2317/20 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 2333/4709 (20130101) G01N 2800/28 (20130101) G01N 2800/2821 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332517 | Chan et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland) |
| INVENTOR(S) | Yee-Peng Chan (Bethesda, Maryland); Christopher C. Broder (Silver Spring, Maryland) |
| ABSTRACT | The present invention relates to antibodies or antibody fragments that bind, neutralize, and/or inhibit Hendra or Nipah virus. The invention provides antibodies or antibody fragments that selectively bind to the F glycoprotein of Hendra or Nipah virus, and pharmaceutical compositions including such antibodies and/or fragments. The invention further provides polynucleotides encoding the antibodies and fragments of the invention and host cells transformed therewith. Additionally, the invention discloses prophylactic, therapeutic, and diagnostic methods employing the antibodies, fragments, polynucleotides, and/or compositions of the invention. |
| FILED | Monday, August 10, 2020 |
| APPL NO | 16/988835 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/1027 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/34 (20130101) C07K 2317/51 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/569 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332546 | Ge et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of The University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Xin Ge (Manvel, Texas); Kibaek Lee (Houston, Texas) |
| ABSTRACT | Certain embodiments provide isolated anti-MMP-14 antibodies or fragments thereof, isolated anti-MMP-12 antibodies or fragments thereof, isolated anti-BACE-1 antibodies or fragments thereof, isolated anti-Alp2 antibodies or fragments thereof, and isolated anti-cathepsin B antibodies or fragments thereof, as well as methods of use thereof. |
| FILED | Thursday, May 21, 2020 |
| APPL NO | 16/880747 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/40 (20130101) Original (OR) Class C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332712 | Ince |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| INVENTOR(S) | Tan Ince (Miami, Florida) |
| ABSTRACT | A cell culture medium comprising adenosine triphosphate; a carrier protein; cholesterol, linoleic acid, and lipoic acid; glutathione; at least one nucleotide salvage pathway precursor base; phosphoethanolamine; selenium; transferrin; triiodothyronine; all-trans-retinoic acid (ATRA) and vitamin C; zinc, magnesium, and copper; an agent that increases intracellular cAMP; epidermal growth factor (EGF); hydrocortisone; insulin; and charcoal stripped fetal bovine serum, wherein said cell culture medium is substantially free, if not entirely free, of vitamin D, androgenic hormones, androgenic ligands, estrogenic hormones, estrogenic ligands, and/or androgenic receptors. |
| FILED | Thursday, October 10, 2019 |
| APPL NO | 16/598991 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0631 (20130101) Original (OR) Class C12N 5/0693 (20130101) C12N 2500/16 (20130101) C12N 2500/20 (20130101) C12N 2500/22 (20130101) C12N 2500/24 (20130101) C12N 2500/36 (20130101) C12N 2500/38 (20130101) C12N 2500/42 (20130101) C12N 2500/46 (20130101) C12N 2501/01 (20130101) C12N 2501/11 (20130101) C12N 2501/33 (20130101) C12N 2501/39 (20130101) C12N 2501/392 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332716 | Hebrok et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); The J. David Gladstone Institutes, a testamentary trust established under the Will of J. David Gladstone (San Francisco, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); The J. David Gladstone Institutes, a testamentary trust established under the Will of J. David Gladstone (San Francisco, California) |
| INVENTOR(S) | Matthias Hebrok (Belmont, California); Holger Andreas Russ (San Francisco, California); Sheng Ding (Orinda, California); Saiyong Zhu (San Francisco, California) |
| ABSTRACT | Compositions and methods of producing mammalian cell populations that include a high proportion of pancreatic beta cells are described herein. Such cell populations are useful for treatment of diabetes. Also provided are materials and methods for the direct differentiation of stem cells, such as embryonic stem cells, into functional pancreatic beta cells. The disclosure provides the benefit of direct differentiation, which results in the production of functional pancreatic beta cells efficiently and at low cost. |
| FILED | Tuesday, July 26, 2016 |
| APPL NO | 15/747729 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/00 (20130101) A61K 35/39 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0676 (20130101) C12N 5/0677 (20130101) Original (OR) Class C12N 5/0678 (20130101) C12N 2500/22 (20130101) C12N 2500/33 (20130101) C12N 2500/38 (20130101) C12N 2501/11 (20130101) C12N 2501/91 (20130101) C12N 2501/117 (20130101) C12N 2501/155 (20130101) C12N 2501/375 (20130101) C12N 2501/395 (20130101) C12N 2501/727 (20130101) C12N 2501/999 (20130101) C12N 2506/02 (20130101) C12N 2506/22 (20130101) C12N 2513/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332717 | Gerecht et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Sharon Gerecht (Severna Park, Maryland); Xin Yi Chan (Baltimore, Maryland); Quinton Smith (Albuquerque, New Mexico); Yu-I Shen (Baltimore, Maryland) |
| ABSTRACT | Early vascular cells (EVCs), including endothelial cells and pericytes, are generated from hiPSCs. Unlike the isolated endothelial progenitor cells, the differentiated ECs mature and are functional. When encapsulated in synthetic hydrogel, EVCs respond to matrix cues and self-assembled to form three-dimensional EVCs. Moreover, these EVCs respond to hypoxic microenvironment and undergo vasculogenesis to form complex 3D networks. |
| FILED | Thursday, July 21, 2016 |
| APPL NO | 15/746477 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0024 (20130101) A61K 35/00 (20130101) A61K 35/545 (20130101) A61K 47/36 (20130101) A61K 47/42 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/069 (20130101) Original (OR) Class C12N 2500/44 (20130101) C12N 2501/165 (20130101) C12N 2501/727 (20130101) C12N 2501/999 (20130101) C12N 2506/45 (20130101) C12N 2533/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332719 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Feng Zhang (Cambridge, Massachusetts); Mark D. Brigham (Somerville, Massachusetts); Le Cong (Cambridge, Massachusetts); Silvana Konermann (Zurich, Switzerland) |
| ABSTRACT | The present invention generally relates to methods and compositions used delivery of gene editing compositions including transcriptional effectors with parvovirus and preferred methods for making same. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/213991 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 2750/14043 (20130101) C12N 2750/14121 (20130101) C12N 2750/14151 (20130101) C12N 2750/14152 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/701 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332721 | Collins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Peter L. Collins (Silver Spring, Maryland); Ursula J. Buchholz (Silver Spring, Maryland); Cindy Luongo (Bethesda, Maryland) |
| ABSTRACT | Provided herein are novel recombinant respiratory syncytial viruses (RSV) having an attenuated phenotype that contain mutations in the M2-2 open reading frame that interfere with the expression of the M2-2 protein. The M2-2 mutations may be present in combination with mutations at other loci. Using methods described herein, combinations of mutations are provided to achieve desired levels of attenuation. The recombinant RSV strains described here are suitable for use as live-attenuated RSV vaccines. Also provided are polynucleotide sequences of the described viruses, as well as methods for producing and using the viruses. |
| FILED | Monday, May 18, 2020 |
| APPL NO | 16/877277 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/155 (20130101) A61K 2039/522 (20130101) A61K 2039/543 (20130101) A61K 2039/5254 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2760/18521 (20130101) C12N 2760/18522 (20130101) C12N 2760/18534 (20130101) C12N 2760/18562 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332722 | Whitehead et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the USA as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The Government of The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Stephen S. Whitehead (Bethesda, Maryland); Joseph E. Blaney (Gettysburg, Pennsylvania); Brian R. Murphy (Bethesda, Maryland); Ching-Juh Lai (Bethesda, Massachusetts) |
| ABSTRACT | The invention is related to a dengue virus or chimeric dengue virus that contains a mutation in the 3′ untranslated region (3′-UTR) comprising a Δ30 mutation that removes the TL-2 homologous structure in each of the dengue virus serotypes 1, 2, 3, and 4, and nucleotides additional to the Δ30 mutation deleted from the 3′-UTR that removes sequence in the 5′ direction as far as the 5′ boundary of the TL-3 homologous structure in each of the dengue serotypes 1, 2, 3, and 4, or a replacement of the 3′-UTR of a dengue virus of a first serotype with the 3′-UTR of a dengue virus of a second serotype, optionally containing the Δ30 mutation and nucleotides additional to the Δ30 mutation deleted from the 3′-UTR; and immunogenic compositions, methods of inducing an immune response, and methods of producing a dengue virus or chimeric dengue virus. |
| FILED | Thursday, June 25, 2020 |
| APPL NO | 16/912359 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/5254 (20130101) Peptides C07K 14/005 (20130101) C07K 14/1825 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 7/045 (20130101) Original (OR) Class C12N 2770/24122 (20130101) C12N 2770/24162 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332729 | Romney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | David K. Romney (Pasadena, California); Javier Murciano Calles (Ubeda Jaen, Spain); Jori E. Wehrmuller (Hohenrain, Switzerland) |
| ABSTRACT | This disclosure relates to modified tryptophan synthase and more particularly to modified beta-subunits of tryptophan synthase. The disclosure further relates to cells expressing such modified subunits and methods of producing non-canonical amino acids. |
| FILED | Thursday, August 24, 2017 |
| APPL NO | 15/685839 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Heterocyclic Compounds C07D 209/20 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 13/227 (20130101) Enzymes C12Y 402/0102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332736 | Regev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Aviv Regev (Cambridge, Massachusetts); Orit Rozenblatt-Rosen (Cambridge, Massachusetts); Jellert Gaublomme (Cambridge, Massachusetts); Bo Li (Cambridge, Massachusetts); Kathryn Geiger-Schuller (Cambridge, Massachusetts); Pratiksha Thakore (Cambridge, Massachusetts) |
| ABSTRACT | The present invention provides methods and tools for analyzing genetic interactions. The subject matter disclosed herein is generally directed to single cell genomics and proteomics. In one embodiment provided is a method of cell and nuclei hashing using sample barcodes. In another embodiment are method of performing genomewide CRISPR perturbation screens. |
| FILED | Friday, December 07, 2018 |
| APPL NO | 16/770380 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332749 | Harris et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Reuben S. Harris (St. Paul, Minnesota); Daniel James Salamango (Crystal, Minnesota); Amber Renee St. Martin (Maple Grove, Minnesota) |
| ABSTRACT | Real-time systems for monitoring base editing in living cells, including base editing by APOBEC-Cas9 fusions, is provided herein. |
| FILED | Friday, July 13, 2018 |
| APPL NO | 16/035286 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/00 (20130101) C07K 14/43504 (20130101) C07K 14/43595 (20130101) C07K 16/12 (20130101) C07K 16/18 (20130101) C07K 2317/24 (20130101) C07K 2319/00 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/78 (20130101) C12N 15/63 (20130101) C12N 15/86 (20130101) C12N 15/102 (20130101) C12N 15/102 (20130101) C12N 15/635 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2740/16043 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 2521/539 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332754 | Daniell |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Henry Daniell (Media, Pennsylvania) |
| ABSTRACT | Methods for improving transgene in chloroplasts are disclosed along with improved transgenes so produced and methods of use thereof for the treatment of disease. Specifically, the methods comprising analyzing the native sequence of a nucleic acid encoding a protein of interest and replacing codons in said sequence with those preferentially used in psbA genes in chloroplasts in higher plants. |
| FILED | Monday, March 20, 2017 |
| APPL NO | 16/086416 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0058 (20130101) A61K 39/12 (20130101) A61K 2039/542 (20130101) A61K 2039/545 (20130101) A61K 2039/575 (20130101) A61K 2039/6037 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/02 (20180101) A61P 31/14 (20180101) Peptides C07K 14/65 (20130101) C07K 14/755 (20130101) C07K 14/4723 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/2408 (20130101) C12N 15/8214 (20130101) C12N 15/8216 (20130101) C12N 15/8257 (20130101) C12N 15/8258 (20130101) Original (OR) Class C12N 2770/32634 (20130101) Enzymes C12Y 302/01084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332756 | Balachandran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Institute For Cancer Research (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Institute For Cancer Research (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Siddharth Balachandran (Philadelphia, Pennsylvania); Roshan Thapa (Philadelphia, Pennsylvania) |
| ABSTRACT | RNA virus vectors comprising a gene encoding the DNA-dependent activator of interferon-regulatory factors (DAI) protein, and optionally further comprising a gene encoding the receptor-interacting serine/threonine-protein kinase 3 (RIPK3) may be used therapeutically to induce cell death, as well as an inflammatory immune response, against tumors and virally-infected cells. |
| FILED | Wednesday, July 05, 2017 |
| APPL NO | 16/315420 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) A61K 2039/585 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/04 (20180101) Peptides C07K 14/47 (20130101) C07K 14/4705 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2760/16121 (20130101) C12N 2760/16132 (20130101) C12N 2760/16143 (20130101) Enzymes C12Y 207/11001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332783 | Metsky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Hayden Metsky (Cambridge, Massachusetts); Andreas Gnirke (Cambridge, Massachusetts); Christian Matranga (Cambridge, Massachusetts); Daniel Park (Cambridge, Massachusetts); Pardis Sabeti (Cambridge, Massachusetts) |
| ABSTRACT | The present invention provides a combination of genomic and computational technologies to provide rapid, portable sample analysis for sequencing or identifying a target sequence involving generating probes for use in analyzing a sample which may comprise a target sequence. |
| FILED | Friday, August 26, 2016 |
| APPL NO | 15/756546 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 1/701 (20130101) C12Q 1/6806 (20130101) C12Q 1/6809 (20130101) C12Q 1/6816 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332789 | Yang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Temple University-Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Temple University-Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Xiao-Feng Yang (Huntingdon Valley, Pennsylvania) |
| ABSTRACT | The invention provides compositions and methods for the diagnosis, treatment, assessment, and characterization of hyperlipidemia-related diseases and disorders, including atherosclerosis, non-alcoholic fatty liver disease, obesity and diabetes mellitus in a subject in need thereof, based on the expression level of at least one miRNA that is associated with these diseases and disorders. |
| FILED | Tuesday, May 21, 2019 |
| APPL NO | 16/417987 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6806 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332794 | Powell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | Wayne State University (Detroit, Michigan) |
| INVENTOR(S) | Isaac J. Powell (Detroit, Michigan); Aliccia Bollig-Fischer (Detroit, Michigan); Greg Dyson (Northville, Michigan) |
| ABSTRACT | The use of genes or biomarkers to more accurately diagnose aggressive prostate cancer in men of African descent or European descent is provided. More specifically, the genes or biomarkers of the present invention can be used in diagnostic tests and methods to determine, qualify, and/or assess aggressive prostate cancer or status, for example, to diagnose or identify aggressive prostate cancer, in an individual, subject, or patient, such as men of African descent or men of European descent. |
| FILED | Thursday, January 19, 2017 |
| APPL NO | 16/071325 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) G01N 2800/7028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333646 | Potyrailo |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Niskayuna, New York) |
| INVENTOR(S) | Radislav Alexandrovich Potyrailo (Niskayuna, New York) |
| ABSTRACT | A gas sensor system includes a gas sensing element that includes a gas sensing material and electrodes configured to apply electrical stimuli to the gas sensing material and one or more processors configured to control the gas sensing element. The one or more processors are configured to direct the electrodes to apply the electrical stimuli at two or more different electrical excitation frequencies to the gas sensing material. A first electrical excitation frequency of the two or more different electrical excitation frequencies is configured to provide a quantitative gas response of the gas sensing material, the quantitative gas response including a response drift. A second electrical excitation frequency of the two or more different electrical excitation frequencies is configured to provide a baseline response of the gas sensing material based at least in part on the response drift. |
| FILED | Wednesday, June 05, 2019 |
| APPL NO | 16/432050 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/6801 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/02 (20130101) G01N 27/04 (20130101) G01N 27/026 (20130101) G01N 27/221 (20130101) G01N 31/223 (20130101) Original (OR) Class G01N 33/0031 (20130101) G01N 33/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333655 | Aksimentiev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); Technische Universiteit Delft (Delft, Netherlands) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); TECHNISCHE UNIVERSITEIT DELFT (Delft, Netherlands) |
| INVENTOR(S) | Aleksei Aksimentiev (Urbana, Illinois); Cornelis Dekker (Delft, Netherlands) |
| ABSTRACT | Aspects of the subject disclosure may include, for example, an apparatus comprising: a membrane having a first side and a second side, wherein the membrane has first and second pores disposed therein, a processing system; and a memory that stores executable instructions that, when executed by the processing system, facilitate performance of operations comprising: setting a first physical characteristic in a vicinity of the first pore to cause a first end of a molecule having the first end and a second end to be moved through the first pore; setting a second physical characteristic in a vicinity of the second pore to cause the second end of the molecule to be moved through the second pore; and adjusting the first physical characteristic to cause the molecule to be tightened, with a first given amount of force, between the first pore and the second pore. Additional embodiments are disclosed. |
| FILED | Wednesday, September 06, 2017 |
| APPL NO | 15/697202 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44791 (20130101) G01N 33/48721 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333667 | Tong |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SAN DIEGO STATE UNIVERSITY FOUNDATION (San Diego, California) |
| ASSIGNEE(S) | SAN DIEGO STATE UNIVERSITY FOUNDATION (San Diego, California) |
| INVENTOR(S) | William G. Tong (La Jolla, California) |
| ABSTRACT | This patent document discloses techniques, systems, and devices for detecting a target substance using optical nonlinear wave mixing for enhanced detection sensitivity and accuracy. In one aspect, a method for measuring α-synuclein in a body fluid of a patient with high detection sensitivity and accuracy and providing early stage Parkinson's disease detection is provided. The method may comprise: supplying to a capillary analyte cell a fluidic sample that includes a body fluid of a patient containing α-synuclein, wherein the capillary analyte cell is located in a nonlinear optical four-wave mixing device; directing laser light from the nonlinear optical four-wave mixing device into the capillary analyte cell to cause nonlinear optical four-wave mixing in the fluidic sample to generate a four-wave mixing signal that contains information on the α-synuclein in the fluidic sample; and processing the four-wave mixing signal to extract information on the α-synuclein in the fluidic sample. |
| FILED | Tuesday, February 21, 2017 |
| APPL NO | 15/999856 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/03 (20130101) G01N 21/636 (20130101) G01N 21/718 (20130101) G01N 27/44791 (20130101) G01N 33/49 (20130101) G01N 33/582 (20130101) Original (OR) Class G01N 33/6896 (20130101) G01N 2021/0346 (20130101) G01N 2800/56 (20130101) G01N 2800/2835 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333668 | Merbl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Yifat Merbl (Jamaica Plain, Massachusetts); Marc W. Kirschner (Newton, Massachusetts) |
| ABSTRACT | Methods for the large scale identification of post-translational modification states of proteins and enzyme activities for carrying out post-translational modification reactions involve the analysis of functional extracts from fresh and frozen samples using protein arrays. The methods and kits of the present invention can be used to analyze and characterize compounds for their effects on post-translational modifications and their pathways. The methods and kits can also be used to diagnose and characterize a wide variety of diseases and medical conditions, including cancer, neurodegenerative diseases, immune diseases, infectious diseases, genetic diseases, metabolic conditions, and drug effects using cells or body fluids of a patient. |
| FILED | Friday, July 10, 2015 |
| APPL NO | 14/796408 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6842 (20130101) G01N 33/6845 (20130101) Original (OR) Class G01N 33/57484 (20130101) G01N 2440/00 (20130101) G01N 2440/14 (20130101) G01N 2440/36 (20130101) G01N 2800/00 (20130101) G01N 2800/28 (20130101) G01N 2800/2821 (20130101) G01N 2800/2835 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333669 | Coon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Joshua J. Coon (Middleton, Wisconsin); Alex Hebert (Madison, Wisconsin) |
| ABSTRACT | The invention provides mass spectrometry methods, compositions and systems which enable a unique platform for analyte quantitation accessing very high degrees of multiplexing and accurate quantification, particularly well-suited for a range of quantitative analysis for proteomics applications. Embodiments of the present methods and systems combine isotopic coding agents characterized by very small differences in molecular mass with mass spectrometry methods providing large resolving power to provide relative or absolute analyte quantification in a large number of samples. |
| FILED | Friday, May 13, 2016 |
| APPL NO | 15/154514 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) Original (OR) Class G01N 2458/15 (20130101) G01N 2560/00 (20130101) G01N 2570/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/24 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333730 | Saggar |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Manish Saggar (Stanford, California) |
| ABSTRACT | Systems and methods for mapping neuronal circuitry in accordance with embodiments of the invention are illustrated. One embodiment includes a method for generating a neuronal shape graph, including obtaining functional brain imaging data from an imaging device, where the functional brain imaging data includes a time-series of voxels describing neuronal activation over time in a patient's brain, lowering the dimensionality of the functional brain imaging data to a set of points, where each point represents the brain state at a particular time in the timeseries, binning the points into a plurality of bins, clustering the binned points, and generating a shape graph from the clustered points, where nodes in the shape graph represent a brain state and edges between the nodes represent transitions between brain states. |
| FILED | Thursday, October 25, 2018 |
| APPL NO | 16/171255 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/16 (20130101) A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/165 (20130101) A61B 5/369 (20210101) A61B 5/743 (20130101) A61B 5/4064 (20130101) A61B 5/7264 (20130101) A61B 2576/026 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) Original (OR) Class G01R 33/5608 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6224 (20130101) G06K 9/6297 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/50 (20170101) G06T 2207/10088 (20130101) G06T 2207/30016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333874 | Hillman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Elizabeth M. C. Hillman (New York, New York); Venkatakaushik Voleti (Cupertino, California) |
| ABSTRACT | In some embodiments of SCAPE imaging systems, a Powell lens is used to expand light from a light source into a sheet of illumination light. An optical system sweeps the sheet of illumination light through a sample, and forms an image at an intermediate image plane from detected return light. A camera captures images of the intermediate image plane. In some embodiments of SCAPE imaging systems, an optical system sweeps the sheet of illumination light through a sample, and forms an image at an intermediate image plane from detected return light. A camera captures images of the intermediate image plane. In the latter embodiments, the optical system is deliberately misaligned with respect to a true alignment position so that a significant portion of light that would be lost at the true alignment position will arrive at the camera. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/206778 |
| ART UNIT | 2484 — Recording and Compression |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/22 (20130101) Original (OR) Class G02B 21/0032 (20130101) G02B 21/082 (20130101) G02B 21/361 (20130101) G02B 27/095 (20130101) G02B 27/0927 (20130101) G02B 27/0955 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11336473 | Yeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Edmund Meng Yeh (Newton, Massachusetts); Milad Mahdian (New York, New York) |
| ABSTRACT | Embodiments include a unified framework for minimizing congestion-dependent network cost by jointly optimizing forwarding and caching strategies that account for link congestion between neighboring nodes. As caching variables are integer-constrained, the resulting optimization problem is a non-deterministic polynomial time (NP)-hard problem. Embodiments relax the optimization problem, where caching variables are real-valued. Embodiments include optimality conditions for the relaxed problem. Embodiments include an adaptive and distributed joint forwarding and caching method, based on a conditional gradient method. Embodiments elegantly yield feasible routing variables and integer caching variables at each iteration, and can be implemented in a distributed manner with low complexity and overhead. Over a wide range of network topologies, simulation results show that embodiments have significantly better delay performance in the low to moderate request rate regions. Furthermore, embodiments complement each other in delivering superior delay performance across the range of request arrival rates, compared to existing methods. |
| FILED | Friday, October 12, 2018 |
| APPL NO | 16/754067 |
| ART UNIT | 2469 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 12/1432 (20130101) Original (OR) Class H04L 67/32 (20130101) H04L 67/2842 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11336823 | Alshurafa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Nabil I. Alshurafa (Chicago, Illinois); Josiah D. Hester (Evanston, Illinois) |
| ABSTRACT | A camera system includes a camera configured to capture first video of a scene in the form of first image frames. The camera system also includes an infrared sensor configured to capture second video of the scene in the form of second image frames. The system also includes a processor in communication with the camera and the infrared sensor. The processor is configured to obfuscate one or more portions of the scene. |
| FILED | Wednesday, September 02, 2020 |
| APPL NO | 17/010560 |
| ART UNIT | 2481 — Recording and Compression |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/003 (20130101) G06T 5/50 (20130101) G06T 7/194 (20170101) G06T 2207/10024 (20130101) G06T 2207/10048 (20130101) G06T 2207/20221 (20130101) Pictorial Communication, e.g Television H04N 5/76 (20130101) H04N 5/247 (20130101) H04N 5/272 (20130101) H04N 5/2252 (20130101) H04N 5/2253 (20130101) H04N 5/23229 (20130101) Original (OR) Class H04N 7/18 (20130101) H04N 9/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11331020 | Galagan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | James Galagan (Needham, Massachusetts); Mark W. Grinstaff (Brookline, Massachusetts); Uros Kuzmanovic (Brookline, Massachusetts); Mingfu Chen (Boston, Massachusetts); Margarita Alexandrovna Tararina (Bryn Mawr, Pennsylvania); Karen Nazaretian Allen (Weston, Massachusetts) |
| ABSTRACT | Described herein is an amperometric biosensor, e.g., chronoamperometric biosensor for the measurement of the concentration of nicotine. Also disclosed herein is a wearable nicotine biosensor device and a biosensor that detects nicotine in smoke. The biosensor disclosed herein comprises a nicotine-catalyzing enzyme, such as NicA2 or mutant NicA2 enzymes. Also described herein are systems comprising said amperometric biosensor, e.g., chronoamperometric biosensor and methods of using said chronoamperometric biosensor. |
| FILED | Friday, February 05, 2021 |
| APPL NO | 17/169193 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1486 (20130101) Original (OR) Class A61B 5/4845 (20130101) A61B 5/14517 (20130101) A61B 10/0064 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/004 (20130101) C12Q 1/005 (20130101) C12Q 1/26 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3272 (20130101) G01N 33/48714 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331269 | Jin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Broad Institute, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Broad Institute, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Chengcheng Jin (Cambridge, Massachusetts); Georgia Lagoudas (Cambridge, Massachusetts); Paul Blainey (Cambridge, Massachusetts); Tyler Jacks (Newton, Massachusetts) |
| ABSTRACT | It has been discovered that lung tumor growth is associated with a dysregulation of the local microbiota, including an increased total bacterial load and reduced bacterial diversity in the airway. In the lungs, commensal bacteria, which are otherwise non-pathogenic and colonize pulmonary tissue at a much lower density in healthy individuals, provoke chronic inflammation and exacerbation of lung cancer through tumor-infiltrating immune cells. Thus, targeting the lung microbiota and its responding immune pathways is useful in treating lung cancer. Disclosed are compositions and methods targeting the lung microbiota and its responding immune pathways in a subject by specific targeting of commensal bacteria in the subject. Typically, the methods involve administering an effective amount of one or more therapeutics such as an antibiotic that reduces the local bacterial load, blocks or depletes tumor-infiltrating immune cells, and/or locally inhibits one or more cytokines or chemokines. |
| FILED | Friday, June 21, 2019 |
| APPL NO | 16/449100 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0073 (20130101) Original (OR) Class A61K 31/43 (20130101) A61K 31/4164 (20130101) A61K 31/7036 (20130101) A61K 31/7048 (20130101) A61K 31/7052 (20130101) A61K 31/7056 (20130101) A61K 38/08 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/244 (20130101) C07K 16/245 (20130101) C07K 16/2866 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331331 | Painter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | EMORY UNIVERSITY (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | George R. Painter (Atlanta, Georgia); Gregory R. Bluemling (Decatur, Georgia); Michael G. Natchus (Alpharetta, Georgia); David Guthrie (Avondale Estates, Georgia) |
| ABSTRACT | This disclosure relates to certain N4-hydroxycytidine derivatives, pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of viral infections, such as Eastern, Western, and Venezuelan Equine Encephalitis (EEE, WEE and VEE, respectively), Chikungunya fever (CHIK), Ebola, Influenza, RSV, and Zika virus infection with the disclosed compounds. |
| FILED | Friday, December 07, 2018 |
| APPL NO | 16/755779 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7068 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/12 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/067 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331373 | Zuo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (Memphis, Tennessee) |
| ASSIGNEE(S) | St. Jude Children's Research Hospital (Memphis, Tennessee) |
| INVENTOR(S) | Jian Zuo (Memphis, Tennessee); Fei Zheng (Memphis, Tennessee); Tetsuji Yamashita (Memphis, Tennessee); Wanda Layman (Germantown, Tennessee) |
| ABSTRACT | Methods and compositions using a nucleic acid molecule encoding an atonal-associated factor in combination with a co-transcription factor and/or inhibitor of a gene silencing complex to change the sensory perception of an animal are described. |
| FILED | Wednesday, January 31, 2018 |
| APPL NO | 16/483654 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 2217/052 (20130101) A01K 2217/206 (20130101) A01K 2227/105 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0046 (20130101) A61K 31/7105 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331391 | McKenna et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts); University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts); University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Charles E. McKenna (Pacific Palisades, California); Boris A. Kashemirov (Los Angeles, California); Shuting Sun (Los Angeles, California); Kim Nguyen (Los Angeles, California); David Jung (Winchester, Massachusetts); Michael J. McKenna (Southborough, Massachusetts); William Sewell (Sherborn, Massachusetts); Judith Kempfle (Brookline, Massachusetts); Woo Seok Kang (Chestnut Hill, Massachusetts); Albert Edge (Brookline, Massachusetts) |
| ABSTRACT | This invention relates to drug conjugates useful for localized treatment of diseases or disorders of the middle ear and/or inner ear. Methods of treating diseases or disorders of the middle ear and/or inner ear, pharmaceutical compositions comprising the conjugates, and methods of inhibiting a Tropomyosin receptor kinase are also provided. |
| FILED | Wednesday, January 25, 2017 |
| APPL NO | 16/072456 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0046 (20130101) A61K 31/353 (20130101) A61K 31/496 (20130101) A61K 31/675 (20130101) A61K 31/7088 (20130101) A61K 47/548 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/16 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 2310/20 (20170501) C12N 2310/351 (20130101) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331392 | Koberstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Jeffrey T. Koberstein (Cataumet, Massachusetts); Sanjoy Samanta (Selmabad, India); Chathuranga De Silva (New York, New York) |
| ABSTRACT | The invention provides for novel thermo-responsive polymers and compositions comprising the same. In some embodiments, the polymers are water soluble, pH-degradable and have tunable lower critical solution temperatures. Other aspects of the invention include micelles and gels comprising the thermo-responsive polymers and derivatives thereof, as well as methods of delivering therapeutic agents comprising administering a biodegradable gel or micelle comprising a polyacetal compound cross-linked with a linker. |
| FILED | Thursday, December 03, 2015 |
| APPL NO | 15/532405 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/04 (20130101) A01N 25/10 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/1075 (20130101) A61K 31/7068 (20130101) A61K 47/59 (20170801) A61K 47/60 (20170801) Original (OR) Class A61K 47/6907 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/18 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/48 (20130101) C08G 65/33396 (20130101) C08G 81/00 (20130101) C08G 2230/00 (20130101) C08G 2650/04 (20130101) C08G 2650/30 (20130101) C08G 2650/44 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/24 (20130101) C08J 3/075 (20130101) C08J 2371/08 (20130101) Compositions of Macromolecular Compounds C08L 33/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331410 | Francis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | EMBODY, INC. (Norfolk, Virginia) |
| ASSIGNEE(S) | EMBODY, INC. (Norfolk, Virginia) |
| INVENTOR(S) | Michael Francis (Norfolk, Virginia); Nathan Kemper (Norfolk, Virginia); Hilary Wriggers (Norfolk, Virginia) |
| ABSTRACT | Compositions and blends of biopolymers and copolymers are described, along with their use to prepare biocompatible scaffolds and surgically implantable devices for use in supporting and facilitating the repair of soft tissue injuries. |
| FILED | Thursday, August 19, 2021 |
| APPL NO | 17/406409 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 38/39 (20130101) A61K 47/34 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) Original (OR) Class A61L 27/24 (20130101) A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/44 (20130101) A61L 27/54 (20130101) A61L 27/58 (20130101) A61L 27/386 (20130101) A61L 27/3804 (20130101) A61L 2300/64 (20130101) A61L 2300/604 (20130101) A61L 2400/12 (20130101) A61L 2430/10 (20130101) A61L 2430/34 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) C08L 89/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331627 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Qilin Li (Houston, Texas); Jinjian Wu (Costa Mesa, California); Nancy C. Halas (Houston, Texas); Katherine R. Zodrow (Butte, Montana); Haoli Guo (Beijing, China PRC); Jiarui Xu (Houston, Texas); Cong Yu (Issaquah, Washington) |
| ABSTRACT | In some embodiments, the present disclosure pertains to systems and methods for distilling a fluid by exposing the fluid to a porous membrane that includes a surface capable of generating heat. In some embodiments, the heat generated at the surface propagates the distilling of the fluid by converting the fluid to a vapor that flows through the porous membrane and condenses to a distillate. In some embodiments, the surface capable of generating heat is associated with a photo-thermal composition that generates the heat at the surface by converting light energy from a light source to thermal energy. In some embodiments, the photo-thermal composition includes, without limitation, noble metals, semiconducting materials, dielectric materials, carbon-based materials, composite materials, nanocomposite materials, nanoparticles, hydrophilic materials, polymers, fibers, meshes, fiber meshes, hydrogels, hydrogel meshes, nanomaterials, and combinations thereof. Further embodiments pertain to methods of making the porous membranes of the present disclosure. |
| FILED | Monday, October 19, 2020 |
| APPL NO | 17/074305 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/364 (20130101) Original (OR) Class B01D 67/0088 (20130101) B01D 71/021 (20130101) B01D 71/022 (20130101) B01D 2313/36 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331789 | Penn |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James Douglass Penn (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James Douglass Penn (Cambridge, Massachusetts) |
| ABSTRACT | A system and method for a planar positioning system for an output member, the system having a pair of x-coordinate linear carriages and a pair of y-coordinate linear carriages. The system has a guide mechanism for the pair of x-coordinate linear carriages and the pair of y-coordinate linear carriages. The system has a plurality of movement and constraining cables extending from the pair of x-coordinate linear carriages and the pair of y-coordinate linear carriages to the output member for driving the output, wherein the pair of x-coordinate linear carriages and the output member move in sync in the x-direction and the pair of y-coordinate linear carriages and the output member move in sync in the y-direction. A restraint mechanism restrains the output member in an additional degree of freedom besides the x- and y-directions. The restraint can be a cable uptake and release device. |
| FILED | Monday, June 01, 2015 |
| APPL NO | 14/727851 |
| ART UNIT | 3658 — Material and Article Handling |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/023 (20130101) Original (OR) Class B25J 9/026 (20130101) B25J 9/1045 (20130101) Gearing F16H 2019/069 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/21 (20130101) Technical Subjects Covered by Former US Classification Y10T 74/20341 (20150115) Y10T 74/20354 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332245 | Mohseni et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Kamran Mohseni (Gainesville, Florida); Thomas I. Linehan (Gainesville, Florida) |
| ABSTRACT | A vehicle, such as a micro-aerial vehicle or underwater vehicle, includes at least one lift structure, such as a low-aspect-ratio wing or a fin, respectively. The at least one lift structure comprises one or more alulas. A leading surface of each alula is (a) flush with a leading surface of the lift structure or (b) offset from the leading edge of the lift surface by up to approximately 10% of the chord length of the lift structure. The length of each alula is no more than approximately 20% of a lift structure length corresponding to the lift structure. In various embodiments, the alula is deflected or canted with respect to a plane defined by the lift structure. In an example embodiment, the alulas may be slid or translated along at least a portion of the span of the lift structure. |
| FILED | Tuesday, December 10, 2019 |
| APPL NO | 16/709227 |
| ART UNIT | 3619 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 9/08 (20130101) B64C 9/22 (20130101) B64C 23/06 (20130101) B64C 39/028 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332253 | Yakimenko |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Oleg Yakimenko (Seaside, California) |
| ABSTRACT | The disclosure provides an HAPR apparatus comprising an inflatable frame configured to generate canopy extension based on surrounding atmospheric pressure. The inflatable frame has a first collapse load limit less than the weight of the canopy at a first pressurized state less than 75 kPa and a second collapse load limit greater than the weight of the canopy at a second pressurized state of greater than 95 kPa. The internal pressure of the inflatable frame is typically about 101 kPa. The HAPR apparatus allows ascension with the canopy hanging under its own weight to reduce ascension time, then generates canopy extension prior to release in essentially a zero velocity, zero dynamic pressure condition. |
| FILED | Thursday, December 26, 2019 |
| APPL NO | 16/727656 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Lighter-than Air Aircraft B64B 1/48 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 17/02 (20130101) B64D 17/26 (20130101) B64D 17/72 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332383 | Anguiano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Gary Anguiano (Oxnard, California); Dennis How (Camarillo, California); Mark Foreman (Santa Barbara, California) |
| ABSTRACT | A modular porous swale. The modular porous swale may comprise a porous concrete block and filtration joint. The porous concrete block may snugly fit within a trench having a lower portion filled with an absorption media. The absorption media may include gravel, activated alumina, bone char, or an activated alumina and bone char mixture. The porous concrete block may have a top surface inwardly-sloped to a nadir. The filtration joint may be disposed within the porous concrete block and along the nadir. The liner may cover one or more sides of the porous concrete block. The perforated pipe may be located within the absorption media. The filtration joint may substantially align above a portion of the perforated pipe when the modular porous swale is installed within the trench. |
| FILED | Thursday, December 10, 2020 |
| APPL NO | 17/117244 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 15/10 (20130101) B01D 39/14 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/004 (20130101) Original (OR) Class C02F 1/281 (20130101) C02F 1/283 (20130101) C02F 2103/001 (20130101) C02F 2201/004 (20130101) Construction Of, or Surfaces For, Roads, Sports Grounds, or the Like; Machines or Auxiliary Tools for Construction or Repair E01C 11/225 (20130101) Hydraulic Engineering E02B 11/00 (20130101) Sewers; Cesspools E03F 1/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332484 | Bardon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Akita Innovations LLC (Billerica, Massachusetts) |
| ASSIGNEE(S) | Akita Innovations LLC (Billerica, Massachusetts) |
| INVENTOR(S) | Kevin M. Bardon (Somerville, Massachusetts); Richard A. Minns (Arlington, Massachusetts); Scott D. Selfridge (Hudson, New Hampshire); Larry Takiff (Woburn, Massachusetts); Timothy Adams (Howell, New Jersey) |
| ABSTRACT | Voltage sensitive dyes comprising boron and related compositions and methods are provided. In some embodiments, a voltage sensitive dye comprises an electron acceptor comprising boron. The electron acceptor may be attached (e.g., covalently) to at least one electron donating group and at least one polar group. For instance, the electron acceptor may comprise optionally substituted boron dipyrromethene (e.g., optionally substituted 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene). The point of attachment and chemical nature of the electron donating group(s) and polar group(s) may be selected to impart beneficial properties to the voltage sensitive dye. For instance, the voltage sensitive dye may have an extended difference in the dipole moment between the ground and electronic states due at least in part to the position of the electron donating group(s). The voltage sensitive dyes, described herein, may have high specificity, high signal to noise ratio, fast responsivity, high voltage sensitivity, high photostability, and/or high brightness. |
| FILED | Friday, March 02, 2018 |
| APPL NO | 16/490467 |
| ART UNIT | 1699 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0071 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/006 (20130101) A61K 49/0017 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/022 (20130101) Original (OR) Class Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/1029 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332493 | Gracias et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | David H. Gracias (Baltimore, Maryland); Thao D. Nguyen (Baltimore, Maryland); ChangKyu Yoon (Timonium, Maryland); Rebecca B. Schulman (Baltimore, Maryland); Angelo Cangialosi (Baltimore, Maryland); Ruohong Shi (Baltimore, Maryland) |
| ABSTRACT | Described are a combinatorial library of DNA molecules that can induce shape changes within specific regions of hydrogels up to centimeter scales. The DNA molecules include polymerizing hairpins, terminating hairpins, reversal strands, and crosslink nucleic acid sequences. |
| FILED | Friday, August 31, 2018 |
| APPL NO | 16/634994 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/7007 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/26 (20130101) A61L 27/52 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/00 (20130101) Original (OR) Class Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332517 | Chan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland) |
| INVENTOR(S) | Yee-Peng Chan (Bethesda, Maryland); Christopher C. Broder (Silver Spring, Maryland) |
| ABSTRACT | The present invention relates to antibodies or antibody fragments that bind, neutralize, and/or inhibit Hendra or Nipah virus. The invention provides antibodies or antibody fragments that selectively bind to the F glycoprotein of Hendra or Nipah virus, and pharmaceutical compositions including such antibodies and/or fragments. The invention further provides polynucleotides encoding the antibodies and fragments of the invention and host cells transformed therewith. Additionally, the invention discloses prophylactic, therapeutic, and diagnostic methods employing the antibodies, fragments, polynucleotides, and/or compositions of the invention. |
| FILED | Monday, August 10, 2020 |
| APPL NO | 16/988835 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/1027 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/34 (20130101) C07K 2317/51 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/569 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332747 | Liu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Augusta University Research Institute, Inc. (Augusta, Georgia) |
| ASSIGNEE(S) | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. (Augusta, Georgia) |
| INVENTOR(S) | Hongyan Liu (Martinez, Georgia) |
| ABSTRACT | Bispecific aptamers having a first end that specifically binds to a first tumor specific marker, tumor antigen, or viral protein and a second end that specifically binds to a second tumor specific marker, tumor antigen, or viral protein are provide. The bispecific aptamers can be used to treat cancer or virally infected cells. Generally, the bispecific aptamers bind to two surface proteins, preferably different proteins, on the same cell. In a preferred embodiment the bispecific aptamers bind to two different tumor markers, tumor antigens, tumor specific proteins and combinations thereof. |
| FILED | Tuesday, February 20, 2018 |
| APPL NO | 15/899473 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333074 | Orr |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aerojet Rocketdyne, Inc. (Sacramento, California) |
| ASSIGNEE(S) | AEROJET ROCKETDYNE, INC. (Sacramento, California) |
| INVENTOR(S) | Neil H. Orr (Sacramento, California) |
| ABSTRACT | A liquid propellant rocket engine includes a pump that is disposed along a central axis. The pump includes a purge system, a collection annulus in fluid communication with the purge system, and a drain. The collection annulus has an outer diameter wall, an inner diameter wall, and an end wall. The end wall defines an annular channel that has a channel depth that varies circumferentially. The drain opens to the collection annulus. At the drain, the annular channel has a lowest point at which the channel depth is maximum depth. |
| FILED | Wednesday, July 26, 2017 |
| APPL NO | 16/316703 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/32 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/222 (20130101) F02C 7/232 (20130101) Original (OR) Class Jet-propulsion Plants F02K 9/48 (20130101) F02K 9/54 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/292 (20130101) F05D 2250/294 (20130101) F05D 2250/314 (20130101) F05D 2260/6022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333103 | Bender |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Norman Harold Bender (Mercer Island, Washington) |
| ABSTRACT | A nozzle having a forward portion skewed downwards and an aft portion translated downwards provides sufficient clearance between the nozzle and the heat shield structure to prevent contact in the event of large deflections (e.g., as associated with a fan blade Out (FBO) condition). Such large deflections must be accounted for to meet federal aviation regulations and gain airplane CFR 14 Part 25 Certification. |
| FILED | Friday, May 17, 2019 |
| APPL NO | 16/415310 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 33/04 (20130101) Jet-propulsion Plants F02K 1/52 (20130101) F02K 1/82 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333104 | Borissov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FireFly Aerospace Inc. (Cedar Park, Texas) |
| ASSIGNEE(S) | FireFly AeroSpace Inc. (Cedar Park, Texas) |
| INVENTOR(S) | Anatoli Alimpievich Borissov (Sugar Land, Texas); Thomas Edward Markusic (Georgetown, Texas) |
| ABSTRACT | A liquid rocket engine cools a thruster body by pumping propellant through cooling channels integrated in the thruster body between internal and external surfaces. One or more of the cooling channel surfaces has a variable depth along a thrust axis to mix propellant flow and destroy thermal stratification, such as a depth that varies with a repeated contiguous sinusoidal form along the thrust axis. Fuel passed through the cooling channels injects from the combustion chamber wall towards a central portion of the combustion chamber to cross impinge with oxygen injected at the combustion chamber head so that a toroidal vortex forms to enhance propellant mixing. |
| FILED | Thursday, January 24, 2019 |
| APPL NO | 16/256206 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/00 (20130101) Jet-propulsion Plants F02K 9/42 (20130101) F02K 9/52 (20130101) Original (OR) Class F02K 9/62 (20130101) F02K 9/64 (20130101) F02K 9/425 (20130101) F02K 9/972 (20130101) Supplying Air or Non-combustible Liquids or Gases to Combustion Apparatus in General; Valves or Dampers Specially Adapted for Controlling Air Supply or Draught in Combustion Apparatus; Inducing Draught in Combustion Apparatus; Tops for Chimneys or Ventilating Shafts; Terminals for Flues F23L 7/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333499 | Endean |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Daniel Endean (Plymouth, Minnesota) |
| ABSTRACT | A gyroscope assembly includes a sense proof mass and a compensation proof mass. The sense proof mass has a sense frequency response in a sense dimension and is configured to move in a drive dimension in response to a drive signal, and to move in the sense dimension in response to experiencing an angular velocity about a sense input axis while moving in the drive dimension. And the compensation proof mass has, in the sense dimension, a compensation frequency response that is related to the sense frequency response. |
| FILED | Monday, July 08, 2019 |
| APPL NO | 16/505340 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/5614 (20130101) Original (OR) Class G01C 19/5621 (20130101) G01C 19/5684 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333548 | Lal |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Amit Lal (Ithaca, New York) |
| ABSTRACT | A device configured for low-energy ultrasonic 2D Fourier transform analysis, comprising: (i) a first layer comprising an array of piezoelectric pixels; (ii) a second layer comprising an array of piezoelectric pixels; (iii) a third layer, positioned between the first and second layers, comprising a bulk ultrasonic transmission medium; wherein the second layer of array of piezoelectric pixels is in the Fourier plane of an input signal of the first layer array of piezoelectric pixels. |
| FILED | Thursday, May 23, 2019 |
| APPL NO | 17/057868 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 11/08 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/46 (20130101) G01N 2291/0426 (20130101) Electric Digital Data Processing G06F 17/142 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/18 (20130101) H01L 41/083 (20130101) Transmission H04B 11/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333601 | Jang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Woo Yong Jang (Xenia, Ohio); Nathan E. Zechar (Mason, Ohio); James Park (Fairborn, Ohio); Andrew J. Hamilton (Dayton, Ohio) |
| ABSTRACT | A method of determining a refractive index of a material sample comprises removably mounting the material sample into a sample holder having a thermal control mechanism, a thermal expansion compensation mechanism, and a rotation mechanism; projecting a laser beam into the material sample, wherein the material sample has a predetermined orientation and temperature, wherein the material sample has parallel sides defining parallel planes for entry and exit of the laser beam into and out of the material sample; collecting a refracted laser beam from the material sample, and determining the refractive index for the material sample at the predetermined temperature. The laser beam may be a visible laser and/or an infrared laser. The thermal control mechanism comprises a thermal controller coupled to an induction coil apparatus and a temperature sensor. The sample holder comprises a refractory metal consisting of one or more of a niobium/molybdenum alloy and a tantalum/tungsten alloy. |
| FILED | Wednesday, April 14, 2021 |
| APPL NO | 17/229897 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/43 (20130101) G01N 21/4133 (20130101) Original (OR) Class G01N 2021/414 (20130101) G01N 2021/432 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333663 | Swager et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Timothy Manning Swager (Newton, Massachusetts); Joseph Michael Azzarelli (Cambridge, Massachusetts); Shinsuke Ishihara (Cambridge, Massachusetts) |
| ABSTRACT | A tag for detecting an analyte can include a radio frequency identification tag including a sensor portion, the sensor portion configured to change resistivity when the radio frequency identification tag contacts or interacts with an analyte, whereby the resistivity change alters an output of the radio frequency identification tag, wherein the sensor portion includes a circuit, and wherein the sensor portion is configured to activate the circuit or deactivate the circuit when contacted or having interacted with the analyte, where the sensor portion includes a plurality of carbon nanotubes associated with a chemically-degradable polymer. In certain embodiments, the chemically degradable polymer can be a metallo-supramolecular polymer. |
| FILED | Thursday, May 07, 2020 |
| APPL NO | 16/869534 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/21 (20130101) G01N 21/78 (20130101) G01N 21/6428 (20130101) G01N 33/54386 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/07 (20130101) G06K 19/0717 (20130101) G06K 19/0723 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333667 | Tong |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SAN DIEGO STATE UNIVERSITY FOUNDATION (San Diego, California) |
| ASSIGNEE(S) | SAN DIEGO STATE UNIVERSITY FOUNDATION (San Diego, California) |
| INVENTOR(S) | William G. Tong (La Jolla, California) |
| ABSTRACT | This patent document discloses techniques, systems, and devices for detecting a target substance using optical nonlinear wave mixing for enhanced detection sensitivity and accuracy. In one aspect, a method for measuring α-synuclein in a body fluid of a patient with high detection sensitivity and accuracy and providing early stage Parkinson's disease detection is provided. The method may comprise: supplying to a capillary analyte cell a fluidic sample that includes a body fluid of a patient containing α-synuclein, wherein the capillary analyte cell is located in a nonlinear optical four-wave mixing device; directing laser light from the nonlinear optical four-wave mixing device into the capillary analyte cell to cause nonlinear optical four-wave mixing in the fluidic sample to generate a four-wave mixing signal that contains information on the α-synuclein in the fluidic sample; and processing the four-wave mixing signal to extract information on the α-synuclein in the fluidic sample. |
| FILED | Tuesday, February 21, 2017 |
| APPL NO | 15/999856 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/03 (20130101) G01N 21/636 (20130101) G01N 21/718 (20130101) G01N 27/44791 (20130101) G01N 33/49 (20130101) G01N 33/582 (20130101) Original (OR) Class G01N 33/6896 (20130101) G01N 2021/0346 (20130101) G01N 2800/56 (20130101) G01N 2800/2835 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333798 | Raeker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents Of The University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Brian Raeker (Ann Arbor, Michigan); Anthony Grbic (Ann Arbor, Michigan) |
| ABSTRACT | A compound metaoptic is presented. The compound metaoptic is comprised of at least two phase-discontinuous metasurfaces, which can convert an incident light beam to an aperture field with a desired magnitude, phase, and polarization profile. Each of the constitutive metasurfaces is designed to exhibit specific refractive properties, which vary along the metasurface. Furthermore, due to its transmission-based operation, the metaoptic can operate without lenses and be low profile: potentially having a thickness on the order of a few wavelengths or less. A systematic design procedure is also presented, which allows conversion between arbitrary complex-valued field distributions without reflection, absorption or active components. Such compound metaoptics may find applications where a specific complex field distribution is desired, including displaying holographic images and augmented or virtual reality systems. |
| FILED | Wednesday, July 03, 2019 |
| APPL NO | 16/502817 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) Original (OR) Class G02B 5/3025 (20130101) Holographic Processes or Apparatus G03H 1/02 (20130101) G03H 2001/0216 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11334107 | Carolan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jacques Johannes Carolan (Cambridge, Massachusetts); Mihika Prabhu (Cambridge, Massachusetts); Scott A. Skirlo (Boston, Massachusetts); Yichen Shen (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts); Dirk Englund (Brookline, Massachusetts); Nicholas Christopher Harris (Boston, Massachusetts) |
| ABSTRACT | An optical neural network is constructed based on photonic integrated circuits to perform neuromorphic computing. In the optical neural network, matrix multiplication is implemented using one or more optical interference units, which can apply an arbitrary weighting matrix multiplication to an array of input optical signals. Nonlinear activation is realized by an optical nonlinearity unit, which can be based on nonlinear optical effects, such as saturable absorption. These calculations are implemented optically, thereby resulting in high calculation speeds and low power consumption in the optical neural network. |
| FILED | Thursday, August 06, 2020 |
| APPL NO | 16/986383 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/212 (20210101) G02F 1/225 (20130101) G02F 1/365 (20130101) G02F 1/3526 (20130101) G02F 3/024 (20130101) G02F 2202/32 (20130101) G02F 2203/15 (20130101) Optical Computing Devices; G06E 3/005 (20130101) Original (OR) Class G06E 3/006 (20130101) G06E 3/008 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) G06N 3/084 (20130101) G06N 3/0675 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11334344 | Graham et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Andrew Graham (Havre de Grace, Maryland); Raymond Steeley (Bel Air, Maryland); Eugene Thompson (Oxford, Pennsylvania); Thomas Rinaldi (Aberdeen Proving Ground, Maryland); Christopher Myers (West Grove, Pennsylvania) |
| ABSTRACT | Various embodiments that pertain to device software is described. A decision can be made by a device on if the device should download an update for device software, such as a software patch. When the device decides that it should download the update, the device can download the appropriate update. In one example, the update can be downloaded by way of a patch portal that communicates with a patch database. The device can request the patch for the software and in response the device can be provided access to the patch by way of the patch portal. |
| FILED | Tuesday, April 28, 2020 |
| APPL NO | 16/860445 |
| ART UNIT | 2192 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 8/658 (20180201) Original (OR) Class G06F 21/30 (20130101) G06F 21/57 (20130101) Computer Systems Based on Specific Computational Models G06N 5/025 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 47/805 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11334360 | Hu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DEEPBITS TECHNOLOGY INC. (Riverside, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | DEEPBITS TECHNOLOGY INC. (Riverside, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Xunchao Hu (Riverside, California); Sheng Yu (Riverside, California); Heng Yin (Riverside, California) |
| ABSTRACT | The present invention performs high-throughput disassembly for executable code comprising a plurality of instructions. An input of the executable code is received. Exhaustive disassembly is performed on the executable code to produce a set of exhaustively disassembled instructions. An instruction flow graph is constructed from the exhaustively disassembled instructions. Instruction embedding is performed on the exhaustively disassembled instructions to construct embeddings. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/243570 |
| ART UNIT | 2182 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 8/53 (20130101) G06F 9/3838 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11334516 | Payment |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Venturi, LLC (Huntsville, Alabama) |
| ASSIGNEE(S) | Venturi, LLC (Huntsville, Alabama) |
| INVENTOR(S) | Benjamin Victor Payment (Huntsville, Alabama) |
| ABSTRACT | This disclosure relates generally to systems and methods of translating between Universal Serial Bus (USB) and synchronous serial protocols. In one embodiment, an apparatus includes an application-specific integrated circuit (ASIC) configured to operate in a multi-protocol generic mode and in an adaptive clock mode. The ASIC is configured to implement a multi-protocol generic command processor in the multi-protocol generic mode where the ASIC is operable to be commanded so as to execute a generic bus command that converts between the USB protocol and any commanded synchronous serial protocol. Furthermore, the ASIC can synchronize the execution of the generic bus command with an externally generated clock signal on the synchronous serial side when the ASIC is also provided in the adaptive clock mode. In this manner, a computer device with a USB port can use the ASIC as a bridge for data communications with a radio having a synchronous serial port. |
| FILED | Monday, July 13, 2020 |
| APPL NO | 16/927014 |
| ART UNIT | 2181 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 1/10 (20130101) G06F 13/4282 (20130101) Original (OR) Class G06F 2213/0042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11334716 | Beller et al. |
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| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles E. Beller (Baltimore, Maryland); Christopher F. Ackermann (Fairfax, Virginia); Kristen Maria Summers (Takoma Park, Maryland); David McQuenney (Yorktown Heights, New York); Rob High (Round Rock, Texas) |
| ABSTRACT | Embodiments relate to an intelligent computer platform to selectively amend one or more tokens in a document. A first document set is subjected to natural language processing (NLP) and a vector score is identified for two or more documents of the first document set. Upon receipt of a new document, the new document is subjected to NLP and a new document vector score is identified. The new document is analyzed against the first document set, and the identified vector score of the first document set is compared to the vector score of the new document. One or more tokens of the new document are amended responsive to the comparison, and a new document version is created from the selective amendment. |
| FILED | Monday, September 09, 2019 |
| APPL NO | 16/564014 |
| ART UNIT | 2659 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 40/30 (20200101) G06F 40/44 (20200101) G06F 40/205 (20200101) G06F 40/253 (20200101) G06F 40/284 (20200101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11335026 | Bramlett et al. |
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| FUNDED BY |
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| APPLICANT(S) | Science Applications International Corporation (Reston, Virginia) |
| ASSIGNEE(S) | Science Applications International Corporation (Reston, Virginia) |
| INVENTOR(S) | Stephen Eric Bramlett (Gurley, Alabama); Michael Harris Rodgers (Huntsville, Alabama) |
| ABSTRACT | Search points in a search space may be projected onto images from cameras imaging different parts of the search space. Subimages, corresponding to the projected search points, may be selected and processed to determine if a target object has been detected. Based on subimages in which target objects are detected, as well as orientation data from cameras capturing images from which the subimages were selected, positions of the target objects in the search space may be determined. |
| FILED | Monday, February 03, 2020 |
| APPL NO | 16/779917 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/3233 (20130101) G06K 9/3241 (20130101) G06K 9/4671 (20130101) G06K 9/6202 (20130101) Image Data Processing or Generation, in General G06T 3/4038 (20130101) G06T 7/33 (20170101) G06T 7/74 (20170101) Original (OR) Class G06T 7/80 (20170101) G06T 7/246 (20170101) G06T 2207/10016 (20130101) G06T 2207/20021 (20130101) G06T 2207/30244 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11335457 | Brown et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Kayla N. Brown (Hillsboro, Ohio); Melissa A. Wilson (Hillsboro, Ohio); Brittany L. Fouts (Fairborn, Ohio) |
| ABSTRACT | Various embodiments of the disclosed subject matter provide systems, methods, architectures, mechanisms, apparatus and/or computer implemented method configured for automatically managing En Route Care (ERC) transport patient and medical equipment loading. |
| FILED | Wednesday, December 11, 2019 |
| APPL NO | 16/710030 |
| ART UNIT | 3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 40/20 (20180101) Original (OR) Class G16H 40/67 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11335513 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUTECH VENTURES (Lincoln, Nebraska) |
| INVENTOR(S) | Jinsong Huang (Lincoln, Nebraska); Xiaopeng Zheng (Lincoln, Nebraska) |
| ABSTRACT | Semiconductor devices, and methods of forming the same, include a cathode layer, an anode layer, and an active layer disposed between the cathode layer and the anode layer, wherein the active layer includes a perovskite layer. A passivation layer is disposed directly on a surface of the active layer between the cathode layer and the active layer, the passivation layer including a layer of material that passivates both cationic and anionic defects in the surface of the active layer. |
| FILED | Friday, August 16, 2019 |
| APPL NO | 16/542712 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/0036 (20130101) H01G 9/2009 (20130101) Original (OR) Class H01G 9/2018 (20130101) H01G 9/2059 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0003 (20130101) H01L 51/0035 (20130101) H01L 51/0046 (20130101) H01L 51/0072 (20130101) H01L 51/0077 (20130101) H01L 51/424 (20130101) H01L 51/442 (20130101) H01L 51/448 (20130101) H01L 51/4213 (20130101) H01L 51/4253 (20130101) H01L 2251/301 (20130101) H01L 2251/308 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11335529 | Jensen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Kevin Jensen (Washington, District of Columbia); Michael McDonald (Washington, District of Columbia) |
| ABSTRACT | A compound field emitter (CFE) includes a first surface possessing a field enhancement factor >1, and a second surface possessing one or both of a field enhancement factor >1, or a low work function, wherein the second surface is coated, formed or applied upon the first surface. The second surface has a characteristic size at least 3 times smaller than the first surface, and the outer surface includes a coating of calcium aluminate 12CaO-7Al2O3. |
| FILED | Monday, June 21, 2021 |
| APPL NO | 17/353703 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 1/304 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11335649 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia) |
| ASSIGNEE(S) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia) |
| INVENTOR(S) | Jun Wang (Blacksburg, Virginia); Rolando Burgos (Blacksburg, Virginia); Dushan Boroyevich (Blacksburg, Virginia); Joshua Stewart (Blacksburg, Virginia); Yue Xu (Falls Church, Virginia) |
| ABSTRACT | Various embodiments of laminated planar bus structures that minimize electromagnetic interference (EMI) and parasitic inductance are described. In one embodiment, a laminated planar bus structure may include a plurality of stacked conductive layers and a plurality of stacked insulation layers. The plurality of stacked conductive layers may include positive and negative conductive layers, and conductive ground layers stacked as outer layers as to enclose vertically the positive and the negative conductive layers. In another embodiment, the laminated planar bus structure may include a middle ground layer stacked in between the positive and the negative conductive layers to provide additional reduction in electric field strength. A laminated planar bus structure that is integrated with other power electronics components is also presented. |
| FILED | Wednesday, May 20, 2020 |
| APPL NO | 16/879078 |
| ART UNIT | 2899 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/50 (20130101) H01L 23/60 (20130101) Original (OR) Class H01L 23/5227 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11335781 | Eom et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Chang-Beom Eom (Madison, Wisconsin); Daesu Lee (Madison, Wisconsin) |
| ABSTRACT | Heterostructures that include a bilayer composed of epitaxial layers of vanadium dioxide having different rutile-to-monoclinic phase transition temperatures are provided. Also provided are electrical switches that incorporate the heterostructures. The bilayers are characterized in that they undergo a single-step, collective, metal-insulator transition at an electronic transition temperature. At temperatures below the electronic transition temperature, the layer of vanadium dioxide having the higher rutile-to-monoclinic phase transition temperature has an insulating monoclinic crystalline phase, which is converted to a metallic monoclinic crystalline phase at temperatures above the electronic transition temperature. |
| FILED | Wednesday, May 10, 2017 |
| APPL NO | 15/591454 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/24 (20130101) Original (OR) Class H01L 29/45 (20130101) H01L 29/94 (20130101) H01L 29/7869 (20130101) H01L 29/8611 (20130101) H01L 45/04 (20130101) H01L 45/146 (20130101) H01L 45/1226 (20130101) H01L 45/1233 (20130101) H01L 45/1253 (20130101) H01L 49/003 (20130101) Pulse Technique H03K 17/687 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11335846 | Hutchison et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Geoffrey R. Hutchison (Pittsburgh, Pennsylvania); Michael James Moody (Pittsburgh, Pennsylvania) |
| ABSTRACT | A material that includes a polymer foam and at least one polar dopant molecule included in the polymer foam, wherein the material is a piezoelectric. |
| FILED | Monday, January 30, 2017 |
| APPL NO | 16/074730 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Characteristic Features of Footwear; Parts of Footwear A43B 3/34 (20220101) A43B 17/003 (20130101) A43B 17/14 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/4829 (20130101) C08G 18/7671 (20130101) C08G 2110/0016 (20210101) C08G 2410/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/00 (20130101) C08J 9/0014 (20130101) C08J 9/0023 (20130101) C08J 9/0028 (20130101) C08J 2205/08 (20130101) C08J 2375/08 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/01 (20130101) C08K 5/09 (20130101) C08K 5/32 (20130101) C08K 2201/001 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/12 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/08 (20130101) H01L 41/45 (20130101) H01L 41/193 (20130101) Original (OR) Class H01L 41/257 (20130101) H01L 41/1132 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11336377 | Papp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado); Government of the United States of America as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado); Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| INVENTOR(S) | Scott B. Papp (Boulder, Colorado); Jizhao Zang (Boulder, Colorado) |
| ABSTRACT | A millimeter-wave frequency synthesizer generates a millimeter wave by photomixing two Kerr-soliton microcombs. A single-frequency laser beam is modulated to create first and second pump components having first and second pump frequencies. The first pump component excites a first microresonator to create a first microcomb while the second pump component excites a second microresonator to generate a second microcomb. A pair of comb lines from the two microcombs is detected to generate a low-frequency beat note that is phase-locked by identically tuning the pump frequencies. Another pair of comb lines is detected with a high-speed photodiode to generate the millimeter wave. The frequency of the millimeter wave is based on (i) the difference between the pump frequencies, (ii) the difference between the repetition rates, and (iii) the index of the comb lines that are photomixed to generate the millimeter wave. |
| FILED | Tuesday, July 27, 2021 |
| APPL NO | 17/443647 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Transmission H04B 10/54 (20130101) H04B 10/58 (20130101) Original (OR) Class H04B 10/548 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11336476 | Klenk et al. |
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| FUNDED BY |
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| APPLICANT(S) | NVIDIA Corporation (Santa Clara, California) |
| ASSIGNEE(S) | NVIDIA Corporation (Santa Clara, California) |
| INVENTOR(S) | Benjamin Klenk (San Jose, California); Nan Jiang (Santa Clara, California); Larry Robert Dennison (Menden, Massachusetts); Gregory M. Thorson (Palo Alto, California) |
| ABSTRACT | A network device configured to perform scalable, in-network computations is described. The network device is configured to process pull requests and/or push requests from a plurality of endpoints connected to the network. A collective communication primitive from a particular endpoint can be received at a network device. The collective communication primitive is associated with a multicast region of a shared global address space and is mapped to a plurality of participating endpoints. The network device is configured to perform an in-network computation based on information received from the participating endpoints before forwarding a response to the collective communication primitive back to one or more of the participating endpoints. The endpoints can inject pull requests (e.g., load commands) and/or push requests (e.g., store commands) into the network. A multicast capability enables tasks, such as a reduction operation, to be offloaded to hardware in the network device. |
| FILED | Friday, July 24, 2020 |
| APPL NO | 16/938156 |
| ART UNIT | 2415 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 9/5083 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 12/18 (20130101) H04L 12/1886 (20130101) Original (OR) Class H04L 45/74 (20130101) H04L 47/20 (20130101) H04L 47/39 (20130101) H04L 47/806 (20130101) H04L 67/26 (20130101) H04L 67/2842 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11331019 | Zhong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| INVENTOR(S) | Chuan-Jian Zhong (Endwell, New York); Mark D. Poliks (Vestal, New York); Benjamin S. Hsiao (Setauket, New York); Ning Kang (Vestal, New York); Shan Yan (Vestal, New York); Jing Li (Vestal, New York); Shiyao Shan (Vestal, New York); Jin Luo (Vestal, New York) |
| ABSTRACT | Nanoparticle-fibrous membrane composites are provided as tunable interfacial scaffolds for flexible chemical sensors and biosensors by assembling gold nanoparticles (Au NPs) in a fibrous membrane. The gold nanoparticles are functionalized with organic, polymeric and/or biological molecules. The fibrous membranes may include different filter papers, with one example featuring a multilayered fibrous membrane consisting of a cellulose nanofiber (CN) top layer, an electrospun polyacrylonitrile (PAN) nanofibrous midlayer (or alternate material), and a nonwoven polyethylene terephthalate (PET) fibrous support layer, with the nanoparticles provided on the fibrous membranes through interparticle molecular/polymeric linkages and nanoparticle-nanofibrous interactions. Molecular linkers may be employed to tune hydrogen bonding and electrostatic and/or hydrophobic/hydrophilic interactions to provide sensor specificity to gases or liquids. The sensors act as chemiresistor-type sensors. A preferred implementation is a sweat sensor. |
| FILED | Tuesday, August 07, 2018 |
| APPL NO | 16/057314 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/082 (20130101) A61B 5/145 (20130101) A61B 5/1477 (20130101) Original (OR) Class A61B 5/4266 (20130101) A61B 5/14517 (20130101) A61B 2560/0412 (20130101) A61B 2562/12 (20130101) A61B 2562/0285 (20130101) A61B 2562/0295 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331020 | Galagan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | James Galagan (Needham, Massachusetts); Mark W. Grinstaff (Brookline, Massachusetts); Uros Kuzmanovic (Brookline, Massachusetts); Mingfu Chen (Boston, Massachusetts); Margarita Alexandrovna Tararina (Bryn Mawr, Pennsylvania); Karen Nazaretian Allen (Weston, Massachusetts) |
| ABSTRACT | Described herein is an amperometric biosensor, e.g., chronoamperometric biosensor for the measurement of the concentration of nicotine. Also disclosed herein is a wearable nicotine biosensor device and a biosensor that detects nicotine in smoke. The biosensor disclosed herein comprises a nicotine-catalyzing enzyme, such as NicA2 or mutant NicA2 enzymes. Also described herein are systems comprising said amperometric biosensor, e.g., chronoamperometric biosensor and methods of using said chronoamperometric biosensor. |
| FILED | Friday, February 05, 2021 |
| APPL NO | 17/169193 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1486 (20130101) Original (OR) Class A61B 5/4845 (20130101) A61B 5/14517 (20130101) A61B 10/0064 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/004 (20130101) C12Q 1/005 (20130101) C12Q 1/26 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3272 (20130101) G01N 33/48714 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331027 | Sniadecki et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Nathan J. Sniadecki (Bothell, Washington); Shiv Bhandari (Seattle, Washington); Kevin S. Bielawski (Seattle, Washington); Andrea B. Leonard (Seattle, Washington); Charles E. Murry (Seattle, Washington) |
| ABSTRACT | Devices and techniques for magnetic detection of myocardial forces are generally described. In some examples, cardiac tissue may be cultured such that the cardiac tissue adheres to a first post and a second post. In further examples, a magnetometer may detect a change in a magnetic field resulting from a deflection of the first post in a first direction from a first position to a second position. In some other examples a signal corresponding to the change in the magnetic field may be generated. In still other examples, frequencies of the signal outside of a first frequency range may be excluded to produce a filtered signal. In various examples, the first frequency range may include frequencies associated with beating of cardiac tissue. In still further examples, a force exerted by the cardiac tissue may be determined based at least in part on the filtered signal. |
| FILED | Friday, March 10, 2017 |
| APPL NO | 16/082847 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/243 (20210101) Original (OR) Class A61B 5/7203 (20130101) A61B 5/7225 (20130101) A61B 2503/02 (20130101) A61B 2562/0223 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 35/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/72 (20130101) G01N 33/4833 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331277 | Gu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Zhen Gu (Raleigh, North Carolina); Xiuli Hu (Raleigh, North Carolina) |
| ABSTRACT | Disclosed herein is a nanoparticle comprising a copolymer comprising a polyethylene glycol polymer, a polyhydroxylated polymer, and a peroxide-sensitive pendant group; a glucose-responsive agent; and a therapeutic agent; wherein the copolymer encapsulates the glucose-responsive agent and the therapeutic agent. Also disclosed herein is a method of delivering a therapeutic agent to a subject comprising administering to the subject a nanoparticle comprising a copolymer comprising a polyethylene glycol polymer, a polyhydroxylated polymer, and a peroxide-sensitive pendant group; a glucose-responsive agent; and a therapeutic agent; wherein the copolymer encapsulates the glucose-responsive agent and the therapeutic agent; and releasing the therapeutic agent from the nanoparticle in the presence of hyperglycemic levels of glucose. In some embodiments, the glucose-responsive agent produces a peroxide when exposed to hyperglycemic levels of glucose, thereby triggering disassembly of the nanoparticle and release of encapsulated therapeutic agent. |
| FILED | Tuesday, December 05, 2017 |
| APPL NO | 16/466695 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0021 (20130101) A61K 9/1075 (20130101) A61K 9/5146 (20130101) Original (OR) Class A61K 38/28 (20130101) A61K 47/34 (20130101) A61K 47/36 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331367 | Baker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| INVENTOR(S) | Bill J. Baker (Temple Terrace, Florida); Nerida G. Wilson (Cottesloe, Australia); John H. Adams (Tampa, Florida); Matthew A. Knestrick (Washington, District of Columbia); Alison Elizabeth Roth (North Bethesda, Maryland) |
| ABSTRACT | Described herein are compounds, formulations, and methods for blocking sporozoite invasion and subsequent liver-stage parasite development of a protozoan parasite, such as Plasmodium falciparum. |
| FILED | Monday, December 23, 2019 |
| APPL NO | 16/725182 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4706 (20130101) A61K 38/08 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331392 | Koberstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Jeffrey T. Koberstein (Cataumet, Massachusetts); Sanjoy Samanta (Selmabad, India); Chathuranga De Silva (New York, New York) |
| ABSTRACT | The invention provides for novel thermo-responsive polymers and compositions comprising the same. In some embodiments, the polymers are water soluble, pH-degradable and have tunable lower critical solution temperatures. Other aspects of the invention include micelles and gels comprising the thermo-responsive polymers and derivatives thereof, as well as methods of delivering therapeutic agents comprising administering a biodegradable gel or micelle comprising a polyacetal compound cross-linked with a linker. |
| FILED | Thursday, December 03, 2015 |
| APPL NO | 15/532405 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/04 (20130101) A01N 25/10 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/1075 (20130101) A61K 31/7068 (20130101) A61K 47/59 (20170801) A61K 47/60 (20170801) Original (OR) Class A61K 47/6907 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/18 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/48 (20130101) C08G 65/33396 (20130101) C08G 81/00 (20130101) C08G 2230/00 (20130101) C08G 2650/04 (20130101) C08G 2650/30 (20130101) C08G 2650/44 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/24 (20130101) C08J 3/075 (20130101) C08J 2371/08 (20130101) Compositions of Macromolecular Compounds C08L 33/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11331627 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Qilin Li (Houston, Texas); Jinjian Wu (Costa Mesa, California); Nancy C. Halas (Houston, Texas); Katherine R. Zodrow (Butte, Montana); Haoli Guo (Beijing, China PRC); Jiarui Xu (Houston, Texas); Cong Yu (Issaquah, Washington) |
| ABSTRACT | In some embodiments, the present disclosure pertains to systems and methods for distilling a fluid by exposing the fluid to a porous membrane that includes a surface capable of generating heat. In some embodiments, the heat generated at the surface propagates the distilling of the fluid by converting the fluid to a vapor that flows through the porous membrane and condenses to a distillate. In some embodiments, the surface capable of generating heat is associated with a photo-thermal composition that generates the heat at the surface by converting light energy from a light source to thermal energy. In some embodiments, the photo-thermal composition includes, without limitation, noble metals, semiconducting materials, dielectric materials, carbon-based materials, composite materials, nanocomposite materials, nanoparticles, hydrophilic materials, polymers, fibers, meshes, fiber meshes, hydrogels, hydrogel meshes, nanomaterials, and combinations thereof. Further embodiments pertain to methods of making the porous membranes of the present disclosure. |
| FILED | Monday, October 19, 2020 |
| APPL NO | 17/074305 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/364 (20130101) Original (OR) Class B01D 67/0088 (20130101) B01D 71/021 (20130101) B01D 71/022 (20130101) B01D 2313/36 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332245 | Mohseni et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Kamran Mohseni (Gainesville, Florida); Thomas I. Linehan (Gainesville, Florida) |
| ABSTRACT | A vehicle, such as a micro-aerial vehicle or underwater vehicle, includes at least one lift structure, such as a low-aspect-ratio wing or a fin, respectively. The at least one lift structure comprises one or more alulas. A leading surface of each alula is (a) flush with a leading surface of the lift structure or (b) offset from the leading edge of the lift surface by up to approximately 10% of the chord length of the lift structure. The length of each alula is no more than approximately 20% of a lift structure length corresponding to the lift structure. In various embodiments, the alula is deflected or canted with respect to a plane defined by the lift structure. In an example embodiment, the alulas may be slid or translated along at least a portion of the span of the lift structure. |
| FILED | Tuesday, December 10, 2019 |
| APPL NO | 16/709227 |
| ART UNIT | 3619 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 9/08 (20130101) B64C 9/22 (20130101) B64C 23/06 (20130101) B64C 39/028 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332426 | Hoveyda et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston College (Chestnut Hill, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston College (Chestnut Hill, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Amir H. Hoveyda (Lincoln, Massachusetts); Thach T. Nguyen (Newton, Massachusetts); Ming Joo Koh (Chestnut Hill, Massachusetts); Chaofan Xu (Brighton, Massachusetts); Sebastian Torker (Brighton, Massachusetts); Richard Royce Schrock (Winchester, Massachusetts) |
| ABSTRACT | Method of forming a trisubstituted ethylene compound, the method comprising: (A) providing a trisubstituted ethylene compound bearing a first, a second and a third substituent, in which the first and the second substituent are bound to the one olefinic carbon atom and are different from one another; (B) providing a monosubstituted ethylene compound or a disubstituted ethylene compound in which the substituents are vicinally bound to the olefinic carbon atoms, bearing at least a fourth substituent, respectively; (C) subjecting the trisubstituted ethylene compound provided in step (A) to a cross-metathesis reaction with olefin provided in step (B) to form said trisubstituted ethylene, wherein the cross-metathesis reaction is catalysed by a transition metal complex bearing ligands from which one ligand is a carbene ligand, wherein the carbene complex is characterized by a M=C moiety, wherein M is the transition metal; and wherein the reaction proceeds stereoselectively. |
| FILED | Friday, September 21, 2018 |
| APPL NO | 16/646479 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/2273 (20130101) B01J 2231/543 (20130101) B01J 2531/821 (20130101) Acyclic or Carbocyclic Compounds C07C 2/04 (20130101) C07C 6/02 (20130101) C07C 6/04 (20130101) C07C 41/30 (20130101) Original (OR) Class C07C 43/1787 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332546 | Ge et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of The University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Xin Ge (Manvel, Texas); Kibaek Lee (Houston, Texas) |
| ABSTRACT | Certain embodiments provide isolated anti-MMP-14 antibodies or fragments thereof, isolated anti-MMP-12 antibodies or fragments thereof, isolated anti-BACE-1 antibodies or fragments thereof, isolated anti-Alp2 antibodies or fragments thereof, and isolated anti-cathepsin B antibodies or fragments thereof, as well as methods of use thereof. |
| FILED | Thursday, May 21, 2020 |
| APPL NO | 16/880747 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/40 (20130101) Original (OR) Class C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332555 | Altenberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Texas Tech University System (Lubbock, Texas) |
| ASSIGNEE(S) | Texas Tech University System (Lubbock, Texas) |
| INVENTOR(S) | Guillermo A. Altenberg (Lubbock, Texas); Hongjun Liang (Lubbock, Texas) |
| ABSTRACT | The present invention includes compositions, methods, and methods of making and using a polymer-encased nanodisc comprising: one or more integral membrane proteins in a lipid layer; and a polymer comprising zwitterionic styrene-maleic acid derivative repeating units that carry zero or nearly zero negative charge, and the polymer-encased nanodiscs. |
| FILED | Wednesday, October 07, 2020 |
| APPL NO | 17/064687 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/38 (20130101) C08F 8/12 (20130101) C08F 8/12 (20130101) C08F 8/40 (20130101) Original (OR) Class C08F 8/44 (20130101) C08F 8/44 (20130101) C08F 212/08 (20130101) C08F 212/08 (20130101) C08F 222/06 (20130101) C08F 222/06 (20130101) C08F 222/08 (20130101) C08F 222/08 (20130101) C08F 2438/03 (20130101) Compositions of Macromolecular Compounds C08L 33/00 (20130101) C08L 33/26 (20130101) C08L 35/06 (20130101) C08L 89/00 (20130101) C08L 89/00 (20130101) C08L 89/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) C12N 9/96 (20130101) C12N 11/04 (20130101) C12N 11/082 (20200101) Enzymes C12Y 306/01003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332565 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ang Li (Baton Rouge, Louisiana); Guoqiang Li (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| INVENTOR(S) | Ang Li (Baton Rouge, Louisiana); Guoqiang Li (Baton Rouge, Louisiana) |
| ABSTRACT | A UV-curable and recyclable thermoset shape memory polymer is provided. The polymer includes a vitrimer-based monomer and a photoinitiator. The vitrimer-based monomer includes a first unit rendering a high chain stiffness upon polymerization of the monomer, and a second photopolymerizable unit for photopolymerization of the monomer under a UV irradiation. The polymer has high strength, high stiffness, high recovery stress, high energy storage, reasonable recycling efficiency, and is printable using SLA with high resolution. |
| FILED | Tuesday, April 30, 2019 |
| APPL NO | 17/051709 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/00 (20141201) B33Y 80/00 (20141201) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/50 (20130101) C08F 222/102 (20200201) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 11/04 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/05 (20130101) C08K 5/07 (20130101) C08K 5/17 (20130101) C08K 5/5397 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332751 | Shao et al. |
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| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Zengyi Shao (Ames, Iowa); Mingfeng Cao (Ames, Iowa); Miguel Suastegui (Ames, Iowa); Meirong Gao (Ames, Iowa) |
| ABSTRACT | The present disclosure includes methods and components for production of valuable industrial compounds in yeast. In an embodiment, the present invention provides a nucleic acid construct with increased stability for gene expression or gene editing comprising: a nucleic acid sequence encoding one or more of SEQ ID NO: 1-8 (CENs 1-8); and one or more regulatory elements functional in a yeast cell. In an embodiment of the present invention the nucleic acid constructs are vectors, preferably episomal vectors. High expression promoters, as well as methods for increasing production of compounds such as aromatics are disclosed. |
| FILED | Tuesday, July 28, 2020 |
| APPL NO | 16/947304 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0004 (20130101) C12N 9/10 (20130101) C12N 9/88 (20130101) C12N 15/81 (20130101) Original (OR) Class C12N 15/102 (20130101) C12N 2830/002 (20130101) C12N 2830/008 (20130101) C12N 2830/702 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/007 (20130101) C12P 7/42 (20130101) C12P 7/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332754 | Daniell |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Henry Daniell (Media, Pennsylvania) |
| ABSTRACT | Methods for improving transgene in chloroplasts are disclosed along with improved transgenes so produced and methods of use thereof for the treatment of disease. Specifically, the methods comprising analyzing the native sequence of a nucleic acid encoding a protein of interest and replacing codons in said sequence with those preferentially used in psbA genes in chloroplasts in higher plants. |
| FILED | Monday, March 20, 2017 |
| APPL NO | 16/086416 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0058 (20130101) A61K 39/12 (20130101) A61K 2039/542 (20130101) A61K 2039/545 (20130101) A61K 2039/575 (20130101) A61K 2039/6037 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/02 (20180101) A61P 31/14 (20180101) Peptides C07K 14/65 (20130101) C07K 14/755 (20130101) C07K 14/4723 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/2408 (20130101) C12N 15/8214 (20130101) C12N 15/8216 (20130101) C12N 15/8257 (20130101) C12N 15/8258 (20130101) Original (OR) Class C12N 2770/32634 (20130101) Enzymes C12Y 302/01084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333620 | Agyeman-Budu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | David N. Agyeman-Budu (Ithaca, New York); Joel D. Brock (Ithaca, New York); Arthur R. Woll (Ithaca, New York) |
| ABSTRACT | A high-pass x-ray filter device is disclosed that includes a substrate defining an elongated opening. A reflecting membrane is positioned across the opening and supported, along all sides, by the substrate. The reflecting membrane is configured to transmit, from an incident x-ray beam, x-ray photons having an energy above about a threshold energy level and reflects, from the incident x-ray beam, x-ray photons having an energy below about the threshold energy level. The elongated opening of the substrate defines an exit path for the transmitted x-ray beam. A high-pass x-ray filter system including the high-pass filter device and a method of fabrication of the high-pass filter device are also disclosed. |
| FILED | Monday, August 03, 2020 |
| APPL NO | 16/983887 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/046 (20130101) G01N 23/087 (20130101) Original (OR) Class G01N 2223/423 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333663 | Swager et al. |
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| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Timothy Manning Swager (Newton, Massachusetts); Joseph Michael Azzarelli (Cambridge, Massachusetts); Shinsuke Ishihara (Cambridge, Massachusetts) |
| ABSTRACT | A tag for detecting an analyte can include a radio frequency identification tag including a sensor portion, the sensor portion configured to change resistivity when the radio frequency identification tag contacts or interacts with an analyte, whereby the resistivity change alters an output of the radio frequency identification tag, wherein the sensor portion includes a circuit, and wherein the sensor portion is configured to activate the circuit or deactivate the circuit when contacted or having interacted with the analyte, where the sensor portion includes a plurality of carbon nanotubes associated with a chemically-degradable polymer. In certain embodiments, the chemically degradable polymer can be a metallo-supramolecular polymer. |
| FILED | Thursday, May 07, 2020 |
| APPL NO | 16/869534 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/21 (20130101) G01N 21/78 (20130101) G01N 21/6428 (20130101) G01N 33/54386 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/07 (20130101) G06K 19/0717 (20130101) G06K 19/0723 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333667 | Tong |
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| FUNDED BY |
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| APPLICANT(S) | SAN DIEGO STATE UNIVERSITY FOUNDATION (San Diego, California) |
| ASSIGNEE(S) | SAN DIEGO STATE UNIVERSITY FOUNDATION (San Diego, California) |
| INVENTOR(S) | William G. Tong (La Jolla, California) |
| ABSTRACT | This patent document discloses techniques, systems, and devices for detecting a target substance using optical nonlinear wave mixing for enhanced detection sensitivity and accuracy. In one aspect, a method for measuring α-synuclein in a body fluid of a patient with high detection sensitivity and accuracy and providing early stage Parkinson's disease detection is provided. The method may comprise: supplying to a capillary analyte cell a fluidic sample that includes a body fluid of a patient containing α-synuclein, wherein the capillary analyte cell is located in a nonlinear optical four-wave mixing device; directing laser light from the nonlinear optical four-wave mixing device into the capillary analyte cell to cause nonlinear optical four-wave mixing in the fluidic sample to generate a four-wave mixing signal that contains information on the α-synuclein in the fluidic sample; and processing the four-wave mixing signal to extract information on the α-synuclein in the fluidic sample. |
| FILED | Tuesday, February 21, 2017 |
| APPL NO | 15/999856 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/03 (20130101) G01N 21/636 (20130101) G01N 21/718 (20130101) G01N 27/44791 (20130101) G01N 33/49 (20130101) G01N 33/582 (20130101) Original (OR) Class G01N 33/6896 (20130101) G01N 2021/0346 (20130101) G01N 2800/56 (20130101) G01N 2800/2835 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11334360 | Hu et al. |
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| FUNDED BY |
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| APPLICANT(S) | DEEPBITS TECHNOLOGY INC. (Riverside, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | DEEPBITS TECHNOLOGY INC. (Riverside, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Xunchao Hu (Riverside, California); Sheng Yu (Riverside, California); Heng Yin (Riverside, California) |
| ABSTRACT | The present invention performs high-throughput disassembly for executable code comprising a plurality of instructions. An input of the executable code is received. Exhaustive disassembly is performed on the executable code to produce a set of exhaustively disassembled instructions. An instruction flow graph is constructed from the exhaustively disassembled instructions. Instruction embedding is performed on the exhaustively disassembled instructions to construct embeddings. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/243570 |
| ART UNIT | 2182 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 8/53 (20130101) G06F 9/3838 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11334986 | Hearst et al. |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Anthony A. Hearst (Lafayette, Indiana); Keith A. Cherkauer (West Lafayette, Indiana); Katherine M. Rainey (West Lafayette, Indiana) |
| ABSTRACT | A method for processing images of an agricultural field is disclosed that enables accurate phenotype measurements for crops planted in each research plot of the agricultural field. The method comprises receiving a plurality of input images of the agricultural field, calculating and refining object space coordinates for matched key points in the input images and an object space camera pose for each input image, calculating and refining object space center points for the research plots based on a user-defined plot layout, and generating output images of individual research plots that are centered, cropped, orthorectified, and oriented in alignment with planted rows of crops. Based on the output images, accurate phenotype measurements for crops planted in each research plot can be determined. The method advantageously minimizes row-offset errors, variations in canopy cover and color between images, geometric and radiometric distortion, and computational memory requirements, while facilitating parallelized image processing and analysis. |
| FILED | Thursday, January 30, 2020 |
| APPL NO | 16/776767 |
| ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/001 (20130101) Original (OR) Class G06T 2207/30188 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11335781 | Eom et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Chang-Beom Eom (Madison, Wisconsin); Daesu Lee (Madison, Wisconsin) |
| ABSTRACT | Heterostructures that include a bilayer composed of epitaxial layers of vanadium dioxide having different rutile-to-monoclinic phase transition temperatures are provided. Also provided are electrical switches that incorporate the heterostructures. The bilayers are characterized in that they undergo a single-step, collective, metal-insulator transition at an electronic transition temperature. At temperatures below the electronic transition temperature, the layer of vanadium dioxide having the higher rutile-to-monoclinic phase transition temperature has an insulating monoclinic crystalline phase, which is converted to a metallic monoclinic crystalline phase at temperatures above the electronic transition temperature. |
| FILED | Wednesday, May 10, 2017 |
| APPL NO | 15/591454 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/24 (20130101) Original (OR) Class H01L 29/45 (20130101) H01L 29/94 (20130101) H01L 29/7869 (20130101) H01L 29/8611 (20130101) H01L 45/04 (20130101) H01L 45/146 (20130101) H01L 45/1226 (20130101) H01L 45/1233 (20130101) H01L 45/1253 (20130101) H01L 49/003 (20130101) Pulse Technique H03K 17/687 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11336228 | Fahs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Bassem Fahs (Troy, New York); Mona Hella (Troy, New York) |
| ABSTRACT | A high frequency push-push oscillator is disclosed. The high frequency push-push oscillator includes a resonant circuit, including tank transmission lines or an inductor capacitor (LC) tank circuit, for generating a differential signal having a resonant frequency, and a Gm-core circuit for converting the differential signal to an output signal having an output frequency that is higher than the resonant frequency. The Gm-core circuit includes cross-coupled first and second transistors having first and second gates, drains, and sources, respectively, and first and second gate transmission lines. The first and second drains are in electrical communication with the resonant circuit. The first gate transmission line is joined with the first gate and the resonant circuit and the second gate transmission line is joined with the second gate and the resonant circuit. The Gm-core circuit includes a differential transmission line positioned between the first and second gates of the first and second transistors. |
| FILED | Monday, July 10, 2017 |
| APPL NO | 16/316198 |
| ART UNIT | 2849 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 5/1212 (20130101) Original (OR) Class H03B 5/1228 (20130101) H03B 5/1841 (20130101) H03B 5/1852 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11336473 | Yeh et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Edmund Meng Yeh (Newton, Massachusetts); Milad Mahdian (New York, New York) |
| ABSTRACT | Embodiments include a unified framework for minimizing congestion-dependent network cost by jointly optimizing forwarding and caching strategies that account for link congestion between neighboring nodes. As caching variables are integer-constrained, the resulting optimization problem is a non-deterministic polynomial time (NP)-hard problem. Embodiments relax the optimization problem, where caching variables are real-valued. Embodiments include optimality conditions for the relaxed problem. Embodiments include an adaptive and distributed joint forwarding and caching method, based on a conditional gradient method. Embodiments elegantly yield feasible routing variables and integer caching variables at each iteration, and can be implemented in a distributed manner with low complexity and overhead. Over a wide range of network topologies, simulation results show that embodiments have significantly better delay performance in the low to moderate request rate regions. Furthermore, embodiments complement each other in delivering superior delay performance across the range of request arrival rates, compared to existing methods. |
| FILED | Friday, October 12, 2018 |
| APPL NO | 16/754067 |
| ART UNIT | 2469 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 12/1432 (20130101) Original (OR) Class H04L 67/32 (20130101) H04L 67/2842 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11336823 | Alshurafa et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Nabil I. Alshurafa (Chicago, Illinois); Josiah D. Hester (Evanston, Illinois) |
| ABSTRACT | A camera system includes a camera configured to capture first video of a scene in the form of first image frames. The camera system also includes an infrared sensor configured to capture second video of the scene in the form of second image frames. The system also includes a processor in communication with the camera and the infrared sensor. The processor is configured to obfuscate one or more portions of the scene. |
| FILED | Wednesday, September 02, 2020 |
| APPL NO | 17/010560 |
| ART UNIT | 2481 — Recording and Compression |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/003 (20130101) G06T 5/50 (20130101) G06T 7/194 (20170101) G06T 2207/10024 (20130101) G06T 2207/10048 (20130101) G06T 2207/20221 (20130101) Pictorial Communication, e.g Television H04N 5/76 (20130101) H04N 5/247 (20130101) H04N 5/272 (20130101) H04N 5/2252 (20130101) H04N 5/2253 (20130101) H04N 5/23229 (20130101) Original (OR) Class H04N 7/18 (20130101) H04N 9/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11331386 | Barouch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Dan H. Barouch (Boston, Massachusetts); Bette T. Korber (Los Alamos, New Mexico); William M. Fischer (Los Alamos, New Mexico) |
| ABSTRACT | The invention provides compositions, methods, and kits for the treatment or prevention of viral infections. The polyvalent (e.g., 2-valent) vaccines described herein incorporate computationally-optimized viral polypeptides that can increase the diversity or breadth and depth of cellular immune response in vaccinated subjects. |
| FILED | Thursday, September 10, 2020 |
| APPL NO | 16/948257 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) Original (OR) Class A61K 39/235 (20130101) A61K 39/275 (20130101) A61K 2039/53 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10043 (20130101) C12N 2710/10343 (20130101) C12N 2710/24043 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) C12N 2740/16171 (20130101) C12N 2740/16222 (20130101) C12N 2740/16234 (20130101) C12N 2740/16271 (20130101) C12N 2740/16322 (20130101) C12N 2740/16334 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332482 | Toste et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | F. Dean Toste (Piedmont, California); Mark Daniel Levin (Chicago, Illinois); James Patrick O'Neil (San Leandro, California) |
| ABSTRACT | Au(III) complexes for [18F] trifluoromethylation and methods for producing the same are disclosed. A gold complex comprises Au(CF3)2LR, wherein L comprises a solubility supporting ligand and R comprises an organic substituent. The Au(III) complex can be used to prepare a positron emitting isotope that can be used as tracers for positron emitting tomography (PET) scans. |
| FILED | Monday, May 21, 2018 |
| APPL NO | 16/615248 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0497 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332763 | Singh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Raghuveer Singh (Lincoln, Nebraska); Derrick White (Lincoln, Nebraska); Paul Blum (Lincoln, Nebraska) |
| ABSTRACT | This disclosure describes methods that allow for the uncoupling of microbial growth from product formation, which allows for maximal use of raw material and optimal end-product formation. |
| FILED | Thursday, April 21, 2016 |
| APPL NO | 15/568347 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/36 (20130101) C12N 1/185 (20210501) C12N 1/205 (20210501) C12N 9/0006 (20130101) C12N 9/88 (20130101) C12N 9/1217 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 3/00 (20130101) C12P 7/44 (20130101) C12P 7/54 (20130101) C12P 7/065 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/15 (20210501) C12R 2001/145 (20210501) C12R 2001/865 (20210501) Enzymes C12Y 101/01027 (20130101) C12Y 207/02001 (20130101) C12Y 401/0103 (20130101) C12Y 401/01039 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332972 | Briese et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GED INTEGRATED SOLUTIONS, INC. (Glenwillow, Ohio) |
| ASSIGNEE(S) | GED Integrated Solutions, Inc. (Twinsburg, Ohio) |
| INVENTOR(S) | William A. Briese (Hinckley, Ohio); John Grismer (Cuyahoga Falls, Ohio); Timothy B. McGlinchy (Twinsburg, Ohio) |
| ABSTRACT | This invention describes an apparatus for assembling triple pane insulating glass units from a plurality of insulating spacer frames having sealant or adhesive applied to opposite sides of said spacer frames. |
| FILED | Wednesday, June 12, 2019 |
| APPL NO | 16/439051 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 3/673 (20130101) E06B 3/66328 (20130101) E06B 3/66333 (20130101) E06B 3/67326 (20130101) E06B 3/67365 (20130101) E06B 3/67382 (20130101) E06B 3/67386 (20130101) Original (OR) Class E06B 2003/66338 (20130101) E06B 2003/66395 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/534 (20150115) Y10T 29/5137 (20150115) Y10T 29/5142 (20150115) Y10T 29/49792 (20150115) Y10T 29/49826 (20150115) Y10T 29/49892 (20150115) Y10T 29/49906 (20150115) Y10T 29/53417 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333024 | Dutta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| INVENTOR(S) | Sandip Dutta (Greenville, South Carolina); James Zhang (Greenville, South Carolina); Gary Michael Itzel (Simpsonville, South Carolina); John McConnell Delvaux (Fountain Inn, South Carolina); Matthew Troy Hafner (Honea Path, South Carolina) |
| ABSTRACT | A turbine component includes a root and an airfoil extending from the root to a tip opposite the root. The airfoil forms a leading edge and a trailing edge portion extending to a trailing edge. Radial cooling channels in the trailing edge portion of the airfoil permit radial flow of a cooling fluid through the trailing edge portion. Each radial cooling channel has a first end at a lower surface at a root edge of the trailing edge portion or at an upper surface at a tip edge of the trailing edge portion and a second end opposite the first end at the lower surface or the upper surface. A method of making a turbine component and a method of cooling a turbine component are also disclosed. |
| FILED | Friday, October 18, 2019 |
| APPL NO | 16/656650 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/147 (20130101) F01D 5/187 (20130101) Original (OR) Class F01D 5/282 (20130101) F01D 9/02 (20130101) F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/30 (20130101) F05D 2230/22 (20130101) F05D 2230/31 (20130101) F05D 2230/237 (20130101) F05D 2240/122 (20130101) F05D 2240/304 (20130101) F05D 2250/183 (20130101) F05D 2250/184 (20130101) F05D 2250/185 (20130101) F05D 2260/20 (20130101) F05D 2260/204 (20130101) F05D 2300/175 (20130101) F05D 2300/6033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333414 | Vetrovec |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jan Vetrovec (Larkspur, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jan Vetrovec (Larkspur, Colorado) |
| ABSTRACT | The invention is for an apparatus and method for a refrigerator and a heat pump based on the magnetocaloric effect (MCE) offering a simpler, lighter, robust, more compact, environmentally compatible, and energy efficient alternative to traditional vapor-compression devices. The subject magnetocaloric apparatus alternately exposes portions of an MCE material to strong and weak magnetic field while coordinating the heat flow between the exposed portions by heat bridges to move the heat up the thermal gradient. The invention may be practiced with multiple MCE material portions or segments to attain large differences in temperature. Key applications include thermal management of electronics, as well as industrial and home refrigeration, heating, and air conditioning. The invention offers a simpler, lighter, compact, and robust apparatus compared to magnetocaloric devices of prior art. Furthermore, the invention may be run in reverse as a thermodynamic engine, receiving low-level heat and producing mechanical energy. |
| FILED | Monday, January 27, 2020 |
| APPL NO | 16/873068 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 21/00 (20130101) Original (OR) Class F25B 2321/0021 (20130101) F25B 2321/0023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333807 | Nguyen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| INVENTOR(S) | Hoang T. Nguyen (Livermore, California); Jerald A. Britten (Clayton, California) |
| ABSTRACT | Metallic overcoated diffraction gratings are particularly useful for high average power laser pulse compression. A dielectric oxide layer is attached to an etch-stop layer, where the dielectric oxide layer comprises a grating pattern including grating lines. Sidewalls of the grating lines taper together toward an upper surface of the dielectric oxide layer. A metallic overcoat is attached to the etch-stop layer and the dielectric oxide layer. |
| FILED | Friday, June 01, 2018 |
| APPL NO | 16/620139 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/18 (20130101) Original (OR) Class G02B 5/1857 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333908 | Diroll et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Benjamin Diroll (Chicago, Illinois); Richard D. Schaller (Clarendon Hills, Illinois) |
| ABSTRACT | Colloidal quantum wells have discrete energy states and electrons in the quantum wells undergo interband and intersubband state transitions. The transmissivity of a colloidal quantum well may be tuned by actively controlling the states of the colloidal quantum wells enabling ultrafast optical switching. A primary excitation source is configured to provide a primary excitation to promote a colloidal quantum well from a ground state to a first excitation state. A secondary excitation source is configured to provide a secondary excitation to the colloidal quantum well to promote the colloidal quantum well from the first excitation state to the second excitation state with the first and second excitation states being subbands in the conduction band of the colloidal quantum well. |
| FILED | Wednesday, June 05, 2019 |
| APPL NO | 16/431777 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0157 (20210101) G02F 1/01716 (20130101) Original (OR) Class G02F 1/3556 (20130101) G02F 2202/106 (20130101) G02F 2202/107 (20130101) G02F 2202/108 (20130101) G02F 2203/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11334069 | Buerger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Stephen Buerger (Albuquerque, New Mexico); Joshua Alan Love (Redondo Beach, California) |
| ABSTRACT | Systems, methods and unmanned agents for collaboratively controlling agents in a collaborative network by one or more agents continuously simulating numeric models of one or more other agents in the network to dramatically reduce the computational bandwidth required between agents, and improve the quality of shared estimates of the agent locations as well as the locations and characteristics of other objects of interest, e.g. targets. Bandwidth is reduced by using the models to intelligently filter data before communicating. |
| FILED | Wednesday, March 01, 2017 |
| APPL NO | 15/446772 |
| ART UNIT | 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0077 (20130101) G05D 1/0088 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 41/046 (20130101) H04L 41/048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11335470 | Oka et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Jude M. Oka (Espanola, New Mexico); Timothy A. Stone (White Rock, New Mexico) |
| ABSTRACT | A container having two different closing mechanism designs including an upright strike-less latch design and a Buttress thread design. |
| FILED | Friday, January 08, 2021 |
| APPL NO | 17/145127 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 5/12 (20130101) Original (OR) Class G21F 5/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11335649 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia) |
| ASSIGNEE(S) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia) |
| INVENTOR(S) | Jun Wang (Blacksburg, Virginia); Rolando Burgos (Blacksburg, Virginia); Dushan Boroyevich (Blacksburg, Virginia); Joshua Stewart (Blacksburg, Virginia); Yue Xu (Falls Church, Virginia) |
| ABSTRACT | Various embodiments of laminated planar bus structures that minimize electromagnetic interference (EMI) and parasitic inductance are described. In one embodiment, a laminated planar bus structure may include a plurality of stacked conductive layers and a plurality of stacked insulation layers. The plurality of stacked conductive layers may include positive and negative conductive layers, and conductive ground layers stacked as outer layers as to enclose vertically the positive and the negative conductive layers. In another embodiment, the laminated planar bus structure may include a middle ground layer stacked in between the positive and the negative conductive layers to provide additional reduction in electric field strength. A laminated planar bus structure that is integrated with other power electronics components is also presented. |
| FILED | Wednesday, May 20, 2020 |
| APPL NO | 16/879078 |
| ART UNIT | 2899 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/50 (20130101) H01L 23/60 (20130101) Original (OR) Class H01L 23/5227 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11335845 | Garten et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Lawrence Berkeley National Laboratory (Berkeley, California); The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); The Regents of the University of California (Oakland, California); The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Lauren Marie Garten (Camp Springs, Maryland); David Samuel Ginley (Evergreen, Colorado); Kristin Aslaug Ceder-Persson (Orinda, California); Shyam Sundar Dwaraknath (Berkeley, California); Susan Trolier-McKinstry (State College, Pennsylvania) |
| ABSTRACT | Methods for making metastable lead-free piezoelectric materials are presented herein. |
| FILED | Wednesday, January 23, 2019 |
| APPL NO | 16/255069 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 27/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/70 (20130101) C01P 2002/90 (20130101) C01P 2004/04 (20130101) C01P 2006/40 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/48 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 23/02 (20130101) C30B 23/025 (20130101) C30B 23/066 (20130101) C30B 29/22 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/316 (20130101) H01L 41/1871 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11335865 | Li |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Jian Li (Tempe, Arizona) |
| ABSTRACT | The present invention relates to organic light emitting devices with a multi-emissive material layer (EML), where a multi-EML generally refers to an emissive layer having at least two layers of emissive material, each layer having a different emitter concentration (e.g. a first EML in direct contact with a second EML, and the emitter concentration of the first EML (hole favorable) exceeds that of the second EML (electron favorable)). |
| FILED | Friday, April 14, 2017 |
| APPL NO | 15/487476 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 11/025 (20130101) C09K 2211/185 (20130101) C09K 2211/1007 (20130101) C09K 2211/1011 (20130101) C09K 2211/1014 (20130101) C09K 2211/1029 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0052 (20130101) H01L 51/0054 (20130101) H01L 51/0055 (20130101) H01L 51/0056 (20130101) H01L 51/0057 (20130101) H01L 51/0058 (20130101) H01L 51/0072 (20130101) H01L 51/0084 (20130101) H01L 51/0087 (20130101) Original (OR) Class H01L 51/504 (20130101) H01L 51/5008 (20130101) H01L 51/5096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11335932 | Park et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Eun Joo Park (Los Alamos, New Mexico); Yu Seung Kim (Los Alamos, New Mexico) |
| ABSTRACT | The present disclosure provides phosphonated polymers that can be used, for example, as polymer electrolyte membranes (PEMs) and/or catalyst ionomeric binders for electrodes in PEM fuel cells, and more particularly for high-temperature PEM fuel cells. High-temperature PEM fuel cells that use phosphonated polymers of the present disclosure suffer from reduced or no acid leaching because, in at least some examples, phosphonic acid moieties are covalently bound to the backbone of the polymers. A phosphonated polymer include a backbone having one or more aromatic monomers, with each aromatic monomer having one or more phosphonic acid groups. A phosphonic acid group may include phosphonic acid or a functional group that is hydrolysable into phosphonic acid. |
| FILED | Friday, May 08, 2020 |
| APPL NO | 16/869885 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/02 (20130101) C08G 2261/147 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/1023 (20130101) H01M 8/1065 (20130101) Original (OR) Class H01M 2250/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11335975 | Smirnov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NM Devices LLC (Las Cruces, New Mexico); General Graphene Corporation (Knoxville, Tennessee); Pavan Chaturvedi (Las Cruces, New Mexico); Dhanraj Shinde (Las Cruces, New Mexico) |
| ASSIGNEE(S) | NM DEVICES LLC (Las Cruces, New Mexico); GENERAL GRAPHENE CORPORATION (Knoxville, Tennessee); PAVAN CHATURVEDI (Las Cruces, New Mexico) |
| INVENTOR(S) | Sergei Smirnov (Las Cruces, New Mexico); Ivan Vlassiouk (Oak Ridge, Tennessee); Pavan Chaturvedi (Las Cruces, New Mexico); Dhanraj Shinde (Las Cruces, New Mexico) |
| ABSTRACT | Proton conductive membrane includes a proton selective layer of 80-100% carbon with sp2 hybridization having a thickness of 0.3-100 nm, with 0-20% of hydrogen, oxygen, nitrogen and sp3 carbon; wherein the sp2 carbon is in a form of graphene-like material; the proton selective layer having a plurality of pores formed by any of 7, 8, 9 or 10 sp2 carbon cycles or a combination thereof, with the pores having an effective diameter of up to 0.6 nm; an ionomeric polymer layer on the proton selective layer. Total thickness of the proton conductive membrane is less than 50 microns. The ionomeric polymer is PFSA (perfluorinated sulfonic acid), PVP (polyvinylpyrrolidone) or PVA (poly vinyl alcohol) with iodide or bromide counterion dissolved inside. The graphene-like material is CVD graphene or reduced graphene oxide (rGO). A D to G Raman band ratio of the membrane is more than 0.1. |
| FILED | Sunday, June 21, 2020 |
| APPL NO | 16/907255 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/26 (20130101) C23C 16/56 (20130101) C23C 16/0281 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 50/403 (20210101) H01M 50/446 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11336224 | Ho |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Clifford K. Ho (Albuquerque, New Mexico) |
| ABSTRACT | Thermal receivers, systems, and methods are disclosed that efficiently capture concentrated solar energy into a plurality of heat absorption bodies for conversion into thermal energy. In an embodiment, the thermal receivers, systems, and methods enable simultaneous electricity conversion and thermal energy capture. The receiver design enables a high penetration of concentrated sunlight deep into the thermal receiver to increase light trapping and reduce thermal losses. The thermal receiver is integrated with a photovoltaic (PV) receiver platform that converts some of the incident light to electricity while passing the remaining light to the thermal receiver. In another embodiment, other thermal receivers, systems, and methods are disclosed that efficiently capture concentrated solar energy into a sheet of falling particles. In an embodiment, the thermal receivers, systems, and methods enable simultaneous electricity conversion and thermal energy capture. |
| FILED | Wednesday, June 12, 2019 |
| APPL NO | 16/438604 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Solar Heat Collectors; Solar Heat Systems F24S 25/00 (20180501) F24S 70/10 (20180501) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/44 (20141201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11336244 | Dabrowski |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brookhaven Science Associates, LLC (Upton, New York) |
| ASSIGNEE(S) | Brookhaven Science Associates, LLC (Upton, New York) |
| INVENTOR(S) | Mieczyslaw M. Dabrowski (Port Jefferson, New York) |
| ABSTRACT | A fully differential rail-to-rail-output amplifier includes a differential input inverter pair, folded cascode pair, class AB control pair, and class AB output rail-to-rail pair. A drain associated with the folded cascode pair is operatively coupled to the class AB control pair, and the drain associated with the folded cascode pair is unconnected to the current source associated with the class AB control pair. A method of providing fully differential rail-to-rail-output amplification includes coupling a folded cascode pair operatively to a differential input inverter pair, coupling a drain associated with the folded cascode pair operatively to a class AB control pair, and coupling a class AB output rail-to-rail pair operatively to the class AB control pair. |
| FILED | Friday, July 10, 2020 |
| APPL NO | 16/925431 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Amplifiers H03F 3/45192 (20130101) H03F 3/45206 (20130101) Original (OR) Class H03F 3/45246 (20130101) H03F 3/45475 (20130101) H03F 2203/45028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11336659 | Ramanujan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| INVENTOR(S) | Ranga Ramanujan (Medina, Minnesota); Benjamin L. Burnett (Prior Lake, Minnesota) |
| ABSTRACT | This disclosure is directed to monitoring a crypto-partitioned, or cipher-text, wide-area network (WAN). A first computing device may be situated in a plain-text portion of a first enclave behind a first inline network encryptor (INE). A second device may be positioned in a plain-text portion of a second enclave behind a second INE. The two enclaves may be separated by a cipher-text WAN, over which the two enclaved may communicate. The first computing device may receive a data packet from the second computing device. The first computing device may then determine contents of a header of the data packet. The first computing device may, based at least in part on the contents of the header of the data packet, determine a status of the cipher-text WAN. |
| FILED | Thursday, April 23, 2020 |
| APPL NO | 16/856843 |
| ART UNIT | 2498 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 12/2854 (20130101) H04L 63/1408 (20130101) Original (OR) Class H04L 63/1441 (20130101) H04L 63/1458 (20130101) H04L 63/1483 (20130101) H04L 69/22 (20130101) H04L 2463/121 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11336690 | Urias et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Vincent Urias (Albuquerque, New Mexico); David Jakob Fritz (Fort Collins, Colorado); Michael Kunz (Gretna, Nebraska); Caleb Loverro (Albuquerque, New Mexico) |
| ABSTRACT | A method for emulating threats in virtual network computing environment is provided. The method comprises creating a number of virtual machines in the virtual network computing environment. A number of threat actors are emulated, wherein each threat actor comprises a number of threat artifacts that form a sequence of attack steps against the virtual network computing environment. The threat actors are then deployed against the virtual network computing environment. Behavioral data about actions of the threat actors in the virtual network computing environment is collected, as is performance data about the virtual network computing environment in response to the threat actors. The collected behavioral and performance data is then presented to a user via an interface. |
| FILED | Friday, November 15, 2019 |
| APPL NO | 16/685907 |
| ART UNIT | 2494 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 9/45558 (20130101) G06F 2009/45562 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1433 (20130101) H04L 63/1491 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11331747 | Cobb |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Josef Benjamin Cobb (Huntsville, Alabama) |
| ABSTRACT | A self-reacting friction stir welding (SR-FSW) tool includes a crown shoulder having a central bore and a pin that extends through the crown shoulder's central bore. The central bore includes a first region at a first axial end of the crown shoulder, a second region axially adjacent to the first region, and a third region axially adjacent to the second region. The first region and third region have a diameter that provides sliding contact with the pin. The pin and crown shoulder have an annular gap there between at the second region of the central bore. |
| FILED | Monday, June 22, 2020 |
| APPL NO | 16/908219 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 20/1255 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332228 | Church et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aurora Flight Sciences Corporation (Manassas, Virginia) |
| ASSIGNEE(S) | Aurora Flight Sciences Corporation (Manassas, Virginia) |
| INVENTOR(S) | Clint Church (Manassas, Virginia); Jeffrey Chambers (Manassas, Virginia) |
| ABSTRACT | A wide-body aircraft is disclosed with a fuselage section that includes a set of side-by-side fuselage lobes having a fuselage skin. A first woven composite preform positioned at a first intersection of the set of side-by-side fuselage lobes located at a first cusp of the side-by-side fuselage lobes. A second woven composite preform positioned at a second intersection of the set of side-by-side fuselage lobes located at a second cusp of the side-by-side fuselage lobes. Each of the first and second woven composite preforms are configured to receive a structural component, such that each of the first and second woven composite preforms accommodates vertical load imparted through the structural component. |
| FILED | Friday, April 06, 2018 |
| APPL NO | 15/946879 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 1/00 (20130101) B64C 1/12 (20130101) B64C 1/061 (20130101) Original (OR) Class B64C 1/069 (20130101) B64C 2001/0036 (20130101) B64C 2001/0045 (20130101) B64C 2001/0072 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11332419 | Robinson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kirtland Robinson (Tempe, Arizona); Ian Gould (Phoenix, Arizona); Christiana Bockisch (Tempe, Arizona); Everett Shock (Scottsdale, Arizona); Hilairy Hartnett (Phoenix, Arizona); Lynda B. Williams (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Kirtland Robinson (Tempe, Arizona); Ian Gould (Phoenix, Arizona); Christiana Bockisch (Tempe, Arizona); Everett Shock (Scottsdale, Arizona); Hilairy Hartnett (Phoenix, Arizona); Lynda B. Williams (Tempe, Arizona) |
| ABSTRACT | Synthesizing an alkane includes heating a mixture including an alkene and water at or above the water vapor saturation pressure in the presence of a catalyst and one or both of hydrogen and a reductant, thereby hydrogenating the alkene to yield an alkane and water, and separating the alkane from the water to yield the alkane. The reductant includes a first metal and the catalyst includes a second metal. |
| FILED | Wednesday, September 30, 2020 |
| APPL NO | 17/038602 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/755 (20130101) Acyclic or Carbocyclic Compounds C07C 1/24 (20130101) C07C 5/03 (20130101) Original (OR) Class C07C 2523/745 (20130101) C07C 2523/755 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333105 | Gradl et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Paul R. Gradl (Owens Cross Roads, Alabama); William C. C. Brandsmeier (Owens Cross Roads, Alabama); Sandra Elam Greene (Huntsville, Alabama); Justin R. Jackson (Huntsville, Alabama); Cory R. Medina (Albuquerque, New Mexico); Omar R. Mireles (Vestavia Hills, Alabama); Christopher Stephen Protz (Huntsville, Alabama) |
| ABSTRACT | A thrust chamber liner includes a metallic combustion chamber having an annular protrusion extending radially away from an exterior surface of the combustion chamber adjacent to its injector opening. A metallic nozzle is coupled to the combustion chamber at its throat opening. A composite material encases the exterior surface of the combustion chamber, but is only bonded to the annular protrusion. |
| FILED | Tuesday, April 28, 2020 |
| APPL NO | 16/860989 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/00 (20210101) B22F 2301/10 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Alloys C22C 9/06 (20130101) Jet-propulsion Plants F02K 9/62 (20130101) Original (OR) Class F02K 9/97 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11333581 | DiCicco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Joseph DiCicco (Cape May Court House, New Jersey); Paul Flanigan (Northfield, New Jersey); Joshua Stroker (Somers Point, New Jersey); James Deline (Egg Harbor City, New Jersey) |
| ABSTRACT | An alignment tool has a body with a top cavity. The top cavity is open on a top side and configured to receive the dispenser housing of a dispenser or a sampling medium head of a sampling medium on which to place the dispenser housing. The sampling medium head has a sample collection area. The body has a bottom cavity configured to receive a hammer arm. The body has one or more sampling media cavities disposed between the top cavity and the bottom cavity, each configured to receive another sampling medium having a respective sample collection area. A barrier is disposed between the bottom cavity and other cavities including the top cavity and the one or more sampling media cavities. The top cavity and the one or more sampling media cavities are in communication with each other via a common slot extending from the top cavity to the barrier. The top cavity and the one or more sampling media cavities are configured to receive a plurality of different sampling media and to align the dispenser housing with the sample collection area of each of the different sampling media. |
| FILED | Thursday, July 08, 2021 |
| APPL NO | 17/370746 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/02 (20130101) Original (OR) Class G01N 2001/022 (20130101) G01N 2001/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11333667 | Tong |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SAN DIEGO STATE UNIVERSITY FOUNDATION (San Diego, California) |
| ASSIGNEE(S) | SAN DIEGO STATE UNIVERSITY FOUNDATION (San Diego, California) |
| INVENTOR(S) | William G. Tong (La Jolla, California) |
| ABSTRACT | This patent document discloses techniques, systems, and devices for detecting a target substance using optical nonlinear wave mixing for enhanced detection sensitivity and accuracy. In one aspect, a method for measuring α-synuclein in a body fluid of a patient with high detection sensitivity and accuracy and providing early stage Parkinson's disease detection is provided. The method may comprise: supplying to a capillary analyte cell a fluidic sample that includes a body fluid of a patient containing α-synuclein, wherein the capillary analyte cell is located in a nonlinear optical four-wave mixing device; directing laser light from the nonlinear optical four-wave mixing device into the capillary analyte cell to cause nonlinear optical four-wave mixing in the fluidic sample to generate a four-wave mixing signal that contains information on the α-synuclein in the fluidic sample; and processing the four-wave mixing signal to extract information on the α-synuclein in the fluidic sample. |
| FILED | Tuesday, February 21, 2017 |
| APPL NO | 15/999856 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/03 (20130101) G01N 21/636 (20130101) G01N 21/718 (20130101) G01N 27/44791 (20130101) G01N 33/49 (20130101) G01N 33/582 (20130101) Original (OR) Class G01N 33/6896 (20130101) G01N 2021/0346 (20130101) G01N 2800/56 (20130101) G01N 2800/2835 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 11335657 | Colgan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Evan Colgan (Montvale, New Jersey); Timothy J. Chainer (Putnam Valley, New York); Monty Montague Denneau (Putnam, New York); Kai Schleupen (Yorktown Heights, New York); Diego Anzola (Burlington, Vermont); Mark D. Schultz (Ossining, New York); Layne A. Berge (Rochester, New York) |
| ABSTRACT | A data processing system includes a first wafer comprising a plurality of first chips, and kerf and crack-stop structures around perimeters of the first chips, and a second wafer comprising a plurality second chips, a plurality of interconnect structures through a connection zone between the second chips, and a plurality of thru silicon vias, wherein the first wafer and the second wafer are bonded face-to-face such that the interconnect structures of the second wafer electrically connect adjacent chip sites of the first wafer and where a pitch of the chips on the first and second wafer are equal. |
| FILED | Wednesday, September 16, 2020 |
| APPL NO | 17/023297 |
| ART UNIT | 2819 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/481 (20130101) H01L 23/544 (20130101) H01L 23/562 (20130101) H01L 24/08 (20130101) Original (OR) Class H01L 25/0657 (20130101) H01L 2223/5446 (20130101) H01L 2224/08145 (20130101) H01L 2225/06541 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11336476 | Klenk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NVIDIA Corporation (Santa Clara, California) |
| ASSIGNEE(S) | NVIDIA Corporation (Santa Clara, California) |
| INVENTOR(S) | Benjamin Klenk (San Jose, California); Nan Jiang (Santa Clara, California); Larry Robert Dennison (Menden, Massachusetts); Gregory M. Thorson (Palo Alto, California) |
| ABSTRACT | A network device configured to perform scalable, in-network computations is described. The network device is configured to process pull requests and/or push requests from a plurality of endpoints connected to the network. A collective communication primitive from a particular endpoint can be received at a network device. The collective communication primitive is associated with a multicast region of a shared global address space and is mapped to a plurality of participating endpoints. The network device is configured to perform an in-network computation based on information received from the participating endpoints before forwarding a response to the collective communication primitive back to one or more of the participating endpoints. The endpoints can inject pull requests (e.g., load commands) and/or push requests (e.g., store commands) into the network. A multicast capability enables tasks, such as a reduction operation, to be offloaded to hardware in the network device. |
| FILED | Friday, July 24, 2020 |
| APPL NO | 16/938156 |
| ART UNIT | 2415 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 9/5083 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 12/18 (20130101) H04L 12/1886 (20130101) Original (OR) Class H04L 45/74 (20130101) H04L 47/20 (20130101) H04L 47/39 (20130101) H04L 47/806 (20130101) H04L 67/26 (20130101) H04L 67/2842 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11330833 | Wise et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David J. Wise (Stoneville, Mississippi); Gary Daniel Chesser (Starkville, Mississippi); John Wesley Lowe (Houston, Mississippi); Todd Byars (Belzoni, Mississippi); Terrence Greenway (Stoneville, Mississippi); Jeremiah Davis (Auburn, Alabama); Joseph Purswell (Starkville, Mississippi) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David J. Wise (Stoneville, Mississippi); Gary Daniel Chesser (Starkville, Mississippi); John Wesley Lowe (Houston, Mississippi); Todd Byars (Belzoni, Mississippi); Terrence Greenway (Stoneville, Mississippi); Jeremiah Davis (Auburn, Alabama); Joseph Purswell (Starkville, Mississippi) |
| ABSTRACT | The invention consists of novel systems and methods for mixing and/or applying biologies including live biologies and/or any additive having therapeutic or growth promoting value with and/or to animal feed, thereby creating treated animal feed, and for delivering such treated animal feed to animals in need via a delivery system. The invention also provides a system and method to treat seed with biologies prior to or contemporaneously with packaging, storing, and/or planting. |
| FILED | Wednesday, December 14, 2016 |
| APPL NO | 16/062580 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 5/002 (20130101) A01K 5/005 (20130101) Machines or Apparatus for Treating Harvested Fruit, Vegetables or Flower Bulbs in Bulk, Not Otherwise Provided For; Peeling Vegetables or Fruit in Bulk; Apparatus for Preparing Animal Feeding- Stuffs A23N 17/00 (20130101) A23N 17/001 (20130101) Original (OR) Class A23N 17/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 11336377 | Papp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado); Government of the United States of America as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado); Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| INVENTOR(S) | Scott B. Papp (Boulder, Colorado); Jizhao Zang (Boulder, Colorado) |
| ABSTRACT | A millimeter-wave frequency synthesizer generates a millimeter wave by photomixing two Kerr-soliton microcombs. A single-frequency laser beam is modulated to create first and second pump components having first and second pump frequencies. The first pump component excites a first microresonator to create a first microcomb while the second pump component excites a second microresonator to generate a second microcomb. A pair of comb lines from the two microcombs is detected to generate a low-frequency beat note that is phase-locked by identically tuning the pump frequencies. Another pair of comb lines is detected with a high-speed photodiode to generate the millimeter wave. The frequency of the millimeter wave is based on (i) the difference between the pump frequencies, (ii) the difference between the repetition rates, and (iii) the index of the comb lines that are photomixed to generate the millimeter wave. |
| FILED | Tuesday, July 27, 2021 |
| APPL NO | 17/443647 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Transmission H04B 10/54 (20130101) H04B 10/58 (20130101) Original (OR) Class H04B 10/548 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Education (ED)
| US 11334803 | Luz Rello-Sanchez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Maria Luz Rello-Sanchez (Pittsburgh, Pennsylvania); Miguel Ballesteros (Pittsburgh, Pennsylvania) |
| ABSTRACT | This document describes a data processing system for processing a feature vector that comprises features (one or more) that are indicative of dyslexic behavior that are indicative of dyslexic behavior. The data processing system includes a feature classification engine that generates classification metrics for a feature vector. Machine learning logic is used to determine a classification metric for each feature. Features that have a classification metric below a pre-determined threshold are removed. The data processing system includes a prediction engine that generates a prediction value indicative of a predicted likelihood of dyslexia. The prediction engine assigns, to each remaining feature, based on the classification metric of the respective remaining feature, a prediction weight and determines the prediction value based on the prediction weights. |
| FILED | Thursday, April 20, 2017 |
| APPL NO | 15/493060 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/0445 (20130101) G06N 5/04 (20130101) Original (OR) Class G06N 20/00 (20190101) G06N 20/10 (20190101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 11332228 | Church et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aurora Flight Sciences Corporation (Manassas, Virginia) |
| ASSIGNEE(S) | Aurora Flight Sciences Corporation (Manassas, Virginia) |
| INVENTOR(S) | Clint Church (Manassas, Virginia); Jeffrey Chambers (Manassas, Virginia) |
| ABSTRACT | A wide-body aircraft is disclosed with a fuselage section that includes a set of side-by-side fuselage lobes having a fuselage skin. A first woven composite preform positioned at a first intersection of the set of side-by-side fuselage lobes located at a first cusp of the side-by-side fuselage lobes. A second woven composite preform positioned at a second intersection of the set of side-by-side fuselage lobes located at a second cusp of the side-by-side fuselage lobes. Each of the first and second woven composite preforms are configured to receive a structural component, such that each of the first and second woven composite preforms accommodates vertical load imparted through the structural component. |
| FILED | Friday, April 06, 2018 |
| APPL NO | 15/946879 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 1/00 (20130101) B64C 1/12 (20130101) B64C 1/061 (20130101) Original (OR) Class B64C 1/069 (20130101) B64C 2001/0036 (20130101) B64C 2001/0045 (20130101) B64C 2001/0072 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11331478 | Sabiev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Anton Sabiev (Forest Hills, New York); William Bauman (New Rochelle, New York); Mark Korsten (Hastings-on-Hudson, New York) |
| ABSTRACT | An iontophoresis system for positioning against skin of a subject is disclosed. The iontophoresis system can comprise at least one vessel having a solvent therein. An anode apparatus can couple to the at least one vessel. The anode apparatus can comprise a first reservoir configured to receive the solvent from the at least one vessel so that, when received into the first reservoir, the solvent makes contact with the skin of the subject, and a first electrode positioned above the first reservoir. A cathode apparatus can couple to the at least one vessel. The cathode apparatus can comprise a second reservoir configured to receive the solvent from the at least one vessel so that, when received into the first reservoir, the solvent makes contact with the skin of the subject, and a second electrode positioned above the second reservoir. |
| FILED | Friday, June 14, 2019 |
| APPL NO | 16/442082 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Endowment for the Humanities (NEH)
| US 11336883 | Willomitzer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Florian Willomitzer (Evanston, Illinois); Oliver Strider Cossairt (Evanston, Illinois); Marc Walton (Evanston, Illinois); Chia-Kai Yeh (Evanston, Illinois); Vikas Gupta (Fremont, California); William Spies (Arvada, Colorado); Florian Schiffers (Evanston, Illinois) |
| ABSTRACT | A three-dimensional (3D) imaging system includes a mobile device that has a display screen configured to display a series of patterns onto an object that is to be imaged. The mobile device also includes a front-facing camera configured to capture reflections of the series of patterns off of the object. The system also includes a controller that is configured to control a timing of the series of patterns that appear on the display screen and activation of the front-facing camera in relation to the appearance of the series of patterns. |
| FILED | Thursday, July 23, 2020 |
| APPL NO | 16/937045 |
| ART UNIT | 2482 — Recording and Compression |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 5/2253 (20130101) H04N 5/23218 (20180801) H04N 13/246 (20180501) H04N 13/254 (20180501) Original (OR) Class H04N 2013/0081 (20130101) H04N 2013/0096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 11333548 | Lal |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Amit Lal (Ithaca, New York) |
| ABSTRACT | A device configured for low-energy ultrasonic 2D Fourier transform analysis, comprising: (i) a first layer comprising an array of piezoelectric pixels; (ii) a second layer comprising an array of piezoelectric pixels; (iii) a third layer, positioned between the first and second layers, comprising a bulk ultrasonic transmission medium; wherein the second layer of array of piezoelectric pixels is in the Fourier plane of an input signal of the first layer array of piezoelectric pixels. |
| FILED | Thursday, May 23, 2019 |
| APPL NO | 17/057868 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 11/08 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/46 (20130101) G01N 2291/0426 (20130101) Electric Digital Data Processing G06F 17/142 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/18 (20130101) H01L 41/083 (20130101) Transmission H04B 11/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11332485 | Burns et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VenatoRx Pharmaceuticals, Inc. (Malvern, Pennsylvania) |
| ASSIGNEE(S) | VENATORX PHARMACEUTICALS, INC. (Malvern, Pennsylvania) |
| INVENTOR(S) | Christopher J. Burns (Malvern, Pennsylvania); Denis Daigle (Street, Maryland); Guo-Hua Chu (Exton, Pennsylvania); Jodie Hamrick (New Holland, Pennsylvania); Matthew Lucas (Cambridge, Massachusetts); Steven A. Boyd (Chester Springs, Pennsylvania); Allison L. Zulli (Chesterbrook, Pennsylvania); Eugen F. Mesaros (Wallingford, Pennsylvania); Stephen M. Condon (Glenmoore, Pennsylvania); Robert E. Lee Trout (Collegeville, Pennsylvania); Cullen L. Myers (Exton, Pennsylvania) |
| ABSTRACT | Described herein are certain boron-containing compounds, compositions, preparations and their use as modulators of the transpeptidase function of bacterial penicillin-binding proteins and as antibacterial agents. In some embodiments, the compounds described herein inhibit penicillin-binding proteins. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections. |
| FILED | Friday, May 25, 2018 |
| APPL NO | 16/616294 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/205 (20130101) A61K 9/2009 (20130101) A61K 9/2013 (20130101) A61K 9/2018 (20130101) A61K 9/2059 (20130101) A61K 9/4858 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/027 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Smithsonian Institution (SI)
| US 11333589 | Miller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Smithsonian Institution (Washington, District of Columbia) |
| ASSIGNEE(S) | Smithsonian Institution (Washington, District of Columbia) |
| INVENTOR(S) | Alexander Whitman Miller (Annapolis, Maryland); Amanda C. Reynolds (Annapolis, Maryland) |
| ABSTRACT | The current disclosure provides a gas-liquid falling film equilibration apparatus, systems incorporating the apparatus, and methods of their use. The apparatus comprises a chamber, an equilibration member within the chamber, liquid and gas inlet and outlets, such that a liquid introduced into the chamber from the liquid inlet contacts the upper portion of the outer surface of the equilibration member. The apparatus finds use in the measurement of dissolved gases in a variety of liquids including the measurement of carbon dioxide in water. |
| FILED | Thursday, March 21, 2019 |
| APPL NO | 16/980355 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/38 (20130101) Original (OR) Class G01N 33/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 11333793 | Hoff |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Clean Power Research, L.L.C. (Napa, California) |
| ASSIGNEE(S) | Clean Power Research, L.L.C. (Napa, California) |
| INVENTOR(S) | Thomas E. Hoff (Napa, California) |
| ABSTRACT | The calculation of the variance of a correlation coefficient matrix for a photovoltaic fleet can be completed in linear space as a function of decreasing distance between pairs of photovoltaic plant locations. When obtaining irradiance data from a satellite imagery source, irradiance statistics must first be converted from irradiance statistics for an area into irradiance statistics for an average point within a pixel in the satellite imagery. The average point statistics are then averaged across all satellite pixels to determine the average across the whole photovoltaic fleet region. Where pairs of photovoltaic systems are located too far away from each other to be statistically correlated, the correlation coefficients in the matrix for that pair of photovoltaic systems are effectively zero. Consequently, the double summation portion of the calculation can be simplified to eliminate zero values based on distance between photovoltaic plant locations, substantially decreasing the size of the problem space. |
| FILED | Friday, April 17, 2020 |
| APPL NO | 16/851687 |
| ART UNIT | 2864 — Printing/Measuring and Testing |
| CURRENT CPC | Meteorology G01W 1/02 (20130101) Original (OR) Class G01W 1/12 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/04 (20130101) G06Q 50/04 (20130101) Information and Communication Technology [ICT] Specially Adapted for Specific Application Fields, Not Otherwise Provided for G16Z 99/00 (20190201) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/38 (20130101) H02J 3/383 (20130101) H02J 2203/20 (20200101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 50/00 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/56 (20130101) Y02E 60/00 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 90/30 (20151101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 10/50 (20130101) Y04S 40/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11335522 | Carlberg |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Andrew Carlberg (Santa Maria, California) |
| ABSTRACT | A high power, single-use electrical switch includes a spring-biased plunger contact that mates with a corresponding socket contact, a spacer that provides a separation clearance between the contacts prior to activation of the switch, and a shear tab that supports the spacer and is removed from the switch to enable engagement between the contacts and activation of the switch. Using the shear tab for activation of the switch enables a compact and small form factor assembly that is suitable for use in smaller electronic assemblies. |
| FILED | Thursday, April 23, 2020 |
| APPL NO | 16/857072 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 27/00 (20130101) Original (OR) Class H01H 2227/024 (20130101) H01H 2239/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11336341 | Robinson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rampart Communications, Inc. (Annapolis, Maryland) |
| ASSIGNEE(S) | Rampart Communications, Inc. (Annapolis, Maryland) |
| INVENTOR(S) | Matthew Brandon Robinson (Crownsville, Maryland) |
| ABSTRACT | An apparatus includes a first communication device with multiple antennas, operably coupled to a processor and configured to access a codebook of transformation matrices. The processor generates a set of symbols based on an incoming data, and applies a permutation to each of the symbols to produce a set of permuted symbols. The processor transforms each of the permuted symbols based on at least one primitive transformation matrix, to produce a set of transformed symbols. The processor applies, to each of the transformed symbols, a precode matrix selected from the codebook of transformation matrices to produce a set of precoded symbols. The codebook of transformation matrices is accessible to a second communication device. The processor sends a signal to cause transmission, to the second communication device, of multiple signals, each representing a precoded symbol from the set of precoded symbols, each of the signals transmitted using a unique antenna from the plurality of antennas. |
| FILED | Wednesday, January 06, 2021 |
| APPL NO | 17/142702 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Transmission H04B 7/0456 (20130101) Original (OR) Class H04B 7/0491 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, May 17, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/details-patents-20220517.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page